OOIR: Observatory of International Research

Papers

(The median citation count of Esophagus is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Pre-existing and new-onset depression among patients undergoing esophageal cancer surgery: a nationwide cohort study in South Korea	159
Peroral endoscopic myotomy is equally safe and highly effective treatment option in achalasia patients with both lower and higher ASA classification status	69
Changes in and clinical utility of maximum phonation time and repetitive saliva swallowing test scores after esophagectomy	52
A nationwide survey on the safety of cricothyrotomy: a multicenter retrospective study in Japan	50
An anti-alcoholism drug, disulfiram and copper complex improves radio-resistance of tumor-initiating cells in esophageal squamous cell carcinoma	37
Endoscopic imaging modalities for diagnosing the invasion depth of superficial esophageal squamous cell carcinoma: a systematic review	27
Distal esophageal wall thickness correlates with dysphagia in adult patients with eosinophilic esophagitis	26
Clinical usefulness of sputum culture on the first postoperative day to predict early postoperative pneumonia after esophagectomy for esophageal cancer	23
The characteristics and prognostic significance of esophageal squamous cell carcinoma with synchronous multiple lesions: over 10-year experience	22
Betulin gel alleviates esophageal stricture following endoscopic submucosal dissection: an animal study	18
Survival impact of perioperative changes in prognostic nutritional index levels after esophagectomy	18
Multicenter phase II study of trifluridine/tipiracil for esophageal squamous carcinoma refractory/intolerant to 5-fluorouracil, platinum compounds, and taxanes: the ECTAS study	18
High rate of missed Barrett’s esophagus when screening with forceps biopsies	17
Endoscopic findings suggestive of a high risk of non-radical cure after definitive chemoradiotherapy for cT1bN0M0 esophageal squamous cell carcinoma	17
First-line pembrolizumab plus chemotherapy for advanced/metastatic esophageal cancer: 1-year extended follow-up in the Japanese subgroup of the phase 3 KEYNOTE-590 study	15
Reply to: The use of drugs to prevent postoperative delirium in elderly patients with radical esophagectomy	15
Saliva secretion is reduced in proton pump inhibitor-responsive non-erosive reflux disease patients	14
Five-year follow-up of nivolumab treatment in Japanese patients with esophageal squamous-cell carcinoma (ATTRACTION-1/ONO-4538-07)	13
Response to chemotherapy could predict the prognosis of esophageal squamous cell carcinoma treated with neoadjuvant docetaxel, cisplatin, and fluorouracil (DCF) followed by surgery: long-term results	13
Two onset types of achalasia and the long-term course to diagnosis	13
Is it meaningful to add mesh reinforcement to laparoscopic fundoplication for esophageal hiatal hernias in the patients with high risk of hiatal hernia recurrence?	13
Tumor response and survival outcomes of salvage concurrent chemoradiotherapy with three-dimensional conformal radiotherapy and 5-fluorouracil/platinum-based chemotherapy for postoperative locoregional	12
A simpler diagnostic algorithm of the Japan Esophageal Society classification for Barrett’s esophagus-related superficial neoplasia	12
Achalasia: laparoscopic Heller myotomy with fundoplication versus peroral endoscopic myotomy—a systematic review and meta-analysis	12
The impact of weight loss during neoadjuvant chemotherapy on postoperative infectious complications and prognosis in patients with esophageal cancer: exploratory analysis of OGSG1003	12

Usefulness of wearable fitness tracking devices in patients undergoing esophagectomy	12
Impact of pulmonary vein anatomy and left atrial size on postoperative atrial fibrillation after esophagectomy for esophageal cancer	11
Clinical predictors of special type of esophageal cancer	11
Usefulness of the preoperative inflammation-based prognostic score and the ratio of visceral fat area to psoas muscle area on predicting survival for surgically resected adenocarcinoma of the esophago	11
Modification of the lesser curvature incision line enhanced gastric conduit perfusion as determined by indocyanine green fluorescence imaging and decreased the incidence of anastomotic leakage followi	11
Preoperative docetaxel, cisplatin, and 5-fluorouracil for resectable locally advanced esophageal and esophagogastric junctional adenocarcinoma	11
Role of modified Glasgow Prognostic Score in patients with achalasia who underwent laparoscopic Heller-myotomy with Dor-fundoplication	11
Risk stratification for synchronous/metachronous recurrence after endoscopic submucosal dissection for Barrett’s esophageal adenocarcinoma using the length of Barrett’s esophagus	10
Significance of lymphovascular invasion in esophageal squamous cell carcinoma undergoing neoadjuvant chemotherapy followed by esophagectomy	10
Advancing high-resolution manometry: evaluating the use of multiple rapid swallows versus apple viscous swallows in clinical practice	10
Effect of chemoradiation on the development of second primary cancers after endoscopic resection of T1 esophageal squamous cell carcinoma	10
Impact of preoperative 6-minute walk distance on long-term prognosis after esophagectomy in patients with esophageal cancer	10
Stepwise innovation of anesthesia through endotracheal intubation during esophagectomy for cancer	10
Maximum standardized uptake value change rate before and after neoadjuvant chemotherapy can predict early recurrence in patients with locally advanced esophageal cancer: a multi-institutional cohort s	10
Second-line pembrolizumab versus chemotherapy in Japanese patients with advanced esophageal cancer: subgroup analysis from KEYNOTE-181	9
Biased expression of mutant alleles in cancer-related genes in esophageal squamous cell carcinoma	9
Effectiveness of taxanes following nivolumab in patients with advanced esophageal squamous cell carcinoma: a retrospective chart review of patients in ATTRACTION-3	9
Current status of prehabilitation before esophagectomy for patients with esophageal cancer among board-certified hospitals by the Japan Esophageal Society	9
Esophageal motility disorders missed during endoscopy	9
Multicenter retrospective analysis of complications and risk factors in endoscopic resection for esophageal cancer across Japan	8
Effectiveness of prehabilitation during neoadjuvant therapy for patients with esophageal or gastroesophageal junction cancer: a systematic review	8
Dynorphin participates in interaction between depression and non-erosive reflux disease	8
Efficacy of a novel small-caliber therapeutic endoscope in peroral endoscopic myotomy for esophageal motility disorders: a propensity score matching analysis	8
Outcome research on esophagectomy analyzed using nationwide databases in Japan: evidences generated from real-world data	7
Real-world treatment patterns and outcomes in Japanese patients with cervical esophageal cancer	7
Early versus delayed surgery following neoadjuvant chemoradiation for esophageal cancer: a systematic review and meta-analysis	7
First-line nivolumab plus ipilimumab or chemotherapy versus chemotherapy alone in advanced esophageal squamous cell carcinoma: a Japanese subgroup analysis of open-label, phase 3 trial (CheckMate 648/	7
Impact of taxanes after PD-1 blockade exposure in advanced esophageal squamous cell carcinoma	7
Novel endoscopic approaches using the endocytoscopy for the target biopsy in esophageal eosinophilia	6
International trends in esophageal cancer incidence rates by histological subtype (1990–2012) and prediction of the rates to 2030	6
A message from the new editor-in-chief 2024	6
Circulating exosome-derived miR-191-5p is a novel therapeutic biomarker for radiotherapy in esophageal squamous cell carcinoma patients	6
Celebrating 20 years of “Esophagus”	6
Safety and feasibility of esophagectomy following combined neoadjuvant immunotherapy and chemotherapy for locally advanced esophageal cancer: a propensity score matching	6
Correlation between TXNRD1/HO-1 expression and response to neoadjuvant chemoradiation therapy in patients with esophageal squamous cell carcinoma	6
Esophageal cancer practice guidelines 2022 edited by the Japan esophageal society: part 1	6
The potential for reducing alcohol consumption to prevent esophageal cancer morbidity in Asian heavy drinkers: a systematic review and meta-analysis	6
Outcomes of patients with esophageal squamous cell carcinoma who achieved a pathological complete response in the primary lesion by neoadjuvant treatment: a Japanese nationwide cohort study	5
Prognostic role of pathologic status other than complete response after neoadjuvant therapy followed by surgery in esophageal squamous cell carcinoma	5
Development of imaging biomarker for esophageal cancer using intravoxel incoherent motion MRI	5
Efficacy and survival of nivolumab treatment for recurrent/unresectable esophageal squamous-cell carcinoma: real-world clinical data from a large multi-institutional cohort	5
Optimizing neoadjuvant radiotherapy for locally advanced esophageal squamous cell carcinoma: a comprehensive review on the role of concomitant or sequential immune checkpoint inhibitors	5
Is oropharyngoesophageal scintigraphy the method of choice for assessing dysphagia in systemic sclerosis? A single center experience	5
No difference in the incidence of postoperative pulmonary complications between abdominal laparoscopy and laparotomy for minimally invasive thoracoscopic esophagectomy: a retrospective cohort study us	5
Japanese Classification of Esophageal Cancer, 12th Edition: Part I	5
Association of gastric myotomy length in peroral endoscopic myotomy (POEM) with gastro-esophageal junction distensibility measured by Endoluminal Functional Lumen Imaging Probe (EndoFLIP)	5
Early intervention of the perioperative multidisciplinary team approach decreases the adverse events during neoadjuvant chemotherapy for esophageal cancer patients	5
Validation of the cutoff values for the number of metastatic lymph nodes for esophageal cancer staging: a multi-institutional analysis of 655 patients in Japan	5
Safety and efficacy of double-tract reconstruction with remnant stomach conservation in esophagectomy for patients with a history of distal gastrectomy	5
Japanese Classification of Esophageal Cancer, 12th Edition: Part II	5

Long-term results after laparoscopic revision fundoplication: a retrospective, single-center analysis in 194 patients with recurrent hiatal hernia	5
Usefulness of prone-position computed tomography as preoperative simulation prior to thoracoscopic esophagectomy for thoracic esophageal cancer	5
Visceral fat obesity is the key risk factor for the development of reflux erosive esophagitis in 40–69-years subjects	5
Type B2 vessels and infiltrative growth patterns b and c are associated with lymphatic invasion in pT1a-lamina propria mucosa esophageal squamous cell carcinoma	5
Analysis of the short-term outcomes after esophagectomy for esophageal cancer during the COVID-19 pandemic using data from a nationwide Japanese database	5
A survey of the clinical outcomes of cervical esophageal carcinoma surgery focusing on the presence or absence of laryngectomy using the National Clinical Database in Japan	5
Comprehensive registry of esophageal cancer in Japan, 2014	4
Early tumor shrinkage and depth of response in patients with metastatic esophageal cancer treated with 2-weekly docetaxel combined with cisplatin plus fluorouracil: an exploratory analysis of the JCOG	4
Refining postoperative monitoring of recurrent laryngeal nerve injury in esophagectomy patients through transcutaneous laryngeal ultrasonography	4
Effect of sprayable, highly adhesive hydrophobized gelatin microparticles on esophageal stenosis after endoscopic submucosal dissection: an experimental study in a swine model	4
Risk of fractures in individuals with eosinophilic esophagitis: nationwide population-based cohort study	4
Risk factors and prognosis for esophageal fistula in patients with esophageal squamous cell carcinoma during radiotherapy	4
Risk prediction of esophageal squamous cell carcinoma recurrence in patients who underwent esophagectomy after receiving neoadjuvant treatment: a nationwide retrospective study in Japan	4
Relationship between esophageal achalasia subtypes and esophageal clearance	4
Safety and efficacy of endoscopic submucosal dissection for superficial esophageal cancer with esophageal varices	4
Development of a prediction score for Barrett’s esophagus in Japanese health checkup settings	4
Efficacy of laparoscopic fundoplication in patients with chronic cough and gastro-oesophageal reflux	4
The impact of combined PD-L1 positive score on clinical response to nivolumab in patients with advanced esophageal squamous cell carcinoma	4
Esophagectomy for esophageal cancer in patients with a history of total pharyngolaryngectomy: a Japanese nationwide retrospective cohort study	4
The effects of hesperidin on stricture formation in corrosive esophageal burns: an experimental study	4
Phase II study of BKM120 in patients with advanced esophageal squamous cell carcinoma (EPOC1303)	4
Clinical predictors of early postoperative recurrence after radical esophagectomy for thoracic esophageal cancer	4
Efficacy of thoracic endovascular aortic repair for aorto-esophageal fistula due to esophageal cancer: a systematic review and meta-analysis	4
Diagnosis of recurrent laryngeal nerve paralysis following esophagectomy by evaluating movement of the vocal cords and arytenoid cartilages using ultrasonography	4
Genomic analyses reveal SCN7A is associated with the prognosis of esophageal squamous cell carcinoma	4
Esophageal replacement when stomach conduit is unavailable: is colon the best option?	4
Urinary protein biomarker panel predicts esophageal squamous carcinoma from control cases and other tumors	3
Comprehensive complication index as a prognostic factor in minimally invasive esophagectomy for esophageal squamous cell carcinoma	3
Clinical characteristics of patients with eosinophilic esophagitis and eosinophilic esophageal myositis based on esophageal motility	3
Comprehensive registry of esophageal cancer in Japan, 2015	3
Implication of changes in PD-L1 expression during neoadjuvant chemotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF) regimen in esophageal squamous cell carcinoma	3
In females, salivary secretion was significantly lower in patients with severe reflux esophagitis than in healthy controls	3
A purely laparoscopic approach can reduce the incidence of postoperative pneumonia in esophageal cancer patients undergoing esophagectomy	3
Preoperative low serum creatine kinase is associated with poor overall survival in the male patients with esophageal squamous cell carcinoma	3
Critical swallowing functions contributing to dysphagia in patients with recurrent laryngeal nerve paralysis after esophagectomy	3
The prognostic significance of preoperative nutritional/inflammatory markers and clinicopathological features in resectable esophagectomy patients: possibility of nutritional intervention	3
Clinical outcomes and prognostic factors for esophageal cancer in patients aged 80 years or older who were treated with definitive radiotherapy and chemoradiotherapy	3
Predictors of the difficulty of transcervical subcarinal lymph node dissection for esophageal cancer	3
Significance of dissection in each regional lymph-node station of esophageal cancer based on efficacy index and recurrence patterns after curative esophagectomy	3
Prognostic impact of preoperative osteosarcopenia on esophageal cancer surgery outcomes: a retrospective analysis	3
Patient adverse events and technical failures with the bravo capsule pH system: insights from the MAUDE database	3
p53 and Ki-67 combined with periodic acid-Schiff staining for the diagnosis of early stage esophageal squamous cell carcinoma lesions in biopsy specimens	3
Nationwide survey of the follow-up practices for patients with esophageal carcinoma after radical treatment: historical changes and future perspectives in Japan	3
Pivotal trial of a biodegradable stent for patients with refractory benign esophageal stricture	3
The relationship between manometric subtype and symptom details in achalasia	3
Deleterious alterations of DNA damage response and repair genes and clinical benefit to anti-PD-1 therapy in esophageal squamous cell carcinoma	3
Essential risk factors for operative mortality in elderly esophageal cancer patients registered in the National Clinical Database of Japan	3
Surgical outcomes and quality of life assessment of esophagectomy for cancer with colon conduit via retrosternal route	3
Microscopic venous invasion is a predictor of prognosis in patients with esophageal squamous cell carcinoma undergoing ineffective neoadjuvant chemotherapy and surgery	3
Complete response to definitive chemoradiotherapy in unresectable locally advanced esophageal squamous cell carcinoma	3
A phase II study of S-1 therapy for patients with advanced and recurrent esophageal cancer resistant or intolerable to fluorouracil, platinum, and taxane therapy (OGSG 1404)	3
Comparison of proton-based definitive chemoradiotherapy and surgery-based therapy for esophageal squamous cell carcinoma: a multi-center retrospective Japanese cohort study	3
Impact of patient position on esophageal motility disorders using high-resolution esophageal manometry with impedance (HREMI): supine versus upright swallows	3
Primary esophageal non-Hodgkin’s lymphoma: demographics, clinical characteristics, histopathologic types, and survival in 179 patients from the SEER program and systematic review of the literature	3
Esophageal cancer practice guidelines 2022 edited by the Japan Esophageal Society: part 2	2
Investigating the synergistic effects of immunochemotherapy in esophageal squamous cell carcinoma	2
The relationship between the esophageal endoscopic submucosal dissection technical difficulty and its intraoperative process	2
Significance of chemotherapy-free interval and tumor regression grade in patients with recurrent esophageal squamous cell carcinoma receiving chemotherapy with fluorouracil and platinum after esophage	2
Continuous cuff pressure control on middle-aged and elderly patients undergoing endoscopic submucosal dissection of the esophagus effect of airway injury	2
Correction: Implication of changes in PD-L1 expression during neoadjuvant chemotherapy with docetaxel, cisplatin, and 5-fluorouracil (DCF) regimen in esophageal squamous cell carcinoma	2
Different gastric tubes in esophageal reconstruction during esophagectomy	2
Manometric esophagogastric junction barrier metrics as predictors of gastroesophageal reflux	2
The implementation status of prehabilitation during neoadjuvant chemotherapy for patients with locally advanced esophageal cancer: a questionnaire survey to the board-certified facilities in Japan	2
Nutritional management during chemotherapy and chemoradiotherapy for advanced esophageal cancer	2
Multimodal deep-learning model using pre-treatment endoscopic images and clinical information to predict efficacy of neoadjuvant chemotherapy in esophageal squamous cell carcinoma	2
Predictors of technical difficulty for trainees in esophageal endoscopic submucosal dissection	2
Systemic inflammation score as a predictor of death within one year after esophagectomy	2
The totally mechanical Collard technique for cervical esophagogastric anastomosis reduces anastomotic stricture compared with triangular anastomosis in minimally invasive esophagectomy with gastric co	2
Usefulness of endoscopic ultrasound in predicting treatment efficacy of salvage endoscopic therapy for local failure after chemoradiotherapy for esophageal squamous cell carcinoma	2
Visceral obesity is associated with an increased risk of developing esophago-gastric junctional adenocarcinoma in Japan: a population-based case–control study in Akita Prefecture	2
Characteristics of multiple esophageal squamous cell carcinomas detected in the surveillance after endoscopic resection	2
An “esophageal rosette” sign is useful for predicting favorable outcomes in peroral endoscopic myotomy for esophageal achalasia	2
First-line pembrolizumab + chemotherapy in Japanese patients with advanced/metastatic esophageal cancer from KEYNOTE-590	2
Fruit and vegetable consumption and risk of esophageal cancer in the Asian region: a systematic review and meta-analysis	2
Correction: Comparison of proton-based Definitive chemoradiotherapy and surgery-based therapy for esophageal squamous cell carcinoma: a multi-center retrospective Japanese cohort study	2
Preoperative evaluation of oral hygiene may predict the overall survival of patients with esophageal cancer	2
Clinicopathological features and prognosis of gastric tube cancer after esophagectomy for esophageal cancer: a nationwide study in Japan	2
High-resolution manometry with additional maneuvers using the Starlet system: normative thresholds and diagnostic yields for relevant esophagogastric junction outflow disorders	2