OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Innate Immunity is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Does ATP via purinergic receptor signalling fuel pulmonary fibrosis?	96
Neutrophils Display Novel Partners of Cytosolic Proliferating Cell Nuclear Antigen Involved in Interferon Response in COVID-19 Patients	84
TLR9 dependent activation by inactivated parapoxvirus ovis (iPPVO) in murine bone marrow-derived dendritic cells is associated with specific strain-dependent dendritic cell subsets	35
Liver X Receptors and Inflammatory-Induced C/EBPβ Selectively Cooperate to Control CD38 Transcription	27
Stat3 Regulates Developmental Hematopoiesis and Impacts Myeloid Cell Function via Canonical and Non-Canonical Modalities	26
Analyzing the Role of Specific Damage-Associated Molecular Patterns-Related Genes in Osteoarthritis and Investigating the Association between β-Amyloid and Apolipoprotein E Isoforms	23
TLR7 Activation in M-CSF-Dependent Monocyte-Derived Human Macrophages Potentiates Inflammatory Responses and Prompts Neutrophil Recruitment	23
MCPIP-1-Mediated Immunosuppression of Neutrophils Exacerbates Acute Bacterial Peritonitis and Liver Injury	20
C-X-C Motif Chemokine Ligand 1 Promotes Colitis by Modulating the Gut Microbiota	19
Human host defence peptide LL-37 suppresses TNFα-mediated matrix metalloproteinases MMP9 and MMP13, in human bronchial epithelial cells	19
Obituary of Prof. Uli Theopold, 1957–2023	18
Histamine Produced by Gram-Negative Bacteria Impairs Neutrophil’s Antimicrobial Response by Engaging the Histamine 2 Receptor	17
Bruton’s Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against <b><i>Klebsiella pneumoniae</i></b>	17
Regulation of TLR10 Expression and Its Role in Chemotaxis of Human Neutrophils	16
Functional Analysis of a Novel Complement C5a Receptor 1-Blocking Monoclonal Antibody	14
YTHDC1-Modified m6A Methylation of Hsa_circ_0102678 Promotes Keratinocyte Inflammation Induced by <i>Cutibacterium acnes</i> Biofilm through Regulating miR-146a/TRAF6 and IRAK1 Axis	14
Single Cell Analysis of the Fate of Injected Oncogenic RasV12 Cells in Adult Wild Type <i>Drosophila</i>	13
Human Ribonuclease 6 Has a Protective Role during Experimental Urinary Tract Infection	12
Expansion of Phenotypically Altered Dendritic Cell Populations in the Small Airways and Alveolar Parenchyma in Patients with Chronic Obstructive Pulmonary Disease	12
Lipidomic Profiling of Bronchoalveolar Lavage Fluid Extracellular Vesicles Indicates Their Involvement in Lipopolysaccharide-Induced Acute Lung Injury	12
TLRs1-10 Protein Expression in Circulating Human White Blood Cells during Bacterial and COVID-19 Infections	12
The roles of innate immune cells in atopic dermatitis	12
Inhibition of WNK Kinases in NK Cells Disrupts Cellular Osmoregulation and Control of Tumor Metastasis	11
Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells	11
TLR2 and NLRP3 Orchestrate Regulatory Roles in Escherichia coli Infection-Induced Septicemia in Mouse Models	11

N6-Methyladenosine (m6A) Modification in Natural Immune Cell-Mediated Inflammatory Diseases	11
Bone Marrow Mesenchymal Stem Cells Release miR-378a-5p-Carried Extracellular Vesicles to Alleviate Rheumatoid Arthritis	10
Selected β-Glucans Act as Immune-Training Agents by Improving Anti-Mycobacterial Activity in Human Macrophages: A Pilot Study	10
TGF-β1 Inhibition of ACE2 Mediated by miRNA Uncovers Novel Mechanism of SARS-CoV-2 Pathogenesis	10
Formyl Peptide Receptor Type 2 Deficiency in Myeloid Cells Amplifies Sepsis-Induced Cardiac Dysfunction	9
<b><i>Candida</i></b> Administration Worsens Neutrophil Extracellular Traps in Renal Ischemia Reperfusion Injury Mice: An Impact of Gut Fungi on Acute Kidney Injury	9
Unraveling the Complex Nexus of Macrophage Metabolism, Periodontitis, and Associated Comorbidities	8
CAPN1 Promotes Pseudomonas aeruginosa-Induced Infection by Interacting with TFEB and Inhibiting Autophagy	8
Serine Protease Networks Mediate Immune Responses in Extra-Embryonic Tissues of Eggs in the Tobacco Hornworm, <b><i>Manduca sexta</i></b>	7
Metabolism Shapes Immune Responses to <i>Staphylococcus aureus</i>	7
Common haplotypes within the chromosome 1q31.3 region determine systemic concentrations of the entire complement factor H protein family	7
Immunothrombosis and Complement Activation Contribute to Disease Severity and Adverse Outcome in COVID-19	7
Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery	7
<b><i>Slc6a13</i></b> Deficiency Attenuates <b><i>Pasteurella multocida</i></b> Infection-Induced Inflammation via Glycine-Inflammasome Signaling	7
The Role of Neutrophil in COVID-19 — Positive or Negative	6
Type I interferon, induced by adenovirus or adenoviral vector infection, regulates the cytokine response to LPS in a macrophage type-specific manner	6
Association of Vitamin D with Severity and Outcome of COVID-19: Clinical and Experimental Evidence	6
AhR Regulates Peptidoglycan-Induced Inflammatory Gene Expression in Human Keratinocytes	6
Acknowledgement to Reviewers	6
Mechanisms and Therapeutic Strategies for MAFLD Targeting TLR4 Signaling Pathways	6
Biomarkers in Chronic Obstructive Pulmonary Disease: Emerging Roles of Eosinophils and Procalcitonin	6
Erratum	6
Tollip Inhibits IL-33 Release and Inflammation in Influenza A Virus-Infected Mouse Airways	6
ESCAPE: An Open-Label Trial of Personalized Immunotherapy in Critically lll COVID-19 Patients	6
The Role of Innate Immune Cells in Nonalcoholic Fatty Liver Disease	6
Metabolic Regulation of Macrophage Activation	5
miR-142-5p Encapsulated by Serum-Derived Extracellular Vesicles Protects against Acute Lung Injury in Septic Rats following Remote Ischemic Preconditioning via the PTEN/PI3K/Akt Axis	5
Human Monocytes Exposed to SARS-CoV-2 Display Features of Innate Immune Memory Producing High Levels of CXCL10 upon Restimulation	5
C4b-Binding Protein and Factor H Attenuate NLRP3 Inflammasome-Mediated Signalling Response during Group A Streptococci Infection in Human Cells	5
Immunometabolism: Where Immunology and Metabolism Meet	5
Innate Immune Response to MPOX Infection: Mechanisms and Immune Escape	5
Combined Heterozygous Genetic Variations in Complement C2 and C8B: An Explanation for Multidimensional Immune Imbalance?	5
Advanced Glycation End Products-Induced Activation of Keratinocytes: A Mechanism Underlying Cutaneous Immune Response in Psoriasis	5
Interactions between Macrophages and Biofilm during <i>Staphylococcus aureus</i>-Associated Implant Infection: Difficulties and Solutions	5
Hydrogen Peroxide Is Crucial for NLRP3 Inflammasome-Mediated IL-1β Production and Cell Death in Pneumococcal Infections of Bronchial Epithelial Cells	5
Tryptophol Acetate and Tyrosol Acetate, Small-Molecule Metabolites Identified in a Probiotic Mixture, Inhibit Hyperinflammation	4
C-Terminal PEGylation Improves SAAP-148 Peptide’s Immunomodulatory Activities	4
The Capsule of <b><i>Acinetobacter baumannii</i></b> Protects against the Innate Immune Response	4
Procoagulant Activity of Blood and Microvesicles Is Disturbed by Pneumococcal Pneumolysin, Which Interacts with Coagulation Factors	4
Immature Brain Cortical Neurons Have Low Transcriptional Competence to Activate Antiviral Defences and Control RNA Virus Infections	4
IRF1 Is Required for MDA5 (IFIH1) Induction by IFN-α, LPS, and poly(I:C) in Murine Macrophages	4
MicroRNA-9-1 Attenuates Influenza A Virus Replication via Targeting Tankyrase 1	4
Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium	4
SP1 Promotes HDAC4 Expression and Inhibits HMGB1 Expression to Reduce Intestinal Barrier Dysfunction, Oxidative Stress, and Inflammatory Response after Sepsis	4
Murine Ribonuclease 6 Limits Bacterial Dissemination During Experimental Urinary Tract Infection	3
Macrophage: Hidden Criminal in Therapy Resistance	3
Unraveling the Intricate Web: Complement Activation Shapes the Pathogenesis of Sepsis-Induced Coagulopathy	3
Increase in the Complement Activation Product C4d and the Terminal Complement Complex sC5b-9 Is Associated with Disease Severity and a Fatal Outcome in Necrotizing Soft-Tissue Infection	3
The inflammatory response induced by Aspergillus fumigatus conidia is dependent on complement activation - Insight from a whole blood model	3
HMGB1-Like Dorsal Switch Protein 1 Triggers a Damage Signal in Mosquito Gut to Activate Dual Oxidase via Eicosanoids	3

Macrophage Evolution during Progression of Hepatitis Virus B-Related Acute-on-Chronic Liver Failure	3
Impaired Degradation of Neutrophil Extracellular Traps: A Possible Severity Factor of Elderly Male COVID-19 Patients	3
Glyceraldehyde-3-Phosphate Dehydrogenase Binds with Spike Protein and Inhibits the Entry of SARS-CoV-2 into Host Cells	3
The Gene Signature of Activated M-CSF-Primed Human Monocyte-Derived Macrophages Is IL-10-Dependent	3
Innate Immune Responses to RSV Infection Facilitated by OGG1, an Enzyme Repairing Oxidatively Modified DNA Base Lesions	3
The Citrullination-Neutrophil Extracellular Trap Axis in Chronic Diseases	2
Dectin-1/IL-15 Pathway Affords Protection against Extrapulmonary <i>Aspergillus fumigatus</i> Infection by Regulating Natural Killer Cell Survival	2
Calcineurin Aα Contributes to IgE-Dependent Mast-Cell Mediator Secretion in Allergic Inflammation	2
High Infiltration of CD68<sup>+</sup>/CD163<sup>−</sup> Macrophages Is an Adverse Prognostic Factor after Neoadjuvant Chemotherapy in Esophageal and Gastric Adenocarcinoma	2
Single-nucleus sequencing of silkworm larval brain reveals the key role of lysozyme in the antiviral immune response in brain hemocytes	2
Farewell to Professors Arne Egesten and Heiko Herwald	2
Emerging Roles of cGAS-STING Signaling in Mediating Ocular Inflammation	2
Immunometabolic Regulation of Bacterial Infection, Biofilms, and Antibiotic Susceptibility	2
KDM6A Lysine Demethylase Directs Epigenetic Polarity of MDSCs during Murine Sepsis	2
Interleukin-33 Ameliorates Murine Systemic Lupus Erythematosus and Is Associated with Induction of M2 Macrophage Polarisation and Regulatory T Cells	2
Mitochondrial Damage-Associated Molecular Patterns and Metabolism in the Regulation of Innate Immunity	2
Mast Cell Tryptase Potentiates Neutrophil Extracellular Trap Formation	2