OOIR: Observatory of International Research

Papers

(The median citation count of Journal of Innate Immunity is 3. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Expansion of Phenotypically Altered Dendritic Cell Populations in the Small Airways and Alveolar Parenchyma in Patients with Chronic Obstructive Pulmonary Disease	39
Obituary of Prof. Uli Theopold, 1957–2023	32
Regulation of TLR10 Expression and Its Role in Chemotaxis of Human Neutrophils	26
Human Ribonuclease 6 Has a Protective Role during Experimental Urinary Tract Infection	25
Compartment-Specific NK Cell Phenotypes Reveal Distinct Maturation and Activation States in Inflammatory Arthritis	24
Type I interferon, induced by adenovirus or adenoviral vector infection, regulates the cytokine response to LPS in a macrophage type-specific manner	23
Metabolism Shapes Immune Responses to <i>Staphylococcus aureus</i>	21
Mechanisms and Therapeutic Strategies for MAFLD Targeting TLR4 Signaling Pathways	19
Murine Ribonuclease 6 Limits Bacterial Dissemination During Experimental Urinary Tract Infection	19
Characterization of the Cellular Immune Response to Group B Streptococcal Vaginal Colonization	18
Differential Recognition of Lipopolysaccharide O-Antigens by the Pattern Recognition Molecules Mannan-Binding Lectin and Ficolins of the Complement System	18
<i>Ehrlichia chaffeensis</i> Co-Opts Phagocytic Hemocytes for Systemic Dissemination in the Lone Star Tick, <i>Amblyomma americanum</i>	17
Human Blood Non-Classical/Classical Monocyte Cells Are Heterogeneously Presented in Severe COVID-19 and Correlate with Disease Activity	17
Farewell to Professors Arne Egesten and Heiko Herwald	17
Prior exposure of airway epithelial cells to mycobacteria reduces subsequent Mycobacterium tuberculosis infection and resulting inflammation	16
Pro-Inflammatory of PRDM1/SIRT2/NLRP3 Axis in Monosodium Urate-Induced Acute Gouty Arthritis	15
Streptococcus pyogenes Activates Human Platelets via Streptolysin S-Mediated Calcium Ion Influx	15
The Role of Ficolins in Lung Injury	15
<b><i>Streptococcus pneumoniae</i></b> Impairs Maturation of Human Dendritic Cells and Consequent Activation of CD4<sup>+</sup> T Cells via Pneumolysin	14
Acknowledgement to Reviewers	14
Perilipin 1 Deficiency Prompts Lipolysis in Lipid Droplets and Aggravates the Pathogenesis of Persistent Immune Activation in <i>Drosophila</i>	14
Complex Thrombo-Inflammatory Responses versus Outcomes of Non-COVID-19 Community-Acquired Pneumonia and COVID-19	13
YTHDC1-Modified m6A Methylation of Hsa_circ_0102678 Promotes Keratinocyte Inflammation Induced by <i>Cutibacterium acnes</i> Biofilm through Regulating miR-146a/TRAF6 and IRAK1 Axis	12
GDF15 Suppresses Lymphoproliferation and Humoral Autoimmunity in a Murine Model of Systemic Lupus Erythematosus	12
CLIPA7 Exhibits Pleiotropic Roles in the <b><i>Anopheles gambiae</i></b> Immune Response	12

N6-Methyladenosine (m6A) Modification in Natural Immune Cell-Mediated Inflammatory Diseases	12
The Role of Neutrophil in COVID-19 — Positive or Negative	12
Lipoteichoic Acids Are Essential for Pneumococcal Colonization and Membrane Integrity	12
The Role of Interleukin-1 Receptor-Associated Kinase M in Pulmonary Diseases: Mechanisms and Therapeutic Implications	11
Tollip Inhibits IL-33 Release and Inflammation in Influenza A Virus-Infected Mouse Airways	11
Target-Based Biofilm Inhibition and Antibiotic Enhancement Strategy by MiR.101.3p Using DNA Tetrahedrons	11
miR-142-5p Encapsulated by Serum-Derived Extracellular Vesicles Protects against Acute Lung Injury in Septic Rats following Remote Ischemic Preconditioning via the PTEN/PI3K/Akt Axis	11
IRF1 Is Required for MDA5 (IFIH1) Induction by IFN-α, LPS, and poly(I:C) in Murine Macrophages	10
Development and Characterization of Novel ELISAs for the Specific Quantification of the Factor H-Related Proteins 2, 3, 4, and 5	10
Combined Heterozygous Genetic Variations in Complement C2 and C8B: An Explanation for Multidimensional Immune Imbalance?	10
Unraveling the Complex Nexus of Macrophage Metabolism, Periodontitis, and Associated Comorbidities	10
Interleukin-33 Ameliorates Murine Systemic Lupus Erythematosus and Is Associated with Induction of M2 Macrophage Polarisation and Regulatory T Cells	10
Glyceraldehyde-3-Phosphate Dehydrogenase Binds with Spike Protein and Inhibits the Entry of SARS-CoV-2 into Host Cells	10
TLR10: An intriguing Toll-like receptor with many unanswered questions	10
The Novel Inducer of Innate Immunity HO53 Stimulates Autophagy in Human Airway Epithelial Cells	9
Ste20-Like Kinase TAOK1 Positively Regulates Antiviral Responses by Controlling the TBK1-IRF3 Signaling Axis	9
Acinetobacter baumannii Clinical Isolates Resist Complement-Mediated Lysis by Inhibiting the Complement Cascade and Improperly Depositing MAC	9
Interference with Lipoprotein Maturation Sensitizes Methicillin-Resistant <b><i>Staphylococcus aureus</i></b> to Human Group IIA-Secreted Phospholipase A<sub>2</sub>	9
Erratum	9
Oxidative Stress and Chronic Inflammation as Partners in Crime in Interstitial Cystitis/Bladder Pain Syndrome	9
Dysregulation of TLR Signaling-Associated Gene Expression in X-linked Agammaglobulinemia: Implications for Correlations Genotype-Phenotype and Disease Expression	9
Interactions of Probiotics with the Immune Cells of Patients with COVID-19 Pneumonia	9
Development, Characterization, and in vivo Validation of a Humanized C6 Monoclonal Antibody that Inhibits the Membrane Attack Complex	9
Patients Hospitalized with COVID-19 Demonstrate Distinct Plasma Cytokine and Chemokine Concentrations in vivo and TLR-Mediated Cytokine and Chemokine Production in Whole Blood in vitro	8
Analyzing the Role of Specific Damage-Associated Molecular Patterns-Related Genes in Osteoarthritis and Investigating the Association between β-Amyloid and Apolipoprotein E Isoforms	8
<b><i>Candida</i></b> Administration Worsens Neutrophil Extracellular Traps in Renal Ischemia Reperfusion Injury Mice: An Impact of Gut Fungi on Acute Kidney Injury	8
Does Adenosine Triphosphate via Purinergic Receptor Signalling Fuel Pulmonary Fibrosis?	8
Cathelicidins Induce Toll-Interacting Protein Synthesis to Prevent Apoptosis in Colonic Epithelium	7
Impact of Adenosine Triphosphate Synthase Subunit β on TLR Signaling Pathway in Promoting Airway Remodeling and Heterogeneity of Small Airway Epithelial Cells in Chronic Obstructive Pulmonary Disease	7
Tryptophol Acetate and Tyrosol Acetate, Small-Molecule Metabolites Identified in a Probiotic Mixture, Inhibit Hyperinflammation	7
C4b-Binding Protein and Factor H Attenuate NLRP3 Inflammasome-Mediated Signalling Response during Group A Streptococci Infection in Human Cells	7
Procoagulant Activity of Blood and Microvesicles Is Disturbed by Pneumococcal Pneumolysin, Which Interacts with Coagulation Factors	7
CAPN1 Promotes Pseudomonas aeruginosa-Induced Infection by Interacting with TFEB and Inhibiting Autophagy	7
Impact of Changes in Human Airway Epithelial Cellular Composition and Differentiation on SARS-CoV-2 Infection Biology	6
TLR2 or TLR4 Stimulation Induces Transmembrane TNF-Driven Priming in Macrophages Which Results in Improved Clearance of a Subsequent Staphylococcus aureus Infection	6
C-Terminal PEGylation Improves SAAP-148 Peptide’s Immunomodulatory Activities	6
Degradation of Ubiquitin-Editing Enzyme A20 following Autophagy Activation Promotes RNF168 Nuclear Translocation and NF-κB Activation in Lupus Nephritis	6
Lectin Pathway Enzyme MASP-2 and Downstream Complement Activation in COVID-19	6
Identification of Immune Candidate Genes in Post-Sepsis Syndrome: Linking Innate Immunity to Long-Term Autoimmune Responses	6
Emerging Roles of cGAS-STING Signaling in Mediating Ocular Inflammation	6
RNA Viruses, Toll-Like Receptors, and Cytokines: The Perfect Storm?	6
Ras-Related Protein Rab5a Regulates Complement C5a Receptor Trafficking, Chemotaxis, and Chemokine Secretion in Human Macrophages	5
Pattern-Recognition Receptors and Immunometabolic Reprogramming: What We Know and What to Explore	5
Ex vivo and in vitro Monocyte Responses Do Not Reflect in vivo Immune Responses and Tolerance	5
Role of Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in inflammation and pathogen-associated interactions	5
Development of a C3 Humanized Rat as a New Model for Evaluating Novel C3 Inhibitors	5
Prediction of Respiratory Failure and Mortality in COVID-19 Patients Using Long Pentraxin PTX3	4
TLR9 dependent activation by inactivated parapoxvirus ovis (iPPVO) in murine bone marrow-derived dendritic cells is associated with specific strain-dependent dendritic cell subsets	4
Formyl Peptide Receptor Type 2 Deficiency in Myeloid Cells Amplifies Sepsis-Induced Cardiac Dysfunction	4
Mesenchymal Stromal Cells Facilitate Neutrophil-Trained Immunity by Reprogramming Hematopoietic Stem Cells	4

Stat3 Regulates Developmental Hematopoiesis and Impacts Myeloid Cell Function via Canonical and Non-Canonical Modalities	4
Bruton’s Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against <b><i>Klebsiella pneumoniae</i></b>	4
TLR7 Activation in M-CSF-Dependent Monocyte-Derived Human Macrophages Potentiates Inflammatory Responses and Prompts Neutrophil Recruitment	4
Acknowledgement to Reviewers	4
Histamine Produced by Gram-Negative Bacteria Impairs Neutrophil’s Antimicrobial Response by Engaging the Histamine 2 Receptor	4
TLR2 and NLRP3 Orchestrate Regulatory Roles in Escherichia coli Infection-Induced Septicemia in Mouse Models	4
Acknowledgement to Reviewers	4
Erratum	3
HMGB1-Like Dorsal Switch Protein 1 Triggers a Damage Signal in Mosquito Gut to Activate Dual Oxidase via Eicosanoids	3
Association of Vitamin D with Severity and Outcome of COVID-19: Clinical and Experimental Evidence	3
Circulating Plasmacytoid Dendritic Cells Are Numerically and Functionally Deficient in Trauma Patients	3
Human Monocytes Exposed to SARS-CoV-2 Display Features of Innate Immune Memory Producing High Levels of CXCL10 upon Restimulation	3
Innate Immune Responses to RSV Infection Facilitated by OGG1, an Enzyme Repairing Oxidatively Modified DNA Base Lesions	3
Interaction between Group 3 Innate Lymphoid Cells, Microbiota, and Intestinal Diseases: Mechanisms and Therapeutic Potential	3
The inflammatory response induced by Aspergillus fumigatus conidia is dependent on complement activation - Insight from a whole blood model	3
MicroRNA-9-1 Attenuates Influenza A Virus Replication via Targeting Tankyrase 1	3
Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery	3