OOIR: Observatory of International Research

Papers

(The median citation count of Frontiers in Synaptic Neuroscience is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Towards a Comprehensive Optical Connectome at Single Synapse Resolution via Expansion Microscopy	98
Editorial: Brain serotonergic system	91
Neurexins and their ligands at inhibitory synapses	47
Glucagon-like peptide 1 and glucose-dependent insulinotropic peptide hormones and novel receptor agonists protect synapses in Alzheimer’s and Parkinson’s diseases	45
Editorial: Subcellular computations and information processing	44
Synaptic spinules are reliable indicators of excitatory presynaptic bouton size and strength and are ubiquitous components of excitatory synapses in CA1 hippocampus	41
cAMP-Dependent Synaptic Plasticity at the Hippocampal Mossy Fiber Terminal	41
Memory retrieval, reconsolidation, and extinction: Exploring the boundary conditions of post-conditioning cue exposure	40
Organization of Presynaptic Autophagy-Related Processes	35
Correlative Live-Cell and Super-Resolution Imaging to Link Presynaptic Molecular Organisation With Function	34
High-Resolution Fluorescence Imaging Combined With Computer Simulations to Quantitate Surface Dynamics and Nanoscale Organization of Neuroligin-1 at Synapses	34
The Wingless planar cell polarity pathway is essential for optimal activity-dependent synaptic plasticity	33
Triose-phosphate isomerase deficiency is associated with a dysregulation of synaptic vesicle recycling in Drosophila melanogaster	33
Editorial: Role of protein palmitoylation in synaptic plasticity and neuronal differentiation, volume II	32
Heightened sympathetic neuron activity and altered cardiomyocyte properties in spontaneously hypertensive rats during the postnatal period	32
Editorial: The synaptic basis of neuropathology	31
Editorial: Synaptic plasticity and dysfunction, friend or foe?	28
Age-Specific Modulation of Prefrontal Cortex LTP by Glucocorticoid Receptors Following Brief Exposure to HFD	28
Parvalbumin Interneurons and Perineuronal Nets in the Hippocampus and Retrosplenial Cortex of Adult Male Mice After Early Social Isolation Stress and Perinatal NMDA Receptor Antagonist Treatment	28
β-adrenergic receptor-induced E-S potentiation in the dorsal and ventral hippocampus	26
Pharmacological and Biophysical Characteristics of Picrotoxin-Resistant, δSubunit-Containing GABAA Receptors	21
(M)Unc13s in Active Zone Diversity: A Drosophila Perspective	21
Editorial: The Emerging Role of Endocannabinoids in Synaptic Plasticity, Reward, and Addiction	20
Regulation of Inhibitory Signaling at the Receptor and Cellular Level; Advances in Our Understanding of GABAergic Neurotransmission and the Mechanisms by Which It Is Disrupted in Epilepsy	20
Cryo-EM tomography and automatic segmentation delineate modular structures in the postsynaptic density	17

Differential modulation of collybistin conformational dynamics by the closely related GTPases Cdc42 and TC10	16
Killer or helper? The mechanism underlying the role of adenylate activated kinase in sound conditioning	16
Editorial: Synaptopathies: from bench to bedside	16
Cyclic AMP response element-binding protein (CREB) transcription factor in astrocytic synaptic communication	16
Editorial: Perineuronal Nets as Therapeutic Targets for the Treatment of Neuropsychiatric Disorders	15
Editorial: Plasticity of inhibitory cells in health and disease	15
Synaptic Density and Neuronal Metabolic Function Measured by Positron Emission Tomography in the Unilateral 6-OHDA Rat Model of Parkinson’s Disease	15
The effect of single-cell knockout of Fragile X Messenger Ribonucleoprotein on synaptic structural plasticity	14
Editorial: Activated Synapses	13
Cell-autonomous and differential endocannabinoid signaling impacts the development of presynaptic retinal ganglion cell axon connectivity in vivo	13
Different Synaptic Plasticity After Physiological and Psychological Stress in the Anterior Insular Cortex in an Observational Fear Mouse Model	13
Dentate Granule Cells Are Hyperexcitable in the TgF344-AD Rat Model of Alzheimer's Disease	12
Chemical Imaging and Analysis of Single Nerve Cells by Secondary Ion Mass Spectrometry Imaging and Cellular Electrochemistry	12
Presynaptic Mitochondria Communicate With Release Sites for Spatio-Temporal Regulation of Exocytosis at the Motor Nerve Terminal	12
Cellular basis of learning and memory in the carotid body	12
Editorial: Insights in synaptic neuroscience 2022	12
Resilient Hippocampal Gamma Rhythmogenesis and Parvalbumin-Expressing Interneuron Function Before and After Plaque Burden in 5xFAD Alzheimer’s Disease Model	11
Recording plasticity in neuronal activity in the rodent intrinsic cardiac nervous system using calcium imaging techniques	11
Contribution of Membrane Lipids to Postsynaptic Protein Organization	11
High frequency stimulation activates hot spots of spontaneous synaptic transmission	11
Palmitoylation of A-kinase anchoring protein 79/150 modulates its nanoscale organization, trafficking, and mobility in postsynaptic spines	10
Synaptic plasticity through a naturalistic lens	10
SHANK3 Antibody Validation: Differential Performance in Western Blotting, Immunocyto- and Immunohistochemistry	10
rTg(TauP301L)4510 mice exhibit increased VGlut1 in hippocampal presynaptic glutamatergic vesicles and increased extracellular glutamate release	10
Transsynaptic Long-Term Potentiation in the Hippocampus of Behaving Mice	10
Intracellular Properties of Deep-Layer Pyramidal Neurons in Frontal Eye Field of Macaque Monkeys	9
Rapid sequential clustering of NMDARs, CaMKII, and AMPARs upon activation of NMDARs at developing synapses	9
Bringing synapses into focus: Recent advances in synaptic imaging and mass-spectrometry for studying synaptopathy	9
Room for Two: The Synaptophysin/Synaptobrevin Complex	9
Age-related changes in olivocochlear efferent innervation in gerbils	8
Light Sheet Illumination for 3D Single-Molecule Super-Resolution Imaging of Neuronal Synapses	8
Enhanced Non-Associative Long-Term Potentiation in Immature Granule Cells in the Dentate Gyrus of Adult Rats	8
Protein phosphatase-1 inhibitor-2 promotes PP1γ positive regulation of synaptic transmission	8
Rethinking the network determinants of motor disability in Parkinson’s disease	8
Jacob, a Synapto-Nuclear Protein Messenger Linking N-methyl-D-aspartate Receptor Activation to Nuclear Gene Expression	7
Dynamics of Neuromuscular Transmission Reproduced by Calcium-Dependent and Reversible Serial Transitions in the Vesicle Fusion Complex	7
Distinctive biophysical features of human cell-types: insights from studies of neurosurgically resected brain tissue	7
Editorial: Structural and quantitative modeling of synapses	7
Serotonin as a volume transmission signal in the “simple nervous system” of mollusks: From axonal guidance to behavioral orchestration	7
Cellular Strategies for Frequency-Dependent Computation of Interaural Time Difference	7
Hearing Loss Increases Inhibitory Effects of Prefrontal Cortex Stimulation on Sound Evoked Activity in Medial Geniculate Nucleus	7
Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity	6
Cell-Type-Specific Adaptions in Striatal Medium-Sized Spiny Neurons and Their Roles in Behavioral Responses to Drugs of Abuse	6
Unraveling Functional Diversity of Cortical Synaptic Architecture Through the Lens of Population Coding	6
Astrocyte: A Foe or a Friend in Intellectual Disability-Related Diseases	6
A novel peptide inhibitor of TRPM2 channels improves recovery of memory function following traumatic brain injury	6
Palmitoylation-regulated interactions of the pseudokinase calmodulin kinase-like vesicle-associated with membranes and Arc/Arg3.1	6
mGluR-dependent plasticity in rodent models of Alzheimer’s disease	6
A Quantitative Perspective of Alpha-Synuclein Dynamics – Why Numbers Matter	5
The Yin and Yang of GABAergic and Glutamatergic Synaptic Plasticity: Opposites in Balance by Crosstalking Mechanisms	5

Molecular mechanisms of synaptogenesis	5
GRIN2B-related neurodevelopmental disorder: current understanding of pathophysiological mechanisms	5
Complementary Use of Super-Resolution Imaging Modalities to Study the Nanoscale Architecture of Inhibitory Synapses	5
Hypothesis Relating the Structure, Biochemistry and Function of Active Zone Material Macromolecules at a Neuromuscular Junction	5
Dexmedetomidine and Ketamine Attenuated Neuropathic Pain Related Behaviors via STING Pathway to Induce ER-Phagy	5
The Shaping of AMPA Receptor Surface Distribution by Neuronal Activity	5
A tribute to Dr. Akira Yoshii, MD, PhD	5
Roles of AMPA receptors in social behaviors	5
Diverse organization of voltage-gated calcium channels at presynaptic active zones	5
Nano-Organization at the Synapse: Segregation of Distinct Forms of Neurotransmission	5
Mechanisms Underlying Mu Opioid Receptor Effects on Parallel Fiber-Purkinje Cell Synaptic Transmission in Mouse Cerebellar Cortex	5
Corrigendum: Correlative Live-Cell and Super-Resolution Imaging to Link Presynaptic Molecular Organisation With Function	5