OOIR: Observatory of International Research

Papers

(The median citation count of Frontiers in Synaptic Neuroscience is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Synaptic spinules are reliable indicators of excitatory presynaptic bouton size and strength and are ubiquitous components of excitatory synapses in CA1 hippocampus	110
Editorial: Subcellular computations and information processing	101
Neurexins and their ligands at inhibitory synapses	49
Towards a Comprehensive Optical Connectome at Single Synapse Resolution via Expansion Microscopy	47
Exploring the singularity of human neurons: keep calm and carry on	46
Glucagon-like peptide 1 and glucose-dependent insulinotropic peptide hormones and novel receptor agonists protect synapses in Alzheimer’s and Parkinson’s diseases	45
cAMP-Dependent Synaptic Plasticity at the Hippocampal Mossy Fiber Terminal	43
Editorial: Brain serotonergic system	40
Organization of Presynaptic Autophagy-Related Processes	38
Memory retrieval, reconsolidation, and extinction: Exploring the boundary conditions of post-conditioning cue exposure	37
Correlative Live-Cell and Super-Resolution Imaging to Link Presynaptic Molecular Organisation With Function	36
The Wingless planar cell polarity pathway is essential for optimal activity-dependent synaptic plasticity	34
High-Resolution Fluorescence Imaging Combined With Computer Simulations to Quantitate Surface Dynamics and Nanoscale Organization of Neuroligin-1 at Synapses	34
Triose-phosphate isomerase deficiency is associated with a dysregulation of synaptic vesicle recycling in Drosophila melanogaster	34
Heightened sympathetic neuron activity and altered cardiomyocyte properties in spontaneously hypertensive rats during the postnatal period	34
Editorial: Role of protein palmitoylation in synaptic plasticity and neuronal differentiation, volume II	33
Editorial: The synaptic basis of neuropathology	32
β-adrenergic receptor-induced E-S potentiation in the dorsal and ventral hippocampus	31
Editorial: Synaptic plasticity and dysfunction, friend or foe?	27
Pharmacological and Biophysical Characteristics of Picrotoxin-Resistant, δSubunit-Containing GABAA Receptors	23
(M)Unc13s in Active Zone Diversity: A Drosophila Perspective	21
Editorial: The Emerging Role of Endocannabinoids in Synaptic Plasticity, Reward, and Addiction	20
Cryo-EM tomography and automatic segmentation delineate modular structures in the postsynaptic density	18
Regulation of Inhibitory Signaling at the Receptor and Cellular Level; Advances in Our Understanding of GABAergic Neurotransmission and the Mechanisms by Which It Is Disrupted in Epilepsy	18
Differential modulation of collybistin conformational dynamics by the closely related GTPases Cdc42 and TC10	17

Cyclic AMP response element-binding protein (CREB) transcription factor in astrocytic synaptic communication	17
Editorial: Synaptopathies: from bench to bedside	15
Killer or helper? The mechanism underlying the role of adenylate activated kinase in sound conditioning	15
Synaptic Density and Neuronal Metabolic Function Measured by Positron Emission Tomography in the Unilateral 6-OHDA Rat Model of Parkinson’s Disease	15
Editorial: Plasticity of inhibitory cells in health and disease	15
Editorial: Activated Synapses	14
Editorial: Perineuronal Nets as Therapeutic Targets for the Treatment of Neuropsychiatric Disorders	13
Editorial: Insights in synaptic neuroscience 2022	13
Cell-autonomous and differential endocannabinoid signaling impacts the development of presynaptic retinal ganglion cell axon connectivity in vivo	13
The effect of single-cell knockout of Fragile X Messenger Ribonucleoprotein on synaptic structural plasticity	13
Different Synaptic Plasticity After Physiological and Psychological Stress in the Anterior Insular Cortex in an Observational Fear Mouse Model	13
Chemical Imaging and Analysis of Single Nerve Cells by Secondary Ion Mass Spectrometry Imaging and Cellular Electrochemistry	12
Presynaptic Mitochondria Communicate With Release Sites for Spatio-Temporal Regulation of Exocytosis at the Motor Nerve Terminal	12
Recording plasticity in neuronal activity in the rodent intrinsic cardiac nervous system using calcium imaging techniques	12
Dentate Granule Cells Are Hyperexcitable in the TgF344-AD Rat Model of Alzheimer's Disease	12
High frequency stimulation activates hot spots of spontaneous synaptic transmission	12
Cellular basis of learning and memory in the carotid body	11
Resilient Hippocampal Gamma Rhythmogenesis and Parvalbumin-Expressing Interneuron Function Before and After Plaque Burden in 5xFAD Alzheimer’s Disease Model	11
Transsynaptic Long-Term Potentiation in the Hippocampus of Behaving Mice	11
Palmitoylation of A-kinase anchoring protein 79/150 modulates its nanoscale organization, trafficking, and mobility in postsynaptic spines	11
SHANK3 Antibody Validation: Differential Performance in Western Blotting, Immunocyto- and Immunohistochemistry	10
Synaptic plasticity through a naturalistic lens	10
rTg(TauP301L)4510 mice exhibit increased VGlut1 in hippocampal presynaptic glutamatergic vesicles and increased extracellular glutamate release	10
Rapid sequential clustering of NMDARs, CaMKII, and AMPARs upon activation of NMDARs at developing synapses	9
Contribution of Membrane Lipids to Postsynaptic Protein Organization	9
Serotonin as a volume transmission signal in the “simple nervous system” of mollusks: From axonal guidance to behavioral orchestration	9
AMPA receptors in the evolving synapse: structure, function, and disease implications	9
Bringing synapses into focus: Recent advances in synaptic imaging and mass-spectrometry for studying synaptopathy	8
Enhanced Non-Associative Long-Term Potentiation in Immature Granule Cells in the Dentate Gyrus of Adult Rats	8
Protein phosphatase-1 inhibitor-2 promotes PP1γ positive regulation of synaptic transmission	8
Dynamics of Neuromuscular Transmission Reproduced by Calcium-Dependent and Reversible Serial Transitions in the Vesicle Fusion Complex	8
Rethinking the network determinants of motor disability in Parkinson’s disease	8
Age-related changes in olivocochlear efferent innervation in gerbils	8
Light Sheet Illumination for 3D Single-Molecule Super-Resolution Imaging of Neuronal Synapses	8
Jacob, a Synapto-Nuclear Protein Messenger Linking N-methyl-D-aspartate Receptor Activation to Nuclear Gene Expression	7
Is it possible to prevent excessive synaptic pruning in schizophrenia? Possibilities and limitations	7
Editorial: Structural and quantitative modeling of synapses	7
Cell-Type-Specific Adaptions in Striatal Medium-Sized Spiny Neurons and Their Roles in Behavioral Responses to Drugs of Abuse	7
Cellular Strategies for Frequency-Dependent Computation of Interaural Time Difference	7
Distinctive biophysical features of human cell-types: insights from studies of neurosurgically resected brain tissue	7
Astrocyte: A Foe or a Friend in Intellectual Disability-Related Diseases	6
Roles of AMPA receptors in social behaviors	6
Diverse organization of voltage-gated calcium channels at presynaptic active zones	6
Hearing Loss Increases Inhibitory Effects of Prefrontal Cortex Stimulation on Sound Evoked Activity in Medial Geniculate Nucleus	6
Unraveling Functional Diversity of Cortical Synaptic Architecture Through the Lens of Population Coding	6
Hypothesis Relating the Structure, Biochemistry and Function of Active Zone Material Macromolecules at a Neuromuscular Junction	6
Palmitoylation-regulated interactions of the pseudokinase calmodulin kinase-like vesicle-associated with membranes and Arc/Arg3.1	6
A novel peptide inhibitor of TRPM2 channels improves recovery of memory function following traumatic brain injury	6
mGluR-dependent plasticity in rodent models of Alzheimer’s disease	6
Complementary Use of Super-Resolution Imaging Modalities to Study the Nanoscale Architecture of Inhibitory Synapses	6

Identification of Synaptic DGKθ Interactors That Stimulate DGKθ Activity	6
GRIN2B-related neurodevelopmental disorder: current understanding of pathophysiological mechanisms	5
Dexmedetomidine and Ketamine Attenuated Neuropathic Pain Related Behaviors via STING Pathway to Induce ER-Phagy	5
Mechanisms Underlying Mu Opioid Receptor Effects on Parallel Fiber-Purkinje Cell Synaptic Transmission in Mouse Cerebellar Cortex	5
Corrigendum: Correlative Live-Cell and Super-Resolution Imaging to Link Presynaptic Molecular Organisation With Function	5
AMPA Receptor Function in Hypothalamic Synapses	5
The Shaping of AMPA Receptor Surface Distribution by Neuronal Activity	5
Molecular mechanisms of synaptogenesis	5
Modification of the synaptic cleft under excitatory conditions	5
Genetic disorders of neurotransmitter release machinery	5
The Yin and Yang of GABAergic and Glutamatergic Synaptic Plasticity: Opposites in Balance by Crosstalking Mechanisms	5
Nano-Organization at the Synapse: Segregation of Distinct Forms of Neurotransmission	5
A tribute to Dr. Akira Yoshii, MD, PhD	5
Visualizing Presynaptic Active Zones and Synaptic Vesicles	5