Frontiers in Pharmacology

Article	Citations
Application of artificial intelligence large language models in drug target discovery	645
Gut microbiome-mediated mechanisms in aging-related diseases: are probiotics ready for prime time?	365
Effect of age and ICU types on mortality in invasive mechanically ventilated patients with sepsis receiving dexmedetomidine: a retrospective cohort study with propensity score matching	330
Experience of a Strategy Including CYP2C19 Preemptive Genotyping Followed by Therapeutic Drug Monitoring of Voriconazole in Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation	327
Correction: The antipsychotics functional index (AFI) in schizophrenia	311
Network Pharmacology–Based Identification of Key Mechanisms of Xihuang Pill in the Treatment of Triple-Negative Breast Cancer Stem Cells	311
CDFA: Calibrated deep feature aggregation for screening synergistic drug combinations	259
Efficacy and safety of sequential immunosuppressive treatment for severe IgA nephropathy: A retrospective study	253
Association of LEPTIN and other inflammatory markers with preeclampsia: A systematic review	200
Pterostilbene Alleviates Cholestasis by Promoting SIRT1 Activity in Hepatocytes and Macrophages	190
Hermansky-Pudlak Syndrome: Identification of Novel Variants in the Genes HPS3, HPS5, and DTNBP1 (HPS-7)	189
Maresin 1 Attenuates Lipopolysaccharide-Induced Acute Kidney Injury via Inhibiting NOX4/ROS/NF-κB Pathway	185
Microbiome Analysis and Pharmacovigilance After Inhaled Glucocorticoid: Oral Dysbiosis With the Isolation of Three Rothia Species and Subsequent Sjögren’s Syndrome	179
Proteomics Study Reveals the Anti-Depressive Mechanisms and the Compatibility Advantage of Chaihu-Shugan-San in a Rat Model of Chronic Unpredictable Mild Stress	176
The Future of Gene Therapy for Transfusion-Dependent Beta-Thalassemia: The Power of the Lentiviral Vector for Genetically Modified Hematopoietic Stem Cells	172
Asthma Therapies on Pulmonary Tuberculosis Pneumonia in Predominant Bronchiectasis–Asthma Combination	167
Comprehensive Analysis of Chemical Structures That Have Been Tested as CFTR Activating Substances in a Publicly Available Database CandActCFTR	163
Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction	159
Inhibition of Gasdermin D-Mediated Pyroptosis Attenuates the Severity of Seizures and Astroglial Damage in Kainic Acid-Induced Epileptic Mice	157
Naoxintong Capsule Alternates Gut Microbiota and Prevents Hyperlipidemia in High-Fat-Diet Fed Rats	153
MicroRNA 449a can Attenuate Protective Effect of Urokinase Against Pulmonary Embolism	149
Effects of the Full Coverage Policy of Essential Medicines on Inequality in Medication Adherence: A Longitudinal Study in Taizhou, China	143
Integrated network pharmacology and experimental analysis unveil multi-targeted effect of 18α- glycyrrhetinic acid against non-small cell lung cancer	141
Centella asiatica Alters Metabolic Pathways Associated With Alzheimer’s Disease in the 5xFAD Mouse Model of ß-Amyloid Accumulation	132
First-Line ICI Monotherapies for Advanced Non-small-cell Lung Cancer Patients With PD-L1 of at Least 50%: A Cost-Effectiveness Analysis	132

Icotinib derivatives as tyrosine kinase inhibitors with anti-esophageal squamous carcinoma activity	127
Xuanfei Pingchuan Capsules Ameliorate Autophagy in Human Bronchial Epithelial Cells by Inhibiting p38 Phosphorylation	126
Population pharmacokinetics and dosing optimization of unbound teicoplanin in Chinese adult patients	124
Editorial: Dissecting Traditional Medicine via Chemical and Biochemical Techniques: Advanced Analytics and Novel Paradigms	124
The Transcultural Adaptation and Validation of the Chinese Version of the Duke Anticoagulation Satisfaction Scale	124
Corrigendum: Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling	124
Canagliflozin Prevents Lipid Accumulation, Mitochondrial Dysfunction, and Gut Microbiota Dysbiosis in Mice With Diabetic Cardiovascular Disease	123
East Asian Herbal Medicine to Reduce Primary Pain and Adverse Events in Cancer Patients : A Systematic Review and Meta-Analysis With Association Rule Mining to Identify Core Herb Combination	120
Antifungal Drugs and Drug-Induced Liver Injury: A Real-World Study Leveraging the FDA Adverse Event Reporting System Database	118
Wendan decoction in the treatment of nonalcoholic fatty liver disease: A systematic review and meta-analysis	117
Tailoring second-line or above therapy for patients with advanced or metastatic gastric cancer: A multicenter real-world study	115
Cost-effectiveness of empagliflozin for the treatment of heart failure: a systematic review	114
A New Strategy for Multitarget Drug Discovery/Repositioning Through the Identification of Similar 3D Amino Acid Patterns Among Proteins Structures: The Case of Tafluprost and its Effects on Cardiac Io	113
Transcriptome analysis revealed the role of mTOR and MAPK signaling pathways in the white strain of Hypsizygus marmoreus extracts-induced cell death of human hepatoma Hep3B cells	111
Effects of Broussonetia papyrifera (L.) L'Hér. ex Vent. fruits water extract on hippocampal neurogenesis in the treatment of APP/PS1 transgenic mice	111
Associations of Fentanyl, Sufentanil, and Remifentanil With Length of Stay and Mortality Among Mechanically Ventilated Patients: A Registry-Based Cohort Study	110
Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether‐à‐go‐go–Related Gene and Cav1.2	110
Overview of Cannabis including Kampo Medicine and Therapy for Treatment of Dementia: A Review	110
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control	107
The macrocyclic lactone oxacyclododecindione reduces fibrosis progression	107
Appropriateness of Antibiotic Prescriptions in Chinese Primary Health Care and the Impact of the COVID-19 Pandemic: A Typically Descriptive and Longitudinal Database Study in Yinchuan City	106
Title: P2x7 Receptor Activation and Estrogen Status Drive Neuroinflammatory Mechanisms in a Rat Model for Dry Eye	105
Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells	103
Qishen Granule (QSG) Inhibits Monocytes Released From the Spleen and Protect Myocardial Function via the TLR4-MyD88-NF-κB p65 Pathway in Heart Failure Mice	103
Factors influencing plasma concentration of voriconazole and voriconazole- N-oxide in younger adult and elderly patients	101
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood–Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI	101
Cost-effectiveness analysis of lenvatinib plus pembrolizumab compared with chemotherapy for patients with previously treated mismatch repair proficient advanced endometrial cancer in China	101
Editorial: Streaming inflammation: From damage to healing and resilience–Volume II	100
Effect of corticosteroids combined with cyclophosphamide or mycophenolate mofetil therapy for IgA nephropathy with stage 3 or 4 chronic kidney disease: A retrospective cohort study	100
Polygala tenuifolia and Acorus tatarinowii in the treatment of Alzheimer’s disease: a systematic review and meta-analysis	98
Phenotype-Based HPLC-Q-TOF-MS/MS Coupled With Zebrafish Behavior Trajectory Analysis System for the Identification of the Antidepressant Components in Methanol Extract of Anshen Buxin Six Pills	98
Ethnic Diversity and Warfarin Pharmacogenomics	97
Editorial: Pharmacogenetics and pharmacogenomics in Latin America: ethnic variability, new insights in advances and perspectives: a RELIVAF-CYTED initiative, Volume II	94
A minimal PBPK model to accelerate preclinical development of drugs against tuberculosis	94
A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects	93
Antisense Oligonucleotide-Based Therapy on miR-181a-5p Alleviates Cartilage Degradation of Temporomandibular Joint Osteoarthritis via Promoting SIRT1	89
Natural drugs targeting inflammation pathways can be used to treat atherosclerosis	89
Does preterm birth increase the initiation of antidepressant use during the postpartum? A population-based investigation	88
Effects of Dexmedetomidine on Immune Cells: A Narrative Review	87
mPEG-PDLLA Micelles Potentiate Docetaxel for Intraperitoneal Chemotherapy in Ovarian Cancer Peritoneal Metastasis	87
Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity	87
Pharmacokinetics and absorption mechanism of tandospirone citrate	87
Case Report: Rhabdomyolysis secondary to vildagliptin overdose in a suicidal attempt: A case report and brief literature review	86
A Novel Compound, Tanshinol Borneol Ester, Ameliorates Pressure Overload-Induced Cardiac Hypertrophy by Inhibiting Oxidative Stress via the mTOR/β-TrCP/NRF2 Pathway	85
Post-marketing safety surveillance of dalfampridine for multiple sclerosis using FDA adverse event reporting system	84
Network pharmacology and experimental verification-based strategy to explore the underlying mechanism of Liu Jun An Wei formula in the treatment of gastrointestinal reactions caused by chemotherapy fo	84
Hepatoprotective Efficacy and Interventional Mechanism of Qijia Rougan Decoction in Liver Fibrosis	83
Potential mechanisms of Lian-Zhi-Fan solution for TNBS-induced ulcerative colitis in rats via a metabolomics approach	83
Interleukin 22 and its association with neurodegenerative disease activity	82
Molecular determinants of TRPM8 function: key clues for a cool modulation	82

Development of a vaccine against the synthetic opioid U-47700	81
Naoxintong capsule for treating cardiovascular and cerebrovascular diseases: from bench to bedside	81
Interaction and potential mechanisms between atorvastatin and voriconazole, agents used to treat dyslipidemia and fungal infections	81
Title: Understanding a Low Vitamin D State in the Context of COVID-19	80
Integrated analysis of Dendrobium nobile extract Dendrobin A against pancreatic ductal adenocarcinoma based on network pharmacology, bioinformatics, and validation experiments	80
Anticancer effects of OSW-1 on glioma cells via regulation of the PI3K/AKT signal pathway: A network pharmacology approach and experimental validation in vitro and in vivo	79
The Role of Traditional Plant Knowledge in the Fight Against Infectious Diseases: A Meta-Analytic Study in the Catalan Linguistic Area	78
Association between antihypertensive drugs and oral cancer: a drug target Mendelian randomization study	78
Investigation of anti-depression effects and potential mechanisms of the ethyl acetate extract of Cynomorium songaricum Rupr. through the integration of in vivo experiments, LC-MS/MS chemical analysis	76
Research hotspots and trend analysis of cell transplantation in traumatic spinal cord injury: a bibliometric and visualized analysis	75
Mechanism Underlying Acupuncture Therapy in Spinal Cord Injury: A Narrative Overview of Preclinical Studies	75
Gegen Qinlian decoction prevents post-ERCP pancreatitis by regulating NLRP3 inflammasome-mediated pyroptosis	75
The therapeutic potential of natural metabolites in targeting endocrine-independent HER-2-negative breast cancer	75
Emerging Significance of Ginsenosides as Potentially Reversal Agents of Chemoresistance in Cancer Therapy	75
Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway	75
Immune Effect of Active Components of Traditional Chinese Medicine on Triple-Negative Breast Cancer	74
Drug-related problems among transfusion-dependent thalassemia patients: A real-world evidence study	74
Identification of highly effective inhibitors against SARS-CoV-2 main protease: From virtual screening to in vitro study	73
Editorial: Women in nanomedicine	73
Efficacy of Intra-Arterial Plus Intravesical Chemotherapy for High-Risk Non-Muscle-Invasive Bladder Cancer: A Pooled Analysis	72
Baicalein Ameliorates Myocardial Ischemia Through Reduction of Oxidative Stress, Inflammation and Apoptosis via TLR4/MyD88/MAPKS/NF-κB Pathway and Regulation of Ca2+ Homeostasis by L-type Ca2+ Channel	72
Patient-Patient Similarity-Based Screening of a Clinical Data Warehouse to Support Ciliopathy Diagnosis	72
Dioscin Reduces Vascular Damage in the Retina of db/db Mice by Inhibiting the VEGFA Signaling Pathway	71
A Comprehensive Review of BET Protein Biochemistry, Physiology, and Pathological Roles	71
The Protective Effects of Lipid-Lowering Agents on Cardiovascular Disease and Mortality in Maintenance Dialysis Patients: Propensity Score Analysis of a Population-Based Cohort Study	71
Healthcare professional perspectives on medication challenges in the post-stroke patient	71
Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist: In Vitro, Preclinical, and Clinical Data	70
Potential Treat-to-Target Approach for Methamphetamine Use Disorder: A Pilot Study of Adenosine 2A Receptor Antagonist With Positron Emission Tomography	69
Olmesartan Attenuates Single-Lung Ventilation Induced Lung Injury via Regulating Pulmonary Microbiota	69
A Betulinic Acid Derivative, BA5, Induces G0/G1 Cell Arrest, Apoptosis Like-Death, and Morphological Alterations in Leishmania sp	69
The essential role of YAP in ERα36-mediated proliferation and the epithelial-mesenchymal transition in MCF-7 breast cancer cells	69
Corrigendum: Editorial: The mechanisms of action of anti-SARS-CoV-2 drugs	68
Potential targets and applications of nanodrug targeting myeloid cells in osteosarcoma for the enhancement of immunotherapy	68
Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers	68
Natural products from plants and microorganisms: Novel therapeutics for chronic kidney disease via gut microbiota regulation	68
Identification of potential quality markers of Zishen Yutai pill based on spectrum–effect relationship analysis	68
Improvement of solubility, dissolution, and bioavailability of phenytoin intercalated in Mg-Al layered double hydroxide	67
Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation	67
Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models	67
Neuroprotective and Anti-Inflammatory Effect of Pterostilbene Against Cerebral Ischemia/Reperfusion Injury via Suppression of COX-2	66
Ion Channel Dysfunction and Neuroinflammation in Migraine and Depression	66
Screening of Microbial Natural Products and Biological Evaluation of Trichomicin as Potential Anti-Cytokine Storm Agents	66
Machine learning methods for propensity and disease risk score estimation in high-dimensional data: a plasmode simulation and real-world data cohort analysis	66
Fuyuan decoction prevents nasopharyngeal carcinoma metastasis by inhibiting circulating tumor cells/ endothelial cells interplay and enhancing anti-cancer immune response	65
Editorial: Leukocyte biology and muscle pathology: Leukocytes as potential targets to control muscle inflammation, mass, and pain	65
Drug-drug interactions between antithrombotics and direct-acting antivirals in hepatitis C virus (HCV) patients: A brief, updated report	64
Editorial: Evolution of phytochemicals and phytotherapies in the treatment and management of cancer: targeted strategies in cancer precision medicine	64
Investigating the therapeutic potential of hesperidin targeting CRISP2 in intervertebral disc degeneration and cancer risk mitigation	64
The role of l-leucovorin uptake and metabolism in the modulation of 5-fluorouracil efficacy and antifolate toxicity	64
Bibliometric and visualized analysis of sodium–Glucose cotransporter 2 inhibitors	64
Menisoxoisoaporphine A, a novel oxoisoaporphine alkaloid from Menispermi Rhizoma, inhibits inflammation by targeting PDE4B	63
Comparative study of the effects of the three kinds of Kampo-hozai: Ninjinyoeito, Hochuekkito, and Juzentaihoto on anxious and low sociability behavior using NPY-knockout zebrafish	63
Lycium barbarum polysaccharide reverses drug resistance in oxaliplatin-resistant colon cancer cells by inhibiting PI3K/AKT-dependent phosphomannose isomerase	63
Traditional Chinese Medicine targeting the TGF-β/Smad signaling pathway as a potential therapeutic strategy for renal fibrosis	63
Effects of public reporting of prescription indicators on patient choices: evidence from propensity scores matching	62
Function-Wise Dual-Omics analysis for radiation pneumonitis prediction in lung cancer patients	62
The brief overview, antivirus and anti-SARS-CoV-2 activity, quantitative methods, and pharmacokinetics of cepharanthine: a potential small-molecule drug against COVID-19	62
Efficacy of interventions with live combined Bacillus subtilis and Enterococcus faecium enteric-coated capsules in metabolic associated fatty liver disease patients: a meta-analysis of randomized cont	61
Protective effect and mechanism of Qingfei Paidu decoction on myocardial damage mediated by influenza viruses	61
Effects of ranolazine on the arrhythmic substrate in hypertrophic cardiomyopathy	61
Harnessing the power of natural alkaloids: the emergent role in epilepsy therapy	61
Individualized, dynamic, and full-course vancomycin dosing prediction: a study on the customized dose model	61
Editorial: Therapeutic drug monitoring (TDM): a useful tool for pediatric pharmacology applied to routine clinical practice, Volume II	61
pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties	60
D-cycloserine effects on COPD and depression in a murine experimental model	60
Modulating mitochondria with natural extract compounds: from bench to clinical therapeutic opportunities for COPD	60
Quantum chemical calculations of nitrosamine activation and deactivation pathways for carcinogenicity risk assessment	60
Side-stepping the guardian of the genome: current cancer therapeutics targeting mutant p53	60
Exploiting the anti-fibrotic effects of statins on thoracic aortic aneurysm progression: results from a meta-analysis and experimental data	60
Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study	60
Recent clinical evidence on nutrition, novel pharmacotherapy, and vaccination in inflammatory bowel diseases	60
GraphTransNet: predicting epilepsy-related genes using a graph-augmented protein language model	60
Escitalopram oxalate-loaded chitosan nanoparticle in situ gel formulation intended for direct nose-to-brain delivery: in vitro, ex vivo, and in vivo pharmacokinetic evaluation	60
Traditional Chinese medicine in the prevention of diabetes mellitus and cardiovascular complications: mechanisms and therapeutic approaches	59
The electrocardiographic, hemodynamic, echocardiographic, and biochemical evaluation of treatment with edaravone on acute cardiac toxicity of aluminum phosphide	59
Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors	59
Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice	59
Profile of STING agonist and inhibitor research: a bibliometric analysis	59
Effect of Combined Perftoran and Indocyanine Green-Photodynamic Therapy on HypoxamiRs and OncomiRs in Lung Cancer Cells	59
Licorice attenuates cisplatin-induced hepatotoxicity by alleviating endoplasmic reticulum stress and apoptosis	59

Radiosensitization effect of iridium (III) complex on lung cancer cells via mitochondria apoptosis pathway	59
Extracellular vesicles mediate biological information delivery: A double-edged sword in cardiac remodeling after myocardial infarction	59
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps	58
Transcriptome analysis revealed the genes and major pathways involved in prunetrin treated hepatocellular carcinoma cells	58
Androgen receptor inhibitor ameliorates pulmonary arterial hypertension by enhancing the apoptosis level through suppressing the Notch3/Hes5 pathway	58
Evaluation of variable new antigen receptors (vNARs) as a novel cathepsin S (CTSS) targeting strategy	58
Inhibition of retinal neovascularization by Dendrobium polysaccharides: a review	58
Long-term administration of bumetanide improve functional recovery after spinal cord injury in rats	58
Antirheumatoid Arthritic Effects of Sabia parviflora Wall. Leaf Extracts via the NF-κB Pathway and Transient Receptor Potential Protein Family	58
Real-World Evidence Study on the Long-Term Safety of Everolimus in Patients With Tuberous Sclerosis Complex: Final Analysis Results	58
Corrigendum: The Extract of Sonneratia apetala Leaves and Branches Ameliorates Hyperuricemia in Mice by Regulating Renal Uric Acid Transporters and Suppressing the Activation of the JAK/STAT Signaling	58
Differences in right ventricular function and response to targeted therapy between patients with IPAH and PAH-CHD	58
Association between HLA alleles and beta-lactam antibiotics-related severe cutaneous adverse reactions	57
Long-Term Cardiac Damage Associated With Abdominal Irradiation in Mice	57
Several major herb pairs containing Coptidis rhizoma: a review of key traditional uses, constituents and compatibility effects	57
In vitro effect of hydroxychloroquine on pluripotent stem cells and their cardiomyocytes derivatives	57
Paeonol attenuates retinopathy in streptozotocin-induced diabetes in rats by regulating the oxidative stress and polyol pathway	57
Cymensifin A: a promising pharmaceutical candidate to defeat lung cancer via cellular reactive oxygen species-mediated apoptosis	57
Ginsenosides, potential TMPRSS2 inhibitors, a trade-off between the therapeutic combination for anti-PD-1 immunotherapy and the treatment of COVID-19 infection of LUAD patients	57
Effect of herbal medicine Bojungikgi-tang on gut microbiome and symptoms in anorexic patients with atopic dermatitis: a randomized controlled trial	56
Case report: Dezocine’s rapid and sustained antidepressant effects	56
Inhibitory effects of total triterpenoids isolated from the Hedyotis diffusa willd on H1975 cells	56
First-in-human study to assess the safety, tolerability, pharmacokinetics and immunogenicity of DS002, an anti-nerve growth factor monoclonal antibody	56
Research Progress of Chinese Herbal Medicine Intervention in Renal Interstitial Fibrosis	56
Gastrointestinal injury in cardiopulmonary bypass: current insights and future directions	56
Nephroprotective potential of Polyalthia longifolia roots against vancomycin-induced renal toxicity in experimental animals	55
Hemoglobin α-derived peptides VD-hemopressin (α) and RVD-hemopressin (α) are involved in electroacupuncture inhibition of chronic pain	55
Unknown adverse drug reactions from spontaneous reports in a hospital setting: characterization, follow-up, and contribution to the pharmacovigilance system	55
The forensic aspects of suicide and neurotrophin factors: a research study	55
Screening of anti-heart failure active compounds from fangjihuangqi decoction in verapamil-induced zebrafish model by anti-heart failure index approach	55
“Tranq-dope” overdose and mortality: lethality induced by fentanyl and xylazine	55
Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses	55
The synergistic activity of SBC3 in combination with Ebselen against Escherichia coli infection	55
Oxylipins as therapeutic indicators of herbal medicines in cardiovascular diseases: a review	54
The Chinese Herbal Prescription JieZe-1 Inhibits Membrane Fusion and the Toll-like Receptor Signaling Pathway in a Genital Herpes Mouse Model	54
Survival analysis of a 16-year cohort of follicular lymphoma patients receiving systemic treatment in Brazil	54
Clinical study of ganshuang granule combined with tenofovir in the treatment of chronic hepatitis B complicated with nonalcoholic fatty liver disease	54
Role of ferroptosis in atrial fibrillation: a review	54
IgG-like Bispecific Antibody CD3×EpCAM Generated by Split Intein Against Colorectal Cancer	54
Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ25–35	54
An integrative approach to uncover the components, mechanisms, and functions of traditional Chinese medicine prescriptions on male infertility	54
AduCPI2 alleviates MSU-induced acute gouty arthritis in mice by inhibiting cathepsin S and the C5a-C5aR1 axis	53
Editorial: Autoimmune and Inflammatory Rheumatic Diseases: Identifying Biomarkers of Response to Therapy With Biologics	53
Shuxie-1 Decoction Alleviated CUMS -Induced Liver Injury via IL-6/JAK2/STAT3 Signaling	53
Integration of meta-analysis and network pharmacology analysis to investigate the pharmacological mechanisms of traditional Chinese medicine in the treatment of hepatocellular carcinoma	53
RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway	53
Editorial: Utilizing omics strategies to discover new drug targets for cancers	53
The efficacy of polymyxin B in treating stroke-associated pneumonia with carbapenem-resistant Gram-negative bacteria infections: a multicenter real-world study using propensity score matching	53
Impact of domiciliary administration of NSAIDs on COVID-19 hospital outcomes: an unCoVer analysis	53
Ninjin’yoeito ameliorated PPE-induced pulmonary emphysema and anxiety/depressive-like behavior in aged C57BL/6J mice	53
Efficacy and safety profile of biotechnological agents and Janus kinase inhibitors in VEXAS syndrome: data from the international AIDA Network VEXAS registry	52
Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fibrosis	52
Editorial: Methods in predictive toxicology 2023	52
Effects of long-term antipsychotic medication on brain instability in first-episode schizophrenia patients: a resting-state fMRI study	52
Plasma calcitonin gene-related peptide and nitric oxide predict therapeutic response to amlodipine in pediatric primary hypertension	52
Efficacy and safety of Abelmoschus moschatus capsules combined with tripterygium glycoside tablets on diabetic nephropathy: A systematic review and meta-analysis	52
Functional effects of drugs and toxins interacting with NaV1.4	52
Corrigendum: Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling	52
Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata	51
Efficacy and safety of oral minoxidil in the treatment of alopecia: a single-arm rate meta-analysis and systematic review	51
Influence of the ABCB1-rs1045642 gene polymorphism on blood drug concentration in voriconazole-treated patients with severe invasive fungal infection	51
Erratum: Exploring the pharmacological action mechanism of Ligusticum Chuanxiong-Piper Longum couplet medicines on the treatment of migraine based on network pharmacology	51
Chinese herbal compound for multidrug-resistant or extensively drug-resistant bacterial pneumonia: a meta-analysis and trial sequential analysis with association rule mining to identify core herb comb	51
Prediction of Immune-Related Adverse Events Induced by Immune Checkpoint Inhibitors With a Panel of Autoantibodies: Protocol of a Multicenter, Prospective, Observational Cohort Study	51
Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo	51
Strategies for salvage therapy post CAR-T therapy failure in refractory/relapsed multiple myeloma patients	51
Pre-clinical toxicity assessment of Artemisia absinthium extract-loaded polymeric nanoparticles associated with their oral administration	51
Jujuboside B Inhibits the Proliferation of Breast Cancer Cell Lines by Inducing Apoptosis and Autophagy	51
Cytoprotective Effects of Water Soluble Dihydropyrimidinthione Derivative Against UV-B Induced Human Corneal Epithelial Cell Photodamage	51
Water-Soluble Tomato Extract Fruitflow Alters the Phosphoproteomic Profile of Collagen-Stimulated Platelets	50
Pharmacist-Urologist Collaborative Management Improves Clinical Outcomes in Patients With Castration-Resistant Prostate Cancer Receiving Enzalutamide	50
Human matters in asthma: Considering the microbiome in pulmonary health	50
Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data	50
The Amazonian kambô frog Phyllomedusa bicolor (Amphibia: Phyllomedusidae): Current knowledge on biology, phylogeography, toxinology, ethnopharmacology and medical aspects	50
Discovery of novel benzylquinazoline molecules as p97/VCP inhibitors	50
Ginseng and Polygonum multiflorum formula protects brain function in Alzheimer’s disease	49
The functional significance of vascular DNA hypermethylation in atherosclerosis: a historical perspective	49
Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia	49
Editorial: Application of PKPD modeling in drug discovery and development	49
The efficacy of aminosalicylates in acute radiation enteritis: a systematic review and meta-analysis	49
Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-gen	49
Dysregulated neuromodulation in the anterior cingulate cortex in chronic pain	49
Treatment of Poor Sperm Quality and Erectile Dysfunction With Oral Pentoxifylline: A Systematic Review	49
Effect of Fu Zheng Jie Du Formula on outcomes in patients with severe pneumonia receiving prone ventilation: a retrospective cohort study	49
A retrospective analysis of factors associated with the length of hospital stay in COVID-19 patients treated with Nirmatrelvir / Ritonavir	49
Challenges in Treating Genodermatoses: New Therapies at the Horizon	49
Bibliometric analysis of research on retinoic acid in the field of kidney disorders	48
Isatin improves oligoasthenospermia caused by busulfan by regulating GSH/GPX4 axis to inhibit ferroptosis	48
Natural products in treating diabetic kidney disease: a visualized bibliometric analysis	48
The clinically applied PARP inhibitor talazoparib ameliorates imiquimod-induced psoriasis in mice without reducing skin inflammation	48
Potential efficacy and mechanisms of icariin for the animal model of osteonecrosis of the femoral head	48
Economic impact of individualized antimicrobial dose optimization in the critically ill patient in Spain	48
Adverse events in different administration routes of amiodarone: a pharmacovigilance study based on the FDA adverse event reporting system	48
Cost-utility analysis of using paliperidone palmitate in schizophrenia in China	47
Optimizing antidotal treatment with the oral HSP90 inhibitor TAS-116 against hydrochloric acid-induced pulmonary fibrosis in mice	47