Frontiers in Pharmacology

Papers
(The TQCC of Frontiers in Pharmacology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-07-01 to 2026-07-01.)
ArticleCitations
Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study546
pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties368
GraphTransNet: predicting epilepsy-related genes using a graph-augmented protein language model365
Unraveling the pathogenic mechanism of a novel filamin a frameshift variant in periventricular nodular heterotopia324
Quantifying the integrated physiological effects of endothelin-1 on cardiovascular and renal function in healthy subjects: a mathematical modeling analysis316
Editorial: Chronic pain: what is the mechanism?302
Long-term clinical course and outcomes of patients with microscopic polyangiitis-associated interstitial lung disease290
Time trends and regional variations in prices of anticancer medicines in China281
Editorial: Impact of anesthetics on cancer behavior and outcome220
Unlocking cellular traffic jams: olive oil-mediated rescue of CNG mutant channels218
Impact of domiciliary administration of NSAIDs on COVID-19 hospital outcomes: an unCoVer analysis201
Editorial: Methods in predictive toxicology 2023192
Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata188
Differences in right ventricular function and response to targeted therapy between patients with IPAH and PAH-CHD181
Effect of Fu Zheng Jie Du Formula on outcomes in patients with severe pneumonia receiving prone ventilation: a retrospective cohort study177
Case Report: Rhabdomyolysis secondary to vildagliptin overdose in a suicidal attempt: A case report and brief literature review169
Development of a vaccine against the synthetic opioid U-47700169
Potential efficacy and mechanisms of icariin for the animal model of osteonecrosis of the femoral head169
Research hotspots and trend analysis of cell transplantation in traumatic spinal cord injury: a bibliometric and visualized analysis166
Association between antihypertensive drugs and oral cancer: a drug target Mendelian randomization study166
Editorial: Women in nanomedicine157
Editorial: Leukocyte biology and muscle pathology: Leukocytes as potential targets to control muscle inflammation, mass, and pain149
Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers149
Editorial: Evolution of phytochemicals and phytotherapies in the treatment and management of cancer: targeted strategies in cancer precision medicine136
Drug-drug interactions between antithrombotics and direct-acting antivirals in hepatitis C virus (HCV) patients: A brief, updated report130
Non-aromatizable androgens modulate the lipopolysaccharide induced expression of the P2X7 receptor in human adipocytes126
Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma123
Editorial: Advances on targeted nanomedicines for atherosclerosis121
Influence of the ABCB1-rs1045642 gene polymorphism on blood drug concentration in voriconazole-treated patients with severe invasive fungal infection120
A retrospective analysis of factors associated with the length of hospital stay in COVID-19 patients treated with Nirmatrelvir / Ritonavir120
Androgen receptor inhibitor ameliorates pulmonary arterial hypertension by enhancing the apoptosis level through suppressing the Notch3/Hes5 pathway119
Evaluation of variable new antigen receptors (vNARs) as a novel cathepsin S (CTSS) targeting strategy119
Cymensifin A: a promising pharmaceutical candidate to defeat lung cancer via cellular reactive oxygen species-mediated apoptosis118
Case report: Dezocine’s rapid and sustained antidepressant effects117
A Multicenter Study of 239 Patients Aged Over 70 Years With Diffuse Large B-Cell Lymphoma in China116
A nano-preparation approach to enable the delivery of daphnoretin to potentiate the therapeutical efficacy in hepatocellular cancer113
Menisoxoisoaporphine A, a novel oxoisoaporphine alkaloid from Menispermi Rhizoma, inhibits inflammation by targeting PDE4B110
The clinically applied PARP inhibitor talazoparib ameliorates imiquimod-induced psoriasis in mice without reducing skin inflammation109
Male mice treated with combined anti-fibrotic therapeutics, IPW5371 and tadalafil, are predisposed to adverse cardiovascular events108
Which is the optimal choice in lipid-lowering therapy for reducing major cardiovascular events? a network meta-analysis107
The clinical value of screening for acetaminophen in all patients with intentional overdose or altered mental status suspected to be secondary to overdose107
Tailoring second-line or above therapy for patients with advanced or metastatic gastric cancer: A multicenter real-world study106
Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction106
Cost-effectiveness of empagliflozin for the treatment of heart failure: a systematic review104
Editorial: Streaming inflammation: From damage to healing and resilience–Volume II104
The macrocyclic lactone oxacyclododecindione reduces fibrosis progression104
Inhibition of PPARγ by BZ26, a GW9662 derivate, attenuated obesity-related breast cancer progression by inhibiting the reprogramming of mature adipocytes into to cancer associate adipocyte-like cells102
Pharmacokinetics and absorption mechanism of tandospirone citrate101
Commentary: Iridoids derived from Valeriana jatamansi jones alleviates neuroinflammation and blood spinal cord barrier permeability after spinal cord injury by activating the Nrf2/HO-1 signaling pathw100
Natural drugs targeting inflammation pathways can be used to treat atherosclerosis100
Cytotoxicity and reversal effect of sertraline, fluoxetine, and citalopram on MRP1- and MRP7-mediated MDR98
Dopaminergic REST is implicated in the tamoxifen-induced neuroprotection against manganese toxicity in female mice98
Editorial: Genomic discoveries and pharmaceutical development in urologic tumors98
Function-Wise Dual-Omics analysis for radiation pneumonitis prediction in lung cancer patients96
Integrated chemometric evaluation of morphological traits, chemical composition, and hepatotoxicity of Polygonum multiflorum96
Optimization of gabapentin dosage in pediatric patients with renal impairment: a physiologically based pharmacokinetic modeling approach95
Interaction and potential mechanisms between atorvastatin and voriconazole, agents used to treat dyslipidemia and fungal infections94
Icotinib derivatives as tyrosine kinase inhibitors with anti-esophageal squamous carcinoma activity94
Human matters in asthma: Considering the microbiome in pulmonary health94
Ex vivo perfusion model of mouse liver and its application to analyze the effects of OCT1 deficiency94
Neuroregeneration of injured peripheral nerve by fraction B of catfish epidermal secretions through the reversal of the apoptotic pathway and DNA damage94
Evaluation of standard use of intravenous infusion in 25 general hospitals in Shanxi province based on factor analysis and cluster analysis94
Accidental cannabis intoxication in two young children: clinical presentation and toxicokinetics - a case series94
The therapeutic effect of curcumin in metabolic dysfunction-associated steatotic liver disease: a systematic review and meta-analysis of animal studies93
Safety profile of lutein-based blue dyes and surgical lights93
Strategies for salvage therapy post CAR-T therapy failure in refractory/relapsed multiple myeloma patients91
Editorial: Big data for biomedical research of inflammatory diseases91
Protective effects of insulin on dry eye syndrome via TLR4/NF-κB pathway: based on network pharmacology and in vitro experiments validation91
The efficacy of aminosalicylates in acute radiation enteritis: a systematic review and meta-analysis90
Is it possible to diagnose therapeutic adherence in mild cognitive impairment and dementia patients in clinical practice?89
Acute myocardial infarction induced by avatrombopag: a case report89
Functional characterization of the α1-adrenoceptor in adult male rat locus coeruleus neurons ex vivo88
8 specific Chinese herbal injections combined with chemotherapy for breast cancer: a systematic review and network meta-analysis of comparative safety and efficacy87
The Amazonian kambô frog Phyllomedusa bicolor (Amphibia: Phyllomedusidae): Current knowledge on biology, phylogeography, toxinology, ethnopharmacology and medical aspects86
Recent clinical evidence on nutrition, novel pharmacotherapy, and vaccination in inflammatory bowel diseases85
Machine learning methods for propensity and disease risk score estimation in high-dimensional data: a plasmode simulation and real-world data cohort analysis85
Barriers to prescribing and insurance approval of SGLT2 inhibitors for heart failure: a mixed-methods study in Jordan85
Efficacy, safety and mechanism of Honghua Xiaoyao Pill in the treatment of peri-menopausal syndrome: A study protocol for a randomized controlled trial84
Investigating the therapeutic potential of hesperidin targeting CRISP2 in intervertebral disc degeneration and cancer risk mitigation83
Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fibrosis83
A machine learning model integrating gut microbiota biomarkers for predicting neurological recovery after cerebral hypoxia-ischemia: a single-center study augmented with public data83
Doxycycline for the treatment of breast cancer-related lymphedema83
The electrocardiographic, hemodynamic, echocardiographic, and biochemical evaluation of treatment with edaravone on acute cardiac toxicity of aluminum phosphide83
Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells82
Model-informed precision dosing in vancomycin treatment82
Wendan decoction in the treatment of nonalcoholic fatty liver disease: A systematic review and meta-analysis82
Targeting cancer with delphinidin: from molecular insights to therapeutic implications81
T-type calcium channel modulation by hydrogen sulfide in neuropathic pain conditions81
Correction: Efficacy and safety of oral Chinese medicine combined with chemotherapy: a systematic review and network meta-analysis81
A minimal PBPK model to accelerate preclinical development of drugs against tuberculosis80
Sishen Pill and its active phytochemicals in treating inflammatory bowel disease and colon cancer: an overview80
Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III trial80
Potential mechanisms of Lian-Zhi-Fan solution for TNBS-induced ulcerative colitis in rats via a metabolomics approach80
SARS-CoV-2 infection dysregulates the expression of clinically relevant drug metabolizing enzymes in Vero E6 cells and membrane transporters in human lung tissues80
Traditional Chinese medicine in the prevention of diabetes mellitus and cardiovascular complications: mechanisms and therapeutic approaches80
Does preterm birth increase the initiation of antidepressant use during the postpartum? A population-based investigation80
Biomimetic astragaloside-IV-loaded mesoporous silica nanoparticles for treatment of dilated cardiomyopathy79
Exploring the mechanism of baicalein on choroid melanoma based on network pharmacology, transcriptomics and experimental verification79
Circular RNAs in ferroptosis: regulation mechanism and potential clinical application in disease79
Clinical study of ganshuang granule combined with tenofovir in the treatment of chronic hepatitis B complicated with nonalcoholic fatty liver disease78
Effect of age and ICU types on mortality in invasive mechanically ventilated patients with sepsis receiving dexmedetomidine: a retrospective cohort study with propensity score matching77
Case Report: Botulism associated with cosmetic BoNT-A injections: respiratory failure and multidrug-resistant infection as emerging clinical challenges77
Chaihu Longgu Muli Decoction inhibits chronic stress-induced lung cancer epithelial-mesenchymal transition process by suppressing Rap1/ERK signal pathway77
Exploring HSP90α and hs-CRP using AI models to predict prognosis in advanced hepatocellular carcinoma treated with PD-1 inhibitors and targeted therapy77
Chinese herbal compound for multidrug-resistant or extensively drug-resistant bacterial pneumonia: a meta-analysis and trial sequential analysis with association rule mining to identify core herb comb76
Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether‐à‐go‐go–Related Gene and Cav1.276
First-in-human study to assess the safety, tolerability, pharmacokinetics and immunogenicity of DS002, an anti-nerve growth factor monoclonal antibody75
Genome-wide CRISPR screen identified NEK6 as a determinant of sensitivity to CDK4/6 inhibitor in endometrial cancer75
Preventive effect of small molecule active substances on septic cardiomyopathy after abdominal trauma: a systematic review and meta-analysis74
Natural product extracts for ischemic stroke: a methodological evaluation and meta-epidemiological analysis74
A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects74
Correction: The antipsychotics functional index (AFI) in schizophrenia73
Editorial: Metabolic dysfunction-associated fatty liver disease (MAFLD): innovative management strategies using herbal medicines73
Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity73
Effect of herbal medicine Bojungikgi-tang on gut microbiome and symptoms in anorexic patients with atopic dermatitis: a randomized controlled trial73
Corrigendum: Comparison of the effectiveness and safety of perampanel and oxcarbazepine as monotherapy in children and adolescents with newly diagnosed focal epilepsy73
Editorial: Novel therapeutics for urological cancers73
Erratum: Isoflurane-lipid emulsion injection as an anticonvulsant and neuroprotectant treatment for nerve agent exposure72
Inhibitory effects of calcium channel blockers nisoldipine and nimodipine on ivacaftor metabolism and their underlying mechanism72
Corrigendum: Editorial: The mechanisms of action of anti-SARS-CoV-2 drugs72
Corrigendum: Xenon attenuated neonatal lipopolysaccharide exposure induced neuronal necroptosis and subsequently improved cognition in juvenile rats72
Corrigendum: Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling72
Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway71
Erratum: Exploring the pharmacological action mechanism of Ligusticum Chuanxiong-Piper Longum couplet medicines on the treatment of migraine based on network pharmacology71
Pemetrexed sensitizes cisplatin therapy by inducing ferroptosis in NSCLC cells70
Drug-related problems among transfusion-dependent thalassemia patients: A real-world evidence study70
Radiosensitization effect of iridium (III) complex on lung cancer cells via mitochondria apoptosis pathway69
Efficacy analysis of splint combined with platelet-rich plasma in the treatment of temporomandibular joint osteoarthritis69
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control69
Discovery of a novel natural compound, vitekwangin B, with ANO1 protein reduction properties and anticancer potential69
Effect of corticosteroids combined with cyclophosphamide or mycophenolate mofetil therapy for IgA nephropathy with stage 3 or 4 chronic kidney disease: A retrospective cohort study69
Potential of resveratrol in the treatment of interstitial lung disease68
Modulating mitochondria with natural extract compounds: from bench to clinical therapeutic opportunities for COPD68
Natural killer cell-related prognosis signature predicts immune response in colon cancer patients67
Nephroprotective potential of Polyalthia longifolia roots against vancomycin-induced renal toxicity in experimental animals66
Identification of potential quality markers of Zishen Yutai pill based on spectrum–effect relationship analysis66
Long-term administration of bumetanide improve functional recovery after spinal cord injury in rats66
Evaluation of trimetazidine in alleviating paclitaxel-induced peripheral neuropathy in breast cancer patients: a randomized controlled trial66
Efficacy and safety of Chinese medicine injections in combination with docetaxel and cisplatin for non-small cell lung cancer: a network meta-analysis65
Network pharmacology and experimental verification-based strategy to explore the underlying mechanism of Liu Jun An Wei formula in the treatment of gastrointestinal reactions caused by chemotherapy fo65
Gegen Qinlian decoction prevents post-ERCP pancreatitis by regulating NLRP3 inflammasome-mediated pyroptosis65
Using Drosophila melanogaster as a suitable platform for drug discovery from natural products in inflammatory bowel disease65
Efficacy and safety of Abelmoschus moschatus capsules combined with tripterygium glycoside tablets on diabetic nephropathy: A systematic review and meta-analysis65
Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation65
The forensic aspects of suicide and neurotrophin factors: a research study65
Research progress on high-altitude hypoxia pulmonary injury: pathogenesis and Chinese herbal medicine for prevention and treatment64
Population pharmacokinetics and dosing optimization of unbound teicoplanin in Chinese adult patients64
Individualized, dynamic, and full-course vancomycin dosing prediction: a study on the customized dose model64
Ninjin’yoeito ameliorated PPE-induced pulmonary emphysema and anxiety/depressive-like behavior in aged C57BL/6J mice64
Frankincense preparation promotes formation of inflammation-resolving lipid mediators by manipulating lipoxygenases in human innate immune cells64
Evaluation of the efficacy, safety, and economy of nemonoxacin injection versus moxifloxacin injection in the treatment of community-acquired pneumonia64
Editorial: Pharmacogenetics and pharmacogenomics in Latin America: ethnic variability, new insights in advances and perspectives: a RELIVAF-CYTED initiative, Volume II64
Multi-omic analysis reveals that Bacillus licheniformis enhances pekin ducks growth performance via lipid metabolism regulation64
Traditional Chinese Medicine in Treating Primary Podocytosis: From Fundamental Science to Clinical Research64
Challenges in melanoma research and increased melanoma risk call for novel methodological and therapeutic/protective strategies: the case of procyanidin C1 targeting redox metabolism64
Ebracteolata cpd B causes ferroptosis and inhibits progression of lung adenocarcinoma64
Anticancer effects of OSW-1 on glioma cells via regulation of the PI3K/AKT signal pathway: A network pharmacology approach and experimental validation in vitro and in vivo64
Strategy advancements in placental pharmacokinetics: from in vitro experiments to in silico prediction64
Profile of STING agonist and inhibitor research: a bibliometric analysis64
Predicting individual-specific cardiotoxicity responses induced by tyrosine kinase inhibitors63
Restoring redox homeostasis through S-adenosyl-L-methionine and B-vitamins co-supplementation alleviates ethanol induced hepato-pancreatic injury by regulating glutathione biosynthesis in C57BL/6J mic63
Farrerol inhibits proliferation and migration of colorectal cancer via the VEGF signaling pathway: evidence from network pharmacology, molecular docking, molecular dynamics simulation, and in vitro ex63
Functional effects of drugs and toxins interacting with NaV1.463
Xanthine oxidase inhibition by medicinal plants mitigates tenofovir-induced nephrotoxicity: a comprehensive computational and experimental study63
Computational and experimental pharmacology to decode the efficacy of Theobroma cacao L. against doxorubicin-induced organ toxicity in EAC-mediated solid tumor-induced mice63
Retraction: CXCL6 promotes renal interstitial fibrosis in diabetic nephropathy by activating JAK/STAT3 signaling pathway63
Network pharmacology and transcriptomics reveal the mechanisms of FFBZL in the treatment of oral squamous cell carcinoma62
Gastrointestinal injury in cardiopulmonary bypass: current insights and future directions62
Enhancing therapeutic antibody profiling: orthogonal strategies for stability and quality assessment62
LINC01559 drives osimertinib resistance in NSCLC through a ceRNA network regulating miR-320a/IGF2BP3 axis61
Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-gen61
Dexmedetomidine attenuates Alzheimer’s pathogenesis by targeting the ROS-mediated XIAP-MDM2-p53 signaling axis61
Gut microbiota–M cell co-culture in inflammatory bowel disease and its therapeutic potential in organoid platforms61
Pharmacogenomic-guided dosing of fluoropyrimidines beyond DPYD: time for a polygenic algorithm?61
An overview of mechanisms, biomarkers, and treatment strategies for acquired anti-EGFR resistance in RAS wild-type colorectal cancer61
New use of an old drug: mechanism of oseltamivir phosphate inhibiting liver cancer through regulation of lipophagy via NEU161
Efficacy of interventions with live combined Bacillus subtilis and Enterococcus faecium enteric-coated capsules in metabolic associated fatty liver disease patients: a meta-analysis of randomized cont60
The volatile oil of Acorus tatarinowii schott significantly attenuates neuroinflammatory damage in a rat model of tourette syndrome by inhibiting the p38 MAPK/NLRP3/STAT3 signaling pathway60
Advancing the use of real world evidence in health technology assessment: insights from a multi-stakeholder workshop60
Indirect effect of alpha-1-antitrypsin on endotoxin-induced IL-1β secretion from human PBMCs60
The therapeutic potential of Vanilla planifolia: how its phytochemicals combat diabetes?60
Oxylipins as therapeutic indicators of herbal medicines in cardiovascular diseases: a review60
Improvement of solubility, dissolution, and bioavailability of phenytoin intercalated in Mg-Al layered double hydroxide60
Serum metabolomics identifies novel prognostic biomarkers in amanita poisoning59
Multitarget mechanisms of the herb pair Achyranthes bidentata and Paeonia lactiflora Pall. in ameliorating hypertensive cardiomyopathy: combining network pharmacology and functional exploration59
Chrysophanol promotes M2 polarization and inhibits M1 polarization through the NF-κB signaling pathway to attenuate sepsis-associated acute kidney injury59
Correction: Safety and efficacy of tirzepatide in transplant recipients: a systematic review and meta-analysis59
Evaluating a multifaceted stewardship intervention on proton pump inhibitor utilization: an interrupted time-series analysis of prescribing patterns in a northwest Chinese hospital59
Pterostilbene mitigates experimental pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition59
Icariin and related metabolites in fibrosis management: pharmacological properties and molecular mechanism59
Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models59
Editorial: Therapeutic drug monitoring (TDM): a useful tool for pediatric pharmacology applied to routine clinical practice, Volume II58
Healthcare professional perspectives on medication challenges in the post-stroke patient58
Ginsenosides, potential TMPRSS2 inhibitors, a trade-off between the therapeutic combination for anti-PD-1 immunotherapy and the treatment of COVID-19 infection of LUAD patients58
Extracellular vesicles mediate biological information delivery: A double-edged sword in cardiac remodeling after myocardial infarction58
Pharmacogenomics of risperidone in autism spectrum disorder: a minireview58
Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice58
Association of LEPTIN and other inflammatory markers with preeclampsia: A systematic review58
Side-stepping the guardian of the genome: current cancer therapeutics targeting mutant p5358
Several major herb pairs containing Coptidis rhizoma: a review of key traditional uses, constituents and compatibility effects57
Factors influencing plasma concentration of voriconazole and voriconazole- N-oxide in younger adult and elderly patients57
Therapeutic drug monitoring practices of anti-infectives: An Asia-wide cross-sectional survey57
Metabolite-assisted models improve risk prediction of coronary heart disease in patients with diabetes57
Editorial: Oral mucosa and disorders: from drug discovery to development and translation57
The synergistic activity of SBC3 in combination with Ebselen against Escherichia coli infection57
Plasma calcitonin gene-related peptide and nitric oxide predict therapeutic response to amlodipine in pediatric primary hypertension57
IR-780 improves urination function and complications in rats with partial bladder outlet obstruction by protecting bladder smooth muscle cell mitochondria from oxidative stress57
Correction: Editorial: Toxicity mechanisms, exposure, toxicokinetic and risk assessment aspects of metals, toxic for animals and humans, volume III57
Transcriptome analysis revealed the role of mTOR and MAPK signaling pathways in the white strain of Hypsizygus marmoreus extracts-induced cell death of human hepatoma Hep3B cells57
Could peripheral 5-HT level be used as a biomarker for depression diagnosis and treatment? A narrative minireview56
Investigation of anti-depression effects and potential mechanisms of the ethyl acetate extract of Cynomorium songaricum Rupr. through the integration of in vivo experiments, LC-MS/MS chemical analysis56
Genetic characterization of pediatric B-cell acute lymphoblastic leukemia in Argentina uncovers molecular heterogeneity and novel variants56
Effects of Broussonetia papyrifera (L.) L'Hér. ex Vent. fruits water extract on hippocampal neurogenesis in the treatment of APP/PS1 transgenic mice56
The categorizations of vasculogenic mimicry in clear cell renal cell carcinoma unveil inherent connections with clinical and immune features56
Naoxintong capsule for treating cardiovascular and cerebrovascular diseases: from bench to bedside56
Inhibitory effects of total triterpenoids isolated from the Hedyotis diffusa willd on H1975 cells56
Bibliometric and visualized analysis of sodium–Glucose cotransporter 2 inhibitors56
Real-world pharmacovigilance and molecular mechanisms of fruquintinib: SRC and STAT3 as potential off-target mediators of proteinuria55
CDFA: Calibrated deep feature aggregation for screening synergistic drug combinations55
Advances in the study of Ophiopogon japonicus polysaccharides: structural characterization, bioactivity and gut microbiota modulation regulation55
Preventive beneficial effects of cannabidiol in a reserpine-induced progressive model of parkinsonism55
Prescription medication use of United States military service members by therapeutic classification55
Distinct alterations of fecal microbiota refer to the efficacy of adalimumab in Crohn’s disease55
The functional significance of vascular DNA hypermethylation in atherosclerosis: a historical perspective54
Potential role of extracellular granzyme B in wet age-related macular degeneration and fuchs endothelial corneal dystrophy54
Deutscher Arzneimittel-Codex-aligned multi-dimensional quality assessment of Gastrodiae Rhizoma granules54
Comparative safety profiles of spironolactone, eplerenone, and finerenone: a pharmacovigilance study based on FAERS data from 2004 to 202454
Current situation and future development of the biopharmaceutical industry in China: A mixed-method study54
Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia54
Role and regulators of N6-methyladenosine (m6A) RNA methylation in inflammatory subtypes of asthma: a comprehensive review54
Development and therapeutic evaluation of 5D3(CC-MLN8237)3.2 antibody-theranostic conjugates for PSMA-positive prostate cancer therapy54
Selective biological activity of parthenolide derivatives — stizolin, stizolicin, and izospiciformin — isolated from the leaves of Stizolophus balsamita, in different breast cancer molecular subtypes 54
Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ25–3554
Editorial: Epigenetic modifications and cardiovascular diseases54
AduCPI2 alleviates MSU-induced acute gouty arthritis in mice by inhibiting cathepsin S and the C5a-C5aR1 axis54
Editorial: Advances in the potential treatments of gastrointestinal and liver diseases: addressing the public health burden, volume II54
In vivo pharmacokinetics of Glycyrrhiza uralensis polysaccharides54
Hepatoprotective Efficacy and Interventional Mechanism of Qijia Rougan Decoction in Liver Fibrosis54
Water extract of cacumen platycladi promotes hair growth through the Akt/GSK3β/β-catenin signaling pathway54
Activation of EP4 alleviates AKI-to-CKD transition through inducing CPT2-mediated lipophagy in renal macrophages54
EV-associated non-coding RNAs in paediatric asthma airway remodelling: current mechanistic evidence and therapeutic perspectives53
An integrative approach to uncover the components, mechanisms, and functions of traditional Chinese medicine prescriptions on male infertility53
Correction: Efficacy and safety of omadacycline for the treatment of infectious diseases: a real-world, retrospective study of 2587 patients53
Inhibition of retinal neovascularization by Dendrobium polysaccharides: a review53
Correction: Developmental and angiogenic safety profiles of novel pyridine-based chalcone53
Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses53
Methotrexate-conjugated zinc oxide nanoparticles exert a substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis52
Typing characteristics of metabolism-related genes in osteoporosis52
AI-assisted literature exploration of innovative Chinese medicine formulas52
Evaluating cardiac disorders associated with triazole antifungal agents based on the US Food and Drug Administration Adverse Event reporting system database52
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