Frontiers in Pharmacology

Article	Citations
Toxic Mechanisms of Five Heavy Metals: Mercury, Lead, Chromium, Cadmium, and Arsenic	909
Perceptions of healthcare professionals and patients on the role of the pharmacist in TB management in Pakistan: A qualitative study	365
Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food, Pharmaceutical, Biotechnological and Medicinal Applications	354
The Bone Extracellular Matrix in Bone Formation and Regeneration	342
Herb and Spices in Colorectal Cancer Prevention and Treatment: A Narrative Review	308
Advances in Oral Drug Delivery	308
Comparative effectiveness of individualized longer and standardized shorter regimens in the treatment of multidrug resistant tuberculosis in a high burden country	299
Cell-Penetrating Peptides in Diagnosis and Treatment of Human Diseases: From Preclinical Research to Clinical Application	276
Biodegradable Polymeric Nanoparticles for Drug Delivery to Solid Tumors	262
Molecular Sets (MOSES): A Benchmarking Platform for Molecular Generation Models	261
Dietary Polyphenols and Their Role in Oxidative Stress-Induced Human Diseases: Insights Into Protective Effects, Antioxidant Potentials and Mechanism(s) of Action	239
Nanocurcumin: A Promising Candidate for Therapeutic Applications	215
PI3K/AKT Signal Pathway: A Target of Natural Products in the Prevention and Treatment of Alzheimer’s Disease and Parkinson’s Disease	178
DNA Repair Pathways in Cancer Therapy and Resistance	175
COVID-19: Is There Evidence for the Use of Herbal Medicines as Adjuvant Symptomatic Therapy?	171
Activation of PI3K/AKT/mTOR Pathway Causes Drug Resistance in Breast Cancer	165
Discovering Anti-Cancer Drugs via Computational Methods	155
The Therapeutic Potential of Anthocyanins: Current Approaches Based on Their Molecular Mechanism of Action	154
The Role of the CXCL12/CXCR4/CXCR7 Chemokine Axis in Cancer	151
Uric Acid and Cardiovascular Disease: An Update From Molecular Mechanism to Clinical Perspective	150
From Animal Poisons and Venoms to Medicines: Achievements, Challenges and Perspectives in Drug Discovery	149
Comprehensive Analysis of Cuproptosis-Related Genes in Immune Infiltration and Prognosis in Melanoma	144
A Snapshot of the Global Race for Vaccines Targeting SARS-CoV-2 and the COVID-19 Pandemic	143
Overview of OxLDL and Its Impact on Cardiovascular Health: Focus on Atherosclerosis	143
SIRT1 Activation by Natural Phytochemicals: An Overview	142

PROTAC: An Effective Targeted Protein Degradation Strategy for Cancer Therapy	141
Pharmacological Properties of Chalcones: A Review of Preclinical Including Molecular Mechanisms and Clinical Evidence	140
PD-1/PD-L1 Checkpoint Inhibitors in Tumor Immunotherapy	138
Dopamine Receptor Subtypes, Physiology and Pharmacology: New Ligands and Concepts in Schizophrenia	137
Phytosterols: From Preclinical Evidence to Potential Clinical Applications	137
Fluvoxamine: A Review of Its Mechanism of Action and Its Role in COVID-19	131
Response to the Novel Corona Virus (COVID-19) Pandemic Across Africa: Successes, Challenges, and Implications for the Future	128
Medicinal Plants as Sources of Active Molecules Against COVID-19	125
Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review	124
Non-Alcoholic Steatohepatitis: A Review of Its Mechanism, Models and Medical Treatments	118
AKT Inhibitors: New Weapons in the Fight Against Breast Cancer?	118
The Pharmacological Action of Kaempferol in Central Nervous System Diseases: A Review	115
Knowledge Mapping of Drug-Induced Liver Injury: A Scientometric Investigation (2010–2019)	114
A Systematic Review of Plants With Antibacterial Activities: A Taxonomic and Phylogenetic Perspective	114
Neurodegenerative Disease and the NLRP3 Inflammasome	113
Clinically-Relevant ABC Transporter for Anti-Cancer Drug Resistance	112
Indian Medicinal Plants and Formulations and Their Potential Against COVID-19–Preclinical and Clinical Research	110
The Evasion Mechanisms of Cancer Immunity and Drug Intervention in the Tumor Microenvironment	109
Oral Curcumin With Piperine as Adjuvant Therapy for the Treatment of COVID-19: A Randomized Clinical Trial	109
Resveratrol Modulates the Gut Microbiota and Inflammation to Protect Against Diabetic Nephropathy in Mice	106
Mesenchymal Stem Cell–Derived Exosomes: A Promising Biological Tool in Nanomedicine	104
P2X7 in Cancer: From Molecular Mechanisms to Therapeutics	104
Cellular and Molecular Pathways of COVID-19 and Potential Points of Therapeutic Intervention	104
Cellular Mechanisms of Liver Fibrosis	101
Anti-SARS-CoV Natural Products With the Potential to Inhibit SARS-CoV-2 (COVID-19)	100
Novel and Emerging Therapies for Inflammatory Bowel Disease	100
Heavy Metal Contaminations in Herbal Medicines: Determination, Comprehensive Risk Assessments, and Solutions	99
Recent Advances in NAMPT Inhibitors: A Novel Immunotherapic Strategy	99
Pharmacogenetics Guidelines: Overview and Comparison of the DPWG, CPIC, CPNDS, and RNPGx Guidelines	98
Combination of Ruxolitinib and Eculizumab for Treatment of Severe SARS-CoV-2-Related Acute Respiratory Distress Syndrome: A Controlled Study	97
Challenges for Drug Repurposing in the COVID-19 Pandemic Era	97
Current Prevention of COVID-19: Natural Products and Herbal Medicine	97
A Comprehensive Review on the Therapeutic Potential of Curcuma longa Linn. in Relation to its Major Active Constituent Curcumin	97
Neutrophilia and NETopathy as Key Pathologic Drivers of Progressive Lung Impairment in Patients With COVID-19	96
A Review on the Potential Use of Medicinal Plants From Asteraceae and Lamiaceae Plant Family in Cardiovascular Diseases	96
G Protein-Coupled Receptors in Taste Physiology and Pharmacology	95
Drug Shortage: Causes, Impact, and Mitigation Strategies	95
Interplay of EMT and CSC in Cancer and the Potential Therapeutic Strategies	95
Remimazolam: Non-Clinical and Clinical Profile of a New Sedative/Anesthetic Agent	94
Cinnamomum Species: Bridging Phytochemistry Knowledge, Pharmacological Properties and Toxicological Safety for Health Benefits	93
Baicalin Prevents Myocardial Ischemia/Reperfusion Injury Through Inhibiting ACSL4 Mediated Ferroptosis	93
The Role of Oxidative Stress and Natural Antioxidants in Ovarian Aging	93
The Drug Repurposing for COVID-19 Clinical Trials Provide Very Effective Therapeutic Combinations: Lessons Learned From Major Clinical Studies	93
Advanced Approaches to Breast Cancer Classification and Diagnosis	89
Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease	89
Passiflora edulis: An Insight Into Current Researches on Phytochemistry and Pharmacology	88
Repurposing Drugs, Ongoing Vaccine, and New Therapeutic Development Initiatives Against COVID-19	86
Immune Checkpoint Inhibitor-Related Cytokine Release Syndrome: Analysis of WHO Global Pharmacovigilance Database	86
Celastrol: A Review of Useful Strategies Overcoming its Limitation in Anticancer Application	86
Natural Compounds With Antimicrobial and Antiviral Effect and Nanocarriers Used for Their Transportation	86

Immunosuppressive Drugs and COVID-19: A Review	86
Exploring Phytochemicals for Combating Antibiotic Resistance in Microbial Pathogens	85
Targeting the Integrated Stress Response in Cancer Therapy	84
Efficacy, Chemical Constituents, and Pharmacological Actions of Radix Paeoniae Rubra and Radix Paeoniae Alba	84
SIRT1 and SIRT2 Activity Control in Neurodegenerative Diseases	83
Kuijieyuan Decoction Improved Intestinal Barrier Injury of Ulcerative Colitis by Affecting TLR4-Dependent PI3K/AKT/NF-κB Oxidative and Inflammatory Signaling and Gut Microbiota	82
FDX1 can Impact the Prognosis and Mediate the Metabolism of Lung Adenocarcinoma	81
Polyphenols as Antitumor Agents Targeting Key Players in Cancer-Driving Signaling Pathways	81
Matrine: A Promising Natural Product With Various Pharmacological Activities	80
Psychedelic Communitas: Intersubjective Experience During Psychedelic Group Sessions Predicts Enduring Changes in Psychological Wellbeing and Social Connectedness	80
The Role of Tumor Inflammatory Microenvironment in Lung Cancer	79
Peroxisome Proliferator-Activated Receptors: Experimental Targeting for the Treatment of Inflammatory Bowel Diseases	79
Formation, Signaling and Occurrence of Specialized Pro-Resolving Lipid Mediators—What is the Evidence so far?	79
Targeting Neutrophils to Treat Acute Respiratory Distress Syndrome in Coronavirus Disease	78
Curcumin as a Potential Treatment for COVID-19	78
Neuropharmacological Effects of Quercetin: A Literature-Based Review	77
Clinical Insights Into Novel Immune Checkpoint Inhibitors	76
DPP4 and ACE2 in Diabetes and COVID-19: Therapeutic Targets for Cardiovascular Complications?	76
Functions and Diseases of the Retinal Pigment Epithelium	75
Genistein: A Review on its Anti-Inflammatory Properties	75
Eicosanoids in Cancer: New Roles in Immunoregulation	75
Clinical Review: Navitoclax as a Pro-Apoptotic and Anti-Fibrotic Agent	75
Hyaluronic Acid-Mediated Drug Delivery System Targeting for Inflammatory Skin Diseases: A Mini Review	75
Progress in the Understanding of the Mechanism of Tamoxifen Resistance in Breast Cancer	74
Epilepsy-Related Voltage-Gated Sodium Channelopathies: A Review	74
Pharmacological Effects of Salvianolic Acid B Against Oxidative Damage	74
Idiopathic Pulmonary Fibrosis: An Update on Pathogenesis	74
The Mechanism of Ferroptosis and Applications in Tumor Treatment	73
Herbal Medicine in the Treatment of Non-Alcoholic Fatty Liver Diseases-Efficacy, Action Mechanism, and Clinical Application	73
Chinese Patent Medicines in the Treatment of Coronavirus Disease 2019 (COVID-19) in China	73
Baicalin Inhibits Ferroptosis in Intracerebral Hemorrhage	73
Mechanisms of Chemotherapy-Induced Neurotoxicity	72
Pharmacotherapy of Behavioral and Psychological Symptoms of Dementia: State of the Art and Future Progress	70
The Biological Functions and Clinical Applications of Integrins in Cancers	70
Oxidative Stress and Hyper-Inflammation as Major Drivers of Severe COVID-19 and Long COVID: Implications for the Benefit of High-Dose Intravenous Vitamin C	69
The Inhibitory Effect of 6-Gingerol on Ubiquitin-Specific Peptidase 14 Enhances Autophagy-Dependent Ferroptosis and Anti-Tumor in vivo and in vitro	69
The Potential Role of Heparin in Patients With COVID-19: Beyond the Anticoagulant Effect. A Review	69
Analysis of Models of Doxorubicin-Induced Cardiomyopathy in Rats and Mice. A Modern View From the Perspective of the Pathophysiologist and the Clinician	68
Trends in Antidiabetic Drug Discovery: FDA Approved Drugs, New Drugs in Clinical Trials and Global Sales	68
Pyroptosis in the Initiation and Progression of Atherosclerosis	68
Fisetin Attenuates Doxorubicin-Induced Cardiomyopathy In Vivo and In Vitro by Inhibiting Ferroptosis Through SIRT1/Nrf2 Signaling Pathway Activation	68
Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient	67
Best Practice in the chemical characterisation of extracts used in pharmacological and toxicological research—The ConPhyMP—Guidelines12	67
Potential Therapeutic Options for COVID-19: Current Status, Challenges, and Future Perspectives	67
Fecal Microbiota Transplantation for the Treatment of Inflammatory Bowel Disease: An Update	67
Caspase-9: A Multimodal Therapeutic Target With Diverse Cellular Expression in Human Disease	66
Safety and Efficacy of Bromodomain and Extra-Terminal Inhibitors for the Treatment of Hematological Malignancies and Solid Tumors: A Systematic Study of Clinical Trials	66
Repurposing Sigma-1 Receptor Ligands for COVID-19 Therapy?	65
Chlorogenic Acid Improves NAFLD by Regulating gut Microbiota and GLP-1	65
Eicosanoids in Cancer: Prostaglandin E2 Receptor 4 in Cancer Therapeutics and Immunotherapy	65
Analgesic Effect of Acetaminophen: A Review of Known and Novel Mechanisms of Action	65
Intranasal Delivery of Targeted Nanoparticles Loaded With miR-132 to Brain for the Treatment of Neurodegenerative Diseases	65
Calming the Storm: Natural Immunosuppressants as Adjuvants to Target the Cytokine Storm in COVID-19	65
Research progress of glutathione peroxidase family (GPX) in redoxidation	65
Therapeutic Alliance and Rapport Modulate Responses to Psilocybin Assisted Therapy for Depression	64
A Review of the Pharmacological Properties of Psoralen	64
The Therapeutic Landscape of Rheumatoid Arthritis: Current State and Future Directions	64
An Update on Antiviral Therapy Against SARS-CoV-2: How Far Have We Come?	64
Recommendation of Antimicrobial Dosing Optimization During Continuous Renal Replacement Therapy	64
Understanding the role of the gut microbiome in gastrointestinal cancer: A review	63
Integrated PPI- and WGCNA-Retrieval of Hub Gene Signatures Shared Between Barrett's Esophagus and Esophageal Adenocarcinoma	63
Insight Into the Prospects for RNAi Therapy of Cancer	63
Software Tools for Model-Informed Precision Dosing: How Well Do They Satisfy the Needs?	63
Post-treatment With Irisin Attenuates Acute Kidney Injury in Sepsis Mice Through Anti-Ferroptosis via the SIRT1/Nrf2 Pathway	62
JAK/STAT Signaling: Molecular Targets, Therapeutic Opportunities, and Limitations of Targeted Inhibitions in Solid Malignancies	62
Chemotherapeutics-Induced Intestinal Mucositis: Pathophysiology and Potential Treatment Strategies	61
PD-1/PD-L1 Based Combinational Cancer Therapy: Icing on the Cake	61
Cordyceps spp.: A Review on Its Immune-Stimulatory and Other Biological Potentials	61
Phytochemicals as a Complement to Cancer Chemotherapy: Pharmacological Modulation of the Autophagy-Apoptosis Pathway	61
Dysfunctional Vascular Endothelium as a Driver of Atherosclerosis: Emerging Insights Into Pathogenesis and Treatment	61
Traditional Herbal Medicines, Bioactive Metabolites, and Plant Products Against COVID-19: Update on Clinical Trials and Mechanism of Actions	61
Postoperative Ileus and Postoperative Gastrointestinal Tract Dysfunction: Pathogenic Mechanisms and Novel Treatment Strategies Beyond Colorectal Enhanced Recovery After Surgery Protocols	61
COVID-19 Therapeutic Options Under Investigation	61
Cannabidiol as a Therapeutic Target: Evidence of its Neuroprotective and Neuromodulatory Function in Parkinson’s Disease	61
Transforming Growth Factor-Beta (TGF-β) Signaling in Cancer-A Betrayal Within	61
α1-Adrenergic Receptors in Neurotransmission, Synaptic Plasticity, and Cognition	60
Sinapic Acid Ameliorates the Progression of Streptozotocin (STZ)-Induced Diabetic Nephropathy in Rats via NRF2/HO-1 Mediated Pathways	60
Calcium Permeable Channels in Cancer Hallmarks	60
Possible Benefits of Faecalibacterium prausnitzii for Obesity-Associated Gut Disorders	60
Tanshinone IIA: A Review of its Anticancer Effects	60

Metformin: A Novel Weapon Against Inflammation	60
Multi-Target Approaches in Metabolic Syndrome	60
System Xc−/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy	60
Lactoferrin Against SARS-CoV-2: In Vitro and In Silico Evidences	60
Improvement of Gold Nanorods in Photothermal Therapy: Recent Progress and Perspective	59
Mitochondria Targeted Viral Replication and Survival Strategies—Prospective on SARS-CoV-2	58
NSAID–Gut Microbiota Interactions	58
Efficacy and Safety of Sophora flavescens (Kushen) Based Traditional Chinese Medicine in the Treatment of Ulcerative Colitis: Clinical Evidence and Potential Mechanisms	58
The Role of Interleukin-8 in Lung Inflammation and Injury: Implications for the Management of COVID-19 and Hyperinflammatory Acute Respiratory Distress Syndrome	58
Accelerating Therapeutics for Opportunities in Medicine: A Paradigm Shift in Drug Discovery	58
Untargeted Metabolomic Analysis of the Effects and Mechanism of Nuciferine Treatment on Rats With Nonalcoholic Fatty Liver Disease	58
Myricetin Inhibits SARS-CoV-2 Viral Replication by Targeting Mpro and Ameliorates Pulmonary Inflammation	57
Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2	57
Application of Pharmacokinetic-Pharmacodynamic Modeling in Drug Delivery: Development and Challenges	57
Necroptosis: A Novel Pathway in Neuroinflammation	57
Formononetin Attenuates Airway Inflammation and Oxidative Stress in Murine Allergic Asthma	56
A Comprehensive Account on Recent Progress in Pharmacological Activities of Benzimidazole Derivatives	56
MicroRNA as an Important Target for Anticancer Drug Development	56
Glucosinolates From Cruciferous Vegetables and Their Potential Role in Chronic Disease: Investigating the Preclinical and Clinical Evidence	56
Preliminary Experience With Low Molecular Weight Heparin Strategy in COVID-19 Patients	56
The Potential of Antiviral Peptides as COVID-19 Therapeutics	56
Methylene Blue Inhibits the SARS-CoV-2 Spike–ACE2 Protein-Protein Interaction–a Mechanism that can Contribute to its Antiviral Activity Against COVID-19	56
Phytochemistry and Pharmacological Activities of Wolfiporia cocos (F.A. Wolf) Ryvarden & Gilb	56
Integrated Metagenomic and Metabolomic Analyses of the Effect of Astragalus Polysaccharides on Alleviating High-Fat Diet–Induced Metabolic Disorders	55
Interleukin-6: A Novel Target for Cardio-Cerebrovascular Diseases	55
Formulation and Development of Transferrin Targeted Solid Lipid Nanoparticles for Breast Cancer Therapy	55
Medicinal Plants in COVID-19: Potential and Limitations	55
Advancements in Hydrogel-Based Drug Sustained Release Systems for Bone Tissue Engineering	55
Turning the Tide: Natural Products and Natural-Product-Inspired Chemicals as Potential Counters to SARS-CoV-2 Infection	55
GLP-1 Receptor Agonists in Diabetic Kidney Disease: From Clinical Outcomes to Mechanisms	55
1,2,3-Triazole-Containing Compounds as Anti–Lung Cancer Agents: Current Developments, Mechanisms of Action, and Structure–Activity Relationship	54
Bibliometric Analysis of Global Research on Cancer Photodynamic Therapy: Focus on Nano-Related Research	54
The Role of Photoactivated and Non-Photoactivated Verteporfin on Tumor	54
Gastrin Attenuates Renal Ischemia/Reperfusion Injury by a PI3K/Akt/Bad-Mediated Anti-apoptosis Signaling	54
A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine	54
Gastroprotective Effect of Sinapic Acid on Ethanol-Induced Gastric Ulcers in Rats: Involvement of Nrf2/HO-1 and NF-κB Signaling and Antiapoptotic Role	54
Withania somnifera (L.) Dunal: Opportunity for Clinical Repurposing in COVID-19 Management	53
New Insights Into Gut-Bacteria-Derived Indole and Its Derivatives in Intestinal and Liver Diseases	53
Potential Natural Products Against Respiratory Viruses: A Perspective to Develop Anti-COVID-19 Medicines	53
A Systematic Review of the Preventive and Therapeutic Effects of Naringin Against Human Malignancies	53
Bibliometric Analysis of the Inflammasome and Pyroptosis in Brain	53
Heterocyclic Compounds: Pharmacology of Pyrazole Analogs From Rational Structural Considerations	53
Monoamine Oxidase Inhibitors: A Review of Their Anti-Inflammatory Therapeutic Potential and Mechanisms of Action	53
Minor Cannabinoids: Biosynthesis, Molecular Pharmacology and Potential Therapeutic Uses	53
Traditional Chinese Medicine in Depression Treatment: From Molecules to Systems	52
Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer’s Disease Brain Tissue Reveals Disease-Associated Signatures	52
SARS-CoV-2 Switches ‘on’ MAPK and NFκB Signaling via the Reduction of Nuclear DUSP1 and DUSP5 Expression	52
Natural Compounds as Medical Strategies in the Prevention and Treatment of Psychiatric Disorders Seen in Neurological Diseases	51
The Advancing of Selenium Nanoparticles Against Infectious Diseases	51
Glomerular Endothelial Cells as Instigators of Glomerular Sclerotic Diseases	51
Enteric Coronavirus Infection and Treatment Modeled With an Immunocompetent Human Intestine-On-A-Chip	51
Phytochemistry, Pharmacology and Medicinal Uses of Plants of the Genus Salix: An Updated Review	51
New Trends in Pharmacological Treatments for Osteoarthritis	51
Effectiveness and Safety of Oral Anticoagulants in Older Patients With Atrial Fibrillation: A Systematic Review and Meta-Analysis	50
Dynamic Interleukin-6 Level Changes as a Prognostic Indicator in Patients With COVID-19	50
Favipiravir Versus Arbidol for Clinical Recovery Rate in Moderate and Severe Adult COVID-19 Patients: A Prospective, Multicenter, Open-Label, Randomized Controlled Clinical Trial	50
Salidroside Attenuates Cognitive Dysfunction in Senescence-Accelerated Mouse Prone 8 (SAMP8) Mice and Modulates Inflammation of the Gut-Brain Axis	50
First-Line Immune-Checkpoint Inhibitors in Non-Small Cell Lung Cancer: Current Landscape and Future Progress	50
Sodium–Glucose CoTransporter-2 Inhibitor Empagliflozin Ameliorates Sunitinib-Induced Cardiac Dysfunction via Regulation of AMPK–mTOR Signaling Pathway–Mediated Autophagy	50
Crosstalk Between Dysfunctional Mitochondria and Inflammation in Glaucomatous Neurodegeneration	50
Therapeutic Effects of Naringin in Rheumatoid Arthritis: Network Pharmacology and Experimental Validation	50
Pharmacological Activities and Mechanisms of Hirudin and Its Derivatives - A Review	49
Calcific Aortic Valve Disease-Natural History and Future Therapeutic Strategies	49
Natural Anti-Inflammatory Compounds as Drug Candidates for Inflammatory Bowel Disease	49
Innate Immunity in Diabetic Wound Healing: Focus on the Mastermind Hidden in Chronic Inflammatory	49
Role of Neuroinflammation in Autism Spectrum Disorder and the Emergence of Brain Histaminergic System. Lessons Also for BPSD?	49
Does Oral Apigenin Have Real Potential for a Therapeutic Effect in the Context of Human Gastrointestinal and Other Cancers?	49
Pharmacological Activities of Psoralidin: A Comprehensive Review of the Molecular Mechanisms of Action	49
Inflammatory Bowel Disease and Risk of Colorectal Cancer: An Overview From Pathophysiology to Pharmacological Prevention	49
Bilirubin Nanoparticles Reduce Diet-Induced Hepatic Steatosis, Improve Fat Utilization, and Increase Plasma β-Hydroxybutyrate	49
Phytochemicals: Potential Lead Molecules for MDR Reversal	49
Targeting the Wnt/β-Catenin Signaling Pathway as a Potential Therapeutic Strategy in Renal Tubulointerstitial Fibrosis	49
Nano and Microparticles as Potential Oral Vaccine Carriers and Adjuvants Against Infectious Diseases	48
Kaempferol Protects Blood Vessels From Damage Induced by Oxidative Stress and Inflammation in Association With the Nrf2/HO-1 Signaling Pathway	48
COVID-19: Famotidine, Histamine, Mast Cells, and Mechanisms	48
Inulin Exerts Beneficial Effects on Non-Alcoholic Fatty Liver Disease via Modulating gut Microbiome and Suppressing the Lipopolysaccharide-Toll-Like Receptor 4-Mψ-Nuclear Factor-κB-Nod-Like Receptor P	48
Analysis of Antidepressant Activity of Huang-Lian Jie-Du Decoction Through Network Pharmacology and Metabolomics	48
A Comprehensive Review of Clinical Cardiotoxicity Incidence of FDA-Approved Small-Molecule Kinase Inhibitors	48
Diabetic Nephropathy: Novel Molecular Mechanisms and Therapeutic Targets	48
Diallyl Disulfide: A Bioactive Garlic Compound with Anticancer Potential	48
A Review on Plant Bioactive Compounds and Their Modes of Action Against Coronavirus Infection	48
Gut microbiome and human health: Exploring how the probiotic genus Lactobacillus modulate immune responses	48
Mitochondrial Iron Overload-Mediated Inhibition of Nrf2-HO-1/GPX4 Assisted ALI-Induced Nephrotoxicity	48
Bibliometric Analysis of Global Research Trends on Ultrasound Microbubble: A Quickly Developing Field	47
Alleviation of Depression by Glucagon-Like Peptide 1 Through the Regulation of Neuroinflammation, Neurotransmitters, Neurogenesis, and Synaptic Function	47
Medicinal Prospects of Antioxidants From Algal Sources in Cancer Therapy	47
Lidocaine Promoted Ferroptosis by Targeting miR-382-5p /SLC7A11 Axis in Ovarian and Breast Cancer	47
A Review of Treatment of Coronavirus Disease 2019 (COVID-19): Therapeutic Repurposing and Unmet Clinical Needs	47
Total Flavones of Abelmoschus manihot Ameliorates Podocyte Pyroptosis and Injury in High Glucose Conditions by Targeting METTL3-Dependent m6A Modification-Mediated NLRP3-Inflammasome Activation and PT	47
The Role of NLRP3 Inflammasome in Alzheimer’s Disease and Potential Therapeutic Targets	47
Deferoxamine Alleviates Osteoarthritis by Inhibiting Chondrocyte Ferroptosis and Activating the Nrf2 Pathway	46
Current State and Future Directions of Intranasal Delivery Route for Central Nervous System Disorders: A Scientometric and Visualization Analysis	46
Pharmacogenetics in Psychiatry: An Update on Clinical Usability	46
Simiao Decoction Alleviates Gouty Arthritis by Modulating Proinflammatory Cytokines and the Gut Ecosystem	46
Inflammatory Caspases Drive Pyroptosis in Acute Lung Injury	46