Frontiers in Pharmacology

Article	Citations
Pre- and post-chemotherapy spermatogenesis in male patients with malignant bone and soft tissue tumors	557
Individualized, dynamic, and full-course vancomycin dosing prediction: a study on the customized dose model	365
Metabolite-assisted models improve risk prediction of coronary heart disease in patients with diabetes	325
Potential of resveratrol in the treatment of interstitial lung disease	307
Editorial: Women in nanomedicine	266
Title: Understanding a Low Vitamin D State in the Context of COVID-19	264
The forensic aspects of suicide and neurotrophin factors: a research study	236
Understanding Stakeholder Views Regarding the Design of an Intervention Trial to Reduce Anticholinergic Burden: A Qualitative Study	217
Strategies for salvage therapy post CAR-T therapy failure in refractory/relapsed multiple myeloma patients	179
RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway	177
Overview of Cannabis including Kampo Medicine and Therapy for Treatment of Dementia: A Review	162
In vitro effect of hydroxychloroquine on pluripotent stem cells and their cardiomyocytes derivatives	161
Harnessing the power of natural alkaloids: the emergent role in epilepsy therapy	158
Several major herb pairs containing Coptidis rhizoma: a review of key traditional uses, constituents and compatibility effects	157
Cost-effectiveness analysis of lenvatinib plus pembrolizumab compared with chemotherapy for patients with previously treated mismatch repair proficient advanced endometrial cancer in China	152
Plant Source Derived Compound Exhibited In Silico Inhibition of Membrane Glycoprotein In SARS-CoV-2: Paving the Way to Discover a New Class of Compound For Treatment of COVID-19	149
Improvement of solubility, dissolution, and bioavailability of phenytoin intercalated in Mg-Al layered double hydroxide	148
Case report: Dezocine’s rapid and sustained antidepressant effects	146
Reynoutria japonica Houtt for Acute Respiratory Tract Infections in Adults and Children: A Systematic Review	143
Transcriptome analysis revealed the role of mTOR and MAPK signaling pathways in the white strain of Hypsizygus marmoreus extracts-induced cell death of human hepatoma Hep3B cells	141
Exploration of the Mechanism of Salvianolic Acid for Injection Against Ischemic Stroke: A Research Based on Computational Prediction and Experimental Validation	140
T-type calcium channel modulation by hydrogen sulfide in neuropathic pain conditions	139
Comprehensive Analysis of Chemical Structures That Have Been Tested as CFTR Activating Substances in a Publicly Available Database CandActCFTR	138
Potential Treat-to-Target Approach for Methamphetamine Use Disorder: A Pilot Study of Adenosine 2A Receptor Antagonist With Positron Emission Tomography	136
Editorial: Autoimmune and Inflammatory Rheumatic Diseases: Identifying Biomarkers of Response to Therapy With Biologics	133

Comparative study of the effects of the three kinds of Kampo-hozai: Ninjinyoeito, Hochuekkito, and Juzentaihoto on anxious and low sociability behavior using NPY-knockout zebrafish	129
Cost-utility analysis of using paliperidone palmitate in schizophrenia in China	126
Identification of potential quality markers of Zishen Yutai pill based on spectrum–effect relationship analysis	124
Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation	123
Editorial: Leukocyte biology and muscle pathology: Leukocytes as potential targets to control muscle inflammation, mass, and pain	117
Consideration in Randomized Placebo-Controlled Trial on Neck Pain to Avoid the Placebo Effect in Analgesic Action	117
The therapeutic potential of natural metabolites in targeting endocrine-independent HER-2-negative breast cancer	114
Editorial: Therapeutic drug monitoring (TDM): a useful tool for pediatric pharmacology applied to routine clinical practice, Volume II	113
Development of Synergy-Based Combination for Learning and Memory Using in vitro, in vivo and TLC-MS-Bioautographic Studies	112
Editorial: Oral mucosa and disorders: from drug discovery to development and translation	112
Network pharmacology and experimental verification-based strategy to explore the underlying mechanism of Liu Jun An Wei formula in the treatment of gastrointestinal reactions caused by chemotherapy fo	108
Effects of public reporting of prescription indicators on patient choices: evidence from propensity scores matching	106
Impact of domiciliary administration of NSAIDs on COVID-19 hospital outcomes: an unCoVer analysis	106
Sex, Pramipexole and Tiagabine Affect Behavioral and Hormonal Response to Traumatic Stress in a Mouse Model of PTSD	103
Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers	102
Apple pectin-based Zataria multiflora essential oil (ZEO) nanoemulsion: An approach to enhance ZEO DNA damage induction in breast cancer cells as in vitro and in silico studies reveal	101
Editorial: Interplays and Functions of Gaseous Mediators: From Underlying Mechanisms to Therapeutic Approaches in Cardiovascular Diseases	101
Title: P2x7 Receptor Activation and Estrogen Status Drive Neuroinflammatory Mechanisms in a Rat Model for Dry Eye	101
Editorial: Streaming inflammation: From damage to healing and resilience–Volume II	100
Sputum microbe community alterations induced by long-term inhaled corticosteroid use are associated with airway function in chronic obstructive pulmonary disease patients based on metagenomic next-gen	100
Antisense Oligonucleotide-Based Therapy on miR-181a-5p Alleviates Cartilage Degradation of Temporomandibular Joint Osteoarthritis via Promoting SIRT1	100
Liu Shen Capsule Alters Airway Microbiota Composition and Metabolite Profiles in Healthy Humans	100
A Multicenter Study of 239 Patients Aged Over 70 Years With Diffuse Large B-Cell Lymphoma in China	98
In vivo pharmacokinetics of Glycyrrhiza uralensis polysaccharides	95
Cytotoxicity and reversal effect of sertraline, fluoxetine, and citalopram on MRP1- and MRP7-mediated MDR	95
Editorial: Evolution of phytochemicals and phytotherapies in the treatment and management of cancer: targeted strategies in cancer precision medicine	94
Does preterm birth increase the initiation of antidepressant use during the postpartum? A population-based investigation	94
Hepatoprotective Efficacy and Interventional Mechanism of Qijia Rougan Decoction in Liver Fibrosis	94
Extracellular vesicles mediate biological information delivery: A double-edged sword in cardiac remodeling after myocardial infarction	93
Experience of a Strategy Including CYP2C19 Preemptive Genotyping Followed by Therapeutic Drug Monitoring of Voriconazole in Patients Undergoing Allogenic Hematopoietic Stem Cell Transplantation	93
Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study	90
Editorial: Advances on targeted nanomedicines for atherosclerosis	90
Editorial: Impact of anesthetics on cancer behavior and outcome	90
Editorial: Dissecting Traditional Medicine via Chemical and Biochemical Techniques: Advanced Analytics and Novel Paradigms	89
Canagliflozin Prevents Lipid Accumulation, Mitochondrial Dysfunction, and Gut Microbiota Dysbiosis in Mice With Diabetic Cardiovascular Disease	88
Editorial: Pharmacogenetics and pharmacogenomics in Latin America: ethnic variability, new insights in advances and perspectives: a RELIVAF-CYTED initiative, Volume II	87
Dioscin Reduces Vascular Damage in the Retina of db/db Mice by Inhibiting the VEGFA Signaling Pathway	87
Clinical study of ganshuang granule combined with tenofovir in the treatment of chronic hepatitis B complicated with nonalcoholic fatty liver disease	86
Cost-effectiveness of empagliflozin for the treatment of heart failure: a systematic review	86
Escitalopram oxalate-loaded chitosan nanoparticle in situ gel formulation intended for direct nose-to-brain delivery: in vitro, ex vivo, and in vivo pharmacokinetic evaluation	85
Olmesartan Attenuates Single-Lung Ventilation Induced Lung Injury via Regulating Pulmonary Microbiota	84
The Function of Natural Polysaccharides in the Treatment of Ulcerative Colitis	83
Qishen Granule (QSG) Inhibits Monocytes Released From the Spleen and Protect Myocardial Function via the TLR4-MyD88-NF-κB p65 Pathway in Heart Failure Mice	83
Identification of highly effective inhibitors against SARS-CoV-2 main protease: From virtual screening to in vitro study	83
Pterostilbene Alleviates Cholestasis by Promoting SIRT1 Activity in Hepatocytes and Macrophages	83
Editorial: Methods in predictive toxicology 2023	82
Post-marketing safety surveillance of dalfampridine for multiple sclerosis using FDA adverse event reporting system	81
Corrigendum: Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling	80
New use of an old drug: mechanism of oseltamivir phosphate inhibiting liver cancer through regulation of lipophagy via NEU1	80
Corrigendum: Xenon attenuated neonatal lipopolysaccharide exposure induced neuronal necroptosis and subsequently improved cognition in juvenile rats	79

Editorial: Utilizing omics strategies to discover new drug targets for cancers	79
Corrigendum: Sanguisorba officinalis L. Suppresses Triple-Negative Breast Cancer Metastasis by Inhibiting Late-Phase Autophagy via Hif-1α/Caveolin-1 Signaling	78
Inhibitory effects of calcium channel blockers nisoldipine and nimodipine on ivacaftor metabolism and their underlying mechanism	78
Retraction: CXCL6 promotes renal interstitial fibrosis in diabetic nephropathy by activating JAK/STAT3 signaling pathway	78
Erratum: Isoflurane-lipid emulsion injection as an anticonvulsant and neuroprotectant treatment for nerve agent exposure	78
Erratum: Exploring the pharmacological action mechanism of Ligusticum Chuanxiong-Piper Longum couplet medicines on the treatment of migraine based on network pharmacology	77
Berberine Facilitates Extinction and Prevents the Return of Fear	76
Effect of Combined Perftoran and Indocyanine Green-Photodynamic Therapy on HypoxamiRs and OncomiRs in Lung Cancer Cells	76
The macrocyclic lactone oxacyclododecindione reduces fibrosis progression	76
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps	75
Pre-clinical toxicity assessment of Artemisia absinthium extract-loaded polymeric nanoparticles associated with their oral administration	75
Antirheumatoid Arthritic Effects of Sabia parviflora Wall. Leaf Extracts via the NF-κB Pathway and Transient Receptor Potential Protein Family	74
Functional effects of drugs and toxins interacting with NaV1.4	74
Discovery of novel benzylquinazoline molecules as p97/VCP inhibitors	74
Effects of long-term antipsychotic medication on brain instability in first-episode schizophrenia patients: a resting-state fMRI study	74
Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity	74
Accentuating CircRNA-miRNA-Transcription Factors Axis: A Conundrum in Cancer Research	73
Multi-omic analysis reveals that Bacillus licheniformis enhances pekin ducks growth performance via lipid metabolism regulation	73
IgG-like Bispecific Antibody CD3×EpCAM Generated by Split Intein Against Colorectal Cancer	73
Neuroregeneration of injured peripheral nerve by fraction B of catfish epidermal secretions through the reversal of the apoptotic pathway and DNA damage	73
Corrigendum: The Extract of Sonneratia apetala Leaves and Branches Ameliorates Hyperuricemia in Mice by Regulating Renal Uric Acid Transporters and Suppressing the Activation of the JAK/STAT Signaling	72
Corrigendum: The Role of High-Content Complex Dietary Fiber in Medical Nutrition Therapy for Gestational Diabetes Mellitus	71
Menisoxoisoaporphine A, a novel oxoisoaporphine alkaloid from Menispermi Rhizoma, inhibits inflammation by targeting PDE4B	71
Corrigendum: Editorial: The mechanisms of action of anti-SARS-CoV-2 drugs	71
Potential Natural Small Molecular Compounds for the Treatment of Chronic Obstructive Pulmonary Disease: An Overview	70
Role of ferroptosis in atrial fibrillation: a review	70
Corrigendum: Comparison of the effectiveness and safety of perampanel and oxcarbazepine as monotherapy in children and adolescents with newly diagnosed focal epilepsy	70
Current situation and future development of the biopharmaceutical industry in China: A mixed-method study	70
Investigating the therapeutic potential of hesperidin targeting CRISP2 in intervertebral disc degeneration and cancer risk mitigation	69
Proteomics Study Reveals the Anti-Depressive Mechanisms and the Compatibility Advantage of Chaihu-Shugan-San in a Rat Model of Chronic Unpredictable Mild Stress	69
Ferroptosis, pathogenesis and therapy in AS co-depression disease	68
Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma	68
Network pharmacology and transcriptomics reveal the mechanisms of FFBZL in the treatment of oral squamous cell carcinoma	67
Economic impact of individualized antimicrobial dose optimization in the critically ill patient in Spain	67
Development of a vaccine against the synthetic opioid U-47700	67
Gaboxadol in Fragile X Syndrome: A 12-Week Randomized, Double-Blind, Parallel-Group, Phase 2a Study	67
The clinically applied PARP inhibitor talazoparib ameliorates imiquimod-induced psoriasis in mice without reducing skin inflammation	67
Potential efficacy and mechanisms of icariin for the animal model of osteonecrosis of the femoral head	66
Editorial: Chronic pain: what is the mechanism?	66
MicroRNA 449a can Attenuate Protective Effect of Urokinase Against Pulmonary Embolism	66
Transcriptome analysis revealed the genes and major pathways involved in prunetrin treated hepatocellular carcinoma cells	65
Male mice treated with combined anti-fibrotic therapeutics, IPW5371 and tadalafil, are predisposed to adverse cardiovascular events	64
Long-term administration of bumetanide improve functional recovery after spinal cord injury in rats	64
Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models	64
Gut microbiome-mediated mechanisms in aging-related diseases: are probiotics ready for prime time?	64
An Update on the Effects of Probiotics on Gastrointestinal Cancers	63
Efficacy, safety and mechanism of Honghua Xiaoyao Pill in the treatment of peri-menopausal syndrome: A study protocol for a randomized controlled trial	63
Treatment of Poor Sperm Quality and Erectile Dysfunction With Oral Pentoxifylline: A Systematic Review	63
Case Report: Rhabdomyolysis secondary to vildagliptin overdose in a suicidal attempt: A case report and brief literature review	62
Bibliometric and visualized analysis of sodium–Glucose cotransporter 2 inhibitors	62
Hemoglobin α-derived peptides VD-hemopressin (α) and RVD-hemopressin (α) are involved in electroacupuncture inhibition of chronic pain	61
Isatin improves oligoasthenospermia caused by busulfan by regulating GSH/GPX4 axis to inhibit ferroptosis	61
Unraveling the pathogenic mechanism of a novel filamin a frameshift variant in periventricular nodular heterotopia	61
Metabolic Profiling Analysis of the Effect and Mechanism of Gushiling Capsule in Rabbits With Glucocorticoid-Induced Osteonecrosis of the Femoral Head	61
Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation	61
Centella asiatica Alters Metabolic Pathways Associated With Alzheimer’s Disease in the 5xFAD Mouse Model of ß-Amyloid Accumulation	61
Editorial: Genomic discoveries and pharmaceutical development in urologic tumors	60
A nano-preparation approach to enable the delivery of daphnoretin to potentiate the therapeutical efficacy in hepatocellular cancer	60
Therapeutic drug monitoring practices of anti-infectives: An Asia-wide cross-sectional survey	60
Hermansky-Pudlak Syndrome: Identification of Novel Variants in the Genes HPS3, HPS5, and DTNBP1 (HPS-7)	60
Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway	60
East Asian Herbal Medicine to Reduce Primary Pain and Adverse Events in Cancer Patients : A Systematic Review and Meta-Analysis With Association Rule Mining to Identify Core Herb Combination	60
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control	59
Drug-related problems among transfusion-dependent thalassemia patients: A real-world evidence study	59
Effects of the Full Coverage Policy of Essential Medicines on Inequality in Medication Adherence: A Longitudinal Study in Taizhou, China	59
Prospective population pharmacokinetic study of tacrolimus in adult recipients early after liver transplantation: A comparison of Michaelis-Menten and theory-based pharmacokinetic models	58
Association of EGFR Tyrosine Kinase Inhibitor Treatment With Progression-Free Survival Among Taiwanese Patients With Advanced Lung Adenocarcinoma and EGFR Mutation	58
Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether‐à‐go‐go–Related Gene and Cav1.2	58
Tailoring second-line or above therapy for patients with advanced or metastatic gastric cancer: A multicenter real-world study	57
Pterostilbene in Combination With Mitochondrial Cofactors Improve Mitochondrial Function in Cellular Models of Mitochondrial Diseases	57
Activation of EP4 alleviates AKI-to-CKD transition through inducing CPT2-mediated lipophagy in renal macrophages	57
A New Strategy for Multitarget Drug Discovery/Repositioning Through the Identification of Similar 3D Amino Acid Patterns Among Proteins Structures: The Case of Tafluprost and its Effects on Cardiac Io	57
Associations of Fentanyl, Sufentanil, and Remifentanil With Length of Stay and Mortality Among Mechanically Ventilated Patients: A Registry-Based Cohort Study	57
Development and therapeutic evaluation of 5D3(CC-MLN8237)3.2 antibody-theranostic conjugates for PSMA-positive prostate cancer therapy	56
Traditional Chinese Medicine in Treating Primary Podocytosis: From Fundamental Science to Clinical Research	56
Exploiting the anti-fibrotic effects of statins on thoracic aortic aneurysm progression: results from a meta-analysis and experimental data	56
Kinin B1R Activation Induces Endoplasmic Reticulum Stress in Primary Hypothalamic Neurons	56
Patient-Patient Similarity-Based Screening of a Clinical Data Warehouse to Support Ciliopathy Diagnosis	55
A Betulinic Acid Derivative, BA5, Induces G0/G1 Cell Arrest, Apoptosis Like-Death, and Morphological Alterations in Leishmania sp	55
The Role of Traditional Plant Knowledge in the Fight Against Infectious Diseases: A Meta-Analytic Study in the Catalan Linguistic Area	55

Wendan decoction in the treatment of nonalcoholic fatty liver disease: A systematic review and meta-analysis	55
The Protective Effects of Lipid-Lowering Agents on Cardiovascular Disease and Mortality in Maintenance Dialysis Patients: Propensity Score Analysis of a Population-Based Cohort Study	55
Efficacy of Intra-Arterial Plus Intravesical Chemotherapy for High-Risk Non-Muscle-Invasive Bladder Cancer: A Pooled Analysis	55
Quantifying the integrated physiological effects of endothelin-1 on cardiovascular and renal function in healthy subjects: a mathematical modeling analysis	55
Nephroprotective potential of Polyalthia longifolia roots against vancomycin-induced renal toxicity in experimental animals	55
Xuanfei Pingchuan Capsules Ameliorate Autophagy in Human Bronchial Epithelial Cells by Inhibiting p38 Phosphorylation	55
Effect of Fu Zheng Jie Du Formula on outcomes in patients with severe pneumonia receiving prone ventilation: a retrospective cohort study	55
Discovery of a novel natural compound, vitekwangin B, with ANO1 protein reduction properties and anticancer potential	55
Time trends and regional variations in prices of anticancer medicines in China	55
The Future of Gene Therapy for Transfusion-Dependent Beta-Thalassemia: The Power of the Lentiviral Vector for Genetically Modified Hematopoietic Stem Cells	55
Microbiome Analysis and Pharmacovigilance After Inhaled Glucocorticoid: Oral Dysbiosis With the Isolation of Three Rothia Species and Subsequent Sjögren’s Syndrome	55
Bifidobacterium Strains Present Distinct Effects on the Control of Alveolar Bone Loss in a Periodontitis Experimental Model	55
Cymensifin A: a promising pharmaceutical candidate to defeat lung cancer via cellular reactive oxygen species-mediated apoptosis	55
Water-Soluble Tomato Extract Fruitflow Alters the Phosphoproteomic Profile of Collagen-Stimulated Platelets	55
Editorial: Big data for biomedical research of inflammatory diseases	55
Factors influencing plasma concentration of voriconazole and voriconazole- N-oxide in younger adult and elderly patients	54
Side-stepping the guardian of the genome: current cancer therapeutics targeting mutant p53	54
Prediction of Immune-Related Adverse Events Induced by Immune Checkpoint Inhibitors With a Panel of Autoantibodies: Protocol of a Multicenter, Prospective, Observational Cohort Study	54
Unlocking cellular traffic jams: olive oil-mediated rescue of CNG mutant channels	54
Naoxintong capsule for treating cardiovascular and cerebrovascular diseases: from bench to bedside	54
Butyrate Treatment of DSS-Induced Ulcerative Colitis Affects the Hepatic Drug Metabolism in Mice	54
Long-Term Cardiac Damage Associated With Abdominal Irradiation in Mice	54
Three-Drug Regimens Containing Integrase Inhibitor Show Good Efficacy and Safety in Treatment-Naive Patients With HIV-1: A Bayesian Analysis	53
Neuroprotective effect of dexmedetomidine on autophagy in mice administered intracerebroventricular injections of Aβ25–35	53
Managing novel therapies and concomitant medications in chronic lymphocytic leukemia: key challenges	53
First-in-human study to assess the safety, tolerability, pharmacokinetics and immunogenicity of DS002, an anti-nerve growth factor monoclonal antibody	53
Recent clinical evidence on nutrition, novel pharmacotherapy, and vaccination in inflammatory bowel diseases	53
Immune Effect of Active Components of Traditional Chinese Medicine on Triple-Negative Breast Cancer	53
Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data	53
Model-informed precision dosing in vancomycin treatment	53
Is it possible to diagnose therapeutic adherence in mild cognitive impairment and dementia patients in clinical practice?	53
Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients	53
pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties	53
Licorice attenuates cisplatin-induced hepatotoxicity by alleviating endoplasmic reticulum stress and apoptosis	53
Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses	52
Adverse events in different administration routes of amiodarone: a pharmacovigilance study based on the FDA adverse event reporting system	52
Effects of Dexmedetomidine on Immune Cells: A Narrative Review	52
Emerging Nanotheranostics for 5-Fluorouracil in Cancer Therapy: A Systematic Review on Efficacy, Safety, and Diagnostic Capability	52
Oxylipins as therapeutic indicators of herbal medicines in cardiovascular diseases: a review	52
The efficacy of polymyxin B in treating stroke-associated pneumonia with carbapenem-resistant Gram-negative bacteria infections: a multicenter real-world study using propensity score matching	52
Lycium barbarum polysaccharide reverses drug resistance in oxaliplatin-resistant colon cancer cells by inhibiting PI3K/AKT-dependent phosphomannose isomerase	52
Magnolol Attenuates Right Ventricular Hypertrophy and Fibrosis in Hypoxia-Induced Pulmonary Arterial Hypertensive Rats Through Inhibition of the JAK2/STAT3 Signaling Pathway	51
Protective effect and mechanism of Qingfei Paidu decoction on myocardial damage mediated by influenza viruses	51
Network pharmacology, molecular docking, and experimental validation to explore the potential mechanism of Long Mu Qing Xin mixture for the treatment of attention deficit hyperactivity disorder	51
The Transcultural Adaptation and Validation of the Chinese Version of the Duke Anticoagulation Satisfaction Scale	51
The role of l-leucovorin uptake and metabolism in the modulation of 5-fluorouracil efficacy and antifolate toxicity	51
Traditional Chinese medicine in the prevention of diabetes mellitus and cardiovascular complications: mechanisms and therapeutic approaches	51
The categorizations of vasculogenic mimicry in clear cell renal cell carcinoma unveil inherent connections with clinical and immune features	51
T-Cell Exhaustion Status Under High and Low Levels of Hypoxia-Inducible Factor 1α Expression in Glioma	51
Drug-drug interactions between antithrombotics and direct-acting antivirals in hepatitis C virus (HCV) patients: A brief, updated report	51
Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice	51
Emerging Roles of Myeloid-Derived Suppressor Cells in Diabetes	51
Computational and experimental pharmacology to decode the efficacy of Theobroma cacao L. against doxorubicin-induced organ toxicity in EAC-mediated solid tumor-induced mice	51
Doxycycline for the treatment of breast cancer-related lymphedema	51
Short-Chain Naphthoquinone Protects Against Both Acute and Spontaneous Chronic Murine Colitis by Alleviating Inflammatory Responses	51
Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist: In Vitro, Preclinical, and Clinical Data	50
Advancing the use of real world evidence in health technology assessment: insights from a multi-stakeholder workshop	50
GraphTransNet: predicting epilepsy-related genes using a graph-augmented protein language model	50
Dexmedetomidine inhibits abnormal muscle hypertrophy of myofascial trigger points via TNF-α/ NF-κB signaling pathway in rats	50
Methotrexate-conjugated zinc oxide nanoparticles exert a substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis	50
Influence of the ABCB1-rs1045642 gene polymorphism on blood drug concentration in voriconazole-treated patients with severe invasive fungal infection	50
Comparative efficacy and acceptability of pharmacotherapies for postpartum depression: A systematic review and network meta-analysis	50
Research hotspots and trend analysis of cell transplantation in traumatic spinal cord injury: a bibliometric and visualized analysis	50
Inhibition of Gasdermin D-Mediated Pyroptosis Attenuates the Severity of Seizures and Astroglial Damage in Kainic Acid-Induced Epileptic Mice	50
The essential role of YAP in ERα36-mediated proliferation and the epithelial-mesenchymal transition in MCF-7 breast cancer cells	49
Ocular development after highly effective modulator treatment early in life	49
Long-term clinical course and outcomes of patients with microscopic polyangiitis-associated interstitial lung disease	49
Potential role of extracellular granzyme B in wet age-related macular degeneration and fuchs endothelial corneal dystrophy	49
Case Report: Neurofilament light chain in the follow up of progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with ocrelizumab	49
Fatal Tumour Lysis Syndrome Induced by Brigatinib in a Lung Adenocarcinoma Patient Treated With Sequential ALK Inhibitors: A Case Report	49
Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo	49
Radiosensitization effect of iridium (III) complex on lung cancer cells via mitochondria apoptosis pathway	49
Efficacy analysis of splint combined with platelet-rich plasma in the treatment of temporomandibular joint osteoarthritis	49
The Treatment With the SGLT2 Inhibitor Empagliflozin Modifies the Hepatic Metabolome of Male Zucker Diabetic Fatty Rats Towards a Protective Profile	48
Emerging Significance of Ginsenosides as Potentially Reversal Agents of Chemoresistance in Cancer Therapy	48
The functional significance of vascular DNA hypermethylation in atherosclerosis: a historical perspective	48
Bibliometric analysis of research on retinoic acid in the field of kidney disorders	48
Frankincense preparation promotes formation of inflammation-resolving lipid mediators by manipulating lipoxygenases in human innate immune cells	48
Dysregulated neuromodulation in the anterior cingulate cortex in chronic pain	47
Association between antihypertensive drugs and oral cancer: a drug target Mendelian randomization study	47
Prescription medication use of United States military service members by therapeutic classification	47
Role and regulators of N6-methyladenosine (m6A) RNA methylation in inflammatory subtypes of asthma: a comprehensive review	47
The efficacy of aminosalicylates in acute radiation enteritis: a systematic review and meta-analysis	47
Asthma Therapies on Pulmonary Tuberculosis Pneumonia in Predominant Bronchiectasis–Asthma Combination	47
Dihydroarteannuin Ameliorates Collagen-Induced Arthritis Via Inhibiting B Cell Activation by Activating the FcγRIIb/Lyn/SHP-1 Pathway	47
The brief overview, antivirus and anti-SARS-CoV-2 activity, quantitative methods, and pharmacokinetics of cepharanthine: a potential small-molecule drug against COVID-19	47
Curcumin as a potential therapeutic agent for Parkinson’s disease: a systematic review	47
Tripterygium wilfordii glycosides ameliorates collagen-induced arthritis and aberrant lipid metabolism in rats	47
LINC01559 drives osimertinib resistance in NSCLC through a ceRNA network regulating miR-320a/IGF2BP3 axis	46
ALG-bFGF Hydrogel Inhibiting Autophagy Contributes to Protection of Blood–Spinal Cord Barrier Integrity via PI3K/Akt/FOXO1/KLF4 Pathway After SCI	46
A Comprehensive Review of BET Protein Biochemistry, Physiology, and Pathological Roles	46
Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction	46
Ion Channel Dysfunction and Neuroinflammation in Migraine and Depression	46
The Impact of the Renin-Angiotensin-Aldosterone System on Inflammation, Coagulation, and Atherothrombotic Complications, and to Aggravated COVID-19	46
Pimpinellin Inhibits Collagen-induced Platelet Aggregation and Activation Through Inhibiting Granule Secretion and PI3K/Akt Pathway	46