Frontiers in Pharmacology

Papers
(The TQCC of Frontiers in Pharmacology is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Association between hyperuricemia and all-cause mortality in people taken Statins: a retrospective cohort study495
pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties402
D-cycloserine effects on COPD and depression in a murine experimental model368
GraphTransNet: predicting epilepsy-related genes using a graph-augmented protein language model338
Unraveling the pathogenic mechanism of a novel filamin a frameshift variant in periventricular nodular heterotopia336
Quantifying the integrated physiological effects of endothelin-1 on cardiovascular and renal function in healthy subjects: a mathematical modeling analysis316
Editorial: Chronic pain: what is the mechanism?297
Long-term clinical course and outcomes of patients with microscopic polyangiitis-associated interstitial lung disease272
Time trends and regional variations in prices of anticancer medicines in China260
Editorial: Impact of anesthetics on cancer behavior and outcome240
Unlocking cellular traffic jams: olive oil-mediated rescue of CNG mutant channels211
Editorial: Interplays and Functions of Gaseous Mediators: From Underlying Mechanisms to Therapeutic Approaches in Cardiovascular Diseases201
Impact of domiciliary administration of NSAIDs on COVID-19 hospital outcomes: an unCoVer analysis195
Editorial: Methods in predictive toxicology 2023187
Associations between ionomic profile and metabolic abnormalities in a murine model of sodium sulfide induced alopecia areata173
Nodosin Exerts an Anti-Colorectal Cancer Effect by Inhibiting Proliferation and Triggering Complex Cell Death in Vitro and in Vivo172
Differences in right ventricular function and response to targeted therapy between patients with IPAH and PAH-CHD169
Editorial: Utilizing omics strategies to discover new drug targets for cancers165
The functional significance of vascular DNA hypermethylation in atherosclerosis: a historical perspective158
Effect of Fu Zheng Jie Du Formula on outcomes in patients with severe pneumonia receiving prone ventilation: a retrospective cohort study158
Potential efficacy and mechanisms of icariin for the animal model of osteonecrosis of the femoral head155
Case Report: Rhabdomyolysis secondary to vildagliptin overdose in a suicidal attempt: A case report and brief literature review154
Development of a vaccine against the synthetic opioid U-47700140
Research hotspots and trend analysis of cell transplantation in traumatic spinal cord injury: a bibliometric and visualized analysis135
Association between antihypertensive drugs and oral cancer: a drug target Mendelian randomization study135
Survival analysis of a 16-year cohort of follicular lymphoma patients receiving systemic treatment in Brazil134
Editorial: Women in nanomedicine131
Identification of highly effective inhibitors against SARS-CoV-2 main protease: From virtual screening to in vitro study129
Comparison of pharmacokinetics and safety between CE-fosphenytoin sodium, fosphenytoin sodium, and phenytoin sodium after intravenous and intramuscular administration in healthy volunteers128
Traditional Chinese Medicine formula Dai-Zong-Fang alleviating hepatic steatosis in db/db mice via gut microbiota modulation118
Editorial: Evolution of phytochemicals and phytotherapies in the treatment and management of cancer: targeted strategies in cancer precision medicine116
Editorial: Leukocyte biology and muscle pathology: Leukocytes as potential targets to control muscle inflammation, mass, and pain116
Drug-drug interactions between antithrombotics and direct-acting antivirals in hepatitis C virus (HCV) patients: A brief, updated report114
Non-aromatizable androgens modulate the lipopolysaccharide induced expression of the P2X7 receptor in human adipocytes113
Consideration in Randomized Placebo-Controlled Trial on Neck Pain to Avoid the Placebo Effect in Analgesic Action111
Cost-utility analysis of using paliperidone palmitate in schizophrenia in China111
Significance of LRFN4 in prognosis and tumor microenvironment of lung adenocarcinoma108
A retrospective analysis of factors associated with the length of hospital stay in COVID-19 patients treated with Nirmatrelvir / Ritonavir107
Influence of the ABCB1-rs1045642 gene polymorphism on blood drug concentration in voriconazole-treated patients with severe invasive fungal infection107
Editorial: Advances on targeted nanomedicines for atherosclerosis107
Case Report: Neurofilament light chain in the follow up of progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with ocrelizumab106
Evaluation of variable new antigen receptors (vNARs) as a novel cathepsin S (CTSS) targeting strategy105
Transcriptome analysis revealed the genes and major pathways involved in prunetrin treated hepatocellular carcinoma cells104
Androgen receptor inhibitor ameliorates pulmonary arterial hypertension by enhancing the apoptosis level through suppressing the Notch3/Hes5 pathway102
Inhibition of retinal neovascularization by Dendrobium polysaccharides: a review102
Cymensifin A: a promising pharmaceutical candidate to defeat lung cancer via cellular reactive oxygen species-mediated apoptosis101
Case report: Dezocine’s rapid and sustained antidepressant effects101
A Multicenter Study of 239 Patients Aged Over 70 Years With Diffuse Large B-Cell Lymphoma in China99
A nano-preparation approach to enable the delivery of daphnoretin to potentiate the therapeutical efficacy in hepatocellular cancer98
Development and therapeutic evaluation of 5D3(CC-MLN8237)3.2 antibody-theranostic conjugates for PSMA-positive prostate cancer therapy98
Menisoxoisoaporphine A, a novel oxoisoaporphine alkaloid from Menispermi Rhizoma, inhibits inflammation by targeting PDE4B97
The clinically applied PARP inhibitor talazoparib ameliorates imiquimod-induced psoriasis in mice without reducing skin inflammation96
Male mice treated with combined anti-fibrotic therapeutics, IPW5371 and tadalafil, are predisposed to adverse cardiovascular events96
Research Progress of RNA Methylation Modification in Colorectal Cancer95
Which is the optimal choice in lipid-lowering therapy for reducing major cardiovascular events? a network meta-analysis95
The clinical value of screening for acetaminophen in all patients with intentional overdose or altered mental status suspected to be secondary to overdose95
Opportunities and challenges in the treatment of IgA nephropathy95
In vitro effect of hydroxychloroquine on pluripotent stem cells and their cardiomyocytes derivatives94
Network pharmacology-based and experimental identification of the effects of Renshen Yangrong decoction on myocardial infarction93
Tailoring second-line or above therapy for patients with advanced or metastatic gastric cancer: A multicenter real-world study92
Cost-effectiveness of empagliflozin for the treatment of heart failure: a systematic review91
The macrocyclic lactone oxacyclododecindione reduces fibrosis progression91
Editorial: Streaming inflammation: From damage to healing and resilience–Volume II90
Inhibition of PPARγ by BZ26, a GW9662 derivate, attenuated obesity-related breast cancer progression by inhibiting the reprogramming of mature adipocytes into to cancer associate adipocyte-like cells89
Prediction of Immune-Related Adverse Events Induced by Immune Checkpoint Inhibitors With a Panel of Autoantibodies: Protocol of a Multicenter, Prospective, Observational Cohort Study89
In situ sustained release of icariin from injectable thermosensitive PLGA-PEG-PLGA hydrogels combined with core decompression for steroid-induced osteonecrosis of femoral head88
Pharmacokinetics and absorption mechanism of tandospirone citrate87
Comparative efficacy of commercial Chinese polyherbal preparation for coronary microvascular dysfunction: a systematic review and network meta-analysis of randomized controlled trials86
Natural drugs targeting inflammation pathways can be used to treat atherosclerosis86
Endothelium glutamate receptors in brain pathology85
Ophiopogonin D increase apoptosis by activating p53 via ribosomal protein L5 and L11 and inhibiting the expression of c-Myc via CNOT285
Commentary: Iridoids derived from Valeriana jatamansi jones alleviates neuroinflammation and blood spinal cord barrier permeability after spinal cord injury by activating the Nrf2/HO-1 signaling pathw85
Cardiovascular toxicities associated with chimeric antigen receptor T-cell therapy84
Research Progress of Chinese Herbal Medicine Intervention in Renal Interstitial Fibrosis84
Dopaminergic REST is implicated in the tamoxifen-induced neuroprotection against manganese toxicity in female mice84
Cytotoxicity and reversal effect of sertraline, fluoxetine, and citalopram on MRP1- and MRP7-mediated MDR84
Phyllanthus emblica aqueous extract retards hepatic steatosis and fibrosis in NAFLD mice in association with the reshaping of intestinal microecology84
Cost-effectiveness analysis of lenvatinib plus pembrolizumab compared with chemotherapy for patients with previously treated mismatch repair proficient advanced endometrial cancer in China83
Screening of anti-heart failure active compounds from fangjihuangqi decoction in verapamil-induced zebrafish model by anti-heart failure index approach83
Investigation of anti-nociceptive, anti-inflammatory potential and ADMET studies of pure compounds isolated from Isodon rugosus Wall. ex Benth83
The essential role of YAP in ERα36-mediated proliferation and the epithelial-mesenchymal transition in MCF-7 breast cancer cells82
Editorial: Genomic discoveries and pharmaceutical development in urologic tumors82
HtrA2/Omi: potential therapeutic targets for neurodegenerative diseases82
Bibliometric analysis of research on retinoic acid in the field of kidney disorders81
Integrated chemometric evaluation of morphological traits, chemical composition, and hepatotoxicity of Polygonum multiflorum81
Dexmedetomidine inhibits abnormal muscle hypertrophy of myofascial trigger points via TNF-α/ NF-κB signaling pathway in rats80
Icotinib derivatives as tyrosine kinase inhibitors with anti-esophageal squamous carcinoma activity80
Dihydroarteannuin Ameliorates Collagen-Induced Arthritis Via Inhibiting B Cell Activation by Activating the FcγRIIb/Lyn/SHP-1 Pathway80
Neuroregeneration of injured peripheral nerve by fraction B of catfish epidermal secretions through the reversal of the apoptotic pathway and DNA damage80
Function-Wise Dual-Omics analysis for radiation pneumonitis prediction in lung cancer patients80
Optimization of gabapentin dosage in pediatric patients with renal impairment: a physiologically based pharmacokinetic modeling approach80
Emerging Nanotheranostics for 5-Fluorouracil in Cancer Therapy: A Systematic Review on Efficacy, Safety, and Diagnostic Capability79
Optimizing antidotal treatment with the oral HSP90 inhibitor TAS-116 against hydrochloric acid-induced pulmonary fibrosis in mice78
Cannabidiol for neurodegenerative disorders: A comprehensive review78
Accidental cannabis intoxication in two young children: clinical presentation and toxicokinetics - a case series78
Ex vivo perfusion model of mouse liver and its application to analyze the effects of OCT1 deficiency77
Human matters in asthma: Considering the microbiome in pulmonary health77
Interaction and potential mechanisms between atorvastatin and voriconazole, agents used to treat dyslipidemia and fungal infections77
Discovery of novel benzylquinazoline molecules as p97/VCP inhibitors77
Exploration of the Mechanism of Salvianolic Acid for Injection Against Ischemic Stroke: A Research Based on Computational Prediction and Experimental Validation77
Evaluation of standard use of intravenous infusion in 25 general hospitals in Shanxi province based on factor analysis and cluster analysis77
The therapeutic effect of curcumin in metabolic dysfunction-associated steatotic liver disease: a systematic review and meta-analysis of animal studies76
Safety profile of lutein-based blue dyes and surgical lights75
Protective effects of insulin on dry eye syndrome via TLR4/NF-κB pathway: based on network pharmacology and in vitro experiments validation75
Unknown adverse drug reactions from spontaneous reports in a hospital setting: characterization, follow-up, and contribution to the pharmacovigilance system75
Editorial: Big data for biomedical research of inflammatory diseases74
Serum metabolomics identifies novel prognostic biomarkers in amanita poisoning74
Is it possible to diagnose therapeutic adherence in mild cognitive impairment and dementia patients in clinical practice?74
Strategies for salvage therapy post CAR-T therapy failure in refractory/relapsed multiple myeloma patients74
The efficacy of aminosalicylates in acute radiation enteritis: a systematic review and meta-analysis74
An economic evaluation of knee osteoarthritis treatments in Thailand74
Functional characterization of the α1-adrenoceptor in adult male rat locus coeruleus neurons ex vivo72
Activation of EP4 alleviates AKI-to-CKD transition through inducing CPT2-mediated lipophagy in renal macrophages72
Acute myocardial infarction induced by avatrombopag: a case report72
8 specific Chinese herbal injections combined with chemotherapy for breast cancer: a systematic review and network meta-analysis of comparative safety and efficacy72
Machine learning methods for propensity and disease risk score estimation in high-dimensional data: a plasmode simulation and real-world data cohort analysis71
Pterostilbene attenuates lung ischemia-reperfusion injury: integrative insights from network pharmacology, molecular dynamics, and experimental validation71
Polygala tenuifolia and Acorus tatarinowii in the treatment of Alzheimer’s disease: a systematic review and meta-analysis71
Prospective population pharmacokinetic study of tacrolimus in adult recipients early after liver transplantation: A comparison of Michaelis-Menten and theory-based pharmacokinetic models71
The Amazonian kambô frog Phyllomedusa bicolor (Amphibia: Phyllomedusidae): Current knowledge on biology, phylogeography, toxinology, ethnopharmacology and medical aspects71
Pharmacist-Urologist Collaborative Management Improves Clinical Outcomes in Patients With Castration-Resistant Prostate Cancer Receiving Enzalutamide70
Ginseng and Polygonum multiflorum formula protects brain function in Alzheimer’s disease70
Recent clinical evidence on nutrition, novel pharmacotherapy, and vaccination in inflammatory bowel diseases70
Doxycycline for the treatment of breast cancer-related lymphedema69
Abhraka Bhasma (mica based nanomedicine): an ayurvedic herbomineral perspective in breast cancer management69
Investigating the therapeutic potential of hesperidin targeting CRISP2 in intervertebral disc degeneration and cancer risk mitigation69
Efficacy, safety and mechanism of Honghua Xiaoyao Pill in the treatment of peri-menopausal syndrome: A study protocol for a randomized controlled trial69
Traditional Chinese Medicine: A Class of Potentially Reliable Epigenetic Drugs69
Curcumin as a potential therapeutic agent for Parkinson’s disease: a systematic review69
Barriers to prescribing and insurance approval of SGLT2 inhibitors for heart failure: a mixed-methods study in Jordan69
Integrating single-cell RNA-seq, bulk RNA-seq and network pharmacology reveals protective effect of salidroside in peritoneal dialysis-associated peritoneal fibrosis68
Model-informed precision dosing in vancomycin treatment68
The electrocardiographic, hemodynamic, echocardiographic, and biochemical evaluation of treatment with edaravone on acute cardiac toxicity of aluminum phosphide68
Wendan decoction in the treatment of nonalcoholic fatty liver disease: A systematic review and meta-analysis68
A machine learning model integrating gut microbiota biomarkers for predicting neurological recovery after cerebral hypoxia-ischemia: a single-center study augmented with public data68
Fuyuan decoction prevents nasopharyngeal carcinoma metastasis by inhibiting circulating tumor cells/ endothelial cells interplay and enhancing anti-cancer immune response67
Targeting cancer with delphinidin: from molecular insights to therapeutic implications67
Calycosin induces autophagy and apoptosis via Sestrin2/AMPK/mTOR in human papillary thyroid cancer cells67
A minimal PBPK model to accelerate preclinical development of drugs against tuberculosis66
T-type calcium channel modulation by hydrogen sulfide in neuropathic pain conditions66
Traditional Chinese medicine in the prevention of diabetes mellitus and cardiovascular complications: mechanisms and therapeutic approaches66
Correction: Efficacy and safety of oral Chinese medicine combined with chemotherapy: a systematic review and network meta-analysis66
SARS-CoV-2 infection dysregulates the expression of clinically relevant drug metabolizing enzymes in Vero E6 cells and membrane transporters in human lung tissues66
Ivarmacitinib reduces the need for adding/escalating medications in moderate-to-severe rheumatoid arthritis patients: a post hoc analysis from a phase III trial66
The brief overview, antivirus and anti-SARS-CoV-2 activity, quantitative methods, and pharmacokinetics of cepharanthine: a potential small-molecule drug against COVID-1966
Sishen Pill and its active phytochemicals in treating inflammatory bowel disease and colon cancer: an overview65
Potential mechanisms of Lian-Zhi-Fan solution for TNBS-induced ulcerative colitis in rats via a metabolomics approach65
Effects of Dexmedetomidine on Immune Cells: A Narrative Review65
Does preterm birth increase the initiation of antidepressant use during the postpartum? A population-based investigation64
Glutathione and neurodegenerative diseases: immunopharmacological implications64
Decoding the heterogeneity of liver-resident macrophages in chronic liver diseases: therapeutic responses to immunomodulatory strategies63
Biomimetic astragaloside-IV-loaded mesoporous silica nanoparticles for treatment of dilated cardiomyopathy63
Autophagy plays an essential role in ultraviolet radiation-driven skin photoaging63
Dysregulated neuromodulation in the anterior cingulate cortex in chronic pain63
Exploring the mechanism of baicalein on choroid melanoma based on network pharmacology, transcriptomics and experimental verification63
Effect of age and ICU types on mortality in invasive mechanically ventilated patients with sepsis receiving dexmedetomidine: a retrospective cohort study with propensity score matching62
Mechanistic study on the restoration of intestinal barrier integrity and alleviation of inflammatory bowel disease by rhynchophylline via the AhR-NR4A1 pathway62
Clinical study of ganshuang granule combined with tenofovir in the treatment of chronic hepatitis B complicated with nonalcoholic fatty liver disease62
Chaihu Longgu Muli Decoction inhibits chronic stress-induced lung cancer epithelial-mesenchymal transition process by suppressing Rap1/ERK signal pathway62
Circular RNAs in ferroptosis: regulation mechanism and potential clinical application in disease62
Case Report: Botulism associated with cosmetic BoNT-A injections: respiratory failure and multidrug-resistant infection as emerging clinical challenges61
Hypoglycemic effects of dendrobium officinale leaves61
Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether‐à‐go‐go–Related Gene and Cav1.261
Pre-clinical toxicity assessment of Artemisia absinthium extract-loaded polymeric nanoparticles associated with their oral administration61
Chinese herbal compound for multidrug-resistant or extensively drug-resistant bacterial pneumonia: a meta-analysis and trial sequential analysis with association rule mining to identify core herb comb61
Exploring HSP90α and hs-CRP using AI models to predict prognosis in advanced hepatocellular carcinoma treated with PD-1 inhibitors and targeted therapy61
Hepatoprotective Efficacy and Interventional Mechanism of Qijia Rougan Decoction in Liver Fibrosis61
First-in-human study to assess the safety, tolerability, pharmacokinetics and immunogenicity of DS002, an anti-nerve growth factor monoclonal antibody61
Natural product extracts for ischemic stroke: a methodological evaluation and meta-epidemiological analysis60
A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects60
Genome-wide CRISPR screen identified NEK6 as a determinant of sensitivity to CDK4/6 inhibitor in endometrial cancer60
Preventive effect of small molecule active substances on septic cardiomyopathy after abdominal trauma: a systematic review and meta-analysis60
Donor lymphocyte infusion combined with azacitidine after allogeneic HSCT in pediatric AML: a single-center retrospective analysis60
Correction: The antipsychotics functional index (AFI) in schizophrenia59
Editorial: Novel therapeutics for urological cancers59
Editorial: Metabolic dysfunction-associated fatty liver disease (MAFLD): innovative management strategies using herbal medicines59
Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity59
Effect of herbal medicine Bojungikgi-tang on gut microbiome and symptoms in anorexic patients with atopic dermatitis: a randomized controlled trial59
Comparative safety profiles of spironolactone, eplerenone, and finerenone: a pharmacovigilance study based on FAERS data from 2004 to 202459
The therapeutic potential of natural metabolites in targeting endocrine-independent HER-2-negative breast cancer59
Corrigendum: Comparison of the effectiveness and safety of perampanel and oxcarbazepine as monotherapy in children and adolescents with newly diagnosed focal epilepsy58
Erratum: Isoflurane-lipid emulsion injection as an anticonvulsant and neuroprotectant treatment for nerve agent exposure58
Wenshen-Jianpi prescription, a Chinese herbal medicine, improves visceral hypersensitivity in a rat model of IBS-D by regulating the MEK/ERK signal pathway58
Corrigendum: Shu-Xie decoction alleviates oxidative stress and colon injury in acute sleep-deprived mice by suppressing p62/KEAP1/NRF2/HO1/NQO1 signaling58
Drug-related problems among transfusion-dependent thalassemia patients: A real-world evidence study58
Pemetrexed sensitizes cisplatin therapy by inducing ferroptosis in NSCLC cells58
Corrigendum: Xenon attenuated neonatal lipopolysaccharide exposure induced neuronal necroptosis and subsequently improved cognition in juvenile rats58
Inhibitory effects of calcium channel blockers nisoldipine and nimodipine on ivacaftor metabolism and their underlying mechanism58
Erratum: Exploring the pharmacological action mechanism of Ligusticum Chuanxiong-Piper Longum couplet medicines on the treatment of migraine based on network pharmacology58
Corrigendum: Editorial: The mechanisms of action of anti-SARS-CoV-2 drugs58
Effect of corticosteroids combined with cyclophosphamide or mycophenolate mofetil therapy for IgA nephropathy with stage 3 or 4 chronic kidney disease: A retrospective cohort study57
Harnessing the power of natural alkaloids: the emergent role in epilepsy therapy57
Adverse events in different administration routes of amiodarone: a pharmacovigilance study based on the FDA adverse event reporting system57
Buyang Huanwu Decoction alleviates cerebral ischemic injury through modulating caveolin-1-mediated mitochondrial quality control57
Factors associated with medication adherence among children with rheumatic diseases57
Efficacy and safety of sequential immunosuppressive treatment for severe IgA nephropathy: A retrospective study57
Protective effects of curcumin against chemical-induced toxicity in the male reproductive system: a systematic review57
Efficacy analysis of splint combined with platelet-rich plasma in the treatment of temporomandibular joint osteoarthritis57
Pre- and post-chemotherapy spermatogenesis in male patients with malignant bone and soft tissue tumors56
Discovery of a novel natural compound, vitekwangin B, with ANO1 protein reduction properties and anticancer potential56
Evaluating cardiac disorders associated with triazole antifungal agents based on the US Food and Drug Administration Adverse Event reporting system database56
Artemisinin and its derivatives: all-rounders that may prevent the progression from lung injury to lung cancer56
Long-term administration of bumetanide improve functional recovery after spinal cord injury in rats56
Radiosensitization effect of iridium (III) complex on lung cancer cells via mitochondria apoptosis pathway56
Modulating mitochondria with natural extract compounds: from bench to clinical therapeutic opportunities for COPD56
Identification of potential quality markers of Zishen Yutai pill based on spectrum–effect relationship analysis56
Network pharmacology, molecular docking, and experimental validation to explore the potential mechanism of Long Mu Qing Xin mixture for the treatment of attention deficit hyperactivity disorder56
Natural killer cell-related prognosis signature predicts immune response in colon cancer patients56
Potential of resveratrol in the treatment of interstitial lung disease56
Antisense Oligonucleotide-Based Therapy on miR-181a-5p Alleviates Cartilage Degradation of Temporomandibular Joint Osteoarthritis via Promoting SIRT156
Water extract of cacumen platycladi promotes hair growth through the Akt/GSK3β/β-catenin signaling pathway56
Evaluation of trimetazidine in alleviating paclitaxel-induced peripheral neuropathy in breast cancer patients: a randomized controlled trial56
Integrated network pharmacology and experimental analysis unveil multi-targeted effect of 18α- glycyrrhetinic acid against non-small cell lung cancer56
Gegen Qinlian decoction prevents post-ERCP pancreatitis by regulating NLRP3 inflammasome-mediated pyroptosis55
CDFA: Calibrated deep feature aggregation for screening synergistic drug combinations55
Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients55
The forensic aspects of suicide and neurotrophin factors: a research study55
Unlocking the secrets of glucose metabolism reprogramming: the role in pulmonary diseases55
Beta-blocker exposure and survival outcomes in patients with advanced pancreatic ductal adenocarcinoma: a retrospective cohort study (BETAPANC)55
Nephroprotective potential of Polyalthia longifolia roots against vancomycin-induced renal toxicity in experimental animals55
Efficacy and safety of Abelmoschus moschatus capsules combined with tripterygium glycoside tablets on diabetic nephropathy: A systematic review and meta-analysis55
Network pharmacology and experimental verification-based strategy to explore the underlying mechanism of Liu Jun An Wei formula in the treatment of gastrointestinal reactions caused by chemotherapy fo55
Traditional Chinese Medicine in Treating Primary Podocytosis: From Fundamental Science to Clinical Research54
Ginsenoside Rb1 improves intestinal aging via regulating the expression of sirtuins in the intestinal epithelium and modulating the gut microbiota of mice54
Potential Treat-to-Target Approach for Methamphetamine Use Disorder: A Pilot Study of Adenosine 2A Receptor Antagonist With Positron Emission Tomography54
Efficacy and safety of Chinese medicine injections in combination with docetaxel and cisplatin for non-small cell lung cancer: a network meta-analysis54
Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation54
Comparative efficacy and acceptability of pharmacotherapies for postpartum depression: A systematic review and network meta-analysis54
Quantum chemical calculations of nitrosamine activation and deactivation pathways for carcinogenicity risk assessment54
Using Drosophila melanogaster as a suitable platform for drug discovery from natural products in inflammatory bowel disease54
Leveraging AI to automate detection and quantification of extrachromosomal DNA to decode drug responses54
Multi-omic analysis reveals that Bacillus licheniformis enhances pekin ducks growth performance via lipid metabolism regulation53
Efficacy and safety of oral minoxidil in the treatment of alopecia: a single-arm rate meta-analysis and systematic review53
Individualized, dynamic, and full-course vancomycin dosing prediction: a study on the customized dose model53
Multitarget mechanisms of the herb pair Achyranthes bidentata and Paeonia lactiflora Pall. in ameliorating hypertensive cardiomyopathy: combining network pharmacology and functional exploration53
Typing characteristics of metabolism-related genes in osteoporosis53
Chrysophanol promotes M2 polarization and inhibits M1 polarization through the NF-κB signaling pathway to attenuate sepsis-associated acute kidney injury53
Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models52
Ginsenosides, potential TMPRSS2 inhibitors, a trade-off between the therapeutic combination for anti-PD-1 immunotherapy and the treatment of COVID-19 infection of LUAD patients52
Side-stepping the guardian of the genome: current cancer therapeutics targeting mutant p5352
Hemoglobin α-derived peptides VD-hemopressin (α) and RVD-hemopressin (α) are involved in electroacupuncture inhibition of chronic pain52
Evaluating a multifaceted stewardship intervention on proton pump inhibitor utilization: an interrupted time-series analysis of prescribing patterns in a northwest Chinese hospital52
Myristic acid beneficially modulates intervertebral disc degeneration by preventing endplate osteochondral remodeling and vertebral osteoporosis in naturally aged mice52
Licorice attenuates cisplatin-induced hepatotoxicity by alleviating endoplasmic reticulum stress and apoptosis52
Pharmacogenomics of risperidone in autism spectrum disorder: a minireview52
Protective effect and mechanism of Qingfei Paidu decoction on myocardial damage mediated by influenza viruses52
Methotrexate-conjugated zinc oxide nanoparticles exert a substantially improved cytotoxic effect on lung cancer cells by inducing apoptosis52
Potential role of extracellular granzyme B in wet age-related macular degeneration and fuchs endothelial corneal dystrophy52
Healthcare professional perspectives on medication challenges in the post-stroke patient52
Discovering the potential active ingredients of Qi-Yu-San-Long decoction for anti-oxidation, inhibition of non-small cell lung cancer based on the spectrum-effect relationship combined with chemometri51
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