OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Immunology is 122. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Editorial: Molecular Pathways Controlling Epithelial Inflammation in the Gut	674
Case Report: Refractory Cytopenia With a Switch From a Transient Monosomy 7 to a Disease-Ameliorating del(20q) in a NHEJ1-Deficient Long-term Survivor	451
Editorial: The fundamental biology of basophils in health and disease	375
Editorial: Insights in microbial immunology: 2022	322
Inhibition of tumor necrosis factor receptor 1 and the risk of periodontitis	310
Editorial: Cell network in antitumor immunity of pediatric and adult solid tumors	301
Fc receptors act as innate immune receptors during infection?	284
Case report: Brain metastasis necrosis with immune checkpoint inhibitors plus chemotherapy for advanced non-small cell lung cancer	281
Cytokine and chemokine multiplex analysis-based exploration for potential treatment and prognostic prediction in large-vessel vasculitis: A preliminary observational study	277
Spatiotemporal quantitative microRNA-155 imaging reports immune-mediated changes in a triple-negative breast cancer model	265
A 4-Benzene-Indol Derivative Alleviates LPS-Induced Acute Lung Injury Through Inhibiting the NLRP3 Inflammasome	263
Exploring the ROS reduction strategies in chronic lupus management	253
Application of JAK inhibitors in paradoxical reaction through immune-related dermatoses	244
Effect of autologous dendritic cell cytokine-induced killer on refractory metastatic colorectal cancer: a matched case–control comparative study	237
Single-cell RNA sequencing reveals cell type-specific immune regulation associated with human neuromyelitis optica spectrum disorder	237
Editorial: Emerging Roles for Type 2-Associated Cells and Cytokines in Cancer Immunity	237
Editorial: Molecular drivers of immunothrombosis	229
The NF-κB RelA transcription factor is not required for CD8+ T-cell function in acute viral infection and cancer	224
Maintenance therapy of low-dose nivolumab, S-1, and leucovorin in metastatic pancreatic adenocarcinoma with a germline mutation of MSH6: A case report	221
Identification of cerebrospinal fluid biomarker candidates for anti-N-methyl-D-aspartate receptor encephalitis: High-throughput proteomic investigation	215
Biomarkers for prediction of CAR T therapy outcomes: current and future perspectives	211
Computational identification and experimental verification of a novel signature based on SARS-CoV-2–related genes for predicting prognosis, immune microenvironment and therapeutic strategies in lung a	209
Construction and validation of a machine learning-based nomogram to predict the prognosis of HBV associated hepatocellular carcinoma patients with high levels of hepatitis B surface antigen in primary	208
Nucleoprotein of a Rice Rhabdovirus Serves as the Effector to Attenuate Hemolymph Melanization and Facilitate Viral Persistent Propagation in its Leafhopper Vector	200
Increased interleukin-9 and Th9 cells in patients with refractory Graves’ disease and interleukin-9 polymorphisms are associated with autoimmune thyroid diseases	199

The intricate dance of non-coding RNAs in myasthenia gravis pathogenesis and treatment	198
Efficacy and safety of BVAC-C in HPV type 16- or 18–positive cervical carcinoma who failed 1st platinum-based chemotherapy: a phase I/IIa study	197
Is the exquisite specificity of lymphocytes generated by thymic selection or due to evolution?	196
Programmed cell death-ligand 2: new insights in cancer	196
Prevalence of resistance-associated viral variants to the HIV-specific broadly neutralising antibody 10-1074 in a UK bNAb-naïve population	194
Editorial: Understanding anti-trypanosomatid immune responses: The key to developing protective strategies against them	191
Protective Effect Against Toxoplasmosis in BALB/c Mice Vaccinated With Recombinant Toxoplasma gondii MIF, CDPK3, and 14-3-3 Protein Cocktail Vaccine	190
Differences in F pocket impact on HLA I genetic associations with autoimmune diabetes	185
Modification of Extracellular Matrix by the Product of DHA Oxidation Switches Macrophage Adhesion Patterns and Promotes Retention of Macrophages During Chronic Inflammation	184
Immunometabolic actions of trabectedin and lurbinectedin on human macrophages: relevance for their anti-tumor activity	184
Immunostimulation of Asian elephant (Elephas maximus) blood cells by parapoxvirus ovis and CpG motif-containing bacterial plasmid DNA upregulates innate immune gene expression	184
B cell intrinsic and extrinsic factors impacting memory recall responses to SRBC challenge	180
Effects of chemotherapy and immunotherapy on microbial diversity in TME and engineered bacterial-mediated tumor therapy	177
IMPROVE: a feature model to predict neoepitope immunogenicity through broad-scale validation of T-cell recognition	177
Favorable response to PD-1 inhibitor plus chemotherapy as first-line treatment for metastatic follicular dendritic cell sarcoma of the spleen: a case report	175
The relation of the frequency and functional molecules expression on plasmacytoid dendritic cells to postpartum hepatitis in women with HBeAg-positive chronic hepatitis B virus infection	173
Positive regulators of T cell functions as predictors of prognosis and microenvironment characteristics of low-grade gliomas	171
Long term complete response of advanced hepatocellular carcinoma to glypican-3 specific chimeric antigen receptor T-Cells plus sorafenib, a case report	170
Identification of key genes and imbalance of immune cell infiltration in immunoglobulin A associated vasculitis nephritis by integrated bioinformatic analysis	168
Case Report: Local Cytokine Release Syndrome in an Acute Lymphoblastic Leukemia Patient After Treatment With Chimeric Antigen Receptor T-Cell Therapy: A Possible Model, Literature Review and Perspecti	168
CHI3L1 in the CSF is a potential biomarker for anti-leucine-rich glioma inactivated 1 encephalitis	167
Retrospective identification of the first cord blood–transplanted severe aplastic anemia in a STAT1-associated chronic mucocutaneous candidiasis family: case report, review of literature and pathophys	166
Systematic computer-aided disulfide design as a general strategy to stabilize prefusion class I fusion proteins	166
Evaluation of the potential food allergy risks of human lactoferrin expressed in Komagataella phaffii	165
IL-4-Responsive B Cells Are Detrimental During Chronic Tuberculosis Infection in Mice	164
Editorial: Liver transplantation for liver cancer in the era of transplant oncology: accurate diagnosis and treatment	163
Intramuscular vaccination against SARS-CoV-2 transiently induces neutralizing IgG rather than IgA in the saliva	163
Oxytocin and Related Peptide Hormones: Candidate Anti-Inflammatory Therapy in Early Stages of Sepsis	163
Severe Adaptive Immune Suppression May Be Why Patients With Severe COVID-19 Cannot Be Discharged From the ICU Even After Negative Viral Tests	163
Granzyme A Produced by γ9δ2 T Cells Activates ER Stress Responses and ATP Production, and Protects Against Intracellular Mycobacterial Replication Independent of Enzymatic Activity	162
Immune-mediated inflammatory diseases with chronic excess of serum interleukin-18	162
Editorial: The mechanism and novel strategies of overcoming resistance of hematological malignancies to CAR-T cell killing	161
Identification and Characterization of a Master Transcription Factor of Th1 Cells, T-bet, Within Flounder (Paralichthys olivaceus)	159
CXCL8 Associated Dendritic Cell Activation Marker Expression and Recruitment as Indicators of Favorable Outcomes in Colorectal Cancer	158
Human CD4 T Cells From Thymus and Cord Blood Are Convertible Into CD8 T Cells by IL-4	158
Indoleamine 2, 3 Dioxygenase 1 Impairs Chondrogenic Differentiation of Mesenchymal Stem Cells in the Joint of Osteoarthritis Mice Model	157
Clinical Utility of Whole Exome Sequencing and Targeted Panels for the Identification of Inborn Errors of Immunity in a Resource-Constrained Setting	156
Recombinant Full-Length Hepatitis C Virus E1E2 Dimer Elicits Pangenotypic Neutralizing Antibodies	156
Metabolic heterogeneity caused by HLA-DRB1*04:05 and protective effect of inosine on autoimmune hepatitis	156
COVID-19 pandemic: A multidisciplinary perspective on the pathogenesis of a novel coronavirus from infection, immunity and pathological responses	156
Putative Immunological Functions of Inducible Skin-Associated Lymphoid Tissue in the Context of Mucosa-Associated Lymphoid Tissue	156
Editorial: The Role of Mast Cells in Immediate Hypersensitivity Reactions	155
Editorial: Improvement of melanoma immune checkpoint blockade therapy with potential combinatorial regiments	155
Immunological characterization and function analysis of L-type lectin from spotted knifejaw, Oplegnathus punctatus	153
T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation	153
Peripheral T lymphocyte and immunocyte subset dynamics: markers of neoadjuvant therapy outcomes in esophageal squamous cell carcinoma	153
Case Report: CD19 and CD20 monoclonal antibodies with sequential chemotherapy for refractory acute B-lymphocytic leukemia in children	152
Commentary: An In Silico – In Vitro Pipeline Identifying an HLA-A*02:01+ KRAS G12V+ Spliced Epitope Candidate for a Broad Tumor-Immune Response in Cancer Patients	150
Early Blood Transfusion After Kidney Transplantation Does Not Lead to dnDSA Development: The BloodIm Study	150
Csf2ra deletion attenuates acute lung injuries induced by intratracheal inoculation of aerosolized ricin in mice	149

Editorial: Community series in immunometabolic mechanisms underlying the severity of COVID-19, volume II	147
Preclinical proof of concept of a tetravalent lentiviral T-cell vaccine against dengue viruses	146
Editorial: Mucosal immunity to HIV and SARS-CoV-2 infection and vaccination	146
Baseline Characteristics of Mitochondrial DNA and Mutations Associated With Short-Term Posttreatment CD4+T-Cell Recovery in Chinese People With HIV	146
Coexistence of Primary Sjögren’s Syndrome and Autoimmune Gastritis With Pernicious Anemia and Subacute Combined Degeneration of the Spinal Cord: Case Report and Literature Review	146
Editorial: Neuroinflammation and Neuroautoimmunity in Peripheral Neuropathies: Old Players, New Roles	145
Editorial: Immune Cell Migration in Health and Disease	144
Exploring type I interferon pathway: virulent vs. attenuated strain of African swine fever virus revealing a novel function carried by MGF505-4R	143
Potential for the development of Taraxacum mongolicum aqueous extract as a phytogenic feed additive for poultry	141
Role of differentiated embryo-chondrocyte expressed gene 2 in immunity	139
Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept	138
The impact of CD3ζ ITAM multiplicity and sequence on CAR T-cell survival and function	138
MUC2 expression modulates immune infiltration in colorectal cancer	137
Active ingredients of traditional Chinese medicine inhibit NOD-like receptor protein 3 inflammasome: a novel strategy for preventing and treating heart failure	137
Novel immunochromatographic test for rapid detection of anti-factor H autoantibodies with an assessment of its clinical relevance	137
From actinic keratosis to cutaneous squamous cell carcinoma: the key pathogenesis and treatments	136
Editorial: Immunology of food-borne parasites: recent progress and future advances	135
A new paradigm for cancer immunotherapy: targeting immunogenic cell death-related noncoding RNA	133
Associations between neutrophil percentage to albumin ratio and rheumatoid arthritis versus osteoarthritis: a comprehensive analysis utilizing the NHANES database	132
Dual-release hydrocortisone treatment improves serum and peripheral blood mononuclear cell inflammatory and immune profiles in patients with autoimmune primary adrenal insufficiency	132
The XIAP inhibitor AZD5582 improves the treatment effect of microwave ablation on hepatocellular carcinoma	132
Broadening horizons: research on ferroptosis in lung cancer and its potential therapeutic targets	130
Unveiling immunogenic characteristics and neoantigens in endometrial cancer with POLE hotspot mutations for improved immunotherapy	130
Antiviral therapy can effectively suppress irAEs in HBV positive hepatocellular carcinoma treated with ICIs: validation based on multi machine learning	129
Plasma IL-17A is increased in patients with critical MIS-C and associated to in-hospital mortality	129
Cordyceps militaris solid medium extract alleviates lipopolysaccharide-induced acute lung injury via regulating gut microbiota and metabolism	128
Infectious outcomes of a standardized subcutaneous immunoglobulin dose reduction strategy in primary immune deficiencies amid global shortage	128
Aspartate aminotransferase to platelet ratio correlates with poor prognosis and metabolic alterations in Dabie bandavirus infection	128
A practical guide to FAIR data management in the age of multi-OMICS and AI	128
A new weapon: the application of tumor vaccines based on extracellular exosomal heat shock proteins in immunotherapy	127
Exploring the effects of dietary methionine supplementation on European seabass mucosal immune responses against Tenacibaculum maritimum	127
Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism	127
Effect of trace elements and nutrients on 21 autoimmune diseases: a Mendelian randomization study	127
Identification of circulating Tfh/Th subsets as a biomarker of developed hospital-acquired pneumonia	127
Islet organoids: a new hope for islet transplantation in diabetes	126
Epithelial-mesenchymal transition in asthma: its role and underlying regulatory mechanisms	125
Commentary: Identification of Genes Linking Natural Killer Cells to Apoptosis in Acute Myocardial Infarction and Ischemic Stroke	124
The first successful bone marrow transplantation in Vietnam for a young Vietnamese boy with chronic granulomatous disease: a case report	124
Antibody landscape of C57BL/6 mice cured of B78 melanoma via a combined radiation and immunocytokine immunotherapy regimen	124
Editorial: The mechanism of metabolic immune microenvironment, inflammation and blood milk barrier in mastitis	124
Editorial: Community series in translational insights into mechanisms and therapy of organ dysfunction in sepsis and trauma - volume III	123
Comparative long-term outcomes of pembrolizumab plus chemotherapy versus pembrolizumab monotherapy as first-line therapy for metastatic non-small-cell lung cancer: a systematic review and network meta	123
Case report: eosinophilic myocarditis in hypereosinophilic syndrome: a journey to heart transplantation	123
Editorial: Recent Advances in Basic and Translational Osteoimmunology	122
Distinct anti-NP, anti-RBD and anti-Spike antibody profiles discriminate death from survival in COVID-19	122
Vaccinating women previously treated for human papillomavirus-related cervical precancerous lesions is highly cost-effective in China	122
Metabolism and immune memory in invertebrates: are they dissociated?	122