Frontiers in Immunology

Papers
(The H4-Index of Frontiers in Immunology is 127. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
The transcription factor TSHZ3 promotes tumor immunosuppression and inhibits metastasis in lung adenocarcinoma541
Systematic pan-cancer analysis identifies PKNOX1 as a potential prognostic and immunological biomarker and its functional validation488
Editorial: Interaction of cell subtypes in tumor microenvironment, and implications for immunotherapy486
Editorial: Preclinical macaque models of viral diseases442
A conserved motif in the immune-subdominant RAP-1 related antigen of Babesia bovis contains a B-cell epitope recognized by antibodies from protected cattle403
Interpreting high levels of unfolded Von Willebrand Factor in patients with the antiphospholipid syndrome402
Influence of Type I Interferons in Gammaherpesvirus-68 and Its Influence on EAE Enhancement393
The potential role of cfDNA-related innate immune responses in postoperative bone loss after alveolar bone grafting387
Paired Donor and Recipient Immunophenotyping in Allogeneic Hematopoietic Stem Cell Transplantation: A Cellular Network Approach355
Case report: A case of duodenal adenocarcinoma achieving significantly long survival treating with immune checkpoint inhibitors and chemotherapy without positive biomarkers353
The suppressive role of GLS in radiosensitivity and irradiation-induced immune response in LUAD: integrating bioinformatics and experimental insights350
Differential regulation of heparan sulfate biosynthesis in fibroblasts cocultured with normal vs. cancerous prostate cells347
Editorial: Host-virus interaction at the omics and ecology levels347
A conserved element in the first intron of Cd4 has a lineage specific, TCR signal-responsive, canonical enhancer function that matches the timing of cell surface CD4 upregulation required to prevent l342
Kidney transplant outcomes in HLA desensitized patients with pretransplant CDC and/or FCM positive crossmatches327
Characterization of immune features and immunotherapy response in subtypes of hepatocellular carcinoma based on mitophagy322
Editorial: Broadening our view on nucleic acid sensing: novel sensors, signaling pathways, and involvement in non-infectious diseases316
Aberrant glycosylation patterns as potential biomarkers for diagnosis and disease progression in bullous pemphigoid313
Editorial: Novel Platform for Antigen Delivery to Dendritic Cells for Immunotherapy313
Role of RGC-32 in multiple sclerosis and neuroinflammation – few answers and many questions304
Editorial: Understanding bladder tumor microenvironment to optimize immunotherapy302
Editorial: Exploring cardiovascular and cerebrovascular diseases interaction with inflammation: biomarkers, drug targets, and personalized treatments through multi-omics data integration296
Effects of rumen cannulation combined with different pre-weaning feeding intensities on the intestinal, splenic and thymic immune system in heifer calves several month after surgery288
Soluble Fc Receptor for IgM in Sera From Subsets of Patients With Chronic Lymphocytic Leukemia as Determined by a New Mouse Monoclonal Antibody275
Characterization of novel anoikis-related genes as prognostic biomarkers and key determinants of the immune microenvironment in esophageal cancer266
Unveiling B7/CD28 family proteins in hepatocellular carcinoma: insights into communication and prognostic significance264
Editorial: Nanoparticles for cancer immunotherapy: from basics to clinics257
SARS-CoV-2 strains and clinical profiles of COVID-19 patients in a Southern Brazil hospital254
Transcriptome analysis revealed the roles of long non-coding RNA and mRNA in the bursa of Fabricius during pigeon (Columba livia) development254
Genetic deletion of HVEM in a leukemia B cell line promotes a preferential increase of PD-1- stem cell-like T cells over PD-1+ T cells curbing tumor progression252
Efficacy and safety of camrelizumab combined with albumin-bound paclitaxel as third- or later-line regimen in patients with advanced non-small cell lung cancer248
Editorial: Targeting key cellular signaling network for cancer chemotherapy and immunotherapy245
Case Report: Real NPSLE? A patient with systemic sclerosis overlapping systemic lupus erythematosus presenting as epilepsy245
Cardiovascular impairment in Shiga-toxin-2-induced experimental hemolytic–uremic syndrome: a pilot study239
Editorial: Gasdermins in the defense against pathogens231
Dynamics of IgG antibody response against Plasmodium antigens among Nigerian infants and young children228
Lin28 regulates thymic growth and involution and correlates with MHCII expression in thymic epithelial cells222
Editorial: Molecular and cellular control of B cell responses: germinal center and extrafollicular responses for cellular outputs214
CHI3L1 in the CSF is a potential biomarker for anti-leucine-rich glioma inactivated 1 encephalitis213
Editorial: Crosstalk between cell death, oxidative stress, and immune regulation211
Editorial: Liver transplantation for liver cancer in the era of transplant oncology: accurate diagnosis and treatment205
Editorial: Immunoglobulin Glycosylation Analysis: State-of-the-Art Methods and Applications in Immunology202
A specific immune signature for predicting the prognosis of glioma patients with IDH1-mutation and guiding immune checkpoint blockade therapy201
Prognostic models for predicting postoperative recurrence in Crohn’s disease: a systematic review and critical appraisal199
Study protocol: a prospective single-center study for non-invasive biomonitoring of renal complications in cancer patients treated with immune checkpoint inhibitors198
Salivary interleukin-17A and interferon-γ levels are elevated in children with food allergies in China198
Patrolling monocytes mediate virus neutralizing IgG effector functions: beyond neutralization capacity197
Determining the Optimal (Neo)Adjuvant Regimen for Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Regarding Survival Outcome: A Network Meta-Analysis197
Case Report: A myasthenia gravis patient complicated with renal failure was effectively treated with efgartigimod196
Unveiling immunogenic characteristics and neoantigens in endometrial cancer with POLE hotspot mutations for improved immunotherapy194
SIRGs score may be a predictor of prognosis and immunotherapy response for esophagogastric junction adenocarcinoma191
Induction chemoradiotherapy achieves long-term recurrence-free survival in locally advanced pulmonary lymphoepithelioma-like carcinoma: a case report and literature review190
Serum adipsin levels in rheumatic diseases: defining its role in disease activity and progression in rheumatoid arthritis and axial spondyloarthritis187
The first successful bone marrow transplantation in Vietnam for a young Vietnamese boy with chronic granulomatous disease: a case report185
IL-21 is required for the maintenance and pathogenesis of murine Vγ4+ IL-17-producing γδT cells183
Ribosome biogenesis-related gene signature predicts prognosis and immune landscape in glioma and identifies UTP20 as a therapeutic target183
Atherosclerotic cardiovascular disease and mortality in a cohort of patients with rheumatoid arthritis: a prospective study investigating microRNAs as predictors of atherosclerosis and mortality180
Proteomic Signatures of Monocytes in Hereditary Recurrent Fevers179
Phase 2 trial (NCI-COTC030) of adjuvant inhaled recombinant human IL-15 combined with amputation and adjuvant chemotherapy in dogs with appendicular osteosarcoma178
Editorial: Understanding anti-trypanosomatid immune responses: The key to developing protective strategies against them178
The type of pathogen is associated with organ failure and legacy dysfunction in patients with sepsis177
Case Report: Suspected Case of Brucella-Associated Immune Reconstitution Inflammatory Syndrome175
Developmental trajectory of long-lived plasma cells172
Case Report: Occupational bullous dermatosis: first report of skin lesions induced by PVC welding fume in a manufacturing worker172
Gene variants of glucocorticoid activation pathways and the outcomes of patients with Takayasu arteritis – a retrospective cohort study170
Knowledge, attitude, and practice of Chinese parents with infants (aged 0–3 years) toward immunity, gut microbiota and biotics: a comprehensive study170
Liver Ischemia and Reperfusion Induce Periportal Expression of Necroptosis Executor pMLKL Which Is Associated With Early Allograft Dysfunction After Transplantation166
Profiling of immune cell subsets and functional characteristics of cervical cancer based on single cell RNA sequencing166
Editorial: Immunity in aging and age-related diseases and dysfunctions163
Impacts of tacrolimus and glucocorticoids on peripheral blood T and B lymphocyte subsets in myasthenia gravis163
Impact of telitacicept on gonadal function in adult female patients with systemic lupus erythematosus: a prospective cohort study163
Misdiagnosis of Reactive Lymphadenopathy Remotely After COVID-19 Vaccination: A Case Report and Literature Review162
Alkaline sphingomyelinase (NPP7) impacts the homeostasis of intestinal T lymphocyte populations162
Editorial: Immunometabolism of T cells in skin infection, autoimmunity and cancer biology162
Neonatal overfeeding attenuates microgliosis and hippocampal damage in an infant rat model of pneumococcal meningitis161
The immunosuppressive mechanisms induced by sepsis and the corresponding treatment strategies158
Case Report: KLHL11 encephalitis in a female patient with dual primary malignancies of breast and lung cancer: response to FcRn inhibitor therapy158
The role of macrophages-mediated communications among cell compositions of tumor microenvironment in cancer progression156
Interferon therapy and its association with depressive disorders – A review156
Adenovirus Encoded Adjuvant (AdEnA) anti-CTLA-4, a novel strategy to improve Adenovirus based vaccines against infectious diseases and cancer155
Editorial: Community series in: the role of vitamin D as an immunomodulator, volume II155
IDO1-AhR axis increases T regulatory cells in Plasmodium vivax malaria infection154
Malaria and leishmaniasis: Updates on co-infection153
A potential strategy to rebuild the tumor immune microenvironment: PANoptosis151
Case report: A cyclic neutropenia patient with ELANE mutation accompanied by hemophagocytic lymphohistiocytosis151
Potential therapeutic effect of olfactory ensheathing cells in neurological diseases: neurodegenerative diseases and peripheral nerve injuries150
Capturing the multifaceted function of adipose tissue macrophages150
A large-scale database of T-cell receptor beta sequences and binding associations from natural and synthetic exposure to SARS-CoV-2149
Anoikis resistance of small airway epithelium is involved in the progression of chronic obstructive pulmonary disease147
Editorial: Novel biomarkers for predicting response to cancer immunotherapy145
Immuno-inflammatory-metabolic interactions in cardiovascular diseases: a review from basic mechanisms to clinical translation145
Serum C3 as an early-warning biomarker for renal pathological progression in DKD142
Overcoming immune resistance in hepatocellular carcinoma: insights into mechanisms, predictive factors, and interventional strategies141
C5a elevation in convalescents from severe COVID-19 is not associated with early complement activation markers C3bBbP or C4d141
Safety of JAK and IL-6 inhibitors in patients with rheumatoid arthritis: a multicenter cohort study141
Identification of key biomarkers related to fibrocartilage chondrocytes for osteoarthritis based on bulk, single-cell transcriptomic data141
Human B-1 cells are important contributors to the naturally-occurring IgM pool against the tumor-associated ganglioside Neu5GcGM3139
Longitudinal analysis of immunocyte responses and inflammatory cytokine profiles in SFTSV-infected rhesus macaques138
Lactobacillus spp. act in synergy to attenuate splenomegaly and lymphadenopathy in lupus-prone MRL/lpr mice137
Ferroptosis, necroptosis, and pyroptosis in the occurrence and development of ovarian cancer137
A transient receptor potential channel-related model based on machine learning for evaluating tumor microenvironment and immunotherapeutic strategies in acute myeloid leukemia136
Strategies of Targeting Inflammasome in the Treatment of Systemic Lupus Erythematosus136
Thrombomodulin and syndecan-1 and association with lung function in liver transplant recipients135
Chemokine ligand 2: beyond chemotaxis—a multifaceted role in tumor progression135
Editorial: p53 in cancer therapy: the impact of mutations on the genome guardian135
Branched-chain amino acid catabolism promotes M2 macrophage polarization134
The role of tumor-associated macrophages in HPV induced cervical cancer134
An intricate relationship between fibrosis and autoimmune diseases: a specific focus on unraveling its molecular, immunological, and epigenetic drivers133
Effects of tildrakizumab on circulating T cells in autoreactive psoriatic patients133
Serum Immunoglobulins, Pneumonia Risk, and Lung Function in Middle-Aged and Older Individuals: A Population-Based Cohort Study133
Immunotherapy for TKI-resistant, EGFR L858R-mutated non-small cell lung cancer: a systematic review and meta-analysis of randomized and single-arm studies133
Advancements in the investigation of gut microbiota-based strategies for stroke prevention and treatment131
Clinical characteristics, prognosis, and predictive modeling in class IV ± V lupus nephritis131
The impact of persistent organic pollutants on fertility: exposure to the environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin alters reproductive tract immune responses130
From bark to bench: innovations in QS-21 adjuvant characterization and manufacturing130
Identification of a growth-inhibitory epitope in PfRipr5, a malaria vaccine candidate against Plasmodium falciparum129
Entry into the lytic cycle exposes EBV-infected cells to NK cell killing via upregulation of the MICB ligand for NKG2D and activation of the CD56bright and NKG2A+KIR+CD56dim subsets129
Rapid screening and scaled manufacture of immunogenic virus-like particles in a tobacco BY-2 cell-free protein synthesis system129
The mARS complex: a critical mediator of immune regulation and homeostasis129
Network pharmacology to explore the novel anti-inflammatory mechanism of naringenin in intestinal ischemia/reperfusion injury129
NLRP1 Inflammasomes: A Potential Target for the Treatment of Several Types of Brain Injury128
Case report: Successful remission with upadacitinib in a young patient with anti-TNF-refractory intestinal Behçet’s disease128
Biofilm adaptation and mucosal immune dysregulation in recalcitrant chronic rhinosinusitis: from pathogenesis to a therapeutic roadmap128
The roles of AIM2 in neurodegenerative diseases: insights and therapeutic implications128
Optimizing monocyte-derived immune cell cultures: comparing xeno-free and xenogeneic conditions128
Causal associations between Helicobacter Pylori infection and the risk and symptoms of Parkinson’s disease: a Mendelian randomization study127
miR-107-enriched exosomes promote ROS/wnt/autophagy, inhibit intracellular mycobacterial growth and attenuate lung infection127
Comparative analysis of the neutralizing activity against SARS-CoV-2 Wuhan-Hu-1 strain and variants of concern: Performance evaluation of a pseudovirus-based neutralization assay127
A new personalized vaccine strategy based on inducing the pyroptosis of tumor cells in vivo by transgenic expression of a truncated GSDMD N-terminus127
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