OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Genetics is 49. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Compound heterozygous FAM20C gene variants in a patient with severe Raine syndrome: a case report	253
Editorial: Exploiting genetics and genomics to improve the understanding of eye diseases	206
A Nomogram for Predicting the Risk of Bone Metastasis in Newly Diagnosed Head and Neck Cancer Patients: A Real-World Data Retrospective Cohort Study From SEER Database	193
Editorial: Clinical Evaluation Criteria for Aging and Aging-Related Multimorbidity	159
Transcriptomic analysis of paired healthy human skeletal muscles to identify modulators of disease severity in DMD	138
EDNRA Gene rs1878406 Polymorphism is Associated With Susceptibility to Large Artery Atherosclerotic Stroke	120
Characterisation of the in-vivo miRNA landscape in Drosophila ribonuclease mutants reveals Pacman-mediated regulation of the highly conserved let-7 cluster during apoptotic processes	102
Editorial: Epigenetic mechanisms and epigenetic-based therapies in cardiometabolic and vascular disease	96
Identification of N7-methylguanosine-related IncRNA signature as a potential predictive biomarker for colon adenocarcinoma	93
Editorial: Epigenomics implication for economic traits in domestic animals	91
DNA methylation and mRNA expression of glutathione S-transferase alpha 4 are associated with intracranial aneurysms in a gender-dependent manner	90
Genetic Variation in the ZNF208 Gene at rs8103163 and rs7248488 Is Associated With Laryngeal Cancer in the Northwestern Chinese Han Male	90
Identifying Functions of Proteins in Mice With Functional Embedding Features	87
RET splice site variants in medullary thyroid carcinoma	85
Incorporating genome-wide and transcriptome-wide association studies to identify genetic elements of longissimus dorsi muscle in Huaxi cattle	83
SOCS3 is Related to Cell Proliferation in Neuronal Tissue: An Integrated Analysis of Bioinformatics and Experiments	83
Single nucleotide variants in nuclear pore complex disassembly pathway associated with poor survival in osteosarcoma	75
Transcriptome profiling and analysis of patients with esophageal squamous cell carcinoma from Kazakhstan	70
A Novel Age-Related Circular RNA Circ-ATXN2 Inhibits Proliferation, Promotes Cell Death and Adipogenesis in Rat Adipose Tissue-Derived Stromal Cells	69
Integrative analyses of prognosis, tumor immunity, and ceRNA network of the ferroptosis-associated gene FANCD2 in hepatocellular carcinoma	69
Selection Signature Analyses Revealed Genes Associated With Adaptation, Production, and Reproduction in Selected Goat Breeds in Kenya	68
Repression of enhancer RNA PHLDA1 promotes tumorigenesis and progression of Ewing sarcoma via decreasing infiltrating T‐lymphocytes: A bioinformatic analysis	68
Comparative Transcriptome Analysis Provides Insight into Spatio-Temporal Expression Characteristics and Genetic Regulatory Network in Postnatal Developing Subcutaneous and Visceral Fat of Bama Pig	67
Association of PTPN22 SNP1858 (rs2476601) and Gene SNP1123 (rs2488457) Polymorphism With Primary Immune Thrombocytopenia Susceptibility: A Meta-Analysis of Case-Control Studies and Trial Sequential An	66
High Expression of CEMIP Correlates Poor Prognosis and the Tumur Microenvironment in Breast Cancer as a Promisingly Prognostic Biomarker	65

Functional identification of two novel variants and a hypomorphic variant in ASS1 from patients with Citrullinemia type I	63
Editorial: Genetic and epigenetic aspects of non-coding RNAs in physiology and disease	62
Editorial: Cytogenomics: Structural Organization and Evolution of Genomes	60
Discovery of novel eGFR-associated multiple independent signals using a quasi-adaptive method	60
A novel signature to predict the neoadjuvant chemotherapy response of bladder carcinoma: Results from a territory multicenter real-world study	59
An Augmented High-Dimensional Graphical Lasso Method to Incorporate Prior Biological Knowledge for Global Network Learning	59
Case Report: Two Novel Frameshift Mutations in SLC20A2 and One Novel Splice Donor Mutation in PDGFB Associated With Primary Familial Brain Calcification	57
Case Report: A Novel Missense Variant in the SIPA1L3 Gene Associated With Cataracts in a Chinese Family	57
Editorial: Machine Learning and Mathematical Models for Single-Cell Data Analysis	56
Construction of a HOXA11-AS-Interacted Network in Keloid Fibroblasts Using Integrated Bioinformatic Analysis and in Vitro Validation	56
Editorial: Alternative Polyadenylation in Development and Disease	55
Editorial: Finding New Epigenomics and Epigenetics Biomarkers for Complex Diseases and Significant Developmental Events With Machine Learning Methods	55
Identification of a Gene Signature to Aid Treatment Decisions by Integrated Analysis of Mutated Genes Between Primary and Metastatic Prostate Cancer	54
LncRNA-mediated ceRNA network reveals the mechanism of action of Saorilao-4 decoction against pulmonary fibrosis	52
Machine learning potential predictor of idiopathic pulmonary fibrosis	52
Classical and machine learning tools for identifying yellow-seeded Brassica napus by fusion of hyperspectral features	51
Case Report: Novel ADA2 variants cause atypical adenosine deaminase 2 deficiency	51
Updates on the molecular spectrum of MEFV variants in lebanese patients with Familial Mediterranean Fever	51
The value of a metabolic and immune-related gene signature and adjuvant therapeutic response in pancreatic cancer	50
Editorial: Systems biology approaches to psychiatric and psychological disorders: unraveling the complexities	50
In silico design of an epitope-based vaccine ensemble for fasliolopsiasis	50
Case report: Discovery of novel CTNNB1 mutations and comparison of clinical characteristics in two patients with NEDSDV	50
Characterization of novel human endogenous retrovirus structures on chromosomes 6 and 7	49
Case Report: Identification of a Novel Heterozygous Missense Mutation in COL4A3 Gene Causing Variable Phenotypes in an Autosomal-Dominant Alport Syndrome Family	49
Retraction: Cytokinin and abiotic stress tolerance -what has been accomplished and the way forward?	49
Vitamin A family suppresses periodontitis by restoring mitochondrial metabolic reprogramming in macrophages through JAK-STAT pathway	49