OOIR: Observatory of International Research

Papers

(The H4-Index of Frontiers in Genetics is 51. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Regulatory role of N6-Methyladenosine on skeletal muscle development in Hu sheep	278
Editorial: Genetic and epigenetic aspects of non-coding RNAs in physiology and disease	222
Development of a risk model to predict prognosis in breast cancer based on cGAS-STING-related genes	173
Utilization of hypoxia-derived gene signatures to predict clinical outcomes and immune checkpoint blockade therapy responses in prostate cancer	149
Case report: Complete paternal isodisomy on chromosome 18 induces methylation changes in PARD6G-AS1 promotor in a case with arthrogryposis	120
Mitochondrial DNA heteroplasmy analysis in keratoconus patients from China	111
Editorial: The ethics and challenges of studying the genetics of marginalized populations	107
Editorial: Computational methods to analyze RNA data for human diseases	104
A syndrome differentiation model of TCM based on multi-label deep forest using biomedical text mining	97
Genetics and marker-assisted breeding for sex expression in cucumber	97
Identification of discriminant features from stationary pattern of nucleotide bases and their application to essential gene classification	95
Prediction of Alternative Drug-Induced Liver Injury Classifications Using Molecular Descriptors, Gene Expression Perturbation, and Toxicology Reports	95
Epigenome-wide DNA methylation profiling in comparison between pathological and physiological hypertrophy of human cardiomyocytes	92
Case Report: CNNM2 Mutations Cause Damaged Brain Development and Intractable Epilepsy in a Patient Without Hypomagnesemia	91
Development and validation of a TRP-related gene signature for overall survival prediction in lung adenocarcinoma	89
Editorial: Epigenetic mechanisms and epigenetic-based therapies in cardiometabolic and vascular disease	84
Loss-of-function variant in the LRR domain of SLITRK2 implicated in a neurodevelopmental disorder	79
Editorial: Genetics of reproduction for livestock species	77
Perthes Disease in a Child With Osteogenesis Imperfecta From a Rare Genetic Variant: A Case Report	77
Case Report: Prenatal Identification of a De Novo Mosaic Neocentric Marker Resulting in 13q31.1→qter Tetrasomy in a Mildly Affected Girl	72
Genome Size Estimation and Full-Length Transcriptome of Sphingonotus tsinlingensis: Genetic Background of a Drought-Adapted Grasshopper	70
Case Report: Prenatal Diagnosis of Postaxial Polydactyly With Bi-Allelic Variants in Smoothened (SMO)	70
Case Report: Whole-Exome Sequencing-Based Copy Number Variation Analysis Identified a Novel DRC1 Homozygous Exon Deletion in a Patient With Primary Ciliary Dyskinesia	69
Development and validation of a chromatin regulator prognostic signature in colon adenocarcinoma	68
Genetically predicted 1091 blood metabolites and 309 metabolite ratios in relation to risk of type 2 diabetes: a Mendelian randomization study	67

Footprints in the Sand: Deep Taxonomic Comparisons in Vertebrate Genomics to Unveil the Genetic Programs of Human Longevity	64
Diaphragmatic Hernia as a Prenatal Feature of Glycosylphosphatidylinositol Biosynthesis Defects and the Overlap With Fryns Syndrome – Literature Review	62
HNF1β, LHX1, and GGNBP2 deletion contributed to kidney and reproductive dysfunction in 17q12 deletion syndrome: evidence from a case report	62
MiRNA-Seq reveals key MicroRNAs involved in fat metabolism of sheep liver	61
The association of metabolic syndrome with telomere length as a marker of cellular aging: a systematic review and meta-analysis	59
Non-oral manifestations in adults with a clinical and molecularly confirmed diagnosis of periodontal Ehlers-Danlos syndrome	58
Editorial: New insights in cellular and molecular biology of cancer stem cells	58
Functional analysis of RRAS2 pathogenic variants with a Noonan-like phenotype	58
Subject clustering by IF-PCA and several recent methods	57
Mutational signatures representative transcriptomic perturbations in hepatocellular carcinoma	57
Hereditary orotic aciduria identified by newborn screening	57
Genetic tests as the strongest motivator of cooperation between participants and biobanks–Findings from cross-sectional study	55
iRGvalid: A Robust in silico Method for Optimal Reference Gene Validation	54
Bioinformatics revealed biomarkers for diagnosis in kidney stones	54
Transcriptional Regulation of Pine Male and Female Cone Initiation and Development: Key Players Identified Through Comparative Transcriptomics	54
Clinical characteristics and follow-up of complex arrhythmias associated with RYR2 gene mutations in children	53
Editorial: Genetic advancements for improving the plant tolerance to biotic and abiotic stresses	53
Construction of ceRNA network based on RNA-seq for identifying prognostic lncRNA biomarkers in Perthes disease	52
Refined expression quantitative trait locus analysis on adenocarcinoma at the gastroesophageal junction reveals susceptibility and prognostic markers	51
MFRP variations cause nanophthalmos in five Chinese families with distinct phenotypic diversity	51
Identification of Novel Compound Heterozygous Variants of the PNPLA6 Gene in Boucher–Neuhäuser Syndrome	51
Editorial: Gene Regulation Explored by Systems Biology in Livestock Science	51
Editorial: Recent advances in nutrigenomics: Making strides towards precision nutrition	51
COVID-19-specific transcriptomic signature detectable in blood across multiple cohorts	51
A combined transcriptomics and proteomics approach reveals S100A4 as a potential biomarker for Graves’ orbitopathy	51
Case Report: A Novel Gross Deletion in PAX3 (10.26 kb) Identified in a Chinese Family With Waardenburg Syndrome by Third-Generation Sequencing	51