Acta Pharmacologica Sinica

Article	Citations
Author Correction: Discovery of toxoflavin, a potent IRE1α inhibitor acting through structure-dependent oxidative inhibition	270
Single-dose methamphetamine administration impairs ORM retrieval in mice via excessive DA-mediated inhibition of PrLGlu activity	181
ADT-OH inhibits malignant melanoma metastasis in mice via suppressing CSE/CBS and FAK/Paxillin signaling pathway	153
Compound 38, a novel potent and selective antagonist of adenosine A2A receptor, enhances arousal in mice	137
Channelopathy of small- and intermediate-conductance Ca2+-activated K+ channels	114
Translin deletion impairs cocaine-induced locomotor sensitization and RGS8 expression in the nucleus accumbens	102
Otilonium bromide ameliorates pulmonary fibrosis in mice through activating phosphatase PPM1A	100
Cystathionine γ-lyase-derived H2S negatively regulates thymic egress via allosteric inhibition of sphingosine-1-phosphate lyase	97
GRK2-mediated phosphorylation and de-succinylation of PKM2 reduce macrophage glycolysis in rheumatoid arthritis	96
Reducing lipid peroxidation attenuates stress-induced susceptibility to herpes simplex virus type 1	94
Activating Wnt/β-catenin signaling by autophagic degradation of APC contributes to the osteoblast differentiation effect of soy isoflavone on osteoporotic mesenchymal stem cells	88
Ginsenoside Rg1 ameliorates stress-exacerbated Parkinson’s disease in mice by eliminating RTP801 and α-synuclein autophagic degradation obstacle	86
Satellite cell-derived exosome-mediated delivery of microRNA-23a/27a/26a cluster ameliorates the renal tubulointerstitial fibrosis in mouse diabetic nephropathy	86
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition	83
Natural product-based screening led to the discovery of a novel PXR agonist with anti-cholestasis activity	79
tRF3-IleAAT reduced extracellular matrix synthesis in diabetic kidney disease mice by targeting ZNF281 and inhibiting ferroptosis	78
S670, an amide derivative of 3-O-acetyl-11-keto-β-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome	76
Identification of Licoflavone C as a cap-dependent endonuclease inhibitor against severe fever with thrombocytopenia syndrome virus	73
Integration of machine learning and experimental validation reveals new lipid-lowering drug candidates	72
Targeted degradation of membrane and extracellular proteins with LYTACs	68
Paris saponin VII, a Hippo pathway activator, induces autophagy and exhibits therapeutic potential against human breast cancer cells	67
Iguratimod suppresses plasma cell differentiation and ameliorates experimental Sjögren’s syndrome in mice by promoting TEC kinase degradation	67
The hybrid oncolytic peptide NTP-385 potently inhibits adherent cancer cells by targeting the nucleus	62
Pyroptosis and pyroptosis-inducing cancer drugs	60
Aspirin triggers ferroptosis in hepatocellular carcinoma cells through restricting NF-κB p65-activated SLC7A11 transcription	58

Celastrol suppresses the growth of vestibular schwannoma in mice by promoting the degradation of β-catenin	58
MC1R and melanin-based molecular probes for theranostic of melanoma and beyond	58
Extracellular vesicles in vascular remodeling	56
Author Correction: ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway	55
Transcriptional regulation and small compound targeting of ACE2 in lung epithelial cells	55
Discovery and pharmacological characterization of 1,2,3,4-tetrahydroquinoline derivatives as RORγ inverse agonists against prostate cancer	54
Trametinib, an anti-tumor drug, promotes oligodendrocytes generation and myelin formation	54
Structure basis for inhibition of SARS-CoV-2 by the feline drug GC376	53
FX5, a non-steroidal glucocorticoid receptor antagonist, ameliorates diabetic cognitive impairment in mice	52
Flavokawain B alleviates LPS-induced acute lung injury via targeting myeloid differentiation factor 2	52
DNMT inhibition epigenetically restores the cGAS-STING pathway and activates RIG-I/MDA5-MAVS to enhance antitumor immunity	51
Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway	51
Liver X receptor inverse agonist SR9243 attenuates rheumatoid arthritis via modulating glycolytic metabolism of macrophages	51
143D, a novel selective KRASG12C inhibitor exhibits potent antitumor activity in preclinical models	50
Correction to: EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells	49
Transport mechanism and drug discovery of human monocarboxylate transporter 1	46
Insomnia-related rodent models in drug discovery	46
p52-ZER6: a determinant of tumor cell sensitivity to MDM2-p53 binding inhibitors	46
Dendritic cell-liposome conjugates reverse immunosuppressive tumor microenvironment for inhibiting colitis-associated colorectal cancer	45
Chronic infusion of ELABELA alleviates vascular remodeling in spontaneously hypertensive rats via anti-inflammatory, anti-oxidative and anti-proliferative effects	45
Gastrodin promotes CNS myelinogenesis and alleviates demyelinating injury by activating the PI3K/AKT/mTOR signaling	45
Dual-responsive nanoparticles loading bevacizumab and gefitinib for molecular targeted therapy against non-small cell lung cancer	43
Sortilin deletion in the prefrontal cortex and hippocampus ameliorates depressive-like behaviors in mice via regulating ASM/ceramide signaling	41
Antagonism of histamine H3 receptor promotes angiogenesis following focal cerebral ischemia	40
LN-439A, a novel BAP1 inhibitor, suppresses the growth of basal-like breast cancer by degrading KLF5	40
TRADD-mediated pyroptosis contributes to diabetic cardiomyopathy	39
Thoracic perivascular adipose tissue inhibits VSMC apoptosis and aortic aneurysm formation in mice via the secretome of browning adipocytes	39
Exploring the distinct activation mechanisms of neuromedin B receptor through multiple replica molecular dynamics simulations and Markov state modeling	38
Author Correction: Anti-diabetic drug canagliflozin hinders skeletal muscle regeneration in mice	38
Mitochondrial calcium uniporter promotes kidney aging in mice through inducing mitochondrial calcium-mediated renal tubular cell senescence	38
Correction: Chemokine CCL2 promotes cardiac regeneration and repair in myocardial infarction mice via activation of the JNK/STAT3 axis	37
Chemistry and bioactivity of secondary metabolites from South China Sea marine fauna and flora: recent research advances and perspective	37
Selective EZH2 inhibitor zld1039 alleviates inflammation in cisplatin-induced acute kidney injury partially by enhancing RKIP and suppressing NF-κB p65 pathway	36
Contrastive learning-based drug screening model for GluN1/GluN3A inhibitors	36
Cytosolic DNA initiates a vicious circle of aging-related endothelial inflammation and mitochondrial dysfunction via STING: the inhibitory effect of Cilostazol	35
A high-throughput screening campaign against PFKFB3 identified potential inhibitors with novel scaffolds	35
Preclinical characterization of [18F]D2-LW223: an improved metabolically stable PET tracer for imaging the translocator protein 18 kDa (TSPO) in neuroinflammatory rodent models and non-human primates	35
Discovery of novel DprE1 inhibitors via computational bioactivity fingerprints and structure-based virtual screening	35
14-3-3ζ inhibits maladaptive repair in renal tubules by regulating YAP and reduces renal interstitial fibrosis	35
Selumetinib promotes coronary collateral circulation by inducing M2-like macrophage polarization following myocardial infarction	34
Antiatherosclerotic effect of dehydrocorydaline on ApoE−/− mice: inhibition of macrophage inflammation	34
SAAINT-DB: a comprehensive structural antibody database for antibody modeling and design	34
Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats	34
Oridonin ameliorates caspase-9-mediated brain neuronal apoptosis in mouse with ischemic stroke by inhibiting RIPK3-mediated mitophagy	33
Fangchinoline-mediated autophagy inhibition amplifies antigen presentation and PD-1 blockade efficacy in lung cancer	33
RIPK1 inhibition contributes to lysosomal membrane stabilization in ischemic astrocytes via a lysosomal Hsp70.1B-dependent mechanism	33
Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis	32
NASH: regulatory considerations for clinical drug development and U.S. FDA approval	32
JOSD2 alleviates acute kidney injury through deubiquitinating SIRT7 and negativity regulating SIRT7-NF-κB inflammatory pathway in renal tubular epithelial cells	32
The diverse role of the raphe 5-HTergic systems in epilepsy	32

Deletion of p38γ attenuates ethanol consumption- and acetaminophen-induced liver injury in mice through promoting Dlg1	32
AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors	32
Celastrol attenuates hepatitis C virus translation and inflammatory response in mice by suppressing heat shock protein 90β	31
Advances in cannabinoid receptors pharmacology: from receptor structural insights to ligand discovery	31
Regulation of toll-like receptor (TLR) signaling pathways in atherosclerosis: from mechanisms to targeted therapeutics	31
SGLT2 inhibitor empagliflozin promotes revascularization in diabetic mouse hindlimb ischemia by inhibiting ferroptosis	31
Methionine-choline deficient diet deteriorates DSS-induced murine colitis through disturbance of gut microbes and infiltration of macrophages	31
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling	31
ROCK1 inhibition improves wound healing in diabetes via RIPK4/AMPK pathway	30
Esculetin facilitates post-stroke rehabilitation by inhibiting CKLF1-mediated neutrophil infiltration	30
Melatonin ameliorates bleomycin-induced pulmonary fibrosis via activating NRF2 and inhibiting galectin-3 expression	30
CP-25 enhances OAT1-mediated absorption of methotrexate in synoviocytes of collagen-induced arthritis rats	29
Therapeutic potential and pharmacological mechanisms of Traditional Chinese Medicine in gout treatment	29
Circular RNA circDhx32 promotes cardiac inflammatory responses in mouse cardiac ischemia-reperfusion injury via binding to FOXO1 competed with AdipoR1	28
Current status and challenges in the drug treatment for fibrotic nonalcoholic steatohepatitis	28
Dezocine as a potent analgesic: overview of its pharmacological characterization	28
Skullcapflavone II, a novel NQO1 inhibitor, alleviates aristolochic acid I-induced liver and kidney injury in mice	28
Co-inhibition of RAGE and TLR4 sensitizes pancreatic cancer to irreversible electroporation in mice by disrupting autophagy	27
Molecular recognition of two approved drugs Macimorelin and Anamorelin by the growth hormone secretagogue receptor	27
Scutellarin suppresses triple-negative breast cancer metastasis by inhibiting TNFα-induced vascular endothelial barrier breakdown	27
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2	26
Proteomic characterization of post-translational modifications in drug discovery	26
Z16b, a natural compound from Ganoderma cochlear is a novel RyR2 stabilizer preventing catecholaminergic polymorphic ventricular tachycardia	26
Endothelial dysfunction: mechanisms and contribution to diseases	26
Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function	26
Discovery of a selective TRF2 inhibitor FKB04 induced telomere shortening and senescence in liver cancer cells	26
NADPH acts as an endogenous P2X7 receptor modulator to gate neuroinflammatory responses of microglia	26
Wogonin attenuates septic cardiomyopathy by suppressing ALOX15-mediated ferroptosis	26
Phenethyl isothiocyanate inhibits metastasis potential of non-small cell lung cancer cells through FTO mediated TLE1 m6A modification	26
Dorsal raphe GABA-ergic neurons regulate the susceptibility to social transfer of pain in mice	25
Adaptor protein Src-homology 2 domain containing E (SH2E) deficiency induces heart defect in zebrafish	25
Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis	25
Author Correction: Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis	25
c-FLIP promotes drug resistance in non-small-cell lung cancer cells via upregulating FoxM1 expression	25
Discovery of a nitroaromatic nannocystin with potent in vivo anticancer activity against colorectal cancer by targeting AKT1	25
Development of PI3Kγ selective inhibitors: the strategies and application	25
Endothelial deubiquinatase YOD1 mediates Ang II-induced vascular endothelial-mesenchymal transition and remodeling by regulating β-catenin	24
Novel treatment for refractory rheumatoid arthritis with total glucosides of paeony and nobiletin codelivered in a self-nanoemulsifying drug delivery system	24
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease	24
Celastrol inhibits the DPYSL2-JAK/STAT pathway by targeting mito-IDHs mediated mitochondrial metabolism to exhaust breast cancer	24
IFN-α inhibits HBV transcription and replication by promoting HDAC3-mediated de-2-hydroxyisobutyrylation of histone H4K8 on HBV cccDNA minichromosome in liver	24
Peptidoglycan isolated from the fruit of Lycium barbarum alleviates liver fibrosis in mice by regulating the TGF-β/Smad7 signaling and gut microbiota	24
PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours	24
Cardiovascular adverse effects of antiviral therapies for COVID-19: Evidence and plausible mechanisms	24
Aspirin modulates succinylation of PGAM1K99 to restrict the glycolysis through NF-κB/HAT1/PGAM1 signaling in liver cancer	24
Targeting PI3Kα overcomes resistance to KRasG12C inhibitors mediated by activation of EGFR and/or IGF1R	24
Development of orthotopic mouse models for mid-low rectal cancer	23
The role of microglia in neurodegenerative diseases: from the perspective of ferroptosis	23
Anti-diabetic drug canagliflozin hinders skeletal muscle regeneration in mice	23
Thioridazine protects against disturbed flow-induced atherosclerosis by inhibiting RhoA/YAP-mediated endothelial inflammation	23
Electrophysiological characterization of human KCNT1 channel modulators and the therapeutic potential of hydroquinine and tipepidine in KCNT1 mutation-associated epilepsy mouse model	23
Correction: Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway	23
(+)-Borneol enantiomer ameliorates epileptic seizure via decreasing the excitability of glutamatergic transmission	22
zDHHC20-driven S-palmitoylation of CD80 is required for its costimulatory function	22
NFAT inhibitor 11R-VIVIT ameliorates mouse renal fibrosis after ischemia-reperfusion-induced acute kidney injury	22
Mitochondrial-derived damage-associated molecular patterns amplify neuroinflammation in neurodegenerative diseases	22
Serum amyloid A3 aggravates bleomycin-induced pulmonary fibrosis through Krüppel-like factor 6-dependent interlukin-36α expression	22
G-protein coupled receptor kinase 2 mediates rheumatoid arthritis-induced depression-like behaviors via the hippocampal CRHR1 signaling pathway	22
Asiatic acid ameliorates doxorubicin-induced cardiotoxicity by promoting FPN-mediated iron export and inhibiting ferroptosis	22
GFPBW1, a β-glucan from Grifola frondosa as vaccine adjuvant: APCs activation and maturation	22
Dehydrocorydaline maintains the vascular smooth muscle cell contractile phenotype by upregulating Spta1	22
Revisiting the role of GDF15 in atherosclerosis in mouse and human	22
Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity	22
Author Correction: Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid β production and clearance	22
Poria cocos: traditional uses, triterpenoid components and their renoprotective pharmacology	22
DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3K-Akt-NF-κB pathway	21
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model	21
Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis	21
Cyclic GMP-AMP synthase recognizes the physical features of DNA	21
Chronic β-adrenergic stress contributes to cardiomyopathy in rodents with collagen-induced arthritis	21
Prenatal dexamethasone exposure impairs rat blood-testis barrier function and sperm quality in adult offspring via GR/KDM1B/FSTL3/TGFβ signaling	21
Targeting cholesterol metabolism: a promising therapy strategy for cancer	21
GPR41 deficiency aggravates type 1 diabetes in streptozotocin-treated mice by promoting dendritic cell maturation	21
Hypocrellin A from an ethnic medicinal fungus protects against NLRP3-driven gout in mice by suppressing inflammasome activation	21
Gentiopicroside ameliorates psoriasis-like skin lesions in mice via regulating the Keap1-Nrf2 pathway and inhibiting keratinocyte activation	20
Targeting cyclin-dependent kinase 9 in cancer therapy	20
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway	20
Luteolin ameliorates chronic stress-induced depressive-like behaviors in mice by promoting the Arginase-1+ microglial phenotype via a PPARγ-dependent mechanism	20
Inhibiting the Otub1/phosphorylated STAT3 axis for the treatment of non-small cell lung cancer	20
Betaine-homocysteine methyltransferase protects against acetaminophen-induced acute liver failure via BACH1-SCD1-oleic acid axis	20

Pharmacological inhibition of FABP7 by MF 6 counteracts cerebellum dysfunction in an experimental multiple system atrophy mouse model	20
Urolithin A ameliorates obesity-induced metabolic cardiomyopathy in mice via mitophagy activation	20
Chalcone derivatives ameliorate lipopolysaccharide-induced acute lung injury and inflammation by targeting MD2	20
AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage	20
Novel insights into NOD-like receptors in renal diseases	20
Targeted VEGFA therapy in regulating early acute kidney injury and late fibrosis	20
GLP-1 mimetics as a potential therapy for nonalcoholic steatohepatitis	19
SARS-CoV-2 receptor binding domain radio-probe: a non-invasive approach for angiotensin-converting enzyme 2 mapping in mice	19
Circular RNA hsa_circ_0000288 protects against epilepsy in mice by binding to and stabilizing caprin1 protein	19
Activation of D2-like dopamine receptors improves the neuronal network and cognitive function of PPT1KI mice	19
Somatostatin receptor 2 targeting peptide modifications for peptide-drug conjugate treatment of small cell lung cancer	19
Multifaceted roles of UFMylation in health and disease	19
Adiponectin receptor agonist AdipoRon modulates human and mouse platelet function	19
Krüppel-like factors: potential roles in blood-brain barrier dysfunction and epileptogenesis	19
NADPHnet: a novel strategy to predict compounds for regulation of NADPH metabolism via network-based methods	19
Modeling exposure-driven adverse events of EGFR TKIs in the treatment of patients with non-small cell lung cancer	19
Neuropeptide-mediated activation of astrocytes improves stress resilience in mice by modulating cortical neural synapses	19
Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma	19
Exploring the constitutive activation mechanism of the class A orphan GPR20	19
Correction: A novel annexin dimer targets microglial phagocytosis of astrocytes to protect the brain-blood barrier after cerebral ischemia	19
Characterization of LTr1 derived from cruciferous vegetables as a novel anti-glioma agent via inhibiting TrkA/PI3K/AKT pathway	19
Inhibition of HIF-prolyl hydroxylase promotes renal tubule regeneration via the reprogramming of renal proximal tubular cells	19
Inhibition of Setd7 protects against cardiomyocyte hypertrophy via inhibiting lipid oxidation	18
Brigatinib, a newly discovered AXL inhibitor, suppresses AXL-mediated acquired resistance to osimertinib in EGFR-mutated non-small cell lung cancer	18
Discovery of FO-4-15, a novel 1,2,4-oxadiazole derivative, ameliorates cognitive impairments in 3×Tg mice by activating the mGluR1/CaMKIIα pathway	18
ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway	18
Inhibition of CD36 ameliorates mouse spinal cord injury by accelerating microglial lipophagy	18
The PIWI-interacting RNA CRAPIR alleviates myocardial ischemia‒reperfusion injury by reducing p53-mediated apoptosis via binding to SRSF1	18
Updates on novel pharmacotherapeutics for the treatment of nonalcoholic steatohepatitis	18
Notoginsenoside R1 protects against myocardial ischemia/reperfusion injury in mice via suppressing TAK1-JNK/p38 signaling	18
Prenatal dexamethasone exposure programs the decreased testosterone synthesis in offspring rats by low level of endogenous glucocorticoids	18
Dysregulation of iron homeostasis and methamphetamine reward behaviors in Clk1-deficient mice	18
PHLDA1 contributes to hypoxic ischemic brain injury in neonatal rats via inhibiting FUNDC1-mediated mitophagy	18
Dl-3-n-butylphthalide promotes angiogenesis in ischemic stroke mice through upregulating autocrine and paracrine sonic hedgehog	18
Cardiac-specific deletion of BRG1 ameliorates ventricular arrhythmia in mice with myocardial infarction	18
Colchicine reduces neointima formation and VSMC phenotype transition by modulating SRF-MYOCD activation and autophagy	17
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho	17
Inhibiting the transcription and replication of Ebola viruses by disrupting the nucleoprotein and VP30 protein interaction with small molecules	17
MMP-9 inhibitor SB-3CT improves neurological outcomes in ischemic stroke mice by modulation of astrocytic lipid metabolism	17
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor	17
A novel selective ERK1/2 inhibitor, Laxiflorin B, targets EGFR mutation subtypes in non-small-cell lung cancer	17
Indoxyl sulphate-TNFα axis mediates uremic encephalopathy in rodent acute kidney injury	17
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice	17
Tetramethylpyrazine prevents liver fibrotic injury in mice by targeting hepatocyte-derived and mitochondrial DNA-enriched extracellular vesicles	17
Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson’s disease models	17
Thermoregulatory pathway underlying the pyrogenic effects of prostaglandin E2 in the lateral parabrachial nucleus of male rats	17
Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method	17
Novel Caspase-1 inhibitor CZL80 improves neurological function in mice after progressive ischemic stroke within a long therapeutic time-window	17
Pharmacological characterization of the small molecule 03A10 as an inhibitor of α-synuclein aggregation for Parkinson’s disease treatment	17
Heat shock protein family A member 8 serving as a co-activator of transcriptional factor ETV4 up-regulates PHLDA2 to promote the growth of liver cancer	17
Chemokine CCL2 promotes cardiac regeneration and repair in myocardial infarction mice via activation of the JNK/STAT3 axis	17
124I-labeled anti-CD147 antibody for noninvasive detection of CD147-positive pan-cancers: construction and preclinical studies	17
Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction	17
A novel small-molecule PCSK9 inhibitor E28362 ameliorates hyperlipidemia and atherosclerosis	16
Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II	16
AI-enhanced virtual screening approach to hit identification for GluN1/GluN3A NMDA receptor	16
Disturbance of suprachiasmatic nucleus function improves cardiac repair after myocardial infarction by IGF2-mediated macrophage transition	16
α-MSH-catabolic enzyme prolylcarboxypeptidase in nucleus accumbens shell ameliorates stress susceptibility in mice through regulating synaptic plasticity	16
The aminosteroid U73122 promotes oligodendrocytes generation and myelin formation	16
Role of thrombospondin-1 in high-salt–induced mesenteric artery endothelial impairment in rats	16
Decoding ligand recognition and constitutive activation of histamine H3 and H4 receptors	16
Serum granulosa cell-derived TNF-α promotes inflammation and apoptosis of renal tubular cells and PCOS-related kidney injury through NF-κB signaling	16
Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function	16
Author Correction: α-Galactosylceramide and its analog OCH differentially affect the pathogenesis of ISO-induced cardiac injury in mice	16
USP11 promotes renal tubular cell pyroptosis and fibrosis in UUO mice via inhibiting KLF4 ubiquitin degradation	16
Differential modulation of subthalamic projection neurons by short-term and long-term electrical stimulation in physiological and parkinsonian conditions	16
6-Methyl flavone inhibits Nogo-B expression and improves high fructose diet-induced liver injury in mice	16
YY1/HIF-1α/mROS positive-feedback loop exacerbates glomerular mesangial cell proliferation in mouse early diabetic kidney disease	16
Liver receptor homolog-1: structures, related diseases, and drug discovery	16