Acta Pharmacologica Sinica

Article	Citations
Author Correction: Discovery of toxoflavin, a potent IRE1α inhibitor acting through structure-dependent oxidative inhibition	266
Celastrol suppresses the growth of vestibular schwannoma in mice by promoting the degradation of β-catenin	164
Single-dose methamphetamine administration impairs ORM retrieval in mice via excessive DA-mediated inhibition of PrLGlu activity	151
Otilonium bromide ameliorates pulmonary fibrosis in mice through activating phosphatase PPM1A	128
Channelopathy of small- and intermediate-conductance Ca2+-activated K+ channels	101
Iguratimod suppresses plasma cell differentiation and ameliorates experimental Sjögren’s syndrome in mice by promoting TEC kinase degradation	98
Ginsenoside Rg1 ameliorates stress-exacerbated Parkinson’s disease in mice by eliminating RTP801 and α-synuclein autophagic degradation obstacle	97
Translin deletion impairs cocaine-induced locomotor sensitization and RGS8 expression in the nucleus accumbens	94
S670, an amide derivative of 3-O-acetyl-11-keto-β-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome	93
Identification of Licoflavone C as a cap-dependent endonuclease inhibitor against severe fever with thrombocytopenia syndrome virus	89
Compound 38, a novel potent and selective antagonist of adenosine A2A receptor, enhances arousal in mice	88
Integration of machine learning and experimental validation reveals new lipid-lowering drug candidates	85
Cystathionine γ-lyase-derived H2S negatively regulates thymic egress via allosteric inhibition of sphingosine-1-phosphate lyase	81
ADT-OH inhibits malignant melanoma metastasis in mice via suppressing CSE/CBS and FAK/Paxillin signaling pathway	81
Natural product-based screening led to the discovery of a novel PXR agonist with anti-cholestasis activity	79
Aspirin triggers ferroptosis in hepatocellular carcinoma cells through restricting NF-κB p65-activated SLC7A11 transcription	73
Extracellular vesicles in vascular remodeling	73
GRK2-mediated phosphorylation and de-succinylation of PKM2 reduce macrophage glycolysis in rheumatoid arthritis	73
Reducing lipid peroxidation attenuates stress-induced susceptibility to herpes simplex virus type 1	67
The hybrid oncolytic peptide NTP-385 potently inhibits adherent cancer cells by targeting the nucleus	66
MC1R and melanin-based molecular probes for theranostic of melanoma and beyond	65
Paris saponin VII, a Hippo pathway activator, induces autophagy and exhibits therapeutic potential against human breast cancer cells	63
Targeted degradation of membrane and extracellular proteins with LYTACs	62
Satellite cell-derived exosome-mediated delivery of microRNA-23a/27a/26a cluster ameliorates the renal tubulointerstitial fibrosis in mouse diabetic nephropathy	59
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition	59

Pyroptosis and pyroptosis-inducing cancer drugs	58
Activating Wnt/β-catenin signaling by autophagic degradation of APC contributes to the osteoblast differentiation effect of soy isoflavone on osteoporotic mesenchymal stem cells	57
tRF3-IleAAT reduced extracellular matrix synthesis in diabetic kidney disease mice by targeting ZNF281 and inhibiting ferroptosis	56
Transport mechanism and drug discovery of human monocarboxylate transporter 1	54
Transcriptional regulation and small compound targeting of ACE2 in lung epithelial cells	54
143D, a novel selective KRASG12C inhibitor exhibits potent antitumor activity in preclinical models	53
Thoracic perivascular adipose tissue inhibits VSMC apoptosis and aortic aneurysm formation in mice via the secretome of browning adipocytes	53
Author Correction: ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway	53
Structure basis for inhibition of SARS-CoV-2 by the feline drug GC376	53
Discovery and pharmacological characterization of 1,2,3,4-tetrahydroquinoline derivatives as RORγ inverse agonists against prostate cancer	52
Trametinib, an anti-tumor drug, promotes oligodendrocytes generation and myelin formation	52
Mitochondrial calcium uniporter promotes kidney aging in mice through inducing mitochondrial calcium-mediated renal tubular cell senescence	51
Flavokawain B alleviates LPS-induced acute lung injury via targeting myeloid differentiation factor 2	51
Correction to: EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells	50
Gastrodin promotes CNS myelinogenesis and alleviates demyelinating injury by activating the PI3K/AKT/mTOR signaling	49
FX5, a non-steroidal glucocorticoid receptor antagonist, ameliorates diabetic cognitive impairment in mice	49
Exploring the distinct activation mechanisms of neuromedin B receptor through multiple replica molecular dynamics simulations and Markov state modeling	48
Dual-responsive nanoparticles loading bevacizumab and gefitinib for molecular targeted therapy against non-small cell lung cancer	48
Sortilin deletion in the prefrontal cortex and hippocampus ameliorates depressive-like behaviors in mice via regulating ASM/ceramide signaling	47
LN-439A, a novel BAP1 inhibitor, suppresses the growth of basal-like breast cancer by degrading KLF5	47
Antagonism of histamine H3 receptor promotes angiogenesis following focal cerebral ischemia	45
Liver X receptor inverse agonist SR9243 attenuates rheumatoid arthritis via modulating glycolytic metabolism of macrophages	44
Chronic infusion of ELABELA alleviates vascular remodeling in spontaneously hypertensive rats via anti-inflammatory, anti-oxidative and anti-proliferative effects	43
TRADD-mediated pyroptosis contributes to diabetic cardiomyopathy	43
Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle	42
Identification of pimavanserin tartrate as a potent Ca2+-calcineurin-NFAT pathway inhibitor for glioblastoma therapy	42
Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway	42
p52-ZER6: a determinant of tumor cell sensitivity to MDM2-p53 binding inhibitors	42
Insomnia-related rodent models in drug discovery	41
Author Correction: Anti-diabetic drug canagliflozin hinders skeletal muscle regeneration in mice	40
Chemistry and bioactivity of secondary metabolites from South China Sea marine fauna and flora: recent research advances and perspective	39
Contrastive learning-based drug screening model for GluN1/GluN3A inhibitors	39
The diverse role of the raphe 5-HTergic systems in epilepsy	38
JOSD2 alleviates acute kidney injury through deubiquitinating SIRT7 and negativity regulating SIRT7-NF-κB inflammatory pathway in renal tubular epithelial cells	38
Discovery of novel MIF inhibitors that attenuate microglial inflammatory activation by structures-based virtual screening and in vitro bioassays	37
Fangchinoline-mediated autophagy inhibition amplifies antigen presentation and PD-1 blockade efficacy in lung cancer	36
14-3-3ζ inhibits maladaptive repair in renal tubules by regulating YAP and reduces renal interstitial fibrosis	35
Correction: Chemokine CCL2 promotes cardiac regeneration and repair in myocardial infarction mice via activation of the JNK/STAT3 axis	35
Preclinical characterization of [18F]D2-LW223: an improved metabolically stable PET tracer for imaging the translocator protein 18 kDa (TSPO) in neuroinflammatory rodent models and non-human primates	35
Deletion of p38γ attenuates ethanol consumption- and acetaminophen-induced liver injury in mice through promoting Dlg1	35
Discovery of novel DprE1 inhibitors via computational bioactivity fingerprints and structure-based virtual screening	34
Cytosolic DNA initiates a vicious circle of aging-related endothelial inflammation and mitochondrial dysfunction via STING: the inhibitory effect of Cilostazol	34
Methionine-choline deficient diet deteriorates DSS-induced murine colitis through disturbance of gut microbes and infiltration of macrophages	34
SAAINT-DB: a comprehensive structural antibody database for antibody modeling and design	34
Selumetinib promotes coronary collateral circulation by inducing M2-like macrophage polarization following myocardial infarction	34
Celastrol attenuates hepatitis C virus translation and inflammatory response in mice by suppressing heat shock protein 90β	33
Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats	33
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling	33
Melatonin ameliorates bleomycin-induced pulmonary fibrosis via activating NRF2 and inhibiting galectin-3 expression	32
Antiatherosclerotic effect of dehydrocorydaline on ApoE−/− mice: inhibition of macrophage inflammation	32

Regulation of toll-like receptor (TLR) signaling pathways in atherosclerosis: from mechanisms to targeted therapeutics	32
Advances in cannabinoid receptors pharmacology: from receptor structural insights to ligand discovery	32
A high-throughput screening campaign against PFKFB3 identified potential inhibitors with novel scaffolds	31
SGLT2 inhibitor empagliflozin promotes revascularization in diabetic mouse hindlimb ischemia by inhibiting ferroptosis	31
Selective EZH2 inhibitor zld1039 alleviates inflammation in cisplatin-induced acute kidney injury partially by enhancing RKIP and suppressing NF-κB p65 pathway	31
AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors	31
RIPK1 inhibition contributes to lysosomal membrane stabilization in ischemic astrocytes via a lysosomal Hsp70.1B-dependent mechanism	30
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein	30
NASH: regulatory considerations for clinical drug development and U.S. FDA approval	30
Oridonin ameliorates caspase-9-mediated brain neuronal apoptosis in mouse with ischemic stroke by inhibiting RIPK3-mediated mitophagy	30
Therapeutic potential and pharmacological mechanisms of Traditional Chinese Medicine in gout treatment	30
Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis	30
Esculetin facilitates post-stroke rehabilitation by inhibiting CKLF1-mediated neutrophil infiltration	30
Wogonin attenuates septic cardiomyopathy by suppressing ALOX15-mediated ferroptosis	29
Discovery of a selective TRF2 inhibitor FKB04 induced telomere shortening and senescence in liver cancer cells	29
Co-inhibition of RAGE and TLR4 sensitizes pancreatic cancer to irreversible electroporation in mice by disrupting autophagy	28
Circular RNA circDhx32 promotes cardiac inflammatory responses in mouse cardiac ischemia-reperfusion injury via binding to FOXO1 competed with AdipoR1	28
Z16b, a natural compound from Ganoderma cochlear is a novel RyR2 stabilizer preventing catecholaminergic polymorphic ventricular tachycardia	28
ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome	28
Current status and challenges in the drug treatment for fibrotic nonalcoholic steatohepatitis	28
CP-25 enhances OAT1-mediated absorption of methotrexate in synoviocytes of collagen-induced arthritis rats	28
ROCK1 inhibition improves wound healing in diabetes via RIPK4/AMPK pathway	28
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2	28
Scutellarin suppresses triple-negative breast cancer metastasis by inhibiting TNFα-induced vascular endothelial barrier breakdown	27
Endothelial dysfunction: mechanisms and contribution to diseases	27
Molecular recognition of two approved drugs Macimorelin and Anamorelin by the growth hormone secretagogue receptor	27
Phenethyl isothiocyanate inhibits metastasis potential of non-small cell lung cancer cells through FTO mediated TLE1 m6A modification	27
Dezocine as a potent analgesic: overview of its pharmacological characterization	26
Development of PI3Kγ selective inhibitors: the strategies and application	26
Proteomic characterization of post-translational modifications in drug discovery	26
Skullcapflavone II, a novel NQO1 inhibitor, alleviates aristolochic acid I-induced liver and kidney injury in mice	26
Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function	26
Adaptor protein Src-homology 2 domain containing E (SH2E) deficiency induces heart defect in zebrafish	26
Anti-diabetic drug canagliflozin hinders skeletal muscle regeneration in mice	25
c-FLIP promotes drug resistance in non-small-cell lung cancer cells via upregulating FoxM1 expression	25
Author Correction: Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis	25
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease	25
Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis	24
Dorsal raphe GABA-ergic neurons regulate the susceptibility to social transfer of pain in mice	24
zDHHC20-driven S-palmitoylation of CD80 is required for its costimulatory function	24
Cardiovascular adverse effects of antiviral therapies for COVID-19: Evidence and plausible mechanisms	24
Asiatic acid ameliorates doxorubicin-induced cardiotoxicity by promoting FPN-mediated iron export and inhibiting ferroptosis	24
GFPBW1, a β-glucan from Grifola frondosa as vaccine adjuvant: APCs activation and maturation	24
Electrophysiological characterization of human KCNT1 channel modulators and the therapeutic potential of hydroquinine and tipepidine in KCNT1 mutation-associated epilepsy mouse model	24
Endothelial deubiquinatase YOD1 mediates Ang II-induced vascular endothelial-mesenchymal transition and remodeling by regulating β-catenin	24
Novel treatment for refractory rheumatoid arthritis with total glucosides of paeony and nobiletin codelivered in a self-nanoemulsifying drug delivery system	24
Peptidoglycan isolated from the fruit of Lycium barbarum alleviates liver fibrosis in mice by regulating the TGF-β/Smad7 signaling and gut microbiota	24
Development of orthotopic mouse models for mid-low rectal cancer	23
IFN-α inhibits HBV transcription and replication by promoting HDAC3-mediated de-2-hydroxyisobutyrylation of histone H4K8 on HBV cccDNA minichromosome in liver	23
G-protein coupled receptor kinase 2 mediates rheumatoid arthritis-induced depression-like behaviors via the hippocampal CRHR1 signaling pathway	23
The role of microglia in neurodegenerative diseases: from the perspective of ferroptosis	23
Celastrol inhibits the DPYSL2-JAK/STAT pathway by targeting mito-IDHs mediated mitochondrial metabolism to exhaust breast cancer	23
Correction: Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway	23
Dehydrocorydaline maintains the vascular smooth muscle cell contractile phenotype by upregulating Spta1	22
Discovery of a nitroaromatic nannocystin with potent in vivo anticancer activity against colorectal cancer by targeting AKT1	22
NFAT inhibitor 11R-VIVIT ameliorates mouse renal fibrosis after ischemia-reperfusion-induced acute kidney injury	22
Serum amyloid A3 aggravates bleomycin-induced pulmonary fibrosis through Krüppel-like factor 6-dependent interlukin-36α expression	22
Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity	22
Mitochondrial-derived damage-associated molecular patterns amplify neuroinflammation in neurodegenerative diseases	22
Revisiting the role of GDF15 in atherosclerosis in mouse and human	22
(+)-Borneol enantiomer ameliorates epileptic seizure via decreasing the excitability of glutamatergic transmission	22
Aspirin modulates succinylation of PGAM1K99 to restrict the glycolysis through NF-κB/HAT1/PGAM1 signaling in liver cancer	22
PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours	22
Prenatal dexamethasone exposure impairs rat blood-testis barrier function and sperm quality in adult offspring via GR/KDM1B/FSTL3/TGFβ signaling	21
Cyclic GMP-AMP synthase recognizes the physical features of DNA	21
Novel insights into NOD-like receptors in renal diseases	21
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model	21
GPR41 deficiency aggravates type 1 diabetes in streptozotocin-treated mice by promoting dendritic cell maturation	21
Inhibiting the Otub1/phosphorylated STAT3 axis for the treatment of non-small cell lung cancer	21
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway	21
Targeting cholesterol metabolism: a promising therapy strategy for cancer	21
Thioridazine protects against disturbed flow-induced atherosclerosis by inhibiting RhoA/YAP-mediated endothelial inflammation	21
Targeting PI3Kα overcomes resistance to KRasG12C inhibitors mediated by activation of EGFR and/or IGF1R	21
Luteolin ameliorates chronic stress-induced depressive-like behaviors in mice by promoting the Arginase-1+ microglial phenotype via a PPARγ-dependent mechanism	21
Chronic β-adrenergic stress contributes to cardiomyopathy in rodents with collagen-induced arthritis	21
Targeting cyclin-dependent kinase 9 in cancer therapy	21
Author Correction: Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid β production and clearance	21
Poria cocos: traditional uses, triterpenoid components and their renoprotective pharmacology	21
Hypocrellin A from an ethnic medicinal fungus protects against NLRP3-driven gout in mice by suppressing inflammasome activation	21
Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis	21

Pharmacological inhibition of FABP7 by MF 6 counteracts cerebellum dysfunction in an experimental multiple system atrophy mouse model	21
Gentiopicroside ameliorates psoriasis-like skin lesions in mice via regulating the Keap1-Nrf2 pathway and inhibiting keratinocyte activation	21
Urolithin A ameliorates obesity-induced metabolic cardiomyopathy in mice via mitophagy activation	20
DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3K-Akt-NF-κB pathway	20
Chalcone derivatives ameliorate lipopolysaccharide-induced acute lung injury and inflammation by targeting MD2	20
Cardiac-specific deletion of BRG1 ameliorates ventricular arrhythmia in mice with myocardial infarction	20
Tetrandrine alleviates silicosis by inhibiting canonical and non-canonical NLRP3 inflammasome activation in lung macrophages	20
Multifaceted roles of UFMylation in health and disease	20
Targeted VEGFA therapy in regulating early acute kidney injury and late fibrosis	20
AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage	20
Exploring the constitutive activation mechanism of the class A orphan GPR20	20
Modified citrus pectin inhibits breast cancer development in mice by targeting tumor-associated macrophage survival and polarization in hypoxic microenvironment	19
GLP-1 mimetics as a potential therapy for nonalcoholic steatohepatitis	19
Krüppel-like factors: potential roles in blood-brain barrier dysfunction and epileptogenesis	19
Correction: A novel annexin dimer targets microglial phagocytosis of astrocytes to protect the brain-blood barrier after cerebral ischemia	19
Inhibition of CD36 ameliorates mouse spinal cord injury by accelerating microglial lipophagy	19
Neuropeptide-mediated activation of astrocytes improves stress resilience in mice by modulating cortical neural synapses	19
Somatostatin receptor 2 targeting peptide modifications for peptide-drug conjugate treatment of small cell lung cancer	19
Characterization of LTr1 derived from cruciferous vegetables as a novel anti-glioma agent via inhibiting TrkA/PI3K/AKT pathway	19
NADPHnet: a novel strategy to predict compounds for regulation of NADPH metabolism via network-based methods	19
SARS-CoV-2 receptor binding domain radio-probe: a non-invasive approach for angiotensin-converting enzyme 2 mapping in mice	19
Modeling exposure-driven adverse events of EGFR TKIs in the treatment of patients with non-small cell lung cancer	19
Inhibition of HIF-prolyl hydroxylase promotes renal tubule regeneration via the reprogramming of renal proximal tubular cells	19
The PIWI-interacting RNA CRAPIR alleviates myocardial ischemia‒reperfusion injury by reducing p53-mediated apoptosis via binding to SRSF1	19
Circular RNA hsa_circ_0000288 protects against epilepsy in mice by binding to and stabilizing caprin1 protein	19
Activation of D2-like dopamine receptors improves the neuronal network and cognitive function of PPT1KI mice	18
Dl-3-n-butylphthalide promotes angiogenesis in ischemic stroke mice through upregulating autocrine and paracrine sonic hedgehog	18
ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway	18
Adiponectin receptor agonist AdipoRon modulates human and mouse platelet function	18
Signaling profiles in HEK 293T cells co-expressing GLP-1 and GIP receptors	18
Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma	18
Brigatinib, a newly discovered AXL inhibitor, suppresses AXL-mediated acquired resistance to osimertinib in EGFR-mutated non-small cell lung cancer	18
Notoginsenoside R1 protects against myocardial ischemia/reperfusion injury in mice via suppressing TAK1-JNK/p38 signaling	18
Discovery of FO-4-15, a novel 1,2,4-oxadiazole derivative, ameliorates cognitive impairments in 3×Tg mice by activating the mGluR1/CaMKIIα pathway	18
Prenatal dexamethasone exposure programs the decreased testosterone synthesis in offspring rats by low level of endogenous glucocorticoids	18
Dysregulation of iron homeostasis and methamphetamine reward behaviors in Clk1-deficient mice	18
Updates on novel pharmacotherapeutics for the treatment of nonalcoholic steatohepatitis	18
PHLDA1 contributes to hypoxic ischemic brain injury in neonatal rats via inhibiting FUNDC1-mediated mitophagy	18
Thermoregulatory pathway underlying the pyrogenic effects of prostaglandin E2 in the lateral parabrachial nucleus of male rats	18
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor	17
Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction	17
Pharmacological characterization of the small molecule 03A10 as an inhibitor of α-synuclein aggregation for Parkinson’s disease treatment	17
Serum granulosa cell-derived TNF-α promotes inflammation and apoptosis of renal tubular cells and PCOS-related kidney injury through NF-κB signaling	17
Role of thrombospondin-1 in high-salt–induced mesenteric artery endothelial impairment in rats	17
Inhibiting the transcription and replication of Ebola viruses by disrupting the nucleoprotein and VP30 protein interaction with small molecules	17
Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3	17
Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method	17
USP11 promotes renal tubular cell pyroptosis and fibrosis in UUO mice via inhibiting KLF4 ubiquitin degradation	17
A novel selective ERK1/2 inhibitor, Laxiflorin B, targets EGFR mutation subtypes in non-small-cell lung cancer	17
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice	17
Novel Caspase-1 inhibitor CZL80 improves neurological function in mice after progressive ischemic stroke within a long therapeutic time-window	17
Chemokine CCL2 promotes cardiac regeneration and repair in myocardial infarction mice via activation of the JNK/STAT3 axis	17
Differential modulation of subthalamic projection neurons by short-term and long-term electrical stimulation in physiological and parkinsonian conditions	17
124I-labeled anti-CD147 antibody for noninvasive detection of CD147-positive pan-cancers: construction and preclinical studies	17
Colchicine reduces neointima formation and VSMC phenotype transition by modulating SRF-MYOCD activation and autophagy	16
Heat shock protein family A member 8 serving as a co-activator of transcriptional factor ETV4 up-regulates PHLDA2 to promote the growth of liver cancer	16
Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson’s disease models	16
Disturbance of suprachiasmatic nucleus function improves cardiac repair after myocardial infarction by IGF2-mediated macrophage transition	16
The aminosteroid U73122 promotes oligodendrocytes generation and myelin formation	16
Author Correction: α-Galactosylceramide and its analog OCH differentially affect the pathogenesis of ISO-induced cardiac injury in mice	16
Indoxyl sulphate-TNFα axis mediates uremic encephalopathy in rodent acute kidney injury	16
MMP-9 inhibitor SB-3CT improves neurological outcomes in ischemic stroke mice by modulation of astrocytic lipid metabolism	16
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho	16
Autoimmune diseases: targets, biology, and drug discovery	16
α-MSH-catabolic enzyme prolylcarboxypeptidase in nucleus accumbens shell ameliorates stress susceptibility in mice through regulating synaptic plasticity	16
6-Methyl flavone inhibits Nogo-B expression and improves high fructose diet-induced liver injury in mice	16
Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II	16
Tetramethylpyrazine prevents liver fibrotic injury in mice by targeting hepatocyte-derived and mitochondrial DNA-enriched extracellular vesicles	16
A novel small-molecule PCSK9 inhibitor E28362 ameliorates hyperlipidemia and atherosclerosis	16
Liver receptor homolog-1: structures, related diseases, and drug discovery	16
Activation of TRPV1 receptor facilitates myelin repair following demyelination via the regulation of microglial function	16