Acta Pharmacologica Sinica

Article	Citations
Iguratimod suppresses plasma cell differentiation and ameliorates experimental Sjögren’s syndrome in mice by promoting TEC kinase degradation	243
Author Correction: Discovery of toxoflavin, a potent IRE1α inhibitor acting through structure-dependent oxidative inhibition	149
Celastrol suppresses the growth of vestibular schwannoma in mice by promoting the degradation of β-catenin	130
Single-dose methamphetamine administration impairs ORM retrieval in mice via excessive DA-mediated inhibition of PrLGlu activity	126
Identification of Licoflavone C as a cap-dependent endonuclease inhibitor against severe fever with thrombocytopenia syndrome virus	108
Otilonium bromide ameliorates pulmonary fibrosis in mice through activating phosphatase PPM1A	99
Integration of machine learning and experimental validation reveals new lipid-lowering drug candidates	97
Compound 38, a novel potent and selective antagonist of adenosine A2A receptor, enhances arousal in mice	89
MC1R and melanin-based molecular probes for theranostic of melanoma and beyond	87
Translin deletion impairs cocaine-induced locomotor sensitization and RGS8 expression in the nucleus accumbens	86
Paris saponin VII, a Hippo pathway activator, induces autophagy and exhibits therapeutic potential against human breast cancer cells	86
Reducing lipid peroxidation attenuates stress-induced susceptibility to herpes simplex virus type 1	86
Channelopathy of small- and intermediate-conductance Ca2+-activated K+ channels	81
Aspirin triggers ferroptosis in hepatocellular carcinoma cells through restricting NF-κB p65-activated SLC7A11 transcription	79
Ginsenoside Rg1 ameliorates stress-exacerbated Parkinson’s disease in mice by eliminating RTP801 and α-synuclein autophagic degradation obstacle	78
S670, an amide derivative of 3-O-acetyl-11-keto-β-boswellic acid, induces ferroptosis in human glioblastoma cells by generating ROS and inhibiting STX17-mediated fusion of autophagosome and lysosome	75
Extracellular vesicles in vascular remodeling	75
Cystathionine γ-lyase-derived H2S negatively regulates thymic egress via allosteric inhibition of sphingosine-1-phosphate lyase	75
ADT-OH inhibits malignant melanoma metastasis in mice via suppressing CSE/CBS and FAK/Paxillin signaling pathway	69
Pyroptosis and pyroptosis-inducing cancer drugs	65
The hybrid oncolytic peptide NTP-385 potently inhibits adherent cancer cells by targeting the nucleus	63
Natural product-based screening led to the discovery of a novel PXR agonist with anti-cholestasis activity	61
Satellite cell-derived exosome-mediated delivery of microRNA-23a/27a/26a cluster ameliorates the renal tubulointerstitial fibrosis in mouse diabetic nephropathy	60
Activating Wnt/β-catenin signaling by autophagic degradation of APC contributes to the osteoblast differentiation effect of soy isoflavone on osteoporotic mesenchymal stem cells	60
Zonisamide attenuates pressure overload-induced myocardial hypertrophy in mice through proteasome inhibition	59

GRK2-mediated phosphorylation and de-succinylation of PKM2 reduce macrophage glycolysis in rheumatoid arthritis	57
Role of TRPM2 in brain tumours and potential as a drug target	56
Targeted degradation of membrane and extracellular proteins with LYTACs	56
tRF3-IleAAT reduced extracellular matrix synthesis in diabetic kidney disease mice by targeting ZNF281 and inhibiting ferroptosis	54
Transport mechanism and drug discovery of human monocarboxylate transporter 1	53
Transcriptional regulation and small compound targeting of ACE2 in lung epithelial cells	53
Antagonism of histamine H3 receptor promotes angiogenesis following focal cerebral ischemia	53
Liver X receptor inverse agonist SR9243 attenuates rheumatoid arthritis via modulating glycolytic metabolism of macrophages	52
Author Correction: ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway	52
Discovery and pharmacological characterization of 1,2,3,4-tetrahydroquinoline derivatives as RORγ inverse agonists against prostate cancer	51
Sortilin deletion in the prefrontal cortex and hippocampus ameliorates depressive-like behaviors in mice via regulating ASM/ceramide signaling	51
p52-ZER6: a determinant of tumor cell sensitivity to MDM2-p53 binding inhibitors	50
143D, a novel selective KRASG12C inhibitor exhibits potent antitumor activity in preclinical models	49
Insomnia-related rodent models in drug discovery	48
Identification of pimavanserin tartrate as a potent Ca2+-calcineurin-NFAT pathway inhibitor for glioblastoma therapy	48
Trametinib, an anti-tumor drug, promotes oligodendrocytes generation and myelin formation	47
Correction to: EPHA2 feedback activation limits the response to PDEδ inhibition in KRAS-dependent cancer cells	47
TRADD-mediated pyroptosis contributes to diabetic cardiomyopathy	47
LN-439A, a novel BAP1 inhibitor, suppresses the growth of basal-like breast cancer by degrading KLF5	46
Benzimidazoles induce concurrent apoptosis and pyroptosis of human glioblastoma cells via arresting cell cycle	46
Structure basis for inhibition of SARS-CoV-2 by the feline drug GC376	44
Flavokawain B alleviates LPS-induced acute lung injury via targeting myeloid differentiation factor 2	43
FX5, a non-steroidal glucocorticoid receptor antagonist, ameliorates diabetic cognitive impairment in mice	42
Mitochondrial calcium uniporter promotes kidney aging in mice through inducing mitochondrial calcium-mediated renal tubular cell senescence	42
Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway	40
Thoracic perivascular adipose tissue inhibits VSMC apoptosis and aortic aneurysm formation in mice via the secretome of browning adipocytes	40
Chronic infusion of ELABELA alleviates vascular remodeling in spontaneously hypertensive rats via anti-inflammatory, anti-oxidative and anti-proliferative effects	40
Gastrodin promotes CNS myelinogenesis and alleviates demyelinating injury by activating the PI3K/AKT/mTOR signaling	40
Dual-responsive nanoparticles loading bevacizumab and gefitinib for molecular targeted therapy against non-small cell lung cancer	40
JOSD2 alleviates acute kidney injury through deubiquitinating SIRT7 and negativity regulating SIRT7-NF-κB inflammatory pathway in renal tubular epithelial cells	39
Author Correction: Anti-diabetic drug canagliflozin hinders skeletal muscle regeneration in mice	39
Fangchinoline-mediated autophagy inhibition amplifies antigen presentation and PD-1 blockade efficacy in lung cancer	38
Discovery of novel MIF inhibitors that attenuate microglial inflammatory activation by structures-based virtual screening and in vitro bioassays	38
Discovery of novel DprE1 inhibitors via computational bioactivity fingerprints and structure-based virtual screening	38
Deletion of p38γ attenuates ethanol consumption- and acetaminophen-induced liver injury in mice through promoting Dlg1	37
Chemistry and bioactivity of secondary metabolites from South China Sea marine fauna and flora: recent research advances and perspective	37
Correction: Chemokine CCL2 promotes cardiac regeneration and repair in myocardial infarction mice via activation of the JNK/STAT3 axis	36
14-3-3ζ inhibits maladaptive repair in renal tubules by regulating YAP and reduces renal interstitial fibrosis	36
A high-throughput screening campaign against PFKFB3 identified potential inhibitors with novel scaffolds	35
Methionine-choline deficient diet deteriorates DSS-induced murine colitis through disturbance of gut microbes and infiltration of macrophages	35
Porcupine inhibitor CGX1321 alleviates heart failure with preserved ejection fraction in mice by blocking WNT signaling	34
Selumetinib promotes coronary collateral circulation by inducing M2-like macrophage polarization following myocardial infarction	33
Antiatherosclerotic effect of dehydrocorydaline on ApoE−/− mice: inhibition of macrophage inflammation	33
Selective EZH2 inhibitor zld1039 alleviates inflammation in cisplatin-induced acute kidney injury partially by enhancing RKIP and suppressing NF-κB p65 pathway	33
Melatonin ameliorates bleomycin-induced pulmonary fibrosis via activating NRF2 and inhibiting galectin-3 expression	33
Preclinical characterization of [18F]D2-LW223: an improved metabolically stable PET tracer for imaging the translocator protein 18 kDa (TSPO) in neuroinflammatory rodent models and non-human primates	33
The diverse role of the raphe 5-HTergic systems in epilepsy	33
SGLT2 inhibitor empagliflozin promotes revascularization in diabetic mouse hindlimb ischemia by inhibiting ferroptosis	32
Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats	32
Advances in cannabinoid receptors pharmacology: from receptor structural insights to ligand discovery	32

NASH: regulatory considerations for clinical drug development and U.S. FDA approval	31
Celastrol attenuates hepatitis C virus translation and inflammatory response in mice by suppressing heat shock protein 90β	31
Ferroptosis inhibitor liproxstatin-1 alleviates metabolic dysfunction-associated fatty liver disease in mice: potential involvement of PANoptosis	30
Discovery of potential small molecular SARS-CoV-2 entry blockers targeting the spike protein	30
Oridonin ameliorates caspase-9-mediated brain neuronal apoptosis in mouse with ischemic stroke by inhibiting RIPK3-mediated mitophagy	29
Wogonin attenuates septic cardiomyopathy by suppressing ALOX15-mediated ferroptosis	29
Regulation of toll-like receptor (TLR) signaling pathways in atherosclerosis: from mechanisms to targeted therapeutics	29
RIPK1 inhibition contributes to lysosomal membrane stabilization in ischemic astrocytes via a lysosomal Hsp70.1B-dependent mechanism	29
ATF3 contributes to brucine-triggered glioma cell ferroptosis via promotion of hydrogen peroxide and iron	29
Esculetin facilitates post-stroke rehabilitation by inhibiting CKLF1-mediated neutrophil infiltration	29
Cytosolic DNA initiates a vicious circle of aging-related endothelial inflammation and mitochondrial dysfunction via STING: the inhibitory effect of Cilostazol	29
Current status and challenges in the drug treatment for fibrotic nonalcoholic steatohepatitis	29
AlphaFold3 versus experimental structures: assessment of the accuracy in ligand-bound G protein-coupled receptors	29
Discovery of a selective TRF2 inhibitor FKB04 induced telomere shortening and senescence in liver cancer cells	29
Therapeutic potential and pharmacological mechanisms of Traditional Chinese Medicine in gout treatment	28
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2	28
Hypertrophic preconditioning attenuates post-myocardial infarction injury through deacetylation of isocitrate dehydrogenase 2	27
Z16b, a natural compound from Ganoderma cochlear is a novel RyR2 stabilizer preventing catecholaminergic polymorphic ventricular tachycardia	27
Phenethyl isothiocyanate inhibits metastasis potential of non-small cell lung cancer cells through FTO mediated TLE1 m6A modification	27
Proteomic characterization of post-translational modifications in drug discovery	27
ML365 inhibits TWIK2 channel to block ATP-induced NLRP3 inflammasome	27
Cardiomyocyte peroxisome proliferator-activated receptor α prevents septic cardiomyopathy via improving mitochondrial function	26
Endothelial dysfunction: mechanisms and contribution to diseases	26
Co-inhibition of RAGE and TLR4 sensitizes pancreatic cancer to irreversible electroporation in mice by disrupting autophagy	26
Dezocine as a potent analgesic: overview of its pharmacological characterization	26
Long-term running exercise alleviates cognitive dysfunction in APP/PSEN1 transgenic mice via enhancing brain lysosomal function	25
Discovery of a nitroaromatic nannocystin with potent in vivo anticancer activity against colorectal cancer by targeting AKT1	25
CP-25 enhances OAT1-mediated absorption of methotrexate in synoviocytes of collagen-induced arthritis rats	25
Skullcapflavone II, a novel NQO1 inhibitor, alleviates aristolochic acid I-induced liver and kidney injury in mice	25
ROCK1 inhibition improves wound healing in diabetes via RIPK4/AMPK pathway	25
Scutellarin suppresses triple-negative breast cancer metastasis by inhibiting TNFα-induced vascular endothelial barrier breakdown	25
Estrogen-dependent KCa1.1 modulation is essential for retaining neuroexcitation of female-specific subpopulation of myelinated Ah-type baroreceptor neurons in rats	25
Correction: Empagliflozin and liraglutide ameliorate HFpEF in mice via augmenting the Erbb4 signaling pathway	24
Author Correction: Apolipoprotein C1 promotes glioblastoma tumorigenesis by reducing KEAP1/NRF2 and CBS-regulated ferroptosis	24
c-FLIP promotes drug resistance in non-small-cell lung cancer cells via upregulating FoxM1 expression	24
Dorsal raphe GABA-ergic neurons regulate the susceptibility to social transfer of pain in mice	24
Anti-diabetic drug canagliflozin hinders skeletal muscle regeneration in mice	24
Development of PI3Kγ selective inhibitors: the strategies and application	24
Thioridazine protects against disturbed flow-induced atherosclerosis by inhibiting RhoA/YAP-mediated endothelial inflammation	24
Adaptor protein Src-homology 2 domain containing E (SH2E) deficiency induces heart defect in zebrafish	24
Celastrol inhibits the DPYSL2-JAK/STAT pathway by targeting mito-IDHs mediated mitochondrial metabolism to exhaust breast cancer	23
(+)-Borneol enantiomer ameliorates epileptic seizure via decreasing the excitability of glutamatergic transmission	23
Targeting PI3Kα overcomes resistance to KRasG12C inhibitors mediated by activation of EGFR and/or IGF1R	23
Revisiting the role of GDF15 in atherosclerosis in mouse and human	23
The role of microglia in neurodegenerative diseases: from the perspective of ferroptosis	23
Peptidoglycan isolated from the fruit of Lycium barbarum alleviates liver fibrosis in mice by regulating the TGF-β/Smad7 signaling and gut microbiota	22
Novel treatment for refractory rheumatoid arthritis with total glucosides of paeony and nobiletin codelivered in a self-nanoemulsifying drug delivery system	22
Dehydrocorydaline maintains the vascular smooth muscle cell contractile phenotype by upregulating Spta1	22
GFPBW1, a β-glucan from Grifola frondosa as vaccine adjuvant: APCs activation and maturation	22
Electrophysiological characterization of human KCNT1 channel modulators and the therapeutic potential of hydroquinine and tipepidine in KCNT1 mutation-associated epilepsy mouse model	22
IFN-α inhibits HBV transcription and replication by promoting HDAC3-mediated de-2-hydroxyisobutyrylation of histone H4K8 on HBV cccDNA minichromosome in liver	22
zDHHC20-driven S-palmitoylation of CD80 is required for its costimulatory function	22
Bile acid and receptors: biology and drug discovery for nonalcoholic fatty liver disease	22
Discovery of SARS-CoV-2-E channel inhibitors as antiviral candidates	22
Development of orthotopic mouse models for mid-low rectal cancer	22
Ainsliadimer C, a disesquiterpenoid isolated from Ainsliaea macrocephala, ameliorates inflammatory responses in adipose tissue via Sirtuin 1-NLRP3 inflammasome axis	22
PRMT5 confers lipid metabolism reprogramming, tumour growth and metastasis depending on the SIRT7-mediated desuccinylation of PRMT5 K387 in tumours	22
Mitochondrial-derived damage-associated molecular patterns amplify neuroinflammation in neurodegenerative diseases	21
Cardiovascular adverse effects of antiviral therapies for COVID-19: Evidence and plausible mechanisms	21
Asiatic acid ameliorates doxorubicin-induced cardiotoxicity by promoting FPN-mediated iron export and inhibiting ferroptosis	21
Endothelial deubiquinatase YOD1 mediates Ang II-induced vascular endothelial-mesenchymal transition and remodeling by regulating β-catenin	21
NFAT inhibitor 11R-VIVIT ameliorates mouse renal fibrosis after ischemia-reperfusion-induced acute kidney injury	21
Bergenin, a PPARγ agonist, inhibits Th17 differentiation and subsequent neutrophilic asthma by preventing GLS1-dependent glutaminolysis	21
Poria cocos: traditional uses, triterpenoid components and their renoprotective pharmacology	21
The novel indomethacin derivative CZ-212-3 exerts antitumor effects on castration-resistant prostate cancer by degrading androgen receptor and its variants	21
Caffeic acid phenethyl ester suppresses intestinal FXR signaling and ameliorates nonalcoholic fatty liver disease by inhibiting bacterial bile salt hydrolase activity	21
Cyclic GMP-AMP synthase recognizes the physical features of DNA	20
Targeting cholesterol metabolism: a promising therapy strategy for cancer	20
Effect of autoinduction and food on the pharmacokinetics of furmonertinib and its active metabolite characterized by a population pharmacokinetic model	20
Aspirin modulates succinylation of PGAM1K99 to restrict the glycolysis through NF-κB/HAT1/PGAM1 signaling in liver cancer	20
Atypical chemokine receptor 3 induces colorectal tumorigenesis in mice by promoting β-arrestin-NOLC1-fibrillarin-dependent rRNA biogenesis	20
DZ2002 alleviates corneal angiogenesis and inflammation in rodent models of dry eye disease via regulating STAT3-PI3K-Akt-NF-κB pathway	20
Gentiopicroside ameliorates psoriasis-like skin lesions in mice via regulating the Keap1-Nrf2 pathway and inhibiting keratinocyte activation	20
Author Correction: Small molecule LX2343 ameliorates cognitive deficits in AD model mice by targeting both amyloid β production and clearance	20
Age-dependent alterations in key components of the nigrostriatal dopaminergic system and distinct motor phenotypes	20
Chalcone derivatives ameliorate lipopolysaccharide-induced acute lung injury and inflammation by targeting MD2	20
AXL antibody and AXL-ADC mediate antitumor efficacy via targeting AXL in tumor-intrinsic epithelial-mesenchymal transition and tumor-associated M2-like macrophage	19
Multifaceted roles of UFMylation in health and disease	19
Hypocrellin A from an ethnic medicinal fungus protects against NLRP3-driven gout in mice by suppressing inflammasome activation	19
Pharmacological inhibition of FABP7 by MF 6 counteracts cerebellum dysfunction in an experimental multiple system atrophy mouse model	19

Targeted VEGFA therapy in regulating early acute kidney injury and late fibrosis	19
Inhibiting the Otub1/phosphorylated STAT3 axis for the treatment of non-small cell lung cancer	19
Targeting cyclin-dependent kinase 9 in cancer therapy	19
Prenatal dexamethasone exposure impairs rat blood-testis barrier function and sperm quality in adult offspring via GR/KDM1B/FSTL3/TGFβ signaling	19
Parkin deficiency promotes liver cancer metastasis by TMEFF1 transcription activation via TGF-β/Smad2/3 pathway	19
GPR41 deficiency aggravates type 1 diabetes in streptozotocin-treated mice by promoting dendritic cell maturation	19
Urolithin A ameliorates obesity-induced metabolic cardiomyopathy in mice via mitophagy activation	19
Exploring the constitutive activation mechanism of the class A orphan GPR20	19
Cardiac-specific deletion of BRG1 ameliorates ventricular arrhythmia in mice with myocardial infarction	19
Novel insights into NOD-like receptors in renal diseases	19
Chronic β-adrenergic stress contributes to cardiomyopathy in rodents with collagen-induced arthritis	19
Tetrandrine alleviates silicosis by inhibiting canonical and non-canonical NLRP3 inflammasome activation in lung macrophages	19
Luteolin ameliorates chronic stress-induced depressive-like behaviors in mice by promoting the Arginase-1+ microglial phenotype via a PPARγ-dependent mechanism	19
Dl-3-n-butylphthalide promotes angiogenesis in ischemic stroke mice through upregulating autocrine and paracrine sonic hedgehog	18
Inhibition of HIF-prolyl hydroxylase promotes renal tubule regeneration via the reprogramming of renal proximal tubular cells	18
The PIWI-interacting RNA CRAPIR alleviates myocardial ischemia‒reperfusion injury by reducing p53-mediated apoptosis via binding to SRSF1	18
Signaling profiles in HEK 293T cells co-expressing GLP-1 and GIP receptors	18
ADH1C inhibits progression of colorectal cancer through the ADH1C/PHGDH /PSAT1/serine metabolic pathway	18
Pyk2 inhibition attenuates hypoxic-ischemic brain injury in neonatal mice	18
A novel and effective approach to generate germline-like monoclonal antibodies by integration of phage and mammalian cell display platforms	18
Activation of D2-like dopamine receptors improves the neuronal network and cognitive function of PPT1KI mice	18
Prenatal dexamethasone exposure programs the decreased testosterone synthesis in offspring rats by low level of endogenous glucocorticoids	18
NADPHnet: a novel strategy to predict compounds for regulation of NADPH metabolism via network-based methods	18
Neuropeptide-mediated activation of astrocytes improves stress resilience in mice by modulating cortical neural synapses	18
SARS-CoV-2 receptor binding domain radio-probe: a non-invasive approach for angiotensin-converting enzyme 2 mapping in mice	18
PHLDA1 contributes to hypoxic ischemic brain injury in neonatal rats via inhibiting FUNDC1-mediated mitophagy	18
Inhibition of CD36 ameliorates mouse spinal cord injury by accelerating microglial lipophagy	18
Correction: A novel annexin dimer targets microglial phagocytosis of astrocytes to protect the brain-blood barrier after cerebral ischemia	18
Krüppel-like factors: potential roles in blood-brain barrier dysfunction and epileptogenesis	17
Brigatinib, a newly discovered AXL inhibitor, suppresses AXL-mediated acquired resistance to osimertinib in EGFR-mutated non-small cell lung cancer	17
Notoginsenoside R1 protects against myocardial ischemia/reperfusion injury in mice via suppressing TAK1-JNK/p38 signaling	17
Deep learning enables the discovery of a novel cuproptosis-inducing molecule for the inhibition of hepatocellular carcinoma	17
Circular RNA hsa_circ_0000288 protects against epilepsy in mice by binding to and stabilizing caprin1 protein	17
Updates on novel pharmacotherapeutics for the treatment of nonalcoholic steatohepatitis	17
Characterization of LTr1 derived from cruciferous vegetables as a novel anti-glioma agent via inhibiting TrkA/PI3K/AKT pathway	17
Modified citrus pectin inhibits breast cancer development in mice by targeting tumor-associated macrophage survival and polarization in hypoxic microenvironment	17
Dysregulation of iron homeostasis and methamphetamine reward behaviors in Clk1-deficient mice	17
Adiponectin receptor agonist AdipoRon modulates human and mouse platelet function	17
GLP-1 mimetics as a potential therapy for nonalcoholic steatohepatitis	17
Colchicine reduces neointima formation and VSMC phenotype transition by modulating SRF-MYOCD activation and autophagy	16
124I-labeled anti-CD147 antibody for noninvasive detection of CD147-positive pan-cancers: construction and preclinical studies	16
MMP-9 inhibitor SB-3CT improves neurological outcomes in ischemic stroke mice by modulation of astrocytic lipid metabolism	16
Inhibiting the transcription and replication of Ebola viruses by disrupting the nucleoprotein and VP30 protein interaction with small molecules	16
Chemokine CCL2 promotes cardiac regeneration and repair in myocardial infarction mice via activation of the JNK/STAT3 axis	16
Novel Caspase-1 inhibitor CZL80 improves neurological function in mice after progressive ischemic stroke within a long therapeutic time-window	16
Discovery of FO-4-15, a novel 1,2,4-oxadiazole derivative, ameliorates cognitive impairments in 3×Tg mice by activating the mGluR1/CaMKIIα pathway	16
Role of thrombospondin-1 in high-salt–induced mesenteric artery endothelial impairment in rats	16
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor	16
Pentapeptide PYRAE triggers ER stress-mediated apoptosis of breast cancer cells in mice by targeting RHBDF1-BiP interaction	16
Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II	16
Differential modulation of subthalamic projection neurons by short-term and long-term electrical stimulation in physiological and parkinsonian conditions	16
Thermoregulatory pathway underlying the pyrogenic effects of prostaglandin E2 in the lateral parabrachial nucleus of male rats	16
Aberrant neuronal excitation promotes neuroinflammation in the primary motor cortex of ischemic stroke mice	16
Discovery of novel GluN1/GluN3A NMDA receptor inhibitors using a deep learning-based method	16
USP11 promotes renal tubular cell pyroptosis and fibrosis in UUO mice via inhibiting KLF4 ubiquitin degradation	16
A novel selective ERK1/2 inhibitor, Laxiflorin B, targets EGFR mutation subtypes in non-small-cell lung cancer	16
Roflupram protects against rotenone-induced neurotoxicity and facilitates α-synuclein degradation in Parkinson’s disease models	16
Berberine remodels adipose tissue to attenuate metabolic disorders by activating sirtuin 3	15
A novel small-molecule PCSK9 inhibitor E28362 ameliorates hyperlipidemia and atherosclerosis	15
Serum granulosa cell-derived TNF-α promotes inflammation and apoptosis of renal tubular cells and PCOS-related kidney injury through NF-κB signaling	15
TGFβR-1/ALK5 inhibitor RepSox induces enteric glia-to-neuron transition and influences gastrointestinal mobility in adult mice	15
Author Correction: α-Galactosylceramide and its analog OCH differentially affect the pathogenesis of ISO-induced cardiac injury in mice	15
Heat shock protein family A member 8 serving as a co-activator of transcriptional factor ETV4 up-regulates PHLDA2 to promote the growth of liver cancer	15
Tetramethylpyrazine prevents liver fibrotic injury in mice by targeting hepatocyte-derived and mitochondrial DNA-enriched extracellular vesicles	15
Indoxyl sulphate-TNFα axis mediates uremic encephalopathy in rodent acute kidney injury	15
Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho	15
Pharmacological characterization of the small molecule 03A10 as an inhibitor of α-synuclein aggregation for Parkinson’s disease treatment	15
Luteolin alleviates cognitive impairment in Alzheimer’s disease mouse model via inhibiting endoplasmic reticulum stress-dependent neuroinflammation	15