Acta Biochimica et Biophysica Sinica

Article	Citations
ROS signaling cascades: dual regulations for osteoclast and osteoblast	87
TBK1, a central kinase in innate immune sensing of nucleic acids and beyond	58
A modified pCas/pTargetF system for CRISPR-Cas9-assisted genome editing in Escherichia coli	58
Metformin induces ferroptosis by targeting miR-324-3p/GPX4 axis in breast cancer	54
Exosomal piRNA profiling revealed unique circulating piRNA signatures of cholangiocarcinoma and gallbladder carcinoma	46
Mesenchymal stem cell-derived exosomal miR-21a-5p promotes M2 macrophage polarization and reduces macrophage infiltration to attenuate atherosclerosis	43
Piezo1 regulates migration and invasion of breast cancer cells via modulating cell mechanobiological properties	36
A mini-review on ion fluxes that regulate NLRP3 inflammasome activation	33
Exosomal LINC00355 derived from cancer-associated fibroblasts promotes bladder cancer cell resistance to cisplatin by regulating miR-34b-5p/ABCB1 axis	32
Isoliquiritigenin inhibits TGF-<roman>β</roman>1-induced fibrogenesis through activating autophagy via PI3K/AKT/mTOR pathway in MRC-5 cells	30
Cardiovascular disease in patients with COVID-19: evidence from cardiovascular pathology to treatment	30
Epigenetics in the pathogenesis of diabetic nephropathy	29
Resveratrol induces AMPK and mTOR signaling inhibition-mediated autophagy and apoptosis in multiple myeloma cells	29
Exosomal lncRNA FOXD3-AS1 upregulates ELAVL1 expression and activates PI3K/Akt pathway to enhance lung cancer cell proliferation, invasion, and 5-fluorouracil resistance	29
Mitochondrial metabolism in regulating macrophage polarization: an emerging regulator of metabolic inflammatory diseases	28
Collagen prolyl 4-hydroxylases modify tumor progression	26
Preparation, characterization, and evaluation of antioxidant activity and bioavailability of a self-nanoemulsifying drug delivery system (SNEDDS) for buckwheat flavonoids	26
Exposure to dibutyl phthalate impairs lipid metabolism and causes inflammation via disturbing microbiota-related gut–liver axis	26
lncRNA NEAT1 prompts autophagy and apoptosis in MPTP-induced Parkinson’s disease by impairing miR-374c-5p	26
Exosomal lncRNA-p21 derived from mesenchymal stem cells protects epithelial cells during LPS-induced acute lung injury by sponging miR-181	26
Lipid metabolism in cartilage and its diseases: a concise review of the research progress	25
Role and effect of vein-transplanted human umbilical cord mesenchymal stem cells in the repair of diabetic foot ulcers in rats	25
miR-338-5p inhibits cell growth and migration via inhibition of the METTL3/m6A/c-Myc pathway in lung cancer	24
Upregulation of miR-133a by adiponectin inhibits pyroptosis pathway and rescues acute aortic dissection	23
miR-100-5p in human umbilical cord mesenchymal stem cell-derived exosomes mediates eosinophilic inflammation to alleviate atherosclerosis via the FZD5/Wnt/β-catenin pathway	22

Identification of lipid metabolism-related genes as prognostic indicators in papillary thyroid cancer	22
Resveratrol inhibits necroptosis by mediating the TNF-α/RIP1/RIP3/MLKL pathway in myocardial hypoxia/reoxygenation injury	21
NEAT1/miR-140-3p/MAPK1 mediates the viability and survival of coronary endothelial cells and affects coronary atherosclerotic heart disease	21
Long non-coding RNA SNHG14 aggravates LPS-induced acute kidney injury through regulating miR-495-3p/HIPK1	21
PDGF-AA promotes cell-to-cell communication in osteocytes through PI3K/Akt signaling pathway	20
Long non-coding RNA LINC-PINT attenuates paclitaxel resistance in triple-negative breast cancer cells via targeting the RNA-binding protein NONO	19
Comprehensive analysis of circular RNA expression profiles in cisplatin-resistant non-small cell lung cancer cell lines	19
Baicalein suppresses vasculogenic mimicry through inhibiting RhoA/ROCK expression in lung cancer A549 cell line	19
lncRNA NEAT1 promotes the Taxol resistance of breast cancer via sponging the miR-23a-3p-FOXA1 axis	18
Comparison of the differentiation of dental pulp stem cells and periodontal ligament stem cells into neuron-like cells and their effects on focal cerebral ischemia	18
Regulation of alveolar type 2 stem/progenitor cells in lung injury and regeneration	17
Nsp2 has the potential to be a drug target revealed by global identification of SARS-CoV-2 Nsp2-interacting proteins	16
Regulation and functions of the Hippo pathway in stemness and differentiation	16
miR-20b suppresses mitochondrial dysfunction-mediated apoptosis to alleviate hyperoxia-induced acute lung injury by directly targeting MFN1 and MFN2	16
HOTAIRM1 promotes osteogenic differentiation and alleviates osteoclast differentiation by inactivating the NF-κB pathway	16
Three-dimensional silk fibroin scaffolds enhance the bone formation and angiogenic differentiation of human amniotic mesenchymal stem cells: a biocompatibility analysis	16
22q11.2 deletion syndrome and schizophrenia	16
Exosomal LINC00355 derived from cancer-associated fibroblasts promotes bladder cancer cell proliferation and invasion by regulating miR-15a-5p/HMGA2 axis	16
PRPF19 promotes tongue cancer growth and chemoradiotherapy resistance	16
Exosomes from adipose-derived mesenchymal stem cells promote survival of fat grafts by regulating macrophage polarization via let-7c	15
CCL26 is upregulated by nab-paclitaxel in pancreatic cancer–associated fibroblasts and promotes PDAC invasiveness through activation of the PI3K/AKT/mTOR pathway	15
Quercetin promotes human epidermal stem cell proliferation through the estrogen receptor/<bold><roman>β</roman></bold>-catenin/c-Myc/cy	15
Rapid and accurate detection of African swine fever virus by DNA endonuclease-targeted CRISPR trans reporter assay	15
Role of miR-302/367 cluster in human physiology and pathophysiology	14
Histidine ameliorates elastase- and lipopolysaccharide-induced lung inflammation by inhibiting the activation of the NLRP3 inflammasome	14
Inhibition of lipogenesis and induction of apoptosis by valproic acid in prostate cancer cells via the C/EBPα/SREBP-1 pathway	14
FOXO1 and FOXO3a sensitize non-small-cell lung cancer cells to cisplatin-induced apoptosis independent of Bim	14
N-methyladenosine methyltransferase plays a role in hypoxic preconditioning partially through the interaction with lncRNA H19	14
High glucose inhibits vascular endothelial Keap1/Nrf2/ARE signal pathway via downregulation of monomethyltransferase SET8 expression	14
hsa_circ_0062019 promotes the proliferation, migration, and invasion of prostate cancer cells via the miR-195-5p/HMGA2 axis	14
Osteoblasts induce glucose-derived ATP perturbations in chondrocytes through noncontact communication	14
Prognostic SLC family genes promote cell proliferation, migration, and invasion in hepatocellular carcinoma	13
miR-20b-5p attenuates hypoxia-induced apoptosis in cardiomyocytes via the HIF-1α/NF-κB pathway	13
Phospholipase C Delta 3 inhibits apoptosis and promotes proliferation, migration, and invasion of thyroid cancer cells via Hippo pathway	13
LncRNA LIMT (LINC01089) contributes to sorafenib chemoresistance via regulation of miR-665 and epithelial to mesenchymal transition in hepatocellular carcinoma cells	13
Epidermal growth factor receptor promotes tumor progression and contributes to gemcitabine resistance in osteosarcoma	13
NLRP3 inflammasome activation mechanism and its role in autoimmune liver disease	13
Paclitaxel-loaded and folic acid-modified PLGA nanomedicine with glutathione response for the treatment of lung cancer	13
Interleukin 1 beta-induced chloride currents are important in osteoarthritis onset: an in vitro study	13
Bi-allelic mutations in DNAH7 cause asthenozoospermia by impairing the integrality of axoneme structure	12
Liver cancer stem cells as a hierarchical society: yes or no?	12
DJ-1 is involved in the multidrug resistance of SGC7901 gastric cancer cells through PTEN/PI3K/Akt/Nrf2 pathway	12
Multiparametric atomic force microscopy imaging of single native exosomes	12
The application of ubiquitin ligases in the PROTAC drug design	12
PBK/TOPK promotes chemoresistance to oxaliplatin in hepatocellular carcinoma cells by regulating PTEN	12
Circular RNA SMARCA5 suppressed non-small cell lung cancer progression by regulating miR-670-5p/RBM24 axis	12
STAM2 knockdown inhibits proliferation, migration, and invasion by affecting the JAK2/STAT3 signaling pathway in gastric cancer	12
Molecular diversification of antimicrobial peptides from the wolf spider venom based on peptidomic, transcriptomic, and bioinformatic analyses	12
mTOR pathway regulates the differentiation of peripheral blood Th2/Treg cell subsets in patients with pemphigus vulgaris	12
Effect of silicon-doped calcium phosphate cement on angiogenesis based on controlled macrophage polarization	12

Overexpression CPT1A reduces lipid accumulation via PPARα/CD36 axis to suppress the cell proliferation in ccRCC	12
Roles of NPAS2 in circadian rhythm and disease	12
Resveratrol induces proliferation in preosteoblast cell MC3T3-E1 via GATA-1 activating autophagy	12
Long noncoding RNA CYTOR triggers gastric cancer progression by targeting miR-103/RAB10	12
LncRNA HOTAIR promotes endometrial fibrosis by activating TGF-β1/Smad pathway	12
SNHG1 functions as an oncogenic lncRNA and promotes osteosarcoma progression by up-regulating S100A6 via<?A3B2 ACK?>miR-493-5p	12
Exogenous hydrogen sulfide inhibits apoptosis by regulating endoplasmic reticulum stress–autophagy axis and improves myocardial reconstruction after acute myocardial infarction	12
Retardant effect of dihydroartemisinin on ulcerative colitis in a JAK2/STAT3-dependent manner	11
Decreased dynamin-related protein 1-related mitophagy induces myocardial apoptosis in the aging heart	11
BIG1 mediates sepsis-induced lung injury by modulating lipid raft-dependent macrophage inflammatory responses	11
A novel humanized MUC1 antibody–drug conjugate for the treatment of trastuzumab-resistant breast cancer	11
Overexpression of miR-431 attenuates hypoxia/reoxygenation-induced myocardial damage via autophagy-related 3	11
Interleukin-5 promotes ATP-binding cassette transporter A1 expression through miR-211/JAK2/STAT3 pathways in THP-1-dervied macrophages	11
Extracellular-superoxide dismutase DNA methylation promotes oxidative stress in homocysteine-induced atherosclerosis	11
Inhibition of miR-144-3p exacerbates non-small cell lung cancer progression by targeting CEP55	11
The inhibitory effect of microRNA-1827 on anoikis resistance in lung adenocarcinoma A549 cells via targeting caveolin-1	11
PAQR4 promotes the development of hepatocellular carcinoma by activating PI3K/AKT pathway	11
Elevated ZIPK is required for TNF-α-induced cell adhesion molecule expression and leucocyte adhesion in endothelial cells	10
MEF2C ameliorates learning, memory, and molecular pathological changes in Alzheimer’s disease <italic>in vivo</italic> and<?A3B2 ACK?><italic	10
Effect of TrkB-PLC/IP3 pathway on intestinal inflammatory factors and enterocyte apoptosis in mice with colitis	10
Stattic sensitizes osteosarcoma cells to epidermal growth factor receptor inhibitors via blocking the interleukin 6-induced STAT3 pathway	10
LINC00891 regulated by miR-128-3p/GATA2 axis impedes lung cancer cell proliferation, invasion and EMT by inhibiting RhoA pathway	10
ARRB2 promotes colorectal cancer growth through triggering WTAP	10
Downregulation of LINC01296 suppresses non-small-cell lung cancer via targeting miR-143-3p/ATG2B	10
Evaluation of the immunomodulatory effects of C<sub>9-13</sub>-CPs in macrophages	10
Enterorenal crosstalks in diabetic nephropathy and novel therapeutics targeting the gut microbiota	10
Recent advances of NEAT1-miRNA interactions in cancer	10
Parkin deficiency accentuates chronic alcohol intake-induced tissue injury and autophagy defects in brain, liver and skeletal muscle	10
The antiatherogenic function of kallistatin and its potential mechanism	10
2-Bromopalmitate attenuates inflammatory pain by maintaining mitochondrial fission/fusion balance and function	10
DNA damage and repair in the hematopoietic system	10
Long non-coding RNA BACE1-AS plays an oncogenic role in hepatocellular carcinoma cells through miR-214-3p/APLN axis	10
Mutations in DNAH8 contribute to multiple morphological abnormalities of sperm flagella and male infertility	10
Bacterial MerR family transcription regulators: activation<?A3B2 ACK?>by distortion	10
Tamoxifen attenuates reactive astrocyte-induced brain metastasis and drug resistance through the IL-6/STAT3 signaling pathway	9
Elevated miR-10a-5p facilitates cell cycle and restrains adipogenic differentiation via targeting Map2k6 and Fasn, respectively	9
Amygdalin attenuates PM2.5-induced human umbilical vein endothelial cell injury via the TLR4/NF-κB and Bcl-2/Bax signaling pathways	9
Knockdown of Nav1.5 inhibits cell proliferation, migration and invasion via Wnt/-catenin signaling pathway in oral squamous cell carcinoma	9
Inhibition of the lncRNA DANCR attenuates cardiomyocyte injury induced by oxygen-glucose deprivation via the miR-19a-3p/MAPK1 axis	9
IL1RN promotes osteoblastic differentiation via interacting with ITGB3 in osteoporosis	9
Glucagon-like peptide 1 reverses myocardial hypertrophy through cAMP/PKA/RhoA/ROCK2 signaling	9
Novel role of LINC01013/miR-6795-5p/FMNL3 axis in the regulation of hepatocellular carcinoma stem cell features	9
Ginsenoside Rh2 inhibits breast cancer cell growth via<?A3B2 ACK?>ERβ-TNFα pathway	9
Effect of Sox9 on TGF-β1-mediated atrial fibrosis	9
miR-150 regulates glucose utilization through targeting GLUT4 in insulin-resistant cardiomyocytes	9
Atorvastatin attenuates surgery-induced BBB disruption and cognitive impairment partly by suppressing NF-κB pathway and NLRP3 inflammasome activation in aged mice	9
miR-23b-5p promotes the chemosensitivity of temozolomide via negatively regulating TLR4 in glioma	9
BIX-01294-enhanced chemosensitivity in nasopharyngeal carcinoma depends on autophagy-induced pyroptosis	9
miR-3677-3p promotes hepatocellular carcinoma progression via inhibiting GSK3β	9
USP14 promotes pyroptosis of human annulus fibrosus cells derived from patients with intervertebral disc degeneration through deubiquitination of NLRP3	9
Guanine nucleotide-binding protein subunit beta-4 promotes gastric cancer progression via activating Erk1/2	9
Circ_002059 suppresses cell proliferation and migration of gastric cancer via miR-182/MTSS1 axis	9
The functions of CD4 T-helper lymphocytes in chronic obstructive pulmonary disease	9
Amplification and expression of c-MET correlate with poor prognosis of patients with gastric cancer and upregulate the expression of PDL1	9
1,25-(OH)D protects pancreatic beta cells against HO-induced apoptosis through inhibiting the PERK-ATF4-CHOP pathway	9
Folic acid supplement rescues ethanol-induced developmental defects in the zebrafish embryos	9
<bold> <roman>β</roman> </bold>-Cypermethrin promotes the adipogenesis of 3T3-L1 cells via inducing autophagy and shaping an adipogenes	9
A novel mannose-binding lectin from with anti-fungal and anti-tumor activities	8
Targeting UPR branches, a potential strategy for enhancing efficacy of cancer chemotherapy	8
Melatonin regulates proliferation and apoptosis of endometrial stromal cells via MT1	8
TNF-α inhibits fibrosis and migration of fibroblasts in hypertrophic scar by miR-141-3p	8
miR-335-5p regulates the proliferation, migration and phenotypic switching of vascular smooth muscle cells in aortic dissection by directly regulating SP1	8
The role of mechano growth factor in chondrocytes and cartilage defects: a concise review	8
miR-195-5p exerts tumor-suppressive functions in human lung cancer cells through targeting TrxR2	8
Impact of mitochondrial aldehyde dehydrogenase 2 on cognitive impairment in the AD model mouse	8
Overexpression of LPCAT1 enhances endometrial cancer stemness and metastasis by changing lipid components and activating TGF-β/Smad2/3 signaling pathway	8
Identification of HOXA10 target genes in human endometrial stromal cells by RNA-seq analysis	8
circStrn3 is involved in bone cancer pain regulation in a rat model	8
Exosomes derived from human umbilical cord mesenchymal stem cells reduce tendon injuries via the miR-27b-3p/ARHGAP5/RhoA signaling pathway	8
Hypoxia-induced RBBP7 promotes esophagus cancer progression by inducing CDK4 expression	8
Geniposide improves insulin resistance through AMPK-mediated Txnip protein degradation in 3T3-L1 adipocytes	8
Nucleotide excision repair: a versatile and smart toolkit	8
Interleukin 35 protects cardiomyocytes following ischemia/reperfusion-induced apoptosis via activation of mitochondrial STAT3	8
Acetoacetate promotes muscle cell proliferation via the miR-133b/SRF axis through the Mek-Erk-MEF2 pathway	8
Silencing of ER-resident oxidoreductase PDIA3 inhibits malignant biological behaviors of multidrug-resistant gastric cancer	8
<italic>Astragalus</italic> polysaccharide regulates brown adipogenic differentiation through miR-1258-5p-modulated cut-like homeobox 1 expression	8
AID function in somatic hypermutation and class switch recombination	8
Excessive apoptosis and ROS induced by ethionine affect neural cell viability and differentiation	8
miR-378 and its host gene <italic>Ppargc1<bold>β</bold></italic> exhibit independent expression in mouse skeletal muscle	7
Novel application of bergapten and quercetin with anti-bacterial, osteogenesis-potentiating, and anti-inflammation tri-effects	7

<italic>MCU</italic> knockdown in hippocampal neurons improves memory performance of an Alzheimer’s disease mouse model	7
Eupalinolide B inhibits hepatic carcinoma by inducing ferroptosis and ROS-ER-JNK pathway	7
Association between obstructive sleep apnea and cardiovascular diseases	7
PSPC1 regulates CHK1 phosphorylation through phase separation and participates in mouse oocyte maturation	7
circ-BPTF serves as a miR-486-5p sponge to regulate CEMIP and promotes hypoxic pulmonary arterial smooth muscle cell proliferation in COPD	7
Acidic microenvironment enhances MT1-MMP-mediated cancer cell motility through integrin β1/cofilin/F-actin axis	7
Single-cell analysis reveals that cancer-associated fibroblasts stimulate oral squamous cell carcinoma invasion via the TGF-β/Smad pathway	7
Protective mechanisms of Agrimonia pilosa Ledeb in dextran sodium sulfate-induced colitis as determined by a network pharmacology approach	7
miR-30a-5p promotes glomerular podocyte <?A3B2 tlsb=-0.06w?>apoptosis via DNMT1-mediated hypermethylation under hyperhomocysteinemia<?A3B2 tlsb?>	7
Chromobox homolog 4 overexpression inhibits TNF-α-induced matrix catabolism and senescence by suppressing activation of NF-κB signaling pathway in nucleus pulposus cells	7
Propofol differentially induces unconsciousness and respiratory depression through distinct interactions between GABA<sub>A</sub> receptor and GABAergic neuron in correspon	7
Successive treatment with naltrexone induces epithelial–mesenchymal transition and facilitates the malignant biological behaviors of bladder cancer cells	7
SETD8 induces stemness and epithelial–mesenchymal transition of pancreatic cancer cells by regulating ROR1 expression	7
miR-199b-5p enhances the proliferation of medullary thymic epithelial cells via regulating Wnt signaling by targeting	7
Dasatinib inhibits proliferation of liver cancer cells, but activation of Akt/mTOR compromises dasatinib as a cancer drug	7
Neuritin promotes angiogenesis through inhibition of DLL4/Notch signaling pathway	7
Induction of multiple subroutines of regulated necrosis in murine macrophages by natural BH3-mimetic gossypol	7
HMGB1-mediated autophagy promotes gefitinib resistance in human non-small cell lung cancer	7
Silencing of lncRNA LBX2-AS1 suppresses glioma cell proliferation and metastasis through the Akt/GSK3β pathway	7
Epicatechin gallate prevents the de novo synthesis of fatty acid and the migration of prostate cancer cells	7
Probucol decreases homocysteine-stimulated CRP production in rat aortic smooth muscle cells via regulating HO-1/NADPH oxidase/ROS/p38 pathway	7
Suppression of microRNA-155 exerts an anti-inflammatory effect on CD4<sup>+</sup> T cell-mediated inflammatory response in the pathogenesis of atherosclerosis	7
Effects of edpetiline from Fritillaria on inflammation and oxidative stress induced by LPS stimulation in RAW264.7 macrophages	7
DNA double-strand break repair and nucleic acid-related immunity	7
miR-4530 inhibits the malignant biological behaviors of human glioma cells by directly targeting	7
miR-28-5p targets MTSS1 to regulate cell proliferation and apoptosis in esophageal cancer	7
Activation of anterior thalamic reticular nucleus GABAergic neurons promotes arousal from propofol anesthesia in mice	7
Glucagon-like peptide-1 attenuates cardiac hypertrophy via the AngII/AT1R/ACE2 and AMPK/mTOR/p70S6K pathways	7
SCM-198 ameliorates endometrial inflammation via suppressing the LPS-JNK-cJUN/cFOS-TLR4-NF-κB pathway	7
AMPKα1 regulates transcription through H2B O-GlcNAcylation during brown adipogenesis	7
Berberine mitigates hepatic insulin resistance by enhancing mitochondrial architecture via the SIRT1/Opa1 signalling pathway	6
ARG1 functions as a tumor suppressor in breast cancer	6
Changes in the mammary gland during aging and its links with breast diseases	6
Quercetin induces autophagy-associated death in HL-60 cells through CaMKKβ/AMPK/mTOR signal pathway	6
Phage display: an ideal platform for coupling protein to nucleic acid	6
Telocytes reduce oxidative stress by downregulating DUOX2 expression in inflamed lungs of mice	6
RETREG1-mediated ER-phagy activation induced by glucose deprivation alleviates nucleus pulposus cell damage via ER stress pathway	6
The binding epitope of sintilimab on PD-1 revealed by AbMap	6
The essential function of IL-33 in metabolic regulation	6
Abemaciclib induces apoptosis in cardiomyocytes by activating the Hippo signaling pathway	6
miR-487a performs oncogenic functions in osteosarcoma by targeting mRNA	6
DSCR9/miR-21-5p axis inhibits pancreatic cancer proliferation and resistance to gemcitabine via BTG2 signaling	6
Glutamine deprivation induces ferroptosis in pancreatic cancer cells	6
The origin of unwanted editing byproducts in gene editing	6
Dexmedetomidine maintains blood–brain barrier integrity by inhibiting Drp1-related endothelial mitochondrial dysfunction in ischemic stroke	6
miR-378c suppresses Wilms tumor development via negatively regulating CAMKK2	6
STAT3 and AKT signaling pathways mediate oncogenic role of NRSF in hepatocellular carcinoma	6
Urothelial cancer associated 1 (UCA1) regulates trophoblast viability, proliferation, and migration via modulating the UCA1/miR-455/RUNX2 signaling pathway	6
Neuroprotective effects of ProBeptigen/CMI-168 on aging-induced cognitive decline and neuroinflammation in mice: a comparison with essence of chicken	6
Blockade of T helper 17 cell function ameliorates recurrent <italic>Clostridioides difficile</italic> infection in mice	6