Neural Regeneration Research

Article	Citations
Generating oligodendroglia from adult mesenchymal cells for transplantation: cell reprogramming or direct lineage conversion?	228
Increased retinal venule diameter as a prognostic indicator for recurrent cerebrovascular events: a prospective observational study	162
Multiple factors to assist human-derived induced pluripotent stem cells to efficiently differentiate into midbrain dopaminergic neurons	119
Phosphorylation-driven aggregative proteins in neurodegenerative diseases: implications and therapeutics	108
The circ_0002538/miR-138-5p/plasmolipin axis regulates Schwann cell migration and myelination in diabetic peripheral neuropathy	98
SCFD1 in amyotrophic lateral sclerosis: reconciling a genetic association with in vivo functional analysis	93
Dual-targeting AAV9P1-mediated neuronal reprogramming in a mouse model of traumatic brain injury	90
Functions of nuclear factor Y in nervous system development, function and health	87
Rbm8a regulates neurogenesis and reduces Alzheimer’s disease-associated pathology in the dentate gyrus of 5×FAD mice	76
Exercise-with-melatonin therapy improves sleep disorder and motor dysfunction in a rat model of ischemic stroke	75
Prolonged intermittent theta burst stimulation restores the balance between A2AR- and A1R-mediated adenosine signaling in the 6-hydroxidopamine model of Parkinson’s disease	73
Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axis	71
Protocadherin gamma C3: a new player in regulating vascular barrier function	71
Could inorganic polyphosphate be a valid target against neuronal senescence?	68
Neuromodulation techniques for modulating cognitive function: Enhancing stimulation precision and intervention effects	66
Tropism-shifted AAV-PHP.eB-mediated bFGF gene therapy promotes varied neurorestoration after ischemic stroke in mice	63
Rapamycin as a preventive intervention for Alzheimer’s disease in APOE4 carriers: Targeting brain metabolic and vascular restoration	62
Beyond apoptosis: Implications of annexin-V binding to myeloid cells in DARC (Detection of Apoptosing Retinal Cells) imaging	61
Delayed microglial depletion protects against white matter injury following neonatal cerebral hemorrhage in mice	60
Telomere length as a predictive marker for long-term cognitive function in a mouse model of subarachnoid hemorrhage	59
Intriguing role of the Golgi apparatus in astrocyte function: Implications for disorders	57
The intrinsic excitability of and autophagy protein expression levels in dentate gyrus ensembles regulate fear generalization	57
FKBP51: A new target for Parkinson’s disease	57
Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy	57
Stepping up after spinal cord injury: negotiating an obstacle during walking	56

Activity-dependent regulation of cortical cell numbers: Role of neuronal activity in cortical circuit formation	53
Enhancement of lysosome biogenesis as a potential therapeutic approach for neurodegenerative diseases	53
Krüppel-like factor 2 (KLF2), a potential target for neuroregeneration	52
Metformin promotes angiogenesis and functional recovery in aged mice after spinal cord injury by adenosine monophosphate-activated protein kinase/endothelial nitric oxide synthase pathway	52
Potential common pathogenesis of several neurodegenerative diseases	52
Human endogenous retrovirus type-W and multiple sclerosis–related smoldering neuroinflammation	51
Role of copper chelating agents: between old applications and new perspectives in neuroscience	51
LL-37 and CsgC exemplify the crosstalk between anti-amyloid, antimicrobial, and anti-biofilm protein activities	51
Neuroserpin alleviates cerebral ischemia-reperfusion injury by suppressing ischemia-induced endoplasmic reticulum stress	50
Liposomes as versatile agents for the management of traumatic and nontraumatic central nervous system disorders: drug stability, targeting efficiency, and safety	50
Role of the globus pallidus in motor and non-motor symptoms of Parkinson’s disease	49
NECAB family of neuronal calcium-binding proteins in health and disease	49
Neuropsychiatric symptoms and apolipoprotein E genotypes in neurocognitive disorders	49
The complex roles of m6A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases	48
Neurogenesis dynamics in the olfactory bulb: deciphering circuitry organization, function, and adaptive plasticity	48
Ethanol changes Nestin-promoter induced neural stem cells to disturb newborn dendritic spine remodeling in the hippocampus of mice	48
Selective deletion of zinc transporter 3 in amacrine cells promotes retinal ganglion cell survival and optic nerve regeneration after injury	47
Injectable collagen scaffold with human umbilical cord-derived mesenchymal stem cells promotes functional recovery in patients with spontaneous intracerebral hemorrhage: phase I clinical trial	47
Autolysosomal acidification impairment as a mediator for TNFR1 induced neuronal necroptosis in Alzheimer's disease	47
Eph receptor A4 regulates motor neuron ferroptosis in spinal cord ischemia/reperfusion injury in rats	46
Astrocyte chloride, excitatory-inhibitory balance and epilepsy	46
Mesenchymal stem cell-derived extracellular vesicles therapy in traumatic central nervous system diseases: a systematic review and meta-analysis	46
Small extracellular vesicles secreted by induced pluripotent stem cell-derived mesenchymal stem cells improve postoperative cognitive dysfunction in mice with diabetes	46
Chx10+V2a interneurons in spinal motor regulation and spinal cord injury	46
Peripheral mitochondrial DNA as a neuroinflammatory biomarker for major depressive disorder	46
Clemastine in remyelination and protection of neurons and skeletal muscle after spinal cord injury	46
Amyloid-beta and tau protein beyond Alzheimer’s disease	45
Mitochondrial transplantation: a promising strategy for the treatment of retinal degenerative diseases	45
Targeting tau in Alzheimer's disease: from mechanisms to clinical therapy	45
Mitochondrial dynamics dysfunction and neurodevelopmental disorders: From pathological mechanisms to clinical translation	44
Glycine decarboxylase as a novel regulator of N-methyl-D-aspartate receptor function: Implications for pathophysiology of schizophrenia	43
Synaptopathy in CHMP2B frontotemporal dementia highlights the synaptic vesicle cycle as a therapeutic target	43
Functional near-infrared spectroscopy in non-invasive neuromodulation	41
Decoding molecular mechanisms: brain aging and Alzheimer’s disease	41
Endorepellin downregulation promotes angiogenesis after experimental traumatic brain injury	40
Amyotrophic lateral sclerosis disease burden: doing better at getting better	40
Premature axon-oligodendrocyte interaction contributes to stalling of experimental axon regeneration after injury to the white matter	39
Regulatory role of neuronal guidance proteins in spinal cord injury	39
Dynamic regulation of the developmental establishment of the adult hippocampal neural stem cell pool	39
Role of calcium homeostasis in retinal ganglion cell degeneration	38
Interferon regulatory factor 1 enhances T cell differentiation in patients with myasthenia gravis	38
Argatroban promotes recovery of spinal cord injury by inhibiting the PAR1/JAK2/STAT3 signaling pathway	38
The roles of microglia and astrocytes in inflammasomes and neurological disorders	38
Amyloid degradation mechanisms and potential synergistic effects	37
Utility of droplet digital polymerase chain reaction for studying somatic mosaicism: brain malformations and beyond	37
Cerebral organoids as a platform to model prenatal exposure to drugs of abuse	37
Treatment with β-sitosterol ameliorates the effects of cerebral ischemia/reperfusion injury by suppressing cholesterol overload, endoplasmic reticulum stress, and apoptosis	37
Advances and unmet needs in fluid and tissue biomarkers in Parkinson’s disease	37
Post-acute ischemic stroke hyperglycemia aggravates destruction of the blood-brain barrier	37
Blocking postsynaptic density-93 binding to C-X3-C motif chemokine ligand 1 promotes microglial phenotypic transformation during acute ischemic stroke	37

Insights from an academic endeavor into central nervous system drug discovery	36
Advances in non-invasive imaging of proteinopathies in animal models of neurodegenerative diseases	36
Targeting muscle to treat Charcot-Marie-Tooth disease	36
New insights on the role of chondroitin sulfate proteoglycans in neural stem cell–mediated repair in spinal cord injury	36
Prospect in Alzheimer’s disease integrative therapy targeting both amyloid-beta and tau	36
On the functions of astrocyte-mediated neuronal slow inward currents	36
Modulation of p75 neurotrophin receptor mitigates brain damage following ischemic stroke in mice	36
Therapeutic effects of low-intensity transcranial focused ultrasound stimulation on ischemic stroke in rats: An in vivo evaluation using electrical impedance tomography	35
NLRP3/1-mediated pyroptosis: beneficial clues for the development of novel therapies for Alzheimer’s disease	35
New aspects of a small GTPase RAB35 in brain development and function	35
Unraveling the role of ufmylation in the brain	35
Exercise training promotes nerve cell repair and regeneration after spinal cord injury	35
Prediction of cell-cell communication patterns of dorsal root ganglion cells: single-cell RNA sequencing data analysis	35
A core scientific problem in the treatment of central nervous system diseases: newborn neurons	35
Converging assemblies: A putative building block for brain function and for interfacing with the brain	35
Neurodegeneration-induced angioarchitecture remodeling	34
Pharmacological interventions targeting the microcirculation following traumatic spinal cord injury	34
The neuroprotective effects of oxygen therapy in Alzheimer’s disease: a narrative review	34
The secondary injury cascade after spinal cord injury: an analysis of local cytokine/chemokine regulation	34
Application of artificial intelligence for the prediction of amyloidoses	34
Multimodal MRI combined with RNA sequencing reveals pathological signatures in the 9-month-old 3×Tg-AD mouse brain	34
Bidirectional communication between the gut microbiota and the central nervous system	34
Delta-opioid receptor–mediated neural protection and regeneration	34
Exacerbation of neuronal senescence after spinal cord injury: Role of the macrophage-derived transforming growth factor-β1–SMAD2 signaling axis	34
Treating dysfunctional one-carbon metabolism in glaucoma	34
Artificial intelligence and peripheral neuropathies: Strategies for the development, application, and repair of regenerative biomaterials	33
New insights into the role of the endoplasmic reticulum in microglia	33
Retraction: Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children	33
Targeting sigma receptors for Alzheimer’s disease treatment	33
Sex modulates the outcome of subthalamic nucleus deep brain stimulation in patients with Parkinson’s disease	32
Microglia depletion as a therapeutic strategy: friend or foe in multiple sclerosis models?	32
Functions and mechanisms of cytosolic phospholipase A2 in central nervous system trauma	32
Modulation of the excitation/inhibition balance by astrocytes in a tripartite synapse model of Alzheimer's disease	32
Commentary on “PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons”	32
M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats	32
Neurodevelopmental defects as a primer of neurodegeneration: lessons from spinal muscular atrophy and Huntington’s disease	32
Biochanin A attenuates spinal cord injury in rats during early stages by inhibiting oxidative stress and inflammasome activation	32
Small extracellular vesicles derived from cerebral endothelial cells with elevated microRNA 27a promote ischemic stroke recovery	32
Erythropoietin inhibits ferroptosis and ameliorates neurological function after spinal cord injury	31
Inducing prion protein shedding as a neuroprotective and regenerative approach in pathological conditions of the brain: from theory to facts	31
Extracellular vesicles: multiple signaling capabilities and translation into promising therapeutic targets to promote neuronal plasticity	31
A review of the neurotransmitter system associated with cognitive function of the cerebellum in Parkinson’s disease	31
Newfound physiological function of FAIM protein offers hope of novel disease-modifying therapy for Alzheimer’s disease	31
Effects of C2 hemisection on respiratory and cardiovascular functions in rats	31
Exploration of C-terminal CX3CL1 for reducing age-dependent neurodegeneration	31
Neuroprotection provided by polyphenols and flavonoids in photoreceptor degenerative diseases	31
Exploring the novel role of oligodendrocyte precursor cells in phagocytosis: beyond myelinogenesis	30
Imaging mass spectrometry: a molecular microscope for studying the role of lipids in Parkinson’s disease	30
Dysfunction of synaptic endocytic trafficking in Parkinson’s disease	30
Intranasal therapies for neonatal hypoxic-ischemic encephalopathy	30
Utilizing engineered extracellular vesicles as delivery vectors in the management of ischemic stroke: a special outlook on mitochondrial delivery	30
Neuronal chemokines: new insights into neuronal communication after injury	30
Tau’s function and dysfunction in the brain	30
The effects and potential of microglial polarization and crosstalk with other cells of the central nervous system in the treatment of Alzheimer’s disease	30
Crosstalk among canonical Wnt and Hippo pathway members in skeletal muscle and at the neuromuscular junction	30
Data and subject heterogeneity and data sharing: keys to translational success in spinal cord injury research?	30
Two become one: combination of two risk factors in a new glaucoma animal model	30
Bioactive material promotes long-distance regeneration of optic nerve to restore visual functions	30
Effects of quercetin and its derivatives in in vivo models of neuroinflammation: A systematic review and meta-analysis	29
Neural and Müller glial adaptation of the retina to photoreceptor degeneration	29
Secretase inhibition in Alzheimer’s disease therapeutics reveals functional roles of amyloid-beta42	29
Potential role of cytosolic PTEN-induced kinase 1 in facilitating proteaphagy	29
Knockout of Sirt2 alleviates traumatic brain injury in mice	29
Clues from a missense mutation of the adenosine A1 receptor gene associated with early-onset Parkinson’s disease	29
Blood-brain barrier pathology in cerebral small vessel disease	29
Stiffness-tunable biomaterials provide a good extracellular matrix environment for axon growth and regeneration	29
Schwann cell extracellular vesicles: judging a book by its cover	29
Post-transcriptional mechanisms controlling neurogenesis and direct neuronal reprogramming	29
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis	29
Microglial depletion impairs glial scar formation and aggravates inflammation partly by inhibiting STAT3 phosphorylation in astrocytes after spinal cord injury	29
5-Hydroxytryptamine: a potential therapeutic target in amyotrophic lateral sclerosis	28
Adipocytes and macrophages after stroke: Interactions between metabolism and immunity	28
Interconnections between diabetic corneal neuropathy and diabetic retinopathy: diagnostic and therapeutic implications	28
Carboplatin restores neuronal toxicity in FUS-linked amyotrophic lateral sclerosis	28
Artificial nerve graft constructed by coculture of activated Schwann cells and human hair keratin for repair of peripheral nerve defects	28
Implication of gut microbiome in age-related macular degeneration	28
Anti-vascular endothelial growth factor drugs combined with laser photocoagulation maintain retinal ganglion cell integrity in patients with diabetic macular edema: study protocol for a prospective, n	28
The critical role of the endolysosomal system in cerebral ischemia	28
Making bridges between preclinical and clinical insights into age-related cognitive decline	28
Contribution of glial cells to the neuroprotective effects triggered by repetitive magnetic stimulation	28

Adipose mesenchymal stem cell-derived extracellular vesicles reduce glutamate-induced excitotoxicity in the retina	28
Mechanosensitive Piezo1 channel regulation of microglial cell function and implications to neurodegenerative diseases and neuroinflammation	28
Biomaterial-based strategies: a new era in spinal cord injury treatment	28
Insights into the transcriptomic heterogeneity of brain endothelial cells in normal aging and Alzheimer’s disease	28
Letter from the Editor-in-Chief	27
Neuronal autosis: the self-destructive side of autophagy involved in hypoxic-ischemic neuronal death	27
Targeting the dopaminergic midbrain in Alzheimer’s disease: Therapeutic potential of focusing on specific neural circuits rather than single molecular pathways	27
Emerging roles of astrocytes in blood-brain barrier disruption upon amyloid-beta insults in Alzheimer’s disease	27
Transcranial photobiomodulation for the brain: a wide range of clinical applications	27
Basic fibroblast growth factor sustained-release system promotes neurogenesis and tissue repair after spinal cord injury	27
Genetic and pathway complexity in Alzheimer’s disease: Insights from multi-omic data about the immune response and mitochondrial function	27
Low-intensity transcranial ultrasound neuromodulation promotes neuronal regeneration: A new hope for noninvasive treatment of neurodegenerative diseases	27
Heterogeneity of mature oligodendrocytes in the central nervous system	27
Magnesium-L-threonate treats Alzheimer’s disease by modulating the microbiota-gut-brain axis	27
Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles	27
Multiple sclerosis drug repurposing for neuroregeneration	27
Metformin remodels the myelin landscape	27
High-dose biotin neither fosters remyelination nor stimulates malonyl coenzyme A synthesis in the regenerating nerve	26
Taurine: a promising nutraceutic in the prevention of retinal degeneration	26
Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion	26
In vivo measures of glutamate and the excitation/inhibition imbalance in brain disorders	26
Targeting autophagy by polyphenols to prevent glycative stress-toxicity in the brain	26
Retinal glial cells in glaucoma and age-related retinal diseases: Inflammatory responses, disease transitions, and translational perspectives	26
Synaptic pathology in multiple sclerosis: a role for Nogo-A signaling in astrocytes?	26
Oxidative stress in retinal pigment epithelium degeneration: from pathogenesis to therapeutic targets in dry age-related macular degeneration	26
Pathophysiological changes of muscle after ischemic stroke: a secondary consequence of stroke injury	26
Brain injury after subarachnoid hemorrhage: Glymphatic contributions	26
Targeting interleukin-6 trans-signaling to improve post-stroke inflammation: A precision immunotherapy perspective	25
Restarting synaptic remodeling and structural network: New treatment strategies for epilepsy	25
Transcriptomic and morphological characterization reveals distinct regeneration kinetics in immediate versus delayed nerve repair	25
Alpha-synuclein-induced upregulation of SKI family transcriptional corepressor 1: A new player in aging and Parkinson’s disease?	25
Protein disulfide isomerases in amyotrophic lateral sclerosis: Endoplasmic reticulum proteostasis and neuromuscular function	25
Blood-based biomarkers and early diagnosis of Alzheimer’s disease	25
Integrated multi-omics and machine learning identify Casp8 and Pycard as central regulators of pyroptosis and necroptosis in spinal cord injury	25
Iron-handling solute carrier SLC22A17 as a blood–brain barrier target after stroke	25
Analysis of the dual role of amyloid-beta in Alzheimer’s disease through multi-omics integration	25
Astrocyte evolution and human specificity	25
Electroactive hydrogel with human umbilical cord mesenchymal stem cell–derived exosomes remodels the microenvironment of spinal cord lesion sites and rebuilds neural circuits after injury	25
Secretory autophagy in neurons: More than throwing out the trash?	24
Molecular mechanisms after optic nerve injury: Neurorepair strategies from a transcriptomic perspective	24
Neuroinflammation revisited through the microglial lens	24
Persistent alterations in gray matter in COVID-19 patients experiencing sleep disturbances: a 3-month longitudinal study	24
Transplantation of human neural stem cells repairs neural circuits and restores neurological function in the stroke-injured brain	24
MET receptor tyrosine kinase promotes the generation of functional synapses in adult cortical circuits	24
Exosomes in stroke management: A promising paradigm shift in stroke therapy	24
Proteostasis decline and endoplasmic reticulum stress in aging: Implications for cellular senescence and senescence-associated secretory phenotype regulation	24
Detection of white matter microstructural changes in patients with systemic lupus erythematosus based on multiple diffusion models and related diffusion metrics	24
Low-density lipoprotein receptor–related protein 1 mediates α-synuclein transmission from the striatum to the substantia nigra in animal models of Parkinson’s disease	24
MAPT-isoform 0N3R is essential for human brain development: Loss-of-function for novel TAU-associated disease paradigms	24
Rethinking microglia from a circadian perspective in neuroimmunology: New insights	24
C–C motif chemokine ligand 2/C–C motif chemokine receptor 2 pathway as a therapeutic target and regulatory mechanism for spinal cord injury	24
Extracellular vesicles for neural regeneration after spinal cord injury	23
Fibrinogen’s potential role in connecting cerebrovascular abnormalities with glymphatic dysfunction in Alzheimer’s disease	23
Establishing a role of the insulin receptor in microglia	23
Stable isotope labeling-mass spectrometry as a new approach to determine remyelination	23
Rebuilding insight into the pathophysiology of Alzheimer's disease through new blood-brain barrier models	23
Inflammation and retinal degenerative diseases	23
PANoptosis: new insights in regulated cell death in ischemia/reperfusion models	23
Mitochondrial therapeutics and mitochondrial transfer for neurodegenerative diseases and aging	23
Antisense oligonucleotides provide optimism to the therapeutic landscape for tauopathies	23
Ferroptosis mechanism and Alzheimer's disease	23
Sex differences in Alzheimer’s disease: an urgent research venue to follow	23
Renin-angiotensin system in the central nervous system: focus on Huntington’s disease	23
Gut microbiota dysbiosis contributes to α-synuclein-related pathology associated with C/EBPβ/AEP signaling activation in a mouse model of Parkinson's disease	23
Retraction: Resveratrol inhibits matrix metalloproteinases to attenuate neuronal damage in cerebral ischemia: a molecular docking study exploring possible neuroprotection	23
Multifaceted superoxide dismutase 1 expression in amyotrophic lateral sclerosis patients: a rare occurrence?	23
Brain-penetrating neurotrophic factor mimetics: HER-096 as a disease-modifying therapy for Parkinson’s disease	23
Actin(g) toward a revised understanding of the role of cytoskeletal dynamics in neuronal bioenergetics	23
Brain and spinal cord trauma: what we know about the therapeutic potential of insulin growth factor 1 gene therapy	23
Intranasal nerve growth factor for prevention and recovery of the outcomes of traumatic brain injury	23
Combined cell-based therapy strategies for the treatment of Parkinson’s disease: focus on mesenchymal stromal cells	23
Striatum-specific mechanisms regulate neuronal cell cycle re-entry: the choice between life and death	23
Blockade of Rho-associated kinase prevents inhibition of axon regeneration of peripheral nerves induced by anti-ganglioside antibodies	22
cGAS–STING pathway modulation: A new hope for neural regeneration	22
Unexpected role of complement component 8 gamma chain in the inflamed brain	22
MicroRNA and Alzheimer’s disease: Diagnostic biomarkers and potential therapeutic targets	22
Correlation between the gut microbiome and neurodegenerative diseases: a review of metagenomics evidence	22
Magnetic resonance imaging focused on the ferritin heavy chain 1 reporter gene detects neuronal differentiation in stem cells	22
Beyond wrecking a wall: revisiting the concept of blood–brain barrier breakdown in ischemic stroke	22
Grafts of hydrogel-embedded electrically stimulated subventricular stem cells into the stroke cavity improves functional recovery of mice	22
Targeting the NLRP3–NEK7 axis with rebamipide: Drug repurposing in Parkinson’s disease	22
Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion	22
Remaking a connection: molecular players involved in post-injury synapse formation	22
Neuronal plasticity and its role in Alzheimer’s disease and Parkinson’s disease	22
Brain organoids and genome editing: A new era in understanding human brain development and disorders	22
Exploring the synergy of the eye-brain connection: neuromodulation approaches for neurodegenerative disorders through transcorneal electrical stimulation	22
Cholinergic pathways in neural stem cell regulation and glioblastoma progression: Shared origins and mechanisms	21
Clinical associations of corneal neuromas with ocular surface diseases	21
Could mammalian inorganic polyphosphate be a crucial signaling molecule in neurological disorders?	21
Combination of novel RNA sequencing and sophisticated network modeling to reveal a common denominator in amyotrophic lateral sclerosis?	21
Mechanisms underlying neuroimmune networks as central regulators in combating neurodegenerative diseases	21
Techniques and factors for reducing chronic neuropathic pain: A review	21
The transient receptor potential melastatin 2: a new therapeutical target for Parkinson′s disease?	21
Nuance of inward rectifying potassium (Kir) channel dysfunctions in neurodegenerative diseases	21
Deconvolution in Alzheimer’s disease	21