Neural Regeneration Research

Papers
(The TQCC of Neural Regeneration Research is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)
ArticleCitations
Generating oligodendroglia from adult mesenchymal cells for transplantation: cell reprogramming or direct lineage conversion?375
Chronic traumatic encephalopathy: genes load the gun and repeated concussion pulls the trigger313
Contribution of adult-born neurons to memory consolidation during rapid eye movement sleep221
Functions of nuclear factor Y in nervous system development, function and health176
Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axis138
Metformin promotes angiogenesis and functional recovery in aged mice after spinal cord injury by adenosine monophosphate-activated protein kinase/endothelial nitric oxide synthase pathway116
Protocadherin gamma C3: a new player in regulating vascular barrier function112
FKBP51: A new target for Parkinson’s disease101
Retraction: Emerging concepts underlying selective neuromuscular dysfunction in infantile-onset spinal muscular atrophy96
Mitochondrial transplantation: a promising strategy for the treatment of retinal degenerative diseases79
SCFD1 in amyotrophic lateral sclerosis: reconciling a genetic association with in vivo functional analysis77
LL-37 and CsgC exemplify the crosstalk between anti-amyloid, antimicrobial, and anti-biofilm protein activities76
Glymphatic imaging and modulation of the optic nerve73
Synaptopathy in CHMP2B frontotemporal dementia highlights the synaptic vesicle cycle as a therapeutic target68
Could inorganic polyphosphate be a valid target against neuronal senescence?68
Activity-dependent regulation of cortical cell numbers: Role of neuronal activity in cortical circuit formation67
Beyond apoptosis: Implications of annexin-V binding to myeloid cells in DARC (Detection of Apoptosing Retinal Cells) imaging66
Krüppel-like factor 2 (KLF2), a potential target for neuroregeneration63
Facial reanimation with interposition nerve graft or masseter nerve transfer: a comparative retrospective study62
Mechanosensitivity of N-methyl-D-aspartate receptors (NMDAR) is the key through which amyloid beta oligomers activate them61
Increased retinal venule diameter as a prognostic indicator for recurrent cerebrovascular events: a prospective observational study60
Neurogenesis dynamics in the olfactory bulb: deciphering circuitry organization, function, and adaptive plasticity59
Human endogenous retrovirus type-W and multiple sclerosis–related smoldering neuroinflammation59
Necrostatin-1 decreases necroptosis and inflammatory markers after intraventricular hemorrhage in mice58
The power of “touch” and early enriched stimulation: neuroplasticity effects in rodents and preterm infants57
Neuromodulation techniques for modulating cognitive function: Enhancing stimulation precision and intervention effects56
Prolonged intermittent theta burst stimulation restores the balance between A2AR- and A1R-mediated adenosine signaling in the 6-hydroxidopamine model of Parkinson’s disease55
The intrinsic excitability of and autophagy protein expression levels in dentate gyrus ensembles regulate fear generalization55
Telomere length as a predictive marker for long-term cognitive function in a mouse model of subarachnoid hemorrhage55
Dual-targeting AAV9P1-mediated neuronal reprogramming in a mouse model of traumatic brain injury54
Transcription factors promote neural regeneration after spinal cord injury53
Small extracellular vesicles secreted by induced pluripotent stem cell-derived mesenchymal stem cells improve postoperative cognitive dysfunction in mice with diabetes51
Stepping up after spinal cord injury: negotiating an obstacle during walking51
Mitochondrial dynamics dysfunction and neurodevelopmental disorders: From pathological mechanisms to clinical translation51
Rapamycin as a preventive intervention for Alzheimer’s disease in APOE4 carriers: Targeting brain metabolic and vascular restoration51
Downregulation of miR-491-5p promotes neovascularization after traumatic brain injury50
Therapeutic potential of glial cell line-derived neurotrophic factor and cell reprogramming for hippocampal-related neurological disorders48
Role of the globus pallidus in motor and non-motor symptoms of Parkinson’s disease48
Peripheral mitochondrial DNA as a neuroinflammatory biomarker for major depressive disorder48
The complex roles of m6A modifications in neural stem cell proliferation, differentiation, and self-renewal and implications for memory and neurodegenerative diseases48
Astrocyte chloride, excitatory-inhibitory balance and epilepsy48
Tropism-shifted AAV-PHP.eB-mediated bFGF gene therapy promotes varied neurorestoration after ischemic stroke in mice47
Bradykinin postconditioning protects rat hippocampal neurons after restoration of spontaneous circulation following cardiac arrest via activation of the AMPK/mTOR signaling pathway47
GDNF to the rescue: GDNF delivery effects on motor neurons and nerves, and muscle re-innervation after peripheral nerve injuries46
Axonal protein synthesis in central nervous system regeneration: is building an axon a local matter?46
Chx10+V2a interneurons in spinal motor regulation and spinal cord injury46
Enhancement of lysosome biogenesis as a potential therapeutic approach for neurodegenerative diseases46
Selective deletion of zinc transporter 3 in amacrine cells promotes retinal ganglion cell survival and optic nerve regeneration after injury46
NECAB family of neuronal calcium-binding proteins in health and disease46
The delivery of miR-21a-5p by extracellular vesicles induces microglial polarization via the STAT3 pathway following hypoxia-ischemia in neonatal mice45
Multiple factors to assist human-derived induced pluripotent stem cells to efficiently differentiate into midbrain dopaminergic neurons45
Neuroserpin alleviates cerebral ischemia-reperfusion injury by suppressing ischemia-induced endoplasmic reticulum stress45
Eph receptor A4 regulates motor neuron ferroptosis in spinal cord ischemia/reperfusion injury in rats45
Ethanol changes Nestin-promoter induced neural stem cells to disturb newborn dendritic spine remodeling in the hippocampus of mice44
Role of copper chelating agents: between old applications and new perspectives in neuroscience44
Functional near-infrared spectroscopy in non-invasive neuromodulation44
Activation of medial septum cholinergic neurons restores cognitive function in temporal lobe epilepsy43
Phosphorylation-driven aggregative proteins in neurodegenerative diseases: implications and therapeutics43
Rbm8a regulates neurogenesis and reduces Alzheimer’s disease-associated pathology in the dentate gyrus of 5×FAD mice43
Clemastine in remyelination and protection of neurons and skeletal muscle after spinal cord injury42
Potential common pathogenesis of several neurodegenerative diseases42
Amyloid-beta and tau protein beyond Alzheimer’s disease42
Increased activation of the caudate nucleus and parahippocampal gyrus in Parkinson’s disease patients with dysphagia after repetitive transcranial magnetic stimulation: a case-control study42
Rapid GFAP and Iba1 expression changes in the female rat brain following spinal cord injury42
Exercise-with-melatonin therapy improves sleep disorder and motor dysfunction in a rat model of ischemic stroke42
Glycine decarboxylase as a novel regulator of N-methyl-D-aspartate receptor function: Implications for pathophysiology of schizophrenia42
Decoding molecular mechanisms: brain aging and Alzheimer’s disease41
Phosphorylated tau as a toxic agent in synaptic mitochondria: implications in aging and Alzheimer’s disease41
Liposomes as versatile agents for the management of traumatic and nontraumatic central nervous system disorders: drug stability, targeting efficiency, and safety41
Involvement of glucose transporter overexpression in the protection or damage after ischemic stroke40
Exosomes derived from bone marrow mesenchymal stem cells protect the injured spinal cord by inhibiting pericyte pyroptosis40
The circ_0002538/miR-138-5p/plasmolipin axis regulates Schwann cell migration and myelination in diabetic peripheral neuropathy39
Targeting tau in Alzheimer's disease: from mechanisms to clinical therapy39
Mesenchymal stem cell-derived extracellular vesicles therapy in traumatic central nervous system diseases: a systematic review and meta-analysis39
Autolysosomal acidification impairment as a mediator for TNFR1 induced neuronal necroptosis in Alzheimer's disease39
The role of miRNA in retinal ganglion cell health and disease39
Neuropsychiatric symptoms and apolipoprotein E genotypes in neurocognitive disorders39
Insights from an academic endeavor into central nervous system drug discovery38
Delayed microglial depletion protects against white matter injury following neonatal cerebral hemorrhage in mice38
Amyotrophic lateral sclerosis disease burden: doing better at getting better37
Utility of droplet digital polymerase chain reaction for studying somatic mosaicism: brain malformations and beyond37
Exploration of C-terminal CX3CL1 for reducing age-dependent neurodegeneration37
New aspects of a small GTPase RAB35 in brain development and function37
Endorepellin downregulation promotes angiogenesis after experimental traumatic brain injury37
Brain ischemia as a bridge to Alzheimer’s disease37
Retraction: Ultrasound guided neural stem cell transplantation through the lateral ventricle for treatment of cerebral palsy in children36
Premature axon-oligodendrocyte interaction contributes to stalling of experimental axon regeneration after injury to the white matter36
Modulation of p75 neurotrophin receptor mitigates brain damage following ischemic stroke in mice36
Newfound physiological function of FAIM protein offers hope of novel disease-modifying therapy for Alzheimer’s disease36
Unraveling the role of ufmylation in the brain35
Targeting muscle to treat Charcot-Marie-Tooth disease35
Ki20227 aggravates apoptosis, inflammatory response, and oxidative stress after focal cerebral ischemia injury35
Advances in non-invasive imaging of proteinopathies in animal models of neurodegenerative diseases35
Bidirectional communication between the gut microbiota and the central nervous system34
Optogenetics stimulates nerve reorganization in the contralesional anterolateral primary motor cortex in a mouse model of ischemic stroke34
Extracellular vesicles: multiple signaling capabilities and translation into promising therapeutic targets to promote neuronal plasticity34
Exercise training promotes nerve cell repair and regeneration after spinal cord injury34
Designing nanocarriers to overcome the limitations in conventional drug administration for Parkinson’s disease33
On the functions of astrocyte-mediated neuronal slow inward currents33
A core scientific problem in the treatment of central nervous system diseases: newborn neurons33
Dynamic regulation of the developmental establishment of the adult hippocampal neural stem cell pool33
New insights into the role of the endoplasmic reticulum in microglia33
Converging assemblies: A putative building block for brain function and for interfacing with the brain33
Neuronal and endothelial transglutaminase-2 expression in experimental autoimmune encephalomyelitis and multiple sclerosis33
Multimodal MRI combined with RNA sequencing reveals pathological signatures in the 9-month-old 3×Tg-AD mouse brain32
Commentary on “PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons”32
Delta-opioid receptor–mediated neural protection and regeneration32
Therapeutic effects of low-intensity transcranial focused ultrasound stimulation on ischemic stroke in rats: An in vivo evaluation using electrical impedance tomography32
Artificial intelligence and peripheral neuropathies: Strategies for the development, application, and repair of regenerative biomaterials32
Sex modulates the outcome of subthalamic nucleus deep brain stimulation in patients with Parkinson’s disease32
Effects of C2 hemisection on respiratory and cardiovascular functions in rats32
Growth differentiation factor 5: a neurotrophic factor with neuroprotective potential in Parkinson’s disease31
Status of precision medicine approaches to traumatic brain injury31
Amyloid degradation mechanisms and potential synergistic effects31
Exacerbation of neuronal senescence after spinal cord injury: Role of the macrophage-derived transforming growth factor-β1-SMAD2 signaling axis31
Neurodevelopmental defects as a primer of neurodegeneration: lessons from spinal muscular atrophy and Huntington's disease31
Blocking postsynaptic density-93 binding to C-X3-C motif chemokine ligand 1 promotes microglial phenotypic transformation during acute ischemic stroke31
Regulatory role of neuronal guidance proteins in spinal cord injury31
Role of calcium homeostasis in retinal ganglion cell degeneration31
Application of artificial intelligence for the prediction of amyloidoses31
NOVA1 promotes SMN2 exon 7 splicing by binding the UCAC motif and increases SMN protein expression31
Ruxolitinib attenuates secondary injury after traumatic spinal cord injury31
Argatroban promotes recovery of spinal cord injury by inhibiting the PAR1/JAK2/STAT3 signaling pathway31
NLRP3/1-mediated pyroptosis: beneficial clues for the development of novel therapies for Alzheimer’s disease30
Neuroprotection provided by polyphenols and flavonoids in photoreceptor degenerative diseases30
Homer signaling pathways as effective therapeutic targets for ischemic and traumatic brain injuries and retinal lesions30
Microglia depletion as a therapeutic strategy: friend or foe in multiple sclerosis models?30
A Drosophila perspective on retina functions and dysfunctions30
Functions and mechanisms of cytosolic phospholipase A2 in central nervous system trauma30
M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats30
Cell senescence, loss of splicing, and lipid metabolism in TDP-43-related neurodegenerative processes30
Utilizing engineered extracellular vesicles as delivery vectors in the management of ischemic stroke: a special outlook on mitochondrial delivery30
Interferon regulatory factor 1 enhances T cell differentiation in patients with myasthenia gravis30
Erythropoietin inhibits ferroptosis and ameliorates neurological function after spinal cord injury30
Optical tissue clearing enables rapid, precise and comprehensive assessment of three-dimensional morphology in experimental nerve regeneration research29
A review of the neurotransmitter system associated with cognitive function of the cerebellum in Parkinson’s disease29
microRNA-455-5p alleviates neuroinflammation in cerebral ischemia/reperfusion injury29
Treatment with β-sitosterol ameliorates the effects of cerebral ischemia/reperfusion injury by suppressing cholesterol overload, endoplasmic reticulum stress, and apoptosis29
Prediction of cell-cell communication patterns of dorsal root ganglion cells: single-cell RNA sequencing data analysis29
Crosstalk among canonical Wnt and Hippo pathway members in skeletal muscle and at the neuromuscular junction29
Effects of electroacupuncture on the functionality of NG2-expressing cells in perilesional brain tissue of mice following ischemic stroke29
Exploring the novel role of oligodendrocyte precursor cells in phagocytosis: beyond myelinogenesis29
Pharmacological interventions targeting the microcirculation following traumatic spinal cord injury29
Exendin-4 and linagliptin attenuate neuroinflammation in a mouse model of Parkinson′s disease29
Biochanin A attenuates spinal cord injury in rats during early stages by inhibiting oxidative stress and inflammasome activation29
Neuron-fibrous scaffold interfaces in the peripheral nervous system: a perspective on the structural requirements29
The neuroprotective effects of oxygen therapy in Alzheimer’s disease: a narrative review29
New insights on the role of chondroitin sulfate proteoglycans in neural stem cell–mediated repair in spinal cord injury28
The secondary injury cascade after spinal cord injury: an analysis of local cytokine/chemokine regulation28
Dysfunction of synaptic endocytic trafficking in Parkinson’s disease28
Post-acute ischemic stroke hyperglycemia aggravates destruction of the blood-brain barrier28
Letter from the Editor-in-Chief27
Semaphorin7A: its role in the control of serotonergic circuits and functional recovery following spinal cord injury27
Genetic and pathway complexity in Alzheimer’s disease: Insights from multi-omic data about the immune response and mitochondrial function27
Multiple sclerosis drug repurposing for neuroregeneration27
Metformin remodels the myelin landscape27
The critical role of the endolysosomal system in cerebral ischemia27
Small extracellular vesicles derived from cerebral endothelial cells with elevated microRNA 27a promote ischemic stroke recovery27
Schwann cell extracellular vesicles: judging a book by its cover27
Delayed activation of leg somatotopic fibers of an injured corticospinal tract in a patient with cerebral infarction27
Making bridges between preclinical and clinical insights into age-related cognitive decline26
Two become one: combination of two risk factors in a new glaucoma animal model26
Adipose mesenchymal stem cell-derived extracellular vesicles reduce glutamate-induced excitotoxicity in the retina26
Graphene oxide-composited chitosan scaffold contributes to functional recovery of injured spinal cord in rats26
Data and subject heterogeneity and data sharing: keys to translational success in spinal cord injury research?26
Facial reanimation with interposition nerve graft or masseter nerve transfer: a comparative retrospective study26
Tau’s function and dysfunction in the brain26
Imaging mass spectrometry: a molecular microscope for studying the role of lipids in Parkinson’s disease26
Effects of delayed repair of peripheral nerve injury on the spatial distribution of motor endplates in target muscle26
Bioactive material promotes long-distance regeneration of optic nerve to restore visual functions26
Carboplatin restores neuronal toxicity in FUS-linked amyotrophic lateral sclerosis26
Application value of biofluid-based biomarkers for the diagnosis and treatment of spinal cord injury26
Neuronal chemokines: new insights into neuronal communication after injury26
Schwann cells differentiated from skin-derived precursors provide neuroprotection via autophagy inhibition in a cellular model of Parkinson’s disease26
Knockout of Sirt2 alleviates traumatic brain injury in mice26
Complement activation kindles the transition of acute post-traumatic brain injury to a chronic inflammatory disease25
Current progress of mitochondrial therapy for neural regeneration25
Brain-derived cell-free DNA25
Emerging roles of astrocytes in blood-brain barrier disruption upon amyloid-beta insults in Alzheimer's disease25
Artificial nerve graft constructed by coculture of activated Schwann cells and human hair keratin for repair of peripheral nerve defects25
Differential distribution of PINK1 and Parkin in the primate brain implies distinct roles25
Interconnections between diabetic corneal neuropathy and diabetic retinopathy: diagnostic and therapeutic implications25
Clues from a missense mutation of the adenosine A1 receptor gene associated with early-onset Parkinson’s disease25
Transcranial electrical stimulation in neurological disease25
Low-intensity transcranial ultrasound neuromodulation promotes neuronal regeneration: A new hope for noninvasive treatment of neurodegenerative diseases25
Secretase inhibition in Alzheimer’s disease therapeutics reveals functional roles of amyloid-beta4225
Implication of gut microbiome in age-related macular degeneration25
Insights into the transcriptomic heterogeneity of brain endothelial cells in normal aging and Alzheimer’s disease25
5-Hydroxytryptamine: a potential therapeutic target in amyotrophic lateral sclerosis25
Matrin-3 dysfunction in myopathy and motor neuron degeneration25
Time-to-enrollment in clinical trials investigating neurological recovery in chronic spinal cord injury: observations from a systematic review and ClinicalTrials.gov database25
Effects of quercetin and its derivatives in in vivo models of neuroinflammation: A systematic review and meta-analysis25
Magnesium-L-threonate treats Alzheimer’s disease by modulating the microbiota-gut-brain axis25
Contribution of glial cells to the neuroprotective effects triggered by repetitive magnetic stimulation24
Role of microtubule dynamics in Wallerian degeneration and nerve regeneration after peripheral nerve injury24
Neural and Müller glial adaptation of the retina to photoreceptor degeneration24
Diabetic corneal neuropathy as a surrogate marker for diabetic peripheral neuropathy24
Biomaterial-based strategies: a new era in spinal cord injury treatment24
The “mitochondrial stress responses”: the “Dr. Jekyll and Mr. Hyde” of neuronal disorders24
Stiffness-tunable biomaterials provide a good extracellular matrix environment for axon growth and regeneration24
Microglial depletion impairs glial scar formation and aggravates inflammation partly by inhibiting STAT3 phosphorylation in astrocytes after spinal cord injury24
Oxidative stress in retinal pigment epithelium degeneration: from pathogenesis to therapeutic targets in dry age-related macular degeneration24
Neuronal autosis: the self-destructive side of autophagy involved in hypoxic-ischemic neuronal death24
Profile of the RNA in exosomes from astrocytes and microglia using deep sequencing: implications for neurodegeneration mechanisms24
Boosting proteolytic pathways as a treatment against glycation-derived damage in the brain?24
Heterogeneity of mature oligodendrocytes in the central nervous system24
Blood-brain barrier pathology in cerebral small vessel disease24
Fasudil-modified macrophages reduce inflammation and regulate the immune response in experimental autoimmune encephalomyelitis23
Mechanosensitive Piezo1 channel regulation of microglial cell function and implications to neurodegenerative diseases and neuroinflammation23
Striatum-specific mechanisms regulate neuronal cell cycle re-entry: the choice between life and death23
Neuron-neuron attraction shapes morphology and activity of tissue engineered brain constructs23
Fibrinogen’s potential role in connecting cerebrovascular abnormalities with glymphatic dysfunction in Alzheimer’s disease23
Deuterated dextromethorphan/quinidine for agitation in Alzheimer’s disease23
Retraction: Resveratrol inhibits matrix metalloproteinases to attenuate neuronal damage in cerebral ischemia: a molecular docking study exploring possible neuroprotection23
Anti-vascular endothelial growth factor drugs combined with laser photocoagulation maintain retinal ganglion cell integrity in patients with diabetic macular edema: study protocol for a prospective, n23
Post-transcriptional mechanisms controlling neurogenesis and direct neuronal reprogramming23
Brain-penetrating neurotrophic factor mimetics: HER-096 as a disease-modifying therapy for Parkinson’s disease23
Synaptic pathology in multiple sclerosis: a role for Nogo-A signaling in astrocytes?23
A novel viewpoint in glaucoma therapeutics: enriched environment23
Can foods influence the onset and progress of neurodegenerative diseases?23
Strategies to treat neurodegeneration in neuronal ceroid lipofuscinosis: a view onto the retina23
Actin(g) toward a revised understanding of the role of cytoskeletal dynamics in neuronal bioenergetics23
Transcranial photobiomodulation for the brain: a wide range of clinical applications23
The effects and potential of microglial polarization and crosstalk with other cells of the central nervous system in the treatment of Alzheimer’s disease23
Stable isotope labeling-mass spectrometry as a new approach to determine remyelination23
Cerebral dopamine neurotrophic factor transfection in dopamine neurons using neurotensin-polyplex nanoparticles reverses 6-hydroxydopamine-induced nigrostriatal neurodegeneration23
A novel approach in preventing vascular leakage and angiogenesis in wet age-related macular degeneration23
Brain and spinal cord trauma: what we know about the therapeutic potential of insulin growth factor 1 gene therapy23
Exploring the synergy of the eye-brain connection: neuromodulation approaches for neurodegenerative disorders through transcorneal electrical stimulation23
Optogenetic neuroregeneration23
MET receptor tyrosine kinase promotes the generation of functional synapses in adult cortical circuits22
Secretory autophagy in neurons: More than throwing out the trash?22
Targeting autophagy by polyphenols to prevent glycative stress-toxicity in the brain22
Magnetic resonance imaging focused on the ferritin heavy chain 1 reporter gene detects neuronal differentiation in stem cells22
Multifaceted superoxide dismutase 1 expression in amyotrophic lateral sclerosis patients: a rare occurrence?22
Krüppel-like factor 7 attenuates hippocampal neuronal injury after traumatic brain injury22
Deciphering the role of PGC-1α in neurological disorders: from mitochondrial dysfunction to synaptic failure22
Alpha-synuclein-induced upregulation of SKI family transcriptional corepressor 1: A new player in aging and Parkinson’s disease?22
Persistent alterations in gray matter in COVID-19 patients experiencing sleep disturbances: a 3-month longitudinal study22
From regenerative strategies to pharmacological approaches: can we fine-tune treatment for Parkinson’s disease?22
Circulating extracellular vesicles: friends and foes in neurodegeneration22
Activity-dependent remodeling of genome architecture in engram cells facilitates memory formation and recall22
Mitochondrial therapeutics and mitochondrial transfer for neurodegenerative diseases and aging22
The new wave of p75 neurotrophin receptor targeted therapies22
How mind-body therapies might reduce pathological features of Alzheimer’s disease22
How physical and motor training affect cognitive performance: lessons from an inflammatory molecule22
Inhibitory gamma-aminobutyric acidergic neurons in the anterior cingulate cortex participate in the comorbidity of pain and emotion22
Exosomes in stroke management: A promising paradigm shift in stroke therapy22
Neuroprotective effects of Alda-1 mitigate spinal cord injury in mice: involvement of Alda-1-induced ALDH2 activation-mediated suppression of reactive aldehyde mechanisms22
Astrocyte evolution and human specificity22
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