OOIR: Observatory of International Research

Papers

(The median citation count of International Journal of Oral Science is 21. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
A hierarchical vascularized engineered bone inspired by intramembranous ossification for mandibular regeneration	322
A comprehensive review on biomarkers associated with painful temporomandibular disorders	308
Dental stem cell-derived extracellular vesicles as promising therapeutic agents in the treatment of diseases	186
KLF6 facilitates differentiation of odontoblasts through modulating the expression of P21 in vitro	179
Loss of KDM4B impairs osteogenic differentiation of OMSCs and promotes oral bone aging	142
The effects of altered BMP4 signaling in first branchial-arch-derived murine embryonic orofacial tissues	116
Stem cell microencapsulation maintains stemness in inflammatory microenvironment	116
Disrupted tenogenesis in masseter as a potential cause of micrognathia	115
Difficult and complicated oral ulceration: an expert consensus guideline for diagnosis	99
A 3D-printed molybdenum-containing scaffold exerts dual pro-osteogenic and anti-osteoclastogenic effects to facilitate alveolar bone repair	82
miR-140-3p enhanced the osteo/odontogenic differentiation of DPSCs via inhibiting KMT5B under hypoxia condition	72
Biomechanical and biological responses of periodontium in orthodontic tooth movement: up-date in a new decade	61
Analyses of oligodontia phenotypes and genetic etiologies	59
Hard tissue stability after guided bone regeneration: a comparison between digital titanium mesh and resorbable membrane	57
Retrograde nerve growth factor signaling modulates tooth mechanical hyperalgesia induced by orthodontic tooth movement via acid-sensing ion channel 3	51
Exosomes rewire the cartilage microenvironment in osteoarthritis: from intercellular communication to therapeutic strategies	50
Chromatin conformation of human oral epithelium can identify orofacial cleft missing functional variants	44
Cigarette smoke promotes oral leukoplakia via regulating glutamine metabolism and M2 polarization of macrophage	38
The enhanced genomic 6 mA metabolism contributes to the proliferation and migration of TSCC cells	38
PTHrP promotes subchondral bone formation in TMJ-OA	37
Oral microbiota in human systematic diseases	36
The vicK gene of Streptococcus mutans mediates its cariogenicity via exopolysaccharides metabolism	36
Expert consensus on early childhood caries management	36
Fibroblast membrane-camouflaged nanoparticles for inflammation treatment in the early stage	35
From bulk, single-cell to spatial RNA sequencing	34

Identification of BRAF V600E mutation in odontogenic tumors by high-performance MALDI-TOF analysis	33
SPDEF suppresses head and neck squamous cell carcinoma progression by transcriptionally activating NR4A1	32
The role of dendritic cells in the immunomodulation to implanted biomaterials	31
Advances in regenerative medicine applications of tetrahedral framework nucleic acid-based nanomaterials: an expert consensus recommendation	29
Aberrant NF-κB activation in odontoblasts orchestrates inflammatory matrix degradation and mineral resorption	28
Exosomes derived from 3D-cultured MSCs improve therapeutic effects in periodontitis and experimental colitis and restore the Th17 cell/Treg balance in inflamed periodontium	26
Extrapolating neurogenesis of mesenchymal stem/stromal cells on electroactive and electroconductive scaffolds to dental and oral-derived stem cells	25
Tumor microenvironment and immune evasion in head and neck squamous cell carcinoma	25
Methyltransferase like 13 mediates the translation of Snail in head and neck squamous cell carcinoma	24
Porphyromonas gingivalis infection promotes mitochondrial dysfunction through Drp1-dependent mitochondrial fission in endothelial cells	23
Periodontitis may induce gut microbiota dysbiosis via salivary microbiota	23
Correction to: Porphyromonas gingivalis infection promotes mitochondrial dysfunction through Drp1-dependent mitochondrial fission in endothelial cells	22
Sphingosine-1-phosphate hinders the osteogenic differentiation of dental pulp stem cells in association with AKT signaling pathways	22
Advances in biomineralization-inspired materials for hard tissue repair	22
Effect of PAIP1 on the metastatic potential and prognostic significance in oral squamous cell carcinoma	22
Molecular mechanisms of inhibiting glucosyltransferases for biofilm formation in Streptococcus mutans	22
External cervical resorption—a review of pathogenesis and potential predisposing factors	21
Indigenous microbiota protects development of medication-related osteonecrosis induced by periapical disease in mice	21
Single-cell characterization of monolayer cultured human dental pulp stem cells with enhanced differentiation capacity	21