OOIR: Observatory of International Research

Papers

(The TQCC of Protein & Cell is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Oncomicrobial vaccines mitigate tumor progression via precisely targeting oncomicrobes in mice	292
Unfolding HBx for an epigenetic switch of HBV cccDNA minichromosome	156
IL-24 promotes atopic dermatitis-like inflammation through driving MRSA-induced allergic responses	124
Metabolic cell death in cancer: ferroptosis, cuproptosis, disulfidptosis, and beyond	112
“Always learn today, stand ready to act tomorrow”—Po Tien: A pioneer of Virology in China	104
The Host Microbiota is Associated with the Occurrence and Development of Esophageal Squamous Cell Carcinoma	101
Ko Kuei Chen: A Pioneer of Modern Pharmacological Research in China	83
In memory of the well-renowned Chinese cellular biologist Shien Sher-Pu	74
Single-cell analysis reveals an Angpt4-initiated EPDC-EC-CM cellular coordination cascade during heart regeneration	55
Zhu Xi: A Pioneer of Experimental Biology	52
Cell-cycle length of medial ganglionic eminence progenitors contributes to interneuron fate	49
Dual role of lipids for genome stability and pluripotency facilitates full potency of mouse embryonic stem cells	46
METTL14 is a chromatin regulator independent of its RNA N 6-methyladenosine methyltransferase activity	43
Correction to: Oncogenic miR-19a and miR-19b co-regulate tumor suppressor MTUS1 to promote cell proliferation and migration in lung cancer	43
Jiangsen Mao: a pioneer in Chinese hepatitis A vaccine and interferon research, a virologist at the forefront of times	41
Targeting IRG1 in tumor-associated macrophages for cancer therapy	36
Gene print-based cell subtypes annotation of human disease across heterogeneous datasets with gPRINT	35
Architecture of severe fever with thrombocytopenia syndrome virus	33
Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration	32
Isogenic human pluripotent stem cell disease models reveal ABRA deficiency underlies cTnT mutation-induced familial dilated cardiomyopathy	31
Gut microbial methionine impacts circadian clock gene expression and reactive oxygen species level in host gastrointestinal tract	26
Remembering the Scholar Ding Ying: The Father of Chinese Rice-Farming Science	25
Bilineage embryo-like structure from EPS cells can produce live mice with tetraploid trophectoderm	24
Correction to: CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-κB/RelA in maintaining the homeostasis of human vascular cells	24
Asymmetric reconstruction of the aquareovirus core at near-atomic resolution and mechanism of transcription initiation	22

Microbiome research outlook: past, present, and future	22
Anthrax lethal toxin and tumor necrosis factor-α synergize on intestinal epithelia to induce mouse death	22
DCK confers sensitivity of DCTD-positive cancer cells to oxidized methylcytidines	21
A core epitope targeting antibody of SARS-CoV-2	21
Resolving the lineage relationship between malignant cells and vascular cells in glioblastomas	20
Structural basis for polyuridine tract recognition by SARS-CoV-2 Nsp15	20
Spatially-resolved expression landscape and gene-regulatory network of human gastric corpus epithelium	18
Exploring unconventional attributes of red blood cells and their potential applications in biomedicine	18
Boundless love: a German Professor Uli Schwarz in China	18
Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse model	17
Pan Shuh: the founding figure of modern Chinese psychology	17
Identification of FOXO1 as a geroprotector in human synovium through single-nucleus transcriptomic profiling	17
An improved method for the detection of double-stranded RNA suitable for quality control of mRNA vaccines	16
Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging	15
CRL3 E3 ligase regulates glutamine and cystine metabolisms	14
Richard Ho-Ping Sia: pioneer of infectiology in China	14
ARID1A IDR targets EWS-FLI1 condensates and finetunes chromatin remodeling	13
Persisting lung pathogenesis and minimum residual virus in hamster after acute COVID-19	13
METTL9 mediated N1-histidine methylation of zinc transporters is required for tumor growth	13
Endoplasmic reticulum membrane remodeling by targeting reticulon-4 induces pyroptosis to facilitate antitumor immune	13
A third dose of inactivated vaccine augments the potency, breadth, and duration of anamnestic responses against SARS-CoV-2	12
Cancer biology deciphered by single-cell transcriptomic sequencing	12
Correction to: The nucleocapsid protein of rice stripe virus in cell nuclei of vector insect regulates viral replication	12
JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells	11
Molecular deconvolution of the neutralizing antibodies induced by an inactivated SARS-CoV-2 virus vaccine	11
4E-BP1 counteracts human mesenchymal stem cell senescence via maintaining mitochondrial homeostasis	11
Single-cell transcriptomic Atlas of mouse cochlear aging	11
MFSD12 affects glycosphingolipid metabolism by modulating lysosome homeostasis	11
Alzheimer’s disease: insights into pathology, molecular mechanisms, and therapy	11
Recent progress and challenges in the treatment of spinal cord injury	11
Sung Shu Chien: The founder of modern Chinese botany	11
Two antibodies show broad, synergistic neutralization against SARS-CoV-2 variants by inducing conformational change within the RBD	10
Mechanistic insights into the GEF activity of the human MON1A/CCZ1/C18orf8 complex	10
Professor Delong Su: a pioneer in Schistosomiasis Eradication in China	10
Maternal heterozygous mutation in CHEK1 leads to mitotic arrest in human zygotes	10
Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses	9
Skeletal stem cells in bone development, homeostasis, and disease	9
Follicle stimulating hormone controls granulosa cell glutamine synthesis to regulate ovulation	8
p21/Zbtb18 repress the expression of cKit to regulate the self-renewal of hematopoietic stem cells	8
Strategies for generating mouse model resources of human disease	8
Tanjun Tong: a pioneer of cellular senescence and aging mechanism research in China	8
RBM46 is essential for gametogenesis and functions in post-transcriptional roles affecting meiotic cohesin subunits	8
CARM1 drives triple-negative breast cancer progression by coordinating with HIF1A	8