OOIR: Observatory of International Research

Papers

(The TQCC of Protein & Cell is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
“Always learn today, stand ready to act tomorrow”—Po Tien: A pioneer of Virology in China	185
Withdrawn as Duplicate: Remembering the Scholar Ding Ying: The Father of Chinese Rice-Farming Science	165
Pan Shuh: the founding figure of modern Chinese psychology	84
Gene print-based cell subtypes annotation of human disease across heterogeneous datasets with gPRINT	84
Unfolding HBx for an epigenetic switch of HBV cccDNA minichromosome	83
An improved method for the detection of double-stranded RNA suitable for quality control of mRNA vaccines	79
Microbiome research outlook: past, present, and future	68
ARID1A IDR targets EWS-FLI1 condensates and finetunes chromatin remodeling	61
Architecture of severe fever with thrombocytopenia syndrome virus	51
DCK confers sensitivity of DCTD-positive cancer cells to oxidized methylcytidines	50
One step, two functions: the mechanism of the ABCH class of transporter serving barrier construction and detoxification in insects	48
Spatially-resolved expression landscape and gene-regulatory network of human gastric corpus epithelium	45
JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells	37
Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging	36
Anthrax lethal toxin and tumor necrosis factor-α synergize on intestinal epithelia to induce mouse death	35
Endoplasmic reticulum membrane remodeling by targeting reticulon-4 induces pyroptosis to facilitate antitumor immune	34
Gut microbial methionine impacts circadian clock gene expression and reactive oxygen species level in host gastrointestinal tract	32
Inheritance and advancement in biochemistry: the pioneering research of Szu-Chih Liu	32
Dynamin 1-mediated endocytic recycling of glycosylated N-cadherin sustains the plastic mesenchymal state to promote ovarian cancer metastasis	32
Strategies for generating mouse model resources of human disease	27
Efficient CRISPR-based gene activation using combinatorial human transcription activation domains	27
Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses	25
A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions	24
Mutations in the SARS-CoV-2 spike receptor binding domain and their delicate balance between ACE2 affinity and antibody evasion	24
Correction to: Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer	24

A single-cell transcriptomic landscape characterizes the endocrine system aging in the mouse	24
A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 omicronin vivo	22
Pasteurized Akkermansia muciniphila promotes GP2 expression in microfold cells and facilitates Salmonella infection	20
Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy	20
A tribute to Professor Yong Zhao	20
An orally-available monovalent SMAC mimetic compound as a broad-spectrum antiviral	20
Correction to: SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer	19
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors	18
Long-term in vivo chimeric cells tracking in non-human primate	18
Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine	18
Accumulation of newly synthesized docosahexaenoic acid plays an essential role in heart regeneration	17
Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis	17
Advances in gene and cellular therapeutic approaches for Huntington’s disease	16
Secreted proteins in treating metabolic dysfunction-associated steatotic liver disease: from bench towards bedside	16
Single transmembrane GPCR modulating proteins: neither single nor simple	16
Radiation injury and gut microbiota-based treatment	16
Glutamine signaling specifically activates c-Myc and Mcl-1 to facilitate cancer cell proliferation and survival	16
Microbial sensing in the intestine	16
Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	16
Hunting out the repeat expansion in Huntington’s pigs	16
SMURF1: a promising target for colon cancer therapy	16
Endosomal catabolism of phosphatidylinositol 4,5-bisphosphate is fundamental in building resilience against pathogens	15
Modeling hepatoblastoma development with human fetal liver organoids reveals YAP1 activation is sufficient for tumorigenesis	14
Correction to: Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	14
The microbiota–gut–brain axis and neurodevelopmental disorders	14
Systematicidentification of CRISPR off-target effects by CROss-seq	14
Boundless love: a German Professor Uli Schwarz in China	13
Systematic characterization of full-length RNA isoforms in human colorectal cancer at single-cell resolution	12
Synergistic innovation in organ-on-a-chip and organoid technologies: reshaping the future of disease modeling, drug development, and precision medicine	12
Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse model	12
Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration	11
Tanjun Tong: a pioneer of cellular senescence and aging mechanism research in China	11
Oncogenic role of the SLC7A13-SLC3A1 cystine transporter in human luminal breast cancer and its cryo-EM structure	11
Sung Shu Chien: The founder of modern Chinese botany	11
Degeneration Directory: a multi-omics web resource for degenerative diseases	11
Syn3, a newly developed cyclic peptide and BDNF signaling enhancer, ameliorates retinal ganglion cell degeneration in diabetic retinopathy	10
Epigenetic integrity of paternal imprints enhances the developmental potential of androgenetic haploid embryonic stem cells	10
Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging	10
Governing glutaminolysis by regulation of glutaminase succinylation	10
Correction to: Endothelial-to-Osteoblast Conversion maintains bone homeostasis through Kindlin-2/Piezo1/TGFβ/Runx2 axis	10
Structural studies promote vaccine development: lessons from African swine fever virus	10
A molecular brake that modulates spliceosome pausing at detained introns contributes to neurodegeneration	9
Join the club: ORP8 is a lipophagy receptor	9
Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner	9
Virological research history in China: a century of profiling virologists’ contributions and virological innovations	9
The chordata olfactory receptor database	9
PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis	8
Bardoxolone methyl blocks the efflux of Zn2+ by targeting hZnT1 to inhibit the proliferation and metastasis of cervical cancer	8
Platelet RNA enables accurate detection of ovarian cancer: an intercontinental, biomarker identification study	8
RNA helicase MTR4 drives tumorigenesis of nasopharyngeal carcinoma by regulating the expression of key cell cycle genes	8

mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells	8
Cryo-EM structure of human κ-opioid receptor-Gi complex bound to an endogenous agonist dynorphin A	8
Single-nucleus profiling unveils a geroprotective role of the FOXO3 in primate skeletal muscle aging	8