OOIR: Observatory of International Research

Papers

(The TQCC of Protein & Cell is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Withdrawn as Duplicate: Remembering the Scholar Ding Ying: The Father of Chinese Rice-Farming Science	299
Gene print-based cell subtypes annotation of human disease across heterogeneous datasets with gPRINT	265
Pan Shuh: the founding figure of modern Chinese psychology	168
DCK confers sensitivity of DCTD-positive cancer cells to oxidized methylcytidines	145
One step, two functions: the mechanism of the ABCH class of transporter serving barrier construction and detoxification in insects	122
Gut microbial methionine impacts circadian clock gene expression and reactive oxygen species level in host gastrointestinal tract	111
JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells	80
Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging	76
ARID1A IDR targets EWS-FLI1 condensates and finetunes chromatin remodeling	66
Spatially-resolved expression landscape and gene-regulatory network of human gastric corpus epithelium	66
DHA, a potentially therapeutic lipid for myocardial infarction	59
Microbiome research outlook: past, present, and future	59
Endoplasmic reticulum membrane remodeling by targeting reticulon-4 induces pyroptosis to facilitate antitumor immune	50
Architecture of severe fever with thrombocytopenia syndrome virus	50
Anthrax lethal toxin and tumor necrosis factor-α synergize on intestinal epithelia to induce mouse death	49
An improved method for the detection of double-stranded RNA suitable for quality control of mRNA vaccines	48
Dynamin 1-mediated endocytic recycling of glycosylated N-cadherin sustains the plastic mesenchymal state to promote ovarian cancer metastasis	46
Unfolding HBx for an epigenetic switch of HBV cccDNA minichromosome	46
Inheritance and advancement in biochemistry: the pioneering research of Szu-Chih Liu	40
Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses	39
3D chromatin dynamics in cellular neuroendocrine transformation	36
Mutations in the SARS-CoV-2 spike receptor binding domain and their delicate balance between ACE2 affinity and antibody evasion	34
Efficient clustered, regularly interspaced short palindromic repeats-based gene activation using combinatorial human transcription activation domains	33
NSUN2‑mediated epitranscriptomic and ubiquitin modulation of Nipah virus matrix protein reveals a dual-targeting antiviral strategy	31
A single-cell transcriptomic landscape characterizes the endocrine system aging in the mouse	31

Strategies for generating mouse model resources of human disease	30
An orally-available monovalent SMAC mimetic compound as a broad-spectrum antiviral	30
A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions	30
Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy	29
A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 omicronin vivo	29
Restoring the FOXO1 geroprotective pathway via seno-resistant mesenchymal progenitor cells alleviates primate epididymal aging	28
Correction to: Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer	27
Pasteurized Akkermansia muciniphila promotes GP2 expression in microfold cells and facilitates Salmonella infection	27
Correction to: SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer	26
Long-term in vivo chimeric cells tracking in non-human primate	26
Tuning the Hsp70 chaperone cycle: emerging roles of GrpE-like nucleotide exchange factors in proteostasis and organelle function	26
Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine	26
Primate abnormal spindle-like microcephaly-associated knockout causes severe microcephaly and oligodendrocyte loss in the brain	24
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors	24
Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	23
Advances in gene and cellular therapeutic approaches for Huntington’s disease	23
Accumulation of newly synthesized docosahexaenoic acid plays an essential role in heart regeneration	23
What we can learn from hibernators and other adapted animals about organ transplantation: mechanisms of cold resistance and enhanced regeneration	23
Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis	22
Radiation injury and gut microbiota-based treatment	21
Microbial sensing in the intestine	21
Tumor cell GPX4 dictates triacylglycerol metabolism for ferroptosis susceptibility and immune evasion of NSCLC	19
Endosomal catabolism of phosphatidylinositol 4,5-bisphosphate is fundamental in building resilience against pathogens	19
Single transmembrane GPCR modulating proteins: neither single nor simple	18
SMURF1: a promising target for colon cancer therapy	17
Hunting out the repeat expansion in Huntington’s pigs	17
Systematicidentification of CRISPR off-target effects by CROss-seq	17
Correction to: Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	17
Glutamine signaling specifically activates c-Myc and Mcl-1 to facilitate cancer cell proliferation and survival	16
The microbiota–gut–brain axis and neurodevelopmental disorders	16
MANF is essential for astrocyte survival in the monkey brain	16
Boundless love: a German Professor Uli Schwarz in China	16
Secreted proteins in treating metabolic dysfunction-associated steatotic liver disease: from bench towards bedside	16
Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration	15
Synergistic innovation in organ-on-a-chip and organoid technologies: reshaping the future of disease modeling, drug development, and precision medicine	15
Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse model	15
Systematic characterization of full-length RNA isoforms in human colorectal cancer at single-cell resolution	14
Correction to: DHA, a potentially therapeutic lipid for myocardial infarction	14
Oncogenic role of the SLC7A13-SLC3A1 cystine transporter in human luminal breast cancer and its cryo-EM structure	14
Sung Shu Chien: The founder of modern Chinese botany	13
Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging	13
Tanjun Tong: a pioneer of cellular senescence and aging mechanism research in China	13
Syn3, a newly developed cyclic peptide and BDNF signaling enhancer, ameliorates retinal ganglion cell degeneration in diabetic retinopathy	13
Degeneration Directory: a multi-omics web resource for degenerative diseases	13
The chordata olfactory receptor database	12
Structural studies promote vaccine development: lessons from African swine fever virus	12
A molecular brake that modulates spliceosome pausing at detained introns contributes to neurodegeneration	12
Virological research history in China: a century of profiling virologists’ contributions and virological innovations	12
Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner	12
Correction to: Endothelial-to-Osteoblast Conversion maintains bone homeostasis through Kindlin-2/Piezo1/TGFβ/Runx2 axis	12

Join the club: ORP8 is a lipophagy receptor	11
Cryo-EM structure of human κ-opioid receptor-Gi complex bound to an endogenous agonist dynorphin A	11
Platelet RNA signature independently predicts ovarian cancer prognosis by deep learning neural network model	11
Structural basis of INTAC-regulated transcription	11
Whole-exome sequencing identifies ECPAS as a novel potentially pathogenic gene in multiple hereditary families with nonsyndromic orofacial cleft	10
Kechun Lin: a pioneer of biophysics explorations in China	10
Bardoxolone methyl blocks the efflux of Zn2+ by targeting hZnT1 to inhibit the proliferation and metastasis of cervical cancer	10
RNA helicase MTR4 drives tumorigenesis of nasopharyngeal carcinoma by regulating the expression of key cell cycle genes	10
Platelet RNA enables accurate detection of ovarian cancer: an intercontinental, biomarker identification study	10
Gut dysbiosis impairs intestinal renewal and lipid absorption in Scarb2 deficiency-associated neurodegeneration	10
The role of parkin in monkey	10
Molecular basis of high-torque transmission of the Vibrio polar flagellar motor	9
The unexpected role of RagC in ketogenic diet-derived BHB sensing	9
MMP-9 regulates disulphide isomerase activity of TGM2 to enhance fusion glycoprotein-mediated syncytium formation of respiratory syncytial virus	9
PDHX acetylation facilitates tumor progression by disrupting PDC assembly and activating lactylation-mediated gene expression	9
Single-nucleus profiling unveils a geroprotective role of the FOXO3 in primate skeletal muscle aging	9
The chemical reprogramming of unipotent adult germ cells towards authentic pluripotency and de novo establishment of imprinting	9
Ergothioneine and its congeners: anti-ageing mechanisms and pharmacophore biosynthesis	9