OOIR: Observatory of International Research

Papers

(The TQCC of Protein & Cell is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
“Always learn today, stand ready to act tomorrow”—Po Tien: A pioneer of Virology in China	158
Gut microbial methionine impacts circadian clock gene expression and reactive oxygen species level in host gastrointestinal tract	122
DCK confers sensitivity of DCTD-positive cancer cells to oxidized methylcytidines	112
Pan Shuh: the founding figure of modern Chinese psychology	85
Anthrax lethal toxin and tumor necrosis factor-α synergize on intestinal epithelia to induce mouse death	65
Gene print-based cell subtypes annotation of human disease across heterogeneous datasets with gPRINT	55
Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging	52
Remembering the Scholar Ding Ying: The Father of Chinese Rice-Farming Science	52
Endoplasmic reticulum membrane remodeling by targeting reticulon-4 induces pyroptosis to facilitate antitumor immune	49
Spatially-resolved expression landscape and gene-regulatory network of human gastric corpus epithelium	46
One step, two functions: The mechanism of the ABCH class of transporter serving barrier construction and detoxification in insects	45
Architecture of severe fever with thrombocytopenia syndrome virus	42
Cancer biology deciphered by single-cell transcriptomic sequencing	42
ARID1A IDR targets EWS-FLI1 condensates and finetunes chromatin remodeling	40
Unfolding HBx for an epigenetic switch of HBV cccDNA minichromosome	36
JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells	35
An improved method for the detection of double-stranded RNA suitable for quality control of mRNA vaccines	32
Microbiome research outlook: past, present, and future	30
Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses	30
Dynamin 1-mediated endocytic recycling of glycosylated N-cadherin sustains the plastic mesenchymal state to promote ovarian cancer metastasis	29
An ultrapotent pan-β-coronavirus lineage B (β-CoV-B) neutralizing antibody locks the receptor-binding domain in closed conformation by targeting its conserved epitope	29
Mutations in the SARS-CoV-2 spike receptor binding domain and their delicate balance between ACE2 affinity and antibody evasion	25
Inheritance and advancement in biochemistry: the pioneering research of Szu-Chih Liu	25
Strategies for generating mouse model resources of human disease	24
A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 omicronin vivo	24

An orally-available monovalent SMAC mimetic compound as a broad-spectrum antiviral	23
A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions	23
Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy	23
Pasteurized Akkermansia muciniphila promotes GP2 expression in microfold cells and facilitates Salmonella infection	22
Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine	21
A tribute to Professor Yong Zhao	20
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors	19
Long-term in vivo chimeric cells tracking in non-human primate	19
Correction to: SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer	19
RNA m6A meets transposable elements and chromatin	18
Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	17
Microbial sensing in the intestine	15
Advances in gene and cellular therapeutic approaches for Huntington’s disease	15
Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis	15
Radiation injury and gut microbiota-based treatment	15
Endosomal catabolism of phosphatidylinositol 4,5-bisphosphate is fundamental in building resilience against pathogens	14
Correction to: Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	14
Hunting out the repeat expansion in Huntington’s pigs	14
SMURF1: a promising target for colon cancer therapy	13
Modeling hepatoblastoma development with human fetal liver organoids reveals YAP1 activation is sufficient for tumorigenesis	13
Glutamine signaling specifically activates c-Myc and Mcl-1 to Facilitate cancer cell proliferation and survival	13
Secreted proteins in treating metabolic dysfunction-associated steatotic liver disease: from bench towards bedside	13
Systematicidentification of CRISPR off-target effects by CROss-seq	13
Single transmembrane GPCR modulating proteins: neither single nor simple	13
The microbiota–gut–brain axis and neurodevelopmental disorders	12
Boundless love: a German Professor Uli Schwarz in China	12
Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse model	11
Degeneration Directory: a multi-omics web resource for degenerative diseases	11
Correction to: The nucleocapsid protein of rice stripe virus in cell nuclei of vector insect regulates viral replication	11
Sung Shu Chien: The founder of modern Chinese botany	11
Syn3, a newly developed cyclic peptide and BDNF signaling enhancer, ameliorates retinal ganglion cell degeneration in diabetic retinopathy	11
Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration	11
Tanjun Tong: a pioneer of cellular senescence and aging mechanism research in China	11
mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells	10
Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging	10
Epigenetic integrity of paternal imprints enhances the developmental potential of androgenetic haploid embryonic stem cells	10
Join the club: ORP8 is a lipophagy receptor	10
A molecular brake that modulates spliceosome pausing at detained introns contributes to neurodegeneration	10
PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis	9
Virological research history in China: a century of profiling virologists’ contributions and virological innovations	9
Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner	9
The chordata olfactory receptor database	9
Governing glutaminolysis by regulation of glutaminase succinylation	9