OOIR: Observatory of International Research

Papers

(The TQCC of Protein & Cell is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Withdrawn as Duplicate: Remembering the Scholar Ding Ying: The Father of Chinese Rice-Farming Science	219
Gene print-based cell subtypes annotation of human disease across heterogeneous datasets with gPRINT	131
Pan Shuh: the founding figure of modern Chinese psychology	110
DHA, a potentially therapeutic lipid for myocardial infarction	102
One step, two functions: the mechanism of the ABCH class of transporter serving barrier construction and detoxification in insects	95
Single-nucleus transcriptomics reveals a gatekeeper role for FOXP1 in primate cardiac aging	80
JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells	59
DCK confers sensitivity of DCTD-positive cancer cells to oxidized methylcytidines	56
Spatially-resolved expression landscape and gene-regulatory network of human gastric corpus epithelium	54
Gut microbial methionine impacts circadian clock gene expression and reactive oxygen species level in host gastrointestinal tract	42
ARID1A IDR targets EWS-FLI1 condensates and finetunes chromatin remodeling	41
Anthrax lethal toxin and tumor necrosis factor-α synergize on intestinal epithelia to induce mouse death	39
Unfolding HBx for an epigenetic switch of HBV cccDNA minichromosome	39
An improved method for the detection of double-stranded RNA suitable for quality control of mRNA vaccines	37
Architecture of severe fever with thrombocytopenia syndrome virus	36
Endoplasmic reticulum membrane remodeling by targeting reticulon-4 induces pyroptosis to facilitate antitumor immune	35
Microbiome research outlook: past, present, and future	31
Inheritance and advancement in biochemistry: the pioneering research of Szu-Chih Liu	29
Strategies for generating mouse model resources of human disease	28
3D chromatin dynamics in cellular neuroendocrine transformation	28
Dynamin 1-mediated endocytic recycling of glycosylated N-cadherin sustains the plastic mesenchymal state to promote ovarian cancer metastasis	26
A single-cell transcriptomic landscape characterizes the endocrine system aging in the mouse	26
Cryo-EM structures of Nipah virus polymerase complex reveal highly varied interactions between L and P proteins among paramyxoviruses	25
Efficient clustered, regularly interspaced short palindromic repeats-based gene activation using combinatorial human transcription activation domains	25
Mutations in the SARS-CoV-2 spike receptor binding domain and their delicate balance between ACE2 affinity and antibody evasion	25

A long non-coding RNA LncSync regulates mouse cardiomyocyte homeostasis and cardiac hypertrophy through coordination of miRNA actions	24
Correction to: Genome-wide CRISPR screen identifies synthetic lethality between DOCK1 inhibition and metformin in liver cancer	23
A hnRNPA2B1 agonist effectively inhibits HBV and SARS-CoV-2 omicronin vivo	22
Immune rebalancing at the maternal-fetal interface of maternal SARS-CoV-2 infection during early pregnancy	21
An orally-available monovalent SMAC mimetic compound as a broad-spectrum antiviral	21
High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors	20
Correction to: SIRT7 antagonizes human stem cell aging as a heterochromatin stabilizer	20
Long-term in vivo chimeric cells tracking in non-human primate	20
Pasteurized Akkermansia muciniphila promotes GP2 expression in microfold cells and facilitates Salmonella infection	20
Primate ASPM knockout causes severe microcephaly and oligodendrocyte loss in the brain	19
Tuning the Hsp70 chaperone cycle: emerging roles of GrpE-like NEFs in proteostasis and organelle function	19
Oxidative phosphorylation safeguards pluripotency via UDP-N-acetylglucosamine	18
Advances in gene and cellular therapeutic approaches for Huntington’s disease	18
Radiation injury and gut microbiota-based treatment	18
Proteomic analysis of ferroptosis pathways reveals a role of CEPT1 in suppressing ferroptosis	17
Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	17
Microbial sensing in the intestine	17
Accumulation of newly synthesized docosahexaenoic acid plays an essential role in heart regeneration	17
Secreted proteins in treating metabolic dysfunction-associated steatotic liver disease: from bench towards bedside	16
Hunting out the repeat expansion in Huntington’s pigs	16
Endosomal catabolism of phosphatidylinositol 4,5-bisphosphate is fundamental in building resilience against pathogens	15
Systematicidentification of CRISPR off-target effects by CROss-seq	14
Correction to: Adenosine-to-inosine RNA editing in cancer: molecular mechanisms and downstream targets	14
Modeling hepatoblastoma development with human fetal liver organoids reveals YAP1 activation is sufficient for tumorigenesis	14
SMURF1: a promising target for colon cancer therapy	13
Single transmembrane GPCR modulating proteins: neither single nor simple	13
Systematic characterization of full-length RNA isoforms in human colorectal cancer at single-cell resolution	13
The microbiota–gut–brain axis and neurodevelopmental disorders	13
Boundless love: a German Professor Uli Schwarz in China	13
Glutamine signaling specifically activates c-Myc and Mcl-1 to facilitate cancer cell proliferation and survival	13
Oncogenic role of the SLC7A13-SLC3A1 cystine transporter in human luminal breast cancer and its cryo-EM structure	12
Synergistic innovation in organ-on-a-chip and organoid technologies: reshaping the future of disease modeling, drug development, and precision medicine	12
Single-cell profiling reveals a potent role of quercetin in promoting hair regeneration	10
Sung Shu Chien: The founder of modern Chinese botany	10
Aberrant outputs of cerebellar nuclei and targeted rescue of social deficits in an autism mouse model	10
Correction to: Endothelial-to-Osteoblast Conversion maintains bone homeostasis through Kindlin-2/Piezo1/TGFβ/Runx2 axis	10
Structural studies promote vaccine development: lessons from African swine fever virus	10
Tanjun Tong: a pioneer of cellular senescence and aging mechanism research in China	10
Syn3, a newly developed cyclic peptide and BDNF signaling enhancer, ameliorates retinal ganglion cell degeneration in diabetic retinopathy	10
Degeneration Directory: a multi-omics web resource for degenerative diseases	10
Governing glutaminolysis by regulation of glutaminase succinylation	9
Join the club: ORP8 is a lipophagy receptor	9
Epigenetic integrity of paternal imprints enhances the developmental potential of androgenetic haploid embryonic stem cells	9
Virological research history in China: a century of profiling virologists’ contributions and virological innovations	9
Single-nucleus transcriptomics uncovers a geroprotective role of YAP in primate gingival aging	9
mTORC2/RICTOR exerts differential levels of metabolic control in human embryonic, mesenchymal and neural stem cells	8
Single-nucleus profiling unveils a geroprotective role of the FOXO3 in primate skeletal muscle aging	8
Platelet RNA signature independently predicts ovarian cancer prognosis by deep learning neural network model	8
A molecular brake that modulates spliceosome pausing at detained introns contributes to neurodegeneration	8
The chordata olfactory receptor database	8

Bardoxolone methyl blocks the efflux of Zn2+ by targeting hZnT1 to inhibit the proliferation and metastasis of cervical cancer	8
The role of parkin in monkey	8
Cryo-EM structure of human κ-opioid receptor-Gi complex bound to an endogenous agonist dynorphin A	8
Whole-exome sequencing identifies ECPAS as a novel potentially pathogenic gene in multiple hereditary families with nonsyndromic orofacial cleft	8
Human ESC-derived vascular cells promote vascular regeneration in a HIF-1α dependent manner	8