BMC Biology

Article	Citations
An updated tribal classification of Lamiaceae based on plastome phylogenomics	129
Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions	111
Plastid phylogenomic insights into relationships of all flowering plant families	111
Plasma membrane integrity: implications for health and disease	96
Altered brain-wide auditory networks in a zebrafish model of fragile X syndrome	92
Tandem gene duplications drive divergent evolution of caffeine and crocin biosynthetic pathways in plants	86
ONTbarcoder and MinION barcodes aid biodiversity discovery and identification by everyone, for everyone	83
Modified nucleic acids: replication, evolution, and next-generation therapeutics	80
Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly	76
Comparison of 15 dinoflagellate genomes reveals extensive sequence and structural divergence in family Symbiodiniaceae and genus Symbiodinium	67
Modelling the suppression of a malaria vector using a CRISPR-Cas9 gene drive to reduce female fertility	67
Winter is coming: the future of cryopreservation	65
Genomes of the dinoflagellate Polarella glacialis encode tandemly repeated single-exon genes with adaptive functions	64
FGF-2 promotes angiogenesis through a SRSF1/SRSF3/SRPK1-dependent axis that controls VEGFR1 splicing in endothelial cells	55
New targeted approaches for epigenetic age predictions	53
The replication machinery of LUCA: common origin of DNA replication and transcription	53
A tissue level atlas of the healthy human virome	52
Genome-enabled insights into the biology of thrips as crop pests	52
Prokaryotic virus host predictor: a Gaussian model for host prediction of prokaryotic viruses in metagenomics	50
The hard clam genome reveals massive expansion and diversification of inhibitors of apoptosis in Bivalvia	49
The rise of diversity in metabolic platforms across the Candidate Phyla Radiation	48
Genome-wide pQTL analysis of protein expression regulatory networks in the human liver	47
Genome sequencing sheds light on the contribution of structural variants to Brassica oleracea diversification	47
Long-term live imaging and multiscale analysis identify heterogeneity and core principles of epithelial organoid morphogenesis	47
Differential loss of effector genes in three recently expanded pandemic clonal lineages of the rice blast fungus	46

Unraveling the molecular interactions involved in phase separation of glucocorticoid receptor	45
Long-term persistence of crAss-like phage crAss001 is associated with phase variation in Bacteroides intestinalis	45
Extreme mobility of the world’s largest flying mammals creates key challenges for management and conservation	45
Putative ligand binding sites of two functionally characterized bark beetle odorant receptors	45
Large-scale discovery of male reproductive tract-specific genes through analysis of RNA-seq datasets	44
Genomic evidence for a hybrid origin of the yeast opportunistic pathogen Candida albicans	44
Reorganization of the 3D chromatin architecture of rice genomes during heat stress	44
Evolutionary analyses of the gasdermin family suggest conserved roles in infection response despite loss of pore-forming functionality	43
Discordant evolution of mitochondrial and nuclear yeast genomes at population level	42
Sphenodontian phylogeny and the impact of model choice in Bayesian morphological clock estimates of divergence times and evolutionary rates	41
ACBE, a new base editor for simultaneous C-to-T and A-to-G substitutions in mammalian systems	41
Autochthonous faecal viral transfer (FVT) impacts the murine microbiome after antibiotic perturbation	41
The genome of a wild Medicago species provides insights into the tolerant mechanisms of legume forage to environmental stress	40
Genomic evidence for recurrent genetic admixture during the domestication of Mediterranean olive trees (Olea europaea L.)	39
The transposable element-rich genome of the cereal pest Sitophilus oryzae	39
Conventional laboratory housing increases morbidity and mortality in research rodents: results of a meta-analysis	39
Paxillin mediates ATP-induced activation of P2X7 receptor and NLRP3 inflammasome	39
Global population genetic structure and demographic trajectories of the black soldier fly, Hermetia illucens	39
Fluid shear stress enhances T cell activation through Piezo1	38
Characterization of a novel type of carbonic anhydrase that acts without metal cofactors	38
The genome sequence of the grape phylloxera provides insights into the evolution, adaptation, and invasion routes of an iconic pest	37
Towards open, reliable, and transparent ecology and evolutionary biology	36
Characterizing RNA stability genome-wide through combined analysis of PRO-seq and RNA-seq data	36
Multi-omics analysis delineates the distinct functions of sub-cellular acetyl-CoA pools in Toxoplasma gondii	35
Genome assembly of the basket willow, Salix viminalis, reveals earliest stages of sex chromosome expansion	35
Development of an efficient and precise adenine base editor (ABE) with expanded target range in allotetraploid cotton (Gossypium hirsutum)	34
Rapid protein evolution, organellar reductions, and invasive intronic elements in the marine aerobic parasite dinoflagellate Amoebophrya spp	34
Sorting and packaging of RNA into extracellular vesicles shape intracellular transcript levels	34
Comparative whole genome DNA methylation profiling across cattle tissues reveals global and tissue-specific methylation patterns	34
Stimulus-specific behavioral responses of zebrafish to a large range of odors exhibit individual variability	34
Comprehensive transcriptome and methylome analysis delineates the biological basis of hair follicle development and wool-related traits in Merino sheep	33
Gut bacterial deamination of residual levodopa medication for Parkinson’s disease	33
Impact of COVID-19 on early career scientists: an optimistic guide for the future	33
Transposon-induced epigenetic silencing in the X chromosome as a novel form of dmrt1 expression regulation during sex determination in the fighting fish	33
Measuring and modeling energy and power consumption in living microbial cells with a synthetic ATP reporter	32
Native-like membrane models of E. coli polar lipid extract shed light on the importance of lipid composition complexity	32
2000-year-old pathogen genomes reconstructed from metagenomic analysis of Egyptian mummified individuals	32
Phylogenomic approaches untangle early divergences and complex diversifications of the olive plant family	31
Articulating the “stem cell niche” paradigm through the lens of non-model aquatic invertebrates	31
Association of Bacteroides acidifaciens relative abundance with high-fibre diet-associated radiosensitisation	31
DNA methyltransferase 3a mediates developmental thermal plasticity	30
Oxidative stress mediates thalidomide-induced pain by targeting peripheral TRPA1 and central TRPV4	30
Comparative analysis of morabine grasshopper genomes reveals highly abundant transposable elements and rapidly proliferating satellite DNA repeats	29
Modelling the Wolbachia incompatible insect technique: strategies for effective mosquito population elimination	29
Gregarine single-cell transcriptomics reveals differential mitochondrial remodeling and adaptation in apicomplexans	29
A primary cell wall cellulose-dependent defense mechanism against vascular pathogens revealed by time-resolved dual transcriptomics	29
A versatile contribution of both aminopeptidases N and ABC transporters to Bt Cry1Ac toxicity in the diamondback moth	29
Epigenomics and genotype-phenotype association analyses reveal conserved genetic architecture of complex traits in cattle and human	29
LocalZProjector and DeProj: a toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images	28
Engineered sex ratio distortion by X-shredding in the global agricultural pest Ceratitis capitata	27

Deconvolution of cellular subsets in human tissue based on targeted DNA methylation analysis at individual CpG sites	27
Genomic analysis of field pennycress (Thlaspi arvense) provides insights into mechanisms of adaptation to high elevation	27
Comparative 3D genome architecture in vertebrates	27
Bioengineered human skeletal muscle capable of functional regeneration	27
A chromosome-level assembly of the cat flea genome uncovers rampant gene duplication and genome size plasticity	27
Aerodynamics and motor control of ultrasonic vocalizations for social communication in mice and rats	26
Precise base editing with CC context-specificity using engineered human APOBEC3G-nCas9 fusions	26
Satellitome comparison of two oedipodine grasshoppers highlights the contingent nature of satellite DNA evolution	26
Identification of African swine fever virus-like elements in the soft tick genome provides insights into the virus’ evolution	26
Segmentation, tracking and cell cycle analysis of live-cell imaging data with Cell-ACDC	25
TDP-43 prevents retrotransposon activation in the Drosophila motor system through regulation of Dicer-2 activity	25
Genomic architecture of endogenous ichnoviruses reveals distinct evolutionary pathways leading to virus domestication in parasitic wasps	25
Dynamic and reversible DNA methylation changes induced by genome separation and merger of polyploid wheat	25
Modeling confinement and reversibility of threshold-dependent gene drive systems in spatially-explicit Aedes aegypti populations	25
m5U-SVM: identification of RNA 5-methyluridine modification sites based on multi-view features of physicochemical features and distributed representation	25
Large-scale genomic analysis of antimicrobial resistance in the zoonotic pathogen Streptococcus suis	24
Divergent camptothecin biosynthetic pathway in Ophiorrhiza pumila	24
Symbiont transmission in marine sponges: reproduction, development, and metamorphosis	24
Stomatal conductance limited the CO2 response of grassland in the last century	24
Pathologic tau conformer ensembles induce dynamic, liquid-liquid phase separation events at the nuclear envelope	24
Monophyletic blowflies revealed by phylogenomics	24
A unified evolutionary origin for the ubiquitous protein transporters SecY and YidC	24
Wonky whales: the evolution of cranial asymmetry in cetaceans	24
Resilin matrix distribution, variability and function in Drosophila	24
Genomic history of the Italian population recapitulates key evolutionary dynamics of both Continental and Southern Europeans	24
Large-scale genomic analysis reveals the genetic cost of chicken domestication	24
Single-cell resolution landscape of equine peripheral blood mononuclear cells reveals diverse cell types including T-bet+ B cells	23
TORC1 regulates the transcriptional response to glucose and developmental cycle via the Tap42-Sit4-Rrd1/2 pathway in Saccharomyces cerevisiae	23
Genome-scale CRISPR screening at high sensitivity with an empirically designed sgRNA library	22
Single-cell RNA-seq reveals a concomitant delay in differentiation and cell cycle of aged hematopoietic stem cells	22
Aneuploidy-induced proteotoxic stress can be effectively tolerated without dosage compensation, genetic mutations, or stress responses	22
Inter-embryo gene expression variability recapitulates the hourglass pattern of evo-devo	22
Beyond Drosophila: resolving the rapid radiation of schizophoran flies with phylotranscriptomics	22
Neuronal cell-based high-throughput screen for enhancers of mitochondrial function reveals luteolin as a modulator of mitochondria-endoplasmic reticulum coupling	22
The mitochondrially-localized nucleoside diphosphate kinase D (NME4) is a novel metastasis suppressor	22
An essential vesicular-trafficking phospholipase mediates neutral lipid synthesis and contributes to hemozoin formation in Plasmodium falciparum	22
Crystal structure of the yeast heterodimeric ADAT2/3 deaminase	22
Relationship between oxygen consumption and neuronal activity in a defined neural circuit	21
A simple threat-detection strategy in mice	21
Multi-faceted analysis provides little evidence for recurrent whole-genome duplications during hexapod evolution	21
Waking experience modulates sleep need in mice	21
Large-scale transcriptomics to dissect 2 years of the life of a fungal phytopathogen interacting with its host plant	21
Effects of immune challenge on expression of life-history and immune trait expression in sexually reproducing metazoans—a meta-analysis	21
Deep learning-based behavioral profiling of rodent stroke recovery	21
Mangroves are an overlooked hotspot of insect diversity despite low plant diversity	21
Sexual conflict drives micro- and macroevolution of sexual dimorphism in immunity	20
Verticillium dahliae CFEM proteins manipulate host immunity and differentially contribute to virulence	20
LEA motifs promote desiccation tolerance in vivo	20
The genome of the zoonotic malaria parasite Plasmodium simium reveals adaptations to host switching	20
Regenerating zebrafish scales express a subset of evolutionary conserved genes involved in human skeletal disease	20
Dynamic genetic differentiation drives the widespread structural and functional convergent evolution of snake venom proteinaceous toxins	20
Short single-stranded DNAs with putative non-canonical structures comprise a new class of plasma cell-free DNA	20
Sensory adaptations reshaped intrinsic factors underlying morphological diversification in bats	20
The genome of the stable fly, Stomoxys calcitrans, reveals potential mechanisms underlying reproduction, host interactions, and novel targets for pest control	20
Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles	20
DHA alleviates diet-induced skeletal muscle fiber remodeling via FTO/m6A/DDIT4/PGC1α signaling	20
Single-cell spatial transcriptomic analysis reveals common and divergent features of developing postnatal granule cerebellar cells and medulloblastoma	20
Defining rules governing recognition and Fc-mediated effector functions to the HIV-1 co-receptor binding site	20
Mapping the past, present and future research landscape of paternal effects	20
Highly flexible metabolism of the marine euglenozoan protist Diplonema papillatum	20
Mechanical force-induced morphology changes in a human fungal pathogen	19
20E-mediated regulation of BmKr-h1 by BmKRP promotes oocyte maturation	19
Phylogenomic analysis of Syngnathidae reveals novel relationships, origins of endemic diversity and variable diversification rates	19
Spatial and temporal heterogeneity in the lineage progression of fine oligodendrocyte subtypes	19
Impact of male trait exaggeration on sex-biased gene expression and genome architecture in a water strider	19
The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice	19
MATISSE: a method for improved single cell segmentation in imaging mass cytometry	19
Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31	19
ERF49 mediates brassinosteroid regulation of heat stress tolerance in Arabidopsis thaliana	19
Time of day as a critical variable in biology	19
Both Conifer II and Gnetales are characterized by a high frequency of ancient mitochondrial gene transfer to the nuclear genome	19
Invasive snails, parasite spillback, and potential parasite spillover drive parasitic diseases of Hippopotamus amphibius in artificial lakes of Zimbabwe	18
Using spatial genetics to quantify mosquito dispersal for control programs	18
MIEF1/2 orchestrate mitochondrial dynamics through direct engagement with both the fission and fusion machineries	18
The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization	18
Innate antiviral defense demonstrates high energetic efficiency in a bony fish	18
Differing effects of size and lifestyle on bone structure in mammals	18
Spatial and temporal modulation of enterotoxigenic E. coli H10407 pathogenesis and interplay with microbiota in human gut models	18
Protein kinase A controls yeast growth in visible light	18
Circulating miRNA repertoire as a biomarker of metabolic and reproductive states in rainbow trout	18

Predicting the hosts of prokaryotic viruses using GCN-based semi-supervised learning	18
Complete representation of a tapeworm genome reveals chromosomes capped by centromeres, necessitating a dual role in segregation and protection	18
The CBP KIX domain regulates long-term memory and circadian activity	18
Genetic dissection of the mitochondrial lipoylation pathway in yeast	17
Analysis of urinary exosomal metabolites identifies cardiovascular risk signatures with added value to urine analysis	17
The pangenome of the wheat pathogen Pyrenophora tritici-repentis reveals novel transposons associated with necrotrophic effectors ToxA and ToxB	17
Integrated omics unveil the secondary metabolic landscape of a basal dinoflagellate	17
Mycobacterium leprae diversity and population dynamics in medieval Europe from novel ancient genomes	17
Ionotropic receptors in the turnip moth Agrotis segetum respond to repellent medium-chain fatty acids	17
Natural food intake patterns have little synchronizing effect on peripheral circadian clocks	17
Feedback inhibition of AMT1 NH4+-transporters mediated by CIPK15 kinase	17
Sea urchin larvae utilize light for regulating the pyloric opening	17
Ultrastructural and molecular analysis of the origin and differentiation of cells mediating brittle star skeletal regeneration	17
Apoptosis is not conserved in plants as revealed by critical examination of a model for plant apoptosis-like cell death	17
Self-organising human gonads generated by a Matrigel-based gradient system	17
Experimental infection with the hookworm, Necator americanus, is associated with stable gut microbial diversity in human volunteers with relapsing multiple sclerosis	17
Boundaries potentiate polycomb response element-mediated silencing	17
DNA methylation atlas and machinery in the developing and regenerating annelid Platynereis dumerilii	17
miR-31-5p regulates cold acclimation of the wood-boring beetle Monochamus alternatus via ascaroside signaling	17
Genomics and transcriptomics yields a system-level view of the biology of the pathogen Naegleria fowleri	17
Using a chimeric respiratory chain and EPR spectroscopy to determine the origin of semiquinone species previously assigned to mitochondrial complex I	17
Temporospatial shifts within commercial laboratory mouse gut microbiota impact experimental reproducibility	17
Phylotranscriptomics points to multiple independent origins of multicellularity and cellular differentiation in the volvocine algae	17
Single-cell DNA and RNA sequencing reveals the dynamics of intra-tumor heterogeneity in a colorectal cancer model	17
Adipoclast: a multinucleated fat-eating macrophage	17
Automated identification of the mouse brain’s spatial compartments from in situ sequencing data	16
Molecular action of larvicidal flavonoids on ecdysteroidogenic glutathione S-transferase Noppera-bo in Aedes aegypti	16
Disruption of left-right axis specification in Ciona induces molecular, cellular, and functional defects in asymmetric brain structures	16
H3K27 modifiers regulate lifespan in C. elegans in a context-dependent manner	16
Circadian rhythms in the plant host influence rhythmicity of rhizosphere microbiota	16
Nutritional control regulates symbiont proliferation and life history in coral-dinoflagellate symbiosis	16
Prediction of protein solubility based on sequence physicochemical patterns and distributed representation information with DeepSoluE	16
Vickermania gen. nov., trypanosomatids that use two joined flagella to resist midgut peristaltic flow within the fly host	16
Genome-wide annotation of protein-coding genes in pig	16
Chromosome-level genome assemblies of four wild peach species provide insights into genome evolution and genetic basis of stress resistance	16
Cotton D genome assemblies built with long-read data unveil mechanisms of centromere evolution and stress tolerance divergence	16
Some like it hot: population-specific adaptations in venom production to abiotic stressors in a widely distributed cnidarian	16
The selectivity filter of the mitochondrial protein import machinery	16
An optimized base editor with efficient C-to-T base editing in zebrafish	16
Nutritional status impacts dengue virus infection in mice	16
Developing long-term conservation priority planning for medicinal plants in China by combining conservation status with diversity hotspot analyses and climate change prediction	16
Divergent CPEB prion-like domains reveal different assembly mechanisms for a generic amyloid-like fold	16
Input from torus longitudinalis drives binocularity and spatial summation in zebrafish optic tectum	16
Fruit bats adjust their foraging strategies to urban environments to diversify their diet	16
Pancreatic and intestinal endocrine cells in zebrafish share common transcriptomic signatures and regulatory programmes	16
The Venturia inaequalis effector repertoire is dominated by expanded families with predicted structural similarity, but unrelated sequence, to avirulence proteins from other plant-pathogenic fungi	16
Engineered Cas12a-Plus nuclease enables gene editing with enhanced activity and specificity	16
A phenomics approach for antiviral drug discovery	15
Microfluidic guillotine reveals multiple timescales and mechanical modes of wound response in Stentor coeruleus	15
The relationship between sternum variation and mode of locomotion in birds	15
Lack of drug-induced post-retrieval amnesia for auditory fear memories in rats	15
A neuromechanical model for Drosophila larval crawling based on physical measurements	15
Unprecedented organelle genomic variations in morning glories reveal independent evolutionary scenarios of parasitic plants and the diversification of plant mitochondrial complexes	15
The roles of hybridization and habitat fragmentation in the evolution of Brazil’s enigmatic longwing butterflies, Heliconius nattereri and H. hermathena	15
Anaerobic derivates of mitochondria and peroxisomes in the free-living amoeba Pelomyxa schiedti revealed by single-cell genomics	15
The amygdala modulates prepulse inhibition of the auditory startle reflex through excitatory inputs to the caudal pontine reticular nucleus	15
Mutagenesis of the odorant receptor co-receptor (Orco) reveals severe olfactory defects in the crop pest moth Helicoverpa armigera	15
Mutant resources for functional genomics in Dictyostelium discoideum using REMI-seq technology	15
Asymmetric expansions of FT and TFL1 lineages characterize differential evolution of the EuPEBP family in the major angiosperm lineages	15
Genome of the pincer wasp Gonatopus flavifemur reveals unique venom evolution and a dual adaptation to parasitism and predation	15
Retargeting azithromycin analogues to have dual-modality antimalarial activity	15
The stem rust fungus Puccinia graminis f. sp. tritici induces centromeric small RNAs during late infection that are associated with genome-wide DNA methylation	15
Deviations from temporal scaling support a stage-specific regulation for C. elegans postembryonic development	15
Enhancer-promoter interaction maps provide insights into skeletal muscle-related traits in pig genome	15
Modular evolution of secretion systems and virulence plasmids in a bacterial species complex	15
Genome plasticity in Paramecium bursaria revealed by population genomics	15
Rearrangement and domestication as drivers of Rosaceae mitogenome plasticity	15
The evolutionarily conserved ESRE stress response network is activated by ROS and mitochondrial damage	15
Functional analyses of phosphatidylserine/PI(4)P exchangers with diverse lipid species and membrane contexts reveal unanticipated rules on lipid transfer	15
The dorsoanterior brain of adult amphioxus shares similarities in expression profile and neuronal composition with the vertebrate telencephalon	15
DNA interference is controlled by R-loop length in a type I-F1 CRISPR-Cas system	15
Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones	14
Current cancer driver variant predictors learn to recognize driver genes instead of functional variants	14
Single-cell transcriptomics reveals the effect of PD-L1/TGF-β blockade on the tumor microenvironment	14
The Wnt-specific astacin proteinase HAS-7 restricts head organizer formation in Hydra	14
Very long intergenic non-coding (vlinc) RNAs directly regulate multiple genes in cis and trans	14
Zinc antagonizes iron-regulation of tyrosine hydroxylase activity and dopamine production in Drosophila melanogaster	14
Mixotrophic chemosynthesis in a deep-sea anemone from hydrothermal vents in the Pescadero Basin, Gulf of California	14
Flexible and stretchable polymer optical fibers for chronic brain and vagus nerve optogenetic stimulations in free-behaving animals	14
A cell-to-patient machine learning transfer approach uncovers novel basal-like breast cancer prognostic markers amongst alternative splice variants	14
The evolution of pelvic canal shape and rotational birth in humans	14
The mutational landscape of human olfactory G protein-coupled receptors	14
Molecular drivers of insecticide resistance in the Sahelo-Sudanian populations of a major malaria vector Anopheles coluzzii	14
Malignant transformation and genetic alterations are uncoupled in early colorectal cancer progression	14
An IGF1-expressing endometrial stromal cell population is associated with human decidualization	14
Single-cell morphological characterization of CRH neurons throughout the whole mouse brain	14
Taxonomy-aware, sequence similarity ranking reliably predicts phage–host relationships	14
Practical real-time MEG-based neural interfacing with optically pumped magnetometers	14
A universal power law for modelling the growth and form of teeth, claws, horns, thorns, beaks, and shells	14
Publication bias impacts on effect size, statistical power, and magnitude (Type M) and sign (Type S) errors in ecology and evolutionary biology	14
A protocol for adding knowledge to Wikidata: aligning resources on human coronaviruses	14
Epistasis and evolution: recent advances and an outlook for prediction	14
Monkeying around with venom: an increased resistance to α-neurotoxins supports an evolutionary arms race between Afro-Asian primates and sympatric cobras	14
The gut symbiont Sphingomonas mediates imidacloprid resistance in the important agricultural insect pest Aphis gossypii Glover	14
Conservation and trans-regulation of histone modification in the A and B subgenomes of polyploid wheat during domestication and ploidy transition	13