OOIR: Observatory of International Research

Papers

(The H4-Index of Journal of Neuroinflammation is 63. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Characteristics of TSPO expression in marmoset EAE	399
Progranulin deficiency in Iba-1+ myeloid cells exacerbates choroidal neovascularization by perturbation of lysosomal function and abnormal inflammation	310
Astroglial modulation of synaptic function in the non-demyelinated cerebellar cortex is dependent on MyD88 signaling in a model of toxic demyelination	279
Inhibition of IL-6 trans-signaling promotes post-stroke functional recovery in a sex and dose-dependent manner	263
Growth differentiation factor 15 aggravates sepsis-induced cognitive and memory impairments by promoting microglial inflammatory responses and phagocytosis	223
Interleukin-2 improves insulin sensitivity through hypothalamic sympathetic activation in obese mice	182
How the gut microbiota impacts neurodegenerative diseases by modulating CNS immune cells	169
Decoding dengue’s neurological assault: insights from single-cell CNS analysis in an immunocompromised mouse model	154
Development of cerebral microhemorrhages in a mouse model of hypertension	147
Antiretroviral drug therapy does not reduce neuroinflammation in an HIV-1 infection brain organoid model	146
Alzheimer’s disease-related transcriptional sex differences in myeloid cells	145
Neuroinflammation in the anterior cingulate cortex: the potential supraspinal mechanism underlying the mirror-image pain following motor fiber injury	141
Metformin normalizes mitochondrial function to delay astrocyte senescence in a mouse model of Parkinson’s disease through Mfn2-cGAS signaling	138
D-dopachrome tautomerase activates COX2/PGE2 pathway of astrocytes to mediate inflammation following spinal cord injury	133
Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response	130
Progressive inflammation reduces high-frequency EEG activity and cortical dendritic arborisation in late gestation fetal sheep	126
Microglial C/EBPβ-Fcgr1 regulatory axis blocking inhibits microglial pyroptosis and improves neurological recovery	121
A pre-existing Toxoplasma gondii infection exacerbates the pathophysiological response and extent of brain damage after traumatic brain injury in mice	119
HIF1α-dependent hypoxia response in myeloid cells requires IRE1α	119
Spatial transcriptomics and neurofilament light chain reveal changes in lesion patterns in murine autoimmune neuroinflammation	117
The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study	110
Deletion of myeloid HDAC3 promotes efferocytosis to ameliorate retinal ischemic injury	109
Complement-membrane regulatory proteins are absent from the nodes of Ranvier in the peripheral nervous system	100
Japanese encephalitis virus-induced DNA methylation contributes to blood-brain barrier permeability by modulating tight junction protein expression	88
Carotid artery vascular stenosis causes the blood-CSF barrier damage and neuroinflammation	87

IL-7Rα on CD4+ T cells is required for their survival and the pathogenesis of experimental autoimmune encephalomyelitis	87
Interaction of high-fat diet and brain trauma alters adipose tissue macrophages and brain microglia associated with exacerbated cognitive dysfunction	83
AMPK-autophagy-mediated inhibition of microRNA-30a-5p alleviates morphine tolerance via SOCS3-dependent neuroinflammation suppression	83
Oxygen therapy attenuates neuroinflammation after spinal cord injury	83
Protein kinase B (AKT) upregulation and Thy-1-αvβ3 integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis	80
Biomass smoke inhalation promotes neuroinflammatory and metabolomic temporal changes in the hippocampus of female mice	79
Systemic inflammation following traumatic injury and its impact on neuroinflammatory gene expression in the rodent brain	79
Kinetic changes in microglia-related retinal transcripts in experimental autoimmune uveoretinitis (EAU) of B10.RIII mice	76
Mas receptor activation facilitates innate hematoma resolution and neurological recovery after hemorrhagic stroke in mice	76
Inflammatory responses revealed through HIV infection of microglia-containing cerebral organoids	76
Synaptic loss and progression in mice infected with Angiostrongylus cantonensis in the early stage	76
Thymic gene expression analysis reveals a potential link between HIF-1A and Th17/Treg imbalance in thymoma associated myasthenia gravis	73
Monocytes release cystatin F dimer to associate with Aβ and aggravate amyloid pathology and cognitive deficits in Alzheimer’s disease	72
Systemic inflammatory markers of persistent cerebral edema after aneurysmal subarachnoid hemorrhage	71
Targeted activation of ErbB4 receptor ameliorates neuronal deficits and neuroinflammation in a food-borne polystyrene microplastic exposed mouse model	71
Sex chromosomes and gonads modify microglial-mediated pathology in a mouse model of Alzheimer’s disease	70
H3K18 lactylation-mediated nucleotide-binding oligomerization domain-2 (NOD2) expression promotes bilirubin-induced pyroptosis of astrocytes	70
Inhibition of neutrophil extracellular traps alleviates blood–brain barrier disruption and cognitive dysfunction via Wnt3/β-catenin/TCF4 signaling in sepsis-associated encephalopathy	70
T cell receptor activation contributes to brain damage after intracerebral hemorrhage in mice	70
Chronic intermittent hypoxia disrupts protective microgliosis in ischemic proliferative retinopathy	70
Inhibition of histone deacetylase 6 alleviates neuropathic pain via direct regulating post-translation of spinal STAT3 and decreasing downstream C-C Motif Chemokine Ligand 7 synthesis	70
Extracellular vesicles derived from mesenchymal stem cells alleviate neuroinflammation and mechanical allodynia in interstitial cystitis rats by inhibiting NLRP3 inflammasome activation	69
The role of CD56bright NK cells in neurodegenerative disorders	69
Differential effect of an evolving amyloid and tau pathology on brain phospholipids and bioactive lipid mediators in rat models of Alzheimer-like pathology	67
PEDF-34 attenuates neurological deficit and suppresses astrocyte-dependent neuroinflammation by modulating astrocyte polarization via 67LR/JNK/STAT1 signaling pathway after subarachnoid hemorrhage in	67
Distinct features of B cell receptors in neuromyelitis optica spectrum disorder among CNS inflammatory demyelinating diseases	67
Tumor necrosis factor regulates leukocyte recruitment but not bacterial persistence during Staphylococcus aureus craniotomy infection	67
Succinate-induced macrophage polarization and RBP4 secretion promote vascular sprouting in ocular neovascularization	65
Maternal immunoglobulin G affects brain development of mouse offspring	65
Citrobacter rodentium infection impairs dopamine metabolism and exacerbates the pathology of Parkinson’s disease in mice	65
Aging triggers an upregulation of a multitude of cytokines in the male and especially the female rodent hippocampus but more discrete changes in other brain regions	65
Inducible co-stimulatory molecule (ICOS) alleviates paclitaxel-induced neuropathic pain via an IL-10-mediated mechanism in female mice	65
Prehabilitative resistance exercise reduces neuroinflammation and improves mitochondrial health in aged mice with perioperative neurocognitive disorders	65
LPA1 signaling drives Schwann cell dedifferentiation in experimental autoimmune neuritis	64
Chronic neuroinflammation during aging leads to cholinergic neurodegeneration in the mouse medial septum	64
Neuroimmune modulation in liver pathophysiology	63
Myeloid deficiency of the intrinsic clock protein BMAL1 accelerates cognitive aging by disrupting microglial synaptic pruning	63
Capsazepine decreases corneal pain syndrome in severe dry eye disease	63