Journal of Neuroinflammation

Papers
(The median citation count of Journal of Neuroinflammation is 10. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)
ArticleCitations
Maternal immunoglobulin G affects brain development of mouse offspring527
Correction: Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway478
Integrin Mac1 mediates paraquat and maneb-induced learning and memory impairments in mice through NADPH oxidase–NLRP3 inflammasome axis-dependent microglial activation281
The deficient CLEC5A ameliorates the behavioral and pathological deficits via the microglial Aβ clearance in Alzheimer’s disease mouse model243
Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response238
Inflammation in Neuronal Intranuclear Inclusion Disease (NIID): mechanisms, biomarkers, and therapeutic implications191
Clonally expanded HSP-specific T cells contribute to glaucomatous neurodegeneration via the mTORC1 pathway168
Correction to: Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress161
Citrobacter rodentium infection impairs dopamine metabolism and exacerbates the pathology of Parkinson’s disease in mice150
Inhibition of histone deacetylase 6 alleviates neuropathic pain via direct regulating post-translation of spinal STAT3 and decreasing downstream C-C Motif Chemokine Ligand 7 synthesis141
SARS-CoV-2 spike triggers TLR7-dependent endolysosome dysfunction and senescence in human astrocytes137
Phosphatidate phosphatase Lipin1 alters mitochondria-associated endoplasmic reticulum membranes (MAMs) homeostasis: effects which contribute to the development of diabetic encephalopathy136
Integrative imaging and transcriptomics implicate neutrophils in microvascular no-reflow after stroke135
Inflammatory blood-based biomarkers to aid in the assessment and prognostication of traumatic brain injury: a TRACK-TBI study131
Toxoplasma gondii drives myeloid immune cell recruitment to amyloid plaques in Alzheimer’s model mice131
The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study126
TPM1 mediates inflammation downstream of TREM2 via the PKA/CREB signaling pathway126
Neuroimmune programming of childhood trauma: comorbid mechanisms and developmental origins of depression and autoimmune diseases123
Altered phenotype and gene expression of regulatory T cells (Tregs) in children with Autism, and the relationship with comorbid gastrointestinal symptoms117
HMGB1-mediated endoplasmic reticulum stress in monocyte-derived dendritic cells regulates CD4+ T cell immune responses in myasthenia gravis117
Therapeutic intervention in neuroinflammation for neovascular ocular diseases through targeting the cGAS-STING-necroptosis pathway117
HIF1α-dependent hypoxia response in myeloid cells requires IRE1α116
Cell-intrinsic vulnerability and immune activation cooperate to drive degeneration in a mitochondrial complex I deficiency model of optic neuropathy107
Peripheral immunosuppressive and immunostimulatory signatures of severity and pain in spinal cord injury106
Intrauterine inflammation and postnatal intravenous dopamine alter the neurovascular unit in preterm newborn lambs103
Preoperative gut microbiota of POCD patients induces pre- and postoperative cognitive impairment and systemic inflammation in rats96
Gut microbiota and their influence in brain cancer milieu96
Hypothalamic arcuate microglia in sepsis: AgRP circuit engagement and ARHGAP24-dependent remodeling92
Flow cytometry identifies changes in peripheral and intrathecal lymphocyte patterns in CNS autoimmune disorders and primary CNS malignancies92
CCL5 and CD11b-fibrin interactions regulate microglia migration and morphology in hyperinflammatory experimental cerebral malaria91
Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis89
Protein kinase B (AKT) upregulation and Thy-1-αvβ3 integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis88
Fractalkine isoforms differentially regulate microglia-mediated inflammation and enhance visual function in the diabetic retina88
Tregs dysfunction aggravates postoperative cognitive impairment in aged mice85
IL-7Rα on CD4+ T cells is required for their survival and the pathogenesis of experimental autoimmune encephalomyelitis84
LXR agonism for CNS diseases: promises and challenges83
Exercise suppresses neuroinflammation for alleviating Alzheimer’s disease83
How the gut microbiota impacts neurodegenerative diseases by modulating CNS immune cells81
Carotid artery vascular stenosis causes the blood-CSF barrier damage and neuroinflammation81
Elucidating the specific mechanisms of the gut-brain axis: the short-chain fatty acids-microglia pathway80
Selective neuronal expression of progranulin is sufficient to provide neuroprotective and anti-inflammatory effects after traumatic brain injury80
HMGB1 mediates synaptic loss and cognitive impairment in an animal model of sepsis-associated encephalopathy79
Inhibition of neutrophil extracellular traps alleviates blood–brain barrier disruption and cognitive dysfunction via Wnt3/β-catenin/TCF4 signaling in sepsis-associated encephalopathy78
Extracellular vesicles produced by HIV-1 Nef-expressing cells induce myelin impairment and oligodendrocyte damage in the mouse central nervous system78
Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress77
Ubiquitination-mediated upregulation of glycolytic enzyme MCT4 in promoting astrocyte reactivity during neuroinflammation76
Single-cell RNA sequencing uncovers neutrophil clusters associated with autoimmune neuroinflammation76
H3K27me3 of Rnf19a promotes neuroinflammatory response during Japanese encephalitis virus infection75
Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease75
Lysosomal cholesteryl ester hydrolysis drives white matter repair by reprogramming microglia into a novel reparative state73
Epigenetic brain reprogramming rejuvenates neuro-immune circuits to reverse Alzheimer’s disease pathology and systemic bone loss71
Correction: Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice70
Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS69
Macrophage exosomal miR-30c-2-3p in atherosclerotic plaques aggravates microglial neuroinflammation during large-artery atherosclerotic stroke via TGF-β/SMAD2 pathway69
Supporting the differential diagnosis of connective tissue diseases with neurological involvement by blood and cerebrospinal fluid flow cytometry68
Tumor immunogenicity shapes CNS immune niches and CD8⁺ T cell fate in glioblastoma68
CRTH2 is critical for IL-1β-producing B cells during experimental autoimmune encephalomyelitis in mice via p38 signaling68
Exogenous monocyte myeloid-derived suppressor cells ameliorate immune imbalance, neuroinflammation and cognitive impairment in 5xFAD mice infected with Porphyromonas gingivalis67
Ischemic injury triggers a protective microglial phenotype in models of Aβ pathology66
Immune imbalance between T helper 1, T helper 17 and regulatory T cells fuels amyotrophic lateral sclerosis pathogenesis: disease trajectory, diagnosis and therapeutic implications65
LAPF enhances lysosomal acidification to promote TLR9 and cGAS-STING-mediated antiviral immunity and attenuate HSV-1-induced neuroinflammatory pain65
AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease65
Antigen-specific adaptive immunity in Parkinson’s disease: peripheral priming, brain-border reactivation and parenchymal injury65
α7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect64
Decoding the lung-brain axis in influenza: from pulmonary infection to central nervous system injury63
Decoding Behcet’s Uveitis: an In-depth review of pathogenesis and therapeutic advances63
Cardiac arrest triggers IL-17-mediated neuroinflammation and astrocyte polarization: insights into pathogenesis and intervention63
Single−cell transcriptomic landscape of sciatic nerve after transection injury63
Profiling the neuroimmune cascade in 3xTg-AD mice exposed to successive mild traumatic brain injuries63
Hypochlorous acid derived from microglial myeloperoxidase could mediate high-mobility group box 1 release from neurons to amplify brain damage in cerebral ischemia–reperfusion injury62
Remibrutinib (LOU064) inhibits neuroinflammation driven by B cells and myeloid cells in preclinical models of multiple sclerosis62
BMAL1-GPX3 axis in the choroid plexus mitigates Aβ pathology in an amyloid mouse model62
Biomarkers of progressive multiple sclerosis decrease following autologous hematopoietic stem cell transplantation61
Nisin a probiotic bacteriocin mitigates brain microbiome dysbiosis and Alzheimer’s disease-like neuroinflammation triggered by periodontal disease61
NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway60
Deterioration of neuroimmune homeostasis in Alzheimer’s Disease patients who survive a COVID-19 infection60
MST1 promotes microglial pyroptosis and neuroinflammation in alzheimer’s disease by regulating the novel DPP8/NLRP1/Caspase-1/GSDMD-N axis59
Chronic rapid eye movement sleep deprivation aggravates the pathogenesis of Alzheimer’s disease by decreasing brain O-GlcNAc cycling in mice59
IDO1 modulates pain sensitivity and comorbid anxiety in chronic migraine through microglial activation and synaptic pruning59
Circulating immune profiling reveals impaired monocyte states and trajectories driving immunosuppression in glioblastoma59
Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia58
Innate immune sensors and regulators at the blood brain barrier: focus on toll-like receptors and inflammasomes as mediators of neuro-immune crosstalk and inflammation58
Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells58
Diffuse traumatic brain injury induced stimulator of interferons (STING) signaling in microglia drives cortical neuroinflammation, neuronal dysfunction, and impaired cognition57
Inflammasomes at the crossroads of traumatic brain injury and post-traumatic epilepsy57
TLR4-dependent neuroinflammation mediates LPS-driven food-reward alterations during high-fat exposure57
Injection of amyloid-β to lateral ventricle induces gut microbiota dysbiosis in association with inhibition of cholinergic anti-inflammatory pathways in Alzheimer’s disease57
A systematic review of the causes and consequences of spreading depolarization in neuroinflammation; implications for neurovascular disorders57
Febrile temperature-regulated TRPV1 in CD4+ T cells mediates neuroinflammation in complex febrile seizures56
Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systems56
Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice55
Microglia TFEB activation attenuates Alzheimer’s disease pathology by enhancing autophagy-lysosomal function55
The complement system in Alzheimer’s disease: evaluating biomarker potential in a complex neuroimmune context54
APOEε4 alters ApoE and Fabp7 in frontal cortex white matter in prodromal Alzheimer's disease54
Inhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK/p-MLC pathway54
Interleukin-3 is associated with sTREM2 and mediates the correlation between amyloid-β and tau pathology in Alzheimer’s disease53
The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy53
Neuro-immune regulation of sepsis-associated delirium via the PBN-CeA-spleen axis53
Morinda officinalis oligosaccharides mitigate depression-like behaviors in hypertension rats by regulating Mfn2-mediated mitophagy52
Tryptophan-rich diet and its effects on Htr7+ Tregs in alleviating neuroinflammation and cognitive impairment induced by lipopolysaccharide52
Brd4 expression in CD4 T cells and in microglia promotes neuroinflammation in experimental autoimmune encephalomyelitis52
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats51
Salt-sensitive hypertension promotes neuronal mitochondrial stress and neurodegenerative alterations via neuro-vascular metabolic reprogramming and local RAS signaling51
Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephalomyelitis51
Irisin-integrin αV/β5 coupling of α-synuclein phagocytosis and clearance50
Complement inhibition targets a rich-club within the neuroinflammatory network after stroke to improve radiographic and functional outcomes50
Traumatic brain injury alters the effects of class II invariant peptide (CLIP) antagonism on chronic meningeal CLIP + B cells, neuropathology, and neurobehavioral impairment in 5xFAD mice50
Sex-associated and disease state-dependent monocyte polarization and CNS-trafficking phenotypes in pediatric acute-onset neuropsychiatric syndrome (PANS)50
GAS6 as a potential target to alleviate neuroinflammation during Japanese encephalitis in mouse models50
Sex differences on laser-induced choroidal neovascularization and short-chain fatty acid treatment in a mouse model50
TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterio49
C1q-CD44 interactions regulate microglial phagocytosis, proliferation, and migration49
Unknotting the crosstalk between COPD and neuroinflammation49
Mitochondrial DNA leakage: underlying mechanisms and therapeutic implications in neurological disorders48
Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model48
SGK1-mediated deficits in microglial phagocytosis drive pathological progression in amyotrophic lateral sclerosis48
Prolactin deficiency drives diabetes-associated cognitive dysfunction by inducing microglia-mediated synaptic loss48
Border-associated macrophages: an emerging perspective from physiological basis and multi-disease roles to the mechanism of vascular cognitive impairment and dementia47
The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage46
Nanozymes in neuropathic pain: strategies bridging oxidative stress, mitochondrial repair, and neuroimmune modulation for targeted therapy46
The interaction between central and peripheral immune systems in methamphetamine use disorder: current status and future directions46
Integration of National Health Insurance claims data and animal models reveals fexofenadine as a promising repurposed drug for Parkinson’s disease46
Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer’s disease46
Repurposing of epalrestat for neuroprotection in parkinson’s disease via activation of the KEAP1/Nrf2 pathway46
Exploratory analysis of a Novel RACK1 mutation and its potential role in epileptic seizures via Microglia activation46
Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function46
Spatiotemporal dynamic changes of meningeal microenvironment influence meningeal lymphatic function following subarachnoid hemorrhage: from inflammatory response to tissue remodeling46
Satellite microglia: marker of traumatic brain injury and regulator of neuronal excitability46
Extended interval dosing of ocrelizumab modifies the repopulation of B cells without altering the clinical efficacy in multiple sclerosis45
Pathological mechanisms of motor dysfunction in familial Danish dementia: insights from a knock-in rat model44
Retraction Note: Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage44
Correction: Longitudinal accumulation of glial activation measured by TSPO-PET predicts later brain atrophy in multiple sclerosis44
An AGS-associated mutation in ADAR1 catalytic domain results in early-onset and MDA5-dependent encephalopathy with IFN pathway activation in the brain44
Retraction Note to: Regulation of autophagy by the nuclear factor κB signaling pathway in the hippocampus of rats with sepsis44
The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice43
Therapeutic reduction of neurocan in murine intracerebral hemorrhage lesions promotes oligodendrogenesis and functional recovery43
Neuroprotective effects of GSK-343 in an in vivo model of MPTP-induced nigrostriatal degeneration43
Development of a humanized anti-fibrin monoclonal antibody for the treatment of neuroinflammatory and retinal diseases43
Natural killer cell reduction and dysfunction define a pathogenic and diagnostic axis in neuromyelitis optica spectrum disorder43
Targeting microglial C1q alleviates blood–brain barrier disruption in the thalamus after cortical infarction43
Integrated omics reveal the effects of vitamin D deficiency on gut microbiota and plasma metabolism in experimental autoimmune uveitis43
Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury42
Noninvasive ultrasound stimulation to treat myocarditis through splenic neuro-immune regulation42
Glioblastoma radiomics can delineate systemic immune activity states like blood abundance of T cell populations or transcription factors42
Cinnamaldehyde and its combination with deferoxamine ameliorate inflammation, ferroptosis and hematoma expansion after intracerebral hemorrhage in mice42
Impact of disease-modifying therapy on dendritic cells and exploring their immunotherapeutic potential in multiple sclerosis42
FADS1 contributes to anesthesia/surgery-induced cognitive impairment by aggravating omega-6 fatty acid metabolic disruption in aged mice42
Mechanical regulation of microenvironment remodeling in brain tumors: from mechanism to therapy41
Proteomic profiling identifies novel inflammation-related plasma proteins associated with ischemic stroke outcome41
Fenebrutinib, a Bruton’s tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways41
Transfer of patient’s peripheral blood mononuclear cells (PBMCs) disrupts blood–brain barrier and induces anti-NMDAR encephalitis: a study of novel humanized PBMC mouse model40
Neuroinflammatory transcriptional programs induced in rhesus pre-frontal cortex white matter during acute SHIV infection40
Soluble CD27 is an intrathecal biomarker of T-cell-mediated lesion activity in multiple sclerosis40
FGF13 alleviates astrocytic apoptosis via JIP2 inhibition in the hippocampus and mitigates depression-like behavior40
Tertiary lymphoid structures in neuroinflammation coordinate neuroimmune homeostasis and pathological progression40
Astrocytic stress response is induced by exposure to astrocyte-binding antibodies expressed by plasmablasts from pediatric patients with acute transverse myelitis40
The insular cortex is not insular in thyroid eye disease: neuroimaging revelations of central–peripheral system interaction40
Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson’s disease40
Ogt-mediated O-GlcNAcylation inhibits astrocytes activation through modulating NF-κB signaling pathway39
Asrij/OCIAD1 depletion reduces inflammatory microglial activation and ameliorates Aβ pathology in an Alzheimer’s disease mouse model39
Single-cell RNA sequencing reveals a landscape and targeted treatment of ferroptosis in retinal ischemia/reperfusion injury39
A central role for fibrinogen in promoting microglial repair of the hypoxia-disrupted blood-brain barrier39
Intestinal γδ T17–IL-17A signaling disrupts hippocampal mitophagy in stress-induced depression and is restored by arketamine39
25-Hydroxycholesterol modulates microglial function and exacerbates Alzheimer’s disease pathology: mechanistic insights and therapeutic potential of cholesterol esterification inhibition39
Modular inflammation network discovery from large-scale phenotypic screening in genetically heterogeneous mouse brains38
Microglia-derived APOE2 improves remyelination even in the presence of endogenous APOE438
Glymphatic dysfunction contributes to thalamic iron retention and secondary thalamic injury after stroke: evidence from primates and rodents38
Sublytic pyroptosis blocks Schwann cell remyelination through caspase-1-mediated Tyro3 cleavage38
Endothelial-specific Ezh2 deficiency exacerbates blood-brain barrier dysfunction and neuroinflammation in sepsis-associated encephalopathy38
Ethanol-activated microglial exosomes induce MCP1 signaling mediated death of stress-regulatory proopiomelanocortin neurons in the developing hypothalamus38
SRGN amplifies microglia-mediated neuroinflammation and exacerbates ischemic brain injury38
Erythrocyte–brain endothelial interactions induce microglial responses and cerebral microhemorrhages in vivo38
[18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data38
Transcriptome alterations in peripheral blood B cells of patients with multiple sclerosis receiving immune reconstitution therapy38
Temporal changes in regulatory T cell subsets defined by the transcription factor Helios in stroke and their potential role in stroke-associated infection: a prospective case–control study38
Impairment of neuronal tyrosine phosphatase STEP worsens post-ischemic inflammation and brain injury under hypertensive condition38
IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection37
Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors37
The contribution of the meningeal immune interface to neuroinflammation in traumatic brain injury37
Sitagliptin eye drops prevent the impairment of retinal neurovascular unit in the new Trpv2+/− rat model37
PARP9 exacerbates apoptosis and neuroinflammation via the PI3K pathway in the thalamus and hippocampus and cognitive decline after cortical infarction37
Soluble CSF1R promotes microglial activation and amyloid clearance in alzheimer’s disease37
Type I/type III IFN and related factors regulate JEV infection and BBB endothelial integrity37
MAVS signaling shapes microglia responses to neurotropic virus infection37
Impaired membrane lipids in ischemic stroke: a key player in inflammation and thrombosis36
Fidgetin-like 2 knockdown increases acute neuroinflammation and improves recovery in a rat model of spinal cord injury36
LARP7 protects against ischemic brain injury by modulating NLRP3 deacetylation to suppress neuronal pyroptosis36
Inflammation-induced lysosomal dysfunction in human iPSC-derived microglia is exacerbated by APOE 4/4 genotype36
Interferon-induced GTP-binding protein MX1 drives hyperexcitability in peripheral nerves: a novel mechanism in small fiber neuropathy36
Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies36
Cyanidin-3-O-glucoside protects the brain and improves cognitive function in APPswe/PS1ΔE9 transgenic mice model36
Metabolic reprogramming via SIRT2-deficient microglial large extracellular vesicles ameliorates alzheimer’s pathology36
Circulatory extracellular vesicles transport complement C1q for promoting neuronal amyloid-β production in Alzheimer’s disease35
Temporally resolved single-cell RNA sequencing reveals protective and pathological responses during herpes simplex virus CNS infection35
Transcriptomic analysis unveils bona fide molecular signatures of microglia under conditions of homeostasis and viral encephalitis35
25-hydroxycholesterol promotes brain cytokine production and leukocyte infiltration in a mouse model of lipopolysaccharide-induced neuroinflammation35
Targeting neuroinflammation as a preventive and therapeutic approach for perioperative neurocognitive disorders35
Supraphysiologic doses of 17β-estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism35
Upregulated astrocytic HDAC7 induces depression-like disorders via deacetylating PINK1 and inhibiting mitophagy34
Copine-5-IgG-related autoimmune encephalitis: a novel paraneoplastic neurological syndrome with a strong melanoma association34
Sigma-1 receptor regulates HIV-1 and methamphetamine-induced endothelial/pericyte barrier impairment via strain-specific inflammatory responses and mitochondrial dysregulation34
Immune subversion by Leishmania infantum parasites suppresses NLRP3-driven inflammatory responses in amyloid-β-activated microglia34
Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease34
Molecular mechanisms and therapeutic potential of tryptophan metabolism in gut-brain signaling transduction: a narrative review34
Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis34
Role of myeloid cells in ischemic retinopathies: recent advances and unanswered questions34
AAV-mediated delivery of a proliferation inducing ligand (APRIL) to cortical neurons limits inflammation and demyelination in the corpus callosum of the cuprizone mouse model34
Microglia sustain anterior cingulate cortex neuronal hyperactivity in nicotine-induced pain34
Bone marrow–derived emergency monopoiesis drives brain–lung axis injury after traumatic brain injury via IL-134
Impaired response of blood neutrophils to cell-death stimulus differentiates AQP4-IgG-seropositive NMOSD from MOGAD34
Ambient RNAs removal of cortex-specific snRNA-seq reveals Apoe+ microglia/macrophage after deeper cerebral hypoperfusion in mice34
The novel HS-mimetic, Tet-29, regulates immune cell trafficking across barriers of the CNS during inflammation33
CAR T cells as novel therapeutic strategy for multiple sclerosis and other neuroimmune disorders33
Transcriptional and neuroprotective effects of hexokinase-2 inhibitors administered after stroke33
Microglia and Immune cells interactions in multiple sclerosis cognitive impairment: a postmortem study33
DNA methylation regulation of CYP450-lipid metabolism by high-altitude hypoxia: linking neuroinflammation to cognitive impairment33
P2X7-CaMKII drives 5-LOX nuclear translocation to impair microglial function after subarachnoid hemorrhage33
Moss-derived human complement factor H modulates retinal immune response and attenuates retinal degeneration33
Loss of astrocytic Bmal1 promotes blood-brain barrier disruption and synaptic dysfunction during systemic inflammation33
N-acetylglucosamine inhibits inflammation and neurodegeneration markers in multiple sclerosis: a mechanistic trial33
Interleukin-9 protects from microglia- and TNF-mediated synaptotoxicity in experimental multiple sclerosis33
Plasma proteome in LGI-1 autoimmune encephalitis32
P2X7 receptor antagonists modulate experimental autoimmune neuritis via regulation of NLRP3 inflammasome activation and Th17 and Th1 cell differentiation32
Deletion of CD47 from Schwann cells and macrophages hastens myelin disruption/dismantling and scavenging in Schwann cells and augments myelin debris phagocytosis in macrophages32
Integrated single-cell transcriptomics of cerebrospinal fluid cells in treatment-naïve multiple sclerosis32
RiboTag-based RNA profiling uncovers oligodendroglial lineage-specific inflammation in autoimmune encephalomyelitis: implications for pathogenesis32
Liver-nervous system axis: pathways, dysregulation, and translational perspectives32
Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer’s disease32
Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis32
Fascin-1 limits myosin activity in microglia to control mechanical characterization of the injured spinal cord32
Up-regulated succinylation modifications induce a senescence phenotype in microglia by altering mitochondrial energy metabolism32
Neuroimmune proteins can differentiate between tauopathies32
Differential contribution of THIK-1 K+ channels and P2X7 receptors to ATP-mediated neuroinflammation by human microglia32
Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina31
Hypothalamic kisspeptin alleviates myasthenia gravis by regulating Th1/Th17/Treg balance through Inhibition of NF-κB signaling pathway31
Retraction Note: Neuroprotective effects of the Immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity31
Distinct features of B cell receptors in neuromyelitis optica spectrum disorder among CNS inflammatory demyelinating diseases31
Repeated head impacts establish a senescent cranial bone marrow niche that impairs brain metabolism31
Repeated LPS induces training and tolerance of microglial responses across brain regions31
Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease31
Infiltrating myeloid cell-derived properdin markedly promotes microglia-mediated neuroinflammation after ischemic stroke31
Neuronal toll-like receptor-4 regulation of matrix metalloproteinase-9 activity mediates dentate circuit dysfunction after traumatic brain injury31
LncBADR promotes T cell-mediated autoimmunity by binding Mccc1 and Pcca to regulate BCAAs degradation31
Characterizing CSF inflammatory proteomics in pediatric post-hemorrhagic hydrocephalus and Anti-NMDAR encephalitis31
Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alzheimer’s disease mice31
The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity31
Interleukin-2 improves insulin sensitivity through hypothalamic sympathetic activation in obese mice31
Tumor necrosis factor regulates leukocyte recruitment but not bacterial persistence during Staphylococcus aureus craniotomy infection31
Inhibition of NADPH oxidase 2 enhances resistance to viral neuroinflammation by facilitating M1-polarization of macrophages at the extraneural tissues30
Neuroimmune modulation in liver pathophysiology30
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