Journal of Neuroinflammation

Papers
(The TQCC of Journal of Neuroinflammation is 25. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
Intrauterine inflammation and postnatal intravenous dopamine alter the neurovascular unit in preterm newborn lambs476
Maternal immunoglobulin G affects brain development of mouse offspring464
Citrobacter rodentium infection impairs dopamine metabolism and exacerbates the pathology of Parkinson’s disease in mice402
SARS-CoV-2 spike triggers TLR7-dependent endolysosome dysfunction and senescence in human astrocytes289
Integrative imaging and transcriptomics implicate neutrophils in microvascular no-reflow after stroke237
Hypothalamic arcuate microglia in sepsis: AgRP circuit engagement and ARHGAP24-dependent remodeling230
Altered phenotype and gene expression of regulatory T cells (Tregs) in children with Autism, and the relationship with comorbid gastrointestinal symptoms217
Correction to: Vagus nerve stimulation modulates hippocampal inflammation caused by continuous stress in rats202
Correction: Smek1 deficiency exacerbates experimental autoimmune encephalomyelitis by activating proinflammatory microglia and suppressing the IDO1-AhR pathway199
Extracellular vesicles produced by HIV-1 Nef-expressing cells induce myelin impairment and oligodendrocyte damage in the mouse central nervous system184
Integrin Mac1 mediates paraquat and maneb-induced learning and memory impairments in mice through NADPH oxidase–NLRP3 inflammasome axis-dependent microglial activation169
Microglia-derived exosomes modulate myelin regeneration via miR-615-5p/MYRF axis142
IL-7Rα on CD4+ T cells is required for their survival and the pathogenesis of experimental autoimmune encephalomyelitis137
Protein kinase B (AKT) upregulation and Thy-1-αvβ3 integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis132
Toxoplasma gondii drives myeloid immune cell recruitment to amyloid plaques in Alzheimer’s model mice129
Correction to: Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress126
Cell-intrinsic vulnerability and immune activation cooperate to drive degeneration in a mitochondrial complex I deficiency model of optic neuropathy124
Peripheral immunosuppressive and immunostimulatory signatures of severity and pain in spinal cord injury124
Carotid artery vascular stenosis causes the blood-CSF barrier damage and neuroinflammation123
Inflammation in Neuronal Intranuclear Inclusion Disease (NIID): mechanisms, biomarkers, and therapeutic implications121
Clonally expanded HSP-specific T cells contribute to glaucomatous neurodegeneration via the mTORC1 pathway116
Preoperative gut microbiota of POCD patients induces pre- and postoperative cognitive impairment and systemic inflammation in rats115
Flow cytometry identifies changes in peripheral and intrathecal lymphocyte patterns in CNS autoimmune disorders and primary CNS malignancies110
Gut microbiota and their influence in brain cancer milieu110
HIF1α-dependent hypoxia response in myeloid cells requires IRE1α110
Zika virus infection of mature neurons from immunocompetent mice generates a disease-associated microglia and a tauopathy-like phenotype in link with a delayed interferon beta response109
The deficient CLEC5A ameliorates the behavioral and pathological deficits via the microglial Aβ clearance in Alzheimer’s disease mouse model109
Neuroimmune programming of childhood trauma: comorbid mechanisms and developmental origins of depression and autoimmune diseases109
Fractalkine isoforms differentially regulate microglia-mediated inflammation and enhance visual function in the diabetic retina106
Therapeutic intervention in neuroinflammation for neovascular ocular diseases through targeting the cGAS-STING-necroptosis pathway105
Selective neuronal expression of progranulin is sufficient to provide neuroprotective and anti-inflammatory effects after traumatic brain injury105
LXR agonism for CNS diseases: promises and challenges101
Tregs dysfunction aggravates postoperative cognitive impairment in aged mice97
HMGB1 mediates synaptic loss and cognitive impairment in an animal model of sepsis-associated encephalopathy97
Phosphatidate phosphatase Lipin1 alters mitochondria-associated endoplasmic reticulum membranes (MAMs) homeostasis: effects which contribute to the development of diabetic encephalopathy97
How the gut microbiota impacts neurodegenerative diseases by modulating CNS immune cells94
The associations between plasma soluble Trem1 and neurological diseases: a Mendelian randomization study94
Elucidating the specific mechanisms of the gut-brain axis: the short-chain fatty acids-microglia pathway87
Inhibition of histone deacetylase 6 alleviates neuropathic pain via direct regulating post-translation of spinal STAT3 and decreasing downstream C-C Motif Chemokine Ligand 7 synthesis86
Inhibition of neutrophil extracellular traps alleviates blood–brain barrier disruption and cognitive dysfunction via Wnt3/β-catenin/TCF4 signaling in sepsis-associated encephalopathy84
Exercise suppresses neuroinflammation for alleviating Alzheimer’s disease81
TPM1 mediates inflammation downstream of TREM2 via the PKA/CREB signaling pathway81
Nanoparticulate MgH2 ameliorates anxiety/depression-like behaviors in a mouse model of multiple sclerosis by regulating microglial polarization and oxidative stress81
NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway80
Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS78
Immune imbalance between T helper 1, T helper 17 and regulatory T cells fuels amyotrophic lateral sclerosis pathogenesis: disease trajectory, diagnosis and therapeutic implications78
Exogenous monocyte myeloid-derived suppressor cells ameliorate immune imbalance, neuroinflammation and cognitive impairment in 5xFAD mice infected with Porphyromonas gingivalis77
Profiling the neuroimmune cascade in 3xTg-AD mice exposed to successive mild traumatic brain injuries77
Single−cell transcriptomic landscape of sciatic nerve after transection injury77
Chronic rapid eye movement sleep deprivation aggravates the pathogenesis of Alzheimer’s disease by decreasing brain O-GlcNAc cycling in mice77
CRTH2 is critical for IL-1β-producing B cells during experimental autoimmune encephalomyelitis in mice via p38 signaling76
Immunotherapy with an antibody against CD1d modulates neuroinflammation in an α-synuclein transgenic model of Lewy body like disease75
Supporting the differential diagnosis of connective tissue diseases with neurological involvement by blood and cerebrospinal fluid flow cytometry73
Correction: Hydrogen sulfide-releasing cyclooxygenase inhibitor ATB-346 enhances motor function and reduces cortical lesion volume following traumatic brain injury in mice72
AIBP controls TLR4 inflammarafts and mitochondrial dysfunction in a mouse model of Alzheimer’s disease72
A systematic review of the causes and consequences of spreading depolarization in neuroinflammation; implications for neurovascular disorders72
Tumor immunogenicity shapes CNS immune niches and CD8⁺ T cell fate in glioblastoma71
Injection of amyloid-β to lateral ventricle induces gut microbiota dysbiosis in association with inhibition of cholinergic anti-inflammatory pathways in Alzheimer’s disease70
Single-cell RNA sequencing reveals peripheral blood leukocyte responses to spinal cord injury in mice with humanised immune systems70
Lysosomal cholesteryl ester hydrolysis drives white matter repair by reprogramming microglia into a novel reparative state70
BMAL1-GPX3 axis in the choroid plexus mitigates Aβ pathology in an amyloid mouse model70
Deterioration of neuroimmune homeostasis in Alzheimer’s Disease patients who survive a COVID-19 infection69
Biomarkers of progressive multiple sclerosis decrease following autologous hematopoietic stem cell transplantation69
Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells68
TLR4-dependent neuroinflammation mediates LPS-driven food-reward alterations during high-fat exposure68
Diffuse traumatic brain injury induced stimulator of interferons (STING) signaling in microglia drives cortical neuroinflammation, neuronal dysfunction, and impaired cognition67
H3K27me3 of Rnf19a promotes neuroinflammatory response during Japanese encephalitis virus infection67
Macrophage exosomal miR-30c-2-3p in atherosclerotic plaques aggravates microglial neuroinflammation during large-artery atherosclerotic stroke via TGF-β/SMAD2 pathway67
Hypochlorous acid derived from microglial myeloperoxidase could mediate high-mobility group box 1 release from neurons to amplify brain damage in cerebral ischemia–reperfusion injury66
MST1 promotes microglial pyroptosis and neuroinflammation in alzheimer’s disease by regulating the novel DPP8/NLRP1/Caspase-1/GSDMD-N axis65
Nisin a probiotic bacteriocin mitigates brain microbiome dysbiosis and Alzheimer’s disease-like neuroinflammation triggered by periodontal disease64
Single-cell RNA sequencing uncovers neutrophil clusters associated with autoimmune neuroinflammation63
Ubiquitination-mediated upregulation of glycolytic enzyme MCT4 in promoting astrocyte reactivity during neuroinflammation63
Inflammasomes at the crossroads of traumatic brain injury and post-traumatic epilepsy63
Innate immune sensors and regulators at the blood brain barrier: focus on toll-like receptors and inflammasomes as mediators of neuro-immune crosstalk and inflammation63
Compromised endothelial Wnt/β-catenin signaling mediates the blood-brain barrier disruption and leads to neuroinflammation in endotoxemia61
Cardiac arrest triggers IL-17-mediated neuroinflammation and astrocyte polarization: insights into pathogenesis and intervention61
Remibrutinib (LOU064) inhibits neuroinflammation driven by B cells and myeloid cells in preclinical models of multiple sclerosis61
Decoding Behcet’s Uveitis: an In-depth review of pathogenesis and therapeutic advances61
α7 Nicotinic acetylcholine receptor: a key receptor in the cholinergic anti-inflammatory pathway exerting an antidepressant effect60
IDO1 modulates pain sensitivity and comorbid anxiety in chronic migraine through microglial activation and synaptic pruning60
Salt-sensitive hypertension promotes neuronal mitochondrial stress and neurodegenerative alterations via neuro-vascular metabolic reprogramming and local RAS signaling59
Sex differences on laser-induced choroidal neovascularization and short-chain fatty acid treatment in a mouse model59
The interaction between central and peripheral immune systems in methamphetamine use disorder: current status and future directions59
Unknotting the crosstalk between COPD and neuroinflammation58
GAS6 as a potential target to alleviate neuroinflammation during Japanese encephalitis in mouse models56
Sex-associated and disease state-dependent monocyte polarization and CNS-trafficking phenotypes in pediatric acute-onset neuropsychiatric syndrome (PANS)56
Complement inhibition targets a rich-club within the neuroinflammatory network after stroke to improve radiographic and functional outcomes56
APOEε4 alters ApoE and Fabp7 in frontal cortex white matter in prodromal Alzheimer's disease55
Inhibition of UTX/KDM6A improves recovery of spinal cord injury by attenuating BSCB permeability and macrophage infiltration through the MLCK/p-MLC pathway55
TYROBP/DAP12 knockout in Huntington’s disease Q175 mice cell-autonomously decreases microglial expression of disease-associated genes and non-cell-autonomously mitigates astrogliosis and motor deterio55
Satellite microglia: marker of traumatic brain injury and regulator of neuronal excitability55
Hepcidin deficiency impairs hippocampal neurogenesis and mediates brain atrophy and memory decline in mice55
Microglia TFEB activation attenuates Alzheimer’s disease pathology by enhancing autophagy-lysosomal function55
Tryptophan-rich diet and its effects on Htr7+ Tregs in alleviating neuroinflammation and cognitive impairment induced by lipopolysaccharide54
Neuro-immune regulation of sepsis-associated delirium via the PBN-CeA-spleen axis54
Exploratory analysis of a Novel RACK1 mutation and its potential role in epileptic seizures via Microglia activation54
Integration of National Health Insurance claims data and animal models reveals fexofenadine as a promising repurposed drug for Parkinson’s disease54
Interleukin-3 is associated with sTREM2 and mediates the correlation between amyloid-β and tau pathology in Alzheimer’s disease53
Spatiotemporal dynamic changes of meningeal microenvironment influence meningeal lymphatic function following subarachnoid hemorrhage: from inflammatory response to tissue remodeling52
Mitochondrial DNA leakage: underlying mechanisms and therapeutic implications in neurological disorders52
The BET PROTAC inhibitor dBET6 protects against retinal degeneration and inhibits the cGAS-STING in response to light damage52
Pericytes are protective in experimental pneumococcal meningitis through regulating leukocyte infiltration and blood–brain barrier function51
Border-associated macrophages: an emerging perspective from physiological basis and multi-disease roles to the mechanism of vascular cognitive impairment and dementia51
Brd4 expression in CD4 T cells and in microglia promotes neuroinflammation in experimental autoimmune encephalomyelitis51
The multifaceted role of vitreous hyalocytes: Orchestrating inflammation, angiomodulation and erythrophagocytosis in proliferative diabetic retinopathy51
Febrile temperature-regulated TRPV1 in CD4+ T cells mediates neuroinflammation in complex febrile seizures51
Traumatic brain injury alters the effects of class II invariant peptide (CLIP) antagonism on chronic meningeal CLIP + B cells, neuropathology, and neurobehavioral impairment in 5xFAD mice51
Repurposing of epalrestat for neuroprotection in parkinson’s disease via activation of the KEAP1/Nrf2 pathway50
Prolactin deficiency drives diabetes-associated cognitive dysfunction by inducing microglia-mediated synaptic loss50
Dimethyl fumarate improves cognitive impairment and neuroinflammation in mice with Alzheimer’s disease50
Cladribine treatment improves cortical network functionality in a mouse model of autoimmune encephalomyelitis50
Extracellular vesicles from mesenchymal stem cells reduce neuroinflammation in hippocampus and restore cognitive function in hyperammonemic rats50
Development of a humanized anti-fibrin monoclonal antibody for the treatment of neuroinflammatory and retinal diseases49
Human PMSCs-derived small extracellular vesicles alleviate neuropathic pain through miR-26a-5p/Wnt5a in SNI mice model49
Pathological mechanisms of motor dysfunction in familial Danish dementia: insights from a knock-in rat model49
Nanozymes in neuropathic pain: strategies bridging oxidative stress, mitochondrial repair, and neuroimmune modulation for targeted therapy49
Microglial–oligodendrocyte interactions in myelination and neurological function recovery after traumatic brain injury49
Morinda officinalis oligosaccharides mitigate depression-like behaviors in hypertension rats by regulating Mfn2-mediated mitophagy49
Extended interval dosing of ocrelizumab modifies the repopulation of B cells without altering the clinical efficacy in multiple sclerosis48
25-Hydroxycholesterol modulates microglial function and exacerbates Alzheimer’s disease pathology: mechanistic insights and therapeutic potential of cholesterol esterification inhibition48
An AGS-associated mutation in ADAR1 catalytic domain results in early-onset and MDA5-dependent encephalopathy with IFN pathway activation in the brain48
Intestinal γδ T17–IL-17A signaling disrupts hippocampal mitophagy in stress-induced depression and is restored by arketamine47
[18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data47
Astrocytic stress response is induced by exposure to astrocyte-binding antibodies expressed by plasmablasts from pediatric patients with acute transverse myelitis47
Natural killer cell reduction and dysfunction define a pathogenic and diagnostic axis in neuromyelitis optica spectrum disorder47
Retraction Note to: Regulation of autophagy by the nuclear factor κB signaling pathway in the hippocampus of rats with sepsis47
Correction: Longitudinal accumulation of glial activation measured by TSPO-PET predicts later brain atrophy in multiple sclerosis47
Retraction Note: Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage47
Fenebrutinib, a Bruton’s tyrosine kinase inhibitor, blocks distinct human microglial signaling pathways47
The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice47
Neuroprotective effects of GSK-343 in an in vivo model of MPTP-induced nigrostriatal degeneration47
Impact of disease-modifying therapy on dendritic cells and exploring their immunotherapeutic potential in multiple sclerosis47
Integrated omics reveal the effects of vitamin D deficiency on gut microbiota and plasma metabolism in experimental autoimmune uveitis47
Ogt-mediated O-GlcNAcylation inhibits astrocytes activation through modulating NF-κB signaling pathway46
Asrij/OCIAD1 depletion reduces inflammatory microglial activation and ameliorates Aβ pathology in an Alzheimer’s disease mouse model46
Noninvasive ultrasound stimulation to treat myocarditis through splenic neuro-immune regulation46
Soluble CD27 is an intrathecal biomarker of T-cell-mediated lesion activity in multiple sclerosis46
A central role for fibrinogen in promoting microglial repair of the hypoxia-disrupted blood-brain barrier45
Transient post-operative overexpression of CXCR2 on monocytes of traumatic brain injury patients drives monocyte chemotaxis toward cerebrospinal fluid and enhances monocyte-mediated immunogenic cell d45
FADS1 contributes to anesthesia/surgery-induced cognitive impairment by aggravating omega-6 fatty acid metabolic disruption in aged mice45
Neuroinflammatory transcriptional programs induced in rhesus pre-frontal cortex white matter during acute SHIV infection45
Targeting microglial C1q alleviates blood–brain barrier disruption in the thalamus after cortical infarction44
Proteomic profiling identifies novel inflammation-related plasma proteins associated with ischemic stroke outcome44
Therapeutic reduction of neurocan in murine intracerebral hemorrhage lesions promotes oligodendrogenesis and functional recovery43
Transfer of patient’s peripheral blood mononuclear cells (PBMCs) disrupts blood–brain barrier and induces anti-NMDAR encephalitis: a study of novel humanized PBMC mouse model43
SRGN amplifies microglia-mediated neuroinflammation and exacerbates ischemic brain injury43
Glioblastoma radiomics can delineate systemic immune activity states like blood abundance of T cell populations or transcription factors43
The insular cortex is not insular in thyroid eye disease: neuroimaging revelations of central–peripheral system interaction43
Cinnamaldehyde and its combination with deferoxamine ameliorate inflammation, ferroptosis and hematoma expansion after intracerebral hemorrhage in mice42
Single-cell RNA sequencing reveals a landscape and targeted treatment of ferroptosis in retinal ischemia/reperfusion injury42
Modular inflammation network discovery from large-scale phenotypic screening in genetically heterogeneous mouse brains42
Inflammasome inhibition protects dopaminergic neurons from α-synuclein pathology in a model of progressive Parkinson’s disease42
The contribution of the meningeal immune interface to neuroinflammation in traumatic brain injury41
Interferon-induced GTP-binding protein MX1 drives hyperexcitability in peripheral nerves: a novel mechanism in small fiber neuropathy41
Fidgetin-like 2 knockdown increases acute neuroinflammation and improves recovery in a rat model of spinal cord injury41
Circulatory extracellular vesicles transport complement C1q for promoting neuronal amyloid-β production in Alzheimer’s disease41
Erythrocyte–brain endothelial interactions induce microglial responses and cerebral microhemorrhages in vivo41
Ethanol-activated microglial exosomes induce MCP1 signaling mediated death of stress-regulatory proopiomelanocortin neurons in the developing hypothalamus41
Reduced microglia activation following metformin administration or microglia ablation is sufficient to prevent functional deficits in a mouse model of neonatal stroke41
Endothelial-specific Ezh2 deficiency exacerbates blood-brain barrier dysfunction and neuroinflammation in sepsis-associated encephalopathy40
Transcriptome alterations in peripheral blood B cells of patients with multiple sclerosis receiving immune reconstitution therapy40
Impaired membrane lipids in ischemic stroke: a key player in inflammation and thrombosis40
PARP9 exacerbates apoptosis and neuroinflammation via the PI3K pathway in the thalamus and hippocampus and cognitive decline after cortical infarction40
Targeting neuroinflammation as a preventive and therapeutic approach for perioperative neurocognitive disorders40
Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors40
Microglia-derived APOE2 improves remyelination even in the presence of endogenous APOE439
Sitagliptin eye drops prevent the impairment of retinal neurovascular unit in the new Trpv2+/− rat model39
Cyanidin-3-O-glucoside protects the brain and improves cognitive function in APPswe/PS1ΔE9 transgenic mice model39
25-hydroxycholesterol promotes brain cytokine production and leukocyte infiltration in a mouse model of lipopolysaccharide-induced neuroinflammation39
Molecular mechanisms and therapeutic potential of tryptophan metabolism in gut-brain signaling transduction: a narrative review39
LARP7 protects against ischemic brain injury by modulating NLRP3 deacetylation to suppress neuronal pyroptosis39
Impaired response of blood neutrophils to cell-death stimulus differentiates AQP4-IgG-seropositive NMOSD from MOGAD38
Transcriptomic analysis unveils bona fide molecular signatures of microglia under conditions of homeostasis and viral encephalitis38
Bone marrow–derived emergency monopoiesis drives brain–lung axis injury after traumatic brain injury via IL-138
IL-10 production by granulocytes promotes Staphylococcus aureus craniotomy infection38
Temporal changes in regulatory T cell subsets defined by the transcription factor Helios in stroke and their potential role in stroke-associated infection: a prospective case–control study38
Sublytic pyroptosis blocks Schwann cell remyelination through caspase-1-mediated Tyro3 cleavage38
Soluble CSF1R promotes microglial activation and amyloid clearance in alzheimer’s disease38
Inflammation-induced lysosomal dysfunction in human iPSC-derived microglia is exacerbated by APOE 4/4 genotype37
Type I/type III IFN and related factors regulate JEV infection and BBB endothelial integrity37
Impairment of neuronal tyrosine phosphatase STEP worsens post-ischemic inflammation and brain injury under hypertensive condition37
MAVS signaling shapes microglia responses to neurotropic virus infection37
Effects of diabetes on microglial physiology: a systematic review of in vitro, preclinical and clinical studies37
Glymphatic dysfunction contributes to thalamic iron retention and secondary thalamic injury after stroke: evidence from primates and rodents37
Supraphysiologic doses of 17β-estradiol aggravate depression-like behaviors in ovariectomized mice possibly via regulating microglial responses and brain glycerophospholipid metabolism36
P2X7-CaMKII drives 5-LOX nuclear translocation to impair microglial function after subarachnoid hemorrhage36
Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis36
RiboTag-based RNA profiling uncovers oligodendroglial lineage-specific inflammation in autoimmune encephalomyelitis: implications for pathogenesis36
Temporally resolved single-cell RNA sequencing reveals protective and pathological responses during herpes simplex virus CNS infection36
Intermittent theta-burst stimulation improves motor function by inhibiting neuronal pyroptosis and regulating microglial polarization via TLR4/NFκB/NLRP3 signaling pathway in cerebral ischemic mice36
Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease35
Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease35
AAV-mediated delivery of a proliferation inducing ligand (APRIL) to cortical neurons limits inflammation and demyelination in the corpus callosum of the cuprizone mouse model35
Impact of noradrenergic inhibition on neuroinflammation and pathophysiology in mouse models of Alzheimer’s disease35
Deletion of CD47 from Schwann cells and macrophages hastens myelin disruption/dismantling and scavenging in Schwann cells and augments myelin debris phagocytosis in macrophages35
Immune subversion by Leishmania infantum parasites suppresses NLRP3-driven inflammatory responses in amyloid-β-activated microglia35
CAR T cells as novel therapeutic strategy for multiple sclerosis and other neuroimmune disorders35
Western diet increases brain metabolism and adaptive immune responses in a mouse model of amyloidosis35
Hypothalamic kisspeptin alleviates myasthenia gravis by regulating Th1/Th17/Treg balance through Inhibition of NF-κB signaling pathway35
Fascin-1 limits myosin activity in microglia to control mechanical characterization of the injured spinal cord35
Upregulated astrocytic HDAC7 induces depression-like disorders via deacetylating PINK1 and inhibiting mitophagy35
Microglia and Immune cells interactions in multiple sclerosis cognitive impairment: a postmortem study34
Interleukin-9 protects from microglia- and TNF-mediated synaptotoxicity in experimental multiple sclerosis34
Transcriptional and neuroprotective effects of hexokinase-2 inhibitors administered after stroke34
Models of microglia depletion and replenishment elicit protective effects to alleviate vascular and neuronal damage in the diabetic murine retina34
N-acetylglucosamine inhibits inflammation and neurodegeneration markers in multiple sclerosis: a mechanistic trial34
Role of myeloid cells in ischemic retinopathies: recent advances and unanswered questions34
Sigma-1 receptor regulates HIV-1 and methamphetamine-induced endothelial/pericyte barrier impairment via strain-specific inflammatory responses and mitochondrial dysregulation34
Differential contribution of THIK-1 K+ channels and P2X7 receptors to ATP-mediated neuroinflammation by human microglia34
Neuroimmune proteins can differentiate between tauopathies34
Perivascular macrophages in high-fat diet-induced hypothalamic inflammation34
Microglia sustain anterior cingulate cortex neuronal hyperactivity in nicotine-induced pain34
P2X7 receptor antagonists modulate experimental autoimmune neuritis via regulation of NLRP3 inflammasome activation and Th17 and Th1 cell differentiation33
Moss-derived human complement factor H modulates retinal immune response and attenuates retinal degeneration33
DNA methylation regulation of CYP450-lipid metabolism by high-altitude hypoxia: linking neuroinflammation to cognitive impairment33
Up-regulated succinylation modifications induce a senescence phenotype in microglia by altering mitochondrial energy metabolism33
Ambient RNAs removal of cortex-specific snRNA-seq reveals Apoe+ microglia/macrophage after deeper cerebral hypoperfusion in mice33
Integrated single-cell transcriptomics of cerebrospinal fluid cells in treatment-naïve multiple sclerosis33
Distinct features of B cell receptors in neuromyelitis optica spectrum disorder among CNS inflammatory demyelinating diseases33
Interleukin-6 deficiency reduces neuroinflammation by inhibiting the STAT3-cGAS-STING pathway in Alzheimer’s disease mice33
Repeated LPS induces training and tolerance of microglial responses across brain regions33
Fatty acids role in multiple sclerosis as “metabokines”33
The novel HS-mimetic, Tet-29, regulates immune cell trafficking across barriers of the CNS during inflammation33
Retraction Note: Neuroprotective effects of the Immunomodulatory drug FK506 in a model of HIV1-gp120 neurotoxicity32
Synergistic effects of repeated transcranial magnetic stimulation and mesenchymal stem cells transplantation on alleviating neuroinflammation and PANoptosis in cerebral ischemia32
Using zebrafish to understand reciprocal interactions between the nervous and immune systems and the microbial world32
Japanese encephalitis virus-induced DNA methylation contributes to blood-brain barrier permeability by modulating tight junction protein expression32
Microglial clearance, neuroprotection and cognitive recovery via a novel synthetic sulfolipid in Alzheimer’s disease32
Tumor necrosis factor regulates leukocyte recruitment but not bacterial persistence during Staphylococcus aureus craniotomy infection32
Neuroimmune modulation in liver pathophysiology32
LncBADR promotes T cell-mediated autoimmunity by binding Mccc1 and Pcca to regulate BCAAs degradation32
SPOCK2 modulates neuropathic pain by interacting with MT1-MMP to regulate astrocytic MMP-2 activation in rats with chronic constriction injury32
Hippocampal microRNA-26a-3p deficit contributes to neuroinflammation and behavioral disorders via p38 MAPK signaling pathway in rats32
Astroglial modulation of synaptic function in the non-demyelinated cerebellar cortex is dependent on MyD88 signaling in a model of toxic demyelination31
Growth differentiation factor 15 aggravates sepsis-induced cognitive and memory impairments by promoting microglial inflammatory responses and phagocytosis31
H3K18 lactylation-mediated nucleotide-binding oligomerization domain-2 (NOD2) expression promotes bilirubin-induced pyroptosis of astrocytes31
The interaction of tPA with NMDAR1 drives neuroinflammation and neurodegeneration in α-synuclein-mediated neurotoxicity31
Characterizing CSF inflammatory proteomics in pediatric post-hemorrhagic hydrocephalus and Anti-NMDAR encephalitis31
The protective PLCγ2-P522R variant mitigates Alzheimer’s disease-associated pathologies by enhancing beneficial microglial functions31
The brain washing system in sepsis-associated encephalopathy31
Glyceryl triacetate promotes blood–brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice31
Aberrant copper metabolism and hepatic inflammation cause neurological manifestations in a mouse model of Wilson’s disease31
Single cell RNA sequencing after moderate traumatic brain injury: effects of therapeutic hypothermia31
Mitochondrial protective effects caused by the administration of mefenamic acid in sepsis31
Infiltrating myeloid cell-derived properdin markedly promotes microglia-mediated neuroinflammation after ischemic stroke31
Oxygen therapy attenuates neuroinflammation after spinal cord injury31
The role of CD56bright NK cells in neurodegenerative disorders30
Fucoidan reduces NET accumulation and alleviates chemotherapy-induced peripheral neuropathy via the gut–blood–DRG axis30
Cholesterol in the CNS: functions, recycling and remyelination30
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