FEBS Journal

Article	Citations
Table of Contents	412
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Table of Contents	221
Issue Information	212
Table of Contents	160
Table of Contents	135
Table of Contents	116
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The FEBS Journal in 2025: in all science, error precedes the truth	111
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Site 1 protease aggravates acute kidney injury by promoting tubular epithelial cell ferroptosis through SIRT3‐SOD2‐mtROS signaling	79
Lysine demethylase 4A : from chromatin to centrosomes	68
A novel hexameric NADP+‐reducing [FeFe] hydrogenase from Moorella thermoacetica	68
The calcium‐sensing receptor alleviates endothelial inflammation in atherosclerosis through regulation of integrin β1‐NLRP3 inflammasome	63
The role of the gut microbiome in disorders of gut–brain interaction	61
A genome‐wide CRISPR screen identifies USP1 as a novel regulator of the mammalian circadian clock	61
Exploring the roles of conserved context‐dependent cis‐regulatory elements (cdCREs) in multicellularity, human health and disease	59
Calcium‐induced structural transitions are central to the folding, function, and processing of serratiopeptidase zymogen into mature form	54
MLDSR, the transcriptional regulator of the major lipid droplets protein MLDS, is controlled by long‐chain fatty acids and contributes to the lipid‐accumulating phenotype in olea	54
Pyruvate dehydrogenase phosphatase 1 (PDP1) stimulates HIF activity by supporting histone acetylation under hypoxia	53
On the track of intramembrane clippers: the SPPL2a/b proteases caught in the act in animal models	53
CARPs regulate STUB1 and its pathogenic mutants aggregation kinetics by mono‐ubiquitination	51
Protein succinylome analysis identifies citrate synthase as a central regulator of osteoclast metabolic activity	51
The interaction network of the proteasome assembly chaperone PSMD9 regulates proteostasis	50
Structural and functional characterization of the newly identified Photorhabdus laumondii tumor necrosis factor‐like lectin	50

The importin‐alpha superfamily engages in ethylene signaling by shuttling ETHYLENE INSENSITIVE 2 from the endoplasmic reticulum to the nucleus	49
Tissue integrity at the root of Metazoa – transcriptional landscape of whole‐body regeneration in sponges	48
Impact of N‐linked glycans on the dual short fibulin/ LTBP ‐4 axes regulating elastogenesis	47
Intercellular mitochondrial transfer contributes to microenvironmental redirection of cancer cell fate	44
Identification and functional analysis of a new type of Z,E ‐mixed prenyl reductase from mycobacteria	42
Inhibition of epithelial‐to‐mesenchymal transition augments antitumor efficacy of nanotherapeutics in pancreatic ductal adenocarcinoma	42
Lipofuscin labeling through biorthogonal strain‐promoted azide‐alkyne cycloaddition for the detection of senescent cells	42
Full activation of thermogenesis in brown adipocytes requires Basigin action	41
Regulation of bacterial Type III Secretion System export gate opening by substrates and the FliJ stalk of the flagellar ATPase	41
Succinate receptor 1 signaling mutually depends on subcellular localization and cellular metabolism	39
Nizp1 is a specific NUP98 ‐ NSD1 functional interactor that regulates NUP	39
Regulation of cardiovascular and cardiac functions by caveolins	38
A novel gyrase inhibitor from toxin–antitoxin system expressed by Staphylococcus aureus	38
The biophysical and compositional properties of human basement membranes	38
A novel allosteric site employs a conserved inhibition mechanism in human kidney‐type glutaminase	37
Metabolite‐derived damage‐associated molecular patterns in immunological diseases	35
Deciphering the tight metabolite‐level regulation of glucose‐1‐phosphate adenylyltransferase ( GlgC ) for glycogen synthesis in cyanobacteria	34
Obesity, white adipose tissue and cancer	34
SMAR1 and p53‐regulated lncRNA RP11 ‐ 431M3 .1 enhances	34
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Table of Contents	33
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Take a breath: oxygen sensing of epidermal differentiation	31
Mlg1, a yeast acyltransferase located in ER membranes associated with mitochondria (MAMs), is involved in de novo synthesis and remodelling of phospholipids	31
New links for meprin β within the protease web	31
Table of Contents	31
Table of Contents	31
Glow‐type conversion and characterization of a minimal luciferase via mutational analyses	31
Roles and applications of autophagy in guarding against environmental stress and DNA damage in Saccharomyces cerevisiae	30
Correction to “Structural determinants of cold activity and glucose tolerance of a family 1 glycoside hydrolase (GH1) from Antarctic Marinomonas sp. ef1”	30
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Proteolytic cleavage of the TGFβ co‐receptor CD109 changes its conformation, resulting in protease inhibition via activation of its thiol ester, and dissociation from the cell me	30
Issue Information	30
The role of lysosomal membrane proteins in autophagy and related diseases	29
What's in a name: the multifaceted function of DNA‐ and RNA‐binding proteins in T cell responses	29
Issue Information	29
Biochemical and structural characterization of chlorite dismutase enzyme from Pseudomonas aeruginosa	29
Multifaceted multivalency with a hub protein	29
AXIN2 is a non‐redundant regulator of AXIN1 stability and β‐catenin in colorectal cancer cells	29
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Navigating centriolar satellites: the role of PCM1 in cellular and organismal processes	28
Anchoring of hyaluronan glycocalyx to CD44 reduces sensitivity of HER2‐positive gastric cancer cells to trastuzumab	28
Plasmodium mitochondrial exodeoxyribonucleases, Exo mit1 and Exo mit2 ,	28
Structural features determining the vitamin K epoxide reduction activity in the VKOR family of membrane oxidoreductases	27
A guide to building the matrisome interactome: from computational predictions to experimental validation	27
The mycobacterial guaB1 gene encodes a guanosine 5′‐monophosphate reductase with a cystathionine‐β‐synthase domain	27
Ionizing radiation inhibits zebrafish embryo hatching through induction of tissue inhibitors of metalloproteinases ( TIMP s) expression	26
Synthetic cannabinoid receptor agonists are monoamine oxidase‐A selective inhibitors	26
Characterization of multiple lysophosphatidic acid acyltransferases in the plant pathogen Xanthomonas campestris	26

Proximal deposition of collagen IV by fibroblasts contributes to basement membrane formation by colon epithelial cells in vitr	26
The CGA codon decoding through tRNA Arg	26
Substrate preference, RNA binding and active site versatility of Stenotrophomonas maltophilia nuclease	25
Analysis of mutually exclusive expression in cancer cells identifies a previously unknown intergenic regulatory paradigm	25
A major conformational change of N‐terminal helices of Bacillus thuringiensis Cry1Ab insecticidal protein is necessary for	25
Structural and functional dissection of the WH2 / DAD motif of INF2	25
Multisubstrate‐based system: a kinetic mechanism study of catechol‐ O ‐methyltransferase	24
Modifying inhibitor specificity for homologous enzymes by machine learning	24
Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH si	24
Alternative substrate‐assisted hydrolysis pathways of posttransfer editing by prokaryotic leucyl‐ tRNA synthetase	24
A guide to ferroptosis, the biological rust of cellular membranes	23
Preferential redox regulation of cysteine‐based protein tyrosine phosphatases: structural and biochemical diversity	23
Salmonella ‐driven intestinal edema in mice is characterized by tensed fibronectin fibers	23
Fibrillation of α‐synuclein triggered by bacterial endotoxin and lipid vesicles is modulated by N‐terminal acetylation and familial Parkinson's disease mutations	23
The SARS ‐ CoV ‐2 spike protein interacts with HAX1	23
FAM237A , rather than peptide PEN and proCCK56 ‐63, binds to and ac	23
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RAGE induces physiological activation of NADPH oxidase in neurons and astrocytes and neuroprotection	22
Motif‐driven protein binder design towards transferrin receptor helical domain	22
Table of Contents	22
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Issue Information	20
Issue Information	20
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Defects of the spliceosomal gene SNRPB affect osteo‐ and chondro‐differentiation	20
Further diversity in the origins of fish antifreeze proteins	20
Words of advice: teaching macromolecular crystallography	20
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Structural analysis of the peptidoglycan DL‐endopeptidase CwlO complexed with its inhibitory protein IseA	20
Physical and functional interactions between LDLR family members and CXCR4 in breast cancer	19
Biostimulants in plant brassinosteroid hormone receptor BRI1 activation—a new system to evaluate activation capacity	19
Structure‐based engineering of a short‐chain cis‐prenyltransferase to biosynthesize nonnatural all‐cis‐polyisoprenoids: molecular mechanisms for primer substrate recognition and ultimate	19
Ageing versus developmental silencing: Answers from the epigenome	19
Identification and structural characterization of a novel acetyl xylan esterase from Aspergillus oryzae	19
Less is better: various means to reduce protein load in the endoplasmic reticulum	19
Interactions of the maternal microbiome with diet, stress, and infection influence fetal development	19
Structural and functional insights into the flexible β‐hairpin of glycerol dehydrogenase	19
Biogenesis of fibrils requires C‐mannosylation of PMEL	19
The deubiquitinating enzyme USP 8 promotes tyrosine kinase inhibitors resistance in chronic myeloid leukemia by stabilizing	19
Group A Streptococcus interacts with glycosaminoglycans via M proteins to modulate bacterial adherence in vitro	19
Functional role of lncRNAs in gastrointestinal malignancies: the peculiar case of small nucleolar RNA host gene family	19
Biophysical investigation of the molecular interaction between minichromosome maintenance protein 6 and Bloom syndrome helicase	19
ENKD1 is a centrosomal and ciliary microtubule‐associated protein important for primary cilium content regulation	18
11‐Cl‐BBQ , a select modulator of AhR ‐regulated transcription, suppresses lung cancer cell growth via activation of p	18
Ser38‐His93‐Asn91 triad confers resistance of JFH1 HCV NS5A‐Y93H variant to NS5A inhibitors	18
Proline‐directed yeast and human MAP kinases phosphorylate the Dot1p/ DOT1L histone	18
A novel tdTomato transgenic mouse model to visualize FAP‐positive cancer‐associated fibroblasts	18
Impact of structural dynamics on biological functions of flaviviruses	18
Rafoxanide, a salicylanilide anthelmintic, interacts with human plasma protein transthyretin	18
ZBTB7A regulates primed‐to‐naïve transition of pluripotent stem cells via recognition of the PNT‐associated sequence by zinc fingers 1–2 and recognition of γ‐globin −200 gene element by zinc fingers 1	18
Protein tandem repeats that produce frameshifts can generate new structural states and functions	18
Augmenter of liver regeneration (ALR) can regulate iron homeostasis through the INOS/NO/SLC39A14 pathway to reduce ferroptosis in acute kidney injury	18
Cytoskeletal protein Zyxin in embryonic development: from controlling cell movements and pluripotency to regulating embryonic patterning	17
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Phosphatidic acid induces cytoskeletal rearrangements through the Src‐FAK‐RhoA/ROCK signaling pathway during decidualization	17
PEMT ‐mediated phospholipid imbalance promotes age‐associated metabolic dysfunction‐associated steatotic liver disease progression	17
GDH1 exacerbates renal fibrosis by inhibiting the transcriptional activity of peroxisome proliferator‐activated receptor gamma	17
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Retraction statement: Quercetin induces endoplasmic reticulum stress to enhance cDDP cytotoxicity in ovarian cancer: involvement of STAT3 signaling	17
LRP1 is the cell‐surface endocytosis receptor for vaspin in adipocytes	17
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A comparative study of N‐hydroxylating flavoprotein monooxygenases reveals differences in kinetics and cofactor binding	16
Lysophospholipid acyltransferase‐mediated formation of saturated glycerophospholipids maintained cell membrane integrity for hypoxic adaptation	16
The environmental impact of extracellular matrix preparation	16
A year in the molecular life sciences: 2024 highlights	16
M1‐linked ubiquitination facilitates NF‐κB activation and survival during sterile inflammation	16
Corrigendum to ‘Cryo‐EM structure of MsbA in saposin‐lipid nanoparticles (Salipro) provides insights into nucleotide coordination’	16
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The emerging role of PKM in keratinocyte homeostasis and pathophysiology	16
Comprehensive insulin receptor phosphorylation dynamics profiled by mass spectrometry	16
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Evidence for corrin biosynthesis in the last universal common ancestor	16
Crystal structure and biophysical characterisation of the enterococcal foldase PpiC , a cross‐opsonic antigen against gram‐positive nosocomial pathog	16
High dietary protein and fat contents exacerbate hepatic senescence and SASP in mice	15
Cycloserine enantiomers inhibit PLP‐dependent cysteine desulfurase SufS via distinct mechanisms	15
Derivatives of MOPS : promising scaffolds for SARS coronaviruses Macro domain‐targeted inhibition	15
Structure–activity analysis of imino‐pyrimidinone‐fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors	15
Structural insights into α‐(1→6)‐linkage preference of GH 97 glucodextranase from Flavobacterium johnsoniae	15

Rational engineering of AA5_2 copper radical oxidases to probe the molecular determinants governing their substrate selectivity	15
Structural and interaction analysis of human lipocalin‐type prostaglandin D synthase with the poorly water‐soluble drug NBQX	15
Investigating the molecular mechanisms underlying the anti‐ CRISPR function of AcrIIA13b protein	15
Maize CDKA2 ;1a and CDKB1 ;1 kinases have different requirements for their activation and particip	15
Conditional deletion of the multiple sclerosis susceptibility gene ATXN1 identifies cell‐autonomou	15
Tudor staphylococcal nuclease (Tudor‐ SN ) regulates activation of quiescent hepatic stellate cells	15
Gal‐1 promotes lung cancer cell survival by enhancing PARP1 / H1 .2 interaction to promote	15
Teleost‐specific ictacalcins exhibit similar structural organization, cation‐dependent activation, and transcriptional regulation as human S100 prote	14
Characterisation of an unusual cysteine pair in the Rieske carnitine monooxygenase CntA catalytic site	14
Identification of a novel d‐amino acid aminotransferase involved in d‐glutamate biosynthetic pathways in the hyperthermophile Thermotoga maritima	14
Is it possible to measure good science?	14
Mitochondrial dysfunction and cisplatin sensitivity in gastric cancer: GDF15 as a master player	14
Nemo‐like kinase blocks myeloid differentiation by targeting tumor suppressor C/EBPα in AML	14
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The m6A demethylase FTO promotes C/ EBPβ ‐	14
Atomic solution structure of Mycobacterium abscessusF‐ATP synthase subunit ε and identification of Ep1MabF1 as a targeted inhibitor	14
Interleukin‐1 family cytokines at the crossroads of microbiome regulation in barrier health and disease	14
Neutrophil extracellular traps boost laser‐induced mouse choroidal neovascularization through the activation of the choroidal endothelial cell TLR4/HIF‐1α pathway	14
Understanding the catalytic mechanism of the triazine hydrolase from Arthrobacter aurescens TC1	14
AKT1 mediates multiple phosphorylation events that functionally promote HSF1 activation	14
Pannexin 1 crosstalk with the Hippo pathway in malignant melanoma	13
Cell wall‐resident proteins with internal repeats ( PIR s) show an inverted architecture in Neurospora crassa	13
Rewarding excellence: the 2024 FEBS Journal Richard Perham prize	13
The c‐di‐ AMP ‐binding protein CbpB modulates the level of ppGpp	13
The dual roles of three MMPs and TIMP in innate immunity and metamorphosis in the silkworm, Bombyx mori	13
Mitochondrial dysfunction decreases cisplatin sensitivity in gastric cancer cells through upregulation of integrated stress response and mitokine GDF15	13
The small molecule ZPD ‐2 inhibits the aggregation and seeded polymerisation of C‐terminally truncated α‐Synuclein	13
Issue Information	13
Issue Information	13
Dual‐Cys bacteriophytochromes: intermediates in cyanobacterial phytochrome evolution?	13
Direct capture, inhibition and crystal structure of HsaD (Rv3569c) from M. tuberculosis	13
Molecular basis of domain‐specific angiotensin I‐converting enzyme inhibition by the antihypertensive drugs enalaprilat, ramiprilat, trandolaprilat, quinaprilat and perindoprilat	13
Dietary restriction and lifespan: adaptive reallocation or somatic sacrifice?	13
Understanding HAIs: Ally proteins in the fight against cancer	13
PU .1 and TGF ‐β signaling activate the cell‐surface expression of CD103	13
Electrostatic potential as a reactivity scoring function in computer‐assisted enzyme engineering	13
Metal ion activation and DNA recognition by the Deinococcus radiodurans manganese sensor	12
A comprehensive overview of yeast libraries and their role in advancing cell biology	12
PGE2 pathway mediates oxidative stress‐induced ferroptosis in renal tubular epithelial cells	12
Mutant p53 affects the mitochondrial proteome, promoting mitochondrial fragmentation and OXPHOS in pancreatic ductal adenocarcinoma cells	12
Gut microbiota in multiple sclerosis and animal models	12
Table of Contents	12
Role of the polycystic kidney disease domain in matriptase chaperone activity and localization of hepatocyte growth factor activator inhibitor‐1	12
Context‐dependent roles of cellular senescence in normal, aged, and disease states	12
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The antihypertensive agent ACT ‐132577 alleviates cuproptosis and pressure‐overload‐induced vascular remodelling by modulation of the NEDD4‐LCTR1‐cop	12
GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators	12
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Metalloprotease‐mediated cleavage of CD95 ligand	12
Biogenesis of hepatitis B virus e antigen is driven by translocon‐associated protein complex and regulated by conserved cysteine residues within its signal peptide sequence	12
Sox9/CXCL5 axis facilitates tumour cell growth and invasion in hepatocellular carcinoma	12
Mechanism of cyanobacterial ferredoxin‐dependent flavin thioredoxin reductase reveals thiolate‐FAD charge transfer and catalytic asymmetry in a homodimer	12
Issue Information	12
Effects of senescence on the tumour microenvironment and response to therapy	12
Lung organoids as a human system for Mycobacteria infection modeling and drug testing	11
Raft platforms highly enriched in cholesterol: major scaffolds for IL‐6 signalling assembly with implications in inflammation and cancer	11
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Multi‐omics characterization of synthetic lethality‐related molecular features: implications for SL‐based therapeutic target screening	11
TBK1 is involved in M‐CSF‐induced macrophage polarization through mediating the IRF5/IRF4 axis	11
Therapeutic opportunities for senolysis in cardiovascular disease	11
Membrane anchoring of New Delhi metallo‐β‐lactamase‐1 alters the fitness of Escherichia coli and increases its susceptibility to colistin by inducing out	11
GR‐KLF15 pathway controls hepatic lipogenesis during fasting	11
Chromatin folding by the Polycomb group proteins and its elusive role in epigenetic repression	11
Issue Information	11
Table of Contents	11
Regulation of intrinsic and extrinsic metabolic pathways in tumour‐associated macrophages	11
TDP‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models	11
Mitochondrial derived vesicles‐ Quo Vadis?	11
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Pinocembrin alleviates renal ischemia–reperfusion injury/unilateral ureteral obstruction (UUO)‐generated renal fibrosis by targeting the CYP1B1/ROS/MAPK axi	11
The chemoreceptor controlling the Wsp‐like transduction pathway in Halomonas titanicaeKHS3 binds and responds to purine derivatives	11
Issue Information	11
Editor Profile: Daniel Longley	11
Insights into the mechanisms of neuron generation and specification in the zebrafish ventral spinal cord	11
Responses of animals and plants to physiological doses of ethanol: a molecular messenger of hypoxia?	11
Tracing the evolutionary pathway: on the origin of mitochondria and eukaryogenesis	11
In conversation with Małgorzata Kosla	11
Correction to “Bimodal substrate binding in the active site of the glycosidase BcX”	10
Viscosity regulates cell spreading and cell‐extracellular matrix interactions	10
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The structural, functional, and diagnostic significance of NINJ1 in ferroptosis‐related diseases	10
Extracellular vesicles promote autophagy in human microglia through lipid raft‐dependent mechanisms	10
Therapeutic outlooks for Gal‐1 and genotoxic agents	10
When the host senses the microbiota's metabolism – the interplay between food and microbiota in C. elegans	10
Issue Information	10
Autophagy of the ER: the secretome finds the lysosome	10
In conversation with Lori Passmore	10
In conversation with Carol Robinson	10
Distribution and activity of nitrate and nitrite reductases in the microbiota of the human intestinal tract	10
Tumor immune evasion: insights from CRISPR screens and future directions	10
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Protein biochemistry and engineering drive the development of a carbonic anhydrase‐based carbon dioxide sequestration strategy	10
Sorting nexins: role in the regulation of blood pressure	10
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Issue Information	10