FEBS Journal

Article	Citations
Table of Contents	431
	285
Table of Contents	235
Issue Information	143
Table of Contents	120
Table of Contents	120
Table of Contents	114
	109
The FEBS Journal in 2025: in all science, error precedes the truth	69
Regulation of cardiovascular and cardiac functions by caveolins	68
The biophysical and compositional properties of human basement membranes	68
	64
A novel hexameric NADP+‐reducing [FeFe] hydrogenase from Moorella thermoacetica	61
Lysine demethylase 4A : from chromatin to centrosomes	61
The role of the gut microbiome in disorders of gut–brain interaction	58
MLDSR, the transcriptional regulator of the major lipid droplets protein MLDS, is controlled by long‐chain fatty acids and contributes to the lipid‐accumulating phenotype in olea	55
Calcium‐induced structural transitions are central to the folding, function, and processing of serratiopeptidase zymogen into mature form	55
A genome‐wide CRISPR screen identifies USP1 as a novel regulator of the mammalian circadian clock	55
On the track of intramembrane clippers: the SPPL2a/b proteases caught in the act in animal models	54
A novel allosteric site employs a conserved inhibition mechanism in human kidney‐type glutaminase	53
Pyruvate dehydrogenase phosphatase 1 (PDP1) stimulates HIF activity by supporting histone acetylation under hypoxia	53
The calcium‐sensing receptor alleviates endothelial inflammation in atherosclerosis through regulation of integrin β1‐NLRP3 inflammasome	52
Tissue integrity at the root of Metazoa – transcriptional landscape of whole‐body regeneration in sponges	50
Impact of N‐linked glycans on the dual short fibulin/ LTBP ‐4 axes regulating elastogenesis	49
Intercellular mitochondrial transfer contributes to microenvironmental redirection of cancer cell fate	44

Lipofuscin labeling through biorthogonal strain‐promoted azide‐alkyne cycloaddition for the detection of senescent cells	43
Identification and functional analysis of a new type of Z,E ‐mixed prenyl reductase from mycobacteria	43
CARPs regulate STUB1 and its pathogenic mutants aggregation kinetics by mono‐ubiquitination	42
The interaction network of the proteasome assembly chaperone PSMD9 regulates proteostasis	41
Structural and functional characterization of the newly identified Photorhabdus laumondii tumor necrosis factor‐like lectin	40
The importin‐alpha superfamily engages in ethylene signaling by shuttling ETHYLENE INSENSITIVE 2 from the endoplasmic reticulum to the nucleus	40
Succinate receptor 1 signaling mutually depends on subcellular localization and cellular metabolism	39
Nizp1 is a specific NUP98 ‐ NSD1 functional interactor that regulates NUP	39
Inhibition of epithelial‐to‐mesenchymal transition augments antitumor efficacy of nanotherapeutics in pancreatic ductal adenocarcinoma	39
Protein succinylome analysis identifies citrate synthase as a central regulator of osteoclast metabolic activity	36
Full activation of thermogenesis in brown adipocytes requires Basigin action	36
Metabolite‐derived damage‐associated molecular patterns in immunological diseases	36
A novel gyrase inhibitor from toxin–antitoxin system expressed by Staphylococcus aureus	35
Exploring the roles of conserved context‐dependent cis‐regulatory elements ( cdCREs ) in multicellularity, human health and disease	35
Mechanism for synthesis of isomaltooligosaccharides from maltooligosaccharides by GH 15 α‐glucan 4(6)‐α‐glucosyltransferase	34
SMAR1 and p53‐regulated lncRNA RP11 ‐ 431M3 .1 enhances	34
Site 1 protease aggravates acute kidney injury by promoting tubular epithelial cell ferroptosis through SIRT3‐SOD2‐mtROS signaling	34
Obesity, white adipose tissue and cancer	33
Deciphering the tight metabolite‐level regulation of glucose‐1‐phosphate adenylyltransferase ( GlgC ) for glycogen synthesis in cyanobacteria	33
Detection of endogenous LINE ‐1 ORF2p and its potent reverse transcriptase activity in the	32
Table of Contents	32
Table of Contents	31
	31
Table of Contents	31
	31
Mlg1, a yeast acyltransferase located in ER membranes associated with mitochondria (MAMs), is involved in de novo synthesis and remodelling of phospholipids	30
Table of Contents	30
Take a breath: oxygen sensing of epidermal differentiation	29
Roles and applications of autophagy in guarding against environmental stress and DNA damage in Saccharomyces cerevisiae	29
Glow‐type conversion and characterization of a minimal luciferase via mutational analyses	29
	29
New links for meprin β within the protease web	29
Issue Information	29
Plasmodium mitochondrial exodeoxyribonucleases, Exo mit1 and Exo mit2 ,	28
Proteolytic cleavage of the TGFβ co‐receptor CD109 changes its conformation, resulting in protease inhibition via activation of its thiol ester, and dissociation from the cell me	28
Biochemical and structural characterization of chlorite dismutase enzyme from Pseudomonas aeruginosa	28
	28
AXIN2 is a non‐redundant regulator of AXIN1 stability and β‐catenin in colorectal cancer cells	28
Correction to “Structural determinants of cold activity and glucose tolerance of a family 1 glycoside hydrolase (GH1) from Antarctic Marinomonas sp. ef1”	28
Multifaceted multivalency with a hub protein	27
A guide to building the matrisome interactome: from computational predictions to experimental validation	27
Issue Information	27
Characterization of multiple lysophosphatidic acid acyltransferases in the plant pathogen Xanthomonas campestris	26
Proximal deposition of collagen IV by fibroblasts contributes to basement membrane formation by colon epithelial cells in vitr	26
Structural features determining the vitamin K epoxide reduction activity in the VKOR family of membrane oxidoreductases	26
The CGA codon decoding through tRNA Arg	26
Synthetic cannabinoid receptor agonists are monoamine oxidase‐A selective inhibitors	26
Structural and functional dissection of the WH2 / DAD motif of INF2	26
The SARS ‐ CoV ‐2 spike protein interacts with HAX1	25
Alternative substrate‐assisted hydrolysis pathways of posttransfer editing by prokaryotic leucyl‐ tRNA synthetase	25

Salmonella ‐driven intestinal edema in mice is characterized by tensed fibronectin fibers	25
Modifying inhibitor specificity for homologous enzymes by machine learning	25
Fibrillation of α‐synuclein triggered by bacterial endotoxin and lipid vesicles is modulated by N‐terminal acetylation and familial Parkinson's disease mutations	25
Dimerization‐dependent NOTCH receptor transactivation unveils a class of highly selective NOTCH si	25
Preferential redox regulation of cysteine‐based protein tyrosine phosphatases: structural and biochemical diversity	24
A major conformational change of N‐terminal helices of Bacillus thuringiensis Cry1Ab insecticidal protein is necessary for	24
What's in a name: the multifaceted function of DNA‐ and RNA‐binding proteins in T cell responses	23
Multisubstrate‐based system: a kinetic mechanism study of catechol‐ O ‐methyltransferase	22
New insights into macrophage heterogeneity in renal injury and repair	22
FAM237A , rather than peptide PEN and proCCK56 ‐63, binds to and ac	22
RAGE induces physiological activation of NADPH oxidase in neurons and astrocytes and neuroprotection	22
Analysis of mutually exclusive expression in cancer cells identifies a previously unknown intergenic regulatory paradigm	22
Substrate preference, RNA binding and active site versatility of Stenotrophomonas maltophilia nuclease	21
The mycobacterial guaB1 gene encodes a guanosine 5′‐monophosphate reductase with a cystathionine‐β‐synthase domain	21
Anchoring of hyaluronan glycocalyx to CD44 reduces sensitivity of HER2‐positive gastric cancer cells to trastuzumab	21
Navigating centriolar satellites: the role of PCM1 in cellular and organismal processes	21
A guide to ferroptosis, the biological rust of cellular membranes	21
The role of lysosomal membrane proteins in autophagy and related diseases	21
Ionizing radiation inhibits zebrafish embryo hatching through induction of tissue inhibitors of metalloproteinases ( TIMP s) expression	20
Table of Contents	20
A novel tdTomato transgenic mouse model to visualize FAP‐positive cancer‐associated fibroblasts	20
Issue Information	20
Table of Contents	20
	20
Augmenter of liver regeneration (ALR) can regulate iron homeostasis through the INOS/NO/SLC39A14 pathway to reduce ferroptosis in acute kidney injury	20
	20
Words of advice: teaching macromolecular crystallography	20
	20
Group A Streptococcus interacts with glycosaminoglycans via M proteins to modulate bacterial adherence in vitro	19
Issue Information	19
Biostimulants in plant brassinosteroid hormone receptor BRI1 activation—a new system to evaluate activation capacity	19
	19
Further diversity in the origins of fish antifreeze proteins	19
Structural and functional insights into the flexible β‐hairpin of glycerol dehydrogenase	18
Structure‐based engineering of a short‐chain cis‐prenyltransferase to biosynthesize nonnatural all‐cis‐polyisoprenoids: molecular mechanisms for primer substrate recognition and ultimate	18
A new metabolic path in type 3 rickets	18
PEMT ‐mediated phospholipid imbalance promotes age‐associated metabolic dysfunction‐associated steatotic liver disease progression	18
LRP1 is the cell‐surface endocytosis receptor for vaspin in adipocytes	18
Physical and functional interactions between LDLR family members and CXCR4 in breast cancer	18
Functional role of lncRNAs in gastrointestinal malignancies: the peculiar case of small nucleolar RNA host gene family	18
Ageing versus developmental silencing: Answers from the epigenome	18
Interactions of the maternal microbiome with diet, stress, and infection influence fetal development	18
The deubiquitinating enzyme USP 8 promotes tyrosine kinase inhibitors resistance in chronic myeloid leukemia by stabilizing	18
Rafoxanide, a salicylanilide anthelmintic, interacts with human plasma protein transthyretin	17
Ser38‐His93‐Asn91 triad confers resistance of JFH1 HCV NS5A‐Y93H variant to NS5A inhibitors	17
ZBTB7A regulates primed‐to‐naïve transition of pluripotent stem cells via recognition of the PNT‐associated sequence by zinc fingers 1–2 and recognition of γ‐globin −200 gene element by zinc fingers 1	17
Less is better: various means to reduce protein load in the endoplasmic reticulum	17
	17
Identification and structural characterization of a novel acetyl xylan esterase from Aspergillus oryzae	17
Biophysical investigation of the molecular interaction between minichromosome maintenance protein 6 and Bloom syndrome helicase	17
ENKD1 is a centrosomal and ciliary microtubule‐associated protein important for primary cilium content regulation	17
Biogenesis of fibrils requires C‐mannosylation of PMEL	17
GDH1 exacerbates renal fibrosis by inhibiting the transcriptional activity of peroxisome proliferator‐activated receptor gamma	17
11‐Cl‐BBQ , a select modulator of AhR ‐regulated transcription, suppresses lung cancer cell growth via activation of p	17
Impact of structural dynamics on biological functions of flaviviruses	17
Protein tandem repeats that produce frameshifts can generate new structural states and functions	17
Proline‐directed yeast and human MAP kinases phosphorylate the Dot1p/ DOT1L histone	17
Defects of the spliceosomal gene SNRPB affect osteo‐ and chondro‐differentiation	17
Structural analysis of the peptidoglycan DL‐endopeptidase CwlO complexed with its inhibitory protein IseA	17
	16
	16
	16
Is it possible to measure good science?	16
Characterisation of an unusual cysteine pair in the Rieske carnitine monooxygenase CntA catalytic site	16
	16
The environmental impact of extracellular matrix preparation	16
Understanding the catalytic mechanism of the triazine hydrolase from Arthrobacter aurescens TC1	16
Teleost‐specific ictacalcins exhibit similar structural organization, cation‐dependent activation, and transcriptional regulation as human S100 prote	16
	16
Corrigendum to ‘Cryo‐EM structure of MsbA in saposin‐lipid nanoparticles (Salipro) provides insights into nucleotide coordination’	16
Retraction statement: Quercetin induces endoplasmic reticulum stress to enhance cDDP cytotoxicity in ovarian cancer: involvement of STAT3 signaling	16
Nemo‐like kinase blocks myeloid differentiation by targeting tumor suppressor C/EBPα in AML	16
Structural insights into α‐(1→6)‐linkage preference of GH 97 glucodextranase from Flavobacterium johnsoniae	15
Derivatives of MOPS : promising scaffolds for SARS coronaviruses Macro domain‐targeted inhibition	15
Rational engineering of AA5_2 copper radical oxidases to probe the molecular determinants governing their substrate selectivity	15
Tudor staphylococcal nuclease (Tudor‐ SN ) regulates activation of quiescent hepatic stellate cells	15
Maize CDKA2 ;1a and CDKB1 ;1 kinases have different requirements for their activation and particip	15
Conditional deletion of the multiple sclerosis susceptibility gene ATXN1 identifies cell‐autonomou	15
The emerging role of PKM in keratinocyte homeostasis and pathophysiology	15
The m6A demethylase FTO promotes C/ EBPβ ‐	15

Cycloserine enantiomers inhibit PLP‐dependent cysteine desulfurase SufS via distinct mechanisms	15
Crystal structure and biophysical characterisation of the enterococcal foldase PpiC , a cross‐opsonic antigen against gram‐positive nosocomial pathog	14
Structure–activity analysis of imino‐pyrimidinone‐fused pyrrolidines aids the development of dual plasmepsin V and plasmepsin X inhibitors	14
EHD4 and ASAP2 are critical negative regulators of the claudin‐5‐based endothelial barrier	14
Neutrophil extracellular traps boost laser‐induced mouse choroidal neovascularization through the activation of the choroidal endothelial cell TLR4/HIF‐1α pathway	14
Evidence for corrin biosynthesis in the last universal common ancestor	14
Lysophospholipid acyltransferase‐mediated formation of saturated glycerophospholipids maintained cell membrane integrity for hypoxic adaptation	14
Investigating the molecular mechanisms underlying the anti‐ CRISPR function of AcrIIA13b protein	14
A comparative study of N‐hydroxylating flavoprotein monooxygenases reveals differences in kinetics and cofactor binding	14
Gal‐1 promotes lung cancer cell survival by enhancing PARP1 / H1 .2 interaction to promote	14
A year in the molecular life sciences: 2024 highlights	14
Identification of a novel d‐amino acid aminotransferase involved in d‐glutamate biosynthetic pathways in the hyperthermophile Thermotoga maritima	14
M1‐linked ubiquitination facilitates NF‐κB activation and survival during sterile inflammation	14
Phosphatidic acid induces cytoskeletal rearrangements through the Src‐ FAK ‐ R ho	13
Rewarding excellence: the 2024 FEBS Journal Richard Perham prize	13
Dual‐Cys bacteriophytochromes: intermediates in cyanobacterial phytochrome evolution?	13
Dietary restriction and lifespan: adaptive reallocation or somatic sacrifice?	13
Electrostatic potential as a reactivity scoring function in computer‐assisted enzyme engineering	13
Issue Information	13
Molecular basis of domain‐specific angiotensin I‐converting enzyme inhibition by the antihypertensive drugs enalaprilat, ramiprilat, trandolaprilat, quinaprilat and perindoprilat	13
AKT1 mediates multiple phosphorylation events that functionally promote HSF1 activation	13
The c‐di‐ AMP ‐binding protein CbpB modulates the level of ppGpp	13
Mitochondrial dysfunction and cisplatin sensitivity in gastric cancer: GDF15 as a master player	13
Understanding HAIs: Ally proteins in the fight against cancer	13
	13
PU .1 and TGF ‐β signaling activate the cell‐surface expression of CD103	13
	13
Metal ion activation and DNA recognition by the Deinococcus radiodurans manganese sensor	13
Interleukin‐1 family cytokines at the crossroads of microbiome regulation in barrier health and disease	13
Structural and interaction analysis of human lipocalin‐type prostaglandin D synthase with the poorly water‐soluble drug NBQX	13
Cell wall‐resident proteins with internal repeats ( PIR s) show an inverted architecture in Neurospora crassa	13
Direct capture, inhibition and crystal structure of HsaD (Rv3569c) from M. tuberculosis	13
Issue Information	13
The small molecule ZPD ‐2 inhibits the aggregation and seeded polymerisation of C‐terminally truncated α‐Synuclein	13
Atomic solution structure of Mycobacterium abscessusF‐ATP synthase subunit ε and identification of Ep1MabF1 as a targeted inhibitor	13
Role of the polycystic kidney disease domain in matriptase chaperone activity and localization of hepatocyte growth factor activator inhibitor‐1	13
A comprehensive overview of yeast libraries and their role in advancing cell biology	12
Context‐dependent roles of cellular senescence in normal, aged, and disease states	12
Pannexin 1 crosstalk with the Hippo pathway in malignant melanoma	12
Effects of senescence on the tumour microenvironment and response to therapy	12
Table of Contents	12
Mechanism of cyanobacterial ferredoxin‐dependent flavin thioredoxin reductase reveals thiolate‐FAD charge transfer and catalytic asymmetry in a homodimer	12
The antihypertensive agent ACT ‐132577 alleviates cuproptosis and pressure‐overload‐induced vascular remodelling by modulation of the NEDD4‐LCTR1‐cop	12
PGE2 pathway mediates oxidative stress‐induced ferroptosis in renal tubular epithelial cells	12
Mitochondrial dysfunction decreases cisplatin sensitivity in gastric cancer cells through upregulation of integrated stress response and mitokine GDF15	12
Gut microbiota in multiple sclerosis and animal models	12
Table of Contents	12
Metalloprotease‐mediated cleavage of CD95 ligand	12
A DNA mimic jams the Cas9 scissors	12
Sox9/CXCL5 axis facilitates tumour cell growth and invasion in hepatocellular carcinoma	12
GSH facilitates the binding and inhibitory activity of novel multidrug resistance protein 1 (MRP1) modulators	12
Issue Information	12
Mutant p53 affects the mitochondrial proteome, promoting mitochondrial fragmentation and OXPHOS in pancreatic ductal adenocarcinoma cells	12
Neurokinin‐1 receptor antagonist rolapitant suppresses anxiety and alcohol intake produced by repeated withdrawal episodes	11
Tracing the evolutionary pathway: on the origin of mitochondria and eukaryogenesis	11
Pinocembrin alleviates renal ischemia–reperfusion injury/unilateral ureteral obstruction (UUO)‐generated renal fibrosis by targeting the CYP1B1/ROS/MAPK axi	11
Deciphering the structure and mechanism of action of computer‐designed mastoparan peptides	11
Chromatin folding by the Polycomb group proteins and its elusive role in epigenetic repression	11
Multi‐omics characterization of synthetic lethality‐related molecular features: implications for SL‐based therapeutic target screening	11
Table of Contents	11
Issue Information	11
KIAA0317 regulates SOCS1 stability to ameliorate colonic inflammation	11
DCBLD2 deletion increases hyperglycemia and induces vascular remodeling by inhibiting insulin receptor recycling in endothelial cells	11
Viscosity regulates cell spreading and cell‐extracellular matrix interactions	11
	11
Lung organoids as a human system for Mycobacteria infection modeling and drug testing	11
Research highlights: Hidden gems	11
Insights into the mechanisms of neuron generation and specification in the zebrafish ventral spinal cord	11
Issue Information	11
The chemoreceptor controlling the Wsp‐like transduction pathway in Halomonas titanicaeKHS3 binds and responds to purine derivatives	11
TDP‐43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models	11
Identification of an exosite at the neutrophil elastase/alpha‐1‐antitrypsin interface	11
Membrane anchoring of New Delhi metallo‐β‐lactamase‐1 alters the fitness of Escherichia coli and increases its susceptibility to colistin by inducing out	11
Therapeutic opportunities for senolysis in cardiovascular disease	11
In conversation with Małgorzata Kosla	11
TBK1 is involved in M‐CSF‐induced macrophage polarization through mediating the IRF5/IRF4 axis	11
Comparative analysis of metabolic and functional cardiac alterations in diet‐ and genetically induced mouse models of cardiac dysfunction	11
Raft platforms highly enriched in cholesterol: major scaffolds for IL‐6 signalling assembly with implications in inflammation and cancer	11
	11
Editor Profile: Daniel Longley	11
Regulation of intrinsic and extrinsic metabolic pathways in tumour‐associated macrophages	11
Inhibition of intracellular versus extracellular cathepsin D differentially alters the liver lipidome of mice with metabolic dysfunction‐associated steatohepatitis	11
Issue Information	10
Correction to “Bimodal substrate binding in the active site of the glycosidase BcX”	10
The role of compartmentalized β‐AR/cAMP signaling in the regulation of lipolysis in white and brown adipocytes	10
	10
Extracellular vesicles promote autophagy in human microglia through lipid raft‐dependent mechanisms	10
When the host senses the microbiota's metabolism – the interplay between food and microbiota in C. elegans	10
	10
TSC22D1 is a newly identified inhibitor of insulin secretion in pancreatic beta cells	10
In conversation with Carol Robinson	10
Issue Information	10
Mitochondrial derived vesicles‐ Quo Vadis?	10
GR‐KLF15 pathway controls hepatic lipogenesis during fasting	10
The regulation of liquid‐liquid phase separated condensates containing nucleic acids	10