OOIR: Observatory of International Research

Papers

(The H4-Index of Immunity & Ageing is 24. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Review of evidence linking exposure to environmental stressors and associated alterations in the dynamics of immunosenescence (ISC) with the global increase in multiple sclerosis (MS)	175
Influenza virus infection exacerbates gene expression related to neurocognitive dysfunction in brains of old mice	85
The effects of high plasma levels of Aβ1-42 on mononuclear macrophage in mouse models of Alzheimer’s disease	67
Cumulative physiological stress is associated with age-related changes to peripheral T lymphocyte subsets in healthy humans	56
Natural IgG antibodies to β amyloid are decreased in patients with Parkinson’s disease	51
Pentraxin-3 and C-reactive protein plasma levels predict survival in older adults with or without metabolic syndrome – results of the PolSenior2 substudy	51
Differential associations of anti-cytomegalovirus antibodies and soluble CD14 levels with immunosenescence in people living with HIV on long term antiretroviral therapy	47
Fundamental and frontier research of immune responses to influenza vaccines in human aging: from cross-sectional and longitudinal studies to clinical trials and the geroscience perspective	47
Exploring the link between fat-soluble vitamins and aging-associated immune system status: a literature review	47
Correction to: A novel murine model of multi-day moderate ethanol exposure reveals increased intestinal dysfunction and liver inflammation with age	42
Compositional analysis of lymphocytes and their relationship with health outcomes: findings from the health and retirement study	34
Different peripheral expression patterns of the nicotinic acetylcholine receptor in dementia with Lewy bodies and Alzheimer’s disease	33
Old hematopoietic stem cells retain competence to reconstitute a youthful B cell system that is highly responsive to protein-based vaccination	32
Aging, inflammaging and immunosenescence as risk factors of severe COVID-19	32
Vascular Cell Adhesion Molecule-1 (VCAM-1) contributes to macular fibrosis in neovascular age-related macular degeneration through modulating macrophage functions	32
TAOK3 limits age-associated inflammation by negatively modulating macrophage differentiation and their production of TNFα	30
Immune cell phenotypes and mortality in the Framingham Heart Study	29
Deciphering the impact of aging on splenic endothelial cell heterogeneity and immunosenescence through single-cell RNA sequencing analysis	27
Aging and the impact of global DNA methylation, telomere shortening, and total oxidative status on sarcopenia and frailty syndrome	27
Targeting aging pathways with natural compounds: a review of curcumin, epigallocatechin gallate, thymoquinone, and resveratrol	26
MicroRNA-425-5p modulates osteoporosis by targeting annexin A2	26
The immunosenescence-related factor DOCK11 is involved in secondary immune responses of B cells	26
Correction to: Classical and lectin complement pathways and markers of inflammation for investigation of susceptibility to infections among healthy older adults	25
Systemic immune response in young and elderly patients after traumatic brain injury	24
The aging immune system and all-cause mortality in older americans: differences across sex and race/ethnicity	24

Chitosan alleviates ovarian aging by enhancing macrophage phagocyte-mediated tissue homeostasis