Immunity & Ageing

Papers
(The TQCC of Immunity & Ageing is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)
ArticleCitations
Role of immune cells in the removal of deleterious senescent cells188
Gut microbiota as the key controllers of “healthy” aging of elderly people167
Obesity and COVID-19: what makes obese host so vulnerable?122
The immune response to influenza in older humans: beyond immune senescence98
Aging induces B cell defects and decreased antibody responses to influenza infection and vaccination63
Differential immunogenicity of BNT162b2 or ChAdOx1 vaccines after extended-interval homologous dual vaccination in older people63
The correlation between the Th17/Treg cell balance and bone health63
The lethal sex gap: COVID-1961
A public health perspective of aging: do hyper-inflammatory syndromes such as COVID-19, SARS, ARDS, cytokine storm syndrome, and post-ICU syndrome accelerate short- and long-term inflammaging?59
“The ancient and the new”: is there an interaction between cytomegalovirus and SARS-CoV-2 infection?50
SARS-CoV-2 disease severity and diabetes: why the connection and what is to be done?49
Functional conservation in genes and pathways linking ageing and immunity44
SARS-CoV-2 and mitochondrial health: implications of lifestyle and ageing43
Genetic and environmental determinants of human TCR repertoire diversity42
Macrophage function in the elderly and impact on injury repair and cancer41
Autoimmune hemolytic anemia: current knowledge and perspectives39
Does reactivation of cytomegalovirus contribute to severe COVID-19 disease?38
Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease38
Sex- and age‐dependent alterations of splenic immune cell profile and NK cell phenotypes and function in C57BL/6J mice37
COVID-19: age, Interleukin-6, C-reactive protein, and lymphocytes as key clues from a multicentre retrospective study33
Aging, inflammaging and immunosenescence as risk factors of severe COVID-1930
miR-181a-regulated pathways in T-cell differentiation and aging26
Association between inflammatory cytokines and anti-SARS-CoV-2 antibodies in hospitalized patients with COVID-1925
Aged microglia promote peripheral T cell infiltration by reprogramming the microenvironment of neurogenic niches23
NF-κB, a culprit of both inflamm-ageing and declining immunity?22
Longitudinal profiling of clonal hematopoiesis provides insight into clonal dynamics22
Aging and CMV discordance are associated with increased immune diversity between monozygotic twins21
Vaccination of older adults: Influenza, pneumococcal disease, herpes zoster, COVID-19 and beyond19
Unanticipated efficacy of SARS-CoV-2 vaccination in older adults19
Evaluation of T-cell aging-related immune phenotypes in the context of biological aging and multimorbidity in the Health and Retirement Study18
In-depth immune cellular profiling reveals sex-specific associations with frailty18
Aging and chronic inflammation: highlights from a multidisciplinary workshop18
Obesity-induced neuroinflammation and cognitive impairment in young adult versus middle-aged mice17
Hyper‐metabolic B cells in the spleens of old mice make antibodies with autoimmune specificities16
SARS-CoV-2 and EBV; the cost of a second mitochondrial “whammy”?16
Moderate- to high intensity aerobic and resistance exercise reduces peripheral blood regulatory cell populations in older adults with rheumatoid arthritis15
Emergence of T cell immunosenescence in diabetic chronic kidney disease15
Age-associated changes in the circulating human antibody repertoire are upregulated in autoimmunity15
Phenotypic and functional alterations of monocyte subsets with aging15
Alterations of monocyte NF-κB p65/RelA signaling in a cohort of older medical patients, age-matched controls, and healthy young adults15
Pathogen burden and leukocyte telomere length in the United States14
Inflammation and cell-to-cell communication, two related aspects in frailty14
Association of immunity markers with the risk of incident frailty: the Rugao longitudinal aging study13
Rapamycin, Acarbose and 17α-estradiol share common mechanisms regulating the MAPK pathways involved in intracellular signaling and inflammation13
Neurohormetic phytochemicals in the pathogenesis of neurodegenerative diseases13
An anti-CD6 monoclonal antibody (itolizumab) reduces circulating IL-6 in severe COVID-19 elderly patients13
Telomerase deficiency reflects age-associated changes in CD4+ T cells12
IL-15 deficiency alleviates steroid-induced osteonecrosis of the femoral head by impact osteoclasts via RANKL-RANK-OPG system12
Effect of aging on the transcriptomic changes associated with the expression of the HERV-K (HML-2) provirus at 1q2212
Different phenotypes of microglia in animal models of Alzheimer disease12
A potential association between immunosenescence and high COVID-19 related mortality among elderly patients with cardiovascular diseases12
Frailty impacts immune responses to Moderna COVID-19 mRNA vaccine in older adults11
Toll-like receptor 4 (TLR4): new insight immune and aging11
T cells accumulate in non-diabetic islets during ageing10
Adiponectin deficiency accelerates brain aging via mitochondria-associated neuroinflammation10
C-reactive protein and white blood cell are associated with frailty progression: a longitudinal study10
Metabolic phenotype of B cells from young and elderly HIV individuals10
The impact of circadian rhythms on the immune response to influenza vaccination in middle-aged and older adults (IMPROVE): a randomised controlled trial10
The impact of body mass index on adaptive immune cells in the human bone marrow10
T cell phenotypes associated with insulin resistance: results from the Berlin Aging Study II10
The effect of age on CD4+ T-cell recovery in HIV-suppressed adult participants: a sub-study from AIDS Clinical Trial Group (ACTG) A5321 and the Bone Loss and Immune Reconstitution (BLIR) study9
MicroRNAs: a crossroad that connects obesity to immunity and aging9
Age-associated phenotypic imbalance in TCD4 and TCD8 cell subsets: comparison between healthy aged, smokers, COPD patients and young adults9
Loss of toll-like receptor 4 ameliorates cardiovascular dysfunction in aged mice9
Salutary effects of moderate but not high intensity aerobic exercise training on the frequency of peripheral T-cells associated with immunosenescence in older women at high risk of breast cancer: a ra9
Plasma level of lipocalin 2 is increased in neovascular age-related macular degeneration patients, particularly those with macular fibrosis9
Neutralizing antibody and T cell responses against SARS-CoV-2 variants of concern following ChAdOx-1 or BNT162b2 boosting in the elderly previously immunized with CoronaVac vaccine9
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