Basic & Clinical Pharmacology & Toxicology

Article	Citations
Issue Information	196
Artesunate alleviates intracerebral haemorrhage secondary injury by inducing ferroptosis in M1‐polarized microglia and suppressing inflammation through AMPK/mTORC1/GPX4 pathway	183
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Lithium and the risk of chronic kidney disease: A population‐based case–control study	64
Antioxidant, Antiinflammatory and Antiapoptotic Effects of Lycopene in Rats With Vancomycin‐Induced Nephrotoxicity	58
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Antibiotic treatment of community‐acquired pneumonia: A questionnaire survey in Danish general practice	43
Incidence in pharmacoepidemiology—Basic definitions and types of misclassification	36
Copper fabric improves the metabolic profile of obese mice: Potential role of the gut microbiota	32
Triangulation of pharmacoepidemiology and laboratory science to tackle otic quinolone safety	22
Involvement of the effect of renal hypoperfusion medications on vancomycin trough concentration: A secondary analysis using a retrospective observational data	22
Register‐based study on prescription renewal without the prescriber meeting the patient	22
Assessment of drug–drug interactions between moxonidine and antiepileptic drugs in the maximal electroshock seizure test in mice	22
A two‐decade review of butane toxicity as a substance of abuse	19
Clinical predictors of nephrotoxicity associated with teicoplanin: Meta‐analysis and meta‐regression	19
Efficacy of fibroblast growth factor 21 in non‐alcoholic fatty liver disease in guinea pigs	17
Matrix metalloproteinases are associated with severity of disease among COVID‐19 patients: A possible pharmacological target	17
Issue Information	16
Barriers and Facilitators to Pharmacist‐Led Deprescribing of Antihypertensives in Long‐Term Care: A Survey‐Based Study	16
Targeting of cancer cell death mechanisms by curcumin: Implications to cancer therapy	16
Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction	16
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How does deprescribing (not) reduce mortality? A review of a meta‐analysis in community‐dwelling older adults casts uncertainty over claimed benefits	15
The alleviatory effects of koumine on MSU‐induced gouty arthritis via the TLR4/NF‐κB/NLRP3 pathway	15

Sapanisertib attenuates pulmonary fibrosis by modulating Wnt5a/mTOR signalling	14
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A characterization of patients with low soluble urokinase plasminogen activator receptor who died within 90 days of hospital discharge	13
Vitamin D and SARS‐CoV‐2	13
Preclinical safety and biodistribution assessment of Ad‐KCNH2‐G628S administered via atrial painting in New Zealand white rabbits	13
Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats	13
Possible opioid‐saving effect of cannabis‐based medicine using individual‐based data from the Norwegian Prescription Database	13
Decreased blood pressure with acute administration of quercetin in L‐NAME‐induced hypertensive rats	12
Drug metabolism and drug transport of the 100 most prescribed oral drugs	12
Issue Information	12
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Medication use among the oldest old in the Faroe Islands—A national cross‐sectional study	12
The Patient Typology about deprescribing and medication‐related decisions: A quantitative exploration	12
Issue Information	12
Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications	12
Cytotoxicity, genotoxicity and mutagenicity of mixed ternary mononuclear Mg complex based on valproic acid with 1,10‐phenanthroline in Saccharomyces cerevisiae and V79 cells	12
Chronic mercury exposure induces oxidative stress in female rats by endothelial nitric oxide synthase uncoupling and cyclooxygenase‐2 activation, without affecting oestrogen receptor function	12
Risk of kidney injury in patients on concomitant oral vancomycin and piperacillin‐tazobactam: Analysis of the pharmacovigilance database in Japan	11
Leaky lessons learned: Efflux prone dopamine transporter variant reveals sex and circuit specific contributions of D2 receptor signalling to neuropsychiatric disease	11
Fluvoxamine Inhibited NLRP3 and NF‐κB Inflammatory Pathways and Maintained Genital Functions by Ameliorating CD‐MPR, KISS‐1, AQP4 and Claudin‐1 Expressions	11
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Effects of organic chemicals from diesel exhaust particles on adipocytes differentiated from human mesenchymal stem cells	11
Translational aspects of cytochrome P450‐mediated drug–drug interactions: A case study with clopidogrel	11
New Monitoring Recommendations for Digoxin During the Last Decade Are Associated With Decreased Serum Digoxin Concentrations in Patient Samples	11
Role of cytochrome P450 2C8 genetic polymorphism and epoxygenase uncoupling in periodontal remodelling affecting orthodontic treatment	11
Drugs targeting APOE4 that regulate beta‐amyloid aggregation in the brain: Therapeutic potential for Alzheimer's disease	11
Copper: From enigma to therapeutic target for neurological disorder	11
Increased Mitochondrial Superoxide Level Is Partially Associated With Vemurafenib‐Induced Renal Tubular Toxicity	11
Liquiritigenin‐Rich Hydroalcoholic Extract of Brazilian Red Propolis Reduces Dyskinesia Induced by 3,4‐ Dihydroxyphenylalanine in Hemiparkinsonian Rats	10
Corrigendum	10
Metabolism studies of 4′Cl‐CUMYL‐PINACA, 4′F‐CUMYL‐5F‐PINACA and 4′F‐CUMYL‐5F‐PICA using human hepatocytes and LC‐QTOF‐MS analysis	10
A novel flowchart to predict mortality and analyse effectiveness of routinely used pharmacological regimens in paraquat poisoning	10
Prescribing and deprescribing trends in schizophrenia: An overview of inpatients in Belgium and in the Canadian province of Québec	10
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Potential drug‐drug interactions in acute poisonings managed in the intensive care unit: Occurrence, risk factors and relationship to patient severity on admission	9
Further perspectives on statin use in patients with chronic kidney disease	9
The Role of Hydroxychloroquine in the Management of Rheumatic Disorders: A Comprehensive Review	9
Review of the Delay of Chronic Kidney Disease Progression by Wuling San on Improving Renal Fibrosis	9
Pro‐inflammatory cytokines/chemokines, TNF‐α, IL‐6 and MCP‐1, as biomarkers for the nephro‐ and pneumoprotective effect of silibinin after hepatic ischemia/reperfusion: Confirmation by immunohistochem	9
Exosomal lncRNA HOTAIR promotes osteoclast differentiation by targeting TGF‐β/PTHrP/RANKL pathway	9
The stimulant cathine from Khat causes tachycardia indirectly in the rat	9
Letter from the editor	9
Issue Information	9
Role of bradykinin and prostaglandin EP4 receptors in regulating TRPV1 channel sensitization in rat dorsal root ganglion neurons	9
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ChatGPT: First glance from a perspective of clinical pharmacology	9
Effects of Zuojin Pill (Rhizoma CoptidisandFructus Evodiaepreparation) on the pharmacokinetics and side effects of venlafaxine in humans	9
Issue Information	9
Issue Information	9
Effects of quercetin on ovarian function and regulation of the ovarian PI3K/Akt/FoxO3a signalling pathway and oxidative stress in a rat model of cyclophosphamide‐induced premature ovarian failure	9

Advancing deprescribing: Learnings from the first international conference on deprescribing	8
The state of deprescribing research: How did we get here?	8
Issue Information	8
First‐in‐human study with ACT‐1014‐6470, a novel oral complement factor 5a receptor 1 (C5aR1) antagonist, supported by pharmacokinetic predictions from animals to patients	8
BCPT 2024 Prizes and Awards	8
Ameliorative Role of β‐Caryophyllene on Antioxidant Biomarkers in a Paroxetine‐Induced Model of Male Sexual Dysfunction	8
Deprescribing in primary care without deterioration of health‐related outcomes: A real‐life, quality improvement project	8
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Optimizing autophagy modulation for enhanced TRAIL‐mediated therapy: Unveiling the superiority of late‐stage inhibition over early‐stage inhibition to overcome therapy resistance in cancer	8
Assessment of Rivaroxaban Plasma Concentration Using Chromogenic Anti‐Xa Assays and UHPLC–MS/MS in Chinese Patients With Atrial Fibrillation	8
Inappropriate polypharmacy management versus deprescribing: A review on their relationship	8
Correction to Involvement of H2S, NO and BDNF‐TrkB signalling pathway in the protective effects of simvastatin against pentylenetetrazole‐induced kindling and cognitive impairments in mice	8
Effect of dexmedetomidine on oxytocin‐induced uterine contraction during optimal caesarean section anaesthesia	8
Effects of GLP‐1 Receptor Agonists in Alcohol Use Disorder	8
Dose safety and pharmacodynamics of subcutaneous bupivacaine in a novel extended‐release microparticle formulation: A phase 1, dose‐ascending study in male volunteers	7
Changes in oral corticosteroid use in asthma treatment—A 20‐year Danish nationwide drug utilisation study	7
Issue Information	7
‘This Is My Decision’: A Qualitative Study of Individuals' Perspectives on Use of Semaglutide for Weight Loss	7
Issue Information	7
Disease activity and therapeutic drug monitoring of polyglutamates of methotrexate after daily or weekly administration of low‐dose methotrexate in patients recently diagnosed with rheumatoid arthriti	7
In vitro effect of hyoscine‐N‐butyl bromide and diclofenac sodium in human tuba uterina	7
Persistence to statin treatment: A cohort study in Lithuania	7
Four weeks SGLT2 inhibition improves beta cell function and glucose tolerance without affecting muscle free fatty acid or glucose uptake in subjects with type 2 diabetes	7
The Molecular and Clinical Impact of Atorvastatin Exposure on Paclitaxel Neurotoxicity in Sensory Neurons and Cancer Patients	7
Individual susceptibility has a major impact on strong association between oxidative stress, defence systems and Parkinson's disease	7
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Somatostatin receptor ligands suppressed proliferation and lipogenesis in 3T3‐L1 preadipocytes	7
Mechanistic insights into the pathogenesis of microtubule‐targeting agent‐induced peripheral neuropathy from pharmacogenetic and functional studies	7
Issue Information	7
Making it happen: Development of an interprofessional deprescribing education programme	7
Deaths caused by medication in persons not using illicit narcotic drugs: An autopsy study from Western Denmark	6
Downregulation of GPR160 inhibits the progression of glioma through suppressing epithelial to mesenchymal transition (EMT) biomarkers	6
Issue Information	6
Methylophiopogonanone A is a naturally occurring broad‐spectrum inhibitor against human UDP‐glucuronosyltransferases: Inhibition behaviours and implication in herb‐drug interactions	6
Berberine regulates pulmonary inflammatory microenvironment and decreases collagen deposition in response to bleomycin‐induced pulmonary fibrosis in mice	6
Dementia and neurodegenerative diseases: What is known and what is promising at the cellular and molecular level	6
Studies on the mode of action of synthetic diindolylmethane derivatives against triple negative breast cancer cells	6
Corrigendum	6
Multiple regulation and targeting effects of borneol in the neurovascular unit in neurodegenerative diseases	6
Effects of rifampicin on porphyrin metabolism in healthy volunteers	6
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Erratum	6
Issue Information	6
Growth differentiation factor 15 is dispensable for acetaminophen‐induced liver injury in mice	6
Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high‐grade serous ovarian cancer	6
Paroxetine alleviates ulcerative colitis in mice via restoring intestinal microbiota homeostasis and metabolism	6
Effect of stearyl alcohol on imiquimod‐induced psoriasis‐like skin inflammation in mice	6
Efficacy of weekly versus daily cholecalciferol for repleting serum vitamin D (25(OH)D) deficiency: A systematic review and meta‐analysis of randomized controlled trials	6
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Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease	6
Pharmacokinetics of free and total mycophenolic acid in paediatric and adult renal transplant recipients: Exploratory analysis of the effects of clinical factors and gene variants	6
Therapeutic benefit of melatonin in 5‐fluorouracil‐induced renal and hepatic injury	6
Antitumour effect of odoroside A and its derivative on human leukaemia cells through the ROS/JNK pathway	5
Initiation of Anticoagulants During the COVID‐19 Pandemic in Sweden: An Interrupted Time Series Analysis	5
Atenolol and mortality events in patients with chronic kidney disease: Analysis of data from the Japanese Adverse Drug Event Report database	5
Categorization of deprescribing communication tools: A scoping review	5
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Ten deprescribing articles you should know about: A guide for newcomers to the field	5
Healthcare Providers' Perspectives on Antidepressant Discontinuation: A Focus Group Study	5
Application of Artificial Intelligence in the Development of Traditional Chinese Medicine	5
Foetal Exposure to Phthalates and Endocrine Effects on the Leydig Cell	5
Emergency Department Visits due to Medication Overdose in a Finnish University Hospital	5
Study of the mechanism underlying the role of PINK1/Parkin in the formic acid‐induced autophagy of PC12 cells	5
Behavioural interaction of pyrazoloquinolinone positive allosteric modulators at α6GABAA receptors and diazepam in rats: Anti‐diazepam‐induced ataxia action as a structure‐dependent feature	5
Issue Information	5
Bruceine A Inhibits Cell Proliferation by Targeting the USP13/PARP1 Signalling Pathway in Multiple Myeloma	5
Biomarkers of Parkinson's disease in perspective of early diagnosis and translation of neurotrophic therapies	5
Issue Information	5
Welcome to Basic & Clinical Pharmacology & Toxicology 2024	5
High Throughput Pharmacovigilance Screening for Roflumilast Adverse Effects in Real‐World Settings: A Sequence Symmetry Analysis	5
The Pathobiology of Cerebrovascular Lesions in CADASIL Small Vessel Disease	5
Triptolide alleviates collagen‐induced arthritis in mice by modulating Treg/Th17 imbalance through the JAK/PTEN‐STAT3 pathway	5
Association between patient attitudes towards deprescribing and subsequent prescription changes	5
Investigating the P53‐dependent anti‐cancer effect of ibutamoren in human cancer cell lines	5
Phase I clinical trial evaluating the safety, tolerance, pharmacokinetics and pharmacodynamics of HSK21542 injection in healthy volunteers	5
Issue Information	5
Eugenol Alleviates Cerebral Ischemia–Reperfusion Injury in Mice by Promoting the Phagocytosis of Microglia via Up‐Regulating Tripartite Motif Protein 59	5
LW‐AFC Protects Against Neurological and Neuropsychiatric Effects of SARS‐CoV‐2 Spike Protein in Mice	5

Exploratory pharmacovigilance with machine learning in big patient data: A focused scoping review	5
A review on the new age methodologies for early detection of Alzheimer's and Parkinson's disease	5
Traditional Chinese Medicine for Inhibiting Ferroptosis in Ischemic‐Related Diseases	5
The effectiveness and safety of botulinum toxin injections for managing motor disorders of patients with Parkinson's disease: A meta‐analysis of randomized controlled trials	5
Plasma NGAL, suPAR, KIM‐1 and GDF‐15 for Improving Glomerular Filtration Rate Estimation in Older Hospitalized Patients	5
The role of decision tree and machine learning models for outcome prediction of bupropion exposure: A nationwide analysis of more than 14 000 patients in the United States	5
Limited sampling approach for model‐informed precision dosing of daptomycin to rapidly achieving the target area under the concentration‐time curve: A simulation study	5