Basic & Clinical Pharmacology & Toxicology

Article	Citations
Issue Information	263
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Incidence in pharmacoepidemiology—Basic definitions and types of misclassification	64
Matrix metalloproteinases are associated with severity of disease among COVID‐19 patients: A possible pharmacological target	58
Copper fabric improves the metabolic profile of obese mice: Potential role of the gut microbiota	58
How does deprescribing (not) reduce mortality? A review of a meta‐analysis in community‐dwelling older adults casts uncertainty over claimed benefits	37
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A two‐decade review of butane toxicity as a substance of abuse	24
Efficacy of fibroblast growth factor 21 in non‐alcoholic fatty liver disease in guinea pigs	24
Lithium and the risk of chronic kidney disease: A population‐based case–control study	23
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Register‐based study on prescription renewal without the prescriber meeting the patient	21
Electrochemical Point‐of‐Care Test for Assessing Serum Paracetamol Concentration: Comparison With Traditional Methods and Detection of Concomitant Drugs	21
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The Pharmacokinetics, Pharmacological Mechanisms and Clinical Application of Zhenwu Decoction	20
Antioxidant, Antiinflammatory and Antiapoptotic Effects of Lycopene in Rats With Vancomycin‐Induced Nephrotoxicity	19
Barriers and Facilitators to Pharmacist‐Led Deprescribing of Antihypertensives in Long‐Term Care: A Survey‐Based Study	19
Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction	18
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Artesunate alleviates intracerebral haemorrhage secondary injury by inducing ferroptosis in M1‐polarized microglia and suppressing inflammation through AMPK/mTORC1/GPX4 pathway	18
Medication use among the oldest old in the Faroe Islands—A national cross‐sectional study	18
Patients' Attitudes Towards Deprescribing Differ Across Specific Cardiovascular and Diabetes Medication: A Survey Study Assessing Within‐Patient Differences	18
Vitamin D and SARS‐CoV‐2	17
A characterization of patients with low soluble urokinase plasminogen activator receptor who died within 90 days of hospital discharge	17

Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats	16
Drug metabolism and drug transport of the 100 most prescribed oral drugs	16
Decreased blood pressure with acute administration of quercetin in L‐NAME‐induced hypertensive rats	16
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The Patient Typology about deprescribing and medication‐related decisions: A quantitative exploration	15
Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications	15
The Incidence of Benzodiazepine and Benzodiazepine‐Related Drug Use in People With and Without Parkinson's Disease—A Nationwide Cohort Study	14
Cytotoxicity, genotoxicity and mutagenicity of mixed ternary mononuclear Mg complex based on valproic acid with 1,10‐phenanthroline in Saccharomyces cerevisiae and V79 cells	14
Sapanisertib attenuates pulmonary fibrosis by modulating Wnt5a/mTOR signalling	14
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Preclinical safety and biodistribution assessment of Ad‐KCNH2‐G628S administered via atrial painting in New Zealand white rabbits	13
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Increased Mitochondrial Superoxide Level Is Partially Associated With Vemurafenib‐Induced Renal Tubular Toxicity	13
The alleviatory effects of koumine on MSU‐induced gouty arthritis via the TLR4/NF‐κB/NLRP3 pathway	13
New Monitoring Recommendations for Digoxin During the Last Decade Are Associated With Decreased Serum Digoxin Concentrations in Patient Samples	12
Prescribing and deprescribing trends in schizophrenia: An overview of inpatients in Belgium and in the Canadian province of Québec	12
Leaky lessons learned: Efflux prone dopamine transporter variant reveals sex and circuit specific contributions of D2 receptor signalling to neuropsychiatric disease	12
Effects of organic chemicals from diesel exhaust particles on adipocytes differentiated from human mesenchymal stem cells	12
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Metabolism studies of 4′Cl‐CUMYL‐PINACA, 4′F‐CUMYL‐5F‐PINACA and 4′F‐CUMYL‐5F‐PICA using human hepatocytes and LC‐QTOF‐MS analysis	12
Liquiritigenin‐Rich Hydroalcoholic Extract of Brazilian Red Propolis Reduces Dyskinesia Induced by 3,4‐ Dihydroxyphenylalanine in Hemiparkinsonian Rats	12
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Fluvoxamine Inhibited NLRP3 and NF‐κB Inflammatory Pathways and Maintained Genital Functions by Ameliorating CD‐MPR, KISS‐1, AQP4 and Claudin‐1 Expressions	11
Bergaptol Alleviates Oxidative Stress and Inflammation in Intracerebral Haemorrhage Mice via JAK2/STAT3 and NF‐κB Pathways, Improving Neurological Function	11
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The Role of Hydroxychloroquine in the Management of Rheumatic Disorders: A Comprehensive Review	11
Hyperfiltration and Metabolism Before and After a Low‐Calorie, Pre‐Gastric Bypass Surgery Diet: Significance for Concentrations of Hydrophilic and Lipophilic Drugs	11
Copper: From enigma to therapeutic target for neurological disorder	11
Significant Antispastic Effect of Combined Fasudil and Isosorbide Dinitrate on Internal Mammary Artery in Coronary Artery Bypass Grafting	11
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The stimulant cathine from Khat causes tachycardia indirectly in the rat	11
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Drugs targeting APOE4 that regulate beta‐amyloid aggregation in the brain: Therapeutic potential for Alzheimer's disease	11
Further perspectives on statin use in patients with chronic kidney disease	11
ChatGPT: First glance from a perspective of clinical pharmacology	11
Review of the Delay of Chronic Kidney Disease Progression by Wuling San on Improving Renal Fibrosis	11
Issue Information	10
BCPT 2024 Prizes and Awards	10
Advancing deprescribing: Learnings from the first international conference on deprescribing	10
First‐in‐human study with ACT‐1014‐6470, a novel oral complement factor 5a receptor 1 (C5aR1) antagonist, supported by pharmacokinetic predictions from animals to patients	10
Exosomal lncRNA HOTAIR promotes osteoclast differentiation by targeting TGF‐β/PTHrP/RANKL pathway	10
Deprescribing in primary care without deterioration of health‐related outcomes: A real‐life, quality improvement project	10
Inappropriate polypharmacy management versus deprescribing: A review on their relationship	10
Issue Information	10
CYP2D6 Copy Number Variations Identified by KASP PCR	10
Role of bradykinin and prostaglandin EP4 receptors in regulating TRPV1 channel sensitization in rat dorsal root ganglion neurons	10
Pro‐inflammatory cytokines/chemokines, TNF‐α, IL‐6 and MCP‐1, as biomarkers for the nephro‐ and pneumoprotective effect of silibinin after hepatic ischemia/reperfusion: Confirmation by immunohistochem	10
The state of deprescribing research: How did we get here?	10

Effects of Zuojin Pill (Rhizoma CoptidisandFructus Evodiaepreparation) on the pharmacokinetics and side effects of venlafaxine in humans	10
Assessment of Rivaroxaban Plasma Concentration Using Chromogenic Anti‐Xa Assays and UHPLC–MS/MS in Chinese Patients With Atrial Fibrillation	9
Effects of GLP‐1 Receptor Agonists in Alcohol Use Disorder	9
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BCPT 2025 Prizes and Awards	9
Optimizing autophagy modulation for enhanced TRAIL‐mediated therapy: Unveiling the superiority of late‐stage inhibition over early‐stage inhibition to overcome therapy resistance in cancer	9
Ameliorative Role of β‐Caryophyllene on Antioxidant Biomarkers in a Paroxetine‐Induced Model of Male Sexual Dysfunction	9
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Development of an Artificial Intelligence Powered Medication Risk Score Calculator Application	9
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Effect of dexmedetomidine on oxytocin‐induced uterine contraction during optimal caesarean section anaesthesia	9
Correction to Involvement of H2S, NO and BDNF‐TrkB signalling pathway in the protective effects of simvastatin against pentylenetetrazole‐induced kindling and cognitive impairments in mice	8
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Four weeks SGLT2 inhibition improves beta cell function and glucose tolerance without affecting muscle free fatty acid or glucose uptake in subjects with type 2 diabetes	8
‘This Is My Decision’: A Qualitative Study of Individuals' Perspectives on Use of Semaglutide for Weight Loss	8
Somatostatin receptor ligands suppressed proliferation and lipogenesis in 3T3‐L1 preadipocytes	8
The Molecular and Clinical Impact of Atorvastatin Exposure on Paclitaxel Neurotoxicity in Sensory Neurons and Cancer Patients	8
Dose safety and pharmacodynamics of subcutaneous bupivacaine in a novel extended‐release microparticle formulation: A phase 1, dose‐ascending study in male volunteers	8
Disease activity and therapeutic drug monitoring of polyglutamates of methotrexate after daily or weekly administration of low‐dose methotrexate in patients recently diagnosed with rheumatoid arthriti	8
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In vitro effect of hyoscine‐N‐butyl bromide and diclofenac sodium in human tuba uterina	8
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Making it happen: Development of an interprofessional deprescribing education programme	8
Questions in Healthcare Specifically Related to the Discipline of Pharmacy: A Descriptive Analysis of Queries to Drug Information Centres in Sweden	8
Paroxetine alleviates ulcerative colitis in mice via restoring intestinal microbiota homeostasis and metabolism	7
Efficacy of weekly versus daily cholecalciferol for repleting serum vitamin D (25(OH)D) deficiency: A systematic review and meta‐analysis of randomized controlled trials	7
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Downregulation of GPR160 inhibits the progression of glioma through suppressing epithelial to mesenchymal transition (EMT) biomarkers	7
Effect of stearyl alcohol on imiquimod‐induced psoriasis‐like skin inflammation in mice	7
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Dementia and neurodegenerative diseases: What is known and what is promising at the cellular and molecular level	7
Facilitating the Implementation of Physician‐Led Medication Reviews for Patients With Severe Mental Disorder and Diabetes: A Cost‐Minimization Analysis	7
Persistence to statin treatment: A cohort study in Lithuania	7
Erratum	7
Special Collection: Mechanisms of Vasodilatation Endothelium‐Dependent Hyperpolarization (MOVD/EDH2024)	7
Berberine regulates pulmonary inflammatory microenvironment and decreases collagen deposition in response to bleomycin‐induced pulmonary fibrosis in mice	6
Development of a Deprescribing Intervention for Proton Pump Inhibitors in Primary Care: A Co‐Design Approach With General Practitioners and Patients	6
Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease	6
Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high‐grade serous ovarian cancer	6
Exploratory pharmacovigilance with machine learning in big patient data: A focused scoping review	6
Application of Artificial Intelligence in the Development of Traditional Chinese Medicine	6
Growth differentiation factor 15 is dispensable for acetaminophen‐induced liver injury in mice	6
The Effects of Drugs on CYP3A Enzyme Activity and Protein Expression Through Ubiquitination Modification Regulation	6
Welcome to Basic & Clinical Pharmacology & Toxicology 2024	6
Corrigendum	6
Effects of rifampicin on porphyrin metabolism in healthy volunteers	6
Gadoteric Acid Induces Dose‐Dependent DNA Damage and Enzyme Binding in Fibroblast Cells	6
Correction to ‘β‐LAPachone Ameliorates Doxorubicin‐Induced Cardiotoxicity via Regulating Autophagy and Nrf2 Signalling Pathways in Mice’	6
Therapeutic benefit of melatonin in 5‐fluorouracil‐induced renal and hepatic injury	6
Foetal Exposure to Phthalates and Endocrine Effects on the Leydig Cell	6
High Throughput Pharmacovigilance Screening for Roflumilast Adverse Effects in Real‐World Settings: A Sequence Symmetry Analysis	6
The Pathobiology of Cerebrovascular Lesions in CADASIL Small Vessel Disease	6
Pharmacokinetics of free and total mycophenolic acid in paediatric and adult renal transplant recipients: Exploratory analysis of the effects of clinical factors and gene variants	6
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From Hospital to Home: Patient Experiences With Medication Counselling for Colorectal Cancer	6
The effectiveness and safety of botulinum toxin injections for managing motor disorders of patients with Parkinson's disease: A meta‐analysis of randomized controlled trials	6
Ten deprescribing articles you should know about: A guide for newcomers to the field	6
A review on the new age methodologies for early detection of Alzheimer's and Parkinson's disease	6
Healthcare Providers' Perspectives on Antidepressant Discontinuation: A Focus Group Study	6
Studies on the mode of action of synthetic diindolylmethane derivatives against triple negative breast cancer cells	6
Traditional Chinese Medicine for Inhibiting Ferroptosis in Ischemic‐Related Diseases	6
Deaths caused by medication in persons not using illicit narcotic drugs: An autopsy study from Western Denmark	6
Association between patient attitudes towards deprescribing and subsequent prescription changes	5
Biomarkers of Parkinson's disease in perspective of early diagnosis and translation of neurotrophic therapies	5
Limited sampling approach for model‐informed precision dosing of daptomycin to rapidly achieving the target area under the concentration‐time curve: A simulation study	5
Plasma NGAL, suPAR, KIM‐1 and GDF‐15 for Improving Glomerular Filtration Rate Estimation in Older Hospitalized Patients	5
The BCPT young researcher Nordic Prize 2022 goes to Associate Professor Tore Bjerregaard Stage	5
Gastroprotective effect of sumatriptan against indomethacin‐, stress‐ and ethanol‐induced gastric damage in male rats: Possible modulatory role of 5‐hydroxytryptamine 1B/1D receptors and pro‐inflammat	5
Behavioural interaction of pyrazoloquinolinone positive allosteric modulators at α6GABAA receptors and diazepam in rats: Anti‐diazepam‐induced ataxia action as a structure‐dependent feature	5
Phase I clinical trial evaluating the safety, tolerance, pharmacokinetics and pharmacodynamics of HSK21542 injection in healthy volunteers	5
Issue Information	5
Study of the mechanism underlying the role of PINK1/Parkin in the formic acid‐induced autophagy of PC12 cells	5
Bruceine A Inhibits Cell Proliferation by Targeting the USP13/PARP1 Signalling Pathway in Multiple Myeloma	5
LW‐AFC Protects Against Neurological and Neuropsychiatric Effects of SARS‐CoV‐2 Spike Protein in Mice	5
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Triptolide alleviates collagen‐induced arthritis in mice by modulating Treg/Th17 imbalance through the JAK/PTEN‐STAT3 pathway	5
CYP3A4*22 and bleeding risk in ticagrelor users	5
Should high‐dose N‐acetylcysteine be given in cases of massive paracetamol overdoses: A narrative review	5
Ribavirin inhibits cell proliferation and metastasis and prolongs survival in soft tissue sarcomas by downregulating both protein arginine methyltransferases 1 and 5	5
The effects of cannabidiol against Methotrexate‐induced lung damage	5
Optimal dosing of gliclazide—A model‐based approach	5
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Vancomycin audit in the paediatric population: Patterns of use and appropriateness of therapeutic drug monitoring	5
The role of decision tree and machine learning models for outcome prediction of bupropion exposure: A nationwide analysis of more than 14 000 patients in the United States	5
Emergency Department Visits due to Medication Overdose in a Finnish University Hospital	5
Multi‐Target Renal Protection of Wine‐Processed Polygonatum sibiricum Against Cisplatin‐Induced Nephrotoxicity: Integrated Phytochemistry, Network Pharmacology and Experimental Valid	5
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Disease‐modifying therapies in multiple sclerosis: A focused review of rituximab	5
Initiation of Anticoagulants During the COVID‐19 Pandemic in Sweden: An Interrupted Time Series Analysis	5
Blood Pressure–Lowering Effects of Aldosterone Synthase Inhibitors—A Systematic Review	5
Eugenol Alleviates Cerebral Ischemia–Reperfusion Injury in Mice by Promoting the Phagocytosis of Microglia via Up‐Regulating Tripartite Motif Protein 59	5
α‐Lipoic acid up‐regulates gene expression but reduces protein levels of fibroblast growth factor 21 in HepG2 cells	5
Direct oral anticoagulant concentrations and adherence in stroke patients	5
Adverse effects of an aldosterone synthase (CYP11B2) inhibitor, fadrozole (FAD286), on inflamed rat colon	5
Categorization of deprescribing communication tools: A scoping review	5
Investigating the P53‐dependent anti‐cancer effect of ibutamoren in human cancer cell lines	5
Atenolol and mortality events in patients with chronic kidney disease: Analysis of data from the Japanese Adverse Drug Event Report database	5