Basic & Clinical Pharmacology & Toxicology

Article	Citations
Issue Information	245
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Incidence in pharmacoepidemiology—Basic definitions and types of misclassification	74
Copper fabric improves the metabolic profile of obese mice: Potential role of the gut microbiota	61
Matrix metalloproteinases are associated with severity of disease among COVID‐19 patients: A possible pharmacological target	55
Antioxidant, Antiinflammatory and Antiapoptotic Effects of Lycopene in Rats With Vancomycin‐Induced Nephrotoxicity	54
How does deprescribing (not) reduce mortality? A review of a meta‐analysis in community‐dwelling older adults casts uncertainty over claimed benefits	37
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Barriers and Facilitators to Pharmacist‐Led Deprescribing of Antihypertensives in Long‐Term Care: A Survey‐Based Study	24
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Register‐based study on prescription renewal without the prescriber meeting the patient	23
Efficacy of fibroblast growth factor 21 in non‐alcoholic fatty liver disease in guinea pigs	23
Lithium and the risk of chronic kidney disease: A population‐based case–control study	21
Role of Inflammatory and Proresolving Mediators in Endothelial Dysfunction	21
Artesunate alleviates intracerebral haemorrhage secondary injury by inducing ferroptosis in M1‐polarized microglia and suppressing inflammation through AMPK/mTORC1/GPX4 pathway	19
Electrochemical Point‐of‐Care Test for Assessing Serum Paracetamol Concentration: Comparison With Traditional Methods and Detection of Concomitant Drugs	19
A two‐decade review of butane toxicity as a substance of abuse	18
Patients' Attitudes Towards Deprescribing Differ Across Specific Cardiovascular and Diabetes Medication: A Survey Study Assessing Within‐Patient Differences	18
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Vitamin D and SARS‐CoV‐2	17
Medication use among the oldest old in the Faroe Islands—A national cross‐sectional study	17
Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats	17
A characterization of patients with low soluble urokinase plasminogen activator receptor who died within 90 days of hospital discharge	17
Methadone pharmacokinetics in opioid agonist treatment: Influencing factors and clinical implications	16

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The Patient Typology about deprescribing and medication‐related decisions: A quantitative exploration	15
Cytotoxicity, genotoxicity and mutagenicity of mixed ternary mononuclear Mg complex based on valproic acid with 1,10‐phenanthroline in Saccharomyces cerevisiae and V79 cells	15
Sapanisertib attenuates pulmonary fibrosis by modulating Wnt5a/mTOR signalling	15
Preclinical safety and biodistribution assessment of Ad‐KCNH2‐G628S administered via atrial painting in New Zealand white rabbits	14
Decreased blood pressure with acute administration of quercetin in L‐NAME‐induced hypertensive rats	14
Drug metabolism and drug transport of the 100 most prescribed oral drugs	14
The Incidence of Benzodiazepine and Benzodiazepine‐Related Drug Use in People With and Without Parkinson's Disease—A Nationwide Cohort Study	14
The alleviatory effects of koumine on MSU‐induced gouty arthritis via the TLR4/NF‐κB/NLRP3 pathway	14
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Prescribing and deprescribing trends in schizophrenia: An overview of inpatients in Belgium and in the Canadian province of Québec	13
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Liquiritigenin‐Rich Hydroalcoholic Extract of Brazilian Red Propolis Reduces Dyskinesia Induced by 3,4‐ Dihydroxyphenylalanine in Hemiparkinsonian Rats	13
Increased Mitochondrial Superoxide Level Is Partially Associated With Vemurafenib‐Induced Renal Tubular Toxicity	13
New Monitoring Recommendations for Digoxin During the Last Decade Are Associated With Decreased Serum Digoxin Concentrations in Patient Samples	12
Metabolism studies of 4′Cl‐CUMYL‐PINACA, 4′F‐CUMYL‐5F‐PINACA and 4′F‐CUMYL‐5F‐PICA using human hepatocytes and LC‐QTOF‐MS analysis	12
Copper: From enigma to therapeutic target for neurological disorder	12
Effects of organic chemicals from diesel exhaust particles on adipocytes differentiated from human mesenchymal stem cells	12
Leaky lessons learned: Efflux prone dopamine transporter variant reveals sex and circuit specific contributions of D2 receptor signalling to neuropsychiatric disease	12
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Drugs targeting APOE4 that regulate beta‐amyloid aggregation in the brain: Therapeutic potential for Alzheimer's disease	11
Further perspectives on statin use in patients with chronic kidney disease	11
Effects of Zuojin Pill (Rhizoma CoptidisandFructus Evodiaepreparation) on the pharmacokinetics and side effects of venlafaxine in humans	11
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Fluvoxamine Inhibited NLRP3 and NF‐κB Inflammatory Pathways and Maintained Genital Functions by Ameliorating CD‐MPR, KISS‐1, AQP4 and Claudin‐1 Expressions	11
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The stimulant cathine from Khat causes tachycardia indirectly in the rat	11
Review of the Delay of Chronic Kidney Disease Progression by Wuling San on Improving Renal Fibrosis	11
Bergaptol Alleviates Oxidative Stress and Inflammation in Intracerebral Haemorrhage Mice via JAK2/STAT3 and NF‐κB Pathways, Improving Neurological Function	11
Potential drug‐drug interactions in acute poisonings managed in the intensive care unit: Occurrence, risk factors and relationship to patient severity on admission	11
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The Role of Hydroxychloroquine in the Management of Rheumatic Disorders: A Comprehensive Review	11
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Exosomal lncRNA HOTAIR promotes osteoclast differentiation by targeting TGF‐β/PTHrP/RANKL pathway	10
Ameliorative Role of β‐Caryophyllene on Antioxidant Biomarkers in a Paroxetine‐Induced Model of Male Sexual Dysfunction	10
Effect of dexmedetomidine on oxytocin‐induced uterine contraction during optimal caesarean section anaesthesia	10
ChatGPT: First glance from a perspective of clinical pharmacology	10
Effects of quercetin on ovarian function and regulation of the ovarian PI3K/Akt/FoxO3a signalling pathway and oxidative stress in a rat model of cyclophosphamide‐induced premature ovarian failure	10
BCPT 2024 Prizes and Awards	10
Role of bradykinin and prostaglandin EP4 receptors in regulating TRPV1 channel sensitization in rat dorsal root ganglion neurons	10
CYP2D6 Copy Number Variations Identified by KASP PCR	10
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Deprescribing in primary care without deterioration of health‐related outcomes: A real‐life, quality improvement project	10
Letter from the editor	10
Pro‐inflammatory cytokines/chemokines, TNF‐α, IL‐6 and MCP‐1, as biomarkers for the nephro‐ and pneumoprotective effect of silibinin after hepatic ischemia/reperfusion: Confirmation by immunohistochem	9
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Development of an Artificial Intelligence Powered Medication Risk Score Calculator Application	9
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First‐in‐human study with ACT‐1014‐6470, a novel oral complement factor 5a receptor 1 (C5aR1) antagonist, supported by pharmacokinetic predictions from animals to patients	9
Inappropriate polypharmacy management versus deprescribing: A review on their relationship	9
Optimizing autophagy modulation for enhanced TRAIL‐mediated therapy: Unveiling the superiority of late‐stage inhibition over early‐stage inhibition to overcome therapy resistance in cancer	9
Effects of GLP‐1 Receptor Agonists in Alcohol Use Disorder	9
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Assessment of Rivaroxaban Plasma Concentration Using Chromogenic Anti‐Xa Assays and UHPLC–MS/MS in Chinese Patients With Atrial Fibrillation	9
Advancing deprescribing: Learnings from the first international conference on deprescribing	9
The state of deprescribing research: How did we get here?	9
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The Molecular and Clinical Impact of Atorvastatin Exposure on Paclitaxel Neurotoxicity in Sensory Neurons and Cancer Patients	8
Dose safety and pharmacodynamics of subcutaneous bupivacaine in a novel extended‐release microparticle formulation: A phase 1, dose‐ascending study in male volunteers	8
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‘This Is My Decision’: A Qualitative Study of Individuals' Perspectives on Use of Semaglutide for Weight Loss	8
Somatostatin receptor ligands suppressed proliferation and lipogenesis in 3T3‐L1 preadipocytes	8
Disease activity and therapeutic drug monitoring of polyglutamates of methotrexate after daily or weekly administration of low‐dose methotrexate in patients recently diagnosed with rheumatoid arthriti	8
Correction to Involvement of H2S, NO and BDNF‐TrkB signalling pathway in the protective effects of simvastatin against pentylenetetrazole‐induced kindling and cognitive impairments in mice	8
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Making it happen: Development of an interprofessional deprescribing education programme	8
Questions in Healthcare Specifically Related to the Discipline of Pharmacy: A Descriptive Analysis of Queries to Drug Information Centres in Sweden	8
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In vitro effect of hyoscine‐N‐butyl bromide and diclofenac sodium in human tuba uterina	8
Persistence to statin treatment: A cohort study in Lithuania	8
Four weeks SGLT2 inhibition improves beta cell function and glucose tolerance without affecting muscle free fatty acid or glucose uptake in subjects with type 2 diabetes	8
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Effect of stearyl alcohol on imiquimod‐induced psoriasis‐like skin inflammation in mice	7
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Erratum	7
Efficacy of weekly versus daily cholecalciferol for repleting serum vitamin D (25(OH)D) deficiency: A systematic review and meta‐analysis of randomized controlled trials	7
Dementia and neurodegenerative diseases: What is known and what is promising at the cellular and molecular level	7
Berberine regulates pulmonary inflammatory microenvironment and decreases collagen deposition in response to bleomycin‐induced pulmonary fibrosis in mice	7
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Special Collection: Mechanisms of Vasodilatation Endothelium‐Dependent Hyperpolarization (MOVD/EDH2024)	7
Paroxetine alleviates ulcerative colitis in mice via restoring intestinal microbiota homeostasis and metabolism	7
Downregulation of GPR160 inhibits the progression of glioma through suppressing epithelial to mesenchymal transition (EMT) biomarkers	7
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Development of a Deprescribing Intervention for Proton Pump Inhibitors in Primary Care: A Co‐Design Approach With General Practitioners and Patients	7
Exploratory pharmacovigilance with machine learning in big patient data: A focused scoping review	6
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Foetal Exposure to Phthalates and Endocrine Effects on the Leydig Cell	6
Traditional Chinese Medicine for Inhibiting Ferroptosis in Ischemic‐Related Diseases	6
The Effects of Drugs on CYP3A Enzyme Activity and Protein Expression Through Ubiquitination Modification Regulation	6
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Growth differentiation factor 15 is dispensable for acetaminophen‐induced liver injury in mice	6
The effectiveness and safety of botulinum toxin injections for managing motor disorders of patients with Parkinson's disease: A meta‐analysis of randomized controlled trials	6
Correction to ‘β‐LAPachone Ameliorates Doxorubicin‐Induced Cardiotoxicity via Regulating Autophagy and Nrf2 Signalling Pathways in Mice’	6
Pharmacokinetics of free and total mycophenolic acid in paediatric and adult renal transplant recipients: Exploratory analysis of the effects of clinical factors and gene variants	6
Toxicity and therapy outcome associations in LIG3, SLCO1B3, ABCB1, OPRM1 and GSTP1 in high‐grade serous ovarian cancer	6
Effects of rifampicin on porphyrin metabolism in healthy volunteers	6
LW‐AFC Protects Against Neurological and Neuropsychiatric Effects of SARS‐CoV‐2 Spike Protein in Mice	6
Multi‐Target Renal Protection of Wine‐Processed Polygonatum sibiricum Against Cisplatin‐Induced Nephrotoxicity: Integrated Phytochemistry, Network Pharmacology and Experimental Valid	6
A review on the new age methodologies for early detection of Alzheimer's and Parkinson's disease	6
Association between patient attitudes towards deprescribing and subsequent prescription changes	6
Ten deprescribing articles you should know about: A guide for newcomers to the field	6
High Throughput Pharmacovigilance Screening for Roflumilast Adverse Effects in Real‐World Settings: A Sequence Symmetry Analysis	6
Welcome to Basic & Clinical Pharmacology & Toxicology 2024	6
Gentiopicroside Attenuated Dopaminergic Neurodegeneration via Inhibiting Neuroinflammatory Responses and Ferroptosis in Experimental Models of Parkinson's Disease	6
Corrigendum	6
Studies on the mode of action of synthetic diindolylmethane derivatives against triple negative breast cancer cells	6
Healthcare Providers' Perspectives on Antidepressant Discontinuation: A Focus Group Study	6
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Therapeutic benefit of melatonin in 5‐fluorouracil‐induced renal and hepatic injury	6
Deaths caused by medication in persons not using illicit narcotic drugs: An autopsy study from Western Denmark	6
Plasma NGAL, suPAR, KIM‐1 and GDF‐15 for Improving Glomerular Filtration Rate Estimation in Older Hospitalized Patients	6
The Pathobiology of Cerebrovascular Lesions in CADASIL Small Vessel Disease	6
Application of Artificial Intelligence in the Development of Traditional Chinese Medicine	6
Atenolol and mortality events in patients with chronic kidney disease: Analysis of data from the Japanese Adverse Drug Event Report database	5
Bruceine A Inhibits Cell Proliferation by Targeting the USP13/PARP1 Signalling Pathway in Multiple Myeloma	5
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Optimal dosing of gliclazide—A model‐based approach	5
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The effects of cannabidiol against Methotrexate‐induced lung damage	5
Behavioural interaction of pyrazoloquinolinone positive allosteric modulators at α6GABAA receptors and diazepam in rats: Anti‐diazepam‐induced ataxia action as a structure‐dependent feature	5
Direct oral anticoagulant concentrations and adherence in stroke patients	5
Disease‐modifying therapies in multiple sclerosis: A focused review of rituximab	5
Biomarkers of Parkinson's disease in perspective of early diagnosis and translation of neurotrophic therapies	5
Study of the mechanism underlying the role of PINK1/Parkin in the formic acid‐induced autophagy of PC12 cells	5
Eugenol Alleviates Cerebral Ischemia–Reperfusion Injury in Mice by Promoting the Phagocytosis of Microglia via Up‐Regulating Tripartite Motif Protein 59	5

The role of decision tree and machine learning models for outcome prediction of bupropion exposure: A nationwide analysis of more than 14 000 patients in the United States	5
Should high‐dose N‐acetylcysteine be given in cases of massive paracetamol overdoses: A narrative review	5
Carnosol attenuated atrophy of C2C12 myotubes induced by tumour‐derived exosomal miR‐183‐5p through inhibiting Smad3 pathway activation and keeping mitochondrial respiration	5
Gastroprotective effect of sumatriptan against indomethacin‐, stress‐ and ethanol‐induced gastric damage in male rats: Possible modulatory role of 5‐hydroxytryptamine 1B/1D receptors and pro‐inflammat	5
Blood Pressure–Lowering Effects of Aldosterone Synthase Inhibitors—A Systematic Review	5
Phase I clinical trial evaluating the safety, tolerance, pharmacokinetics and pharmacodynamics of HSK21542 injection in healthy volunteers	5
CYP3A4*22 and bleeding risk in ticagrelor users	5
Limited sampling approach for model‐informed precision dosing of daptomycin to rapidly achieving the target area under the concentration‐time curve: A simulation study	5
Categorization of deprescribing communication tools: A scoping review	5
Triptolide alleviates collagen‐induced arthritis in mice by modulating Treg/Th17 imbalance through the JAK/PTEN‐STAT3 pathway	5
Emergency Department Visits due to Medication Overdose in a Finnish University Hospital	5
Vancomycin audit in the paediatric population: Patterns of use and appropriateness of therapeutic drug monitoring	5
Adverse effects of an aldosterone synthase (CYP11B2) inhibitor, fadrozole (FAD286), on inflamed rat colon	5
The BCPT young researcher Nordic Prize 2022 goes to Associate Professor Tore Bjerregaard Stage	5
Ribavirin inhibits cell proliferation and metastasis and prolongs survival in soft tissue sarcomas by downregulating both protein arginine methyltransferases 1 and 5	5
Investigating the P53‐dependent anti‐cancer effect of ibutamoren in human cancer cell lines	5
α‐Lipoic acid up‐regulates gene expression but reduces protein levels of fibroblast growth factor 21 in HepG2 cells	5
Initiation of Anticoagulants During the COVID‐19 Pandemic in Sweden: An Interrupted Time Series Analysis	5
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