OOIR: Observatory of International Research

Papers

(The median citation count of Particle and Fibre Toxicology is 11. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Aryl hydrocarbon receptor activation-mediated vascular toxicity of ambient fine particulate matter: contribution of polycyclic aromatic hydrocarbons and osteopontin as a biomarker	207
Impact of in vitro digested zinc oxide nanoparticles on intestinal model systems	124
Toxicological inhalation studies in rats to substantiate grouping of zinc oxide nanoforms	122
Histopathology of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities in a murine model	120
Single-cell transcriptome sequencing–based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis	113
Impact of environmental microplastic exposure on HepG2 cells: unraveling proliferation, mitochondrial dynamics and autophagy activation	111
Lung function and self-rated symptoms in healthy volunteers after exposure to hydrotreated vegetable oil (HVO) exhaust with and without particles	80
Road tunnel-derived coarse, fine and ultrafine particulate matter: physical and chemical characterization and pro-inflammatory responses in human bronchial epithelial cells	62
Toxicokinetic study following intratracheal instillation or oral gavage of two [7Be]-tagged carbon black samples	62
Placental-fetal distribution of carbon particles in a pregnant rabbit model after repeated exposure to diluted diesel engine exhaust	60
An experimental study on lung deposition of inhaled 2 μm particles in relation to lung characteristics and deposition models	58
Exposure to ambient air pollution over developmental stages induced neurodevelopmental impairment in mice offspring via microbiome-gut-brain axis	57
Correction: Pulmonary effects of exposure to indium and its compounds: cross-sectional survey of exposed workers and experimental findings in rodents	50
Decidual derived exosomal miR-99a-5p targets Ppp2r5a to inhibit trophoblast invasion in response to CeO2NPs exposure	50
Polystyrene nanobeads exacerbate chronic colitis in mice involving in oxidative stress and hepatic lipid metabolism	48
Impact on murine neurodevelopment of early-life exposure to airborne ultrafine carbon nanoparticles	47
An investigation of the internal morphology of asbestos ferruginous bodies: constraining their role in the onset of malignant mesothelioma	43
Short- and long-term pathologic responses to quartz are induced by nearly free silanols formed during crystal fracturing	43
The pro-inflammatory effects of combined exposure to diesel exhaust particles and mineral particles in human bronchial epithelial cells	41
Acute phase response following pulmonary exposure to soluble and insoluble metal oxide nanomaterials in mice	41
Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils	37
Attenuation of PM2.5-induced alveolar epithelial cells and lung injury through regulation of mitochondrial fission and fusion	37
Acute airway inflammation following controlled biodiesel exhaust exposure in healthy subjects	34
Correction: Reduction of pulmonary toxicity of metal oxide nanoparticles by phosphonate-based surface passivation	33
ROS generation and p-38 activation contribute to montmorillonite-induced corneal toxicity in vitro and in vivo	32

Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley rats	30
Copper oxide nanoparticles trigger macrophage cell death with misfolding of Cu/Zn superoxide dismutase 1 (SOD1)	30
Establishing relationships between particle-induced in vitro and in vivo inflammation endpoints to better extrapolate between in vitro markers and in vivo fibrosis	30
A 90-day oral exposure to food-grade gold at relevant human doses impacts the gut microbiota and the local immune system in a sex-dependent manner in mice	30
Food-grade titanium dioxide and zinc oxide nanoparticles induce toxicity and cardiac damage after oral exposure in rats	29
Effective density of inhaled environmental and engineered nanoparticles and its impact on the lung deposition and dosimetry	28
Combined exposure to fine particulate matter and high glucose aggravates endothelial damage by increasing inflammation and mitophagy: the involvement of vitamin D	27
Dose–response relationship of pulmonary disorders by inhalation exposure to cross-linked water-soluble acrylic acid polymers in F344 rats	26
Exposure to combustion derived particulate matter exacerbates influenza infection in neonatal mice by inhibiting IL22 production	26
Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics	26
Neurometabolomic impacts of wood smoke and protective benefits of anti-aging therapeutics in aged female C57BL/6J mice	26
Airborne micro- and nanoplastics: emerging causes of respiratory diseases	26
Acute health effects of ambient air pollution including ultrafine particles in a semi-experimental setting in young, healthy individuals	25
Chronic effects of two rutile TiO2 nanomaterials in human intestinal and hepatic cell lines	25
Cerium dioxide nanoparticles coated with benzo[a]pyrene modify aryl hydrocarbon receptor activity, trophoblast differentiation and mitochondrial network phenotype in human placenta	25
Epithelial MAPK signaling directs endothelial NRF2 signaling and IL-8 secretion in a tri-culture model of the alveolar-microvascular interface following diesel exhaust particulate (DEP) exposure	24
Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM2.5-induced lung injury: a comparative study	24
Addressing the relevance of polystyrene nano- and microplastic particles used to support exposure, toxicity and risk assessment: implications and recommendations	24
Polystyrene nanoplastics exposure induces cognitive impairment in mice via induction of oxidative stress and ERK/MAPK-mediated neuronal cuproptosis	24
The discovery of regional neurotoxicity-associated metabolic alterations induced by carbon quantum dots in brain of mice using a spatial metabolomics analysis	24
Hazard assessment of nanomaterials: how to meet the requirements for (next generation) risk assessment	24
The potential involvement of inhaled iron (Fe) in the neurotoxic effects of ultrafine particulate matter air pollution exposure on brain development in mice	24
Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats	24
Circulatory metabolites trigger ex vivo arterial endothelial cell dysfunction in population chronically exposed to diesel exhaust	24
Combustion products of burn pit constituents induce more changes in asthmatic than non-asthmatic murine lungs	23
Long-term exposure to polystyrene microplastics triggers premature testicular aging	23
Ferroptosis contributing to cardiomyocyte injury induced by silica nanoparticles via miR-125b-2-3p/HO-1 signaling	23
Cellular response of keratinocytes to the entry and accumulation of nanoplastic particles	22
Particulate matter from car exhaust alters function of human iPSC-derived microglia	22
Derivation of first-order dissolution rates to estimate particle clearance and burden in the human respiratory tract	22
Murine in utero exposure to simulated complex urban air pollution disturbs offspring gut maturation and microbiota during intestinal suckling-to-weaning transition in a sex-dependent manner	22
Polystyrene nanoplastics with different functional groups and charges have different impacts on type 2 diabetes	21
Prenatal PM2.5 exposure impairs spatial learning and memory in male mice offspring: from transcriptional regulation to neuronal morphogenesis	21
Compositional and structural analysis of engineered stones and inorganic particles in silicotic nodules of exposed workers	21
Combustion-derived carbon nanoparticles cause delayed apoptosis in neutrophil-like HL-60 cells in vitro and in primed human neutrophilic granulocytes ex vivo	20
Aluminium oxide nanoparticles compromise spatial memory performance and proBDNF-mediated neuronal function in the hippocampus of rats	20
Influence of polyethylene terephthalate (PET) microplastic on selected active substances in the intramural neurons of the porcine duodenum	20
Genome-wide DNA methylation sequencing reveals the involvement of ferroptosis in hepatotoxicity induced by dietary exposure to food-grade titanium dioxide	20
Combining analytical techniques to assess the translocation of diesel particles across an alveolar tissue barrier in vitro	19
Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway	19
Understanding the toxicological effects of TiO2 nanoparticles extracted from sunscreens on human keratinocytes and skin explants	19
Diesel Exhaust Particle (DEP)-induced glucose intolerance is driven by an intestinal innate immune response and NLRP3 activation in mice	19
Difference in carcinogenicities of two different vapor grown carbon fibers with different physicochemical characteristics induced by intratracheal instillation in rats	19
The subacute toxicity and underlying mechanisms of biomimetic mesoporous polydopamine nanoparticles	18
Microplastics are associated with elevated atherosclerotic risk and increased vascular complexity in acute coronary syndrome patients	18
Putative adverse outcome pathways for silver nanoparticle toxicity on mammalian male reproductive system: a literature review	18
Polycyclic aromatic hydrocarbons in urban particle matter exacerbate movement disorder after ischemic stroke via potentiation of neuroinflammation	18
Amorphous silica nanoparticles cause abnormal cytokinesis and multinucleation through dysfunction of the centralspindlin complex and microfilaments	17
Chronic maternal exposure to titanium dioxide nanoparticles alters breathing in newborn offspring	17
Airway and systemic biomarkers of health effects after short-term exposure to indoor ultrafine particles from cooking and candles – A randomized controlled double-blind crossover study among mild asth	17

Results from omic approaches in rat or mouse models exposed to inhaled crystalline silica: a systematic review	17
Oral toxicological study of titanium dioxide nanoparticles with a crystallite diameter of 6 nm in rats	17
Exposure to high dose of polystyrene nanoplastics causes trophoblast cell apoptosis and induces miscarriage	16
Seasonal PM2.5 exposures induce differential responses to influenza A virus infection in primary human airway epithelial cells	16
Concentration-dependent increase in symptoms due to diesel exhaust in a controlled human exposure study	15
Controlled human exposures: a review and comparison of the health effects of diesel exhaust and wood smoke	15
Long-term PM2.5 exposure disrupts corneal epithelial homeostasis by impairing limbal stem/progenitor cells in humans and rat models	15
Immune consequences of exposure to β-pinene oxidation aerosols: adult versus gestational murine models	15
MMP-3-mediated cleavage of OPN is involved in copper oxide nanoparticle-induced activation of fibroblasts	14
Human exposure to diesel exhaust induces CYP1A1 expression and AhR activation without a coordinated antioxidant response	14
Correction: Perinatal foodborne titanium dioxide exposure-mediated dysbiosis predisposes mice to develop colitis through life	14
Biokinetics of subacutely co-inhaled same size gold and silver nanoparticles	13
Lung recovery from DNA damage induced by graphene oxide is dependent on size, dose and inflammation profile	13
Correction: Combining analytical techniques to assess the translocation of diesel particles across an alveolar tissue barrier in vitro	13
A novel in-situ method to determine the respiratory tract deposition of carbonaceous particles reveals dangers of public commuting in highly polluted megacity	13
Cell-nanoparticle stickiness and dose delivery in a multi-model in silico platform: DosiGUI	13
Systemic immunological responses are dependent on sex and ovarian hormone presence following acute inhaled woodsmoke exposure	13
Lung versus gut exposure to air pollution particles differentially affect metabolic health in mice	13
White matter pathology in alzheimer’s transgenic mice with chronic exposure to low-level ambient fine particulate matter	13
Controlled human exposure to diesel exhaust: results illuminate health effects of traffic-related air pollution and inform future directions	13
Propionic acid/FBP1 is involved in polystyrene nanoplastic-induced cardiac injury via the gut-heart axis	12
Correction: Central IKKβ Inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes	12
The importance of mineralogical composition for the cytotoxic and pro-inflammatory effects of mineral dust	12
Correction: a systematic quality evaluation and review of nanomaterial genotoxicity studies: a regulatory perspective	12
Short- and long-term polystyrene nano- and microplastic exposure promotes oxidative stress and divergently affects skin cell architecture and Wnt/beta-catenin signaling	11
Oxidative stress generated by polycyclic aromatic hydrocarbons from ambient particulate matter enhance vascular smooth muscle cell migration through MMP upregulation and actin reorganization	11
The application of existing genotoxicity methodologies for grouping of nanomaterials: towards an integrated approach to testing and assessment	11
A comprehensive understanding of ambient particulate matter and its components on the adverse health effects based from epidemiological and laboratory evidence	11
Fibrotic pulmonary dust foci is an advanced pneumoconiosis lesion in rats induced by titanium dioxide nanoparticles in a 2-year inhalation study	11
Pro-inflammatory effects of inhaled Great Salt Lake dust particles	11
Brain iron accumulation in neurodegenerative disorders: Does air pollution play a role?	11
Correction to: Dose–response relationship of pulmonary disorders by inhalation exposure to cross-linked water-soluble acrylic acid polymers in F344 rats	11