OOIR: Observatory of International Research

Papers

(The TQCC of Particle and Fibre Toxicology is 19. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Histopathology of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities in a murine model	301
Single-cell transcriptome sequencing–based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis	167
Lung function and self-rated symptoms in healthy volunteers after exposure to hydrotreated vegetable oil (HVO) exhaust with and without particles	103
Aryl hydrocarbon receptor activation-mediated vascular toxicity of ambient fine particulate matter: contribution of polycyclic aromatic hydrocarbons and osteopontin as a biomarker	96
Impact of in vitro digested zinc oxide nanoparticles on intestinal model systems	96
Toxicological inhalation studies in rats to substantiate grouping of zinc oxide nanoforms	94
Road tunnel-derived coarse, fine and ultrafine particulate matter: physical and chemical characterization and pro-inflammatory responses in human bronchial epithelial cells	92
An experimental study on lung deposition of inhaled 2 μm particles in relation to lung characteristics and deposition models	89
Placental-fetal distribution of carbon particles in a pregnant rabbit model after repeated exposure to diluted diesel engine exhaust	66
Toxicokinetic study following intratracheal instillation or oral gavage of two [7Be]-tagged carbon black samples	59
Impact on murine neurodevelopment of early-life exposure to airborne ultrafine carbon nanoparticles	57
Decidual derived exosomal miR-99a-5p targets Ppp2r5a to inhibit trophoblast invasion in response to CeO2NPs exposure	54
Titanium dioxide particles from the diet: involvement in the genesis of inflammatory bowel diseases and colorectal cancer	48
Polystyrene nanobeads exacerbate chronic colitis in mice involving in oxidative stress and hepatic lipid metabolism	46
An investigation of the internal morphology of asbestos ferruginous bodies: constraining their role in the onset of malignant mesothelioma	44
The pro-inflammatory effects of combined exposure to diesel exhaust particles and mineral particles in human bronchial epithelial cells	42
Short- and long-term pathologic responses to quartz are induced by nearly free silanols formed during crystal fracturing	40
Acute phase response following pulmonary exposure to soluble and insoluble metal oxide nanomaterials in mice	39
Prospects on the nano-plastic particles internalization and induction of cellular response in human keratinocytes	37
Surface functionalization and size modulate the formation of reactive oxygen species and genotoxic effects of cellulose nanofibrils	36
Attenuation of PM2.5-induced alveolar epithelial cells and lung injury through regulation of mitochondrial fission and fusion	36
ROS generation and p-38 activation contribute to montmorillonite-induced corneal toxicity in vitro and in vivo	35
Serum peptidome: diagnostic window into pathogenic processes following occupational exposure to carbon nanomaterials	34
Acute airway inflammation following controlled biodiesel exhaust exposure in healthy subjects	34
Correction: Reduction of pulmonary toxicity of metal oxide nanoparticles by phosphonate-based surface passivation	33

Establishing relationships between particle-induced in vitro and in vivo inflammation endpoints to better extrapolate between in vitro markers and in vivo fibrosis	32
Single inhalation exposure to polyamide micro and nanoplastic particles impairs vascular dilation without generating pulmonary inflammation in virgin female Sprague Dawley rats	31
Copper oxide nanoparticles trigger macrophage cell death with misfolding of Cu/Zn superoxide dismutase 1 (SOD1)	30
Silica-coated magnetic-nanoparticle-induced cytotoxicity is reduced in microglia by glutathione and citrate identified using integrated omics	29
A 90-day oral exposure to food-grade gold at relevant human doses impacts the gut microbiota and the local immune system in a sex-dependent manner in mice	29
Combined exposure to fine particulate matter and high glucose aggravates endothelial damage by increasing inflammation and mitophagy: the involvement of vitamin D	29
Food-grade titanium dioxide and zinc oxide nanoparticles induce toxicity and cardiac damage after oral exposure in rats	28
Effective density of inhaled environmental and engineered nanoparticles and its impact on the lung deposition and dosimetry	27
Dose–response relationship of pulmonary disorders by inhalation exposure to cross-linked water-soluble acrylic acid polymers in F344 rats	26
Airborne micro- and nanoplastics: emerging causes of respiratory diseases	26
Circulatory metabolites trigger ex vivo arterial endothelial cell dysfunction in population chronically exposed to diesel exhaust	25
Addressing the relevance of polystyrene nano- and microplastic particles used to support exposure, toxicity and risk assessment: implications and recommendations	25
Exposure to combustion derived particulate matter exacerbates influenza infection in neonatal mice by inhibiting IL22 production	25
Chronic effects of two rutile TiO2 nanomaterials in human intestinal and hepatic cell lines	25
Acute health effects of ambient air pollution including ultrafine particles in a semi-experimental setting in young, healthy individuals	23
Polystyrene nanoplastics exposure induces cognitive impairment in mice via induction of oxidative stress and ERK/MAPK-mediated neuronal cuproptosis	22
Silica encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte-complex expansion	22
Type 1 diabetes and diet-induced obesity predispose C57BL/6J mice to PM2.5-induced lung injury: a comparative study	22
The potential involvement of inhaled iron (Fe) in the neurotoxic effects of ultrafine particulate matter air pollution exposure on brain development in mice	22
The discovery of regional neurotoxicity-associated metabolic alterations induced by carbon quantum dots in brain of mice using a spatial metabolomics analysis	22
Ferroptosis contributing to cardiomyocyte injury induced by silica nanoparticles via miR-125b-2-3p/HO-1 signaling	22
Two-year intermittent exposure of a multiwalled carbon nanotube by intratracheal instillation induces lung tumors and pleural mesotheliomas in F344 rats	21
Epithelial MAPK signaling directs endothelial NRF2 signaling and IL-8 secretion in a tri-culture model of the alveolar-microvascular interface following diesel exhaust particulate (DEP) exposure	21
Hazard assessment of nanomaterials: how to meet the requirements for (next generation) risk assessment	21
Compositional and structural analysis of engineered stones and inorganic particles in silicotic nodules of exposed workers	20
Long-term exposure to polystyrene microplastics triggers premature testicular aging	20
Particulate matter from car exhaust alters function of human iPSC-derived microglia	19
Cellular response of keratinocytes to the entry and accumulation of nanoplastic particles	19
Polystyrene nanoplastics with different functional groups and charges have different impacts on type 2 diabetes	19
Prenatal PM2.5 exposure impairs spatial learning and memory in male mice offspring: from transcriptional regulation to neuronal morphogenesis	19
Murine in utero exposure to simulated complex urban air pollution disturbs offspring gut maturation and microbiota during intestinal suckling-to-weaning transition in a sex-dependent manner	19
Derivation of first-order dissolution rates to estimate particle clearance and burden in the human respiratory tract	19
Combustion-derived carbon nanoparticles cause delayed apoptosis in neutrophil-like HL-60 cells in vitro and in primed human neutrophilic granulocytes ex vivo	19