OOIR: Observatory of International Research

Papers

(The TQCC of Particle and Fibre Toxicology is 20. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature	275
The plastic brain: neurotoxicity of micro- and nanoplastics	271
Nanopolystyrene translocation and fetal deposition after acute lung exposure during late-stage pregnancy	186
Underestimated health risks: polystyrene micro- and nanoplastics jointly induce intestinal barrier dysfunction by ROS-mediated epithelial cell apoptosis	159
Adverse outcome pathways as a tool for the design of testing strategies to support the safety assessment of emerging advanced materials at the nanoscale	137
Impacts of foodborne inorganic nanoparticles on the gut microbiota-immune axis: potential consequences for host health	93
Impact of airborne particulate matter on skin: a systematic review from epidemiology to in vitro studies	90
Cardiovascular health impacts of wildfire smoke exposure	86
Silica nanoparticles induce lung inflammation in mice via ROS/PARP/TRPM2 signaling-mediated lysosome impairment and autophagy dysfunction	83
Chronic exposure to polystyrene microplastics induced male reproductive toxicity and decreased testosterone levels via the LH-mediated LHR/cAMP/PKA/StAR pathway	74
Induction of ferroptosis in response to graphene quantum dots through mitochondrial oxidative stress in microglia	73
The critical role of endothelial function in fine particulate matter-induced atherosclerosis	72
Recent insights on indirect mechanisms in developmental toxicity of nanomaterials	62
Translocation of (ultra)fine particles and nanoparticles across the placenta; a systematic review on the evidence of in vitro, ex vivo, and in vivo studies	61
Coronas of micro/nano plastics: a key determinant in their risk assessments	49
Basal Ti level in the human placenta and meconium and evidence of a materno-foetal transfer of food-grade TiO2 nanoparticles in an ex vivo placental perfusion model	49
Consequences of nano and microplastic exposure in rodent models: the known and unknown	48
Airborne particulate matter (PM2.5) triggers ocular hypertension and glaucoma through pyroptosis	46
Nanomaterial-mediated autophagy: coexisting hazard and health benefits in biomedicine	46
Ultrasmall iron oxide nanoparticles cause significant toxicity by specifically inducing acute oxidative stress to multiple organs	45
The mechanism of cell death induced by silver nanoparticles is distinct from silver cations	45
Sex-dependent effects of ambient PM2.5 pollution on insulin sensitivity and hepatic lipid metabolism in mice	43
Quartz crystal microbalances (QCM) are suitable for real-time dosimetry in nanotoxicological studies using VITROCELL®Cloud cell exposure systems	41
Pro-inflammatory effects of crystalline- and nano-sized non-crystalline silica particles in a 3D alveolar model	40
In vitro-in vivo correlations of pulmonary inflammogenicity and genotoxicity of MWCNT	39

Amorphous silica nanoparticles accelerated atherosclerotic lesion progression in ApoE−/− mice through endoplasmic reticulum stress-mediated CD36 up-regulation in macrophage	38
Influence of wood species on toxicity of log-wood stove combustion aerosols: a parallel animal and air-liquid interface cell exposure study on spruce and pine smoke	37
Size and surface modification of silica nanoparticles affect the severity of lung toxicity by modulating endosomal ROS generation in macrophages	37
Physicochemical characterization and genotoxicity of the broad class of carbon nanotubes and nanofibers used or produced in U.S. facilities	37
Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells	36
Particle characterization and toxicity in C57BL/6 mice following instillation of five different diesel exhaust particles designed to differ in physicochemical properties	35
Jejunal villus absorption and paracellular tight junction permeability are major routes for early intestinal uptake of food-grade TiO2 particles: an in vivo and ex vivo study in mice	35
Skin damage induced by zinc oxide nanoparticles combined with UVB is mediated by activating cell pyroptosis via the NLRP3 inflammasome–autophagy–exosomal pathway	34
Prospects on the nano-plastic particles internalization and induction of cellular response in human keratinocytes	34
Crystalline silica particles cause rapid NLRP3-dependent mitochondrial depolarization and DNA damage in airway epithelial cells	33
Polypropylene nanoplastic exposure leads to lung inflammation through p38-mediated NF-κB pathway due to mitochondrial damage	31
PM2.5 impairs macrophage functions to exacerbate pneumococcus-induced pulmonary pathogenesis	31
Amorphous SiO2 nanoparticles promote cardiac dysfunction via the opening of the mitochondrial permeability transition pore in rat heart and human cardiomyocytes	31
Comparative carcinogenicity study of a thick, straight-type and a thin, tangled-type multi-walled carbon nanotube administered by intra-tracheal instillation in the rat	30
Toxicity of particles emitted by fireworks	30
A comprehensive understanding of ambient particulate matter and its components on the adverse health effects based from epidemiological and laboratory evidence	29
Exposure to diesel exhaust particles results in altered lung microbial profiles, associated with increased reactive oxygen species/reactive nitrogen species and inflammation, in C57Bl/6 wildtype mice	29
Copper oxide nanoparticles trigger macrophage cell death with misfolding of Cu/Zn superoxide dismutase 1 (SOD1)	28
Zinc oxide nanoparticles effectively regulate autophagic cell death by activating autophagosome formation and interfering with their maturation	28
Repeated oral administration of low doses of silver in mice: tissue distribution and effects on central nervous system	26
Upregulation of ACE2 and TMPRSS2 by particulate matter and idiopathic pulmonary fibrosis: a potential role in severe COVID-19	25
Effects of metal nanoparticles on tight junction-associated proteins via HIF-1α/miR-29b/MMPs pathway in human epidermal keratinocytes	24
Low levels of fine particulate matter increase vascular damage and reduce pulmonary function in young healthy adults	24
Retained particle surface area dose drives inflammation in rat lungs following acute, subacute, and subchronic inhalation of nanomaterials	24
Titanium dioxide particles from the diet: involvement in the genesis of inflammatory bowel diseases and colorectal cancer	23
Diesel exhaust particle exposure reduces expression of the epithelial tight junction protein Tricellulin	23
Caloric restriction attenuates C57BL/6 J mouse lung injury and extra-pulmonary toxicity induced by real ambient particulate matter exposure	22
Nitrogen-doped graphene quantum dots induce ferroptosis through disrupting calcium homeostasis in microglia	21
Quantitative biokinetics over a 28 day period of freshly generated, pristine, 20 nm silver nanoparticle aerosols in healthy adult rats after a single 1½-hour inhalation exposure	21
The combined effect of food additive titanium dioxide and lipopolysaccharide on mouse intestinal barrier function after chronic exposure of titanium dioxide-contained feedstuffs	21
Controlled human exposures to wood smoke: a synthesis of the evidence	21
Oral toxicity of titanium dioxide P25 at repeated dose 28-day and 90-day in rats	21
Controlled human exposure to diesel exhaust: results illuminate health effects of traffic-related air pollution and inform future directions	21
Lung retention and particokinetics of silver and gold nanoparticles in rats following subacute inhalation co-exposure	20