OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Systems Biology is 34. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
ENDORSE: a prognostic model for endocrine therapy in estrogen‐receptor‐positive breast cancers	366
Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data	199
Gemcitabine and ATR inhibitors synergize to kill PDAC cells by blocking DNA damage response	148
A genome‐scale TF–DNA interaction network of transcriptional regulation ofArabidopsisprimary and specialized metabolism	115
Stress‐sensitive dynamics of miRNAs and Elba1 in Drosophila embryogenesis	107
Quantifying the phenotypic information in mRNA abundance	106
Engineering a genome‐reduced bacterium to eliminate Staphylococcus aureus biofilms in vivo	98
A human kinase yeast array for the identification of kinases modulating phosphorylation‐dependent protein–protein interactions	93
Cell‐to‐cell and type‐to‐type heterogeneity of signaling networks: insights from the crowd	91
Metabolic balance in colorectal cancer is maintained by optimal Wnt signaling levels	82
High diversity in Delta variant across countries revealed by genome‐wide analysis of SARS‐CoV‐2 beyond the Spike protein	79
Differentiation‐related epigenomic changes define clinically distinct keratinocyte cancer subclasses	76
TNF stimulation primarily modulates transcriptional burst size of NF‐κB‐regulated genes	71
Vesalius: high‐resolution in silico anatomization of spatial transcriptomic data using image analysis	64
Quantitative contributions of TNF receptor superfamily members to CD8 ⁺ T‐cell responses	62
Systematic identification of 20S proteasome substrates	60
Dynamic human liver proteome atlas reveals functional insights into disease pathways	60
The population context is a driver of the heterogeneous response of epithelial cells to interferons	59
Uncovering the dynamics and consequences of RNA isoform changes during neuronal differentiation	56
µPhos: a scalable and sensitive platform for high-dimensional phosphoproteomics	51
A split intein and split luciferase-coupled system for detecting protein-protein interactions	51
Development and validation of AI/ML derived splice-switching oligonucleotides	50
A new way of looking at transcription factor assays	50
An integrative epigenome-based strategy for unbiased functional profiling of clinical kinase inhibitors	49
A ubiquitous GC content signature underlies multimodal mRNA regulation by DDX3X	47

Dengue virus preferentially uses human and mosquito non-optimal codons	46
Linking patient-specific basal MET phosphorylation levels to liver health	42
Hotspot propensity across mutational processes	40
Exploring the microbial savanna: predator-prey interactions in the soil	38
Genome‐scale metabolic modeling reveals key features of a minimal gene set	37
Proteome‐scale mapping of binding sites in the unstructured regions of the human proteome	35
Coordination of MAPK and p53 dynamics in the cellular responses to DNA damage and oxidative stress	35
Subcellular mRNA kinetic modeling reveals nuclear retention as rate-limiting	34
SLAM‐Drop‐seq reveals mRNA kinetic rates throughout the cell cycle	34