OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Systems Biology is 29. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Stress‐sensitive dynamics of miRNAs and Elba1 in Drosophila embryogenesis	428
Dynamic human liver proteome atlas reveals functional insights into disease pathways	208
Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data	168
Exogenous prion-like proteins and their potential to trigger cognitive dysfunction	115
Systematic identification of 20S proteasome substrates	79
Development and validation of AI/ML derived splice-switching oligonucleotides	76
A split intein and split luciferase-coupled system for detecting protein-protein interactions	73
State of the interactomes: an evaluation of molecular networks for generating biological insights	65
Methylation reprogramming associated with aggressive prostate cancer and ancestral disparities	65
Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation	57
Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs	56
Dimensionality reduction methods for extracting functional networks from large‐scaleCRISPRscreens	55
Suboptimal resource allocation in changing environments constrains response and growth in bacteria	53
Enhancing nutritional niche and host defenses by modifying the gut microbiome	52
Host inflammatory dynamics reveal placental immune modulation by Group B Streptococcus during pregnancy	46
Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations	45
A transient mutational burst occurs during yeast colony development	43
A proximity proteomics pipeline with improved reproducibility and throughput	43
Epigenomic landscape of single vascular cells reflects developmental origin and disease risk loci	40
Predicting cellular responses to complex perturbations in high‐throughput screens	40
Author Correction: From coarse to fine: the absolute Escherichia coli proteome under diverse growth conditions	37
What we can learn from deep space communication for reproducible bioimaging and data analysis	36
Metabolic mutations reduce antibiotic susceptibility of E. coli by pathway-specific bottlenecks	35
Comprehensive quantitative modeling of translation efficiency in a genome‐reduced bacterium	33
Characterizing chemical signaling between engineered “microbial sentinels” in porous microplates	32

The genotype‐phenotype landscape of an allosteric protein	31
Systematic identification of structure-specific protein–protein interactions	31
Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community	30
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT)	30
Author Correction: Predictive evolution of metabolic phenotypes using model-designed environments	29
Turnover and replication analysis by isotope labeling (TRAIL) reveals the influence of tissue context on protein and organelle lifetimes	29
Pan‐Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival	29
Predicting natural variation in the yeast phenotypic landscape with machine learning	29
Deep learning for protein structure prediction and design—progress and applications	29