OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Systems Biology is 33. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
A split intein and split luciferase-coupled system for detecting protein-protein interactions	401
Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data	219
Development and validation of AI/ML derived splice-switching oligonucleotides	163
State of the interactomes: an evaluation of molecular networks for generating biological insights	137
Exogenous prion-like proteins and their potential to trigger cognitive dysfunction	108
Systematic identification of 20S proteasome substrates	107
Dynamic human liver proteome atlas reveals functional insights into disease pathways	93
Cell‐to‐cell and type‐to‐type heterogeneity of signaling networks: insights from the crowd	93
Stress‐sensitive dynamics of miRNAs and Elba1 in Drosophila embryogenesis	88
SARS‐CoV‐2–host proteome interactions for antiviral drug discovery	71
Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation	70
Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs	67
A transient mutational burst occurs during yeast colony development	66
Host inflammatory dynamics reveal placental immune modulation by Group B Streptococcus during pregnancy	63
Evaluating the Arrhenius equation for developmental processes	61
Suboptimal resource allocation in changing environments constrains response and growth in bacteria	56
Dimensionality reduction methods for extracting functional networks from large‐scaleCRISPRscreens	52
Enhancing nutritional niche and host defenses by modifying the gut microbiome	49
A proximity proteomics pipeline with improved reproducibility and throughput	48
High‐efficiency delivery of CRISPR‐Cas9 by engineered probiotics enables precise microbiome editing	48
Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations	43
Predicting cellular responses to complex perturbations in high‐throughput screens	43
Adaptive laboratory evolution of microbial co‐cultures for improved metabolite secretion	42
Systematic identification of structure-specific protein–protein interactions	41
Author Correction: From coarse to fine: the absolute Escherichia coli proteome under diverse growth conditions	40

What we can learn from deep space communication for reproducible bioimaging and data analysis	40
The genotype‐phenotype landscape of an allosteric protein	39
Metabolic mutations reduce antibiotic susceptibility of E. coli by pathway-specific bottlenecks	39
Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community	35
Deep learning for protein structure prediction and design—progress and applications	35
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT)	34
Tensor‐structured decomposition improves systems serology analysis	33
Machine learning identifies molecular regulators and therapeutics for targeting SARS‐CoV2‐induced cytokine release	33