OOIR: Observatory of International Research

Papers

(The H4-Index of Molecular Systems Biology is 30. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Systematic identification of 20S proteasome substrates	444
Development and validation of AI/ML derived splice-switching oligonucleotides	224
Stress‐sensitive dynamics of miRNAs and Elba1 in Drosophila embryogenesis	188
Methylation reprogramming associated with aggressive prostate cancer and ancestral disparities	124
A split intein and split luciferase-coupled system for detecting protein-protein interactions	84
State of the interactomes: an evaluation of molecular networks for generating biological insights	79
Exogenous prion-like proteins and their potential to trigger cognitive dysfunction	78
Dynamic human liver proteome atlas reveals functional insights into disease pathways	69
Leveraging prior knowledge to infer gene regulatory networks from single-cell RNA-sequencing data	62
Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation	61
Molecular Systems Biology at 20: reflecting on the past, envisioning the future	58
Author Correction: Systematic protein-protein interaction mapping for clinically relevant human GPCRs	56
A transient mutational burst occurs during yeast colony development	55
Host inflammatory dynamics reveal placental immune modulation by Group B Streptococcus during pregnancy	50
Enhancing nutritional niche and host defenses by modifying the gut microbiome	50
A proximity proteomics pipeline with improved reproducibility and throughput	46
Dimensionality reduction methods for extracting functional networks from large‐scale CRISPR screens	45
Author Correction: Spatial proteomics of ovarian cancer precursors delineates early disease changes and drug targets	44
Predicting cellular responses to complex perturbations in high‐throughput screens	43
Time‐series transcriptomics and proteomics reveal alternative modes to decode p53 oscillations	42
Author Correction: From coarse to fine: the absolute Escherichia coli proteome under diverse growth conditions	39
Characterizing chemical signaling between engineered “microbial sentinels” in porous microplates	38
Epigenomic landscape of single vascular cells reflects developmental origin and disease risk loci	38
What we can learn from deep space communication for reproducible bioimaging and data analysis	36
Comprehensive quantitative modeling of translation efficiency in a genome‐reduced bacterium	34

Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community	33
Metabolic mutations reduce antibiotic susceptibility of E. coli by pathway-specific bottlenecks	33
Systematic identification of structure-specific protein–protein interactions	33
Deep learning for protein structure prediction and design—progress and applications	31
Detection of PatIent-Level distances from single cell genomics and pathomics data with Optimal Transport (PILOT)	31
Author Correction: Predictive evolution of metabolic phenotypes using model-designed environments	30
Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis	30
Pan‐Cancer landscape of protein activities identifies drivers of signalling dysregulation and patient survival	30