OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Clinical Immunology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Pioglitazone as a potential modulator in autoimmune diseases: a review on its effects in systemic lupus erythematosus, psoriasis, inflammatory bowel disease, and multiple sclerosis	115
How could our genetics impact COVID-19 vaccine response?	89
Will SARS-CoV-2 impact the incidence and nature of other respiratory infections?	83
Pan-cancer analysis of the prognostic significance of ACKR2 expression and the related genetic/epigenetic dysregulations	69
The multidisciplinary approach to diagnosing inborn errors of immunity: a comprehensive review of discipline-based manifestations	62
Full consideration of the pollen exposure effect in clinical trial design for pollen-induced allergic rhinitis	59
Bradford Hill and breast implant illness: no evidence for causal association with breast implants	59
A critical review of dupilumab for adult patients with prurigo nodularis	54
Bimekizumab for the treatment of psoriatic arthritis	51
Aleukemic variant of T-cell large granular lymphocyte leukemia in patients with rheumatoid arthritis - diagnostically challenging subtype	37
Immunobiology and treatment of cutaneous T-cell lymphoma	35
A prospective single-arm study on the efficacy and safety of short-course oral corticosteroids followed by topical corticosteroids in patients with severe chronic rhinosinusitis with nasal polyps	33
The therapeutic effect of mRNA vaccines in glioma: a comprehensive review	33
IRF1 expression might be a biomarker of CD8+ T cell infiltration in cutaneous melanoma	32
The effect of intense pulsed light combined with topical 0.05% Cyclosporin A eyedrops in the treatment of Sjögren’s syndrome related dry eye	32
Ruxolitinib as the first post-steroid treatment for acute and chronic graft-versus-host disease	30
Pathogen-specific cell-mediated immunity to guide the management of cytomegalovirus in solid organ transplantation: state of the art clinical review	29
Food immunotherapy: current status and future needs	28
How to and should we target EBV in MS?	27
Biomarkers guiding biological therapeutic strategies in chronic rhinosinusitis with nasal polyps: an emerging challenge	27
More than a random association between chronic obstructive pulmonary disease and psoriatic arthritis: shared pathogenic features and implications for treatment	27
Differential risk of autoimmune disorders in non-traumatic osteonecrosis: clue to pathogenesis	26
Dupilumab in chronic rhinosinusitis with nasal polyposis: current status, challenges, and future perspectives	26
Re-evaluation of nailfold capillaroscopy in discriminating primary from secondary Raynaud’s phenomenon and in predicting systemic sclerosis: a randomised observational prospective cohort study	22
Recent insights into the pathogenesis of autoimmune hypophysitis	22

Emergence of an adaptive immune paradigm to explain celiac disease: a perspective on new evidence and implications for future interventions and diagnosis	22
Evaluating the use of JAK inhibitors in inflammatory connective tissue diseases in pediatric patients: an update	21
Current treatment options and long-term outcomes in patients with eosinophilic esophagitis	21
Advances in therapeutic targeting of immune checkpoints receptors within the CD96-TIGIT axis: clinical implications and future perspectives	20
Rare forms of inflammatory myopathies – part I, generalized forms	20
Pharmacokinetics and tolerability of prefilled syringe and auto-injector presentations of MSB11456: results of a randomized, single-dose study in healthy adults	19
Impact of anti-PD1 immunotherapy and circulating tumor cells on progression-free survival in surgical pancreatic adenocarcinoma: a retrospective cohort study	19
An exercise immune fitness test to unravel mechanisms of Post-Acute Sequelae of COVID-19	19
Durability and long-term outcomes of biologic therapies in psoriasis	18
How do nuclear factor kappa B (NF-κB)1 and NF-κB2 defects lead to the incidence of clinical and immunological manifestations of inborn errors of immunity?	18
Gut immune homeostasis: the immunomodulatory role of Bacillus clausii, from basic to clinical evidence	18
Transcriptional regulation of B cell class-switch recombination: the role in development of noninfectious complications	18
Neurological adverse effects of chimeric antigen receptor T-cell therapy	17
Direct economic burden 1 year postoperation in Chinese adult patients with chronic rhinosinusitis with nasal polyps	17
The functional role and the clinical application of periostin in chronic rhinosinusitis	16
Classification and management strategies for paediatric chronic nonbacterial osteomyelitis and chronic recurrent multifocal osteomyelitis	16
Pathophysiology and management of Staphylococcus aureus in nasal polyp disease	16
Immune mechanisms, the role of complement, and related therapies in autoimmune neuropathies	15
Sicca syndrome/Sjögren’s disease associated with cancer immunotherapy: a narrative review on clinical presentation, biomarkers, and management	15
Novel insights into the pathogenesis of virus-induced ARDS: review on the central role of the epithelial-endothelial barrier	15
Advancements in immunotherapy for advanced esophageal squamous cell carcinoma: a comprehensive review of current strategies and future directions	15
T-lymphocyte depleted transplants for inborn errors of immunity	15
CSE1L as a prognostic biomarker associated with pan cancer immune infiltration and drug sensitivity	15
Inflammatory myopathy in adults, health-related quality of life, and wellbeing: a round trip between immune disease and wellness	14
Transcriptomic observations of intra and extracellular immunotherapy targets for pediatric brain tumors	14
The role of interleukins in pathogenesis and prognosis of atrial fibrillation	14
An updated evaluation of avatrombopag for the treatment of chronic immune thrombocytopenia	14
Perspectives for immunotherapy in noninfectious immune mediated uveitis	13
Recent updates in the diagnosis and management of cryoglobulinemic vasculitis	13
Patient-centered approaches for patients with systemic autoimmune rheumatic diseases: development and evolution	13
Safety of JAK inhibitors: focus on cardiovascular and thromboembolic events	13
Diagnostic accuracy of QuantiFERON-TB gold plus with chemiluminescence immunoassay: a systematic review and meta-analysis	13
Challenges in uncontrolled asthma in pediatrics: important considerations for the clinician	13
Recent insights into comorbidities in atopic dermatitis	13
Advances in tumor immunotherapy targeting macrophages	13
Peanut allergy: risk factors, immune mechanisms, and best practices for oral immunotherapy success	12
Insights into the immunological links between dietary habits and asthma	12
Toward a personalized therapy of still’s disease based on immunologic endotypes: a narrative review	12
Interferon beta-1a sc at 25 years: a mainstay in the treatment of multiple sclerosis over the period of one generation	12
Harnessing the power of AI-based models to accelerate drug discovery against immune diseases	11
Glucocorticoid in systemic lupus erythematosus: the art beyond science	11
Updates in toxicities associated with immune checkpoint inhibitors	11
Monoclonal antibodies in diabetic retinopathy	11
Temporal trends in anaphylaxis ED visits over the last decade and the effect of COVID-19 pandemic on these trends	11
Current approaches for diagnosis of subclinical pulmonary tuberculosis, clinical implications and future perspectives: a scoping review	11
The interaction between innate immunity and oral microbiota in oral diseases	11
Subcutaneous immunoglobulin 16.5% for the treatment of pediatric patients with primary antibody immunodeficiency	11
At the cutting-edge: what’s the latest in imaging to diagnose Sjögren’s disease?	11
Antiphospholipid antibodies and the risk of adverse pregnancy outcomes in patients with systemic lupus erythematosus: a systematic review and meta-analysis	10
Immunology and targeted therapy in Castleman disease	10

How does sleep influence asthma through immunity?	10
The role of serological biomarkers in the diagnosis and management of autoimmune pancreatitis	10
Basophil activation test in the food allergy clinic: its current use and future applications	10
Guidance for stem cell therapy for juvenile systemic sclerosis patients	10
Colorectal medullary carcinoma: a pathological subtype with intense immune response and potential to benefit from immune checkpoint inhibitors	10
Letter to the editor regarding ‘perspective: diagnostic laboratories should urgently develop T cell assays for SARS-CoV-2 infection’	10
B cell depletion and inhibition in systemic lupus erythematosus	10
What place will tezepelumab hold in the treatment paradigm in chronic rhinosinusitis?	10
Comparing available JAK inhibitors for treating patients with psoriasis	10
Update on virus-induced asthma exacerbations	10
Pediatric IgG4-related disease: a descriptive review	10
Abdeg technology for the treatment of myasthenia gravis: efgartigimod drug experience	10
Hemophagocytic lymphohistiocytosis post chimeric antigen receptor T cell therapies	10
Skin infections during dupilumab monotherapy in moderate-to-severe atopic dermatitis – a meta-analysis of randomized clinical trials	10
Definition of severity and treatment response in chronic rhinosinusitis with nasal polyps: a Delphi study among French experts	10
Budesonide delayed-release capsules to reduce proteinuria in adults with primary immunoglobulin A nephropathy	10
Genetic polymorphisms impacting clinical pharmacology of drugs used to treat inflammatory bowel disease: a precursor to multi-omics approach to precision medicine	10
The role of immune reconstitution in relapse after allogeneic hematopoietic stem cell transplantation	10
Gut-brain communication in COVID-19: molecular mechanisms, mediators, biomarkers, and therapeutics	10
Induction of aquaporins by plasma of patients with systemic lupus erythematosus	10
Individual differences in response to dust-mite-allergen specific immunotherapy in allergic rhinitis: a meta-analysis of randomized controlled trials	9
An update on VEXAS syndrome	9
How suitable is intravenous tocilizumab for the treatment of Graves’ ophthalmopathy?	9
The clinical role of anakinra in the armamentarium against familial Mediterranean fever	9
Interleukin 6 in diabetes, chronic kidney disease, and cardiovascular disease: mechanisms and therapeutic perspectives	9
Risk of infections in psoriasis: assessment and challenges in daily management	9
Model-based computational precision medicine to develop combination therapies for autoimmune diseases	9
An evaluation of anifrolumab for use in adults with systemic lupus erythematosus	9
Systemic therapy in juvenile localized scleroderma	9
Epstein–Barr virus-driven lymphoproliferation in inborn errors of immunity: a diagnostic and therapeutic challenge	9
The (apparent) antibody paradox in COVID-19	9
A review of disease burden and clinical management for generalized pustular psoriasis in China	9
Tofacitinib for the treatment of active ankylosing spondylitis in adults	9
Treatment controversies in spondyloarthritis and psoriatic arthritis: focus on biologics and targeted therapies	9
Role of tight junction proteins in shaping the immune milieu of malignancies	9
Characterizing the immune tumor microenvironment in ALK fusion-positive lung cancer: state-of-the-art and therapeutical implications	9
Vascular endothelial dysfunction in pediatric rheumatic diseases: a systematic review and meta-analysis	8
Evaluating topical JAK inhibitors as a treatment option for atopic dermatitis	8
Biomarkers for systemic lupus erythematosus – a focus on organ damage	8
Late effects following hematopoietic cell transplantation for severe combined immunodeficiency: critical factors and therapeutic options	8
The suitability of treating atopic dermatitis with Janus kinase inhibitors	8
Considerations for managing elderly patients with atopic dermatitis	8
Treatment strategies for ANCA-associated vasculitides: from standard protocols to future horizons	8
Early diagnosis of systemic sclerosis, where do we stand today?	8
Clinical and immunologic implication of neo-osteogenesis in chronic rhinosinusitis	8
Management and treatment optimization of patients with mild to moderate ulcerative colitis	8
The role of PCSK9 in inflammation, immunity, and autoimmune diseases	8
The emerging role of IL-23 in asthma and its clinical implications	8
Response to letter to the editor: Bradford Hill and breast implant illness: evidence for a causal association with breast implants	8
AQP9 weakens the cytotoxicity of CD8 ⁺ T cells in colon adenocarcinoma by boosting M2 polarization of macrophages under hypoxia conditions	8
Efgartigimod for generalized myasthenia gravis with or without anti-acetylcholine receptor antibodies: a worldwide and Japanese perspective	8