OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Clinical Immunology is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Full consideration of the pollen exposure effect in clinical trial design for pollen-induced allergic rhinitis	114
Will SARS-CoV-2 impact the incidence and nature of other respiratory infections?	84
Pepsin, trypsin, and MUC5B are independent risk factors for hearing impairment in patients with laryngopharyngeal reflux-related chronic secretory otitis media	67
The therapeutic effect of mRNA vaccines in glioma: a comprehensive review	64
Aleukemic variant of T-cell large granular lymphocyte leukemia in patients with rheumatoid arthritis - diagnostically challenging subtype	58
Immunobiology and treatment of cutaneous T-cell lymphoma	55
Bimekizumab for the treatment of psoriatic arthritis	55
How could our genetics impact COVID-19 vaccine response?	42
Pan-cancer analysis of the prognostic significance of ACKR2 expression and the related genetic/epigenetic dysregulations	40
Pioglitazone as a potential modulator in autoimmune diseases: a review on its effects in systemic lupus erythematosus, psoriasis, inflammatory bowel disease, and multiple sclerosis	39
CAR-T cell immunotherapy of malignant melanoma	33
A prospective single-arm study on the efficacy and safety of short-course oral corticosteroids followed by topical corticosteroids in patients with severe chronic rhinosinusitis with nasal polyps	32
The multidisciplinary approach to diagnosing inborn errors of immunity: a comprehensive review of discipline-based manifestations	31
A critical review of dupilumab for adult patients with prurigo nodularis	31
Bradford Hill and breast implant illness: no evidence for causal association with breast implants	30
Dupilumab in chronic rhinosinusitis with nasal polyposis: current status, challenges, and future perspectives	30
Ruxolitinib as the first post-steroid treatment for acute and chronic graft-versus-host disease	29
The effect of intense pulsed light combined with topical 0.05% Cyclosporin A eyedrops in the treatment of Sjögren’s syndrome related dry eye	29
IRF1 expression might be a biomarker of CD8+ T cell infiltration in cutaneous melanoma	28
Re-evaluation of nailfold capillaroscopy in discriminating primary from secondary Raynaud’s phenomenon and in predicting systemic sclerosis: a randomised observational prospective cohort study	27
Food immunotherapy: current status and future needs	27
More than a random association between chronic obstructive pulmonary disease and psoriatic arthritis: shared pathogenic features and implications for treatment	27
Pathogen-specific cell-mediated immunity to guide the management of cytomegalovirus in solid organ transplantation: state of the art clinical review	27
Biomarkers guiding biological therapeutic strategies in chronic rhinosinusitis with nasal polyps: an emerging challenge	27
Differential risk of autoimmune disorders in non-traumatic osteonecrosis: clue to pathogenesis	26

Drug development in systemic sclerosis: novel therapeutics to watch	26
How to and should we target EBV in MS?	23
Neurological adverse effects of chimeric antigen receptor T-cell therapy	22
Inflammatory bowel disease and primary sclerosing cholangitis: immunological links and clinical outlook	22
Impact of anti-PD1 immunotherapy and circulating tumor cells on progression-free survival in surgical pancreatic adenocarcinoma: a retrospective cohort study	22
Current treatment options and long-term outcomes in patients with eosinophilic esophagitis	21
Transcriptional regulation of B cell class-switch recombination: the role in development of noninfectious complications	21
Rare forms of inflammatory myopathies – part I, generalized forms	21
Durability and long-term outcomes of biologic therapies in psoriasis	20
Gut immune homeostasis: the immunomodulatory role of Bacillus clausii, from basic to clinical evidence	20
Pharmacokinetics and tolerability of prefilled syringe and auto-injector presentations of MSB11456: results of a randomized, single-dose study in healthy adults	20
Advances in therapeutic targeting of immune checkpoints receptors within the CD96-TIGIT axis: clinical implications and future perspectives	19
Classification and management strategies for paediatric chronic nonbacterial osteomyelitis and chronic recurrent multifocal osteomyelitis	19
Direct economic burden 1 year postoperation in Chinese adult patients with chronic rhinosinusitis with nasal polyps	19
An exercise immune fitness test to unravel mechanisms of Post-Acute Sequelae of COVID-19	19
Next-generation sequencing reveals genetic heterogeneity in MEFV -negative or heterozygous familial Mediterranean fever: a retrospective study	18
T-lymphocyte depleted transplants for inborn errors of immunity	17
Inflammatory myopathy in adults, health-related quality of life, and wellbeing: a round trip between immune disease and wellness	17
Personalization of therapy for patients with eosinophilic esophagitis	17
Transcriptomic observations of intra and extracellular immunotherapy targets for pediatric brain tumors	17
How do nuclear factor kappa B (NF-κB)1 and NF-κB2 defects lead to the incidence of clinical and immunological manifestations of inborn errors of immunity?	17
Eradicating measurable residual disease via immunotherapy to cure acute lymphoblastic leukemia: current status and future directions	16
The functional role and the clinical application of periostin in chronic rhinosinusitis	16
Pathophysiology and management of Staphylococcus aureus in nasal polyp disease	16
An updated evaluation of avatrombopag for the treatment of chronic immune thrombocytopenia	16
Recent insights into comorbidities in atopic dermatitis	15
Challenges in uncontrolled asthma in pediatrics: important considerations for the clinician	15
CSE1L as a prognostic biomarker associated with pan cancer immune infiltration and drug sensitivity	15
The role of interleukins in pathogenesis and prognosis of atrial fibrillation	15
Advancements in immunotherapy for advanced esophageal squamous cell carcinoma: a comprehensive review of current strategies and future directions	15
The intratumor microbiome and cancer immunity: from pathogenesis to therapeutic opportunities through artificial intelligence	15
Chronic obstructive pulmonary disease, biological agents and small molecules: where do we stand?	15
IL-17A in psoriatic arthritis: mechanistic insights, clinical implications, and advances in therapeutic strategies	15
Sicca syndrome/Sjögren’s disease associated with cancer immunotherapy: a narrative review on clinical presentation, biomarkers, and management	15
Old and new autoantibodies in systemic lupus erythematosus	15
Insights into the immunological links between dietary habits and asthma	14
Toward a personalized therapy of still’s disease based on immunologic endotypes: a narrative review	14
Interferon beta-1a sc at 25 years: a mainstay in the treatment of multiple sclerosis over the period of one generation	14
Recent updates in the diagnosis and management of cryoglobulinemic vasculitis	14
Temporal trends in anaphylaxis ED visits over the last decade and the effect of COVID-19 pandemic on these trends	14
Peanut allergy: risk factors, immune mechanisms, and best practices for oral immunotherapy success	14
Translational approaches to childhood inflammatory brain diseases: a review	13
Updates in toxicities associated with immune checkpoint inhibitors	13
Induction of aquaporins by plasma of patients with systemic lupus erythematosus	13
At the cutting-edge: what’s the latest in imaging to diagnose Sjögren’s disease?	13
Advances in tumor immunotherapy targeting macrophages	13
Glucocorticoid in systemic lupus erythematosus: the art beyond science	13
What place will tezepelumab hold in the treatment paradigm in chronic rhinosinusitis?	13
Subcutaneous immunoglobulin 16.5% for the treatment of pediatric patients with primary antibody immunodeficiency	13
Diagnostic accuracy of QuantiFERON-TB gold plus with chemiluminescence immunoassay: a systematic review and meta-analysis	13

New advances on the interaction between internal and external factors in the tumor microenvironment of solid tumors	13
The role of serological biomarkers in the diagnosis and management of autoimmune pancreatitis	13
Pediatric IgG4-related disease: a descriptive review	12
State of art and future challenges to early intervention, and management in patients with psoriasis at increased risk of transition to psoriatic arthritis: a review	12
Immunology and targeted therapy in Castleman disease	12
Skin infections during dupilumab monotherapy in moderate-to-severe atopic dermatitis – a meta-analysis of randomized clinical trials	12
The role of interleukin-15 in the spectrum of inflammatory diseases	12
Current approaches for diagnosis of subclinical pulmonary tuberculosis, clinical implications and future perspectives: a scoping review	12
Definition of severity and treatment response in chronic rhinosinusitis with nasal polyps: a Delphi study among French experts	12
How does sleep influence asthma through immunity?	12
Genetic polymorphisms impacting clinical pharmacology of drugs used to treat inflammatory bowel disease: a precursor to multi-omics approach to precision medicine	11
Hemophagocytic lymphohistiocytosis post chimeric antigen receptor T cell therapies	11
Budesonide delayed-release capsules to reduce proteinuria in adults with primary immunoglobulin A nephropathy	11
Harnessing the power of AI-based models to accelerate drug discovery against immune diseases	11
The interaction between innate immunity and oral microbiota in oral diseases	11
Basophil activation test in the food allergy clinic: its current use and future applications	11
Antiphospholipid antibodies and the risk of adverse pregnancy outcomes in patients with systemic lupus erythematosus: a systematic review and meta-analysis	11
Guidance for stem cell therapy for juvenile systemic sclerosis patients	11
Gut-brain communication in COVID-19: molecular mechanisms, mediators, biomarkers, and therapeutics	11
Vascular endothelial dysfunction in pediatric rheumatic diseases: a systematic review and meta-analysis	10
Systemic therapy in juvenile localized scleroderma	10
B cell depletion and inhibition in systemic lupus erythematosus	10
A review of disease burden and clinical management for generalized pustular psoriasis in China	10
Phosphoinositide-3-kinase δ as an immune check-pathway in cancer Immunology. Therapeutic prospects	10
Update on virus-induced asthma exacerbations	10
An update on VEXAS syndrome	10
Characterizing the immune tumor microenvironment in ALK fusion-positive lung cancer: state-of-the-art and therapeutical implications	10
Role of tight junction proteins in shaping the immune milieu of malignancies	10
Dysautonomia in systemic lupus erythematosus: when to suspect and how to investigate	10
Sequential immunotherapy for alopecia areata: phase-driven immune rebalancing	10
Potential approaches in repairing the damaged epithelial barrier in eosinophilic esophagitis	10
Abdeg technology for the treatment of myasthenia gravis: efgartigimod drug experience	10
An evaluation of anifrolumab for use in adults with systemic lupus erythematosus	10
Treatment controversies in spondyloarthritis and psoriatic arthritis: focus on biologics and targeted therapies	10
Colorectal medullary carcinoma: a pathological subtype with intense immune response and potential to benefit from immune checkpoint inhibitors	10
The role of immune reconstitution in relapse after allogeneic hematopoietic stem cell transplantation	10
Individual differences in response to dust-mite-allergen specific immunotherapy in allergic rhinitis: a meta-analysis of randomized controlled trials	10
Transglutaminase 2 in chronic inflammation and fibrosis – a potential novel therapy for stricturing Crohn’s disease	10
The clinical role of anakinra in the armamentarium against familial Mediterranean fever	9
Treatment strategies for ANCA-associated vasculitides: from standard protocols to future horizons	9
Management and treatment optimization of patients with mild to moderate ulcerative colitis	9
Efgartigimod for generalized myasthenia gravis with or without anti-acetylcholine receptor antibodies: a worldwide and Japanese perspective	9
Mechanisms and therapeutic potential of epithelial-immune crosstalk in airway inflammation	9
Biomarkers for systemic lupus erythematosus – a focus on organ damage	9
Epstein–Barr virus-driven lymphoproliferation in inborn errors of immunity: a diagnostic and therapeutic challenge	9
Interleukin-33/ST2 axis in Kawasaki disease: biology, vascular pathology, and future therapeutic strategies	9
The emerging role of IL-23 in asthma and its clinical implications	9
The relationship between interleukin 17A rs2275913 gene polymorphism and circulating IL17A levels and disease activity and severity in Egyptian rheumatoid arthritis patients	9
Advancing kidney protection in type 1 diabetes: insights from emerging therapies in type 2 diabetes and chronic kidney disease	9
Considerations for managing elderly patients with atopic dermatitis	9
Asthma and neurodevelopmental and mental health disorder (NMD) multimorbidity in rural children	9
Clinical and immunologic implication of neo-osteogenesis in chronic rhinosinusitis	9