OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Clinical Immunology is 8. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Full consideration of the pollen exposure effect in clinical trial design for pollen-induced allergic rhinitis	100
Will SARS-CoV-2 impact the incidence and nature of other respiratory infections?	98
Pepsin, trypsin, and MUC5B are independent risk factors for hearing impairment in patients with laryngopharyngeal reflux-related chronic secretory otitis media	81
A critical review of dupilumab for adult patients with prurigo nodularis	76
A prospective single-arm study on the efficacy and safety of short-course oral corticosteroids followed by topical corticosteroids in patients with severe chronic rhinosinusitis with nasal polyps	60
Pan-cancer analysis of the prognostic significance of ACKR2 expression and the related genetic/epigenetic dysregulations	58
The multidisciplinary approach to diagnosing inborn errors of immunity: a comprehensive review of discipline-based manifestations	50
Aleukemic variant of T-cell large granular lymphocyte leukemia in patients with rheumatoid arthritis - diagnostically challenging subtype	49
Immunobiology and treatment of cutaneous T-cell lymphoma	46
Bimekizumab for the treatment of psoriatic arthritis	38
The therapeutic effect of mRNA vaccines in glioma: a comprehensive review	37
Bradford Hill and breast implant illness: no evidence for causal association with breast implants	36
How could our genetics impact COVID-19 vaccine response?	36
Pioglitazone as a potential modulator in autoimmune diseases: a review on its effects in systemic lupus erythematosus, psoriasis, inflammatory bowel disease, and multiple sclerosis	31
Food immunotherapy: current status and future needs	29
Biomarkers guiding biological therapeutic strategies in chronic rhinosinusitis with nasal polyps: an emerging challenge	29
The effect of intense pulsed light combined with topical 0.05% Cyclosporin A eyedrops in the treatment of Sjögren’s syndrome related dry eye	28
Pathogen-specific cell-mediated immunity to guide the management of cytomegalovirus in solid organ transplantation: state of the art clinical review	28
Ruxolitinib as the first post-steroid treatment for acute and chronic graft-versus-host disease	26
More than a random association between chronic obstructive pulmonary disease and psoriatic arthritis: shared pathogenic features and implications for treatment	25
Re-evaluation of nailfold capillaroscopy in discriminating primary from secondary Raynaud’s phenomenon and in predicting systemic sclerosis: a randomised observational prospective cohort study	25
Differential risk of autoimmune disorders in non-traumatic osteonecrosis: clue to pathogenesis	25
Dupilumab in chronic rhinosinusitis with nasal polyposis: current status, challenges, and future perspectives	24
How to and should we target EBV in MS?	24
Advances in therapeutic targeting of immune checkpoints receptors within the CD96-TIGIT axis: clinical implications and future perspectives	23

An exercise immune fitness test to unravel mechanisms of Post-Acute Sequelae of COVID-19	23
IRF1 expression might be a biomarker of CD8+ T cell infiltration in cutaneous melanoma	23
Evaluating the use of JAK inhibitors in inflammatory connective tissue diseases in pediatric patients: an update	21
How do nuclear factor kappa B (NF-κB)1 and NF-κB2 defects lead to the incidence of clinical and immunological manifestations of inborn errors of immunity?	21
Impact of anti-PD1 immunotherapy and circulating tumor cells on progression-free survival in surgical pancreatic adenocarcinoma: a retrospective cohort study	21
Neurological adverse effects of chimeric antigen receptor T-cell therapy	19
Emergence of an adaptive immune paradigm to explain celiac disease: a perspective on new evidence and implications for future interventions and diagnosis	19
Rare forms of inflammatory myopathies – part I, generalized forms	19
Transcriptional regulation of B cell class-switch recombination: the role in development of noninfectious complications	18
Current treatment options and long-term outcomes in patients with eosinophilic esophagitis	18
Pharmacokinetics and tolerability of prefilled syringe and auto-injector presentations of MSB11456: results of a randomized, single-dose study in healthy adults	18
Direct economic burden 1 year postoperation in Chinese adult patients with chronic rhinosinusitis with nasal polyps	18
Classification and management strategies for paediatric chronic nonbacterial osteomyelitis and chronic recurrent multifocal osteomyelitis	18
Gut immune homeostasis: the immunomodulatory role of Bacillus clausii, from basic to clinical evidence	18
Durability and long-term outcomes of biologic therapies in psoriasis	17
Transcriptomic observations of intra and extracellular immunotherapy targets for pediatric brain tumors	17
Pathophysiology and management of Staphylococcus aureus in nasal polyp disease	17
Inflammatory myopathy in adults, health-related quality of life, and wellbeing: a round trip between immune disease and wellness	17
T-lymphocyte depleted transplants for inborn errors of immunity	17
Eradicating measurable residual disease via immunotherapy to cure acute lymphoblastic leukemia: current status and future directions	16
Chronic obstructive pulmonary disease, biological agents and small molecules: where do we stand?	16
CSE1L as a prognostic biomarker associated with pan cancer immune infiltration and drug sensitivity	16
Recent insights into comorbidities in atopic dermatitis	16
Challenges in uncontrolled asthma in pediatrics: important considerations for the clinician	15
Sicca syndrome/Sjögren’s disease associated with cancer immunotherapy: a narrative review on clinical presentation, biomarkers, and management	15
Safety of JAK inhibitors: focus on cardiovascular and thromboembolic events	15
An updated evaluation of avatrombopag for the treatment of chronic immune thrombocytopenia	15
The intratumor microbiome and cancer immunity: from pathogenesis to therapeutic opportunities through artificial intelligence	15
Personalization of therapy for patients with eosinophilic esophagitis	15
The role of interleukins in pathogenesis and prognosis of atrial fibrillation	15
The functional role and the clinical application of periostin in chronic rhinosinusitis	14
Diagnostic accuracy of QuantiFERON-TB gold plus with chemiluminescence immunoassay: a systematic review and meta-analysis	14
Advancements in immunotherapy for advanced esophageal squamous cell carcinoma: a comprehensive review of current strategies and future directions	14
Patient-centered approaches for patients with systemic autoimmune rheumatic diseases: development and evolution	14
IL-17A in psoriatic arthritis: mechanistic insights, clinical implications, and advances in therapeutic strategies	14
Advances in tumor immunotherapy targeting macrophages	14
Subcutaneous immunoglobulin 16.5% for the treatment of pediatric patients with primary antibody immunodeficiency	13
Temporal trends in anaphylaxis ED visits over the last decade and the effect of COVID-19 pandemic on these trends	13
Interferon beta-1a sc at 25 years: a mainstay in the treatment of multiple sclerosis over the period of one generation	13
Glucocorticoid in systemic lupus erythematosus: the art beyond science	13
Toward a personalized therapy of still’s disease based on immunologic endotypes: a narrative review	13
Insights into the immunological links between dietary habits and asthma	13
Peanut allergy: risk factors, immune mechanisms, and best practices for oral immunotherapy success	13
Recent updates in the diagnosis and management of cryoglobulinemic vasculitis	13
Guidance for stem cell therapy for juvenile systemic sclerosis patients	12
Harnessing the power of AI-based models to accelerate drug discovery against immune diseases	12
The interaction between innate immunity and oral microbiota in oral diseases	12
Current approaches for diagnosis of subclinical pulmonary tuberculosis, clinical implications and future perspectives: a scoping review	12
Updates in toxicities associated with immune checkpoint inhibitors	12
Induction of aquaporins by plasma of patients with systemic lupus erythematosus	12

Skin infections during dupilumab monotherapy in moderate-to-severe atopic dermatitis – a meta-analysis of randomized clinical trials	12
The role of serological biomarkers in the diagnosis and management of autoimmune pancreatitis	12
At the cutting-edge: what’s the latest in imaging to diagnose Sjögren’s disease?	12
How does sleep influence asthma through immunity?	12
New advances on the interaction between internal and external factors in the tumor microenvironment of solid tumors	12
Monoclonal antibodies in diabetic retinopathy	12
Budesonide delayed-release capsules to reduce proteinuria in adults with primary immunoglobulin A nephropathy	11
B cell depletion and inhibition in systemic lupus erythematosus	11
Immunology and targeted therapy in Castleman disease	11
What place will tezepelumab hold in the treatment paradigm in chronic rhinosinusitis?	11
Comparing available JAK inhibitors for treating patients with psoriasis	11
Genetic polymorphisms impacting clinical pharmacology of drugs used to treat inflammatory bowel disease: a precursor to multi-omics approach to precision medicine	11
Basophil activation test in the food allergy clinic: its current use and future applications	11
Pediatric IgG4-related disease: a descriptive review	11
Gut-brain communication in COVID-19: molecular mechanisms, mediators, biomarkers, and therapeutics	11
Hemophagocytic lymphohistiocytosis post chimeric antigen receptor T cell therapies	11
The role of interleukin-15 in the spectrum of inflammatory diseases	11
Definition of severity and treatment response in chronic rhinosinusitis with nasal polyps: a Delphi study among French experts	11
Antiphospholipid antibodies and the risk of adverse pregnancy outcomes in patients with systemic lupus erythematosus: a systematic review and meta-analysis	11
Phosphoinositide-3-kinase δ as an immune check-pathway in cancer Immunology. Therapeutic prospects	10
Transglutaminase 2 in chronic inflammation and fibrosis – a potential novel therapy for stricturing Crohn’s disease	10
Tofacitinib for the treatment of active ankylosing spondylitis in adults	10
Vascular endothelial dysfunction in pediatric rheumatic diseases: a systematic review and meta-analysis	10
Role of tight junction proteins in shaping the immune milieu of malignancies	10
Dysautonomia in systemic lupus erythematosus: when to suspect and how to investigate	10
A review of disease burden and clinical management for generalized pustular psoriasis in China	10
The role of immune reconstitution in relapse after allogeneic hematopoietic stem cell transplantation	10
An update on VEXAS syndrome	10
Characterizing the immune tumor microenvironment in ALK fusion-positive lung cancer: state-of-the-art and therapeutical implications	10
Abdeg technology for the treatment of myasthenia gravis: efgartigimod drug experience	10
Colorectal medullary carcinoma: a pathological subtype with intense immune response and potential to benefit from immune checkpoint inhibitors	10
Individual differences in response to dust-mite-allergen specific immunotherapy in allergic rhinitis: a meta-analysis of randomized controlled trials	10
Sequential immunotherapy for alopecia areata: phase-driven immune rebalancing	10
Update on virus-induced asthma exacerbations	10
Epstein–Barr virus-driven lymphoproliferation in inborn errors of immunity: a diagnostic and therapeutic challenge	10
An evaluation of anifrolumab for use in adults with systemic lupus erythematosus	9
Systemic therapy in juvenile localized scleroderma	9
Advancing kidney protection in type 1 diabetes: insights from emerging therapies in type 2 diabetes and chronic kidney disease	9
Efgartigimod for generalized myasthenia gravis with or without anti-acetylcholine receptor antibodies: a worldwide and Japanese perspective	9
The emerging role of IL-23 in asthma and its clinical implications	9
The clinical role of anakinra in the armamentarium against familial Mediterranean fever	9
The relationship between interleukin 17A rs2275913 gene polymorphism and circulating IL17A levels and disease activity and severity in Egyptian rheumatoid arthritis patients	9
Biomarkers for systemic lupus erythematosus – a focus on organ damage	9
Interleukin 6 in diabetes, chronic kidney disease, and cardiovascular disease: mechanisms and therapeutic perspectives	9
The (apparent) antibody paradox in COVID-19	9
Treatment controversies in spondyloarthritis and psoriatic arthritis: focus on biologics and targeted therapies	9
Treatment strategies for ANCA-associated vasculitides: from standard protocols to future horizons	9
Considerations for managing elderly patients with atopic dermatitis	9
Late effects following hematopoietic cell transplantation for severe combined immunodeficiency: critical factors and therapeutic options	8
In-vitro assays for immuno-oncology drug efficacy assessment and screening for personalized cancer therapy: scopes and challenges	8
Management and treatment optimization of patients with mild to moderate ulcerative colitis	8
Response to letter to the editor: Bradford Hill and breast implant illness: evidence for a causal association with breast implants	8
AQP9 weakens the cytotoxicity of CD8 ⁺ T cells in colon adenocarcinoma by boosting M2 polarization of macrophages under hypoxia conditions	8
The burden of mental health issues in Behçet’s disease: implications for patient quality of life	8
TBXAS1 deficiency: a novel monogenic cause of chronic nonbacterial osteomyelitis responsive to COX inhibitors	8
Lack of association between TNFA and TNFB polymorphisms and the risk of multiple sclerosis: a meta-analysis from 37 studies	8
Potential interactions between STING pathway and the complement system in immune regulation	8
Early diagnosis of systemic sclerosis, where do we stand today?	8
Toward precision in psoriatic arthritis: addressing the challenge of difficult-to-treat disease	8
Evaluating the role of lung ultrasound in the diagnosis of rheumatoid arthritis-interstitial lung disease	8
The clinical management of adult patients with Familial Mediterranean fever	8
Anti-angiotensin 2 receptor 1 antibody (anti-AT1R) and anti-endothelin receptor type a (anti-ETAR) as biomarkers of endothelial dysfunction in systemic sclerosis (SSc) patients	8
Fatigue in ANCA-associated vasculitis (AAV) and systemic sclerosis (SSc): similarities with Myalgic encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). A critical review of the literature	8
Development of a method of nasal secretions sampling for local nasal inflammation studies	8
Pharmacokinetics of a proposed tocilizumab biosimilar (MSB11456) versus US-licensed tocilizumab: results of a randomized, double-blind, single-intravenous dose study in healthy adults	8
Multiple sclerosis-like manifestations in systemic autoimmune and inflammatory disorders: an update	8
Clinical and immunologic implication of neo-osteogenesis in chronic rhinosinusitis	8
Mechanisms and therapeutic potential of epithelial-immune crosstalk in airway inflammation	8
The suitability of treating atopic dermatitis with Janus kinase inhibitors	8
A critical review of belumosudil in adult and pediatric patients with chronic graft-versus-host disease	8
Cross-talk between immune cells and tumor cells in non-Hodgkin lymphomas arising in common variable immunodeficiency	8
Factors that influence infliximab biosimilar trough levels in the pediatric inflammatory bowel disease population	8