OOIR: Observatory of International Research

Papers

(The H4-Index of Chemical Biology & Drug Design is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Cover Image	86
Effect of novel therapeutic medicine swertiamarin from Enicostema axillare in zebrafish infected with Salmonella typhi	67
Computationally Driven Exploration of Novel bis‐Thiadiazole Sulfonamides as Alzheimer's Enzyme Inhibitors: A DFT and Kinetic Perspective	61
Two new compounds from endemic Centaurea paphlagonica (Bornm.) Wagenitz and their cytotoxic activities	52
Folate trapping is lethal to cancer cells	52
Discussion on structure classification and regulation function of histone deacetylase and their inhibitor	48
Estrone analogs as potential inhibitors targeting EGFR‐MAPK pathway in non‐small‐cell lung cancer	48
Discovery of small molecule c‐Maf inhibitors using molecular docking‐based virtual screening, molecular dynamics simulation, and biological evaluation	42
Therapeutic Potential of 6‐Gingerol in Glioma: Mechanistic Insights and Experimental Validation	40
Correction to Silencing PCMT1 enhances the sensitivity of breast cancer cells to paclitaxel through the PI3K	39
Potential Modulatory Effects of Hesperidin on the JAK/STAT Pathway in Mesangial Proliferative Glomerulonephritis	38
Synthesis, Cytotoxic Activity, and Molecular Docking Study of New Thiazole‐Incorporated Indenopyridazine Derivatives as Potential Antiproliferative Drugs	37
Arylnitro monocarbonyl curcumin analogues: Synthesis and in vitro antitubercular evaluation	37
Investigating the Role of Quercetin, an Active Ingredient in Bazhen Decoction, in Targeting CXCL8 to Inhibit Macrophage M2 Polarization and Reshape the Immunological Microenviron	37
Purification and structural analysis of a novel polysaccharide from Rehmannia Radix Praeparata	37
A Comprehensive Analysis on Galantamine Based Hybrids for the Management of Alzheimer's Disease	32
Stigmasterol Inhibits Glioma Metastasis and Angiogenesis by Regulating Macrophage Polarization	32
Computationally Guided Structural Modification of Centaureidin: A Novel Approach for Enhancing Antioxidant and Antitumor Activities for Drug Development	32
Investigation of the Inhibitory Effects and Underlying Mechanisms of Vitexin Derivatives Targeting CDK1 in HCT	31
Design, synthesis, and evaluation of novel bistrifluoromethyl‐based hydrazones as dual inhibitors of acetylcholinesterase and carbonic anhydrase enzymes for Alzheimer's disease	31
Cover Image	31
C2‐linked alkynyl poly‐ethylene glycol(PEG) adenosine conjugates as water‐soluble adenosine receptor agonists	30
The Molecular Mechanism of Resveratrol in the Treatment of Chronic Rhinosinusitis Through a Combination of Network Pharmacology and In Vitro Validation	29
BSV163/DOPE‐mediated TRAIL gene transfection acts synergistically with chemotherapy against cisplatin‐resistant ovarian cancer	29
Hybrid PABA‐glutamic acid conjugated 1,3,5‐triazine derivatives: Design, synthesis, and antimalarial activity screening targeting Plasmodium falciparum dihydro folate reductase enzym	28

TMEM97 knockdown inhibits 5‐fluorouracil resistance by regulating epithelial‐mesenchymal transition and ABC transporter expression via inactivating the Akt/mTOR pathwa	28
	27
	27
A recent update on huprine and its hybrids as a potential multifunctional agent for the treatment of Alzheimer's disease	27