Chemical Biology & Drug Design

Article	Citations
Cover Image	88
Effect of novel therapeutic medicine swertiamarin from Enicostema axillare in zebrafish infected with Salmonella typhi	69
Computationally Driven Exploration of Novel bis‐Thiadiazole Sulfonamides as Alzheimer's Enzyme Inhibitors: A DFT and Kinetic Perspective	62
Estrone analogs as potential inhibitors targeting EGFR‐MAPK pathway in non‐small‐cell lung cancer	56
Therapeutic Potential of 6‐Gingerol in Glioma: Mechanistic Insights and Experimental Validation	55
Correction to Silencing PCMT1 enhances the sensitivity of breast cancer cells to paclitaxel through the PI3K	52
Potential Modulatory Effects of Hesperidin on the JAK/STAT Pathway in Mesangial Proliferative Glomerulonephritis	50
Purification and structural analysis of a novel polysaccharide from Rehmannia Radix Praeparata	42
Design, synthesis, and evaluation of novel bistrifluoromethyl‐based hydrazones as dual inhibitors of acetylcholinesterase and carbonic anhydrase enzymes for Alzheimer's disease	41
A Comprehensive Analysis on Galantamine Based Hybrids for the Management of Alzheimer's Disease	40
Computationally Guided Structural Modification of Centaureidin: A Novel Approach for Enhancing Antioxidant and Antitumor Activities for Drug Development	39
Stigmasterol Inhibits Glioma Metastasis and Angiogenesis by Regulating Macrophage Polarization	39
Synthesis, Cytotoxic Activity, and Molecular Docking Study of New Thiazole‐Incorporated Indenopyridazine Derivatives as Potential Antiproliferative Drugs	38
Arylnitro monocarbonyl curcumin analogues: Synthesis and in vitro antitubercular evaluation	38
Investigating the Role of Quercetin, an Active Ingredient in Bazhen Decoction, in Targeting CXCL8 to Inhibit Macrophage M2 Polarization and Reshape the Immunological Microenviron	34
Discovery of small molecule c‐Maf inhibitors using molecular docking‐based virtual screening, molecular dynamics simulation, and biological evaluation	33
Folate trapping is lethal to cancer cells	33
Targeting the Elongin BC – BC ‐Box Interface: Structural Insights, Peptidic Disruptors and Emergin	32
Investigation of the Inhibitory Effects and Underlying Mechanisms of Vitexin Derivatives Targeting CDK1 in HCT	32
Two new compounds from endemic Centaurea paphlagonica (Bornm.) Wagenitz and their cytotoxic activities	32
Discussion on structure classification and regulation function of histone deacetylase and their inhibitor	31
Propofol Exerts Cerebroprotective Effects Against Cerebral Infarction by Up‐Regulating TRIM67 to Mediate VDAC1	31
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C2‐linked alkynyl poly‐ethylene glycol(PEG) adenosine conjugates as water‐soluble adenosine receptor agonists	29
BSV163/DOPE‐mediated TRAIL gene transfection acts synergistically with chemotherapy against cisplatin‐resistant ovarian cancer	28

The Molecular Mechanism of Resveratrol in the Treatment of Chronic Rhinosinusitis Through a Combination of Network Pharmacology and In Vitro Validation	28
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TMEM97 knockdown inhibits 5‐fluorouracil resistance by regulating epithelial‐mesenchymal transition and ABC transporter expression via inactivating the Akt/mTOR pathwa	27
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Hybrid PABA‐glutamic acid conjugated 1,3,5‐triazine derivatives: Design, synthesis, and antimalarial activity screening targeting Plasmodium falciparum dihydro folate reductase enzym	27
A recent update on huprine and its hybrids as a potential multifunctional agent for the treatment of Alzheimer's disease	26
Why are heterocycles so special in medicinal chemistry?	26
In silico prediction of boiling point, octanol–water partition coefficient, and retention time index of polycyclic aromatic hydrocarbons through machine learning	25
Targeting the Autophagy–Apoptosis Axis in Osteosarcoma: Therapeutic Potential of Biocompounds: A Review	25
Design, synthesis and characterization of ethyl 3‐benzoyl‐7‐morpholinoindolizine‐1‐carboxylate as anti‐tubercular agents: In silico screening for possible target identification	25
Orthogonal threading‐through‐β‐sheet design of lung cancer EGFR extracellular domain‐derived peptidic mimotopes binding to anti‐EGFR antibody	24
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Elucidating the cellular uptake mechanisms of heptamethine cyanine dye analogues for their use as an anticancer drug‐carrier molecule for the treatment of glioblastoma	22
Novel Phenoxyacetic Acid (4‐Aminophenoacetic Acid) Shikonin Ester Kills KRAS Mutant Colon Cancer Cells via Targeting the Akt Allosteric Site	22
A Naturally Derived Glycosylated Oleanolic Acid Derivative Suppresses NF‐κB Translocation and Induces Intrinsic Apoptosis in Lung Adenocarcinoma Cells	22
Paclitaxel may inhibit migration and invasion of gastric cancer cells via nod‐like receptor family pyrin domain‐containing 3/caspase‐1/Gasdermin E mediated pyroptosis pathway	21
Dietary Natural Flavonoids: Intervention for MAO‐B Against Parkinson's Disease	21
Tetrazole: A privileged scaffold for the discovery of anticancer agents	21
miRNAs as key modulators between normal cells and tumor microenvironment interactions	21
Network pharmacology analysis and experimental evaluations of YH complex on androgenetic alopecia by regulating the androgenic‐apoptotic axis	21
Corrigendum	20
Brusatol Exerts Therapeutic Effects in Ulcerative Colitis by Regulating the UBE 3 A ‐	20
Investigating potential mechanisms of vitamin D against thyroid cancer via network pharmacology and experimental validation	20
Synthesis and evaluation of di‐heterocyclic benzazole compounds as potential antibacterial and anti‐biofilm agents against Staphylococcus aureus	20
Machine Learning‐Based Discovery of a Novel Noncovalent MurA Inhibitor as an Antibacterial Agent	20
Curcumin activates the JNK signaling pathway to promote ferroptosis in colon cancer cells	19
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δ‐Tocotrienol Potentiates Breast and Prostate Cancer Cells to Paclitaxel via Suppressing PD‐L1‐Mediated Cancer‐Promoting Signaling	19
Antitumor and antioxidant activities of polysaccharides from the seaweed Durvillaea antarctica	19
Glycyrrhizic acid inhibits DNA damage repair and enhances cisplatin‐induced apoptosis of melanoma cells	19
Plumbagin Triggers STING Pathway Activation to Suppress Non‐Small Cell Lung Cancer Progression	19
Integrated bioinformatics analysis reveals the bidirectional effects of TSPAN6 for cisplatin resistance in lung cancer	19
The designation, synthesis, and affinity determination of affinity peptide for anthrax protective antigen	18
Synthesis and anti‐tumor activity evaluation of 1H‐pyrrolo[2,3‐b]pyridine‐2‐carboxamide derivatives with phenyl sulfonamide groups as potent RSK2 inhibitors	18
Exploring the interactive mechanism of acarbose with the amylase SusG in the starch utilization system of the human gut symbiont Bacteroides thetaiotaomicron through molecular modeli	18
WGX ‐50 Promotes Healthy Ageing in Caenorhabditis elegans : A Combi	18
Chemical synthesis, biological activities, and molecular simulations of novel sulfonylurea compounds bearing ortho‐alkoxy substitutions	17
2, 4, 5‐Trideoxyhexopyranosides derivatives of diphyllin: Synthesis and anticancer activity	17
Kisspeptin‐10 Improves Gestational Diabetes Mellitus Symptoms in Rats by Suppressing Insulin Resistance in Placental Trophoblast Cells by Activating the Cyclic AMP/Protein Kinase A Pathway	17
Progress of SARS‐CoV‐2 Main protease peptide‐like inhibitors	17
Small Molecule Inhibitors Targeting Cdc2‐Like Kinase 4: Advances, Challenges, and Opportunities	16
Exploring the Artificial Intelligence and Its Impact in Pharmaceutical Sciences: Insights Toward the Horizons Where Technology Meets Tradition	16
Molecular Mechanisms and Efficacy of Tislelizumab, a PD ‐1 Inhibitor Developed in China, in Non‐Small Cell Lung Cancer	16
Dexmedetomidine attenuates myocardial ischemia–reperfusion injury in hyperlipidemic rats by inhibiting inflammation, oxidative stress and NF‐κB	16
Praeruptorin A inhibits the activation of NF‐κB pathway and the expressions of inflammatory factors in poly (I:C)‐induced RAW264.7 cells	16
An appraisal on synthetic and pharmaceutical perspectives of quinoxaline 1,4‐di‐N‐oxide scaffold	16
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Glabridin inhibits urothelial bladder carcinoma cell growth in vitro and in vivo by inducing cell apoptosis and cell cycle arrest	15
In vitro and in vivo antileishmanial activity of the hanging sedge flavonoids based on bio‐ guided fractionation assay	15
Quercetin Prevents Hyperuricemia Associated With Gouty Arthritis by Inactivating the NLRP3/NF‐κB Signaling Pathway	15

Lycopersene: A review on extraction, identification and purification and applications	15
Design, synthesis, in vitro evaluation, and molecular modeling studies of N‐substituted benzomorphans, analogs of LP2, as novel MOR ligands	15
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Structural and dynamic investigation of non‐synonymous variations in Renin–AGT complex revealed altered binding via hydrogen‐bonding network reprogramming to accelerate the hypertension pathway	15
Network pharmacology and in vitro experiments reveal sophoridine‐induced apoptosis and G1 phase arrest via ROS‐dependent PI3K/Akt/FoxO3a pathway	14
Herbacetin Inhibits Human Fructose 1,6‐Bisphosphatase Among a Panel of Chromone Derivatives and Pyrazoles, Demonstrating Positive Effects on Insulin‐Resistant HepG2 Cells	14
From Pharmacophore Models to Lead Compounds: Construction and Activity Evaluation of Novel Indoleamine 2,3‐Dioxygenase‐1 Inhibitors	14
LaSOM335, active against bladder cancer cells, interferes withLet‐60(hRas) and reducesCD73 expression/activity	14
Isoxazole and Pyrazole Derivatives of 28‐Oxo‐Allobetulone Target Viral Membrane Glycoprotein Hemagglutinin	14
Identification of miR‐3182 and miR‐3143 target genes involved in the cell cycle as a novel approach in TNBC treatment: A systems biology approach	13
Discovery of novel 1,3,5‐triazines as potent antibacterial agent against urinary tract infection‐causing clinical isolates of Escherichia coli via inhibition of DNA Gyrase	13
Exploring Thiazole‐Based Heterocycles: Synthesis, Bioactivity, and Molecular Docking for Antimicrobial Applications	13
Design, synthesis, antibacterial activity evaluation and molecular docking study of pleuromutilin derivatives bearing amide side chains	13
A comprehensive review on the research progress of PTP1B inhibitors as antidiabetics	13
Bruceine A Suppresses Triple‐Negative Breast Cancer Growth and Metastasis by Inducing GPX4 ‐Dependent Ferroptosis via Ubiquitin–Proteasome‐Mediated D	13
Design, Synthesis and Biological Evaluation of Aminoalkylated Paeonol Chalcone Derivatives	13
Synthetic corticotropins and the GABA‐receptor system: Direct and delayed effects	13
Click chemistry beyond metal‐catalyzed cycloaddition as a remarkable tool for green chemical synthesis of antifungal medications	13
Therapeutic efficacy of caffeic acid phenethyl ester in cancer therapy: An updated review	13
Substrate‐based synthetic strategies and biological activities of 1,3,4‐oxadiazole: A review	13
The medicinal chemistry of piperazines: A review	12
KH‐17, a simplified derivative of bongkrekic acid, weakly inhibits the mitochondrial ADP/ATP carrier from both sides of the inner mitochondrial membrane	12
Anticancer mechanisms of β‐carbolines	12
Baicalein Targets MAPK9 to Induce Apoptosis of Hepatocellular Carcinoma Cells	12
A Comprehensive Review on the Advancements of Dual COX‐2/5‐LOX Inhibitors as Anti‐Inflammatory Drugs	12
Targeting Cancer Cell Proliferation Using Piperazine‐Linked Quinolinequinones: Mechanism and Metabolic Profile	12
Curcumin Regulates Microglia Polarization to Alleviate Ischemic Stroke by Targeting microRNA‐205‐5p/Kruppel‐Like Factor 2 (KLF2)/Activating Transcription Factor 2 (ATF2) Axis	12
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Berberine Ameliorates Pulmonary Fibrosis by Inactivating the Thrombospondin 2/Smad Homolog 2/3 Pathway	12
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Correction to Plumbagin's Antiproliferative Mechanism in Human Cancer Cells: A Copper‐Dependent Cytotoxic Approach	11
Design, Synthesis, and Biological Evaluation of New Benzimidazole‐1,2,4‐Triazole Derivatives as Potential Anticancer Agents	11
Multi‐fluorine labeled indanone derivatives as potential MRI imaging probes for β‐Amyloid plaques	11
Synthesis of Novel Soritin Sulfonamide Derivatives as Potential α‐Glucosidase Inhibitor and Their Molecular Docking Studies	11
Pyrrole‐Tethered Bisbenzoxazole Derivatives: Apoptosis‐Inducing Agents Targeting Breast Cancer Cells	11
Identification of Potent Leucine‐Rich Repeat Kinase 2 Inhibitors by Virtual Screening and Biological Evaluation	11
Spalt‐Like Transcription Factor 4 Mediates Fatty Acid Oxidation to Foster 5‐Fluorouracil Resistance in Gastric Cancer Cells	11
β‐elemene enhances cisplatin sensitivity of non‐small cell lung cancer cells via the miR‐17‐5p/STAT3 axis	11
Novel Benzimidazole‐Urea Phenylalanine Hybrids as Dual‐Acting Antimicrobial and Anticancer Agents: In Silico and Biological Evaluation	11
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Identification of Mitophagy‐Related Genes With Diagnostic Value in Atherosclerosis Using Bioinformatics Analysis and Experiment Validation	11
Madecassoside Induces Apoptosis and Inhibits Migration by Regulating ROS ‐Mediated Signaling Pathways in MDA	10
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Plumbagin induces apoptosis, cell cycle arrest, and inhibits protein synthesis in LoVo colon cancer cells: A proteomic analysis	10
Optimized synthesis, polymer conjugation, and proof‐of‐concept studies of the gd‐IgA1 epitope for antibody‐scavenging therapies in IgA nephropathy	10
Apelin‐13's Actions in Controlling Hypertension‐Related Cardiac Hypertrophy and the Expressions of Inflammatory Cytokines	10
Syringic acid suppresses ferroptosis of skeletal muscle cells to alleviate lower limb ischemia/reperfusion injury in mice via the HMGB1 pathway	10
EGFR degraders in non‐small‐cell lung cancer: Breakthrough and unresolved issue	10
Pyrimidine derivatives as EGFR tyrosine kinase inhibitors in non‐small‐cell lung cancer: A comprehensive review	10
Network Pharmacology, Machine Learning, Molecular Docking, and Cell Experiments Reveal the Therapeutic Mechanism of Radix Rehmanniae Praeparata in Psoriasis In Vitro	10
Correction to “Synthesis, Cytotoxic Activity, and Molecular Docking Study of New Thiazole‐Incorporated Indenopyridazine Derivatives as Potential Antiproliferative Drugs”	10
Synthesis and preliminary evaluation of benzylaminoimidazoline derivatives as novel norepinephrine transporter ligands	10
Identification of a novel ALDH1A3‐selective inhibitor by a chemical probe with unrelated bioactivity: An approach to affinity‐based drug target discovery	10
Atropisomerism transforming anti‐cancer drug discovery	10
Structure‐Based Design of 2‐Aminopyrazolpyrimidopyridone Derivatives as New Rearranged During Transfection (RET) Kinase Inhibitors	10
The Therapeutic Effect and Mechanism of Vismodegib on COPD : Focusing on NETs and Macrophage Polar	10
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Screening and introduction of key cell cycle microRNAs deregulated in colorectal cancer by integrated bioinformatics analysis	10
Synthesis of novel 5‐amido‐2‐carboxypyrazines as inhibitors of the type three secretion system of Salmonella enterica serovar Typhimurium	10
Investigation of Potential Inhibitors of N‐Myristoyltransferase in Leishmania amazonensis: A Computational and Experimental Study	10
Kaempferol exerts antioxidant effects in age‐related diminished ovarian reserve by regulating the HSP90/NRF2 pathway	10
Curcumin inhibits malignant behavior of colorectal cancer cells by regulating M2 polarization of tumor‐associated macrophages and metastasis associated in colon cancer 1 (MACC1)	10
Current Challenges With Highly Active Antiretroviral Therapy and New Hope and Horizon With CRISPR‐CAS9 Technology for HIV Treatment	10
NMC‐4 Ameliorates Depression‐Like Behavior and Neuroinflammation Caused by Chronic Unpredictable Mild Stress	9
Systematic profiling of Taxol resistance and sensitivity to tubulin missence mutations at molecular and cellular levels	9
Therapeutic implications of crocin in Parkinson's disease: A review of preclinical research	9
Design and Synthesized 3,4‐Dimethoxybenzene‐Based Fibrate Derivatives as Potential Hypolipidemic and Liver Protection Agents	9
Paeoniflorin Ameliorates Osteoarthritis via Ring Finger Protein 216/Optineurin‐Mediated Autophagy Activation in Chondrocytes	9
Local anaesthetic procaine derivatives protect rat against diabetic nephropathy via inhibition of DPP‐4, inflammation and oxidative stress	9
Chromone Derivatives as a Novel NOX4 Inhibitor: Design, Synthesis, and Regulation of ROS in Renal Fibroblast	9
Combination of fenchone and sodium hyaluronate ameliorated constipation‐predominant irritable bowel syndrome and underlying mechanisms	9
The evaluation of isatin analogues as inhibitors of monoamine oxidase	9
Structural Insights Into Papain‐Derived Synthetic Antibacterial Peptides for Targeting Klebsiella pneumoniae	9
Correction to “Targeting the Autophagy–Apoptosis Axis in Osteosarcoma: Therapeutic Potential of Biocompounds: A Review”	9
IGF2BP3 loss inhibits cell progression by upregulating has_circRNA_103820, and hsa_circRNA_103820‐encoded peptide inhibits cell progression by inactivating the AKT pathway in lung cancer	9
Sinigrin improves cerebral ischaemia‐reperfusion injury by inhibiting the TLR4 pathway‐mediated oxidative stress	9
Exploring the cytotoxic potential of biflavones of Araucaria cunninghamii: Precise identification combined by LC‐HRMS‐metabolomics and database mining, targeted isolation, network pharmacology,	9
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A single‐chain variable fragment‐anticancer lytic peptide (scFv‐ACLP) fusion protein for targeted cancer treatment	9
The mannose‐binding protein from Agaricus bisporus inhibits the growth of MDA‐MB‐231 spheroids	9

Exploring Flavonoids as Regulators of MMP‐2 and MMP‐9 in Cancer Pathogenesis	9
Dexmedetomidine Inhibits Ferroptosis by Regulating the SRY‐Box Transcription Factor 9/Divalent Metal Transporter‐1 Axis to Alleviate Cerebral Ischemia/Reperfusion Injury	9
Pioneering QSAR Modeling Study of FAP ‐Targeting Radiopharmaceuticals Used in Oncology	9
Identification of 5‐(3‐(methylsulfonyl)phenyl)‐3‐(4‐(methylsulfonyl)phenyl)‐3H‐imidazo[4,5‐b]pyridine as novel orally bioavailable and metabolically stable antimalarial compou	8
Myoinositol and methyl stearate increases rifampicin susceptibility among drug‐resistant Mycobacterium tuberculosis expressing Rv1819c	8
Bioinformatic Analysis of the Protective Effects of Dexmedetomidine and Thrombopoietin Against Hypoxia/Reoxygenation‐Induced Injury in AC16 Cells	8
Amentoflavone attenuates cell proliferation and induces ferroptosis in human gastric cancer by miR‐496/ATF2 axis	8
Design and Synthesis of 1,4‐Diformyl‐Piperazine Ferrostatin‐1 Derivatives as Novel Ferroptosis Inhibitors	8
Research progress on the P2X7 receptor in liver injury and hepatocellular carcinoma	8
High‐Throughput Platform for Discovery of Chemical Inhibitors of Heat Shock Protein 70 (Hsp70): Adaptation for the Specialized Bacterial HscA–HscB–IscU Complex	8
In silico optimization of analogs derived pro‐adrenomedullin peptide to evaluate antimicrobial potential	8
Discovery and evaluation of biphenyl derivatives of 2‐iminobenzimidazoles as prototype dual PTP1B inhibitors and AMPK activators with in vivo antidiabetic activity	8
Spacered With Tetrazole Oleanolic and Ursolic Indolo‐Acids Are Strong Inhibitors of α‐Glucosidase	8
Cytotoxic activity of quinolinequinones in cancer: In vitro studies, molecular docking, and ADME/PK profiling	8
Study on the molecular mechanism of dihydromyricetin in alleviating liver cirrhosis based on network pharmacology	8
Exendin‐4: A potential therapeutic strategy for Alzheimer's disease and Parkinson's disease	8
Transformer‐Based Model for Drug Design and Therapy Response Prediction	8
Medicarpin suppresses proliferation and triggeres apoptosis by upregulation of BID, BAX, CASP3, CASP8, and CYCS in glioblastoma	8
Puerarin Decreases the Expression of FUS‐Dependent MAPK4 to Inhibit the Development of Triple‐Negative Breast Cancer	8
Hsa‐miR‐503‐5p regulates CTDSPL to accelerate cisplatin resistance and angiogenesis of lung adenocarcinoma cells	8
Discovery a series of novel inhibitors of human dihydroorotate dehydrogenase: Biological activity evaluation and molecular docking	8
Berberine attenuates cognitive dysfunction and hippocampal apoptosis in rats with prediabetes	8
Heterocyclic and non‐heterocyclic arena of monocarboxylate transporter inhibitors to battle tumorigenesis	8
An in silico comparative study of curcumin and 2‐deoxyuridine nucleoside derivatives: Reveals the role of angiogenin in ER stress‐induced apoptosis signaling	8
Propofol inhibits the proliferation, invasion, migration, and angiogenesis of oral squamous cell carcinoma through circ_0008898‐mediated pathway	8
Correction to “Nanoemulsion Based Lipid Nanoparticles for Effective Demethylcantharidin Delivery to Cure Liver Cancer”	8
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Long noncoding RNA SNHG7‐miRNA‐mRNA axes crosstalk with oncogenic signaling pathways in human cancers	8
Identification and Biological Evaluation of ( 4 H ‐Thieno[3,2‐ b ]indol‐3‐y	8
The Immuno‐Metabolic Crosstalk in Lung Squamous Cell Carcinoma: Prognostic Insights and Therapeutic Clues	8
Ferulic Acid Inhibits Partial Epithelial‐Mesenchymal Transition in Renal Tubular Epithelial Cells and Mitigates Renal Interstitial Fibrosis by Regulating the HIF‐1α/Twist Signaling Pathway	8
Correction to Analysis of bioactive compounds using LC – ESI – MS	8
Issue Information	8
Synthesis and Preliminary Anticancer Evaluation of 4‐C Derivatives of Diphyllin	8
Computational prediction of Lee retention indices of polycyclic aromatic hydrocarbons by using machine learning	8
Design of Hybrid Bioactive Peptides Derived From Cecropin and Cathepsin for Therapeutic Application	8
Elucidation of the mechanisms and molecular targets of KeChuanLiuWei‐Mixture for treatment of severe asthma based on network pharmacology	8
Comment on “Integrative Analysis of Ex Vivo Studies and Microarray Reveals the Novel Inhibitor Effects of Trehalose on the Pathogenesis of Pterygium”	8
Synthesis and antiglycation activity of 3‐phenacyl substituted thiazolium salts, new analogs of Alagebrium	8
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Methyltransferase METTL3‐mediated maturation of miR‐4654 facilitates high glucose‐induced apoptosis and oxidative stress in lens epithelial cells via decreasing SOD2	7
Tetrahydropalmatine Alleviates Osteoarthritis‐Associated Pain and Inflammation by Suppressing KDM4A / MDM2	7
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Transition metal complexes of hydrazones as potential antimicrobial and anticancer agents: A short review	7
Discovering novel derivatives of STAT3 and HDAC inhibitors with anti‐tumor activity	7
Paeoniflorin Alleviates Pulmonary Arterial Hypertension by Suppressing TRIM24 ‐Mediated SIRT1 Ubiq	7
Quinoline‐based heterocyclic hydrazones: Design, synthesis, anti‐plasmodial assessment, and mechanistic insights	7
Ginsenoside Rg3 alleviates the migration, invasion, and angiogenesis of lung cancer cells by inhibiting the expressions of cyclooxygenase‐2 and vascular endothelial growth factor	7
Downregulation of MDM2 by small interference RNA induces apoptosis and sensitizes MCF‐7 breast cells to resveratrol	7
Sulfonyl Hydrazone Derivatives Targeting Glutathione Reductase: A Potential Strategy for Redox Modulation in Cancer	7
Ganoderic acid A improves osteoarthritis by regulating RANKL/OPG ratio	7
Synthesis and Investigation of Peptide–Drug Conjugates Comprising Camptothecin and a Human Protein‐Derived Cell‐Penetrating Peptide	7
Ligand and structure based hierarchical virtual screening cascade for finding novel epidermal growth factor receptor inhibitors	7
A highly bioavailable curcumin formulation ameliorates inflammation cytokines and neurotrophic factors in mice with traumatic brain injury	7
Could natural terpenes be an alternative for the treatment of neglected tropical diseases?	7
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Quercetin inhibits breast cancer cell proliferation and survival by targeting Akt/mTOR/PTEN signaling pathway	7
Asiatic acid inhibits rheumatoid arthritis fibroblast‐like synoviocyte growth through the Nrf2/HO‐1/NF‐κB signaling pathway	7
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Structural modification of 2‐phenylquinoline‐4‐carboxylic acid containing SIRT3 inhibitors for the cancer differentiation therapy	7
Xanthones as potential α‐glucosidase non‐competition inhibitors: Synthesis, inhibitory activities, and in silico studies	7
Design, Hemisynthesis, Characterization, Molecular Docking, and Dynamics Evaluation of Novel Totarol‐1,2,3‐Triazole Derivatives as Leishmaniasis and Toxoplasmosis Agents	7
Thienopyrimidine: Unveiling the Versatile Potential of a Promising Heterocyclic Scaffold in Drug Discovery	7
Some 2‐[4‐(1H‐benzimidazol‐1‐yl) phenyl]‐1H‐benzimidazole derivatives overcome imatinib resistance by induction of apoptosis and reduction of P‐glycoprotein activity	7
Dehydroepiandrosterone‐α‐2‐Deoxyglucoside Exhibits Enhanced Anticancer Effects in MCF‐7 Breast Cancer Cells and Inhibits Glucose‐6‐Phosphate Dehydrogenase Activity	7
Pyrrole‐based EGFR inhibitors for the treatment of NCSLC: Binding modes and SARs investigations	7
Anti‐metastatic Effects of Bee Venom and Melittin in Breast Cancer Cells by Upregulation of BRMS1 and DRG1 Genes	7
Nardosinone suppresses monoiodoacetate‐induced osteoarthritis in rats: The key role of the miR‐218‐5p/NUMB axis	7
Role of calcium dysregulation in Alzheimer's disease and its therapeutic implications	7
Curcumin affects apoptosis of colorectal cancer cells through ATF6‐mediated endoplasmic reticulum stress	7
New pyrrolidine‐carboxamide derivatives as dual antiproliferative EGFR/CDK2 inhibitors	7
Nesfatin‐1 Reduces Cholic Acid‐Induced Intrahepatic Cholestasis of Pregnancy by Regulating the General Control Nonderepressible 2/Eukaryotic Initiation Factor 2α Pathway	7
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Geraniol protects hippocampal CA1 neurons and improves functional outcomes in global model of stroke in rats	7
Transethosomes: Cutting edge approach for drug permeation enhancement in transdermal drug delivery system	7
Arctigenin Modulates Adipogenic‐Osteogenic Balance in the Bone Marrow Microenvironment of Ovariectomized Rats via the MEK1/PPARγ/Wnt/β‐Catenin Pathway	7
Design and synthesis of isatin derivatives as effective SARS‐CoV‐2 3CL protease inhibitors	7
Antiproliferative Activity and Target Analysis of 18β‐Glycyrrhetinic Acid Derivatives Modified With α, β‐Unsaturated Carbonyl Groups	7
Development of potent inhibitors by fragment‐linking strategies	7
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Imino and Thioureidic Derivatives as New Tools for Alzheimer's Disease: Preliminary Studies	6
Rutaecarpine Attenuates Ovalbumin‐Induced Asthma in Mice by Regulating the NF ‐ κB Pathway	6
Polysaccharide‐modified liposomes and their application in cancer research	6
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Correction to “Antibacterial and antitubercular evaluation of dihydronaphthalenone‐indole hybrid analogs”	6
SAIAME: Semi‐Parameter Adaptation Information‐Assisted Multi‐Objective Evolutionary for Protein‐Ligand Docking	6
Retracted: Isolation and purifications of an ambuic acid derivative compound from marine algal endophytic fungi Talaromyces flavus that induces apoptosis in MDA‐MB‐231 cancer	6
Tanshinone IIA Reverses Osteogenic Differentiation of Bone Marrow Mesenchymal Stromal Cells Impaired by Glucocorticoids via the ERK1/2‐CREB Signaling Pathway	6
A systematic literature review for the prediction of anticancer drug response using various machine‐learning and deep‐learning techniques	6
Deep Learning for Drug–Target Interaction Prediction: A Comprehensive Review	6
Astragaloside IV restrains pulmonary fibrosis progression via the circ_0008898/miR‐211‐5p/HMGB1 axis	6
Assessment of the anti‐inflammatory mechanism of quercetin 3,7‐dirhamnoside using an integrated pharmacology strategy	6
Brusatol induces ferroptosis to inhibit hepatocellular carcinoma progression by targeting ATF3	6
ANKRD22 promotes M2 polarization in lung adenocarcinoma macrophages via the glycolytic pathway	6
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