Chinese Medicine

Article	Citations
Integrated strategy of network analysis prediction and experimental validation to elucidate the possible mechanism of compound Turkish gall ointment in treating eczema	143
Protective effects of Notoginsenoside R2 on reducing lipid accumulation and mitochondrial dysfunction in diabetic nephropathy through regulation of c-Src	84
Pharmacological activity and clinical application analysis of traditional Chinese medicine ginger from the perspective of one source and multiple substances	81
Coix seed oil alleviates synovial angiogenesis through suppressing HIF-1α/VEGF-A signaling pathways via SIRT1 in collagen-induced arthritis rats	71
Effects of genus Epimedium in the treatment of osteoarthritis and relevant signaling pathways	70
Distinct mechanisms of electroacupuncture and manual acupuncture in modulating hypothalamic GnRH–tanycyte unit function of polycystic ovary syndrome	69
Efficacy and compatibility mechanism of bear bile powder in Shexiang Tongxin dropping pills for acute myocardial infarction treatment	64
Natural products provide a new perspective for anti-complement treatment of severe COVID-19: a review	60
Effects of antioxidants on diabetic kidney diseases: mechanistic interpretations and clinical assessment	58
Chinese integrated guideline on the management of gastric precancerous conditions and lesions	57
Shikonin attenuates rheumatoid arthritis by targeting SOCS1/JAK/STAT signaling pathway of fibroblast like synoviocytes	53
Correction: Magnolia kobus DC. suppresses neointimal hyperplasia by regulating ferroptosis and VSMC phenotypic switching in a carotid artery ligation mouse model	52
Aidi injection inhibits the migration and invasion of gefitinib-resistant lung adenocarcinoma cells by regulating the PLAT/FAK/AKT pathway	50
Network pharmacology: a crucial approach in traditional Chinese medicine research	48
Traditional Chinese Medicine in nonalcoholic fatty liver disease: molecular insights and therapeutic perspectives	48
Construction of machine learning-based models for screening the high-risk patients with gastric precancerous lesions	48
Pharmacological activities and molecular mechanisms of Pulsatilla saponins	45
Shirebi granules ameliorate acute gouty arthritis by inhibiting NETs-induced imbalance between immunity and inflammation	45
Saikosaponin D exerts antidepressant effect by regulating Homer1-mGluR5 and mTOR signaling in a rat model of chronic unpredictable mild stress	45
Chrysanthemum morifolium Ramat extract and probiotics combination ameliorates metabolic disorders through regulating gut microbiota and PPARα subcellular localization	42
The key issues and development strategy of Chinese Classical Formulas pharmaceutical preparations	41
Technical guidelines for risk assessment of heavy metals in traditional Chinese medicines	41
Gegen Qinlian standard decoction alleviated irinotecan-induced diarrhea via PI3K/AKT/NF-κB axis by network pharmacology prediction and experimental validation combination	41
Liver metabolomics reveals potential mechanism of Jieduan-Niwan formula against acute-on-chronic liver failure (ACLF) by improving mitochondrial damage and TCA cycle	39
Quercetin inhibits caspase-1-dependent macrophage pyroptosis in experimental folic acid nephropathy	38

Potential of natural products and gut microbiome in tumor immunotherapy	37
Correction: Natural products: potential drugs for the treatment of renal fibrosis	37
Systems pharmacology and transcriptomics reveal the mechanisms of Sanhuang decoction enema in the treatment of ulcerative colitis with additional Candida albicans infection	36
Traditional herbal formula Wu-Mei-Wan alleviates TNBS-induced colitis in mice by inhibiting necroptosis through increasing RIPK3 O-GlcNAcylation	35
New bakuchiol dimers from Psoraleae Fructus and their inhibitory activities on nitric oxide production	34
Anti-malarial drug: the emerging role of artemisinin and its derivatives in liver disease treatment	34
Si-Wu-Tang ameliorates fibrotic liver injury via modulating intestinal microbiota and bile acid homeostasis	34
The therapeutic promises of Lianhuaqingke in the mice model of coronavirus pneumonia (HCoV-229E and SARS-CoV-2)	33
Exploring biological basis of Syndrome differentiation in coronary heart disease patients with two distinct Syndromes by integrated multi-omics and network pharmacology strategy	32
Bletilla striata polysaccharide cryogel scaffold for spatial control of foreign-body reaction	31
Roles of reactive oxygen species, mitochondrial membrane potential, and p53 in evodiamine-induced apoptosis and G2/M arrest of human anaplastic thyroid carcinoma cells	30
Paclitaxel combined with Compound K inducing pyroptosis of non-small cell lung cancer cells by regulating Treg/Th17 balance	29
“Qi Nan” agarwood restores podocyte autophagy in diabetic kidney disease by targeting EGFR signaling pathway	29
Shaoyao Decoction reduced T lymphocyte activation by regulating of intestinal flora and 5-hydroxytryptamine metabolism in ulcerative colitis	29
Comparative efficacy of Chinese patent medicines in patients with carotid atherosclerotic plaque: a Bayesian network meta− analysis	29
Total iridoid glycoside extract of Lamiophlomis rotata (Benth) Kudo accelerates diabetic wound healing by the NRF2/COX2 axis	29
Tanreqing injection inhibits dengue virus encephalitis by suppressing the activation of NLRP3 inflammasome	28
Development of an interpretable machine learning model associated with genetic indicators to identify Yin-deficiency constitution	27
Zhi-Kang-Yin formula attenuates high-fat diet-induced metabolic disorders through modulating gut microbiota-bile acids axis in mice	26
Geniposide for treating atherosclerotic cardiovascular disease: a systematic review on its biological characteristics, pharmacology, pharmacokinetics, and toxicology	26
Metabolomics and proteomics analyses of Chrysanthemi Flos: a mechanism study of changes in proteins and metabolites by processing methods	26
Sound as a bell: a deep learning approach for health status classification through speech acoustic biomarkers	26
Siwu decoction mitigates radiation-induced immune senescence by attenuating hematopoietic damage	24
Unveiling correlations between aristolochic acids and liver cancer: spatiotemporal heterogeneity phenomenon	24
Temporal, spatial and demographic distributions characteristics of COVID-19 symptom clusters from chinese medicine perspective: a systematic cross-sectional study in China from 2019 to 2023	24
Indole-3-carbinol alleviates allergic skin inflammation via periostin/thymic stromal lymphopoietin suppression in atopic dermatitis	24
An anti-inflammatory and anti-fibrotic proprietary Chinese medicine nasal spray designated as Allergic Rhinitis Nose Drops (ARND) with potential to prevent SARS-CoV-2 coronavirus infection by targetin	23
Pedunculoside alleviates cognitive deficits and neuronal cell apoptosis by activating the AMPK signaling cascade	23
Efficacy and mechanisms of traditional Chinese medicine for COVID-19: a systematic review	23
The tibetan medicine Zuozhu-Daxi can prevent Helicobacter pylori induced-gastric mucosa inflammation by inhibiting lipid metabolism	23
Acupuncture may play a key role in anti-depression through various mechanisms in depression	23
Liquiritin exhibits anti-acute lung injury activities through suppressing the JNK/Nur77/c-Jun pathway	22
Exploration of the mechanisms underlying the beneficial effect of Luo Tong formula on retinal function in diabetic rats via the “gut microbiota–inflammation–retina” axis	22
The relationship between gut microbiota and susceptibility to type 2 diabetes mellitus in rats	22
Metabolomics analyses of traditional Chinese medicine formula Shuang Huang Lian by UHPLC-QTOF-MS/MS	22
Effect of ginsenoside compound K on alleviating colitis via modulating gut microbiota	21
Exploring the active components and potential mechanisms of Rosa roxburghii Tratt in treating type 2 diabetes mellitus based on UPLC-Q-exactive Orbitrap/MS and network pharmacology	21
Jin-Tian-Ge ameliorates ovariectomy-induced bone loss in rats and modulates osteoblastogenesis and osteoclastogenesis in vitro	21
Study on basic and clinical application of Shufeng Jiedu Capsule in treating respiratory tract infection	21
Carbohydrates and ginsenosides in shenmai injection jointly improve hematopoietic function during chemotherapy-induced myelosuppression in mice	21
Validation of evidence-based questionnaire for TCM syndrome differentiation of heart failure and evaluation of expert consensus	21
Reporting quality of sham needles used as controls in acupuncture trials: a methodological evaluation	20
Fushenmu treatment ameliorates RyR2 with related metabolites in a zebrafish model of barium chloride induced arrhythmia	20
Mineral medicine: from traditional drugs to multifunctional delivery systems	20
Eryngium caeruleum: an update on ethnobotany, phytochemistry and biomedical applications	20
Taxillus chinensis (DC.) Danser: a comprehensive review on botany, traditional uses, phytochemistry, pharmacology, and toxicology	20
Pulsatilla Decoction and its bioactive component β-peltatin induce G2/M cell cycle arrest and apoptosis in pancreatic cancer	20
Multi-target regulatory mechanism of Yang Xin Tang − a traditional Chinese medicine against dementia	20
Research on the interaction of astragaloside IV and calycosin in Astragalus membranaceus with HMGB1	19
Inhibitory effect of Isatis tinctoria L. water extract on DNCB-induced atopic dermatitis in BALB/c mice and HaCaT cells	19

Exploring the potential use of Chinese herbs in regulating the inflammatory microenvironment of tumours based on the concept of ‘state-target identification and treatment’: a scooping review	19
A review on the research progress of traditional Chinese medicine with anti-cancer effect targeting ferroptosis	19
Zhuifeng Tougu capsules in the treatment of knee osteoarthritis (cold dampness obstruction syndrome): a randomized, double blind, multicenter clinical study	18
Effect of traditional chinese medicine (TCM) and its fermentation using Lactobacillus plantarum on ceftriaxone sodium-induced dysbacteriotic diarrhea in mice	18
Shengui Sansheng San alleviates the worsening of blood–brain barrier integrity resulted from delayed tPA administration through VIP/VIPR1 pathway	18
Kai-Xin-San protects against mitochondrial dysfunction in Alzheimer’s disease through SIRT3/NLRP3 pathway	18
Shen-Zhi-Ling oral liquid ameliorates cerebral glucose metabolism disorder in early AD via insulin signal transduction pathway in vivo and in vitro	18
DNA barcoding: an efficient technology to authenticate plant species of traditional Chinese medicine and recent advances	17
Chinese herbal medicines in the treatment of ulcerative colitis: a review	17
The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin	17
Exploring the effect of Yinzhihuang granules on alcoholic liver disease based on pharmacodynamics, network pharmacology and molecular docking	17
Traditional Chinese medicine promotes bone regeneration in bone tissue engineering	17
Effects of Shenling Baizhu powder on pyrotinib-induced diarrhea: analysis of gut microbiota, metabonomics, and network pharmacology	17
A comprehensive review on traditional uses, phytochemistry and pharmacological properties of Paeonia emodi Wall. ex Royle: current landscape and future perspectives	17
Effects of Chinese medicine for COVID-19 rehabilitation: a multicenter observational study	17
Isoforskolin modulates AQP4-SPP1-PIK3C3 related pathway for chronic obstructive pulmonary disease via cAMP signaling	17
Revealing potential anti-fibrotic mechanism of Ganxianfang formula based on RNA sequence	16
Honokiol alleviates LPS-induced acute lung injury by inhibiting NLRP3 inflammasome-mediated pyroptosis via Nrf2 activation in vitro and in vivo	16
FVTF inhibits hepatocellular carcinoma stem properties via targeting DNMT1/miR-34a-5p/FoxM1 axis	16
Antiviral activities of Artemisia vulgaris L. extract against herpes simplex virus	16
Herbal formula Huangqi Guizhi Wuwu decoction attenuates paclitaxel-related neurotoxicity via inhibition of inflammation and oxidative stress	16
Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ1-42-induced Alzheimer’s disease mice and glutamate-injured HT22 cells	16
Traditional Chinese medicine for colorectal cancer treatment: potential targets and mechanisms of action	16
Exploration of the anti-hyperuricemia effect of TongFengTangSan (TFTS) by UPLC-Q-TOF/MS-based non-targeted metabonomics	16
Molecular quantification of fritillariae cirrhosae bulbus and its adulterants	16
Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway	16
Biosynthesis and signal transduction of plant growth regulators and their effects on bioactive compound production in Salvia miltiorrhiza (Danshen)	16
CRISPR-Cas gene editing technology and its application prospect in medicinal plants	16
Natural drug sources for respiratory diseases from Fritillaria: chemical and biological analyses	16
Traditional Chinese Medicine for adjuvant treatment of breast cancer: Taohong Siwu Decoction	15
Correction: Shengjiang San alleviated sepsis-induced lung injury through its bidirectional regulatory effect	15
Natural products: potential drugs for the treatment of renal fibrosis	15
Puerarin: a hepatoprotective drug from bench to bedside	15
Correction to: Immunomodulatory effects of a new whole ingredients extract from Astragalus: a combined evaluation on chemistry and pharmacology	15
Mentha haplocalyx Briq. (Mint): a comprehensive review on the botany, traditional uses, nutritional value, phytochemistry, health benefits, and applications	15
Bushen-Yizhi formula ameliorates mitochondrial dysfunction and oxidative stress via AMPK/Sirt1 signaling pathway in D-gal-induced aging rats	15
UPLC-QTOF-MS with a chemical profiling approach for holistic quality evaluation between a material reference of Wen Dan decoction and its commercial preparations	15
Study protocol: Traditional Chinese Medicine (TCM) syndrome differentiation for heart failure patients and its implication for long-term therapeutic outcomes of the Qiliqiangxin capsules	15
Integrated analysis of the chemical-material basis and molecular mechanisms for the classic herbal formula of Lily Bulb and Rehmannia Decoction in alleviating depression	15
An-Gong-Niu-Huang-Wan (AGNHW) regulates cerebral blood flow by improving hypoperfusion, cerebrovascular reactivity and microcirculation disturbances after stroke	14
Two-dimensional cell membrane chromatography guided screening of myocardial protective compounds from Yindan Xinnaotong soft capsule	14
Dual effect of aucubin on promoting VEGFR2 mediated angiogenesis and reducing RANKL-induced bone resorption	14
Pharmacological properties of Polygonatum and its active ingredients for the prevention and treatment of cardiovascular diseases	14
From non-targeted to targeted GC–MS metabolomics strategy for identification of TCM preparations containing natural and artificial musk	14
Identifying traditional Chinese medicine combinations for breast cancer treatment based on transcriptional regulation and chemical structure	14
Aqueous extract of Platycodon grandiflorus attenuates lipopolysaccharide-induced apoptosis and inflammatory cell infiltration in mouse lungs by inhibiting PI3K/Akt signaling	14
The analgesic effects of Yu-Xue-Bi tablet (YXB) on mice with inflammatory pain by regulating LXA4-FPR2-TRPA1 pathway	14
Golden bile powder prevents drunkenness and alcohol-induced liver injury in mice via the gut microbiota and metabolic modulation	14
A strategy for selective screening of dual-target bioactive compounds against hypertrophic scar through inhibiting angiotensin II type 1 receptor while stimulating type 2 receptor from Chinese herbs	14
SKP alleviates the ferroptosis in diabetic kidney disease through suppression of HIF-1α/HO-1 pathway based on network pharmacology analysis and experimental validation	14
Polyphyllin I exerts anti-hepatocellular carcinoma activity by targeting ZBTB16 to activate the PPARγ/RXRα signaling pathway	14
Integrating network pharmacological and experimental models to investigate the therapeutic effects of baicalein in glaucoma	14
Qin-Yu-Qing-Chang decoction reshapes colonic metabolism by activating PPAR-γ signaling to inhibit facultative anaerobes against DSS-induced colitis	14
Therapeutic potential of Lianhua Qingke in airway mucus hypersecretion of acute exacerbation of chronic obstructive pulmonary disease	14
Association of lung-intestinal microecology and lung cancer therapy	14
A clinical experience-based Chinese herbal formula improves ethanol-induced drunken behavior and hepatic steatohepatitis in mice models	13
Panax notoginseng extract and total saponin suppress diet-induced obesity and endoplasmic reticulum stress in epididymal white adipose tissue in mice	13
Personalized bioconversion of Panax notoginseng saponins mediated by gut microbiota between two different diet-pattern healthy subjects	13
Myocardial protective effect and transcriptome profiling of Naoxintong on cardiomyopathy in zebrafish	13
Chaihu-Guizhi-Ganjiang Decoction is more efficacious in treating irritable bowel syndrome than Dicetel according to metabolomics analysis	13
Pharmacokinetic study of the main components of Tanreqing capsules and Tanreqing injections in beagles by liquid chromatography–tandem mass spectrometry	13
Electroacupuncture repairs intestinal barrier by upregulating CB1 through gut microbiota in DSS-induced acute colitis	13
Potential role of tea drinking in preventing hyperuricaemia in rats: biochemical and molecular evidence	13
Weipiling decoction alleviates N-methyl-N-nitro-N′-nitrosoguanidine-induced gastric precancerous lesions via NF-κB signalling pathway inhibition	13
Integrated Chinese and western medicine interventions for atopic dermatitis: a systematic review and meta-analysis	13
Combined with UPLC-Triple-TOF/MS-based plasma lipidomics and molecular pharmacology reveals the mechanisms of schisandrin against Alzheimer’s disease	13
Gegen Qinlian decoction (GQD) inhibits ulcerative colitis by modulating ferroptosis-dependent pathway in mice and organoids	13
Gegen Qinlian Decoction treatment of asymptomatic hyperuricemia by targeting circadian immune function	13
Cyp4a12-mediated retinol metabolism in stellate cells is the antihepatic fibrosis mechanism of the Chinese medicine Fuzheng Huayu recipe	13
Red yeast rice ameliorates non-alcoholic fatty liver disease through inhibiting lipid synthesis and NF-κB/NLRP3 inflammasome-mediated hepatic inflammation in mice	13
Metabolic profiling and pharmacokinetic studies of Baihu-Guizhi decoction in rats by UFLC-Q-TOF–MS/MS and UHPLC-Q-TRAP-MS/MS	13
Therapeutic potential of triptolide in autoimmune diseases and strategies to reduce its toxicity	13
Buyang Huanwu Decoction protects against STZ-induced diabetic nephropathy by inhibiting TGF-β/Smad3 signaling-mediated renal fibrosis and inflammation	13
Integrative network fusion-based multi-omics study for biomarker identification and patient classification of rheumatoid arthritis	13
Jian Yun Qing Hua Decoction inhibits malignant behaviors of gastric carcinoma cells via COL12A1 mediated ferroptosis signal pathway	13
Natural L-type calcium channels antagonists from Chinese medicine	12
Dipeptide PA3264 derived from rare and endangered Squama Manis is a novel bioactive peptide for the treatment of triple-negative breast cancer	12
Correction: Cucurbitacin B inhibits TGF-β1-induced epithelial–mesenchymal transition (EMT) in NSCLC through regulating ROS and PI3K/Akt/mTOR pathways	12
An integrated approach for studying exposure, metabolism, and disposition of traditional Chinese medicine using PATBS and MDRB tools: a case study of semen Armeniacae Amarum	12
Deciphering the benefits and intensity levels of primary metabolites from Allium macrostemon Bunge and Allium chinense G. Don	12

Rhei Undulati Rhizoma attenuates memory decline and reduces amyloid-β induced neuritic dystrophy in 5xFAD mouse	12
Exploring the immunometabolic potential of Danggui Buxue Decoction for the treatment of IBD-related colorectal cancer	12
Shen-Bai-Jie-Du decoction suppresses the progression of colorectal adenoma to carcinoma through regulating gut microbiota and short-chain fatty acids	12
Gastrodin attenuates diabetic cardiomyopathy characterized by myocardial fibrosis by inhibiting the KLK8-PAR1 signaling axis	12
Potential mechanism of Taohong Siwu Decoction in uterine fibroid treatment based on integrated strategy of network pharmacology and experimental verification	12
Correction: Neuroprotective effects of Shende’an tablet in the Parkinson’s disease model	12
Systematic investigation of the material basis, effectiveness and safety of Thesium chinense Turcz. and its preparation Bairui Granules against lung inflammation	12
The role of Chinese herbal medicine in the regulation of oxidative stress in treating hypertension: from therapeutics to mechanisms	12
Machine learning-assisted rapid determination for traditional Chinese Medicine Constitution	12