Chinese Medicine

Article	Citations
What we already know about rhubarb: a comprehensive review	91
Tea and tea drinking: China’s outstanding contributions to the mankind	82
Reflections on treatment of COVID-19 with traditional Chinese medicine	59
The potential insights of Traditional Chinese Medicine on treatment of COVID-19	58
Applications, phytochemistry, pharmacological effects, pharmacokinetics, toxicity of Scutellaria baicalensis Georgi. and its probably potential therapeutic effects on COVID-19: a review	57
Quality standard of traditional Chinese medicines: comparison between European Pharmacopoeia and Chinese Pharmacopoeia and recent advances	52
Network pharmacology based research into the effect and mechanism of Yinchenhao Decoction against Cholangiocarcinoma	51
Flavonoids on diabetic nephropathy: advances and therapeutic opportunities	51
Traditional application and modern pharmacological research of Eucommia ulmoides Oliv.	51
Mechanism of Dayuanyin in the treatment of coronavirus disease 2019 based on network pharmacology and molecular docking	45
Honokiol alleviates LPS-induced acute lung injury by inhibiting NLRP3 inflammasome-mediated pyroptosis via Nrf2 activation in vitro and in vivo	44
Propolis: An update on its chemistry and pharmacological applications	41
Pharmacological activities and mechanisms of action of Pogostemon cablin Benth: a review	41
Salidroside attenuates neuronal ferroptosis by activating the Nrf2/HO1 signaling pathway in Aβ1-42-induced Alzheimer’s disease mice and glutamate-injured HT22 cells	41
Traditional Chinese medicine for anti-Alzheimer’s disease: berberine and evodiamine from Evodia rutaecarpa	39
Traditional Chinese Medicine for adjuvant treatment of breast cancer: Taohong Siwu Decoction	38
The mechanism of electroacupuncture for depression on basic research: a systematic review	37
Flavonoids from Aurantii Fructus Immaturus and Aurantii Fructus: promising phytomedicines for the treatment of liver diseases	36
Plant metabolomics: a new strategy and tool for quality evaluation of Chinese medicinal materials	36
Anemoside B4 ameliorates TNBS-induced colitis through S100A9/MAPK/NF-κB signaling pathway	34
Advances in the study of emodin: an update on pharmacological properties and mechanistic basis	34
Anti-inflammatory properties of uvaol on DSS-induced colitis and LPS-stimulated macrophages	34
Neurobiological effects of gallic acid: current perspectives	32
Artesunate: could be an alternative drug to chloroquine in COVID-19 treatment?	31
Traditional Chinese Medicine in nonalcoholic fatty liver disease: molecular insights and therapeutic perspectives	31

Natural drug sources for respiratory diseases from Fritillaria: chemical and biological analyses	30
Quinic acid: a potential antibiofilm agent against clinical resistant Pseudomonas aeruginosa	30
Insight into norcantharidin, a small-molecule synthetic compound with potential multi-target anticancer activities	30
Zoology, chemical composition, pharmacology, quality control and future perspective of Musk (Moschus): a review	28
The toxicology and detoxification of Aconitum: traditional and modern views	28
Acupuncture for cancer pain: an evidence-based clinical practice guideline	27
The important herbal pair for the treatment of COVID-19 and its possible mechanisms	27
Plant super-barcode: a case study on genome-based identification for closely related species of Fritillaria	26
Therapeutic potential of triptolide in autoimmune diseases and strategies to reduce its toxicity	26
Efficacy and mechanisms of traditional Chinese medicine for COVID-19: a systematic review	26
Microwave technology: a novel approach to the transformation of natural metabolites	25
Recent advances of novel technologies for quality consistency assessment of natural herbal medicines and preparations	25
Chaihu-Shugan-San (Shihosogansan) alleviates restraint stress-generated anxiety and depression in mice by regulating NF-κB-mediated BDNF expression through the modulation of gut microbiota	25
Cucurbitacin B inhibits TGF-β1-induced epithelial–mesenchymal transition (EMT) in NSCLC through regulating ROS and PI3K/Akt/mTOR pathways	25
Niosomes of active Fumaria officinalis phytochemicals: antidiabetic, antineuropathic, anti-inflammatory, and possible mechanisms of action	25
The drug likeness analysis of anti-inflammatory clerodane diterpenoids	24
From natural dye to herbal medicine: a systematic review of chemical constituents, pharmacological effects and clinical applications of indigo naturalis	24
Research progress on the ethanol precipitation process of traditional Chinese medicine	24
Current status of traditional Chinese medicine for the treatment of COVID-19 in China	24
Oral colon-targeting core–shell microparticles loading curcumin for enhanced ulcerative colitis alleviating efficacy	23
Combination of pseudoephedrine and emodin ameliorates LPS-induced acute lung injury by regulating macrophage M1/M2 polarization through the VIP/cAMP/PKA pathway	23
Potential mechanism prediction of Cold-Damp Plague Formula against COVID-19 via network pharmacology analysis and molecular docking	23
Tanshinone I exerts cardiovascular protective effects in vivo and in vitro through inhibiting necroptosis via Akt/Nrf2 signaling pathway	23
Mechanism of drug-induced liver injury and hepatoprotective effects of natural drugs	23
Neurogenesis-dependent antidepressant-like activity of Hericium erinaceus in an animal model of depression	23
Intake of flavonoids from Astragalus membranaceus ameliorated brain impairment in diabetic mice via modulating brain-gut axis	22
Traditional Chinese herbal medicine-potential therapeutic application for the treatment of COVID-19	22
DNA barcoding: an efficient technology to authenticate plant species of traditional Chinese medicine and recent advances	22
Body fluids may contribute to human-to-human transmission of severe acute respiratory syndrome coronavirus 2: evidence and practical experience	22
Acupuncture methods for allergic rhinitis: a systematic review and bayesian meta-analysis of randomized controlled trials	21
Anti-platelet aggregation of Panax notoginseng triol saponins by regulating GP1BA for ischemic stroke therapy	21
Huanglian Jiedu Decoction ameliorates DSS-induced colitis in mice via the JAK2/STAT3 signalling pathway	21
The involvement of human organic anion transporting polypeptides (OATPs) in drug-herb/food interactions	21
The role of macrophage polarization and associated mechanisms in regulating the anti-inflammatory action of acupuncture: a literature review and perspectives	21
Therapeutic material basis and underling mechanisms of Shaoyao Decoction-exerted alleviation effects of colitis based on GPX4-regulated ferroptosis in epithelial cells	21
Chinese herbal medicines in the treatment of ulcerative colitis: a review	21
Anti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo	20
The scientific elucidation of daodi medicinal materials	20
Honokiol attenuates lipotoxicity in hepatocytes via activating SIRT3-AMPK mediated lipophagy	20
The emerging possibility of the use of geniposide in the treatment of cerebral diseases: a review	20
Catechins from oolong tea improve uterine defects by inhibiting STAT3 signaling in polycystic ovary syndrome mice	20
A network pharmacology approach to reveal the pharmacological targets and biological mechanism of compound kushen injection for treating pancreatic cancer based on WGCNA and in vitro experiment valida	20
Composition and function of rhizosphere microbiome of Panax notoginseng with discrepant yields	20
Pharmacological activities and molecular mechanisms of Pulsatilla saponins	20
Transcription factor EB agonists from natural products for treating human diseases with impaired autophagy-lysosome pathway	19
CRISPR-Cas gene editing technology and its application prospect in medicinal plants	19
Integrated analysis of the chemical-material basis and molecular mechanisms for the classic herbal formula of Lily Bulb and Rehmannia Decoction in alleviating depression	19
Applying regulatory science in traditional chinese medicines for improving public safety and facilitating innovation in China: a scoping review and regulatory implications	19
Shikonin promotes ubiquitination and degradation of cIAP1/2-mediated apoptosis and necrosis in triple negative breast cancer cells	19
Efficacy of acupuncture in the prevention and treatment of chemotherapy-induced nausea and vomiting in patients with advanced cancer: a multi-center, single-blind, randomized, sham-controlled clinical	18

Systemic elucidation on the potential bioactive compounds and hypoglycemic mechanism of Polygonum multiflorum based on network pharmacology	18
Effects of ginsenosides on bone remodelling for novel drug applications: a review	18
Comparison of volatile compounds in different parts of fresh Amomum villosum Lour. from different geographical areas using cryogenic grinding combined HS–SPME–GC–MS	18
Characterization of thrombin/factor Xa inhibitors in Rhizoma Chuanxiong through UPLC-MS-based multivariate statistical analysis	18
Efficacy and safety of traditional Chinese medicines for non-alcoholic fatty liver disease: a systematic literature review of randomized controlled trials	18
Exploring biological basis of Syndrome differentiation in coronary heart disease patients with two distinct Syndromes by integrated multi-omics and network pharmacology strategy	18
Two methoxy derivatives of resveratrol, 3,3′,4,5′-tetramethoxy-trans-stilbene and 3,4′,5-trimethoxy-trans-stilbene, suppress lipopolysaccharide-induced inflammation through inactivation of MAPK and NF	17
Recent advance in treatment of osteoarthritis by bioactive components from herbal medicine	17
Effects of ginsenoside Rb1 on second-degree burn wound healing and FGF-2/PDGF-BB/PDGFR-β pathway modulation	17
Psoralea corylifolia L.: a comprehensive review of its botany, traditional uses, phytochemistry, pharmacology, toxicology, quality control and pharmacokinetics	17
Saikosaponin D exerts antidepressant effect by regulating Homer1-mGluR5 and mTOR signaling in a rat model of chronic unpredictable mild stress	17
Determination of the protective effects of Hua‐Zhuo‐Jie‐Du in chronic atrophic gastritis by regulating intestinal microbiota and metabolites: combination of liquid chromatograph mass spectrometer meta	17
Phytochemicals targeting Toll-like receptors 4 (TLR4) in inflammatory bowel disease	17
Anemoside B4 protects against Klebsiella pneumoniae- and influenza virus FM1-induced pneumonia via the TLR4/Myd88 signaling pathway in mice	17
Shengmai Yin formula modulates the gut microbiota of spleen-deficiency rats	17
The three syndromes and six Chinese patent medicine study during the recovery phase of COVID-19	16
Transcriptome analyses revealed the ultraviolet B irradiation and phytohormone gibberellins coordinately promoted the accumulation of artemisinin in Artemisia annua L.	16
Modulation of steroidogenesis by Actaea racemosa and vitamin C combination, in letrozole induced polycystic ovarian syndrome rat model: promising activity without the risk of hepatic adverse effect	16
Geniposide suppresses NLRP3 inflammasome-mediated pyroptosis via the AMPK signaling pathway to mitigate myocardial ischemia/reperfusion injury	16
Research of insomnia on traditional Chinese medicine diagnosis and treatment based on machine learning	16
In vitro anti‐bacterial activity and network pharmacology analysis of Sanguisorba officinalis L. against Helicobacter pylori infection	16
Protective mechanism of rhubarb anthraquinone glycosides in rats with cerebral ischaemia–reperfusion injury: interactions between medicine and intestinal flora	15
A network pharmacology-based approach to explore the active ingredients and molecular mechanism of Lei-gong-gen formula granule on a spontaneously hypertensive rat model	15
Si-Wu-Tang ameliorates fibrotic liver injury via modulating intestinal microbiota and bile acid homeostasis	15
Ginsenoside Rg1 alleviates repeated alcohol exposure-induced psychomotor and cognitive deficits	15
Honeysuckle-derived microRNA2911 inhibits tumor growth by targeting TGF-β1	15
Repurposing a clinically approved prescription Colquhounia root tablet to treat diabetic kidney disease via suppressing PI3K/AKT/NF-kB activation	15
Fermentation of Danggui Buxue Tang, an ancient Chinese herbal mixture, together with Lactobacillus plantarum enhances the anti-diabetic functions of herbal product	15
Strategies for molecular authentication of herbal products: from experimental design to data analysis	15
Medicinal plants utilized in the management of epilepsy in Ethiopia: ethnobotany, pharmacology and phytochemistry	15
Quality assessment and Q-markers discovery of Tongsaimai tablet by integrating serum pharmacochemistry and network pharmacology for anti-atherosclerosis benefit	14
New bakuchiol dimers from Psoraleae Fructus and their inhibitory activities on nitric oxide production	14
Inflammatory bowel disease: an overview of Chinese herbal medicine formula-based treatment	14
A review of Chinese medicine for the treatment of psoriasis: principles, methods and analysis	14
Research progress on quality assurance of genuine Chinese medicinal in Sichuan	14
Trilobatin ameliorates insulin resistance through IRS-AKT-GLUT4 signaling pathway in C2C12 myotubes and ob/ob mice	14
Beneficial effect of Indigo Naturalis on acute lung injury induced by influenza A virus	14
Isoflavones daidzin and daidzein inhibit lipopolysaccharide-induced inflammation in RAW264.7 macrophages	14
The protective effects of liguzinediol on congestive heart failure induced by myocardial infarction and its relative mechanism	14
Suan-Zao-Ren Decoction ameliorates synaptic plasticity through inhibition of the Aβ deposition and JAK2/STAT3 signaling pathway in AD model of APP/PS1 transgenic mice	14
Traditional chinese medicine syndromes classification associates with tumor cell and microenvironment heterogeneity in colorectal cancer: a single cell RNA sequencing analysis	13
Panax ginseng C. A. Meyer as a potential therapeutic agent for organ fibrosis disease	13
Ginsenoside Rh2 represses autophagy to promote cervical cancer cell apoptosis during starvation	13
Red yeast rice ameliorates non-alcoholic fatty liver disease through inhibiting lipid synthesis and NF-κB/NLRP3 inflammasome-mediated hepatic inflammation in mice	13
Roles of reactive oxygen species, mitochondrial membrane potential, and p53 in evodiamine-induced apoptosis and G2/M arrest of human anaplastic thyroid carcinoma cells	13
Nitidine chloride induces caspase 3/GSDME-dependent pyroptosis by inhibting PI3K/Akt pathway in lung cancer	13
Therapeutic roles of natural remedies in combating hereditary ataxia: A systematic review	13
Bidirect effects from cisplatin combine with rosmarinic acid (RA) or hot water extracts of Glechoma hederacea (HWG) on renal cancer cells	13
Protective effects of Ginkgo Biloba Dropping Pills against liver ischemia/reperfusion injury in mice	13
Effects of Chinese medicine for COVID-19 rehabilitation: a multicenter observational study	13
Effects of alkaloids on peripheral neuropathic pain: a review	13
Towards a better understanding of Fagopyrum dibotrys: a systematic review	13
Echinacoside exhibits antidepressant-like effects through AMPAR–Akt/ERK–mTOR pathway stimulation and BDNF expression in mice	13
Current strategies against COVID-19	13
Corydalis saxicola Bunting total alkaloids attenuate paclitaxel-induced peripheral neuropathy through PKCε/p38 MAPK/TRPV1 signaling pathway	12
Ganoderma spore powder contains little triterpenoids	12
Global trends and prospects about inflammasomes in stroke: a bibliometric analysis	12
Traditional Chinese medicine promotes bone regeneration in bone tissue engineering	12
A review on the applications of Traditional Chinese medicine polysaccharides in drug delivery systems	12
Metabolomics coupled with integrated approaches reveal the therapeutic effects of higenamine combined with [6]-gingerol on doxorubicin-induced chronic heart failure in rats	12
P2Y12 receptor as a new target for electroacupuncture relieving comorbidity of visceral pain and depression of inflammatory bowel disease	12
A correlational study of Weifuchun and its clinical effect on intestinal flora in precancerous lesions of gastric cancer	12
Medicinal plants used in managing diseases of the respiratory system among the Luo community: an appraisal of Kisumu East Sub-County, Kenya	12
Herbal formula Huangqi Guizhi Wuwu decoction attenuates paclitaxel-related neurotoxicity via inhibition of inflammation and oxidative stress	12
Integrated assessment of medicinal rhubarb by combination of delayed luminescence and HPLC fingerprint with emphasized on bioactivities based quality control	12
Improvement of intestinal flora: accompany with the antihypertensive effect of electroacupuncture on stage 1 hypertension	12
Medicinal and edible plants in the treatment of dyslipidemia: advances and prospects	12
Persimmon leaf extract alleviates chronic social defeat stress-induced depressive-like behaviors by preventing dendritic spine loss via inhibition of serotonin reuptake in mice	12
Buyang Huanwu Decoction protects against STZ-induced diabetic nephropathy by inhibiting TGF-β/Smad3 signaling-mediated renal fibrosis and inflammation	12
Traditional herbal formula Wu-Mei-Wan alleviates TNBS-induced colitis in mice by inhibiting necroptosis through increasing RIPK3 O-GlcNAcylation	12
Integrating metabolomic data with machine learning approach for discovery of Q-markers from Jinqi Jiangtang preparation against type 2 diabetes	12
Comparison of the chemical constituents and anti-Alzheimer’s disease effects of Uncaria rhynchophylla and Uncaria tomentosa	12
The effect of total glucoside of paeony on gut microbiota in NOD mice with Sjögren’s syndrome based on high-throughput sequencing of 16SrRNA gene	12
Traditional Chinese medicine Lingguizhugan decoction ameliorate HFD-induced hepatic-lipid deposition in mice by inhibiting STING-mediated inflammation in macrophages	11
Dissecting the mechanism of Yuzhi Zhixue granule on ovulatory dysfunctional uterine bleeding by network pharmacology and molecular docking	11
Frontier progress of the combination of modern medicine and traditional Chinese medicine in the treatment of hepatocellular carcinoma	11
Cryptotanshinone attenuates the stemness of non-small cell lung cancer cells via promoting TAZ translocation from nuclear to cytoplasm	11
Toosendanin, a late-stage autophagy inhibitor, sensitizes triple-negative breast cancer to irinotecan chemotherapy	11
Eryngium caeruleum: an update on ethnobotany, phytochemistry and biomedical applications	11
Gut microbiota: a potential target for traditional Chinese medicine intervention in coronary heart disease	11

A novel multidimensional strategy to evaluate Belamcanda chinensis (L) DC and Iris tectorum Maxim based on plant metabolomics, digital reference standard analyzer and biological activities evaluation	11
Alpinetin promotes hair regeneration via activating hair follicle stem cells	11
Effects of acupuncture at acupoints with lower versus higher pain threshold for knee osteoarthritis: a multicenter randomized controlled trial	11
Mineral medicine: from traditional drugs to multifunctional delivery systems	11
Astragalus membranaceus (Huangqi) and Rhizoma curcumae (Ezhu) decoction suppresses colorectal cancer via downregulation of Wnt5/β-Catenin signal	11
Identification of anti-inflammatory compounds from Zhongjing formulae by knowledge mining and high-content screening in a zebrafish model of inflammatory bowel diseases	11
Direct and indirect therapeutic effect of traditional Chinese medicine as an add-on for non-proliferative diabetic retinopathy: a systematic review and meta-analysis	11
Scutellarin ameliorates neonatal hypoxic-ischemic encephalopathy associated with GAP43-dependent signaling pathway	11
Shikonin attenuates rheumatoid arthritis by targeting SOCS1/JAK/STAT signaling pathway of fibroblast like synoviocytes	11