Epigenomics

Papers
(The median citation count of Epigenomics is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)
ArticleCitations
DNMT3L Interacts with Piwi and Modulates the Expression of piRNAs in Transgenic Drosophila60
Decoding the Year of 2023: Welcome to the 16th Volume of Epigenomics53
Association between epigenetic aging and atrioventricular block: a two-sample Mendelian randomization study53
Epigenetic Signature of Exposure to Maternal Trypanosoma Cruzi Infection in Cord Blood Cells from Uninfected Newborns36
Unlocking the Epigenetic Symphony: Histone Acetylation’s Impact on Neurobehavioral Change in Neurodegenerative Disorders33
The epigenetic roles of pirfenidone - implication in liver disease management31
Altered epigenetic landscape as infectious disease diagnostics28
Precision Epigenetics Provides a Scalable Pathway for Improving Coronary Heart Disease Care Globally27
Epigenetic alterations in prostate cancer: the role of chromatin remodeling26
Cumulative psychosocial factors and epigenetic age acceleration in the Hispanic Community Health Study/Study of Latinos24
The role of long non-coding RNA in the pathogenesis of aneurysms23
Epigenetics in evolution and adaptation to environmental challenges: pathways for disease prevention and treatment23
Exosome-transmitted microRNA-323a-3p participated in the occurrence of Hirschsprung’s disease20
From allergens to epigenetics: how histone acetylation shapes immune gene expression in allergic diseases20
Association between Alcohol Consumption and DNA Methylation in Blood: A Systematic Review of Observational Studies20
Epigenetics and Cutaneous Neoplasms: From Mechanism to Therapy19
Epigenome-Wide Studies of Antipsychotics: A Systematic Review and Pathway Meta-Analysis19
Comparison of Methylation Episignatures in KMT2B - and KMT2D -Related Human Disorders19
The Impact and Mechanism of TET3 Overexpression on the Progression of Hepatic Fibrosis19
Epigenetic rejuvenation: a journey backwards towards an epigenomic ground state18
Targeting Tudor domains in leukemia: epigenetic insights for drug development18
Advancing epigenetic signatures as functional biomarkers in rare diseases17
The hMeDIP-Seq Identified  INPP4A as a Novel Biomarker for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps16
Alteration of the N 6 -Methyladenosine Epitranscriptomic Profile in Synthetic Phthalate-Treated Human Induced Pluripotent Stem Cell-Derived Endothelial Cells16
The Study of HMOX1 DNA Methylation and Gene Expression and the Diagnostic Potential of miR-153-3p in Preeclampsia16
Age-Related Changes in Sperm DNA Methylation and their Forensic and Clinical Implications16
Coregulatory effects of multiple histone modifications in key ferroptosis-related genes for lung adenocarcinoma15
SET Protein as an Epigenetics Target15
Decoding Mitochondrial–Nuclear (epi)genome Interactions: The Emerging Role of ncRNAs15
The eighth annual US DOHAD meeting: promising approaches in epigenetics research of early life exposures14
Phytochemicals in Cervical Cancer: An Epigenetic Overview14
Blocking RPA-based methods for the determination of CpG methylation status and detection of gene mutations14
High methylation of the same promoter of lncRNA ZNF582-AS1 / ZNF582 promotes malignant progression of esophageal cancer13
Human RNA-Directed DNA Methylation Methylates High-Mobility Group Box 1 Protein-Produced DNA Gaps13
Combined therapy targeting AR and EZH2 curbs castration-resistant prostate cancer enhancing anti-tumor T-cell response13
Matched Analysis of Detailed Peripheral Blood and Tumor Immune Microenvironment Profiles in Bladder Cancer13
EWAS in COPD by biomass-burning smoke exposure identifies low levels of endothelin-1 by hypermethylation of EDN113
Circular RNAs as multifaceted molecular regulators of vital activity and potential biomarkers of aging13
DNA methylation age acceleration mediates the relationship between systemic inflammation and cognitive impairment13
Blood-based DNA methylation markers for autism spectrum disorder identification using machine learning12
ncRNAs as Biomarkers and Therapeutic Targets for Bronchiectasis12
POU2F2-mediated Upregulation of lncRNA PTPRG-AS1 Inhibits Ferroptosis in Breast Cancer Via miR-376c-3p/SLC7A11 Axis12
Insights to aging prediction with AI based epigenetic clocks12
Three generations of epigenetic clocks in mediating the adverse effect of smoking on metabolic health12
Integrated epigenomic exposure signature discovery11
Beadchip Technology to Detect DNA Methylation in Mouse Faithfully Recapitulates Whole-Genome Bisulfite Sequencing11
Dissecting the Nuances of Cancer Epigenomics in Liquid Biopsy11
Role Of Epigenetic Drugs In Sensitizing Cancers To Anticancer Therapies: Emerging Trends And Clinical Advancements10
microRNAs and their Therapeutic Strategy in Phase I and Phase II Clinical Trials10
Exploring the Molecular Targets for Type 2 Diabetes-Induced Alzheimer’s Disease Through Bioinformatics Analysis10
The epigenetics of frailty10
Epigenetics and suicidal behavior in adolescents: a critical review10
LINC01232 promotes ARNTL2 transcriptional activation and inhibits ferroptosis of CRC cells through p300/H3K27ac9
m 6 A Modification and its Role in Neural Development and Neurological Diseases9
Epigenetic Memory in Breast Cancer: Electrochemical Biosensor-Based Tracing of Histone H3 Acetylation Inheritance9
Exploring Perinatal Biopsychosocial Factors and Epigenetic Age in 1-Year-Old Offspring9
Combined replacement of lnc-MEG3 and miR-155 elicit tumor suppression in multiple myeloma9
MiR-4732-3p Prevents Lung Cancer Progression via Inhibition of the TBX15/TNFSF11 Axis9
Transcription Factors: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma9
Emerging roles of RNA modifications in normal development and congenital craniofacial malformations9
Associations Between Grimage Acceleration and Pulmonary Function in the Coronary Artery Risk Development in Young Adults (CARDIA) Study9
Computational-based integrative methylome-transcriptome analysis reveals widespread enhancer hypomethylation in esophageal carcinoma8
DNA methylation profile to aid in the diagnosis of pancreatic ductal adenocarcinoma and its role in disease progression8
Constructed Competitive Endogenous RNA Network and Patterns of Immune Infiltration Revealing the Prognostic Signature for Cervical Cancer8
Mom genes and dad genes: genomic imprinting in the regulation of social behaviors8
METTL3 promotes Non-Small-Cell Lung Cancer Growth and Metastasis by Inhibiting FDX1 Through Copper Death-Associated Pri-miR-21-5p Maturation8
The epigenetic potential of vitamin K2 in brain health8
The Role of N 6 -Methyladenosine RNA Modification in Platinum Resistance8
A father’s legacy: the sperm epigenome, preimplantation development, and paternal environment8
Epigenome-Wide Association Study of Serum Folate in Maternal Peripheral Blood Leukocytes8
Mitochondrial D-loop Methylation Levels Inversely Correlate with Disease Duration in Amyotrophic Lateral Sclerosis8
Integrative analysis of a novel 5 methylated snoRNA genes prognostic signature in patients with glioma8
Mitochondrial DNA copy number reduction via in vitro TFAM knockout remodels the nuclear epigenome and transcriptome7
Dulaglutide as a Demethylating Agent to Improve the Outcome of Breast Cancer7
Paternal preconception exercise and sperm epigenetic mechanisms: a systematic review on offspring health7
Epigenetics: the missing link between environmental exposures and Parkinson's disease?7
Dna Methylation as a Powerful Tool to Investigate the Biology and Pathology of Aging7
The Epigenetic Landscape: How Environmental Cues Shape Gene Expression7
Cell-free DNA methylation patterns in aging and their association with inflamm-aging7
DNA methylation associations with cognitive function in early-stage hormone receptor-positive breast cancer patients7
RASSF1A Promotes ATM Signaling and RASSF1A Methylation is a Synthetic Lethal Marker for ATR Inhibitors7
EpiSmokEr2: a robust epigenetic classifier for smoking status inference using Illumina EPIC methylation data7
PTEN Promoter Methylation And Expression In Endometrial Cancer Tissues7
Epigenetics of cerebrovascular diseases: an update review of clinical studies6
Epigenetic Disruption of Histone Deacetylase-2 Accelerated Apoptotic Signaling and Retarded Malignancy in Gastric Cells6
Association between imprinting disorders and assisted reproductive technologies6
Epigenetic landscape of intestinal cell line HT29 cocultured with Lacticaseibacillus6
Epigenetic Regulation of Vitamin D Deficiency6
Breaking the epigenetic code with MARCS: the Modification Atlas of Regulation by Chromatin States6
Development and validation of a novel cell type estimation method for targeted bisulfite sequencing data6
Placental expression and methylation of angiogenic factors in assisted reproductive technology pregnancies from India6
Targeting TET enzymes in ovarian cancer: epigenetic regulation, chemoresistance, and therapeutic opportunities6
Psychiatry and sensation: the epigenetic links6
Bridging the gap: R-loop mediated genomic instability and its implications in neurological diseases6
Non-coding RNAs regulation in breast cancer pathogenesis6
A narrative review of epigenetic marker in H3K27ac and its emerging potential as a therapeutic target in cancer6
Clinical Uses of Epigenetics in Cardiology and Cardiothoracic Surgery: An Update6
MDM2 and DNMT1 inhibitors induce neuroblastoma cell death through p53-dependent and independent pathways6
DNA methylation-based health predictors: advances, applications, and perspectives6
The regulation of microRNAs on chemoresistance in triple-negative breast cancer: a recent update6
Dna Methylation Episignatures are Sensitive and Specific Biomarkers for Detection of Patients with Kat6A / Kat6B Variants6
cfDNA Methylation in Liquid Biopsies as Potential Testicular Seminoma Biomarker6
Dysregulation of epigenetic modifications in inborn errors of immunity6
The Epigenetics Orchestra of Notch Signaling: A Symphony for Cancer Therapy6
Accurate interpretation of inosines in RNAs: recognized as G is more than basepairing with C6
Transcriptome Profiling and ceRNA Network of Small Extracellular Vesicles from Resting and Degranulated Mast Cells6
The Role of H3K9 Acetylation and Gene Expression in Different Brain Regions of Alzheimer’s Disease Patients6
Methylation changes of gallbladder DNA during the formation of gallstones6
Impact of prematurity on LINE-1 promoter methylation5
PEMT Variants are Associated with Nonsyndromic Cleft Lip with or without Cleft Palate in Chile5
SIX4 , a Potential Therapeutic Target for Estrogen Receptor-Positive Breast Cancer Patients, is Associated with low Promoter Methylation Level5
Performance Comparisons of Methylation and Structural Variants From Low-Input Whole-Genome Methylation Sequencing5
Combining EZH2 inhibitors with other therapies for solid tumors: more choices for better effects5
Recent advances in methodologies of epigenomics5
The mystique of epigenetic regulation: the remarkable case of a human noncoding RNA, nc8865
Epigenomic mechanisms of dietary prescriptions for obesity therapy5
tRNA-derived RNAs in human milk extracellular vesicles and associations with breastfeeding variables and maternal diet5
Role of epigenetic markers in cardiovascular disease following hypertensive disorders of pregnancy5
Environmental aging: through the prism of DNA methylation5
DNA Methylation as a Window into Female Reproductive Aging5
ALKBH5-mediated m6A demethylation of TXNDC5 drives malignant progression in gastric cancer5
Epigenomic Impacts of Meditative Practices5
Super-enhancers: drivers of cells’ identities and cells’ debacles5
Methylation changes of liver DNA during the formation of gallstones5
Epigenetic landscape of Leishmania-host interactions5
Current trends in clinical trials and the development of small molecule epigenetic inhibitors as cancer therapeutics5
Deciphering KDM8 dysregulation and CpG methylation in hepatocellular carcinoma using multi-omics and machine learning5
Assessing the epigenetic consequences of ART in male infertility: what risks to embryo and offspring health?5
Reduction in ELOVL2 methylation following curative surgery in lung cancer patients: an observational study4
Will methylation assays be part of a full molecular strategy to improve clinical management of cervical neoplasia?4
Predictive power of epigenetic age – opportunities and cautions4
The third symposium on treatment-induced neuroendocrine prostate cancer: insights and future directions4
Epigenetic mechanisms in maternal-fetal crosstalk: inter- and trans-generational inheritance4
Accelerated epigenetic aging and shorter DNA methylation-based telomere length in sarcopenic obesity: an exploratory pilot study4
DNA methylation of miR-181a-5p mediated by DNMT3b drives renal interstitial fibrosis developed from acute kidney injury4
The triple code model for advancing research in rare and undiagnosed diseases beyond the base pairs4
Inter-individual differentially methylated region-targeted EWAS reveals epigenetic signatures of early childhood adversity4
lncRNA GMDS-AS1 Restrains Lung Adenocarcinoma Progression Via Recruiting TAF15 Protein to Stabilize SIRT1 mRNA4
Statement of Retraction: KDM6B Histone Demethylase is an Epigenetic Regulator of Estrogen Receptor β Expression in Human Pleural Mesothelioma4
Exploring mRNA Translation Strategies for Hypoxia Adaptation Across Distantly Related Metazoans4
Epigenetic Association Study Uncovered H3K27 Acetylation Enhancers and Dysregulated Genes in High-Fat-Diet-Induced Nonalcoholic Fatty Liver Disease in Rats4
Analysis on methylation and expression of PSMB8 and its correlation with immunity and immunotherapy in lung adenocarcinoma4
Defining familial longevity and developing a familial longevity score for unbiased epigenetic studies in a birth cohort4
Mitochondrial D-loop region methylation differentiates Parkinson’s disease from atypical parkinsonism and Parkinson’s disease dementia4
Techniques to detect physical interactions between genomic regions4
DNA methylation-predicted protein differences between Yakutian and Central Russian populations4
Hypermethylation Of CTDSPL2 Prior To Necrotizing Enterocolitis Onset4
Community Engagement in Epigenomic and Neurocognitive Research on Post-Traumatic Stress Disorder in Rwandans Exposed to the 1994 Genocide against the Tutsi: Lessons Learned4
Neural Tube Defects and Epigenetics: Role of Histone Post-Translational Histone Modifications4
New insights into the dynamics of m6A epitranscriptome: hybrid-seq identifies novel mRNAs of the m6A writers METTL3/144
The emerging role of multiomics in aging research4
Mediators of maternal intergenerational epigenetic inheritance in mammals4
miR-17-5p: bridging the gap between disease mechanisms and therapeutic innovations4
Differential methylation patterns from clusters associated with glucose metabolism: evidence from a Shanghai twin study4
Role of Epigenetics in Innate Lymphoid Cells4
Methylation aberrations and genomic instability synergistically drive the evolution of intrahepatic cholangiocarcinoma4
Cancer epigenetic therapy: recent advances, challenges, and emerging opportunities4
There’s More to it: Uncovering Genomewide DNA Methylation Heterogeneity4
The novel ferroptosis-inducing molecule can inhibit the progression of BC by regulating the ubiquitination of UHRF13
Pyroptosis-Related Lncrna Prognostic Signatures for Cutaneous Melanoma and Tumor Microenvironment Status3
High level of KMT5C is associated to better prognosis and its knockdown increases proliferation in head and neck cancer3
Genome-wide Methylation Analysis of Post-Mortem Cerebellum Samples Supports the Role of Peroxisomes in Autism Spectrum Disorder3
S-adenosylmethionine as an epigenetic treatment of depression in adults with childhood trauma3
Correction3
Evaluating the Clinical Performance of SDC2/NDRG4 Methylation for Colorectal Cancer Detection3
Epigenetic identification of LTBP4 as a putative tumor suppressor in breast cancer3
Beyond the genome: intergenerational inheritance through epigenetics and other pathways3
Secretion of Acetylated Amino Acids by Drug-Induced Cancer Cells: Perspectives on Metabolic-Epigenetic Alterations3
HTR2A DNA methylation as a diagnostic biomarker for rheumatoid arthritis: a validation study using targeted sequencing3
Regulatory roles of transposable elements on autism molecular neuropathology3
The NEAT1/miR-124-3p/CCL2 axis in chronic kidney disease progression: integrated bioinformatics analysis and experimental validation3
Integrated Analysis Revealing the Role Of TET3-Mediated MUC13 Promoter Hypomethylation in Hepatocellular Carcinogenesis3
Complex Cross-Talk between EZH2 and Mirnas Confers Hallmark Characteristics and Shapes the Tumor Microenvironment3
Epigenetics and suicide: investigating altered H3K14ac unveiled differential expression in ADORA2A , B4GALT2  and MMP143
Genome-Wide Methylation Analyses of Human Sperm Unravel Novel Differentially Methylated Regions in Asthenozoospermia3
Clinically Informative Micrornas for SARS-CoV-2 Infection3
EZH2 inhibition enhances the activity of Carboplatin in aggressive-variant prostate cancer cell lines3
E2F1-driven cholesterol synthesis via the SND1/ACLY axis potentiates malignant progression in prostate cancer3
DNA methylation biomarkers for the diagnosis and treatment management of breast cancer: where are we now?3
Cellular and epigenetic perspective of protein stability and its implications in the biological system3
LncRNA H19 Promotes Tumor Angiogenesis in Smokers by Targeting Anti-Angiogenic MiRNAs3
Identification of Three lncRNA-Related Prognostic Signatures in Gastric Cancer by Integrated Multi-Omics Analysis3
Circulating non-coding RNAs as a tool for liquid biopsy in solid tumors3
m 6 A-Mediated Upregulation of lncRNA RMRP Boosts the Progression of Bladder Cancer Via Epigenetically Suppressing SCAR3
Generations of epigenetic clocks and their links to socioeconomic status in the Health and Retirement Study3
Calculating Detection Limits and Uncertainty of Reference-Based Deconvolution of Whole-Blood DNA Methylation Data3
Hsa_Circ_0092339 Acts as a Molecular Sponge in Castration-Resistant Prostate Cancer via the Hsa-Mir-940/ C-MYC Axis3
Epigenetics in persons living with HIV: trauma, coping, and FKBP5 and SLC6A4 methylation3
lncRNA TUG1 as Potential Novel Biomarker for Prognosis of Cardiovascular Diseases3
An assessment of compositional methods for the analysis of DNA methylation-based deconvolution estimates3
Methylation levels in keratinocyte basal cells reflect donor age and associate with altered cellular proliferation pathways3
Menin: from molecular insights to clinical impact3
The Prognostic Value and Biological Functions of HFM1 in Breast Cancer3
Potential epigenetic markers of clinical diagnostics/therapeutic targets in preeclampsia3
Methylated ZNF582: a therapeutic target in oral cancer3
DNMT3a Promotes Osteoblast Differentiation and Alleviates Osteoporosis Via the PPARγ / SCD1 / GLUT1 3
Multi-omics insights into the pathogenesis of diabetic cardiomyopathy: epigenetic and metabolic profiles3
The Two Faces of HDAC3: Neuroinflammation in Disease and Neuroprotection in Recovery3
Perspective: clinical relevance of epigenetic aging and HIV3
Role of Epigenetics in Pancreatic Ductal Adenocarcinoma3
A novel chromatin regulator signature predicts the prognosis, clinical features and immunotherapy of colon cancer3
Estrogen-induced epigenetic silencing of myotrophin reduces proliferation and is associated with chemosensitivity in hepatocellular carcinoma cells3
The Landscape of Histone Modifications in Epigenomics Since 20203
Integrative CUT&Tag-RNA-Seq Analysis of Histone Variant MacroH2A1-Dependent Orchestration of Human Induced Pluripotent Stem Cell Reprogramming3
Leveraging Epigenetics to Enhance the Efficacy of Cancer-Testis Antigen: A Potential Candidate for Immunotherapy3
A novel methylated cell-free DNA marker panel to monitor treatment response in metastatic prostate cancer3
Comprehensive analysis of ESR1 -related ceRNA axis as a novel prognostic biomarker in hepatocellular carcinoma3
Epigenetic Signaling and Crosstalk in Regulation of Gene Expression and Disease Progression2
hsa-miR-582-3p in umbilical cord blood is negatively associated with maternal exposure to childhood maltreatment2
Methylation status of LDLR , PCSK9 and LDLRAP1 is associated with cardiovascular events in familial hyperch2
Role of Epigenetic Modifications Mediated by Vitamins and Trace Elements in Inflammatory Bowel Disease2
The role of DNA methylation in directing treatment in medulloblastoma2
CRISPR-Based Epigenome Editing: Mechanisms and Applications2
Epigenetic Signature Discriminates Lymphatic Metastasis in BRAF Wild-Type Thyroid Carcinoma: Methylation Role of GRIK22
Circulating histones as potential biomarkers of MASLD-MASH-HCC progression2
Twin Study: Genotype-Dependent Epigenetic Factors Affecting Free Thyroxine Levels in the Normal Range2
A perspective on diet, epigenetics and complex diseases: where is the field headed next?2
The potential utility of cord blood DNA methylation in pediatric clinical practice2
DNA methyltransferase inhibitors in oncology: clinical progress, limitations and future directions2
Integrated Bioinformatics And Experimental Validation Reveal The Role Of Jarid2 In Ovarian Cancer2
Exploring the role of EZH2 modulation in shaping the tumor microenvironment2
PX-12 modulates vorinostat-induced acetylation and methylation marks in CAL 27 cells2
Genome-wide methylation changes upon Caco-2 cells exposure to undigested and digested titanium dioxide nanoparticles2
Circular RNA CircTTBK2 Facilitates Non-Small-Cell Lung Cancer Malignancy through the miR-873-5p/TEAD1/DERL1 Axis2
A Systematic Review and Meta-Analysis of Mirnas for the Detection of Cervical Cancer2
Evaluation of DNA methylation in BDNF , SLC6A4 , NR3C1 and FKBP5 before and 2
Emergent properties of the lysine methylome reveal regulatory roles via protein interactions and histone mimicry2
Pathological Epigenetic Events and Reversibility Review: the Intersection between Hallmarks of Aging and Developmental Origin of Health and Disease2
FAM81A Identified as a Stemness-Related Gene by Screening DNA Methylation Sites Based on Machine Learning-Accessed Stemness in Pancreatic Cancer2
DNA methylation episignatures: insight into copy number variation2
Identification of Potential Differentially Methylated Gene-Related Biomarkers in Endometriosis2
Gipc2 is a Tumor Suppressor Gene For Acute Myeloid Leukemia and Induces Apoptosis of Leukemia Cells by Regulating the Pi3K/Akt Pathway2
Epigenome-850K-wide profiling reveals peripheral blood differential methylation in term low birth weight2
Applicability of Mesenchymal Stem Cell-Derived Exosomes as a Cell-Free miRNA Therapy and Epigenetic Modifiers for Diabetes2
The Histone Methyltransferase SMYD1 is Induced by Thermogenic Stimuli in Adipose Tissue2
Unlocking diagnostic potential: DNA methylation profiling in cerebrospinal fluid for central nervous system tumors2
Epigenome-wide mediation analysis identified Cytosine-phosphate-Guanine sites linking environmental factors with diabetes indicators2
N6-Methyladenosine Methylation Regulator Fto Promotes Oxidative Stress and Induces Cell Apoptosis in Ovarian Cancer2
circ_0006988 promotes gastric cancer cell proliferation, migration and invasion through miRNA-92a-2-5p/TFAP4 axis2
DNA methylation studies in mouse models of depression: a systematic review2
Value of CtDNA Methylation Biomarkers in Diagnosis of Colorectal Tumors2
Epigenetic age acceleration and psychosocial stressors in early childhood2
Fatty Acid Metabolism-Related lncRNA Prognostic Signature for Serous Ovarian Carcinoma2
A novel subtype to predict prognosis and treatment response with DNA driver methylation–transcription in ovarian cancer2
Epigenomics May Begin To Explain In Vitro Differential Response To Hypomethylating Agents In MMR-D Hypermethylated Endometrial Cancer2
Bifaceted functions of histone methyltransferases2
Proteolysis-Targeting Chimeras Targeting Epigenetic Modulators: A Promising Strategy for Oral Cancer Therapy2
The Relevance of Epigenetics and Epigenomics to Pharmacometrics2
Novel approaches and applications in identifying DNA methylation markers of cardio-kidney-metabolic disease2
Placental DNA methylation key topics: sex- and cell-type specificity, mediation, multi-omics, and biomarker discovery2
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