OOIR: Observatory of International Research

Papers

(The TQCC of Epigenomics is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
DNMT3L Interacts with Piwi and Modulates the Expression of piRNAs in Transgenic Drosophila	53
Decoding the Year of 2023: Welcome to the 16th Volume of Epigenomics	44
Association between epigenetic aging and atrioventricular block: a two-sample Mendelian randomization study	37
The Significance of Studying Functional Lncrna in Mouse Spermatogenesis	36
Precision Epigenetics Provides a Scalable Pathway for Improving Coronary Heart Disease Care Globally	29
Lessons in Chromatin Organization and Gender Equity in Research: An Interview with Susan Gasser	27
Welcome to the 14thÂ Volume of Epigenomics	26
A Comprehensive Bioinformatic Analysis of RanBP9 Expression and Its Relation to Prognosis in Human Breast Cancer	24
Altered epigenetic landscape as infectious disease diagnostics	24
Cumulative psychosocial factors and epigenetic age acceleration in the Hispanic Community Health Study/Study of Latinos	22
Epigenetic Signature of Exposure to Maternal Trypanosoma Cruzi Infection in Cord Blood Cells from Uninfected Newborns	21
From allergens to epigenetics: how histone acetylation shapes immune gene expression in allergic diseases	20
Epigenetics in evolution and adaptation to environmental challenges: pathways for disease prevention and treatment	20
Epigenetic alterations in prostate cancer: the role of chromatin remodeling	20
Association between Alcohol Consumption and DNA Methylation in Blood: A Systematic Review of Observational Studies	20
The epigenetic roles of pirfenidone - implication in liver disease management	20
Unlocking the Epigenetic Symphony: Histone Acetylation’s Impact on Neurobehavioral Change in Neurodegenerative Disorders	19
Decoding Mitochondrial–Nuclear (epi)genome Interactions: The Emerging Role of ncRNAs	18
SET Protein as an Epigenetics Target	18
The Impact and Mechanism of TET3 Overexpression on the Progression of Hepatic Fibrosis	18
Coregulatory effects of multiple histone modifications in key ferroptosis-related genes for lung adenocarcinoma	18
Advancing epigenetic signatures as functional biomarkers in rare diseases	17
The hMeDIP-Seq Identified INPP4A as a Novel Biomarker for Eosinophilic Chronic Rhinosinusitis with Nasal Polyps	16
Age-Related Changes in Sperm DNA Methylation and their Forensic and Clinical Implications	16
Alteration of the N ⁶ -Methyladenosine Epitranscriptomic Profile in Synthetic Phthalate-Treated Human Induced Pluripotent Stem Cell-Derived Endothelial Cells	16

Epigenome-Wide Studies of Antipsychotics: A Systematic Review and Pathway Meta-Analysis	16
Promotional Effects of HIF1α and KDM3A Interaction on Vascular Smooth Muscle Cells in Thoracic Aortic Dissection	15
Targeting Tudor domains in leukemia: epigenetic insights for drug development	15
Phytochemicals in Cervical Cancer: An Epigenetic Overview	14
Epigenetic rejuvenation: a journey backwards towards an epigenomic ground state	14
How do Sphingolipids Play a Role in Epigenetic Mechanisms and Gene Expression?	14
The Study of HMOX1 DNA Methylation and Gene Expression and the Diagnostic Potential of miR-153-3p in Preeclampsia	14
Epigenetics and Cutaneous Neoplasms: From Mechanism to Therapy	14
High methylation of the same promoter of lncRNA ZNF582-AS1 / ZNF582 promotes malignant progression of esophageal cancer	13
Circular RNAs as multifaceted molecular regulators of vital activity and potential biomarkers of aging	13
Comparison of Methylation Episignatures in KMT2B - and KMT2D -Related Human Disorders	13
The eighth annual US DOHAD meeting: promising approaches in epigenetics research of early life exposures	13
Blocking RPA-based methods for the determination of CpG methylation status and detection of gene mutations	12
Matched Analysis of Detailed Peripheral Blood and Tumor Immune Microenvironment Profiles in Bladder Cancer	11
EWAS in COPD by biomass-burning smoke exposure identifies low levels of endothelin-1 by hypermethylation of EDN1	11
Evaluating the Challenges and Reproducibility of Studies Investigating DNA Methylation Signatures of Psychological Stress	11
Harnessing the Role of Epigenetic Histone Modification in Targeting Head and Neck Squamous Cell Carcinoma	11
Insights to aging prediction with AI based epigenetic clocks	11
Combined therapy targeting AR and EZH2 curbs castration-resistant prostate cancer enhancing anti-tumor T-cell response	11
Human RNA-Directed DNA Methylation Methylates High-Mobility Group Box 1 Protein-Produced DNA Gaps	11
The Epigenetics of Early Life Adversity and Trauma Inheritance: An Interview with Moshe Szyf	10
The Prognostic Role of miR-31 in Colorectal Cancer: The Results of a Meta-Analysis of 4720 Patients	10
POU2F2-mediated Upregulation of lncRNA PTPRG-AS1 Inhibits Ferroptosis in Breast Cancer Via miR-376c-3p/SLC7A11 Axis	10
ncRNAs as Biomarkers and Therapeutic Targets for Bronchiectasis	10
Chromatin Architecture Around Stroke Haplotypes Provides Evidence that Genetic Risk is Conferred Through Vascular Cells	10
The epigenetics of frailty	10
Beadchip Technology to Detect DNA Methylation in Mouse Faithfully Recapitulates Whole-Genome Bisulfite Sequencing	10
Dissecting the Nuances of Cancer Epigenomics in Liquid Biopsy	10
Exploring the Molecular Targets for Type 2 Diabetes-Induced Alzheimer’s Disease Through Bioinformatics Analysis	10
Risks and Rewards of Big-Data in Epigenomics Research: An Interview with Melanie Ehrlich	9
Three generations of epigenetic clocks in mediating the adverse effect of smoking on metabolic health	9
Blood-based DNA methylation markers for autism spectrum disorder identification using machine learning	9
Role Of Epigenetic Drugs In Sensitizing Cancers To Anticancer Therapies: Emerging Trends And Clinical Advancements	9
Integrated epigenomic exposure signature discovery	9
microRNAs and their Therapeutic Strategy in Phase I and Phase II Clinical Trials	9
Epigenetic Memory in Breast Cancer: Electrochemical Biosensor-Based Tracing of Histone H3 Acetylation Inheritance	8
DNA methylation profile to aid in the diagnosis of pancreatic ductal adenocarcinoma and its role in disease progression	8
m ⁶ A Modification and its Role in Neural Development and Neurological Diseases	8
circPlekha7 suppresses renal fibrosis via targeting miR-493-3p/KLF4	8
The Science of Hope: An Interview with Randy Jirtle	8
LINC01232 promotes ARNTL2 transcriptional activation and inhibits ferroptosis of CRC cells through p300/H3K27ac	8
The epigenetic potential of vitamin K2 in brain health	8
Transcription Factors: A Potential Therapeutic Target in Head and Neck Squamous Cell Carcinoma	8
MiR-4732-3p Prevents Lung Cancer Progression via Inhibition of the TBX15/TNFSF11 Axis	8
Epigenome-Wide Association Study of Serum Folate in Maternal Peripheral Blood Leukocytes	8
Associations Between Grimage Acceleration and Pulmonary Function in the Coronary Artery Risk Development in Young Adults (CARDIA) Study	8
Exploring Perinatal Biopsychosocial Factors and Epigenetic Age in 1-Year-Old Offspring	8
Mitochondrial D-loop Methylation Levels Inversely Correlate with Disease Duration in Amyotrophic Lateral Sclerosis	8
Combined replacement of lnc-MEG3 and miR-155 elicit tumor suppression in multiple myeloma	8
METTL3 promotes Non-Small-Cell Lung Cancer Growth and Metastasis by Inhibiting FDX1 Through Copper Death-Associated Pri-miR-21-5p Maturation	8

Epigenetics and suicidal behavior in adolescents: a critical review	8
A father’s legacy: the sperm epigenome, preimplantation development, and paternal environment	7
Dysregulation of epigenetic modifications in inborn errors of immunity	7
Epigenetics: the missing link between environmental exposures and Parkinson's disease?	7
Constructed Competitive Endogenous RNA Network and Patterns of Immune Infiltration Revealing the Prognostic Signature for Cervical Cancer	7
Dna Methylation as a Powerful Tool to Investigate the Biology and Pathology of Aging	7
Integrative analysis of a novel 5 methylated snoRNA genes prognostic signature in patients with glioma	7
cfDNA Methylation in Liquid Biopsies as Potential Testicular Seminoma Biomarker	7
The Role of N ⁶ -Methyladenosine RNA Modification in Platinum Resistance	7
Mom genes and dad genes: genomic imprinting in the regulation of social behaviors	7
EpigenomIc Technologies: An Interview with Jörg Tost	6
Psychiatry and sensation: the epigenetic links	6
PTEN Promoter Methylation And Expression In Endometrial Cancer Tissues	6
Cell-free DNA methylation patterns in aging and their association with inflamm-aging	6
RASSF1A Promotes ATM Signaling and RASSF1A Methylation is a Synthetic Lethal Marker for ATR Inhibitors	6
The Epigenetic Landscape: How Environmental Cues Shape Gene Expression	6
Dulaglutide as a Demethylating Agent to Improve the Outcome of Breast Cancer	6
Correlation among maternal risk factors, gene methylation and disease severity in females with autism spectrum disorder	6
Association between imprinting disorders and assisted reproductive technologies	6
Combination Therapy and Noncoding RNAs: A New Era of Cancer Personalized Medicine	6
The Epigenetics Orchestra of Notch Signaling: A Symphony for Cancer Therapy	6
DNA methylation associations with cognitive function in early-stage hormone receptor-positive breast cancer patients	6
Epigenetic landscape of intestinal cell line HT29 cocultured with Lacticaseibacillus	6
The Role of H3K9 Acetylation and Gene Expression in Different Brain Regions of Alzheimer’s Disease Patients	5
Clinical Uses of Epigenetics in Cardiology and Cardiothoracic Surgery: An Update	5
Transcriptome Profiling and ceRNA Network of Small Extracellular Vesicles from Resting and Degranulated Mast Cells	5
Methylation changes of liver DNA during the formation of gallstones	5
Impact of prematurity on LINE-1 promoter methylation	5
Epigenomic Impacts of Meditative Practices	5
Epigenomic mechanisms of dietary prescriptions for obesity therapy	5
Comprehensive Analysis of Epigenetic Modifications and Immune-Cell Infiltration In Tissues from Patients With Systemic Lupus Erythematosus	5
Epigenetic Disruption of Histone Deacetylase-2 Accelerated Apoptotic Signaling and Retarded Malignancy in Gastric Cells	5
Epigenetics of cerebrovascular diseases: an update review of clinical studies	5
A narrative review of epigenetic marker in H3K27ac and its emerging potential as a therapeutic target in cancer	5
DNA methylation-based health predictors: advances, applications, and perspectives	5
Super-enhancers: drivers of cells’ identities and cells’ debacles	5
tRNA-derived RNAs in human milk extracellular vesicles and associations with breastfeeding variables and maternal diet	5
Placental expression and methylation of angiogenic factors in assisted reproductive technology pregnancies from India	5
The Ups and Downs of DNA Methylation: An Interview with Gerd Pfeifer	5
Targeting TET enzymes in ovarian cancer: epigenetic regulation, chemoresistance, and therapeutic opportunities	5
Bridging the gap: R-loop mediated genomic instability and its implications in neurological diseases	5
The regulation of microRNAs on chemoresistance in triple-negative breast cancer: a recent update	5
Epigenetic Regulation of Vitamin D Deficiency	5
Development and validation of a novel cell type estimation method for targeted bisulfite sequencing data	5
Accurate interpretation of inosines in RNAs: recognized as G is more than basepairing with C	5
PEMT Variants are Associated with Nonsyndromic Cleft Lip with or without Cleft Palate in Chile	5
MDM2 and DNMT1 inhibitors induce neuroblastoma cell death through p53-dependent and independent pathways	5
Breaking the epigenetic code with MARCS: the Modification Atlas of Regulation by Chromatin States	5
Dna Methylation Episignatures are Sensitive and Specific Biomarkers for Detection of Patients with Kat6A / Kat6B Variants	5