Expert Review of Clinical Pharmacology

Article	Citations
Strategies for lowering lipoprotein(a): a spotlight on novel pharmacological treatments	177
Personalizing tamoxifen therapy in adjuvant therapy: a brief summary of the ongoing discussion	56
Why is diagnosis, investigation, and improved management of kidney stone disease important? Non-pharmacological and pharmacological treatments for nephrolithiasis	43
Renin angiotensin aldosterone inhibitors in the treatment of proteinuria in children with congenital anomalies of the kidney and urinary tract: more evidence needed	41
Risk of new onset diabetes mellitus with pitavastatin as compared to atorvastatin and rosuvastatin: a systematic review and meta-analysis	36
What is the potential for abuse of lisdexamfetamine in adults? A preclinical and clinical literature review and expert opinion	30
Effects of the augmentation with quetiapine or olanzapine on the metabolism of duloxetine: a retrospective analysis	30
Therapeutic drug monitoring of antiretroviral therapy: current progresses and future directions	30
Clinical pharmacology of antiplatelet drugs	30
Prostate cancer and novel pharmacological treatment options–what’s new for 2022?	30
Reducing the risk of death – a possible outcome in COPD patients	29
Pharmacological and clinical profile of ravulizumab 100 mg/mL formulation for paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome	29
JAK inhibitors in dermatology: the road travelled and path ahead, a narrative review	29
Sodium-glucose cotransporter 2 inhibitors in frail, older people with type 2 diabetes and heart failure: do we have enough evidence to confidently support the use?	27
The pharmacotherapeutics of sarcoidosis	27
Brimonidine tartrate ophthalmic solution 0.025% for redness relief: an overview of safety and efficacy	27
Hugan tablets for the treatment of RUCAM based drug-induced liver injury: a propensity score matching analysis using a nationwide database	25
Fetal safety of medications used in treating infertility	25
Cannabidiol drug interaction considerations for prescribers and pharmacists	25
Amylin analogs for the treatment of obesity without diabetes: present and future	21
Role of tenecteplase in ischemic stroke after 4.5 hours: an evaluation of the TRACE-III trial	21
Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective	20
Dostarlimab for the treatment of advanced endometrial cancer	20
The thiazide-like diuretic chlorthalidone as an alternative evidence-based therapy for resistant hypertension in patients with stage 4 chronic kidney disease	20
Clinical efficacy and safety of topical difamilast in the treatment of patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials	20

Broadening access to tenofovir alafenamide for the treatment and prevention of HIV-1 infection	20
Nirmatrelvir/Ritonavir and molnupiravir: an update on COVID-19 antivirals in the Omicron era	19
Complications related to oral corticosteroid use in asthma patients: a retrospective cohort study	19
Pharmacogenetics-based population pharmacokinetic analysis for dose optimization of ritonavir-boosted atazanavir in Thai adult HIV-infected patients	18
Reply to: The risk for genito-urinary infections with sodium-glucose cotransporter-2 inhibitors: duration rather than dose matter?	18
Association between sodium-glucose cotransporter 2 inhibitors and eye disorders: a systematic review and meta-analysis	17
Pharmacological strategies for the management of the antisocial personality disorder	17
Voclosporin: a novel calcineurin inhibitor for the treatment of lupus nephritis	17
Recent pharmacological approaches for the treatment of renal cell carcinoma	17
OPTIMA-ID: development and validation of a medicine optimization tool for older adults with intellectual disability	17
Hydroxyurea in the sickle cell disease modern era	16
Pediatric attention deficit hyperactivity disorder (ADHD): 2022 updates on pharmacological management	16
A profile of azetukalner for the treatment of epilepsy: from pharmacology to potential for therapy	16
Drug-drug interactions associated with FLT3 inhibitors for acute myeloblastic leukemia: current landscape	16
Effect of laparoscopic sleeve gastrectomy on drug pharmacokinetics	16
Melflufen for the treatment of multiple myeloma	16
Population pharmacokinetic modeling and exposure-response analysis of anrikefon: insights and implications in clinical analgesia	15
Current status and prospects of IL-6–targeting therapy	15
Methenamine Hippurate in UTI management: a reemerging pharmacological strategy	15
Clinical pharmacology of SGLT-2 inhibitors in heart failure	15
Methotrexate polyglutamates	14
A narrative review of non-racemic amisulpride (SEP-4199) for treatment of depressive symptoms in bipolar disorder and LB-102 for treatment of schizophrenia	14
Emerging pharmacological options in the treatment of idiopathic pulmonary fibrosis (IPF)	14
Pharmacogenomics – a minor rather than major force in clinical medicine	14
Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic review and meta-analysis	13
Prevention of colistin induced nephrotoxicity: a review of preclinical and clinical data	13
FLOT vs CROSS in localized esophageal adenocarcinoma: what is the current best strategy?	13
Risk factors for a broken heart: understanding drug-induced causes for Takotsubo syndrome and pharmacological treatment options	13
Physiologically-based pharmacokinetic modeling to predict the exposure and provide dosage regimens of adalimumab in patients with juvenile idiopathic arthritis	13
A systematic review and meta-analysis of users versus non-users: unveiling the influence of proton pump inhibitors on capecitabine efficacy in colorectal cancer	13
Phosphatidylinositol 3 kinase inhibitor-related pneumonitis: a systematic review and meta-analysis	13
Efficacy and safety of tislelizumab for malignant solid tumor: a systematic review and meta-analysis of phase III randomized trials	13
Sodium zirconium cyclosilicate for the management of chronic hyperkalemia in kidney disease, a novel agent	12
Antimicrobial safety considerations in critically ill patients: part II: focused on anti-microbial toxicities	12
The nocebo phenomenon in the COVID-19 pandemic: a nocebodemic effect	12
An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry	12
Real-world clinical effectiveness of once-weekly semaglutide in patients with type 2 diabetes: a systematic literature review	12
Revolutionizing diabetes care: unveiling tirzepatide’s potential in glycemic control and beyond	11
Efficacy and safety of dupilumab in chronic rhinosinusitis with nasal polyps: a systematic review and meta-analysis	11
Optimization of secukinumab dose regimens in patients with moderate-to-severe plaque psoriasis via exposure-response modeling	11
Is therapeutic drug monitoring a dancing partner for TNF-α inhibitors in real-world practice? Answers from an updated systematic review and meta-analysis	11
Designer benzodiazepines: an update	11
Pharmacological and safety profile of a prolonged-release lanreotide formulation in acromegaly	11
Genito-urinary infectious adverse events related to sodium glucose cotransporter-2 inhibitors: a network meta-analysis and meta-regression	10
Immunotherapy of High Risk Non-Muscle Invasive Bladder Cancer	10
TYK2 as a novel therapeutic target in psoriasis	10
Gender differences in new hypoglycemic drug effects on renal outcomes: a systematic review	10
Biomarker discovery in acetaminophen hepatotoxicity: leveraging single-cell transcriptomics and mechanistic insight	10
Pharmacokinetic interaction of quetiapine and lamotrigine – victim and perpetrator?	10
Recent advances in the pharmacological management of sepsis-associated acute kidney injury	10

The pharmacotherapeutic options in patients with catecholamine-resistant vasodilatory shock	9
Advances in pharmacokinetic-pharmacodynamic modelling for pediatric drug development: extrapolations and exposure-response analyses	9
Clinical pharmacology of siRNA therapeutics: current status and future prospects	9
Signal mining study of severe cutaneous adverse events of valaciclovir or acyclovir based on the FAERS database	9
Keeping up with venetoclax for leukemic malignancies: key findings, optimal regimens, and clinical considerations	9
Statin-related neurocognitive disorder: a real-world pharmacovigilance study based on the FDA adverse event reporting system	9
Encouraging appropriate use of proton pump inhibitors: existing initiatives and proposals for the future	9
Interstitial lung disease associated with anti-HER2 anti-body drug conjugates: results from clinical trials and the WHO's pharmacovigilance database	9
Reliance is key to effective access and oversight of medical products in case of public health emergencies	9
Practical challenges and considerations in adopting biosimilars in oncology clinical practice within a large healthcare system	9
Golimumab retention in patients with psoriatic arthritis and axial spondyloarthritis: evidence from up to a decade of follow-up	9
Dasiglucagon for treating severe hypoglycemia in patients with diabetes	9
Antimicrobial safety considerations in critically ill patients: part I: focused on acute kidney injury	8
The future of pharmacology education: The Veterinary Educators in Pharmacology Special Interest Group (VEPSIG)	8
Inhaler technique in asthma and COPD: challenges and unmet knowledge that can contribute to suboptimal use in real life	8
Availability and evaluation of medication management resources for carers of people with dementia: a scoping review with an environmental scan	8
Adverse clinical outcomes associated with drug-related hospitalizations in people with dementia	8
Pharmacological treatment for transforming growth factor beta induced corneal dystrophies: what is the way forward?	8
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause	8
Blinding and expectancy confounds in psychedelic randomized controlled trials	8
Opioid use disorder in pediatric populations: considerations for perioperative pain management and precision opioid analgesia	8
Clinical outcomes of oral anticoagulant discontinuation in atrial fibrillation: a systematic review and meta-analysis	8
Current understanding of the etiology of cyclic vomiting syndrome and therapeutic strategies in its management	8
Intravitreal immunotherapy in non-infectious uveitis: an update	8
Clozapine for treatment refractory catatonia in individuals with autism spectrum disorder: a retrospective chart review study	8
An overview on disease modifying and symptomatic drug treatments for multiple sclerosis	7
Emerging pharmacological strategies for treating and preventing mpox	7
Quantitative effects of sodium-glucose cotransporter-2 inhibitors on liver functions in patients with nonalcoholic fatty liver disease	7
131-I-metaiodobenzylguanidine and chemotherapy for advanced neuroblastoma	7
Effects of single-nucleotide polymorphism on the pharmacokinetics and pharmacodynamics of metformin	7
Optimizing outcomes and managing adverse events in locally advanced or metastatic urothelial cancer: a clinical pharmacology perspective	7
The impact of pregnancy-related hormonal and physiological changes on antiseizure medications: expert perspective	7
Considerations when prescribing opioid agonist therapies for people living with HIV	7
The ketamine chameleon: history, pharmacology, and the contested value of experience	7
Closing the gaps in the access to quality-assured medicines for global health: The case for oxytocin for postpartum haemorrhage	7
The changes of IgE levels in type 2 inflammatory diseases after treatment of dupilumab: a systematic review and meta-analysis	7
Next-generation sequencing in pharmacogenomics – fit for clinical decision support?	7
Perspectives on deprescribing in older people with type 2 diabetes and/or cardiovascular conditions: challenges from healthcare provider, patient and caregiver perspective, and interventions to suppor	7
Detrimental impact of gastric acid suppressants on vascular endothelial growth factor receptor tyrosine kinase inhibitors efficacy: evidence from a systematic review and meta-analysis	7
The impact of body composition on treatment in ovarian cancer: a current insight	7
Comparing the renal outcomes in patients with atrial fibrillation receiving different oral anticoagulants	7
Implementing pharmacogenetics in clinical trials: considerations about current methodological, ethical, and regulatory challenges	7
The need for inhaled phosphodiesterase inhibitors in chronic obstructive pulmonary disease	7
Getting immunosuppression just right: the role of clinical biomarkers in predicting patient response post solid organ transplantation	7
Biosimilar development and review process in the BRICS-TM countries: Proposal for a standardized model to improve regulatory performance	7
Coadministration of silymarin with iron chelators in transfusion-dependent β-thalassemia patients: a systematic review and meta-analysis for effect on iron overload	7
Impact of SGLT2 inhibitors on the kidney in people with type 2 diabetes and severely increased albuminuria	7
Intraperitoneal therapy for gastric cancer peritoneal carcinomatosis	7
Novel and emerging treatment strategies for lupus nephritis	7
Epoprostenol for the treatment of pulmonary arterial hypertension	7
Extending the ambit of SGLT2 inhibitors beyond diabetes: a review of clinical and preclinical studies on non-diabetic kidney disease	7
Treatment and prevention of influenza in geriatric patients	7
Molecular docking and dynamics study to explore phytochemical ligand molecules against the main protease of SARS-CoV-2 from extensive phytochemical datasets	6
The role of glucagon-like peptide-1 receptor agonists in nonalcoholic fatty liver disease	6
WHO collaborative registration procedure using stringent regulatory authorities’ medicine evaluation: reliance in action?	6
The evolution of clinical trials for pediatric pulmonary hypertension: are the needs of patients and their caregivers being met?	6
Effects of anti-inflammatory treatment on efficacy of selective laser trabeculoplasty: a systematic review and meta-analysis	6
The outcomes of considering goals of care in medication reviews for older adults: a systematic review	6
Therapeutic approach to neurological manifestations of Angelman syndrome	6
Correction	6
Challenges, unmet needs and future directions – a critical evaluation of the clinical trial landscape in schizophrenia research	6
Novel pharmacological therapies for the treatment of endometriosis	6
Dried blood spot sampling for therapeutic drug monitoring: challenges and opportunities	6
Systematic reviews of randomized controlled trials of cannabinoid products in chronic pain conditions and for symptoms associated with multiple sclerosis: what do they tell us?	6
Machine learning, pharmacogenomics, and clinical psychiatry: predicting antidepressant response in patients with major depressive disorder	5
Bridging the gap in cardiovascular care in diabetic patients: are cardioprotective antihyperglycemic agents underutilized?	5
A single inhaler triple therapy fluticasone furoate/umeclidinium/vilanterol for the treatment of COPD	5
A model based on machine learning for the prediction of cyclosporin A trough concentration in Chinese allo-HSCT patients	5
3D printing – an alternative strategy for pediatric medicines	5
Treatment options following metformin in primary prevention populations with type 2 diabetes: which is the right road to take?	5
The heterogeneity of metabolic syndrome presentation and challenges this causes in its pharmacological management: a narrative review focusing on principal risk modifiers	5
Comparison of the relative efficacy of different biologics in different body areas in patients with moderate to severe psoriasis receiving biologics and tofacitinib in phase 3 randomized controlled tr	5
Correction	5
Pharmacological approaches to prevent vertical transmission of HIV and HBV	5
Ribosomopathies and cancer: pharmacological implications	5
Population pharmacokinetics of omeprazole in obese and normal-weight adults	5
Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations	5
Centering the patient in decisions about opioid tapering	5
The role of CYP2C19 genotyping to guide antiplatelet therapy following ischemic stroke or transient ischemic attack	5
Anticholinergics and falls in older adults	5

Emerging insights and future prospects for therapeutic application of siRNA targeting angiotensinogen in hypertension	5
Pharmacological profile of once-weekly injectable semaglutide for chronic weight management	5
Clostridioides difficile resistance to antibiotics, including post-COVID-19 data	5
Vestibular function in children with generalized epilepsy and treated with valproate	5
Optimization of potassium management in patients with chronic kidney disease and type 2 diabetes on finerenone	5
Sex and gender differences in the treatment of arterial hypertension	5
The effect of inhaled corticosteroids on the outcomes of patients with COVID-19: A systematic review and meta-analysis of randomized controlled trials	5
Edoxaban for the treatment of pulmonary embolism in hospitalized COVID-19 patients	5
Psychiatric and non-psychiatric drugs causing false-positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS	5
Effect of Wuzhi capsules on cyclosporine A concentration in children with aplastic anemia immunotherapy: a single-center observational study	5
Updates in the diagnosis and practical management of allergic rhinitis	4
Nephroprotective effects of febuxostat and/or mirtazapine against gentamicin-induced nephrotoxicity through modulation of ERK 1/2, NF-κB and MCP1	4
Influence of N -acetyltransferase 2 polymorphisms and clinical variables on liver function profile of tuberculosis patients	4
Significant predictors for olanzapine pharmacokinetics: a systematic review of population pharmacokinetic studies	4
Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes	4
Targeting the spectrum of immune checkpoints in prostate cancer	4
STOPP/START criteria for potentially inappropriate medications/potential prescribing omissions in older people: uptake and clinical impact	4
A profile of delafloxacin in the treatment of adults with community-acquired bacterial pneumonia	4
Type of proteinuria might be essential for RAAS-I treatment in children with CAKUT	4
Renin–angiotensin system inhibition and mortality in patients undergoing dialysis with coronary artery disease: insights from a multi-center observational study	4
Artificial intelligence-based model for dose prediction of sertraline in adolescents: a real-world study	4
Efficacy and safety of insulin detemir versus glargine in patients with diabetes: a systematic review and meta-analysis	4
Therapeutic drug monitoring-guided dosing for pediatric cystic fibrosis patients: recent advances and future outlooks	4
An update on the clinical pharmacology of kratom: uses, abuse potential, and future considerations	4
The effect of different levothyroxine administration regimens on thyroid hormone levels: a systematic review, pairwise, and network meta-analysis	4
Effectiveness of statins in people living with HIV: a systematic review and meta-analysis of randomized controlled trials	4
Optimizing ganciclovir and valganciclovir dosing regimens in pediatric patients with cytomegalovirus infection: a spotlight on therapeutic drug monitoring	4
Biosimilar and generic formulations of novel antidiabetic drugs: the role of liraglutide in clinical pharmacology of type 2 diabetes	4
Scoping review of the availability and uptake of disease modifying therapies in children and adolescents with multiple sclerosis	4
Therapeutic effects of topical cetirizine in the treatment of female pattern hair loss: a randomized controlled noninferiority trial	4
A review of alternative intravenous acetylcysteine regimens for acetaminophen overdose	4
Artificial intelligence and machine learning in clinical pharmacological research	4
Snakebite-associated thrombotic microangiopathy: a spotlight on pharmaceutical interventions	4
A comprehensive strategy to address shortage of Erwinia asparaginase in pediatric acute lymphoblastic leukemia	4
Growing role of SGLT2i in heart failure: evidence from clinical trials	4
Tocilizumab for the treatment of non‐critical COVID‐19 pneumonia: an overview of the rationale and clinical evidence to date	4
Perspectives on deprescribing in palliative care	4
The efficacy and toxicity of mirvetuximab soravtansine, a novel antibody-drug conjugate, in the treatment of advanced or recurrent ovarian cancer: a meta-analysis	4
Correction	4
Dual pathway inhibition in patients with atherosclerotic disease: pharmacodynamic considerations and clinical implications	3
Drug related adverse event assessment in neonates in clinical trials and clinical care	3
Samidorphan for the treatment of weight gain associated with olanzapine in patients with schizophrenia and bipolar disorder	3
Pharmacological management of testosterone deficiency in men current advances and future directions	3
The era of lenalidomide maintenance therapy in multiple myeloma: settings for achieving best outcomes	3
Novel insights into molecular and cellular aspects of delayed drug hypersensitivity reactions	3
Patient initiation and maintenance of GLP-1 RAs for treatment of obesity	3
The search for blood biomarkers useful in treating atopic dermatitis patients	3
A review of recent advances in the treatment of adults with complicated urinary tract infection	3
The evolving landscape of PARP inhibitors in castration-resistant prostate cancer: a spotlight on treatment combinations	3
Who is blind in psychedelic research? Letter to the editor regarding: blinding and expectancy confounds in psychedelic randomized controlled trials	3
Potential approaches using teneligliptin for the treatment of type 2 diabetes mellitus: current status and future prospects	3
Evogliptin for the treatment option for type 2 diabetes: an update of the literature	3
Is ranitidine necessary as premedication for regimens containing paclitaxel? A non-inferiority study	3
Association between myocarditis and antipsychotics other than clozapine: a systematic literature review and a pharmacovigilance study using VigiBase	3
How to handle the delayed or missed dose of rivaroxaban in patients with non-valvular atrial fibrillation: model-informed remedial dosing	3
Exploring the room for repurposed hydroxychloroquine to impede COVID-19: toxicities and multipronged combination approaches with pharmaceutical insights	3
Regional variation in longitudinal trajectories of primary care opioids prescribing across Health Boards in Scotland: a population-based study	3
Set and setting predict psychopathology, wellbeing and meaningfulness of psychedelic experiences: a correlational study	3
Comparison of weight loss and adverse events of obesity drugs in children and adolescents: a systematic review and meta-analysis	3
Analyzing the clinical efficacy and safety of levocetirizine based on its receptor occupancy, intraclass comparison and role in the treatment of CSU: an AROG consensus statement	3
Updates in innovation of the treatment of pyoderma gangrenosum	3
Clinical pharmacology and PK/PD translation of the second-generation Bruton’s tyrosine kinase inhibitor, zanubrutinib	3
Semaglutide and smoking cessation in individuals with type 2 diabetes mellitus: there is no smoke without fire!	3
Impact of COVID-19 pandemic on the prescribing pattern of oral anticoagulants in the English primary care setting: a population-based segmented interrupted time series analysis of over 53 million indi	3
Stimulant and hallucinogenic novel psychoactive substances; an update	3
The effect of epilepsy and antiseizure medications on cardiac autonomic functions in children with epilepsy	3
Peroxisome proliferator-activated receptor-gamma (PPARγ) and its immunomodulation function: current understanding and future therapeutic implications	3
Letermovir and new horizons in prevention of post-transplant CMV	3
The outcomes of goal-oriented medication reviews for the elderly: current research and future directions	3
JAK inhibitors in vitiligo: what they hit and what they miss - an immunopathogenesis based exposition of existing evidence	3
Desmopressin acetate the first sublingual tablet to treat nocturia due to nocturnal polyuria	3
Sodium-glucose co-transporter 2 inhibition and acute myocardial infarction: the DAPA-MI and EMPACT-MI trials	3
Clinical considerations when switching antiretroviral therapy	3
Efficacy and safety of oliceridine treatment in patients with postoperative pain: a systematic review and meta-analysis of randomized controlled trials	3
Predicting drug response and toxicity in metastatic colorectal cancer: the role of germline markers	3
A profile of safety and efficacy of fezolinetant for the treatment of menopausal vasomotor symptoms	3
Gene therapy in cardiology: pioneering a new era in medical ethics and patient care	3
Finerenone: a mineralocorticoid receptor antagonist for the treatment of chronic kidney disease associated with type 2 diabetes	3
The Role of testosterone treatment in patients with metabolic disorders	3
The association between the use of sodium glucose cotransporter 2 inhibitor and the risk of diabetic retinopathy and other eye disorders: a systematic review and meta-analysis	3
Comparative effectiveness and safety of inhaled corticosteroid plus long-acting β 2 -agonist fixed-dose combinations vs. long-acting muscarinic antagonist in bronchi	3
A scoping review of the clinical utility of adverse drug reaction causality analysis tools for use in the hospital setting	3
Association between statins’ exposure with incidence and prognosis of gastric cancer: an updated meta‐analysis	3
Utilizing clinical pharmacology in the drug repurposing arena: a look into COVID-19	3
Response to letter to the editor: therapeutic importance of proteinuria classification in children with congenital anomalies of the kidney and urinary tract	3
A scoping review of legibility of hand-written prescriptions and drug-orders: the writing on the wall	3