Expert Review of Clinical Pharmacology

Article	Citations
Strategies for lowering lipoprotein(a): a spotlight on novel pharmacological treatments	196
Personalizing tamoxifen therapy in adjuvant therapy: a brief summary of the ongoing discussion	57
Why is diagnosis, investigation, and improved management of kidney stone disease important? Non-pharmacological and pharmacological treatments for nephrolithiasis	46
Renin angiotensin aldosterone inhibitors in the treatment of proteinuria in children with congenital anomalies of the kidney and urinary tract: more evidence needed	41
Risk of new onset diabetes mellitus with pitavastatin as compared to atorvastatin and rosuvastatin: a systematic review and meta-analysis	39
Therapeutic drug monitoring of antiretroviral therapy: current progresses and future directions	34
What is the potential for abuse of lisdexamfetamine in adults? A preclinical and clinical literature review and expert opinion	31
Management of polypharmacy through deprescribing in older patients: a review of the role of AI tools	31
Sodium-glucose cotransporter 2 inhibitors in frail, older people with type 2 diabetes and heart failure: do we have enough evidence to confidently support the use?	31
Clinical pharmacology of antiplatelet drugs	30
Pharmacological and clinical profile of ravulizumab 100 mg/mL formulation for paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome	30
Effects of the augmentation with quetiapine or olanzapine on the metabolism of duloxetine: a retrospective analysis	28
Reducing the risk of death – a possible outcome in COPD patients	28
Prostate cancer and novel pharmacological treatment options–what’s new for 2022?	28
JAK inhibitors in dermatology: the road travelled and path ahead, a narrative review	27
Sparsentan: a dual endothelin and angiotensin II receptor antagonist approved for IgA nephropathy	26
The pharmacotherapeutics of sarcoidosis	26
Dostarlimab for the treatment of advanced endometrial cancer	24
Fetal safety of medications used in treating infertility	23
Amylin analogs for the treatment of obesity without diabetes: present and future	23
Role of tenecteplase in ischemic stroke after 4.5 hours: an evaluation of the TRACE-III trial	21
Hugan tablets for the treatment of RUCAM based drug-induced liver injury: a propensity score matching analysis using a nationwide database	20
Cannabidiol drug interaction considerations for prescribers and pharmacists	20
Broadening access to tenofovir alafenamide for the treatment and prevention of HIV-1 infection	20
Brimonidine tartrate ophthalmic solution 0.025% for redness relief: an overview of safety and efficacy	20

Clinical efficacy and safety of topical difamilast in the treatment of patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials	20
Complications related to oral corticosteroid use in asthma patients: a retrospective cohort study	19
The thiazide-like diuretic chlorthalidone as an alternative evidence-based therapy for resistant hypertension in patients with stage 4 chronic kidney disease	19
Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective	19
Nirmatrelvir/Ritonavir and molnupiravir: an update on COVID-19 antivirals in the Omicron era	18
Pharmacogenetics-based population pharmacokinetic analysis for dose optimization of ritonavir-boosted atazanavir in Thai adult HIV-infected patients	18
Reply to: The risk for genito-urinary infections with sodium-glucose cotransporter-2 inhibitors: duration rather than dose matter?	18
Recent pharmacological approaches for the treatment of renal cell carcinoma	17
Voclosporin: a novel calcineurin inhibitor for the treatment of lupus nephritis	17
Pharmacological strategies for the management of the antisocial personality disorder	17
OPTIMA-ID: development and validation of a medicine optimization tool for older adults with intellectual disability	16
Melflufen for the treatment of multiple myeloma	16
Drug-drug interactions associated with FLT3 inhibitors for acute myeloblastic leukemia: current landscape	16
Association between sodium-glucose cotransporter 2 inhibitors and eye disorders: a systematic review and meta-analysis	16
Pediatric attention deficit hyperactivity disorder (ADHD): 2022 updates on pharmacological management	16
Hydroxyurea in the sickle cell disease modern era	16
Effect of laparoscopic sleeve gastrectomy on drug pharmacokinetics	16
Methenamine Hippurate in UTI management: a reemerging pharmacological strategy	14
Population pharmacokinetic modeling and exposure-response analysis of anrikefon: insights and implications in clinical analgesia	14
A profile of azetukalner for the treatment of epilepsy: from pharmacology to potential for therapy	14
Current status and prospects of IL-6–targeting therapy	14
Emerging pharmacological options in the treatment of idiopathic pulmonary fibrosis (IPF)	14
Clozapine for older adults with severe mental illness: a systematic review and expert recommendations for clinical practice	14
Clinical pharmacology of SGLT-2 inhibitors in heart failure	14
Pharmacogenomics – a minor rather than major force in clinical medicine	13
Methotrexate polyglutamates	13
Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic review and meta-analysis	12
FLOT vs CROSS in localized esophageal adenocarcinoma: what is the current best strategy?	12
A narrative review of non-racemic amisulpride (SEP-4199) for treatment of depressive symptoms in bipolar disorder and LB-102 for treatment of schizophrenia	12
Real-world clinical effectiveness of once-weekly semaglutide in patients with type 2 diabetes: a systematic literature review	12
A systematic review and meta-analysis of users versus non-users: unveiling the influence of proton pump inhibitors on capecitabine efficacy in colorectal cancer	12
Early response is a strong predictor of the long-term response in psoriasis patients receiving risankizumab or guselkumab in the real-world: a retrospective analysis	12
Revolutionizing diabetes care: unveiling tirzepatide’s potential in glycemic control and beyond	11
An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry	11
Risk factors for a broken heart: understanding drug-induced causes for Takotsubo syndrome and pharmacological treatment options	11
Designer benzodiazepines: an update	11
Efficacy and safety of tislelizumab for malignant solid tumor: a systematic review and meta-analysis of phase III randomized trials	11
The nocebo phenomenon in the COVID-19 pandemic: a nocebodemic effect	11
Physiologically-based pharmacokinetic modeling to predict the exposure and provide dosage regimens of adalimumab in patients with juvenile idiopathic arthritis	11
Antimicrobial safety considerations in critically ill patients: part II: focused on anti-microbial toxicities	11
Phosphatidylinositol 3 kinase inhibitor-related pneumonitis: a systematic review and meta-analysis	11
Biomarker discovery in acetaminophen hepatotoxicity: leveraging single-cell transcriptomics and mechanistic insight	10
Pharmacokinetic interaction of quetiapine and lamotrigine – victim and perpetrator?	10
Is therapeutic drug monitoring a dancing partner for TNF-α inhibitors in real-world practice? Answers from an updated systematic review and meta-analysis	10
Optimization of secukinumab dose regimens in patients with moderate-to-severe plaque psoriasis via exposure-response modeling	10
Recent advances in the pharmacological management of sepsis-associated acute kidney injury	10
Efficacy and safety of dupilumab in chronic rhinosinusitis with nasal polyps: a systematic review and meta-analysis	10
Gender differences in new hypoglycemic drug effects on renal outcomes: a systematic review	10
Clinical pharmacology of siRNA therapeutics: current status and future prospects	9
Encouraging appropriate use of proton pump inhibitors: existing initiatives and proposals for the future	9

Interstitial lung disease associated with anti-HER2 anti-body drug conjugates: results from clinical trials and the WHO's pharmacovigilance database	9
Reliance is key to effective access and oversight of medical products in case of public health emergencies	9
Pharmacological and safety profile of a prolonged-release lanreotide formulation in acromegaly	9
Genito-urinary infectious adverse events related to sodium glucose cotransporter-2 inhibitors: a network meta-analysis and meta-regression	9
TYK2 as a novel therapeutic target in psoriasis	9
Signal mining study of severe cutaneous adverse events of valaciclovir or acyclovir based on the FAERS database	9
Golimumab retention in patients with psoriatic arthritis and axial spondyloarthritis: evidence from up to a decade of follow-up	9
Dasiglucagon for treating severe hypoglycemia in patients with diabetes	9
Advances in pharmacokinetic-pharmacodynamic modelling for pediatric drug development: extrapolations and exposure-response analyses	9
Opioid use disorder in pediatric populations: considerations for perioperative pain management and precision opioid analgesia	8
Current understanding of the etiology of cyclic vomiting syndrome and therapeutic strategies in its management	8
Clinical outcomes of oral anticoagulant discontinuation in atrial fibrillation: a systematic review and meta-analysis	8
Clozapine for treatment refractory catatonia in individuals with autism spectrum disorder: a retrospective chart review study	8
The pharmacotherapeutic options in patients with catecholamine-resistant vasodilatory shock	8
Statin-related neurocognitive disorder: a real-world pharmacovigilance study based on the FDA adverse event reporting system	8
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause	8
Adverse clinical outcomes associated with drug-related hospitalizations in people with dementia	8
The future of pharmacology education: The Veterinary Educators in Pharmacology Special Interest Group (VEPSIG)	8
Keeping up with venetoclax for leukemic malignancies: key findings, optimal regimens, and clinical considerations	8
Practical challenges and considerations in adopting biosimilars in oncology clinical practice within a large healthcare system	8
Antimicrobial safety considerations in critically ill patients: part I: focused on acute kidney injury	8
Intravitreal immunotherapy in non-infectious uveitis: an update	7
Intraperitoneal therapy for gastric cancer peritoneal carcinomatosis	7
Blinding and expectancy confounds in psychedelic randomized controlled trials	7
Inhaler technique in asthma and COPD: challenges and unmet knowledge that can contribute to suboptimal use in real life	7
Quantitative effects of sodium-glucose cotransporter-2 inhibitors on liver functions in patients with nonalcoholic fatty liver disease	7
Impact of SGLT2 inhibitors on the kidney in people with type 2 diabetes and severely increased albuminuria	7
Treatment and prevention of influenza in geriatric patients	7
Biosimilar development and review process in the BRICS-TM countries: Proposal for a standardized model to improve regulatory performance	7
Considerations when prescribing opioid agonist therapies for people living with HIV	7
Availability and evaluation of medication management resources for carers of people with dementia: a scoping review with an environmental scan	7
Pharmacological treatment for transforming growth factor beta induced corneal dystrophies: what is the way forward?	7
Perspectives on deprescribing in older people with type 2 diabetes and/or cardiovascular conditions: challenges from healthcare provider, patient and caregiver perspective, and interventions to suppor	7
Comparing the renal outcomes in patients with atrial fibrillation receiving different oral anticoagulants	7
The impact of pregnancy-related hormonal and physiological changes on antiseizure medications: expert perspective	7
Implementing pharmacogenetics in clinical trials: considerations about current methodological, ethical, and regulatory challenges	7
Novel and emerging treatment strategies for lupus nephritis	7
Effects of single-nucleotide polymorphism on the pharmacokinetics and pharmacodynamics of metformin	7
Optimizing outcomes and managing adverse events in locally advanced or metastatic urothelial cancer: a clinical pharmacology perspective	7
Hormonal contraception, past, present, and future part 1: the early path – facts, stories, and controversies	7
Detrimental impact of gastric acid suppressants on vascular endothelial growth factor receptor tyrosine kinase inhibitors efficacy: evidence from a systematic review and meta-analysis	7
131-I-metaiodobenzylguanidine and chemotherapy for advanced neuroblastoma	7
Extending the ambit of SGLT2 inhibitors beyond diabetes: a review of clinical and preclinical studies on non-diabetic kidney disease	7
The changes of IgE levels in type 2 inflammatory diseases after treatment of dupilumab: a systematic review and meta-analysis	7
An overview on disease modifying and symptomatic drug treatments for multiple sclerosis	6
Challenges, unmet needs and future directions – a critical evaluation of the clinical trial landscape in schizophrenia research	6
The outcomes of considering goals of care in medication reviews for older adults: a systematic review	6
The role of glucagon-like peptide-1 receptor agonists in nonalcoholic fatty liver disease	6
Correction	6
Molecular docking and dynamics study to explore phytochemical ligand molecules against the main protease of SARS-CoV-2 from extensive phytochemical datasets	6
Next-generation sequencing in pharmacogenomics – fit for clinical decision support?	6
Getting immunosuppression just right: the role of clinical biomarkers in predicting patient response post solid organ transplantation	6
The ketamine chameleon: history, pharmacology, and the contested value of experience	6
Closing the gaps in the access to quality-assured medicines for global health: The case for oxytocin for postpartum haemorrhage	6
The need for inhaled phosphodiesterase inhibitors in chronic obstructive pulmonary disease	6
Emerging pharmacological strategies for treating and preventing mpox	6
Coadministration of silymarin with iron chelators in transfusion-dependent β-thalassemia patients: a systematic review and meta-analysis for effect on iron overload	6
Novel pharmacological therapies for the treatment of endometriosis	6
Effects of anti-inflammatory treatment on efficacy of selective laser trabeculoplasty: a systematic review and meta-analysis	6
Dried blood spot sampling for therapeutic drug monitoring: challenges and opportunities	6
Sex and gender differences in the treatment of arterial hypertension	5
Optimization of potassium management in patients with chronic kidney disease and type 2 diabetes on finerenone	5
Anticholinergics and falls in older adults	5
Effect of Wuzhi capsules on cyclosporine A concentration in children with aplastic anemia immunotherapy: a single-center observational study	5
A profile of delafloxacin in the treatment of adults with community-acquired bacterial pneumonia	5
Machine learning, pharmacogenomics, and clinical psychiatry: predicting antidepressant response in patients with major depressive disorder	5
The effect of inhaled corticosteroids on the outcomes of patients with COVID-19: A systematic review and meta-analysis of randomized controlled trials	5
Ribosomopathies and cancer: pharmacological implications	5
The evolution of clinical trials for pediatric pulmonary hypertension: are the needs of patients and their caregivers being met?	5
Individualized precision dosing approaches to optimize antimicrobial therapy in pediatric populations	5
WHO collaborative registration procedure using stringent regulatory authorities’ medicine evaluation: reliance in action?	5
Bridging the gap in cardiovascular care in diabetic patients: are cardioprotective antihyperglycemic agents underutilized?	5
3D printing – an alternative strategy for pediatric medicines	5
Effectiveness of statins in people living with HIV: a systematic review and meta-analysis of randomized controlled trials	5
Comparison of the relative efficacy of different biologics in different body areas in patients with moderate to severe psoriasis receiving biologics and tofacitinib in phase 3 randomized controlled tr	5
Hormonal contraception, past, present, and future part 2: optimizing combined oral contraceptives to decrease risks for healthy women	5
The role of CYP2C19 genotyping to guide antiplatelet therapy following ischemic stroke or transient ischemic attack	5
Vestibular function in children with generalized epilepsy and treated with valproate	5
Psychiatric and non-psychiatric drugs causing false-positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS	5
Systematic reviews of randomized controlled trials of cannabinoid products in chronic pain conditions and for symptoms associated with multiple sclerosis: what do they tell us?	5

Clostridioides difficile resistance to antibiotics, including post-COVID-19 data	5
Pharmacological profile of once-weekly injectable semaglutide for chronic weight management	5
A model based on machine learning for the prediction of cyclosporin A trough concentration in Chinese allo-HSCT patients	5
Correction	5
Edoxaban for the treatment of pulmonary embolism in hospitalized COVID-19 patients	5
Steady-state pharmacokinetics, efficacy, and safety of bictegravir in Chinese patients with HIV: an observational study	5
Centering the patient in decisions about opioid tapering	5
A single inhaler triple therapy fluticasone furoate/umeclidinium/vilanterol for the treatment of COPD	5
Population pharmacokinetics of omeprazole in obese and normal-weight adults	5
Therapeutic approach to neurological manifestations of Angelman syndrome	5
Optimizing ganciclovir and valganciclovir dosing regimens in pediatric patients with cytomegalovirus infection: a spotlight on therapeutic drug monitoring	4
Influence of N -acetyltransferase 2 polymorphisms and clinical variables on liver function profile of tuberculosis patients	4
Biosimilar and generic formulations of novel antidiabetic drugs: the role of liraglutide in clinical pharmacology of type 2 diabetes	4
Correction	4
Perspectives on deprescribing in palliative care	4
The effect of epilepsy and antiseizure medications on cardiac autonomic functions in children with epilepsy	4
Emerging insights and future prospects for therapeutic application of siRNA targeting angiotensinogen in hypertension	4
An update on the clinical pharmacology of kratom: uses, abuse potential, and future considerations	4
Artificial intelligence and machine learning in clinical pharmacological research	4
Efficacy and safety of insulin detemir versus glargine in patients with diabetes: a systematic review and meta-analysis	4
A comprehensive strategy to address shortage of Erwinia asparaginase in pediatric acute lymphoblastic leukemia	4
Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes	4
Therapeutic effects of topical cetirizine in the treatment of female pattern hair loss: a randomized controlled noninferiority trial	4
Scoping review of the availability and uptake of disease modifying therapies in children and adolescents with multiple sclerosis	4
Type of proteinuria might be essential for RAAS-I treatment in children with CAKUT	4
The heterogeneity of metabolic syndrome presentation and challenges this causes in its pharmacological management: a narrative review focusing on principal risk modifiers	4
The search for blood biomarkers useful in treating atopic dermatitis patients	4
Significant predictors for olanzapine pharmacokinetics: a systematic review of population pharmacokinetic studies	4
Updates in the diagnosis and practical management of allergic rhinitis	4
STOPP/START criteria for potentially inappropriate medications/potential prescribing omissions in older people: uptake and clinical impact	4
Therapeutic drug monitoring-guided dosing for pediatric cystic fibrosis patients: recent advances and future outlooks	4
The effect of different levothyroxine administration regimens on thyroid hormone levels: a systematic review, pairwise, and network meta-analysis	4
Artificial intelligence-based model for dose prediction of sertraline in adolescents: a real-world study	4
Snakebite-associated thrombotic microangiopathy: a spotlight on pharmaceutical interventions	4
Renin–angiotensin system inhibition and mortality in patients undergoing dialysis with coronary artery disease: insights from a multi-center observational study	4
Pharmacological approaches to prevent vertical transmission of HIV and HBV	4
The efficacy and toxicity of mirvetuximab soravtansine, a novel antibody-drug conjugate, in the treatment of advanced or recurrent ovarian cancer: a meta-analysis	4
Growing role of SGLT2i in heart failure: evidence from clinical trials	4
A scoping review of the clinical utility of adverse drug reaction causality analysis tools for use in the hospital setting	4
Samidorphan for the treatment of weight gain associated with olanzapine in patients with schizophrenia and bipolar disorder	3
Clinical pharmacology and PK/PD translation of the second-generation Bruton’s tyrosine kinase inhibitor, zanubrutinib	3
Gene therapy in cardiology: pioneering a new era in medical ethics and patient care	3
Analyzing the clinical efficacy and safety of levocetirizine based on its receptor occupancy, intraclass comparison and role in the treatment of CSU: an AROG consensus statement	3
Regional variation in longitudinal trajectories of primary care opioids prescribing across Health Boards in Scotland: a population-based study	3
Novel insights into molecular and cellular aspects of delayed drug hypersensitivity reactions	3
Peroxisome proliferator-activated receptor-gamma (PPARγ) and its immunomodulation function: current understanding and future therapeutic implications	3
The evolving landscape of PARP inhibitors in castration-resistant prostate cancer: a spotlight on treatment combinations	3
Stimulant and hallucinogenic novel psychoactive substances; an update	3
A profile of safety and efficacy of fezolinetant for the treatment of menopausal vasomotor symptoms	3
Clinical considerations when switching antiretroviral therapy	3
Association between myocarditis and antipsychotics other than clozapine: a systematic literature review and a pharmacovigilance study using VigiBase	3
A scoping review of legibility of hand-written prescriptions and drug-orders: the writing on the wall	3
Predicting drug response and toxicity in metastatic colorectal cancer: the role of germline markers	3
Potential approaches using teneligliptin for the treatment of type 2 diabetes mellitus: current status and future prospects	3
Semaglutide and smoking cessation in individuals with type 2 diabetes mellitus: there is no smoke without fire!	3
Set and setting predict psychopathology, wellbeing and meaningfulness of psychedelic experiences: a correlational study	3
Finerenone: a mineralocorticoid receptor antagonist for the treatment of chronic kidney disease associated with type 2 diabetes	3
Impact of COVID-19 pandemic on the prescribing pattern of oral anticoagulants in the English primary care setting: a population-based segmented interrupted time series analysis of over 53 million indi	3
Who is blind in psychedelic research? Letter to the editor regarding: blinding and expectancy confounds in psychedelic randomized controlled trials	3
Efficacy and safety of oliceridine treatment in patients with postoperative pain: a systematic review and meta-analysis of randomized controlled trials	3
A review of recent advances in the treatment of adults with complicated urinary tract infection	3
Comparison of weight loss and adverse events of obesity drugs in children and adolescents: a systematic review and meta-analysis	3
Dual pathway inhibition in patients with atherosclerotic disease: pharmacodynamic considerations and clinical implications	3
JAK inhibitors in vitiligo: what they hit and what they miss - an immunopathogenesis based exposition of existing evidence	3
The era of lenalidomide maintenance therapy in multiple myeloma: settings for achieving best outcomes	3
Pharmacological management of testosterone deficiency in men current advances and future directions	3
Evogliptin for the treatment option for type 2 diabetes: an update of the literature	3
Drug related adverse event assessment in neonates in clinical trials and clinical care	3
COMBINE 2 is better than one: shaping the future of therapeutics in inadequately controlled type 2 diabetes	3
The association between the use of sodium glucose cotransporter 2 inhibitor and the risk of diabetic retinopathy and other eye disorders: a systematic review and meta-analysis	3
Comparative effectiveness and safety of inhaled corticosteroid plus long-acting β 2 -agonist fixed-dose combinations vs. long-acting muscarinic antagonist in bronchi	3
Association between statins’ exposure with incidence and prognosis of gastric cancer: an updated meta‐analysis	3
Letermovir and new horizons in prevention of post-transplant CMV	3
Sodium-glucose co-transporter 2 inhibition and acute myocardial infarction: the DAPA-MI and EMPACT-MI trials	3
Updates in innovation of the treatment of pyoderma gangrenosum	3