Expert Review of Clinical Pharmacology

Article	Citations
Personalizing tamoxifen therapy in adjuvant therapy: a brief summary of the ongoing discussion	57
A review of current and emerging therapies in breast cancer: implications for older adults	56
Renin angiotensin aldosterone inhibitors in the treatment of proteinuria in children with congenital anomalies of the kidney and urinary tract: more evidence needed	41
Prostate cancer and novel pharmacological treatment options–what’s new for 2022?	40
Therapeutic drug monitoring of antiretroviral therapy: current progresses and future directions	40
Sparsentan: a dual endothelin and angiotensin II receptor antagonist approved for IgA nephropathy	39
Reducing the risk of death – a possible outcome in COPD patients	39
Strategies for lowering lipoprotein(a): a spotlight on novel pharmacological treatments	36
A simulation study to assess the influence of population pharmacokinetic model selection on Bayesian forecasting of vancomycin exposure in preterm neonates	35
Practical considerations and emerging approaches for the management of vasomotor and sexual symptoms in breast cancer patients on endocrine therapies	32
Sodium-glucose cotransporter 2 inhibitors in frail, older people with type 2 diabetes and heart failure: do we have enough evidence to confidently support the use?	31
JAK inhibitors in dermatology: the road travelled and path ahead, a narrative review	30
Complement C5 inhibitor crovalimab for the treatment of paroxysmal nocturnal hemoglobinuria	30
Pharmacological and clinical profile of ravulizumab 100 mg/mL formulation for paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome	30
Effects of the augmentation with quetiapine or olanzapine on the metabolism of duloxetine: a retrospective analysis	27
Management of polypharmacy through deprescribing in older patients: a review of the role of AI tools	25
What is the potential for abuse of lisdexamfetamine in adults? A preclinical and clinical literature review and expert opinion	24
Clinical pharmacology of antiplatelet drugs	24
Amylin analogs for the treatment of obesity without diabetes: present and future	23
Risk of new onset diabetes mellitus with pitavastatin as compared to atorvastatin and rosuvastatin: a systematic review and meta-analysis	23
Brimonidine tartrate ophthalmic solution 0.025% for redness relief: an overview of safety and efficacy	22
Clinical efficacy and safety of topical difamilast in the treatment of patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials	22
Cannabidiol drug interaction considerations for prescribers and pharmacists	21
Treatment management for rosacea: current pharmacological and non-pharmacological options	20
Role of tenecteplase in ischemic stroke after 4.5 hours: an evaluation of the TRACE-III trial	20

Profiling the pattern of medication use during pregnancy: an international scoping review of observational studies	19
Medical management of pediatric chronic rhinosinusitis	18
Reply to: The risk for genito-urinary infections with sodium-glucose cotransporter-2 inhibitors: duration rather than dose matter?	18
Broadening access to tenofovir alafenamide for the treatment and prevention of HIV-1 infection	18
Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective	18
The thiazide-like diuretic chlorthalidone as an alternative evidence-based therapy for resistant hypertension in patients with stage 4 chronic kidney disease	17
Nirmatrelvir/Ritonavir and molnupiravir: an update on COVID-19 antivirals in the Omicron era	17
Complications related to oral corticosteroid use in asthma patients: a retrospective cohort study	17
Drug-drug interactions associated with FLT3 inhibitors for acute myeloblastic leukemia: current landscape	16
Intestinal microbiome and epilepsy: a new therapeutic approach?	16
OPTIMA-ID: development and validation of a medicine optimization tool for older adults with intellectual disability	16
Pharmacological strategies for the management of the antisocial personality disorder	16
CYP2C19 genotype-guided dosing of proton pump inhibitors: progress in clinical trials and real-world use	16
Reconsidering molecular pathways in giant benign prostatic hyperplasia: a potential strategy for an unmet challenge	16
Clozapine for older adults with severe mental illness: a systematic review and expert recommendations for clinical practice	15
Population pharmacokinetic modeling and exposure-response analysis of anrikefon: insights and implications in clinical analgesia	15
Recent advances and unmet needs in the treatment of drug-resistant tuberculosis	15
A profile of azetukalner for the treatment of epilepsy: from pharmacology to potential for therapy	15
Could GLP-1RAs improve outcomes for patients with chronic migraine?	15
Association between sodium-glucose cotransporter 2 inhibitors and eye disorders: a systematic review and meta-analysis	15
Pediatric attention deficit hyperactivity disorder (ADHD): 2022 updates on pharmacological management	15
Hydroxyurea in the sickle cell disease modern era	15
Clinical pharmacology of SGLT-2 inhibitors in heart failure	15
Current and emerging pharmacotherapies for treating vascular malformations	14
FLOT vs CROSS in localized esophageal adenocarcinoma: what is the current best strategy?	14
Osteoarthritis and cardiometabolic diseases: shared mechanisms, modifiable risk factors, and integrated management strategies	14
Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic review and meta-analysis	14
A narrative review of non-racemic amisulpride (SEP-4199) for treatment of depressive symptoms in bipolar disorder and LB-102 for treatment of schizophrenia	14
Innovation in pediatric atopic dermatitis care: examining emerging topical treatment options	14
Population pharmacokinetic modeling of piperacillin in critically ill adult patients: consideration of sex-based differences during model development	14
Efficacy and safety of tislelizumab for malignant solid tumor: a systematic review and meta-analysis of phase III randomized trials	13
Phosphatidylinositol 3 kinase inhibitor-related pneumonitis: a systematic review and meta-analysis	13
An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry	13
Early response is a strong predictor of the long-term response in psoriasis patients receiving risankizumab or guselkumab in the real-world: a retrospective analysis	13
Methenamine Hippurate in UTI management: a reemerging pharmacological strategy	13
Progress in the pharmacological management of vasovagal syncope	13
A systematic review and meta-analysis of users versus non-users: unveiling the influence of proton pump inhibitors on capecitabine efficacy in colorectal cancer	13
The nocebo phenomenon in the COVID-19 pandemic: a nocebodemic effect	13
Risk factors for a broken heart: understanding drug-induced causes for Takotsubo syndrome and pharmacological treatment options	13
Pharmacotherapy for previously treated gastric cancer patients: current options and future developments	13
Methotrexate polyglutamates	12
Real-world clinical effectiveness of once-weekly semaglutide in patients with type 2 diabetes: a systematic literature review	12
Physiologically-based pharmacokinetic modeling to predict the exposure and provide dosage regimens of adalimumab in patients with juvenile idiopathic arthritis	12
Shaping future deprescribing priorities: outcomes of a World Café stakeholder workshop	12
Pharmacogenomics – a minor rather than major force in clinical medicine	12
Biosimilars for chronic plaque psoriasis: a 2026 update	12
Emerging pharmacological options in the treatment of idiopathic pulmonary fibrosis (IPF)	11
Designer benzodiazepines: an update	11
PREG-ADR: development and validation of a predictive tool for adverse drug reactions in hospitalized pregnant women	11
Optimization of secukinumab dose regimens in patients with moderate-to-severe plaque psoriasis via exposure-response modeling	11

Pharmacokinetic interaction of quetiapine and lamotrigine – victim and perpetrator?	11
Comparison of dopamine D2 receptor occupancy profiles between risperidone ISM versus oral risperidone and monthly paliperidone palmitate based on population pharmacokinetic modelling and simulations	10
Pharmacology considerations for managing pregnancy in women with systemic lupus erythematosus	10
Interstitial lung disease associated with anti-HER2 anti-body drug conjugates: results from clinical trials and the WHO's pharmacovigilance database	10
Is therapeutic drug monitoring a dancing partner for TNF-α inhibitors in real-world practice? Answers from an updated systematic review and meta-analysis	10
Hormonal contraception, past, present, and future part 1: the early path – facts, stories, and controversies	10
Genito-urinary infectious adverse events related to sodium glucose cotransporter-2 inhibitors: a network meta-analysis and meta-regression	10
Advances in pharmacokinetic-pharmacodynamic modelling for pediatric drug development: extrapolations and exposure-response analyses	10
TYK2 as a novel therapeutic target in psoriasis	10
Clinical pharmacology of siRNA therapeutics: current status and future prospects	10
Golimumab retention in patients with psoriatic arthritis and axial spondyloarthritis: evidence from up to a decade of follow-up	10
Efficacy and safety of dupilumab in chronic rhinosinusitis with nasal polyps: a systematic review and meta-analysis	10
The future of pharmacology education: The Veterinary Educators in Pharmacology Special Interest Group (VEPSIG)	10
Biomarker discovery in acetaminophen hepatotoxicity: leveraging single-cell transcriptomics and mechanistic insight	10
The orexin system and alcohol use disorder: bridging the gap between preclinical and clinical research	10
Signal mining study of severe cutaneous adverse events of valaciclovir or acyclovir based on the FAERS database	10
Encouraging appropriate use of proton pump inhibitors: existing initiatives and proposals for the future	10
Psychedelic drugs for the treatment of substance use disorders	10
Revolutionizing diabetes care: unveiling tirzepatide’s potential in glycemic control and beyond	10
The pharmacotherapeutic options in patients with catecholamine-resistant vasodilatory shock	10
Pharmacological treatment for transforming growth factor beta induced corneal dystrophies: what is the way forward?	9
Clozapine for treatment refractory catatonia in individuals with autism spectrum disorder: a retrospective chart review study	9
Adverse clinical outcomes associated with drug-related hospitalizations in people with dementia	9
Statin-related neurocognitive disorder: a real-world pharmacovigilance study based on the FDA adverse event reporting system	9
Clinical outcomes of oral anticoagulant discontinuation in atrial fibrillation: a systematic review and meta-analysis	9
Availability and evaluation of medication management resources for carers of people with dementia: a scoping review with an environmental scan	9
Practical challenges and considerations in adopting biosimilars in oncology clinical practice within a large healthcare system	9
The systems medicine view of semaglutide: from clinical trials to molecular mechanisms	9
Opioid use disorder in pediatric populations: considerations for perioperative pain management and precision opioid analgesia	9
Predictors of warfarin therapeutic dose across thromboembolic indications: an exploratory early clinical evaluation study using machine learning-integrated explainable artificial intelligence and Baye	9
Current understanding of the etiology of cyclic vomiting syndrome and therapeutic strategies in its management	9
Intravitreal immunotherapy in non-infectious uveitis: an update	9
Effects of single-nucleotide polymorphism on the pharmacokinetics and pharmacodynamics of metformin	8
Detrimental impact of gastric acid suppressants on vascular endothelial growth factor receptor tyrosine kinase inhibitors efficacy: evidence from a systematic review and meta-analysis	8
Next-generation sequencing in pharmacogenomics – fit for clinical decision support?	8
Novel and emerging treatment strategies for lupus nephritis	8
Considerations when prescribing opioid agonist therapies for people living with HIV	8
Optimizing outcomes and managing adverse events in locally advanced or metastatic urothelial cancer: a clinical pharmacology perspective	8
Treatment and prevention of influenza in geriatric patients	8
Perspectives on deprescribing in older people with type 2 diabetes and/or cardiovascular conditions: challenges from healthcare provider, patient and caregiver perspective, and interventions to suppor	8
Genotype-guided pharmacotherapy: the challenges of integrating pharmacogenomic testing into routine healthcare with a focus on experiences at a single site	8
Efficacy and safety of statins for nonalcoholic/metabolic dysfunction-associated fatty liver diseases: a systematic review and meta-analysis	8
Vaping Δ 9 -tetrahydrocannabinol (Δ 9 -THC) in liquid forms: pharmacokinetics, pharmacodynamics, a	8
Closing the gaps in the access to quality-assured medicines for global health: The case for oxytocin for postpartum haemorrhage	7
Dried blood spot sampling for therapeutic drug monitoring: challenges and opportunities	7
A tiered decisional framework for genetic epileptic syndromes with or without encephalopathies: from standard care to investigational strategies	7
The impact of pregnancy-related hormonal and physiological changes on antiseizure medications: expert perspective	7
Factor-VIII mimetic bispecific antibodies for the treatment of hemophilia A: an update	7
The ketamine chameleon: history, pharmacology, and the contested value of experience	7
Novel pharmacological therapies for the treatment of endometriosis	7
The need for inhaled phosphodiesterase inhibitors in chronic obstructive pulmonary disease	7
Quantitative effects of sodium-glucose cotransporter-2 inhibitors on liver functions in patients with nonalcoholic fatty liver disease	7
Implementing pharmacogenetics in clinical trials: considerations about current methodological, ethical, and regulatory challenges	7
The role of glucagon-like peptide-1 receptor agonists in nonalcoholic fatty liver disease	7
Emerging pharmacological strategies for treating and preventing mpox	7
An overview on disease modifying and symptomatic drug treatments for multiple sclerosis	7
The outcomes of considering goals of care in medication reviews for older adults: a systematic review	7
The changes of IgE levels in type 2 inflammatory diseases after treatment of dupilumab: a systematic review and meta-analysis	7
GLP-1 receptor agonist safety in a perioperative setting: more questions than answers	7
Challenges, unmet needs and future directions – a critical evaluation of the clinical trial landscape in schizophrenia research	7
The evolution of clinical trials for pediatric pulmonary hypertension: are the needs of patients and their caregivers being met?	6
Therapeutic drug monitoring for de-escalating anti-tumor necrosis factor therapy in patients with inflammatory bowel disease	6
Vestibular function in children with generalized epilepsy and treated with valproate	6
Chelating anticoagulants reduce plasma doxycycline measurements: implications for doxy PEP monitoring	6
Steady-state pharmacokinetics, efficacy, and safety of bictegravir in Chinese patients with HIV: an observational study	6
Integrating homologous recombination deficiency and replication stress: converging strategies unlocking new frontiers in precision oncology	6
Optimization of potassium management in patients with chronic kidney disease and type 2 diabetes on finerenone	6
Bridging the gap in cardiovascular care in diabetic patients: are cardioprotective antihyperglycemic agents underutilized?	6
Improving evidence-based antiseizure medication prescribing during pregnancy: strengthening research and clinical practice	6
Centering the patient in decisions about opioid tapering	6
Pharmacokinetics, efficacy, and safety of arsenic formulations in acute promyelocytic leukemia treatment	6
A model based on machine learning for the prediction of cyclosporin A trough concentration in Chinese allo-HSCT patients	6
Effectiveness of statins in people living with HIV: a systematic review and meta-analysis of randomized controlled trials	6
Clostridioides difficile resistance to antibiotics, including post-COVID-19 data	6
Machine learning, pharmacogenomics, and clinical psychiatry: predicting antidepressant response in patients with major depressive disorder	6
Correction	6
Sex and gender differences in the treatment of arterial hypertension	6
Drug–drug interactions in targeted cancer therapies: a focus on tyrosine kinase inhibitors	6
Traumatic brain injury. Rethinking pharmacological clinical trials in an orphan pathology	6
Optimizing anticholinergic use in urology: strategies for safe prescribing amidst polypharmacy	6

3D printing – an alternative strategy for pediatric medicines	6
Prescribing pattern of disease-modifying antirheumatic drugs in Scotland (2019–2023): a population-based retrospective cohort study	6
Correction	6
The heterogeneity of metabolic syndrome presentation and challenges this causes in its pharmacological management: a narrative review focusing on principal risk modifiers	5
The effect of different levothyroxine administration regimens on thyroid hormone levels: a systematic review, pairwise, and network meta-analysis	5
Snakebite-associated thrombotic microangiopathy: a spotlight on pharmaceutical interventions	5
Scoping review of the availability and uptake of disease modifying therapies in children and adolescents with multiple sclerosis	5
Optimizing ganciclovir and valganciclovir dosing regimens in pediatric patients with cytomegalovirus infection: a spotlight on therapeutic drug monitoring	5
Semaglutide for the treatment of MASH: reaching into the ESSENCE of cardio-metabolic health?	5
A comprehensive strategy to address shortage of Erwinia asparaginase in pediatric acute lymphoblastic leukemia	5
Obese and overweight patients with type 2 diabetes mellitus are not treated optimally - an overview of current clinical practice and future perspectives	5
Correction	5
Potential beneficial effect of treatment with PCSK9 inhibitors on vascular endothelial dysfunction: a systematic review and meta-analysis	5
An update on the clinical pharmacology of kratom: uses, abuse potential, and future considerations	5
Updates in the diagnosis and practical management of allergic rhinitis	5
Therapeutic drug monitoring-guided dosing for pediatric cystic fibrosis patients: recent advances and future outlooks	5
Perspectives on deprescribing in palliative care	5
Renin–angiotensin system inhibition and mortality in patients undergoing dialysis with coronary artery disease: insights from a multi-center observational study	5
A comprehensive systematic review of the types of medication classes targeted by deprescribing tools and the tools/interventions applied to each class	5
Influence of N -acetyltransferase 2 polymorphisms and clinical variables on liver function profile of tuberculosis patients	5
Emerging insights and future prospects for therapeutic application of siRNA targeting angiotensinogen in hypertension	5
Psychiatric and non-psychiatric drugs causing false-positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS	5
Significant predictors for olanzapine pharmacokinetics: a systematic review of population pharmacokinetic studies	5
Pharmacovigilance in the field of addiction: challenges and emerging solutions	5
Artificial intelligence and machine learning in clinical pharmacological research	5
Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes	5
STOPP/START criteria for potentially inappropriate medications/potential prescribing omissions in older people: uptake and clinical impact	5
Hormonal contraception, past, present, and future part 2: optimizing combined oral contraceptives to decrease risks for healthy women	5
PD-1/PD-L1 for prostate cancer: from clinical trials to practice	4
The search for blood biomarkers useful in treating atopic dermatitis patients	4
Correction	4
The evolving landscape of PARP inhibitors in castration-resistant prostate cancer: a spotlight on treatment combinations	4
Drug related adverse event assessment in neonates in clinical trials and clinical care	4
Impact of COVID-19 pandemic on the prescribing pattern of oral anticoagulants in the English primary care setting: a population-based segmented interrupted time series analysis of over 53 million indi	4
Type of proteinuria might be essential for RAAS-I treatment in children with CAKUT	4
Artificial intelligence-based model for dose prediction of sertraline in adolescents: a real-world study	4
The efficacy and toxicity of mirvetuximab soravtansine, a novel antibody-drug conjugate, in the treatment of advanced or recurrent ovarian cancer: a meta-analysis	4
Considerations for the treatment of older adults with chronic lymphocytic leukemia	4
Prophylaxis for inherited factor X deficiency: a systematic review	4
Set and setting predict psychopathology, wellbeing and meaningfulness of psychedelic experiences: a correlational study	4
Therapeutic effects of topical cetirizine in the treatment of female pattern hair loss: a randomized controlled noninferiority trial	4
Comparative effectiveness and safety of inhaled corticosteroid plus long-acting β 2 -agonist fixed-dose combinations vs. long-acting muscarinic antag	4
The effect of epilepsy and antiseizure medications on cardiac autonomic functions in children with epilepsy	4
A scoping review of the clinical utility of adverse drug reaction causality analysis tools for use in the hospital setting	4
Novel insights into molecular and cellular aspects of delayed drug hypersensitivity reactions	4
Efficacy and safety of oliceridine treatment in patients with postoperative pain: a systematic review and meta-analysis of randomized controlled trials	4
Stimulant and hallucinogenic novel psychoactive substances; an update	4
Factors to consider when designing clinical trials for repurposed drugs	3
Dual pathway inhibition in patients with atherosclerotic disease: pharmacodynamic considerations and clinical implications	3
A scoping review of legibility of hand-written prescriptions and drug-orders: the writing on the wall	3
Dual incretin agonism and the gut microbiome: does the heart of metabolic regulation beat in the gut?	3
Updates in innovation of the treatment of pyoderma gangrenosum	3
Pharmacological interventions for alcohol use disorder: novel insights from recent clinical trials	3
Current status of biological therapy use for older adults with severe asthma	3
Impact of gabapentinoids’ reclassification policy and COVID-19 on gabapentinoids’ utilization pattern and their associated mortality in Scotland and Northern Ireland: a segmental regression analysis	3
Clinical considerations when switching antiretroviral therapy	3
A review of recent advances in the treatment of adults with complicated urinary tract infection	3
Is ranitidine necessary as premedication for regimens containing paclitaxel? A non-inferiority study	3
Effect of terlipressin on renal outcomes in patients with liver cirrhosis and ascites: a retrospective multicenter study	3
Gene therapy in cardiology: pioneering a new era in medical ethics and patient care	3
Brexpiprazole for anxiety symptoms in people living with schizophrenia: a plain language summary	3
COMBINE 2 is better than one: shaping the future of therapeutics in inadequately controlled type 2 diabetes	3
Potential approaches using teneligliptin for the treatment of type 2 diabetes mellitus: current status and future prospects	3
Letermovir and new horizons in prevention of post-transplant CMV	3
Pharmacological management of testosterone deficiency in men current advances and future directions	3
Comparison of weight loss and adverse events of obesity drugs in children and adolescents: a systematic review and meta-analysis	3
The outcomes of goal-oriented medication reviews for the elderly: current research and future directions	3
JAK inhibitors in vitiligo: what they hit and what they miss - an immunopathogenesis based exposition of existing evidence	3
Therapeutic drug monitoring of Janus kinase inhibitors for precision dosing: where do we stand ?	3
Samidorphan for the treatment of weight gain associated with olanzapine in patients with schizophrenia and bipolar disorder	3
A profile of safety and efficacy of fezolinetant for the treatment of menopausal vasomotor symptoms	3
Rethinking anticholinergic burden in older adults: innovative approaches to detection and management	3
Semaglutide and smoking cessation in individuals with type 2 diabetes mellitus: there is no smoke without fire!	3
Association between statins’ exposure with incidence and prognosis of gastric cancer: an updated meta‐analysis	3
Analyzing the clinical efficacy and safety of levocetirizine based on its receptor occupancy, intraclass comparison and role in the treatment of CSU: an AROG consensus statement	3
Sodium-glucose co-transporter 2 inhibition and acute myocardial infarction: the DAPA-MI and EMPACT-MI trials	3
N-methyl-D-aspartate receptor as a therapeutic target for burning mouth syndrome	3
Response to letter to the editor: therapeutic importance of proteinuria classification in children with congenital anomalies of the kidney and urinary tract	3
An update on the treatment paradigm for non-clear cell renal cell carcinoma	3