Expert Review of Clinical Pharmacology

Article	Citations
Strategies for lowering lipoprotein(a): a spotlight on novel pharmacological treatments	66
Personalizing tamoxifen therapy in adjuvant therapy: a brief summary of the ongoing discussion	44
Renin angiotensin aldosterone inhibitors in the treatment of proteinuria in children with congenital anomalies of the kidney and urinary tract: more evidence needed	40
Reducing the risk of death – a possible outcome in COPD patients	36
Why is diagnosis, investigation, and improved management of kidney stone disease important? Non-pharmacological and pharmacological treatments for nephrolithiasis	32
Therapeutic drug monitoring of antiretroviral therapy: current progresses and future directions	32
Clinical pharmacology of antiplatelet drugs	32
Sodium-glucose cotransporter 2 inhibitors in frail, older people with type 2 diabetes and heart failure: do we have enough evidence to confidently support the use?	32
Risk of new onset diabetes mellitus with pitavastatin as compared to atorvastatin and rosuvastatin: a systematic review and meta-analysis	31
Prostate cancer and novel pharmacological treatment options–what’s new for 2022?	30
Effects of the augmentation with quetiapine or olanzapine on the metabolism of duloxetine: a retrospective analysis	30
Pharmacological and clinical profile of ravulizumab 100 mg/mL formulation for paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome	27
Management of polypharmacy through deprescribing in older patients: a review of the role of AI tools	27
A review of current and emerging therapies in breast cancer: implications for older adults	26
Practical considerations and emerging approaches for the management of vasomotor and sexual symptoms in breast cancer patients on endocrine therapies	25
What is the potential for abuse of lisdexamfetamine in adults? A preclinical and clinical literature review and expert opinion	25
Sparsentan: a dual endothelin and angiotensin II receptor antagonist approved for IgA nephropathy	25
JAK inhibitors in dermatology: the road travelled and path ahead, a narrative review	25
Amylin analogs for the treatment of obesity without diabetes: present and future	23
Fetal safety of medications used in treating infertility	23
Role of tenecteplase in ischemic stroke after 4.5 hours: an evaluation of the TRACE-III trial	22
Clinical efficacy and safety of topical difamilast in the treatment of patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials	22
Broadening access to tenofovir alafenamide for the treatment and prevention of HIV-1 infection	21
Treatment management for rosacea: current pharmacological and non-pharmacological options	21
Brimonidine tartrate ophthalmic solution 0.025% for redness relief: an overview of safety and efficacy	21

The pharmacotherapeutics of sarcoidosis	19
Cannabidiol drug interaction considerations for prescribers and pharmacists	19
Dostarlimab for the treatment of advanced endometrial cancer	19
The thiazide-like diuretic chlorthalidone as an alternative evidence-based therapy for resistant hypertension in patients with stage 4 chronic kidney disease	18
Reply to: The risk for genito-urinary infections with sodium-glucose cotransporter-2 inhibitors: duration rather than dose matter?	18
Complications related to oral corticosteroid use in asthma patients: a retrospective cohort study	18
Pharmacogenetics-based population pharmacokinetic analysis for dose optimization of ritonavir-boosted atazanavir in Thai adult HIV-infected patients	17
Recent pharmacological approaches for the treatment of renal cell carcinoma	17
Nirmatrelvir/Ritonavir and molnupiravir: an update on COVID-19 antivirals in the Omicron era	16
Intestinal microbiome and epilepsy: a new therapeutic approach?	16
Pharmacological strategies for the management of the antisocial personality disorder	16
OPTIMA-ID: development and validation of a medicine optimization tool for older adults with intellectual disability	15
Nicotine e-cigarettes for smoking cessation: a clinical pharmacology perspective	15
Melflufen for the treatment of multiple myeloma	15
Voclosporin: a novel calcineurin inhibitor for the treatment of lupus nephritis	15
Pediatric attention deficit hyperactivity disorder (ADHD): 2022 updates on pharmacological management	15
Effect of laparoscopic sleeve gastrectomy on drug pharmacokinetics	14
Population pharmacokinetic modeling and exposure-response analysis of anrikefon: insights and implications in clinical analgesia	14
A profile of azetukalner for the treatment of epilepsy: from pharmacology to potential for therapy	14
Association between sodium-glucose cotransporter 2 inhibitors and eye disorders: a systematic review and meta-analysis	13
Clozapine for older adults with severe mental illness: a systematic review and expert recommendations for clinical practice	13
Drug-drug interactions associated with FLT3 inhibitors for acute myeloblastic leukemia: current landscape	13
Hydroxyurea in the sickle cell disease modern era	13
Current status and prospects of IL-6–targeting therapy	13
FLOT vs CROSS in localized esophageal adenocarcinoma: what is the current best strategy?	12
A narrative review of non-racemic amisulpride (SEP-4199) for treatment of depressive symptoms in bipolar disorder and LB-102 for treatment of schizophrenia	12
Clinical pharmacology of SGLT-2 inhibitors in heart failure	12
Real-world clinical effectiveness of once-weekly semaglutide in patients with type 2 diabetes: a systematic literature review	12
Early response is a strong predictor of the long-term response in psoriasis patients receiving risankizumab or guselkumab in the real-world: a retrospective analysis	12
Methenamine Hippurate in UTI management: a reemerging pharmacological strategy	12
Methotrexate polyglutamates	12
Antimicrobial safety considerations in critically ill patients: part II: focused on anti-microbial toxicities	11
Pharmacotherapy for previously treated gastric cancer patients: current options and future developments	11
Efficacy and safety of tislelizumab for malignant solid tumor: a systematic review and meta-analysis of phase III randomized trials	11
Risk factors for a broken heart: understanding drug-induced causes for Takotsubo syndrome and pharmacological treatment options	11
Pharmacogenomics – a minor rather than major force in clinical medicine	11
Emerging pharmacological options in the treatment of idiopathic pulmonary fibrosis (IPF)	11
Physiologically-based pharmacokinetic modeling to predict the exposure and provide dosage regimens of adalimumab in patients with juvenile idiopathic arthritis	11
The nocebo phenomenon in the COVID-19 pandemic: a nocebodemic effect	11
Designer benzodiazepines: an update	11
An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry	11
Revisiting the association between sodium-glucose cotransporter-2 inhibitors and the risk of neoplasm in patients with type 2 diabetes: new insights from an updated systematic review and meta-analysis	11
A systematic review and meta-analysis of users versus non-users: unveiling the influence of proton pump inhibitors on capecitabine efficacy in colorectal cancer	11
Encouraging appropriate use of proton pump inhibitors: existing initiatives and proposals for the future	10
Is therapeutic drug monitoring a dancing partner for TNF-α inhibitors in real-world practice? Answers from an updated systematic review and meta-analysis	10
Genito-urinary infectious adverse events related to sodium glucose cotransporter-2 inhibitors: a network meta-analysis and meta-regression	10
Phosphatidylinositol 3 kinase inhibitor-related pneumonitis: a systematic review and meta-analysis	10
Optimization of secukinumab dose regimens in patients with moderate-to-severe plaque psoriasis via exposure-response modeling	10
Signal mining study of severe cutaneous adverse events of valaciclovir or acyclovir based on the FAERS database	10
TYK2 as a novel therapeutic target in psoriasis	10

Revolutionizing diabetes care: unveiling tirzepatide’s potential in glycemic control and beyond	10
Efficacy and safety of dupilumab in chronic rhinosinusitis with nasal polyps: a systematic review and meta-analysis	10
Golimumab retention in patients with psoriatic arthritis and axial spondyloarthritis: evidence from up to a decade of follow-up	10
Pharmacokinetic interaction of quetiapine and lamotrigine – victim and perpetrator?	10
Gender differences in new hypoglycemic drug effects on renal outcomes: a systematic review	9
Biomarker discovery in acetaminophen hepatotoxicity: leveraging single-cell transcriptomics and mechanistic insight	9
Clozapine for treatment refractory catatonia in individuals with autism spectrum disorder: a retrospective chart review study	9
Pharmacological and safety profile of a prolonged-release lanreotide formulation in acromegaly	9
Interstitial lung disease associated with anti-HER2 anti-body drug conjugates: results from clinical trials and the WHO's pharmacovigilance database	9
Psychedelic drugs for the treatment of substance use disorders	9
Clinical pharmacology of siRNA therapeutics: current status and future prospects	9
Hormonal contraception, past, present, and future part 1: the early path – facts, stories, and controversies	9
Dasiglucagon for treating severe hypoglycemia in patients with diabetes	9
Practical challenges and considerations in adopting biosimilars in oncology clinical practice within a large healthcare system	8
The future of pharmacology education: The Veterinary Educators in Pharmacology Special Interest Group (VEPSIG)	8
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause	8
Reliance is key to effective access and oversight of medical products in case of public health emergencies	8
Advances in pharmacokinetic-pharmacodynamic modelling for pediatric drug development: extrapolations and exposure-response analyses	8
Adverse clinical outcomes associated with drug-related hospitalizations in people with dementia	8
Clinical outcomes of oral anticoagulant discontinuation in atrial fibrillation: a systematic review and meta-analysis	8
The pharmacotherapeutic options in patients with catecholamine-resistant vasodilatory shock	8
Current understanding of the etiology of cyclic vomiting syndrome and therapeutic strategies in its management	8
Antimicrobial safety considerations in critically ill patients: part I: focused on acute kidney injury	8
Opioid use disorder in pediatric populations: considerations for perioperative pain management and precision opioid analgesia	8
Pharmacological treatment for transforming growth factor beta induced corneal dystrophies: what is the way forward?	8
Statin-related neurocognitive disorder: a real-world pharmacovigilance study based on the FDA adverse event reporting system	8
Keeping up with venetoclax for leukemic malignancies: key findings, optimal regimens, and clinical considerations	8
Treatment and prevention of influenza in geriatric patients	7
The impact of pregnancy-related hormonal and physiological changes on antiseizure medications: expert perspective	7
Effects of single-nucleotide polymorphism on the pharmacokinetics and pharmacodynamics of metformin	7
Comparing the renal outcomes in patients with atrial fibrillation receiving different oral anticoagulants	7
Pharmacology considerations for managing pregnancy in women with systemic lupus erythematosus	7
Intravitreal immunotherapy in non-infectious uveitis: an update	7
Impact of SGLT2 inhibitors on the kidney in people with type 2 diabetes and severely increased albuminuria	7
Implementing pharmacogenetics in clinical trials: considerations about current methodological, ethical, and regulatory challenges	7
Novel and emerging treatment strategies for lupus nephritis	7
Quantitative effects of sodium-glucose cotransporter-2 inhibitors on liver functions in patients with nonalcoholic fatty liver disease	7
Detrimental impact of gastric acid suppressants on vascular endothelial growth factor receptor tyrosine kinase inhibitors efficacy: evidence from a systematic review and meta-analysis	7
Intraperitoneal therapy for gastric cancer peritoneal carcinomatosis	7
The orexin system and alcohol use disorder: bridging the gap between preclinical and clinical research	7
Perspectives on deprescribing in older people with type 2 diabetes and/or cardiovascular conditions: challenges from healthcare provider, patient and caregiver perspective, and interventions to suppor	7
The changes of IgE levels in type 2 inflammatory diseases after treatment of dupilumab: a systematic review and meta-analysis	7
Next-generation sequencing in pharmacogenomics – fit for clinical decision support?	7
Biosimilar development and review process in the BRICS-TM countries: Proposal for a standardized model to improve regulatory performance	7
Considerations when prescribing opioid agonist therapies for people living with HIV	7
Availability and evaluation of medication management resources for carers of people with dementia: a scoping review with an environmental scan	7
Genotype-guided pharmacotherapy: the challenges of integrating pharmacogenomic testing into routine healthcare with a focus on experiences at a single site	7
Optimizing outcomes and managing adverse events in locally advanced or metastatic urothelial cancer: a clinical pharmacology perspective	7
Extending the ambit of SGLT2 inhibitors beyond diabetes: a review of clinical and preclinical studies on non-diabetic kidney disease	7
Emerging pharmacological strategies for treating and preventing mpox	6
Closing the gaps in the access to quality-assured medicines for global health: The case for oxytocin for postpartum haemorrhage	6
An overview on disease modifying and symptomatic drug treatments for multiple sclerosis	6
Therapeutic approach to neurological manifestations of Angelman syndrome	6
Population pharmacokinetics of omeprazole in obese and normal-weight adults	6
The outcomes of considering goals of care in medication reviews for older adults: a systematic review	6
The ketamine chameleon: history, pharmacology, and the contested value of experience	6
The need for inhaled phosphodiesterase inhibitors in chronic obstructive pulmonary disease	6
Systematic reviews of randomized controlled trials of cannabinoid products in chronic pain conditions and for symptoms associated with multiple sclerosis: what do they tell us?	6
Sex and gender differences in the treatment of arterial hypertension	6
Novel pharmacological therapies for the treatment of endometriosis	6
Challenges, unmet needs and future directions – a critical evaluation of the clinical trial landscape in schizophrenia research	6
Dried blood spot sampling for therapeutic drug monitoring: challenges and opportunities	6
Correction	6
The role of glucagon-like peptide-1 receptor agonists in nonalcoholic fatty liver disease	6
Ribosomopathies and cancer: pharmacological implications	5
The effect of inhaled corticosteroids on the outcomes of patients with COVID-19: A systematic review and meta-analysis of randomized controlled trials	5
Centering the patient in decisions about opioid tapering	5
The evolution of clinical trials for pediatric pulmonary hypertension: are the needs of patients and their caregivers being met?	5
Bridging the gap in cardiovascular care in diabetic patients: are cardioprotective antihyperglycemic agents underutilized?	5
Correction	5
Significant predictors for olanzapine pharmacokinetics: a systematic review of population pharmacokinetic studies	5
A profile of delafloxacin in the treatment of adults with community-acquired bacterial pneumonia	5
Steady-state pharmacokinetics, efficacy, and safety of bictegravir in Chinese patients with HIV: an observational study	5
Effect of Wuzhi capsules on cyclosporine A concentration in children with aplastic anemia immunotherapy: a single-center observational study	5
Clostridioides difficile resistance to antibiotics, including post-COVID-19 data	5
Vestibular function in children with generalized epilepsy and treated with valproate	5
Optimization of potassium management in patients with chronic kidney disease and type 2 diabetes on finerenone	5
Prescribing pattern of disease-modifying antirheumatic drugs in Scotland (2019–2023): a population-based retrospective cohort study	5
Machine learning, pharmacogenomics, and clinical psychiatry: predicting antidepressant response in patients with major depressive disorder	5
3D printing – an alternative strategy for pediatric medicines	5

The role of CYP2C19 genotyping to guide antiplatelet therapy following ischemic stroke or transient ischemic attack	5
Psychiatric and non-psychiatric drugs causing false-positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS	5
Emerging insights and future prospects for therapeutic application of siRNA targeting angiotensinogen in hypertension	5
Hormonal contraception, past, present, and future part 2: optimizing combined oral contraceptives to decrease risks for healthy women	5
Comparison of the relative efficacy of different biologics in different body areas in patients with moderate to severe psoriasis receiving biologics and tofacitinib in phase 3 randomized controlled tr	5
Anticholinergics and falls in older adults	5
A single inhaler triple therapy fluticasone furoate/umeclidinium/vilanterol for the treatment of COPD	5
Traumatic brain injury. Rethinking pharmacological clinical trials in an orphan pathology	5
A model based on machine learning for the prediction of cyclosporin A trough concentration in Chinese allo-HSCT patients	5
WHO collaborative registration procedure using stringent regulatory authorities’ medicine evaluation: reliance in action?	5
The heterogeneity of metabolic syndrome presentation and challenges this causes in its pharmacological management: a narrative review focusing on principal risk modifiers	5
STOPP/START criteria for potentially inappropriate medications/potential prescribing omissions in older people: uptake and clinical impact	5
Pharmacological profile of once-weekly injectable semaglutide for chronic weight management	5
Pharmacological approaches to prevent vertical transmission of HIV and HBV	5
Effectiveness of statins in people living with HIV: a systematic review and meta-analysis of randomized controlled trials	5
The efficacy and toxicity of mirvetuximab soravtansine, a novel antibody-drug conjugate, in the treatment of advanced or recurrent ovarian cancer: a meta-analysis	4
Therapeutic drug monitoring-guided dosing for pediatric cystic fibrosis patients: recent advances and future outlooks	4
Renin–angiotensin system inhibition and mortality in patients undergoing dialysis with coronary artery disease: insights from a multi-center observational study	4
Growing role of SGLT2i in heart failure: evidence from clinical trials	4
The effect of different levothyroxine administration regimens on thyroid hormone levels: a systematic review, pairwise, and network meta-analysis	4
Scoping review of the availability and uptake of disease modifying therapies in children and adolescents with multiple sclerosis	4
Artificial intelligence and machine learning in clinical pharmacological research	4
The evolving landscape of PARP inhibitors in castration-resistant prostate cancer: a spotlight on treatment combinations	4
Comparative effectiveness and safety of inhaled corticosteroid plus long-acting β 2 -agonist fixed-dose combinations vs. long-acting muscarinic antagonist in bronchi	4
Stimulant and hallucinogenic novel psychoactive substances; an update	4
Artificial intelligence-based model for dose prediction of sertraline in adolescents: a real-world study	4
Influence of N -acetyltransferase 2 polymorphisms and clinical variables on liver function profile of tuberculosis patients	4
Snakebite-associated thrombotic microangiopathy: a spotlight on pharmaceutical interventions	4
An update on the clinical pharmacology of kratom: uses, abuse potential, and future considerations	4
A comprehensive strategy to address shortage of Erwinia asparaginase in pediatric acute lymphoblastic leukemia	4
Optimizing ganciclovir and valganciclovir dosing regimens in pediatric patients with cytomegalovirus infection: a spotlight on therapeutic drug monitoring	4
Updates in the diagnosis and practical management of allergic rhinitis	4
The effect of epilepsy and antiseizure medications on cardiac autonomic functions in children with epilepsy	4
The search for blood biomarkers useful in treating atopic dermatitis patients	4
Therapeutic effects of topical cetirizine in the treatment of female pattern hair loss: a randomized controlled noninferiority trial	4
Correction	4
Efficacy and safety of insulin detemir versus glargine in patients with diabetes: a systematic review and meta-analysis	4
Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes	4
Perspectives on deprescribing in palliative care	4
Biosimilar and generic formulations of novel antidiabetic drugs: the role of liraglutide in clinical pharmacology of type 2 diabetes	4
Semaglutide for the treatment of MASH: reaching into the ESSENCE of cardio-metabolic health?	4
Novel insights into molecular and cellular aspects of delayed drug hypersensitivity reactions	4
A scoping review of the clinical utility of adverse drug reaction causality analysis tools for use in the hospital setting	4
Type of proteinuria might be essential for RAAS-I treatment in children with CAKUT	4
Potential approaches using teneligliptin for the treatment of type 2 diabetes mellitus: current status and future prospects	3
The association between the use of sodium glucose cotransporter 2 inhibitor and the risk of diabetic retinopathy and other eye disorders: a systematic review and meta-analysis	3
Current status of biological therapy use for older adults with severe asthma	3
Peroxisome proliferator-activated receptor-gamma (PPARγ) and its immunomodulation function: current understanding and future therapeutic implications	3
Efficacy and safety of oliceridine treatment in patients with postoperative pain: a systematic review and meta-analysis of randomized controlled trials	3
Evogliptin for the treatment option for type 2 diabetes: an update of the literature	3
Therapeutic drug monitoring of Janus kinase inhibitors for precision dosing: where do we stand ?	3
Dual pathway inhibition in patients with atherosclerotic disease: pharmacodynamic considerations and clinical implications	3
Response to letter to the editor: therapeutic importance of proteinuria classification in children with congenital anomalies of the kidney and urinary tract	3
Updates in innovation of the treatment of pyoderma gangrenosum	3
COMBINE 2 is better than one: shaping the future of therapeutics in inadequately controlled type 2 diabetes	3
The era of lenalidomide maintenance therapy in multiple myeloma: settings for achieving best outcomes	3
Semaglutide and smoking cessation in individuals with type 2 diabetes mellitus: there is no smoke without fire!	3
Drug related adverse event assessment in neonates in clinical trials and clinical care	3
Finerenone: a mineralocorticoid receptor antagonist for the treatment of chronic kidney disease associated with type 2 diabetes	3
Considerations for the treatment of older adults with chronic lymphocytic leukemia	3
Pharmacological management of testosterone deficiency in men current advances and future directions	3
Is ranitidine necessary as premedication for regimens containing paclitaxel? A non-inferiority study	3
Samidorphan for the treatment of weight gain associated with olanzapine in patients with schizophrenia and bipolar disorder	3
A scoping review of legibility of hand-written prescriptions and drug-orders: the writing on the wall	3
A review of recent advances in the treatment of adults with complicated urinary tract infection	3
Analyzing the clinical efficacy and safety of levocetirizine based on its receptor occupancy, intraclass comparison and role in the treatment of CSU: an AROG consensus statement	3
Predicting drug response and toxicity in metastatic colorectal cancer: the role of germline markers	3
A profile of safety and efficacy of fezolinetant for the treatment of menopausal vasomotor symptoms	3
Regional variation in longitudinal trajectories of primary care opioids prescribing across Health Boards in Scotland: a population-based study	3
Rethinking anticholinergic burden in older adults: innovative approaches to detection and management	3
Impact of COVID-19 pandemic on the prescribing pattern of oral anticoagulants in the English primary care setting: a population-based segmented interrupted time series analysis of over 53 million indi	3
Set and setting predict psychopathology, wellbeing and meaningfulness of psychedelic experiences: a correlational study	3
Association between statins’ exposure with incidence and prognosis of gastric cancer: an updated meta‐analysis	3
Dual incretin agonism and the gut microbiome: does the heart of metabolic regulation beat in the gut?	3
Comparison of weight loss and adverse events of obesity drugs in children and adolescents: a systematic review and meta-analysis	3
Association between myocarditis and antipsychotics other than clozapine: a systematic literature review and a pharmacovigilance study using VigiBase	3
Sodium-glucose co-transporter 2 inhibition and acute myocardial infarction: the DAPA-MI and EMPACT-MI trials	3
JAK inhibitors in vitiligo: what they hit and what they miss - an immunopathogenesis based exposition of existing evidence	3
Letermovir and new horizons in prevention of post-transplant CMV	3
Gene therapy in cardiology: pioneering a new era in medical ethics and patient care	3