OOIR: Observatory of International Research

Papers

(The TQCC of Expert Review of Clinical Pharmacology is 7. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
The pharmacotherapeutic options in patients with catecholamine-resistant vasodilatory shock	186
Safety assessment of propranolol for infantile hemangioma: a study in an Asian population	165
Dasiglucagon for treating severe hypoglycemia in patients with diabetes	53
Regional variation in longitudinal trajectories of primary care opioids prescribing across Health Boards in Scotland: a population-based study	42
The continuum of care of anticancer treatment-induced hypothyroidism in patients with solid non-thyroid tumors: time for an intimate collaboration between oncologists and endocrinologists	42
Effectiveness and safety of thiopurines in inflammatory bowel disease patients with NUDT15 polymorphism: a real-world retrospective study	40
Clinical pharmacology of antiplatelet drugs	39
Tocilizumab for the treatment of non‐critical COVID‐19 pneumonia: an overview of the rationale and clinical evidence to date	39
Exploring the room for repurposed hydroxychloroquine to impede COVID-19: toxicities and multipronged combination approaches with pharmaceutical insights	35
Pharmacological and clinical profile of ravulizumab 100 mg/mL formulation for paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome	33
Efficacy and safety of liraglutide for obesity and people who are overweight: a systematic review and meta-analysis of randomized controlled trials	29
Telmisartan (and/or nitrosamine) - induced occult melanoma: first reported case in world literature	29
Comparison of the relative efficacy of different biologics in different body areas in patients with moderate to severe psoriasis receiving biologics and tofacitinib in phase 3 randomized controlled tr	29
The use of oral GnRH antagonists to inhibit the LH surge in women undergoing ovarian stimulation for in vitro fertilization	27
Strategies for lowering lipoprotein(a): a spotlight on novel pharmacological treatments	27
Risk of new onset diabetes mellitus with pitavastatin as compared to atorvastatin and rosuvastatin: a systematic review and meta-analysis	27
Immune checkpoint inhibition of metastatic melanoma: achieving high efficacy in the face of high toxicity	26
Sodium-glucose co-transporter 2 inhibition and acute myocardial infarction: the DAPA-MI and EMPACT-MI trials	26
Reliance is key to effective access and oversight of medical products in case of public health emergencies	25
Comparison of weight loss and adverse events of obesity drugs in children and adolescents: a systematic review and meta-analysis	24
The heterogeneity of metabolic syndrome presentation and challenges this causes in its pharmacological management: a narrative review focusing on principal risk modifiers	23
Antimicrobial safety considerations in critically ill patients: part I: focused on acute kidney injury	22
Effectiveness of statins in people living with HIV: a systematic review and meta-analysis of randomized controlled trials	21
A review of recent advances in the treatment of adults with complicated urinary tract infection	21
JAK inhibitors in vitiligo: what they hit and what they miss - an immunopathogenesis based exposition of existing evidence	20

Determinants of adherence to treatment in patients with ophthalmic conditions	19
Advances in pharmacokinetic-pharmacodynamic modelling for pediatric drug development: extrapolations and exposure-response analyses	19
Renin angiotensin aldosterone inhibitors in the treatment of proteinuria in children with congenital anomalies of the kidney and urinary tract: more evidence needed	18
Samidorphan for the treatment of weight gain associated with olanzapine in patients with schizophrenia and bipolar disorder	18
Adverse clinical outcomes associated with drug-related hospitalizations in people with dementia	18
Clinical outcomes of oral anticoagulant discontinuation in atrial fibrillation: a systematic review and meta-analysis	17
Comparing immunotherapies to other frequently used treatments of gastric cancer	17
Sodium-glucose cotransporter 2 inhibitors in frail, older people with type 2 diabetes and heart failure: do we have enough evidence to confidently support the use?	17
Pharmacological treatment for transforming growth factor beta induced corneal dystrophies: what is the way forward?	16
Past, present, and future of FGFR inhibitors in cholangiocarcinoma: from biological mechanisms to clinical applications	16
Opioid epidemic: lessons learned and updated recommendations for misuse involving prescription versus non-prescription opioids	16
Biologics and small molecules in the management of psoriatic arthritis: Reproduction related issues in female and male patients	16
A scoping review of legibility of hand-written prescriptions and drug-orders: the writing on the wall	15
Gene therapy in cardiology: pioneering a new era in medical ethics and patient care	15
Psychiatric and non-psychiatric drugs causing false-positive amphetamines urine test in psychiatric patients: a pharmacovigilance analysis using FAERS	15
Updates in innovation of the treatment of pyoderma gangrenosum	15
Personalizing tamoxifen therapy in adjuvant therapy: a brief summary of the ongoing discussion	14
The era of lenalidomide maintenance therapy in multiple myeloma: settings for achieving best outcomes	14
Prostate cancer and novel pharmacological treatment options–what’s new for 2022?	14
Availability and evaluation of medication management resources for carers of people with dementia: a scoping review with an environmental scan	14
Pharmacological approaches to prevent vertical transmission of HIV and HBV	14
Keeping up with venetoclax for leukemic malignancies: key findings, optimal regimens, and clinical considerations	13
Sotagliflozin and decompensated heart failure: results of the SOLOIST-WHF trial	13
Inhaler technique in asthma and COPD: challenges and unmet knowledge that can contribute to suboptimal use in real life	13
Opioid use disorder in pediatric populations: considerations for perioperative pain management and precision opioid analgesia	13
Edoxaban for the treatment of pulmonary embolism in hospitalized COVID-19 patients	13
Reducing potentially inappropriate polypharmacy at a national and international level: the impact of deprescribing networks	13
Efficacy of pharmacological agents for the management of treatment-resistant schizophrenia: a network meta-analysis	12
Reducing the risk of death – a possible outcome in COPD patients	12
Current understanding of the etiology of cyclic vomiting syndrome and therapeutic strategies in its management	12
Genetic markers of drug hypersensitivity in pediatrics: current state and promise	12
The future of pharmacology education: The Veterinary Educators in Pharmacology Special Interest Group (VEPSIG)	12
Dual pathway inhibition in patients with atherosclerotic disease: pharmacodynamic considerations and clinical implications	12
Emerging insights and future prospects for therapeutic application of siRNA targeting angiotensinogen in hypertension	12
Predicting drug response and toxicity in metastatic colorectal cancer: the role of germline markers	12
Why is diagnosis, investigation, and improved management of kidney stone disease important? Non-pharmacological and pharmacological treatments for nephrolithiasis	12
JAK inhibitors in dermatology: the road travelled and path ahead, a narrative review	11
Pharmacological profile of once-weekly injectable semaglutide for chronic weight management	11
Classes of drugs that target the cellular components of inflammation under clinical development for COPD	11
The effect of different contraceptive methods on the vaginal microbiome	11
Pharmacokinetics and pharmacodynamics of Hedgehog pathway inhibitors used in the treatment of advanced or treatment-refractory basal cell carcinoma	10
Effect of Wuzhi capsules on cyclosporine A concentration in children with aplastic anemia immunotherapy: a single-center observational study	10
A profile of delafloxacin in the treatment of adults with community-acquired bacterial pneumonia	10
Correction	10
Association between myocarditis and antipsychotics other than clozapine: a systematic literature review and a pharmacovigilance study using VigiBase	10
Proton pump inhibitors may reduce the risk of high-grade dysplasia and/or esophageal adenocarcinoma in Barrett’s esophagus: a systematic review and meta-analysis	10
Clozapine for treatment refractory catatonia in individuals with autism spectrum disorder: a retrospective chart review study	10
Statin-related neurocognitive disorder: a real-world pharmacovigilance study based on the FDA adverse event reporting system	10
Short-acting versus long-acting opioids for pediatric postoperative pain management	10
Blinding and expectancy confounds in psychedelic randomized controlled trials	9

Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause	9
Safety of drugs used for the treatment of migraine during pregnancy: a narrative review	9
The pharmacotherapeutics of sarcoidosis	9
Choosing the right biologic treatment for moderate-to-severe plaque psoriasis: the impact of comorbidities	9
The efficacy of vitamin D in treatment of fibromyalgia: a meta-analysis of randomized controlled studies and systematic review	9
Overcoming blinding confounds in psychedelic randomized controlled trials using biomarker driven causal mediation analysis	9
Therapeutic drug monitoring of antiretroviral therapy: current progresses and future directions	9
What is novel in the clinical management of pemphigus vulgaris?	9
Comparing the bioequivalence and safety of liraglutide in healthy Chinese subjects: an open, single-dose, randomized, repeated, two-sequence, two-cycle phase I clinical trial	9
Brimonidine tartrate ophthalmic solution 0.025% for redness relief: an overview of safety and efficacy	9
Prediction of vancomycin dose on high-dimensional data using machine learning techniques	9
What is the potential for abuse of lisdexamfetamine in adults? A preclinical and clinical literature review and expert opinion	9
Significant predictors for olanzapine pharmacokinetics: a systematic review of population pharmacokinetic studies	9
STOPP/START criteria for potentially inappropriate medications/potential prescribing omissions in older people: uptake and clinical impact	9
Novel and emerging treatment strategies for lupus nephritis	8
Do patients with immune-mediated thrombotic thrombocytopenic purpura receiving caplacizumab need antithrombotic therapy?	8
Immunotherapy for the treatment of metastatic small cell lung cancer: Focus on pembrolizumab	8
Response to letter to the editor: therapeutic importance of proteinuria classification in children with congenital anomalies of the kidney and urinary tract	8
Clinical efficacy and safety of topical difamilast in the treatment of patients with atopic dermatitis: a systematic review and meta-analysis of randomized controlled trials	8
Intravitreal immunotherapy in non-infectious uveitis: an update	8
Perspectives on deprescribing in older people with type 2 diabetes and/or cardiovascular conditions: challenges from healthcare provider, patient and caregiver perspective, and interventions to suppor	8
Clinical considerations when switching antiretroviral therapy	8
Targeting the spectrum of immune checkpoints in prostate cancer	8
Published population pharmacokinetic models of valproic acid in adult patients: a systematic review and external validation in a Chinese sample of inpatients with bipolar disorder	7
Role of tenecteplase in ischemic stroke after 4.5 hours: an evaluation of the TRACE-III trial	7
Parametric population pharmacokinetics of isoniazid: a systematic review	7
Broadening access to tenofovir alafenamide for the treatment and prevention of HIV-1 infection	7
The impact of body composition on treatment in ovarian cancer: a current insight	7
Epoprostenol for the treatment of pulmonary arterial hypertension	7
Predicting plasma concentration of quetiapine in patients with depression using machine learning techniques based on real-world evidence	7
Is ranitidine necessary as premedication for regimens containing paclitaxel? A non-inferiority study	7
Cannabidiol drug interaction considerations for prescribers and pharmacists	7
Effects of anti-diabetic treatments in type 2 diabetes and fatty liver disease	7
Colony stimulating factors for prophylaxis of chemotherapy-induced neutropenia in children	7
A comprehensive strategy to address shortage of Erwinia asparaginase in pediatric acute lymphoblastic leukemia	7
Growing role of SGLT2i in heart failure: evidence from clinical trials	7
Intraperitoneal therapy for gastric cancer peritoneal carcinomatosis	7
Therapeutic drug monitoring in kidney and liver transplantation: current advances and future directions	7
Correction	7
Therapeutic drug monitoring of carbapenem antibiotics in critically ill patients: an overview of principles, recommended dosing regimens, and clinical outcomes	7
Comparing the renal outcomes in patients with atrial fibrillation receiving different oral anticoagulants	7
Givosiran for the treatment of acute hepatic porphyria	7
Pharmacotherapy of LAMA/LABA inhaled therapy combinations for chronic obstructive pulmonary disease: a clinical overview	7
Prescription patterns of antiseizure drugs in tuberous sclerosis complex (TSC)-associated epilepsy: a multicenter cohort study from Germany and review of the literature	7
Engaging patients in conversations about deprescribing	7