OOIR: Observatory of International Research

Papers

(The median citation count of IET Systems Biology is 1. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
Excavation of gene markers associated with pancreatic ductal adenocarcinoma based on interrelationships of gene expression	40
Transcriptome sequencing and metabolome analysis to reveal renewal evidence for drought adaptation in mulberry	25
Predictor‐Based Output Feedback Control of Tumour Growth With Positive Input: Application to Antiangiogenic Therapy	17
Novel Biomarker Identification for Acute Coronary Syndrome via Integrating WGCNA and Machine Learning	13
Identifying driver modules based on multi‐omics biological networks in prostate cancer	12
A comprehensive analysis of FBN2 in bladder cancer: A risk factor and the tumour microenvironment influencer	10
Pan‐Cancer Integrative Analyses Reveal the Crosstalk Between the Intratumoral Microbiome, TP53 Mutation and Tumour Microenvironment	10
Identification and analysis of epithelial‐mesenchymal transition‐related key long non‐coding RNAs in hypospadias	9
Transcriptome Analyses Reveal the Important miRNAs Involved in Immune Response of Gastric Cancer	9
PPDTS: Predicting potential drug–target interactions based on network similarity	8
iGATTLDA: Integrative graph attention and transformer‐based model for predicting lncRNA‐Disease associations	8
Disrupted myelination network in the cingulate cortex of Parkinson's disease	7
High expression of centromere protein A and its molecular mechanism and clinical significance in prostate cancer: A study based on data mining and immunohistochemistry	7
	7
Identification of toll‐like receptor 5 and acyl‐CoA synthetase long chain family member 1 as hub genes are correlated with the severe forms of COVID‐19 by Weighted gene co‐expression network analysis	7
Human essential gene identification based on feature fusion and feature screening	6
Robust positive control of tumour growth using angiogenic inhibition	5
SRAS‐net: Low‐resolution chromosome image classification based on deep learning	5
Prediction and analysis of genetic effect in idiopathic pulmonary fibrosis and gastroesophageal reflux disease	5
Integrative Analysis of Mitochondrial‐Related Genes Reveals Diagnostic Biomarkers and Therapeutic Targets in Acute Pancreatitis	5
	5
MRANet: Multi‐Dimensional Residual Attentional Network for Precise Polyp Segmentation	5
Genes associated with diagnosis and prognosis of Burkitt lymphoma	4
Co‐Expression Transcriptomic Profiling Identifies Sex‐Universal Molecular Markers of Muscle Atrophy	4
Continuous Cuffless Blood Pressure Estimation Based on Fractional Order Derivatives via Gramian Angular Field Only Using Photoplethysmograms	4

Identification of HIBCH and MGME1 as Mitochondrial Dynamics‐Related Biomarkers in Alzheimer's Disease Via Integrated Bioinformatics Analysis	4
Identification of molecular subtypes of ischaemic stroke based on immune‐related genes and weighted co‐expression network analysis	3
Comprehensive analysis of LILR family genes expression and tumour‐infiltrating immune cells in early‐stage pancreatic ductal adenocarcinoma	3
	3
CAAFE‐ResNet: A ResNet With Channel Attention‐Augmented Feature Extraction for Prognostic Assessment in Rectal Cancer	3
SpaGraphCCI: Spatial cell–cell communication inference through GAT‐based co‐convolutional feature integration	3
PMLocMSCAM: Predicting miRNA Subcellular Localisations by miRNA Similarities and Cross‐Attention Mechanism	3
Comprehensive analysis of alternative splicing signatures in pancreatic head cancer	3
Machine learning unveils RNA polymerase II binding as a predictor for SMAD2‐dependent transcription dynamics in response to Actvin signalling	3
Cuproptosis‐related lncRNAs are correlated with tumour metabolism and immune microenvironment and predict prognosis in pancreatic cancer patients	3
Identification of an M1 Macrophages‐Related Signature for Predicting the Survival and Therapeutic Response in Gastric Cancer	3
The Potential Mechanism of Kushen Decoction in Treating Haemorrhoids: An Integration of Network Pharmacology, Molecular Docking and Molecular Dynamics Simulation	2
Gene signatures of endoplasmic reticulum stress and mitophagy for prognostic risk prediction in lung adenocarcinoma	2
Identification of the key genes and immune infiltrating cells determined by sex differences in ischaemic stroke through co‐expression network module	2
ACP‐DPE: A Dual‐Channel Deep Learning Model for Anticancer Peptide Prediction	2
	2
StackAHTPs: An explainable antihypertensive peptides identifier based on heterogeneous features and stacked learning approach	2
	2
Anoikis‐related genes as potential prognostic biomarkers in gastric cancer: A multilevel integrative analysis and predictive therapeutic value	2
DNA methylation plays important roles in lifestyle transition of Arthrobotrys oligospora	2
Cascade Aggregation Network for Accurate Polyp Segmentation	2
Adjusting laser power to control the heat generated by nanoparticles at the site of a patient's cells	2
scRSSL: Residual semi‐supervised learning with deep generative models to automatically identify cell types	1
	1
Deep‐GB: A novel deep learning model for globular protein prediction using CNN‐BiLSTM architecture and enhanced PSSM with trisection strategy	1
Gut Microbiota Mediate Periampullary Cancer Through Extracellular Matrix Proteins: A Causal Relationship Study	1
PADG‐Pred: Exploring Ensemble Approaches for Identifying Parkinson's Disease Associated Biomarkers Using Genomic Sequences Analysis	1
In silico analysis of the association between long non‐coding RNA family with sequence similarity 99 member A ( FAM99A ) and hepatic cancer	1
Hub genes and pathways in gastric cancer: A comparison between studies that used normal tissues adjacent to the tumour and studies that used healthy tissues as calibrator	1
Kinetic modelling of β ‐cell metabolism reveals control points in the insulin‐regulating pyruvate cycling pathways	1
	1
	1
Characterising and Evaluating the Immune Microenvironment Landscapes of Colorectal Cancer Shaped by Different Therapies	1
Bioinformatics approach to identify the hub gene associated with COVID‐19 and idiopathic pulmonary fibrosis	1
Investigating the Impact of Antibiotics on Environmental Microbiota Through Machine Learning Models	1
Integration of Single‐Cell RNA and Bulk RNA Sequencing Reveals Cellular Heterogeneity and Identifies Survival‐Associated Regulatory Networks in Glioblastoma	1
An immune‐related multi‐omics analysis of dolichyl‐diphosphooligosaccharide protein glycosyltransferase in glioma: Prognostic value exploration and competitive endogenous RNA network identification	1
The ‘Other’ subfamily of HECT E3 ubiquitin ligases evaluate the tumour immune microenvironment and prognosis in patients with hepatocellular carcinoma	1
Proteins Combined Score Prediction Based on Improved Gene Expression Programming Algorithm and Protein–Protein Interaction Network Characterization	1
	1
Identification of CCR7 and CBX6 as key biomarkers in abdominal aortic aneurysm: Insights from multi‐omics data and machine learning analysis	1
Inference and analysis of cell‐cell communication of non‐myeloid circulating cells in late sepsis based on single‐cell RNA‐seq	1
RYR2 mutation in non‐small cell lung cancer prolongs survival via down‐regulation of DKK1 and up‐regulation of	1
Integrated bioinformatics analysis identified leucine rich repeat containing 15 and secreted phosphoprotein 1 as hub genes for calcific aortic valve disease and osteoarthritis	1
SeqBMC: Single‐cell data processing using iterative block matrix completion algorithm based on matrix factorisation	1
	1