OOIR: Observatory of International Research

Papers

(The TQCC of IET Systems Biology is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-12-01 to 2025-12-01.)

Article	Citations
Excavation of gene markers associated with pancreatic ductal adenocarcinoma based on interrelationships of gene expression	42
Novel Biomarker Identification for Acute Coronary Syndrome via Integrating WGCNA and Machine Learning	26
Predictor‐Based Output Feedback Control of Tumour Growth With Positive Input: Application to Antiangiogenic Therapy	17
Transcriptome sequencing and metabolome analysis to reveal renewal evidence for drought adaptation in mulberry	15
A comprehensive analysis of FBN2 in bladder cancer: A risk factor and the tumour microenvironment influencer	10
iGATTLDA: Integrative graph attention and transformer‐based model for predicting lncRNA‐Disease associations	10
Identifying driver modules based on multi‐omics biological networks in prostate cancer	10
High expression of centromere protein A and its molecular mechanism and clinical significance in prostate cancer: A study based on data mining and immunohistochemistry	9
Identification and analysis of epithelial‐mesenchymal transition‐related key long non‐coding RNAs in hypospadias	8
Transcriptome Analyses Reveal the Important miRNAs Involved in Immune Response of Gastric Cancer	8
	8
Pan‐Cancer Integrative Analyses Reveal the Crosstalk Between the Intratumoral Microbiome, TP53 Mutation and Tumour Microenvironment	8
Integrative Analysis of Mitochondrial‐Related Genes Reveals Diagnostic Biomarkers and Therapeutic Targets in Acute Pancreatitis	7
Human essential gene identification based on feature fusion and feature screening	7
Disrupted myelination network in the cingulate cortex of Parkinson's disease	6
SRAS‐net: Low‐resolution chromosome image classification based on deep learning	5
Continuous Cuffless Blood Pressure Estimation Based on Fractional Order Derivatives via Gramian Angular Field Only Using Photoplethysmograms	5
Prediction and analysis of genetic effect in idiopathic pulmonary fibrosis and gastroesophageal reflux disease	5
Identification of toll‐like receptor 5 and acyl‐CoA synthetase long chain family member 1 as hub genes are correlated with the severe forms of COVID‐19 by Weighted gene co‐expression network analysis	5
	5
MRANet: Multi‐Dimensional Residual Attentional Network for Precise Polyp Segmentation	5
Robust positive control of tumour growth using angiogenic inhibition	5
Identification of HIBCH and MGME1 as Mitochondrial Dynamics‐Related Biomarkers in Alzheimer's Disease Via Integrated Bioinformatics Analysis	4
Co‐Expression Transcriptomic Profiling Identifies Sex‐Universal Molecular Markers of Muscle Atrophy	4
Cuproptosis‐related lncRNAs are correlated with tumour metabolism and immune microenvironment and predict prognosis in pancreatic cancer patients	4

Genes associated with diagnosis and prognosis of Burkitt lymphoma	4
Machine learning unveils RNA polymerase II binding as a predictor for SMAD2‐dependent transcription dynamics in response to Actvin signalling	3
A Super‐Enhancer‐Related Ferroptosis Signature Predicts Survival and Immune Microenvironment in Colon Cancer Based on Bioinformatics Analyses and Experimental Validation	3
Comprehensive analysis of alternative splicing signatures in pancreatic head cancer	3
Comprehensive analysis of LILR family genes expression and tumour‐infiltrating immune cells in early‐stage pancreatic ductal adenocarcinoma	3
PMLocMSCAM: Predicting miRNA Subcellular Localisations by miRNA Similarities and Cross‐Attention Mechanism	3
	3
SpaGraphCCI: Spatial cell–cell communication inference through GAT‐based co‐convolutional feature integration	3
Identification of molecular subtypes of ischaemic stroke based on immune‐related genes and weighted co‐expression network analysis	3
CAAFE‐ResNet: A ResNet With Channel Attention‐Augmented Feature Extraction for Prognostic Assessment in Rectal Cancer	2
Gene signatures of endoplasmic reticulum stress and mitophagy for prognostic risk prediction in lung adenocarcinoma	2
Anoikis‐related genes as potential prognostic biomarkers in gastric cancer: A multilevel integrative analysis and predictive therapeutic value	2
Hub genes and pathways in gastric cancer: A comparison between studies that used normal tissues adjacent to the tumour and studies that used healthy tissues as calibrator	2
SeqBMC: Single‐cell data processing using iterative block matrix completion algorithm based on matrix factorisation	2
	2
	2
StackAHTPs: An explainable antihypertensive peptides identifier based on heterogeneous features and stacked learning approach	2
An immune‐related multi‐omics analysis of dolichyl‐diphosphooligosaccharide protein glycosyltransferase in glioma: Prognostic value exploration and competitive endogenous RNA network identification	2
ACP‐DPE: A Dual‐Channel Deep Learning Model for Anticancer Peptide Prediction	2
Integrated bioinformatics analysis identified leucine rich repeat containing 15 and secreted phosphoprotein 1 as hub genes for calcific aortic valve disease and osteoarthritis	2
Identification of an M1 Macrophages‐Related Signature for Predicting the Survival and Therapeutic Response in Gastric Cancer	2
DNA methylation plays important roles in lifestyle transition of Arthrobotrys oligospora	2
Adjusting laser power to control the heat generated by nanoparticles at the site of a patient's cells	2
Cascade Aggregation Network for Accurate Polyp Segmentation	2
Integration of Single‐Cell RNA and Bulk RNA Sequencing Reveals Cellular Heterogeneity and Identifies Survival‐Associated Regulatory Networks in Glioblastoma	2
The Potential Mechanism of Kushen Decoction in Treating Haemorrhoids: An Integration of Network Pharmacology, Molecular Docking and Molecular Dynamics Simulation	2