OOIR: Observatory of International Research

Papers

(The TQCC of Biomarkers in Medicine is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
Immune nutrition indices are associated with disease activity in rheumatoid arthritis: a cross-sectional study	39
NLR as prognostic biomarker for metastatic renal cell carcinoma patients treated with cytoreductive nephrectomy	36
Predictive value of the Naples prognostic score for no-reflow phenomenon after saphenous vein graft stenting	34
Relationship between HE4 levels and metabolic parameters in PET of non-small cell lung cancer patients	28
Evaluation of serum salusin-α and β levels in patients with obstructive sleep apnea	26
Plasma Endostatin Correlates with Hypoxia and Mortality in Covid-19-Associated Acute Respiratory Failure	25
Prognostic Value of Serum Albumin for Long-Term Mortality in Patients with Dual-Chamber Permanent Pacemakers	22
AAT: Does it have a Place in Acute Leukemia?	22
Neutrophil-to-Serum Iron Ratio as a Promising Inflammatory Biomarker for Acute Myocardial Infarction and Gensini Score	22
Examining Variation and Temporal Dynamics of Extracellular Matrix Biomarkers Following Acute Myocardial Infarction	21
Novel Biomarkers for Acute Respiratory Distress Syndrome: Genetics, Epigenetics and Transcriptomics	21
Prognostic Value of Stc1 in Solid Tumors: A Meta-Analysis	20
Reference Interval for Urinary Neutrophil Gelatinase-Associated Lipocalin in Healthy Adults in Jiangsu Region in Eastern China: A Multicenter Study	20
Biomarkers in Exhaled Breath Condensate as Fingerprints of Asthma, Chronic Obstructive Pulmonary Disease and Asthma–Chronic Obstructive Pulmonary Disease Overlap: A Critical Review	19
A Comprehensive Review of Novel Biomarkers in the Diagnosis of Intrahepatic Cholestasis of Pregnancy	18
Torquetenovirus in bronchoalveolar lavage fluid for early detection of pulmonary infections in immunocompromised hosts	18
Meta-Analysis of Initial Natriuretic Peptides in the Setting of Sepsis-Induced Myocardial Dysfunction	17
Predictive Value of Serum Lncrna MALAT1 for the Recurrence of Persistent Atrial Fibrillation After Radiofrequency Ablation	16
Impact of Naples Prognostic Score on Midterm All-Cause Mortality in Patients with Decompensated Heart Failure	15
The association between HbA1c/C-peptide levels and short-term mortality in patients diagnosed with myocardial infarction	15
Wnt/β-Catenin Pathway Proteins in End-Stage Renal Disease	15
Evaluation of primary markers of inflammation and the systemic inflammation index in specific learning disabilities	15
Predictive Value of A Novel Lncrna LINC02518 in Evaluating the Prognosis of Patients with Hepatocellular Carcinoma	15
Elevated neutrophil-to-hemoglobin ratio as an indicator of poor survival in hepatitis B virus-related decompensated cirrhosis	15
Altered T-Cell Profile in Sickle Cell Disease	14

Designing A Fluorescence Padlock Probe-Based Biosensor and Colorimetric Assay For The Detection of G12D KRAS Mutation	14
Comprehensive biomarker profiles in hematological malignancies: improving diagnosis, prognosis, and treatment	13
TCF21 rs2327429 and TCF21 rs12190287 are Associated with Colorectal Cancer in a Chinese Population	12
IL6R Gene Polymorphisms and Their Relation to Chronic Obstructive Pulmonary Disease Susceptibility in the Chinese Population	11
Integrative Analysis of the Proteome and Transcriptome in Gastric Cancer Identified Lrp1B As A Potential Biomarker	11
Vitamin D Level Predicts Angiographic No-Reflow Phenomenon After Percutaneous Coronary Intervention in Patients with St Segment Elevation Myocardial Infarction	11
Low Serum Pepsinogen II Levels are Closely Linked with a Risk of Metabolic Syndrome among Healthy Individuals with Asymptomatic HELICOBACTER PYLORI Infection: A Cross-Se	11
Preoperative Monocyte to High-Density Lipoprotein Ratio as a Predictor of Survival Outcome of Gastric Cancer Patients After Radical Resection	11
Prognostic Value of Lymphocyte–C-Reactive Protein Ratio in Patients with Liver Cancer: A Meta-Analysis	11
Itga7 Relates to Disease Risk, Pathological Feature, Treatment Response and Survival in Ph ^– Acute Lymphoblastic Leukemia	11
The Potential of Mir-499 Plasmatic Level As A Biomarker Of Obstructive Sleep Apnea Syndrome	10
Application of 24-H Respiratory Rate and Oxygenation Index Variation to Predict the Outcome of High-Flow Nasal Cannula Therapy in Patients with Acute Hypoxemic Respiratory Failure in a Respiratory Int	10
Prognostic Impact of Cardiohepatic Syndrome in Patients with St-Segment Elevation Myocardial Infarction	10
Endothelial Biomarkers of Thrombosis in Critically Ill Patients with Acquired Coagulopathy: A Prospective Cohort Study	10
Can Anticarbamylated Protein Antibodies Be Used to Support the Diagnosis of Systemic Lupus Erythematosus?	10
Novel Marker for Predicting the Severity and Prognosis of Acute Pulmonary Embolism: Platelet-To-Hemoglobin Ratio	10
Association Between the Rs3733846 in the Flanking Region of Mir-143/145 and Risk of Cervical Squamous Cell Carcinoma	10
Lymphocyte-To-Monocyte Ratio Predicts Survival After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy	10
Association between serum corin levels and functional capacity in patients with advanced heart failure	10
Modulation of Soluble Receptor for Advanced Glycation End Products Isoforms and Advanced Glycation End Products in Long-Living Individuals	10
Nt-Probnp/Urine Hepcidin-25 Ratio and Cardiorenal Syndrome Type 1 in Patients with Severe Symptomatic Aortic Stenosis	9
Relation of A Novel Fibrosis Marker and Post-Myocardial Infarction Left Ventricular Ejection Fraction in Revascularized Patients	9
Ferroptosis-Related Genes Are Candidate Diagnostic and Prognostic Biomarkers for Skin Cutaneous Melanoma	9
Fecal Calprotectin as an Intestinal Inflammation Marker is Elevated in Glaucoma	9
Diagnostic role of circulating cell-free DNA in schizophrenia and neuro-degenerative disorders	9
Prognostic and Clinicopathological Significance of Mmp12 in Various Cancers: A Meta-Analysis and Bioinformatics Analysis	8
Serum CDC42 Reflects the Exacerbation Risk and Severity, Th1/2 Cell Imbalance and Inflammation in Asthmatic Children	8
Prognostic Value of Triglyceride/Glucose Index in Patients with St-Segment Elevation Myocardial Infarction	8
Serum Circulating Free Dna of Syncytin-1 As A Novel Molecular Marker for Early Diagnosis of Non-Small-Cell Lung Cancer	8
Exploring novel perspectives on eosinophilic inflammation in severe asthma	8
Prognostic value of C-reactive protein in patients with glioma: a meta-analysis	8
Reliable Epithelial–Mesenchymal Transition Biomarkers for Colorectal Cancer Detection	8
Nomogram for Predicting Prolonged Postoperative Ileus in Colorectal Cancer Based on Age and Inflammatory Markers	8
Gender Differences Contribute to Variability of Serum Lipid Biomarkers for Alzheimer'S Disease	8
Relationship Between Systemic Immune-Inflammation Index and No-Reflow in Percutaneous Coronary Intervention for Saphenous Grafts	7
Role of Triglyceride Glucose Index in Long-Term Mortality of Patients with Lower Extremity Arterial Disease	7
Copy Number Alteration Signatures As Biomarkers in Cancer: A Review	7
Association Of Vitamin B12/Ferritin Deficiency In Cancer Patients with Methylomic Changes At Promotors of TET Methylcytosine Dioxygenases	7
Blood MALT1 reflects acute exacerbation risk and inflammation in elderly chronic obstructive pulmonary disease patients	7
Feasibility Evaluation of Hsa_Circ_0005480 As An Auxiliary Diagnostic and Prognostic Indicator for Gastric Cancer	7
Low Vitamin K Status, High Sclerostin and Mortality Risk of Stable Coronary Heart Disease Patients	7
Comparison of the effect of Uric Acid/Albumin Ratio on Coronary Slow Flow with Other Inflammation-Based Markers	7
Urinary Iodine Concentration and Radioactive Iodine Therapeutic Response in Patients with Differentiated Thyroid Cancer	7
Evaluation of Hsp70 Levels in Ectopic Pregnancy, Abortus Imminens and Intrauterine Pregnancy	7
KELIM score predicts outcome in patients with platinum-resistant/refractory recurrent ovarian cancer	7
The relationship between serum Lumican levels and myocardial fibrosis in patients with hypertrophic cardiomyopathy	7
PLK3 is linked with higher tumor stage and unfavorable prognosis in patients with colorectal cancer	7
Investigating Adamts7 and Adamts12 Levels in Prediabetic and Type 2 Diabetic Patients	7
Predictive power of ALBI score-based nomogram for 30-day mortality following transcatheter aortic valve implantation	7
3′ Untranslated Region Variants in DEFA5 Gene Associated with Susceptibility to Iga Nephropathy in the Chinese Han Population	7

Serum vitamin D, hemoglobin A1c and vitamin B12 levels in patients with gingivitis and periodontitis stages	7
Methemoglobin in critically ill septic patients	6
Correlation Between BTG3 , Casp9 and Lrp4 Single-Nucleotide Polymorphisms and Susceptibility to Papillary T	6
Relationship Between Disease Severity and Myeloperoxidase in Chronic Viral Hepatitis: A Prospective Study	6
Interaction between coagulation and inflammatory system in liver disease: re-focus on hematological markers	6
Novel Biomarker-Based Score (Sad-60) for Predicting Mortality in Patients with Covid-19 Pneumonia: A Multicenter Retrospective Cohort of 1013 Patients	6
Immune biomarkers for predicting postoperative pneumonia following hip fracture surgery	6
Changes in Lactate Dehydrogenase on Admission Throughout the Covid-19 Pandemic and Possible Impacts on Prognostic Capability	6
High-Density Lipoprotein-Related Inflammatory Indices Predict Repeat Revascularization in Coronary Drug-Eluting Stenting	5
Prognostic Nutritional Index and Crp, Age, Platelet Count, Albumin Level Score in Predicting Mortality and Intensive Care Unit Admission for Covid-19	5
Prognostic Significance of Serum Lactate Following Cardiac Transplantation	5
Meningitis Patients with Pneumonia: Correlation Between Blood Parameters and Clinical Features	5
Analyzing venous thromboembolism risk in malignant tumors: thromboelastogram and coagulation factors study	5
Upregulation of the Transmembrane Protease Serine 3 Mrna Level in Radioresistant Colorectal Cancer Tissues	5
Mirnas As Biomarkers of Adverse Drug Reactions to Platinum-Based Agents in Patients with Non-Small-Cell Lung Cancer	5
Detection of Infections by Computerized Capture of Peaks in Longitudinally Measured C-reactive Protein Levels	5
Long-Term Stability and Age-Dependence of Six Regulatory Serum Proteins	5
Update prognostic potency of surfactant protein D (SP-D) in the COVID-19 landscape: an In-depth meta-analytical exploration	5
Evaluation of the Relationship Between Aspartate Aminotransferase/Alanine Aminotransferase Ratio and Coronary Slow-Flow Phenomenon	5
Association Between Endothelial Biomarkers and Lipid and Glycemic Levels: A Cross-Sectional Study with Diabetic Patients	5
Elevated serum vitamin B12 concentrations in a patient with pancreatic exocrine insufficiency	5
Can C-Reactive Protein be Used As a Surrogate Marker of IL-6 in a Broad Array Of Clinical Entities?	5
Association Between Serum Homocysteine and Postoperative Acute Kidney Injury in Patients Undergoing Cardiac Surgery	5
Assessing the Clinical Utility of Major Indices for Nonalcoholic Fatty Liver Disease in East Asian Populations	5
The difference in core–surface temperature indicates the prognosis of heart failure patients	5
Decreased Circulating Dipeptidyl Peptidase-4 Enzyme Activity Is Prognostic for Severe Outcomes in Covid-19 Inpatients	5
Evaluation of A Multimarker Panel in Chronic Heart Failure: A 10-Year Follow-Up	5
Risk Prediction Model of In-Hospital Mortality in Heart Failure with Preserved Ejection Fraction and Mid-Range Ejection Fraction: A Retrospective Cohort Study	5
Preoperative Red Cell Distribution Width to Lymphocyte Ratio As Biomarkers for Prolonged Intensive Care Unit Stay Among Older Patients Undergoing Cardiac Surgery: A Retrospective Longitudinal Study	5
Association between inflammatory markers and anemia in patients with diabetic foot ulcer	5
Aurora-B: a novel biomarker in the invasion and metastasis of osteosarcoma	4
A novel indicator of all-cause mortality in acute coronary syndrome: the CALLY index	4
Value of Brain Damage Biomarkers in Cerebrospinal Fluid in Neonates with Hypoxic–Ischemic Brain Injury	4
Factors Associated with Baseline and Serial Changes in Circulating Nt-Probnp and High-Sensitivity Cardiac Troponin T in A Population-Based Cohort (Dallas Heart Study)	4
Could Serum HMGB1 Levels be a Predictor Associated with Psoriatic Arthritis?	4
Relationship Between Monocyte-To-High-Density Lipoprotein Cholesterol Ratio and Excess Weight Loss in Laparoscopic Sleeve Gastrectomy	4
Predictive value of neutrophil-to-lymphocyte ratio and MELD score for short-term survival of patients with HBV-DeCi	4
Implications of Raftlin in different diseases: from molecular biology to diagnostic value	4
Predicting cerebral infarction in tuberculous meningitis and its prognostic significance	4
Ethnicity modifies the association between microRNA single nucleotide polymorphisms and pediatric acute lymphoblastic leukemia risk: a meta-analysis	4
Blood Biomarkers: A New Solution to the Silent Pandemic of Traumatic Brain Injury	4
Predicting Long-Term Cardiovascular Outcomes in Myocardial Infarction Survivors Using Multiple Biomarkers	4
Lncrna Neat1 Correlates with TH1 and TH17 and Could Serve as an Assistant Biomarker in Sepsis	4
Biomarkers: Paving the Way for Diagnosis, Prognosis and Disease Monitoring. Welcome to Volume 18	4
Serum Tissue Inhibitor of Mmp-1 Levels At Any Moment of the First Week of Spontaneous Intracerebral Hemorrhage May Predict Early Mortality	4
Biomarker Profiles in Obesity Patients and Their Relation to Cardiac Dysfunction	4
A Novel Cuproptosis-Related lncRNA Prognostic Signature in Thyroid Cancer	4
Urinary cystatin-C and urinary NGAL associated with sepsis predicts longer hospital stay in premature newborns	4
PRAMEF12 , a novel cancer/testis gene, regulates proliferation and apoptosis to promote progression of glioma	4
Nomogram Based on Neutrophil-To-Platelet Ratio to Predict In-Hospital Mortality in Infective Endocarditis	4
Urinary Tubular Biomarkers As Predictors of Death in Critically Ill Patients with Covid-19	4
Osteopontin and Galectin-3 As Biomarkers of Maladaptive Right Ventricular Remodeling In Pulmonary Hypertension	4
Novel Kidney Injury Biomarkers in A Large Cohort of Children with Sickle Cell Anemia	4
Prognostic role of systemic immune-inflammation index versus other cardiac markers in acute myocarditis in young adults	4
Hyponatremia as a predictor of complicated appendicitis: a systematic review and meta-analysis	4
Killing Three Birds with One Stone: Lncrna Malat1 As A Multifunctional Biomarker in Atherosclerotic Cardiovascular Disease	4
KELIM score predicts outcome in patients with platinum-resistant/refractory recurrent ovarian cancer	4