OOIR: Observatory of International Research

Papers

(The median citation count of Innate Immunity is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Human NK cells: From development to effector functions	65
Immune response and blood–brain barrier dysfunction during viral neuroinvasion	50
Curcumin improves necrotising microscopic colitis and cell pyroptosis by activating SIRT1/NRF2 and inhibiting the TLR4 signalling pathway in newborn rats	33
TLRs in COVID-19: How they drive immunopathology and the rationale for modulation	32
Identification of key genes and novel immune infiltration-associated biomarkers of sepsis	28
Effect of berberine on LPS-induced expression of NF-κB/MAPK signalling pathway and related inflammatory cytokines in porcine intestinal epithelial cells	25
cAMP levels regulate macrophage alternative activation marker expression	23
Circulating cell-free DNA, peripheral lymphocyte subsets alterations and neutrophil lymphocyte ratio in assessment of COVID-19 severity	22
Endotoxemia is associated with an adverse metabolic profile	21
Beneficial effect of probiotics onPseudomonas aeruginosa–infected intestinal epithelial cells through inflammatory IL-8 and antimicrobial peptide human beta-defensin-2 modulation	21
Inhibition of microRNA-128-3p alleviates liver ischaemia–reperfusion injury in mice through repressing the Rnd3/NF‐κB axis	19
Human mesenchymal stem cells inhibit the differentiation and effector functions of monocytes	15
Antimicrobial peptide LL-37 ameliorates a murine sepsis model via the induction of microvesicle release from neutrophils	14
Differential induction of innate memory in porcine monocytes by β-glucan or bacillus Calmette-Guerin	14
Chrysosplenol D protects mice against LPS-induced acute lung injury by inhibiting oxidative stress, inflammation, and apoptosis via TLR4-MAPKs/NF-κB signaling pathways	13
Pyroptosis, inflammasome, and gasdermins in tumor immunity	13
Down-regulation of hsa_circ_0045474 induces macrophage autophagy in tuberculosis via miR-582-5p/TNKS2 axis	11
Association between elevation of plasma biomarkers and monocyte dysfunction and their combination in predicting sepsis: An observational single-centre cohort study	11
Silencing Nrf2 attenuates chronic suppurative otitis media by inhibiting pro-inflammatory cytokine secretion through up-regulating TLR4	11
MiR-30a-5p ameliorates LPS-induced inflammatory injury in human A549 cells and mice via targeting RUNX2	10
Baicalin attenuates LPS-induced alveolar type II epithelial cell A549 injury by attenuation of the FSTL1 signaling pathway via increasing miR-200b-3p expression	9
Circ_0026579 alleviates LPS-induced WI-38 cells inflammation injury in infantile pneumonia	9
Anti-nociceptive effect of Portulaca oleracea L. ethanol extracts attenuated zymosan-induced mouse joint inflammation via inhibition of Nrf2 expression	9
Metabolomic analysis of spontaneous neutrophil apoptosis reveals the potential involvement of glutathione depletion	9
IL-33/ST2 axis promotes the inflammatory response of nasal mucosal epithelial cells through inducing the ERK1/2 pathway	9

Myeloid-derived suppressor cell cytokine secretion as prognostic factor in myelodysplastic syndromes	9
Long non-coding RNA ZFAS1 alleviates sepsis-induced myocardial injury via target miR-34b-5p/SIRT1	9
TheTNF-α(–238 G/A) polymorphism could protect against development of severe sepsis	9
Role of collectin-11 in innate defence against uropathogenicEscherichia coliinfection	8
Regulation of CAMP (cathelicidin antimicrobial peptide) expression in adipocytes by TLR 2 and 4	8
Wolf–Hirschhorn syndrome candidate 1 facilitates alveolar macrophage pyroptosis in sepsis-induced acute lung injury through NEK7-mediated NLRP3 inflammasome activation	7
Effects of Acanthopanax senticosus supplementation on innate immunity and changes of related immune factors in healthy mice	7
Protective effects of recombinant 53-kDa protein of Trichinella spiralis on acute lung injury in mice via alleviating lung pyroptosis by promoting M2 macrophage polarization	7
Bergamottin alleviates LPS-induced acute lung injury by inducing SIRT1 and suppressing NF-κB	7
Peptidoglycan derived from Lactobacillus rhamnosus MLGA up-regulates the expression of chicken β-defensin 9 without triggering an inflammatory response	7
Transcriptomic profiling of Brassica napus responses to Pseudomonas aeruginosa	7
miR-150 and SRPK1 regulate AKT3 expression to participate in LPS-induced inflammatory response	7
Autophagy plays a protective role duringPseudomonas aeruginosa-induced apoptosis via ROS–MAPK pathway	6
Protective effects of the notoginsenoside R1 on acute lung injury by regulating the miR-128-2-5p/Tollip signaling pathway in rats with severe acute pancreatitis	6
Silencing of circ_0000205 mitigates interleukin-1β-induced apoptosis and extracellular matrix degradation in chondrocytes via targeting miR-766-3p/ADAMTS5 axis	6
Inhibition of miR-21 ameliorates LPS-induced acute lung injury through increasing B cell lymphoma-2 expression	6
Neglected roles of IgG Fc-binding protein secreted from airway mucin-producing cells in protecting against SARS-CoV-2 infection	6
Synergistic effect of genetic polymorphisms in TLR6 and TLR10 genes on the risk of pulmonary tuberculosis in a Moldavian population	6
Oral exposure of pigs to the mycotoxin deoxynivalenol does not modulate the hepatic albumin synthesis during a LPS-induced acute-phase reaction	6
SENP3 facilitates M1 macrophage polarization via the HIF-1α/PKM2 axis in lipopolysaccharide-induced acute lung injury	6
Docosahexaenoic acid alleviates cell injury and improves barrier function by suppressing necroptosis signalling in TNF-α-challenged porcine intestinal epithelial cells	6
Susceptibility of primary human airway epithelial cells toBordetella pertussisadenylate cyclase toxin in two- and three-dimensional culture conditions	6
In uteroinflammatory challenge induces an early activation of the hepatic innate immune response in late gestation fetal sheep	5
Natural killer cell exhaustion in SARS-CoV-2 infection	5
Syphilitic infection impairs immunity by inducing both apoptosis and pyroptosis of CD4⁺ and CD8⁺ T lymphocytes	5
Role of neutrophils in different stages of atherosclerosis	5
Differential effects of the Akt pathway on the internalization ofKlebsiellaby lung epithelium and macrophages	5
Soluble CD163 is produced by monocyte-derived and alveolar macrophages, and is not associated with the severity of idiopathic pulmonary fibrosis	5
Stattic alleviates acute hepatic damage induced by LPS/d-galactosamine in mice	5
Early prolonged neutrophil activation in critically ill patients with sepsis	5
Differential susceptibility to lipopolysaccharide affects the activation of toll-like-receptor 4 signaling in THP-1 cells and PMA-differentiated THP-1 cells	5
Circulating innate lymphoid cell subtypes and altered cytokine profiles following an atherogenic high-fat diet	4
Circ_0062491 alleviates LPS-induced apoptosis and inflammation in periodontitis by regulating miR-498/SOCS6 axis	4
Indoor-related microbe damage induces complement system activation in building users	4
Lys694Arg polymorphism leads to blunted responses to LPS by interfering TLR4 with recruitment of MyD88	4
Immunoregulatory complement receptor-1 and leukocyte-associated Ig-like receptor-1 expression on leukocytes inPsoriasis vulgaris	4
Anti-HMGB1 auto-Abs influence fatigue in patients with Crohn’s disease	4
Early kinetics of calprotectin in plasma following inguinal hernia surgery	4
The effect of myeloperoxidase-oxidized LDL on THP-1 macrophage polarization and repolarization	4
From bats to pangolins: new insights into species differences in the structure and function of the immune system	4