OOIR: Observatory of International Research

Papers

(The H4-Index of Nature Protocols is 66. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Automated cGMP optical labeling of FDA-approved antibodies for human use	1300
Patient-derived ependymoma and medulloblastoma tumoroids: generation, biobanking and drug screening	1141
Author Correction: cfSNV: a software tool for the sensitive detection of somatic mutations from cell-free DNA	950
Isoform-specific RNA structure determination using Nano-DMS-MaP	684
Expansion of human pluripotent stem cell–induced nephron progenitor cells (iNPCs) and the generation of nephron organoids from iNPCs	493
Open-vessel polymerization of N-carboxyanhydride (NCA) for polypeptide synthesis	491
Open thoracic surgical implantation of cardiac pacemakers in rats	481
GLORI for absolute quantification of transcriptome-wide m6A at single-base resolution	327
ChromEMT: visualizing and reconstructing chromatin ultrastructure and 3D organization in situ	308
Fabrication of focused electron beam induced deposition tips for high-speed atomic force microscopy using benchtop scanning electron microscopy	296
Author Correction: Z-REX: shepherding reactive electrophiles to specific proteins expressed tissue specifically or ubiquitously, and recording the resultant functional electrophile-induced redox respo	252
GPSeq maps the radial organization of eukaryotic genomes along the nuclear periphery–center axis	249
Purification and functional characterization of novel human skeletal stem cell lineages	240
Spontaneous and experimental models of lymph node metastasis	239
Reproducible strategy for excisional skin-wound-healing studies in mice	235
Generating human bone marrow organoids for disease modeling and drug discovery	220
Inducible CRISPR–Cas9 screening platform to interrogate non-proliferative cellular states	216
Visualization of metabolites and microbes at high spatial resolution using MALDI mass spectrometry imaging and in situ fluorescence labeling	204
Design and application of the transformer base editor in mammalian cells and mice	171
Head-mounted central venous access during optical recordings and manipulations of neural activity in mice	170
How to isolate channel-forming membrane proteins using the E. coli expression system	150
Fabrication of thin-film electrodes and organic electrochemical transistors for neural implants	149
High-throughput fabrication of antimicrobial phage microgels and example applications in food decontamination	143
Precise tracking of nanoparticles in plant roots	139
Simplified ischemia-free liver transplantation with continuous normothermic machine perfusion	129

Rapid reaction optimization by robust and economical quantitative benchtop 19F NMR spectroscopy	129
Three-dimensional human neural culture on a chip recapitulating neuroinflammation and neurodegeneration	128
Photoimmunotechnology as a powerful biological tool for molecular-based elimination of target cells and microbes, including bacteria, fungi and viruses	123
Preparation of C4′-modified nucleoside analogs	118
Preparation and biomedical applications of single-metal atom catalysts	117
Quantitative molecular imaging using deep magnetic resonance fingerprinting	114
SubCellBarCode: integrated workflow for robust spatial proteomics by mass spectrometry	112
Small RNA structural biochemistry in a post-sequencing era	111
Spatially resolved epigenome sequencing via Tn5 transposition and deterministic DNA barcoding in tissue	111
Fabrication of electron tunneling probes for measuring single-protein conductance	110
Bioengineering human intestinal mucosal grafts using patient-derived organoids, fibroblasts and scaffolds	106
Publisher Correction: In vivo pulse labeling of isochronic cohorts of cells in the central nervous system using FlashTag	93
Sonicated inks and focused-ultrasound writing enable deep-penetration acoustic volumetric printing	92
Author Correction: Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input	92
Author Correction: Reliable detection of somatic mutations in solid tissues by laser-capture microdissection and low-input DNA sequencing	92
Publisher Correction: Rapid reaction optimization by robust and economical quantitative benchtop 19F NMR spectroscopy	91
Expansion and fluctuations-enhanced microscopy for nanoscale molecular profiling of cells and tissues	90
Large-scale growth of C. elegans and isolation of membrane protein complexes	88
Metabolomics using anion-exchange chromatography mass spectrometry for the analysis of cells, tissues and biofluids	88
Collections from Nature Protocols	86
Expansion of human hepatocytes and their application in three-dimensional culture and genetic manipulation	83
Gene expression and chromatin state mapped in space	83
Achieving transient and reversible optical transparency in live mice with tartrazine	80
A ‘print–pause–print’ protocol for 3D printing microfluidics using multimaterial stereolithography	80
A practical guide to identifying associations between tandem repeats and complex human traits using consensus genotypes from multiple tools	80
Generation of iPSC-derived human forebrain organoids assembling bilateral eye primordia	79
A versatile tissue-rolling technique for spatial-omics analyses of the entire murine gastrointestinal tract	79
Generation and long-term culture of human cerebellar organoids from pluripotent stem cells	79
mRNA lipid nanoparticle formulation, characterization and evaluation	76
Preparation of selective organ-targeting (SORT) lipid nanoparticles (LNPs) using multiple technical methods for tissue-specific mRNA delivery	75
Preparation and quantitative analysis of multicenter luminescence materials for sensing function	75
Unraveling cell–cell communication with NicheNet by inferring active ligands from transcriptomics data	74
Establishment of human induced trophoblast stem cells via reprogramming of fibroblasts	73
A new era for coral functional genomics	72
Fibrous polyisocyanide hydrogels for 3D cell culture applications	71
Drosophila melanogaster as a model host for studying Pseudomonas aeruginosa feeding infection	71
A modular method for high-throughput measurement of ion channel currents in cardiac myocytes	70
Honey bee functional genomics using symbiont-mediated RNAi	69
Sonoafterglow nanoprobes for deep-tissue imaging of peroxynitrite	69
Scalable growth of vertical graphene nanosheets by thermal chemical vapor deposition	67
Comprehensive synthesis of Ti3C2Tx from MAX phase to MXene	66
Structural connectome construction using constrained spherical deconvolution in multi-shell diffusion-weighted magnetic resonance imaging	66