OOIR: Observatory of International Research

Papers

(The H4-Index of Disease Models & Mechanisms is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Vemurafenib improves muscle histopathology in a mouse model of LAMA2-related congenital muscular dystrophy	111
A chance to turn HIV treatment up a Notch	69
RNA sequencing reveals molecular mechanisms of endometriosis lesion development in mice	61
Human organoid model of pontocerebellar hypoplasia 2a recapitulates brain region-specific size differences	58
Optimized methods to image hepatic lipid droplets in zebrafish larvae	56
Pharmacological inhibition of the acetyltransferase Tip60 mitigates myocardial infarction injury	54
Altered huntingtin−chromatin interactions predict transcriptional and epigenetic changes in Huntington's disease	48
Prostatic Escherichia coli infection drives CCR2-dependent recruitment of fibrocytes and collagen production	48
Molecular functions of ANKLE2 and its implications in human disease	47
Drop the MYC: An expansion of triple-negative breast cancer driver genes	43
Let's talk about sex… obesity and melanoma	42
Lysosomal alterations and decreased electrophysiological activity in CLN3 disease patient-derived cortical neurons	38
CIB2 function is distinct from that of whirlin in the organization of sterocilia architecture	38
Biological and therapeutic insights from animal modeling of fusion-driven pediatric soft tissue sarcomas	38
Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia	36
Interleukin-1 regulates myeloid cell trafficking and cerebral blood flow following intracerebral haemorrhage	35
The role of Lrp6-mediated Wnt/β-catenin signaling in the development and intervention of spinal neural tube defects in mice	34
Cancer cachexia: lessons from Drosophila	32
Increase in brain glycogen levels ameliorates Huntington's disease phenotype and rescues neurodegeneration in Drosophila	31
Joan Heath interviews Suzanne Cory and Joan Steitz: a female perspective of science in the swinging ‘60s	31
Pluripotent stem cell-derived neural progenitor cells can be used to model effects of IL-6 on human neurodevelopment	31
The Company of Biologists: celebrating 100 years	29
Drug-based mobilisation of mesenchymal stem/stromal cells improves cardiac function post myocardial infarction	28
frizzled 5 mutant zebrafish are genetically sensitised to developing microphthalmia and coloboma	28
Immune function and dysfunction are determined by lymphoid tissue efficacy	28

New advances in CRISPR/Cas-mediated precise gene-editing techniques	27
Validity of Xiphophorus fish as models for human disease	27
First person – Sheeza Mughal	27