OOIR: Observatory of International Research

Papers

(The H4-Index of Disease Models & Mechanisms is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)

Article	Citations
Vemurafenib improves muscle histopathology in a mouse model of LAMA2-related congenital muscular dystrophy	106
A chance to turn HIV treatment up a Notch	65
Altered huntingtin−chromatin interactions predict transcriptional and epigenetic changes in Huntington's disease	59
CIB2 function is distinct from that of whirlin in the organization of sterocilia architecture	55
Metabolism navigates neural cell fate in development, aging and neurodegeneration	55
Pharmacological inhibition of the acetyltransferase Tip60 mitigates myocardial infarction injury	52
Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia	48
Lysosomal alterations and decreased electrophysiological activity in CLN3 disease patient-derived cortical neurons	47
Human organoid model of pontocerebellar hypoplasia 2a recapitulates brain region-specific size differences	45
Molecular functions of ANKLE2 and its implications in human disease	44
Increase in brain glycogen levels ameliorates Huntington's disease phenotype and rescues neurodegeneration in Drosophila	43
Pluripotent stem cell-derived neural progenitor cells can be used to model effects of IL-6 on human neurodevelopment	39
Drop the MYC: An expansion of triple-negative breast cancer driver genes	39
Prostatic Escherichia coli infection drives CCR2-dependent recruitment of fibrocytes and collagen production	36
Let's talk about sex… obesity and melanoma	35
Biological and therapeutic insights from animal modeling of fusion-driven pediatric soft tissue sarcomas	34
RNA sequencing reveals molecular mechanisms of endometriosis lesion development in mice	33
The role of Lrp6-mediated Wnt/β-catenin signaling in the development and intervention of spinal neural tube defects in mice	33
Optimized methods to image hepatic lipid droplets in zebrafish larvae	33
Cancer cachexia: lessons from Drosophila	32
Analysis of the H-Ras mobility pattern in vivo shows cellular heterogeneity inside epidermal tissue	31
Joan Heath interviews Suzanne Cory and Joan Steitz: a female perspective of science in the swinging ‘60s	31
The Company of Biologists: celebrating 100 years	30
Abnormalities in the migration of neural precursor cells in familial bipolar disorder	29
A Drosophila model for mechanistic investigation of tau protein spread	29

frizzled 5 mutant zebrafish are genetically sensitised to developing microphthalmia and coloboma	28
A small-molecule TrkB ligand improves dendritic spine phenotypes and atypical behaviors in female Rett syndrome mice	27
First person – Sheeza Mughal	27