OOIR: Observatory of International Research

Papers

(The H4-Index of Disease Models & Mechanisms is 26. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Vemurafenib improves muscle histopathology in a mouse model of LAMA2-related congenital muscular dystrophy	106
A chance to turn HIV treatment up a Notch	68
Altered huntingtin−chromatin interactions predict transcriptional and epigenetic changes in Huntington's disease	59
Pharmacological inhibition of the acetyltransferase Tip60 mitigates myocardial infarction injury	56
CIB2 function is distinct from that of whirlin in the organization of sterocilia architecture	56
The role of Lrp6-mediated Wnt/β-catenin signaling in the development and intervention of spinal neural tube defects in mice	51
Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia	48
Molecular functions of ANKLE2 and its implications in human disease	46
Drop the MYC: An expansion of triple-negative breast cancer driver genes	44
Prostatic Escherichia coli infection drives CCR2-dependent recruitment of fibrocytes and collagen production	43
Let's talk about sex… obesity and melanoma	40
RNA sequencing reveals molecular mechanisms of endometriosis lesion development in mice	39
Cancer cachexia: lessons from Drosophila	37
Biological and therapeutic insights from animal modeling of fusion-driven pediatric soft tissue sarcomas	36
Interleukin-1 regulates myeloid cell trafficking and cerebral blood flow following intracerebral haemorrhage	34
Increase in brain glycogen levels ameliorates Huntington's disease phenotype and rescues neurodegeneration in Drosophila	33
Human organoid model of pontocerebellar hypoplasia 2a recapitulates brain region-specific size differences	32
Optimized methods to image hepatic lipid droplets in zebrafish larvae	32
Lysosomal alterations and decreased electrophysiological activity in CLN3 disease patient-derived cortical neurons	31
Immune function and dysfunction are determined by lymphoid tissue efficacy	30
Pluripotent stem cell-derived neural progenitor cells can be used to model effects of IL-6 on human neurodevelopment	30
An alveolus lung-on-a-chip model of Mycobacterium fortuitum lung infection	29
Drug-based mobilisation of mesenchymal stem/stromal cells improves cardiac function post myocardial infarction	29
Joan Heath interviews Suzanne Cory and Joan Steitz: a female perspective of science in the swinging ‘60s	28
Analysis of the H-Ras mobility pattern in vivo shows cellular heterogeneity inside epidermal tissue	28

A Drosophila model for mechanistic investigation of tau protein spread	26
The Company of Biologists: celebrating 100 years	26