OOIR: Observatory of International Research

Papers

(The H4-Index of Disease Models & Mechanisms is 27. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-11-01 to 2025-11-01.)

Article	Citations
A chance to turn HIV treatment up a Notch	113
RNA sequencing reveals molecular mechanisms of endometriosis lesion development in mice	69
Neurofibromin 1 mutations impair the function of human induced pluripotent stem cell-derived microglia	64
Interleukin-1 regulates myeloid cell trafficking and cerebral blood flow following intracerebral haemorrhage	59
Pluripotent stem cell-derived neural progenitor cells can be used to model effects of IL-6 on human neurodevelopment	59
Optimized methods to image hepatic lipid droplets in zebrafish larvae	55
Prostatic Escherichia coli infection drives CCR2-dependent recruitment of fibrocytes and collagen production	51
Altered huntingtin−chromatin interactions predict transcriptional and epigenetic changes in Huntington's disease	51
Drop the MYC: An expansion of triple-negative breast cancer driver genes	49
Let's talk about sex… obesity and melanoma	44
CIB2 function is distinct from that of whirlin in the organization of sterocilia architecture	43
Biological and therapeutic insights from animal modeling of fusion-driven pediatric soft tissue sarcomas	42
Vemurafenib improves muscle histopathology in a mouse model of LAMA2-related congenital muscular dystrophy	39
Lysosomal alterations and decreased electrophysiological activity in CLN3 disease patient-derived cortical neurons	39
Pharmacological inhibition of the acetyltransferase Tip60 mitigates myocardial infarction injury	38
Increase in brain glycogen levels ameliorates Huntington's disease phenotype and rescues neurodegeneration in Drosophila	36
The role of Lrp6-mediated Wnt/β-catenin signaling in the development and intervention of spinal neural tube defects in mice	35
Human organoid model of pontocerebellar hypoplasia 2a recapitulates brain region-specific size differences	34
Molecular functions of ANKLE2 and its implications in human disease	34
Cancer cachexia: lessons from Drosophila	32
Joan Heath interviews Suzanne Cory and Joan Steitz: a female perspective of science in the swinging ‘60s	31
The Company of Biologists: celebrating 100 years	30
Validity of Xiphophorus fish as models for human disease	29
Drug-based mobilisation of mesenchymal stem/stromal cells improves cardiac function post myocardial infarction	29
frizzled 5 mutant zebrafish are genetically sensitised to developing microphthalmia and coloboma	29

Analysis of the H-Ras mobility pattern in vivo shows cellular heterogeneity inside epidermal tissue	28
Abnormalities in the migration of neural precursor cells in familial bipolar disorder	28
Variable phenotypes and penetrance between and within different zebrafish ciliary transition zone mutants	27