Nature Chemistry

Article	Citations
Not all catenanes with oriented rings are topologically chiral	516
Bite-size science	369
Analysing allostery	364
Ethics education for chemists	330
Chemical testing	321
Stereoselective alkylation of saturated heterocycles	239
Author Correction: Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	216
Author Correction: Cytoskeleton-functionalized synthetic cells with life-like mechanical features and regulated membrane dynamicity	210
Flexible interaction patches lead to building blocks with fluctuating valency	203
Postdoc progression	197
C–H···π interactions disrupt electrostatic interactions between non-aqueous electrolytes to increase solubility	187
Diversified ring expansion of saturated cyclic amines enabled by azlactone insertion	183
Giving the green light	175
How many roads must a woman walk down?	174
Sweet as sucrose	167
Playing Lego with perylene dyes	165
Single crystals of purely organic free-standing two-dimensional woven polymer networks	158
Formylation boosts the performance of light-driven overcrowded alkene-derived rotary molecular motors	147
The anti-aromatic dianion and aromatic tetraanion of [18]annulene	146
Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo	146
Synthesis of a glycan hairpin	141
A para- to meta-isomerization of phenols	140
Photogearing as a concept for translation of precise motions at the nanoscale	139
De novo design of ribosomally synthesized and post-translationally modified peptides	137
A pseudo-cubic metal–organic cage with conformationally switchable faces for dynamically adaptive guest encapsulation	136

Protons undermine lithium-ion batteries with positively disastrous results	134
In situ nonlinear optical spectroscopy for probing buried oxide–water interfaces	133
Self-assembly of chiroptical ionic co-crystals from silver nanoclusters and organic macrocycles	131
Eric the AI research assistant for chemists	126
Aluminium analogue of oxirane	124
Cage escape governs photoredox reaction rates and quantum yields	121
Photocaged 5′ cap analogues for optical control of mRNA translation in cells	120
Chemoselective umpolung of thiols to episulfoniums for cysteine bioconjugation	117
Stereoretentive enantioconvergent reactions	116
Hydrophobic assembly of molecular catalysts at the gas–liquid–solid interface drives highly selective CO2 electromethanation	116
Phase-separation behaviour of RNAs	115
Rings of power	115
A 21-electron cobalt sandwich	113
A near-linear lanthanide complex that displays magnet-like behaviour	113
Nanomachines built from multiple components can have functional advantages	113
Enantiospecific cross-coupling of cyclic alkyl sulfones	112
Anion vacancies activate N2 to ammonia on Ba–Si orthosilicate oxynitride-hydride	111
Decentring the central science	111
Comparing notes	109
General strategy for the synthesis of N-monofluoromethyl amides	108
Author Correction: Fused radical SAM and αKG-HExxH domain proteins contain a distinct structural fold and catalyse cyclophane formation and β-hydroxylation	108
Aging-dependent evolving electrochemical potentials of biomolecular condensates regulate their physicochemical activities	108
Amphoteric chalcogen-bonding and halogen-bonding rotaxanes for anion or cation recognition	107
Oxidation of sulfur dioxide by nitrogen dioxide accelerated at the interface of deliquesced aerosol particles	105
Photoinduced stepwise charge hopping in π-stacked perylene bisimide donor–bridge–acceptor arrays	105
Thiophosphate photochemistry enables prebiotic access to sugars and terpenoid precursors	105
Accelerating stereoselective radical cross-couplings	103
Corrole and squeezed coordination	103
Accounts of academic ableism	103
The numerous paths of ferrocene	102
Total synthesis of structurally diverse pleuromutilin antibiotics	102
Supramolecular crystals for hydrogen storage	101
Protein prediction takes the prize	100
The twists and turns of chiral chemistry	99
Author Correction: Organogel delivery vehicles for the stabilization of organolithium reagents	98
Sulfone cross-coupling outcompetes proton transfer	97
A molecular sandwich with a lithium–aluminium filling	97
Publisher Correction: Collisional alignment and molecular rotation control the chemi-ionization of individual conformers of hydroquinone with metastable neon	96
Molecular basis for the diversification of lincosamide biosynthesis by pyridoxal phosphate-dependent enzymes	96
Fullerenes promote transition-metal-catalysed ammonia synthesis	96
Few-femtosecond electron transfer dynamics in photoionized donor–π–acceptor molecules	95
Chemoproteomic profiling unveils binding and functional diversity of endogenous proteins that interact with endogenous triplex DNA	93
Author Correction: The missing colours of chemistry	92
Digital skills in chemical education	92
SARS-CoV-2 simulations go exascale to predict dramatic spike opening and cryptic pockets across the proteome	92
Author Correction: The liberating force of ultrasound	91
Finding the sweet spot for chaperone activity	91
Spatiotemporal functional assembly of split protein pairs through a light-activated SpyLigation	90
Stabilizing Au2+ in a mixed-valence 3D halide perovskite	90
Dissipative DNA fibres	90

Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor	90
Activity-based directed evolution of a membrane editor in mammalian cells	89
An air- and moisture-stable ruthenium precatalyst for diverse reactivity	89
Engineering yeast to produce plant-derived anti-obesity agent	89
Atomistic simulations of the Escherichia coli ribosome provide selection criteria for translationally active substrates	89
Hydrogenative double-bond deuteration	88
Plot twist in the iron spin saga	86
Heteromultivalency enables enhanced detection of nucleic acid mutations	85
Separating fiction from fact for photocatalytic CO2 reduction	84
Interweaving different metal–organic frameworks	84
Aromatic pentaamide macrocycles bind anions with high affinity for transport across biomembranes	83
Different timescales during ultrafast stilbene isomerization in the gas and liquid phases revealed using time-resolved photoelectron spectroscopy	83
Doing away with radium’s proxies	82
Alkynes fuel free carbene formation	82
From feedstock to pharmaceuticals	82
Heterotrimeric collagen helix with high specificity of assembly results in a rapid rate of folding	82
Repurposing of halogenated organic pollutants via alkyl bromide-catalysed transfer chlorination	81
Reversing the charge of lysine by genetic code expansion	81
Precision synthesis and closed-loop recycling of ultrahigh-molar-mass cyclic polymers	80
DNA catch bonds demonstrate the art of getting stuck	79
The origin of translation	79
An interfacial role for NO2	79
Single-electron transfer between sulfonium and tryptophan enables site-selective photo crosslinking of methyllysine reader proteins	79
Catalysis-enabled amine sorting	78
Phase separation and ageing of glycine-rich protein from tick adhesive	77
Expanding the effectiveness of screening	77
Signal transduction with a swing	75
Expanding the diversity of lithium electrolytes	75
Facing the fluctuations	75
Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser	73
Keeping COFs in the loop	73
Bringing amines back into aziridination	71
Colouring by force	71
Pop-up rings to rule reactivity	71
Charting the ligandable proteome for stereoselective interactions	71
Fast track to structural biology	70
A handle on charge reorganization	70
Pathogenic bacteria remodel central metabolic enzyme to build a cyclopropanol warhead	70
Back-to-back cycloadditions in nature	69
Intersystem crossing in the entrance channel of the reaction of O(3P) with pyridine	69
Design of allosteric sites into rotary motor V1-ATPase by restoring lost function of pseudo-active sites	69
Ion-pair reorganization regulates reactivity in photoredox catalysts	68
A soil-inspired dynamically responsive chemical system for microbial modulation	68
Using symmetry to drive new protein assemblies	68
Tunable valence tautomerism in lanthanide–organic alloys	68
Biosynthesis and characterization of fuscimiditide, an aspartimidylated graspetide	68
Ultimate control in chemistry	68
Looking into the future of hybrid glasses	68
Iron–sulfur clusters as inhibitors and catalysts of viral replication	67
A 68-codon genetic code to incorporate four distinct non-canonical amino acids enabled by automated orthogonal mRNA design	67
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery	67
Visible light-driven conjunctive olefination	67
Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria	66
Near-atomic-resolution structure of J-aggregated helical light-harvesting nanotubes	66
Cobalt(II)–tetraphenylporphyrin-catalysed carbene transfer from acceptor–acceptor iodonium ylides via N-enolate–carbene radicals	66
Selective scandium ion capture through coordination templating in a covalent organic framework	66
Ultrafast proton-coupled isomerization in the phototransformation of phytochrome	66
Radiotherapy activates picolinium prodrugs in tumours	65
Enantioselective synthesis of atropisomeric indoles via iron-catalysed oxidative cross-coupling	65
Reaction-induced unsaturated Mo oxycarbides afford highly active CO2 conversion catalysts	65
Baird’s rules at the tipping point	65
Building enzymes from scratch	64
Nanopore DNA sequencing technologies and their applications towards single-molecule proteomics	64
Ribozyme for stabilized SAM analogue modifies RNA in cells	64
How synonymous mutations alter enzyme structure and function over long timescales	63
Isolation and characterization of a two-coordinate phosphinidene oxide	63
Platinum incorporation into titanate perovskites to deliver emergent active and stable platinum nanoparticles	62
Active template strategy for the preparation of π-conjugated interlocked nanocarbons	62
Controlled growth of ordered monolayers of N-heterocyclic carbenes on silicon	62
A locally activatable sensor for robust quantification of organellar glutathione	61
Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency	60
Surface stratification determines the interfacial water structure of simple electrolyte solutions	60
Copper-catalysed asymmetric hydroboration of alkenes with 1,2-benzazaborines to access chiral naphthalene isosteres	60
Isomerization of bioactive acylhydrazones triggered by light or thiols	60
A circular polyester platform based on simple gem-disubstituted valerolactones	60
Arene radiofluorination enabled by photoredox-mediated halide interconversion	59
Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions	59
Entropy-driven charge-transfer complexation yields thermally activated delayed fluorescence and highly efficient OLEDs	59
Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors	59
O-GlcNAcylation modulates liquid–liquid phase separation of SynGAP/PSD-95	59

Li–O2 battery redox mediators go positive	59
Discovery and synthesis of atropisomerically chiral acyl-substituted stable vinyl sulfoxonium ylides	58
Chemical generation of checkpoint inhibitory T cell engagers for the treatment of cancer	58
A general alkene aminoarylation enabled by N-centred radical reactivity of sulfinamides	58
Selecting aptamers with programmed affinities	58
Fullerene on non-iron cluster-matrix co-catalysts promotes collaborative H2 and N2 activation for ammonia synthesis	58
Tectonic shifts in framework chemistry	57
Aqueous interphase formed by CO2 brings electrolytes back to salt-in-water regime	57
Stereodefined alkenes with a fluoro-chloro terminus as a uniquely enabling compound class	57
A metalloenzyme platform for catalytic asymmetric radical dearomatization	57
Hydrogen splitting at a single phosphorus centre and its use for hydrogenation	56
Direct conversion of white phosphorus to versatile phosphorus transfer reagents via oxidative onioation	56
Nickel-catalysed asymmetric hydrogenation of oximes	56
Accelerating symmetry-breaking charge separation in a perylenediimide trimer through a vibronically coherent dimer intermediate	56
Enantioselective fullerene functionalization through stereochemical information transfer from a self-assembled cage	55
Enantioselective propargylic amination and related tandem sequences to α-tertiary ethynylamines and azacycles	55
Secret action of gastric acid controlling drug	54
Photoacoustic imaging of elevated glutathione in models of lung cancer for companion diagnostic applications	54
Energy-transfer-induced [3+2] cycloadditions of N–N pyridinium ylides	54
Decarboxylative cross-nucleophile coupling via ligand-to-metal charge transfer photoexcitation of Cu(ii) carboxylates	54
Tandem catalysis enables chlorine-containing waste as chlorination reagents	53
Efficient room-temperature phosphorescence of covalent organic frameworks through covalent halogen doping	53
Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner	53
φ-Aromaticity in prismatic {Bi6}-based clusters	53
Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification	53
Chemical upcycling of commodity thermoset polyurethane foams towards high-performance 3D photo-printing resins	52
Fragmentation and [4 + 3] cycloaddition in sodorifen biosynthesis	52
Recyclable and malleable thermosets enabled by activating dormant dynamic linkages	52
Isolation and reactivity of an elusive diazoalkene	52
Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins	51
Double-walled design for tetrahedral cages	51
Opportunities and challenges with hyperpolarized bioresponsive probes for functional imaging using magnetic resonance	51
Deconvoluting double layers	51
Adaptive metal ion transport and metalloregulation-driven differentiation in pluripotent synthetic cells	50
Triplet carbenes with transition-metal substituents	50
Ionic glue	49
Full-dimensional quantum stereodynamics of the non-adiabatic quenching of OH(A2Σ+) by H2	49
Combining biological and chemical diversity	49
An RNA-cleaving threose nucleic acid enzyme capable of single point mutation discrimination	49
Intramolecular alkene and functional group translocation	49
Mechanically axially chiral catenanes and noncanonical mechanically axially chiral rotaxanes	49
Publisher Correction: Visible light-driven conjunctive olefination	49
Selectivity control in hydrogenation through adaptive catalysis using ruthenium nanoparticles on a CO2-responsive support	49
Coherent photoexcitation of entangled triplet pair states	48
Publisher Correction: The blue hue of einsteinium	48
Engineering cyanine cyclizations for new fluorogenic probes	48
Fixing photocatalysts	48
Aryl ortho methoxylation	48
The eponymous ethyl alcohol	48
Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination	47
Carbonyl cross-metathesis via deoxygenative gem-di-metal catalysis	47
Hopping protons in supramolecular catalysis	47
Boron-enabled 1,3-metallate shift towards axially chiral alkenes	46
Photoinduced dual bond rotation of a nitrogen-containing system realized by chalcogen substitution	46
Publisher Correction: Photocatalytic hydrofluoroalkylation of alkenes with carboxylic acids	46
Author Correction: Entropy-driven charge-transfer complexation yields thermally activated delayed fluorescence and highly efficient OLEDs	46
High-throughput phase elucidation of polycrystalline materials using serial rotation electron diffraction	45
Thorium(iv)–antimony complexes exhibiting single, double, and triple polar covalent metal–metal bonds	45
Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase	45
Catalyst self-assembly accelerates bimetallic light-driven electrocatalytic H2 evolution in water	45
Dynamic three-dimensional structures of a metal–organic framework captured with femtosecond serial crystallography	45
A template for artificial life	44
Methylation enables high-voltage ether electrolytes for lithium metal batteries	44
A discrete antimony(v) oxide	44
Beyond Hubble	43
The blue hue of einsteinium	43
Heat flows in rock cracks naturally optimize salt compositions for ribozymes	43
D3+ formation through photoionization of the molecular D2–D2 dimer	43
How to search for Europan life	43
Photophysical oxidation of HCHO produces HO2 radicals	43
Medal for metal-free methods	42
Drawing conclusions	42
Making a start on the tenure track	42
Palladium-catalysed selective oxidative amination of olefins with Lewis basic amines	42
Photodriven nitrogen fixation by lithium hydride	42
Running rings around rings	42
Get to Know NO	42
Quinine fever	42
Chemistry just a click away	41
Assembling membraneless organelles from de novo designed proteins	41
A blueprint for catalysis	41
A general arene C–H functionalization strategy via electron donor–acceptor complex photoactivation	41
A far-red hybrid voltage indicator enabled by bioorthogonal engineering of rhodopsin on live neurons	40
Altogether changed, and yet the same	40
Practical electronics and robotics for chemists	40
Intellectual frameworks to understand complex biochemical systems at the origin of life	40
Phase by phase through a condensate researcher's career path	40
Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling	40
Bottleable triplet nitrenes	40
The search for Europan life	40
Author Correction: Cyclic polyacetylene	39
From geranium lakes to catalysis with light	39
Cellular decoding for non-natural peptides	39
Energy funnelling within multichromophore architectures monitored with subnanometre resolution	39
Molecular spins clock in	39