Nature Chemistry

Article	Citations
Not all catenanes with oriented rings are topologically chiral	451
General strategy for the synthesis of N-monofluoromethyl amides	293
Supramolecular crystals for hydrogen storage	265
DNA catch bonds demonstrate the art of getting stuck	234
Using symmetry to drive new protein assemblies	233
Pop-up rings to rule reactivity	213
A near-linear lanthanide complex that displays magnet-like behaviour	211
Protons undermine lithium-ion batteries with positively disastrous results	202
Corrole and squeezed coordination	181
Eric the AI research assistant for chemists	180
Sulfone cross-coupling outcompetes proton transfer	179
Leveraging relaxation-optimized 1H–13CF correlations in 4-19F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins	177
Function without form in synthetic polymers mimicking protein hydration	177
Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser	171
Author Correction: Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	168
A soil-inspired dynamically responsive chemical system for microbial modulation	164
Charging imide anions for batteries	162
In situ nonlinear optical spectroscopy for probing buried oxide–water interfaces	161
Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor	161
Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency	159
Enantioselective fullerene functionalization through stereochemical information transfer from a self-assembled cage	156
Discovery and synthesis of atropisomerically chiral acyl-substituted stable vinyl sulfoxonium ylides	155
Radical water opens parallel pathways in CO2 electrocatalysis	153
The numerous paths of ferrocene	151
Chiral catalysis-driven rotary molecular motors	150

Bridged bicycloalkanes through thermal [2+2] cycloaddition	150
Single crystals of purely organic free-standing two-dimensional woven polymer networks	150
Magnetic activation of spherical nucleic acids enables the remote control of synthetic cells	145
Enantiospecific cross-coupling of cyclic alkyl sulfones	145
An air- and moisture-stable ruthenium precatalyst for diverse reactivity	144
Controlling chromophore assembly and coupling via carbon nanohoops enables singlet fission at interchromophore distances up to 16 Å	141
Tunable valence tautomerism in lanthanide–organic alloys	137
Digital skills in chemical education	136
Baird’s rules at the tipping point	136
A pseudo-cubic metal–organic cage with conformationally switchable faces for dynamically adaptive guest encapsulation	134
Reaction-induced unsaturated Mo oxycarbides afford highly active CO2 conversion catalysts	134
A metalloenzyme platform for catalytic asymmetric radical dearomatization	134
Amphoteric chalcogen-bonding and halogen-bonding rotaxanes for anion or cation recognition	134
Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo	132
Modular diastereoselective synthesis of hindered cyclobutane amino nitriles through triplet nitrene-mediated ring expansion	131
Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification	131
Understanding single-molecule reactions using nanopore-based techniques	131
Metal-hydroxyls mediate intramolecular proton transfer in heterogeneous O–O bond formation	129
Fullerene on non-iron cluster-matrix co-catalysts promotes collaborative H2 and N2 activation for ammonia synthesis	127
Global profiling of arginine reactivity and ligandability in the human proteome	127
Reversible self-assembly of small molecules for recyclable solid-state battery electrolytes	125
Zigzag graphene nanoribbons with periodic porphyrin edge extensions	124
Beyond Hubble	124
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3	118
Protecting skins of Au–Cl can stabilize Au nanostructures	118
The role of aromaticity in the cyclization and polymerization of alkyne-substituted porphyrins on Au(111)	117
Heterogeneous polymer designs that bring electricity, light and substrates together	117
A dynamic metal–organic framework photocatalyst	117
Bridging aqueous electrochemistry and non-aqueous chemistry for chemical production	116
A living library concept to capture the dynamics and reactivity of mixed-metal clusters for catalysis	115
Biocompatible ligand balancing in transition metal coordination enables benign in-cell protein arylation	115
Superspreading and ultra-infiltrative coacervate mediates strong underwater adhesion on hydrated and lipidic substrates	114
Low-valent tungsten redox catalysis enables controlled isomerization and carbonylative functionalization of alkenes	114
A template for artificial life	113
A programmable biomimetic cytoskeleton	113
Excitation energy transfer and vibronic coherence in intact phycobilisomes	112
Aryl ortho methoxylation	112
Tetrafunctional cyclobutanes tune toughness via network strand continuity	109
Formal Diels–Alder reaction of saturated carboxylic acids via C–H activation	109
Photomediated aliphatic C–H functionalization	109
Homogeneous multi-payload antibody–drug conjugates	107
Mass photometric detection and quantification of nanoscale α-synuclein phase separation	106
The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein	104
Bottleable triplet nitrenes	104
Stepwise on-demand functionalization of multihydrosilanes enabled by a hydrogen-atom-transfer photocatalyst based on eosin Y	103
ATP hydrolysis captured in atomic detail	103
Single-crystal to single-crystal editing of metal–organic frameworks via ligand removal	102
A bridged backbone strategy enables collective synthesis of strychnan alkaloids	102
Aromaticity rules	98
A C–H activation-based enantioselective synthesis of lower carbo[n]helicenes	98

New-to-nature biocompatible chemistry for plastic waste upcycling	97
Optical sequencing of single synthetic polymers	97
An electroaffinity labelling platform for chemoproteomic-based target identification	97
A synthetic cell microreactor with two types of interacting dynamic DNA-based pores	95
Constructing artificial gap junctions to mediate intercellular signal and mass transport	94
D3+ formation through photoionization of the molecular D2–D2 dimer	94
Growth of single-crystal imine-linked covalent organic frameworks using amphiphilic amino-acid derivatives in water	93
A comprehensive model for the electric double layer of stepped platinum electrodes	93
Air- and photo-stable luminescent carbodicarbene-azaboraacenium ions	93
Interfacial assembly of biomimetic MOF-based porous membranes on coacervates to build complex protocells and prototissues	92
Pluralistic teaching	91
Synthesis of planar chiral ferrocenes via enantioselective remote C–H activation	91
Challenges to developing materials for the transport and storage of hydrogen	91
Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling	91
Milking riboflavin for all it’s worth	90
Covalent organic frameworks as infinite building units for metal–organic frameworks with compartmentalized pores	90
Emergence of specific binding and catalysis from a designed generalist binding protein	90
Generating extended foldamer dye stacks and unravelling their evolving exciton dynamics	90
Collisional alignment and molecular rotation control the chemi-ionization of individual conformers of hydroquinone with metastable neon	90
A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile	89
Molecular-scale dissipative chemistry drives the formation of nanoscale assemblies and their macroscale transport	89
Two roads to lithium nucleation	89
An open-shell molecule that exhibits conformational dynamics	89
Standardized excitable elements for scalable engineering of far-from-equilibrium chemical networks	89
Enabling nucleophilic reactivity in molecular calcium fluoride complexes	87
Leveraging electron donor–acceptor complexes for kinetic resolution in catalytic asymmetric photochemical synthesis	86
Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion	85
Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms	85
Photoswitchable coordination cages	84
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids	84
In vivo metallophilic self-assembly of a light-activated anticancer drug	84
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo	83
Small-molecule-catalysed deamination enables transcriptome-wide profiling of N6-methyladenosine in RNA	83
4f-orbital covalency enables a single-crystal-to-single-crystal ring-opening isomerization in a CeIV–cyclopropenyl complex	83
Artificial cell synthesis using biocatalytic polymerization-induced self-assembly	83
Molecular contacts with an orthogonal π-skeleton induce amorphization to enhance perovskite solar cell performance	82
Transient water wires mediate selective proton transport in designed channel proteins	82
Proton-triggered topological transformation in superbase-mediated selective polymerization enables access to ultrahigh-molar-mass cyclic polymers	81
Three-dimensional van der Waals open frameworks	81
Working towards a new job	80
Isolated and H2-reduced Anderson clusters catalyse low-temperature hydrogenation of CO2 to methanol	80
Engineered RNA sensors for tuberculosis detection	80
Light-activated tetrazines enable precision live-cell bioorthogonal chemistry	80
Anticancer platinum-based photo-oxidants in a new light	79
Modular chemoenzymatic synthesis of ten fusicoccane diterpenoids	79
Author Correction: Circumventing the stability problems of graphene nanoribbon zigzag edges	79
CO2 sorption in fluorinated non-porous coordination polymers	78
A physically encoded Bayesian assistant for the optimization of multicomponent reactions	78
Supramolecular assembly of molecular wires alternating crown ethers and metal–halide complexes	77
Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO2	77
Something new under the sun	76
Unravelling gas evolution mechanisms in battery electrode materials	76
An isolable germylyne radical with a one-coordinate germanium atom	75
Bistability between π-diradical open-shell and closed-shell states in indeno[1,2-a]fluorene	75
Non-statistical assembly of multicomponent [Pd2ABCD] cages	74
Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes	73
Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells	73
Unmasking the reverse catalytic activity of ‘ene’-reductases for asymmetric carbonyl desaturation	72
Strong dipole-promoted N–O bond hydrogenolysis enables ampere-level electrosynthesis of methylamine	72
Thickness control of organic semiconductor-incorporated perovskites	72
Iridium(III)-catalysed ionic hydrogenation of pyridines to multisubstituted piperidines	72
Ni-catalysed assembly of axially chiral alkenes from alkynyl tetracoordinate borons via 1,3-metallate shift	72
Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution	71
Lattice O–O ligands in Fe-incorporated hydroxides enhance water oxidation electrocatalysis	71
Construction of synthetic protein-binding non-genetic DNA systems in living cells	70
An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway	70
The impact of UV light on synthetic photochemistry and photocatalysis	69
Atomically dispersed low-valent Au boosts photocatalytic hydroxyl radical production	69
Triplet metallocarbenes featuring carbon-centred spin localization	69
Amino amide assembly	68
Photoswitchable latent monomers enable on‑demand metathesis	68
Heart of glass	68
A third strand for protein–DNA interactions	68
Future-proofing calcium fluoride	67
Looking into luciferin	67
Checking out metal cluster chemistry from living libraries	67
Cooperative ligands enable cobalt-catalysed hydrogenation	66
Sensing RNA	66
Organocatalytic enantioselective synthesis of S(IV)-stereogenic sulfinamides enabled by an air-stable chiral phosphine	66
How polymers dance to the pulses of ultrasound	66

A crystalline stannyne	65
Multi-compartment liposomes forge new paths in drug delivery	65
Masked alkynes for synthesis of threaded carbon chains	64
Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis	63
Janus-type emission from a cyclometalated iron(iii) complex	63
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	62
Spatiotemporal protein interactome profiling through condensation-enhanced photocrosslinking	62
Prebiotic synthesis of α-amino acids and orotate from α-ketoacids potentiates transition to extant metabolic pathways	62
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning	62
Upcycling chlorinated trash into synthetic organic treasure	62
Asymmetric dearomative single-atom skeletal editing of indoles and pyrroles	61
Isolation of halogen-substituted silylium ions	61
Single-crystalline two-dimensional vinylene frameworks through topological conversion	61
Quantum simulation of conical intersections using trapped ions	61
Operando film-electrochemical EPR spectroscopy tracks radical intermediates in surface-immobilized catalysts	61
Mapping the mechanisms of oxidative addition in cross-coupling reactions catalysed by phosphine-ligated Ni(0)	61
The importance of community as a pre-tenure faculty member	60
Ribose at the heart of life	60
Asymmetric construction of sulfur(VI)–fluorine cores	60
Cyclopropenium functionalization	60
Mimicking the structure and function of tau folds associated with disease	60
Establishing the fundamental rules for genetic code expansion	60
Electric field maps in enzymes	59
Structure-specific amyloid precipitation in biofluids	59
Using supramolecular machinery to engineer directional charge propagation in photoelectrochemical devices	58
A bismuth-based analogue of the π-allyl cation	58
Programmable fluorescent aptamer-based RNA switches for rapid identification of point mutations	58
ChatGPT saves the day	58
Multi-site programmable functionalization of alkenes via controllable alkene isomerization	57
On gene silencing by the X10-23 DNAzyme	57
Polymer connectivity governs electrophotocatalytic activity in the solid state	57
Adaptive insertion of a hydrophobic anchor into a poly(ethylene glycol) host for programmable surface functionalization	57
A stable, crystalline nitrogen chain radical	57
Enantioconvergent radical addition of racemic alkyl halides to access vicinal stereocentres	57
The dynamics of agonist-β2-adrenergic receptor activation induced by binding of GDP-bound Gs protein	57
Experimental quantitation of molecular conditions responsible for flow-induced polymer mechanochemistry	56
Uniform segmented platelet micelles with compositionally distinct and selectively degradable cores	56
Hyperpyramidalized alkenes with bond orders near 1.5 as synthetic building blocks	56
Spontaneous trisulfide metathesis in polar aprotic solvents	56
Non-enzymatic methylcyclization of alkenes	56
Chemical recycling of hydrofluorocarbons by transfer fluorination	56
Designer peptide–DNA cytoskeletons regulate the function of synthetic cells	55
Copper-catalysed asymmetric cross-coupling reactions tolerant of highly reactive radicals	54
Olefin π-coordination chemistry at low-oxidation-state boron	54
Zinc and manganese redox potentials in organic solvents and their influence on nickel-catalysed cross-electrophile coupling	54
Photocatalytic nitrogen fixation under an ambient atmosphere using a porous coordination polymer with bridging dinitrogen anions	54
Ten-electron count rule for the binding of adsorbates on single-atom alloy catalysts	54
A lithium–aluminium heterobimetallic dimetallocene	54
Hydration entropy of cations regulates chloride ion diffusion during electrochemical chlorine evolution	54
Encoding signal propagation on topology-programmed DNA origami	53
Exciton annihilation in molecular aggregates suppressed through quantum interference	53
The gas-phase formation mechanism of iodic acid as an atmospheric aerosol source	53
How many roads must a woman walk down?	52
Flexible interaction patches lead to building blocks with fluctuating valency	52
Rings of power	52
Stereoselective alkylation of saturated heterocycles	52
End-of-life upcycling of polyurethanes using a room temperature, mechanism-based degradation	52
A molecular sandwich with a lithium–aluminium filling	52
Reducing the carbon footprint of chemistry labs	52
Author Correction: Moiré two-dimensional covalent organic framework superlattices	51
Interweaving different metal–organic frameworks	51
Author Correction: Introducing metal–sulfur active sites in metal–organic frameworks via post-synthetic modification for hydrogenation catalysis	51
Colouring by force	50
Hydrogenative double-bond deuteration	50
Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins	50
Active template strategy for the preparation of π-conjugated interlocked nanocarbons	49
Stannole dianions for axially coordinated lanthanide single-molecule magnets	49
Different timescales during ultrafast stilbene isomerization in the gas and liquid phases revealed using time-resolved photoelectron spectroscopy	49
Degradation of G-quadruplex-binding proteins in chromatin using G4-ligand-based proteolysis-targeting chimeras	49
tRNA-deacylase-directed discovery of biosynthetic pathways	49
Doing away with radium’s proxies	48
Molecular basis for the diversification of lincosamide biosynthesis by pyridoxal phosphate-dependent enzymes	47
Heteromultivalency enables enhanced detection of nucleic acid mutations	47
Isolation and characterization of a two-coordinate phosphinidene oxide	47
Chemical upcycling of commodity thermoset polyurethane foams towards high-performance 3D photo-printing resins	46
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery	46
A para- to meta-isomerization of phenols	46
Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner	46
Photoinduced stepwise charge hopping in π-stacked perylene bisimide donor–bridge–acceptor arrays	46
Hydrogen splitting at a single phosphorus centre and its use for hydrogenation	46
Efficient room-temperature phosphorescence of covalent organic frameworks through covalent halogen doping	46
A general alkene aminoarylation enabled by N-centred radical reactivity of sulfinamides	46
Diversified ring expansion of saturated cyclic amines enabled by azlactone insertion	46
Hydrophobic assembly of molecular catalysts at the gas–liquid–solid interface drives highly selective CO2 electromethanation	45
Recyclable and malleable thermosets enabled by activating dormant dynamic linkages	45
An unnatural base pair for the detection of epigenetic cytosine modifications in DNA	45
Stepwise-controllable catalytic asymmetric Atherton–Todd reaction to access diverse P(V)-stereogenic compounds	45
Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions	45
Building ultramicroporous zirconium metal‒organic frameworks with ligands of high coordination density through a reticular approach	45
Recyclable plastics from a manganese catalyst	44
From geranium lakes to catalysis with light	44
Intramolecular alkene and functional group translocation	44
Controlling anisotropic properties by manipulating the orientation of chiral small molecules	43
Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase	43
Biosynthesis of an elusive sulfur-containing functional group	42