Nature Chemistry

Article	Citations
Not all catenanes with oriented rings are topologically chiral	372
Author Correction: Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	332
General strategy for the synthesis of N-monofluoromethyl amides	270
Supramolecular crystals for hydrogen storage	266
DNA catch bonds demonstrate the art of getting stuck	217
Using symmetry to drive new protein assemblies	213
Pop-up rings to rule reactivity	204
In situ nonlinear optical spectroscopy for probing buried oxide–water interfaces	196
Corrole and squeezed coordination	186
A near-linear lanthanide complex that displays magnet-like behaviour	183
Building enzymes from scratch	177
Reversible self-assembly of small molecules for recyclable solid-state battery electrolytes	162
Charging imide anions for batteries	160
Sulfone cross-coupling outcompetes proton transfer	157
Function without form in synthetic polymers mimicking protein hydration	157
Understanding single-molecule reactions using nanopore-based techniques	151
The numerous paths of ferrocene	149
Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser	146
Discovery and synthesis of atropisomerically chiral acyl-substituted stable vinyl sulfoxonium ylides	144
Eric the AI research assistant for chemists	143
Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo	140
Digital skills in chemical education	139
Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor	138
Magnetic activation of spherical nucleic acids enables the remote control of synthetic cells	137
Metal-hydroxyls mediate intramolecular proton transfer in heterogeneous O–O bond formation	136

Enantiospecific cross-coupling of cyclic alkyl sulfones	133
Zigzag graphene nanoribbons with periodic porphyrin edge extensions	133
Enantioselective fullerene functionalization through stereochemical information transfer from a self-assembled cage	131
Leveraging relaxation-optimized 1H–13CF correlations in 4-19F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins	131
A soil-inspired dynamically responsive chemical system for microbial modulation	130
Iron–sulfur clusters as inhibitors and catalysts of viral replication	130
An air- and moisture-stable ruthenium precatalyst for diverse reactivity	130
O-GlcNAcylation modulates liquid–liquid phase separation of SynGAP/PSD-95	129
A pseudo-cubic metal–organic cage with conformationally switchable faces for dynamically adaptive guest encapsulation	126
Protons undermine lithium-ion batteries with positively disastrous results	126
Baird’s rules at the tipping point	126
Amphoteric chalcogen-bonding and halogen-bonding rotaxanes for anion or cation recognition	126
Single crystals of purely organic free-standing two-dimensional woven polymer networks	125
Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency	124
Fullerene on non-iron cluster-matrix co-catalysts promotes collaborative H2 and N2 activation for ammonia synthesis	124
Tunable valence tautomerism in lanthanide–organic alloys	124
Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification	122
A metalloenzyme platform for catalytic asymmetric radical dearomatization	122
Bottleable triplet nitrenes	121
Beyond Hubble	121
Reaction-induced unsaturated Mo oxycarbides afford highly active CO2 conversion catalysts	121
A dynamic metal–organic framework photocatalyst	119
Heterogeneous polymer designs that bring electricity, light and substrates together	117
Bridging aqueous electrochemistry and non-aqueous chemistry for chemical production	116
Synthesis of planar chiral ferrocenes via enantioselective remote C–H activation	115
The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein	113
Photomediated aliphatic C–H functionalization	112
Insights from an information thermodynamics analysis of a synthetic molecular motor	111
Stepwise on-demand functionalization of multihydrosilanes enabled by a hydrogen-atom-transfer photocatalyst based on eosin Y	111
Aromaticity rules	111
An electroaffinity labelling platform for chemoproteomic-based target identification	110
Tetrafunctional cyclobutanes tune toughness via network strand continuity	110
Mass photometric detection and quantification of nanoscale α-synuclein phase separation	109
Air- and photo-stable luminescent carbodicarbene-azaboraacenium ions	107
Homogeneous multi-payload antibody–drug conjugates	106
D3+ formation through photoionization of the molecular D2–D2 dimer	105
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3	105
New-to-nature biocompatible chemistry for plastic waste upcycling	104
A programmable biomimetic cytoskeleton	103
Aryl ortho methoxylation	101
A template for artificial life	101
A bridged backbone strategy enables collective synthesis of strychnan alkaloids	100
Low-valent tungsten redox catalysis enables controlled isomerization and carbonylative functionalization of alkenes	100
A living library concept to capture the dynamics and reactivity of mixed-metal clusters for catalysis	99
The role of aromaticity in the cyclization and polymerization of alkyne-substituted porphyrins on Au(111)	99
Optical sequencing of single synthetic polymers	98
ATP hydrolysis captured in atomic detail	98
A C–H activation-based enantioselective synthesis of lower carbo[n]helicenes	98
Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling	96
Constructing artificial gap junctions to mediate intercellular signal and mass transport	96

Excitation energy transfer and vibronic coherence in intact phycobilisomes	96
Interfacial assembly of biomimetic MOF-based porous membranes on coacervates to build complex protocells and prototissues	95
Growth of single-crystal imine-linked covalent organic frameworks using amphiphilic amino-acid derivatives in water	95
Challenges to developing materials for the transport and storage of hydrogen	94
Multilayer stacks of polycyclic aromatic hydrocarbons	94
Pluralistic teaching	93
Leveraging electron donor–acceptor complexes for kinetic resolution in catalytic asymmetric photochemical synthesis	93
Light-activated tetrazines enable precision live-cell bioorthogonal chemistry	92
Molecular-scale dissipative chemistry drives the formation of nanoscale assemblies and their macroscale transport	92
Enabling nucleophilic reactivity in molecular calcium fluoride complexes	90
Standardized excitable elements for scalable engineering of far-from-equilibrium chemical networks	90
A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile	89
An open-shell molecule that exhibits conformational dynamics	89
Sustainable and degradable plastics	88
Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms	88
Three-dimensional van der Waals open frameworks	88
Small-molecule-catalysed deamination enables transcriptome-wide profiling of N6-methyladenosine in RNA	87
Transient water wires mediate selective proton transport in designed channel proteins	87
Covalent organic frameworks as infinite building units for metal–organic frameworks with compartmentalized pores	87
Milking riboflavin for all it’s worth	86
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids	85
4f-orbital covalency enables a single-crystal-to-single-crystal ring-opening isomerization in a CeIV–cyclopropenyl complex	85
Artificial cell synthesis using biocatalytic polymerization-induced self-assembly	85
Photoswitchable coordination cages	84
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo	84
Collisional alignment and molecular rotation control the chemi-ionization of individual conformers of hydroquinone with metastable neon	83
Molecular contacts with an orthogonal π-skeleton induce amorphization to enhance perovskite solar cell performance	83
In vivo metallophilic self-assembly of a light-activated anticancer drug	82
Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion	82
Proton-triggered topological transformation in superbase-mediated selective polymerization enables access to ultrahigh-molar-mass cyclic polymers	82
Working towards a new job	79
Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution	79
Author Correction: Circumventing the stability problems of graphene nanoribbon zigzag edges	79
CO2 sorption in fluorinated non-porous coordination polymers	79
Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO2	78
Engineered RNA sensors for tuberculosis detection	78
Something new under the sun	78
Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes	78
Iridium(III)-catalysed ionic hydrogenation of pyridines to multisubstituted piperidines	77
A physically encoded Bayesian assistant for the optimization of multicomponent reactions	77
An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway	77
Anticancer platinum-based photo-oxidants in a new light	76
Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells	75
Bistability between π-diradical open-shell and closed-shell states in indeno[1,2-a]fluorene	75
Ni-catalysed assembly of axially chiral alkenes from alkynyl tetracoordinate borons via 1,3-metallate shift	75
An isolable germylyne radical with a one-coordinate germanium atom	75
Strong dipole-promoted N–O bond hydrogenolysis enables ampere-level electrosynthesis of methylamine	74
Non-statistical assembly of multicomponent [Pd2ABCD] cages	74
The impact of UV light on synthetic photochemistry and photocatalysis	74
Tricyclic cell-penetrating peptides for efficient delivery of functional antibodies into cancer cells	74
Unmasking the reverse catalytic activity of ‘ene’-reductases for asymmetric carbonyl desaturation	74
Lattice O–O ligands in Fe-incorporated hydroxides enhance water oxidation electrocatalysis	73
Modular chemoenzymatic synthesis of ten fusicoccane diterpenoids	73
Atomically dispersed low-valent Au boosts photocatalytic hydroxyl radical production	73
Thickness control of organic semiconductor-incorporated perovskites	73
Publisher Correction: Porous covalent organic nanotubes and their assembly in loops and toroids	72
Triplet metallocarbenes featuring carbon-centred spin localization	72
A third strand for protein–DNA interactions	72
Cooperative ligands enable cobalt-catalysed hydrogenation	70
Amino amide assembly	70
Heart of glass	70
Isolation of halogen-substituted silylium ions	70
Sensing RNA	69
How polymers dance to the pulses of ultrasound	69
Multi-compartment liposomes forge new paths in drug delivery	69
Looking into luciferin	69
Upcycling chlorinated trash into synthetic organic treasure	69
Future-proofing calcium fluoride	68
Photoswitchable latent monomers enable on‑demand metathesis	68
Checking out metal cluster chemistry from living libraries	68
Prebiotic synthesis of α-amino acids and orotate from α-ketoacids potentiates transition to extant metabolic pathways	68
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	67
Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis	66
Total synthesis of nine longiborneol sesquiterpenoids using a functionalized camphor strategy	65
Quantum simulation of conical intersections using trapped ions	65
Scalable and selective deuteration of (hetero)arenes	65
Chiral control of spin-crossover dynamics in Fe(II) complexes	64
Spatiotemporal protein interactome profiling through condensation-enhanced photocrosslinking	64
Masked alkynes for synthesis of threaded carbon chains	64
A crystalline stannyne	64

Janus-type emission from a cyclometalated iron(iii) complex	64
Mapping the mechanisms of oxidative addition in cross-coupling reactions catalysed by phosphine-ligated Ni(0)	63
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning	63
Asymmetric dearomative single-atom skeletal editing of indoles and pyrroles	62
Asymmetric construction of sulfur(VI)–fluorine cores	61
The importance of community as a pre-tenure faculty member	61
Establishing the fundamental rules for genetic code expansion	61
Operando film-electrochemical EPR spectroscopy tracks radical intermediates in surface-immobilized catalysts	61
Positive climate changes	61
Mimicking the structure and function of tau folds associated with disease	60
Cyclopropenium functionalization	60
Adaptive insertion of a hydrophobic anchor into a poly(ethylene glycol) host for programmable surface functionalization	59
The dynamics of agonist-β2-adrenergic receptor activation induced by binding of GDP-bound Gs protein	59
Structure-specific amyloid precipitation in biofluids	59
Ribose at the heart of life	58
On gene silencing by the X10-23 DNAzyme	58
Electric field maps in enzymes	58
A bismuth-based analogue of the π-allyl cation	58
Olefin π-coordination chemistry at low-oxidation-state boron	57
Using supramolecular machinery to engineer directional charge propagation in photoelectrochemical devices	56
Polymer connectivity governs electrophotocatalytic activity in the solid state	56
Non-enzymatic methylcyclization of alkenes	55
Programmable fluorescent aptamer-based RNA switches for rapid identification of point mutations	55
Experimental quantitation of molecular conditions responsible for flow-induced polymer mechanochemistry	55
Hydration entropy of cations regulates chloride ion diffusion during electrochemical chlorine evolution	55
Multi-site programmable functionalization of alkenes via controllable alkene isomerization	54
ChatGPT saves the day	54
A terminal neptunium(V)–mono(oxo) complex	54
Enantioconvergent radical addition of racemic alkyl halides to access vicinal stereocentres	54
A lithium–aluminium heterobimetallic dimetallocene	54
Uniform segmented platelet micelles with compositionally distinct and selectively degradable cores	54
Photocatalytic nitrogen fixation under an ambient atmosphere using a porous coordination polymer with bridging dinitrogen anions	53
Ten-electron count rule for the binding of adsorbates on single-atom alloy catalysts	53
Zinc and manganese redox potentials in organic solvents and their influence on nickel-catalysed cross-electrophile coupling	53
Exciton annihilation in molecular aggregates suppressed through quantum interference	53
Encoding signal propagation on topology-programmed DNA origami	53
Copper-catalysed asymmetric cross-coupling reactions tolerant of highly reactive radicals	53
Designer peptide–DNA cytoskeletons regulate the function of synthetic cells	52
Rings of power	52
The gas-phase formation mechanism of iodic acid as an atmospheric aerosol source	52
Chemical testing	52
A molecular sandwich with a lithium–aluminium filling	52
End-of-life upcycling of polyurethanes using a room temperature, mechanism-based degradation	52
Doing away with radium’s proxies	52
How many roads must a woman walk down?	52
Stereoselective alkylation of saturated heterocycles	51
A para- to meta-isomerization of phenols	51
Author Correction: Moiré two-dimensional covalent organic framework superlattices	51
Author Correction: Introducing metal–sulfur active sites in metal–organic frameworks via post-synthetic modification for hydrogenation catalysis	51
Isolation and characterization of a two-coordinate phosphinidene oxide	51
Flexible interaction patches lead to building blocks with fluctuating valency	51
Reducing the carbon footprint of chemistry labs	51
Molecular basis for the diversification of lincosamide biosynthesis by pyridoxal phosphate-dependent enzymes	51
Active template strategy for the preparation of π-conjugated interlocked nanocarbons	50
Hydrogenative double-bond deuteration	50
Heteromultivalency enables enhanced detection of nucleic acid mutations	49
Colouring by force	49
Photoinduced stepwise charge hopping in π-stacked perylene bisimide donor–bridge–acceptor arrays	49
Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins	48
Diversified ring expansion of saturated cyclic amines enabled by azlactone insertion	48
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery	48
Hydrophobic assembly of molecular catalysts at the gas–liquid–solid interface drives highly selective CO2 electromethanation	48
Hydrogen splitting at a single phosphorus centre and its use for hydrogenation	48
A general alkene aminoarylation enabled by N-centred radical reactivity of sulfinamides	48
Direct conversion of white phosphorus to versatile phosphorus transfer reagents via oxidative onioation	47
Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner	47
Decarboxylative cross-nucleophile coupling via ligand-to-metal charge transfer photoexcitation of Cu(ii) carboxylates	47
Chemical upcycling of commodity thermoset polyurethane foams towards high-performance 3D photo-printing resins	47
Interweaving different metal–organic frameworks	47
Ion-pair reorganization regulates reactivity in photoredox catalysts	47
From geranium lakes to catalysis with light	46
Building ultramicroporous zirconium metal‒organic frameworks with ligands of high coordination density through a reticular approach	46
Recyclable and malleable thermosets enabled by activating dormant dynamic linkages	46
Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase	46
Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions	46
Efficient room-temperature phosphorescence of covalent organic frameworks through covalent halogen doping	46
Publisher Correction: OregonFluor enables quantitative intracellular paired agent imaging to assess drug target availability in live cells and tissues	46
Different timescales during ultrafast stilbene isomerization in the gas and liquid phases revealed using time-resolved photoelectron spectroscopy	46
Synthesis of highly strained para-cyclophanes via ring-expansion [5,5]-sigmatropic rearrangement reaction	45
Mirror-image trypsin digestion and sequencing of D-proteins	45
The fruit fly of photophysics	45
Selective arylation of atypical C–F bonds in polyfluoroarenes with aryl chlorides	45
Recyclable plastics from a manganese catalyst	45
Modular enantioselective access to β-amino amides by Brønsted acid-catalysed multicomponent reactions	45
Intramolecular alkene and functional group translocation	44
Icing a three-layer cake for predictive modelling of adsorption	44
WT19F	44
An unnatural base pair for the detection of epigenetic cytosine modifications in DNA	44
Critical race theory and its relevance for chemistry	44
Iterative synthesis of 1,3-polyboronic esters with high stereocontrol and application to the synthesis of bahamaolide A	43
Observation of robust energy transfer in the photosynthetic protein allophycocyanin using single-molecule pump–probe spectroscopy	43
Quinine fever	43
Structure-informed design of an ultrabright RNA-activated fluorophore	43
Copper catalysed asymmetric amination	43
Emulsion-oriented assembly for Janus double-spherical mesoporous nanoparticles as biological logic gates	42