Nature Chemistry

Article	Citations
Not all catenanes with oriented rings are topologically chiral	407
General strategy for the synthesis of N-monofluoromethyl amides	337
Supramolecular crystals for hydrogen storage	283
Using symmetry to drive new protein assemblies	282
Pop-up rings to rule reactivity	233
Digital skills in chemical education	222
DNA catch bonds demonstrate the art of getting stuck	219
Author Correction: Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	216
In situ nonlinear optical spectroscopy for probing buried oxide–water interfaces	212
Leveraging relaxation-optimized 1H–13CF correlations in 4-19F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins	190
Enantiospecific cross-coupling of cyclic alkyl sulfones	182
Building enzymes from scratch	180
Sulfone cross-coupling outcompetes proton transfer	174
Function without form in synthetic polymers mimicking protein hydration	173
Corrole and squeezed coordination	165
Iron–sulfur clusters as inhibitors and catalysts of viral replication	161
The numerous paths of ferrocene	159
Baird’s rules at the tipping point	153
Eric the AI research assistant for chemists	147
Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser	145
A pseudo-cubic metal–organic cage with conformationally switchable faces for dynamically adaptive guest encapsulation	139
A near-linear lanthanide complex that displays magnet-like behaviour	139
Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor	138
A soil-inspired dynamically responsive chemical system for microbial modulation	130
Protons undermine lithium-ion batteries with positively disastrous results	129

O-GlcNAcylation modulates liquid–liquid phase separation of SynGAP/PSD-95	128
Tunable valence tautomerism in lanthanide–organic alloys	128
Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification	127
Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency	125
Enantioselective fullerene functionalization through stereochemical information transfer from a self-assembled cage	124
Fullerene on non-iron cluster-matrix co-catalysts promotes collaborative H2 and N2 activation for ammonia synthesis	124
An air- and moisture-stable ruthenium precatalyst for diverse reactivity	124
Amphoteric chalcogen-bonding and halogen-bonding rotaxanes for anion or cation recognition	123
A metalloenzyme platform for catalytic asymmetric radical dearomatization	123
Discovery and synthesis of atropisomerically chiral acyl-substituted stable vinyl sulfoxonium ylides	122
Single crystals of purely organic free-standing two-dimensional woven polymer networks	120
Reaction-induced unsaturated Mo oxycarbides afford highly active CO2 conversion catalysts	120
Photomediated aliphatic C–H functionalization	119
Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo	119
D3+ formation through photoionization of the molecular D2–D2 dimer	117
Beyond Hubble	117
A living library concept to capture the dynamics and reactivity of mixed-metal clusters for catalysis	115
The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein	114
New-to-nature biocompatible chemistry for plastic waste upcycling	113
Interfacial assembly of biomimetic MOF-based porous membranes on coacervates to build complex protocells and prototissues	112
A template for artificial life	112
A programmable biomimetic cytoskeleton	112
Aryl ortho methoxylation	111
ATP hydrolysis captured in atomic detail	111
Optical sequencing of single synthetic polymers	110
Bottleable triplet nitrenes	110
A dynamic metal–organic framework photocatalyst	110
The role of aromaticity in the cyclization and polymerization of alkyne-substituted porphyrins on Au(111)	108
A bridged backbone strategy enables collective synthesis of strychnan alkaloids	107
Low-valent tungsten redox catalysis enables controlled isomerization and carbonylative functionalization of alkenes	106
Multilayer stacks of polycyclic aromatic hydrocarbons	105
Excitation energy transfer and vibronic coherence in intact phycobilisomes	105
Stepwise on-demand functionalization of multihydrosilanes enabled by a hydrogen-atom-transfer photocatalyst based on eosin Y	105
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3	104
Mass photometric detection and quantification of nanoscale α-synuclein phase separation	102
An electroaffinity labelling platform for chemoproteomic-based target identification	101
Constructing artificial gap junctions to mediate intercellular signal and mass transport	101
Challenges to developing materials for the transport and storage of hydrogen	101
Synthesis of planar chiral ferrocenes via enantioselective remote C–H activation	100
Air- and photo-stable luminescent carbodicarbene-azaboraacenium ions	100
Aromaticity rules	99
Insights from an information thermodynamics analysis of a synthetic molecular motor	99
A C–H activation-based enantioselective synthesis of lower carbo[n]helicenes	98
Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling	98
Homogeneous multi-payload antibody–drug conjugates	97
Growth of single-crystal imine-linked covalent organic frameworks using amphiphilic amino-acid derivatives in water	97
Pluralistic teaching	96
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo	95
Milking riboflavin for all it’s worth	95
Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms	93

Standardized excitable elements for scalable engineering of far-from-equilibrium chemical networks	92
4f-orbital covalency enables a single-crystal-to-single-crystal ring-opening isomerization in a CeIV–cyclopropenyl complex	92
Three-dimensional van der Waals open frameworks	92
Molecular-scale dissipative chemistry drives the formation of nanoscale assemblies and their macroscale transport	91
Enabling nucleophilic reactivity in molecular calcium fluoride complexes	90
A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile	89
Small-molecule-catalysed deamination enables transcriptome-wide profiling of N6-methyladenosine in RNA	88
Transient water wires mediate selective proton transport in designed channel proteins	88
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids	87
In vivo metallophilic self-assembly of a light-activated anticancer drug	86
An open-shell molecule that exhibits conformational dynamics	86
Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion	86
Sustainable and degradable plastics	86
Proton-triggered topological transformation in superbase-mediated selective polymerization enables access to ultrahigh-molar-mass cyclic polymers	86
Artificial cell synthesis using biocatalytic polymerization-induced self-assembly	84
Molecular contacts with an orthogonal π-skeleton induce amorphization to enhance perovskite solar cell performance	83
Collisional alignment and molecular rotation control the chemi-ionization of individual conformers of hydroquinone with metastable neon	83
Antimony cation acquired	82
Photoswitchable coordination cages	82
Mastering mono-bond metathesis	82
Working towards a new job	82
Something new under the sun	82
Light-activated tetrazines enable precision live-cell bioorthogonal chemistry	82
Author Correction: Circumventing the stability problems of graphene nanoribbon zigzag edges	81
Artificial, augmented and automated chemistry	81
An isolable germylyne radical with a one-coordinate germanium atom	80
Bistability between π-diradical open-shell and closed-shell states in indeno[1,2-a]fluorene	80
A physically encoded Bayesian assistant for the optimization of multicomponent reactions	78
Thickness control of organic semiconductor-incorporated perovskites	78
Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes	78
Strong dipole-promoted N–O bond hydrogenolysis enables ampere-level electrosynthesis of methylamine	77
Ni-catalysed assembly of axially chiral alkenes from alkynyl tetracoordinate borons via 1,3-metallate shift	77
Unmasking the reverse catalytic activity of ‘ene’-reductases for asymmetric carbonyl desaturation	77
Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells	77
Non-statistical assembly of multicomponent [Pd2ABCD] cages	76
Modular chemoenzymatic synthesis of ten fusicoccane diterpenoids	76
Atomically dispersed low-valent Au boosts photocatalytic hydroxyl radical production	75
Tricyclic cell-penetrating peptides for efficient delivery of functional antibodies into cancer cells	75
Anticancer platinum-based photo-oxidants in a new light	74
Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution	73
An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway	73
Publisher Correction: Porous covalent organic nanotubes and their assembly in loops and toroids	73
Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO2	73
A versatile approach for the synthesis of degradable polymers via controlled ring-opening metathesis copolymerization	73
Triplet metallocarbenes featuring carbon-centred spin localization	73
The impact of UV light on synthetic photochemistry and photocatalysis	73
Amino amide assembly	72
Upcycling chlorinated trash into synthetic organic treasure	72
A third strand for protein–DNA interactions	72
Quantum simulation of conical intersections using trapped ions	71
Chiral control of spin-crossover dynamics in Fe(II) complexes	71
Looking into luciferin	71
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	70
Concurrent control over sequence and dispersity in multiblock copolymers	70
Heart of glass	69
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning	69
Stoichiometric two-dimensional non-van der Waals AgCrS2 with superionic behaviour at room temperature	68
How polymers dance to the pulses of ultrasound	68
Asymmetric dearomative single-atom skeletal editing of indoles and pyrroles	67
Checking out metal cluster chemistry from living libraries	67
Multi-compartment liposomes forge new paths in drug delivery	67
Spatiotemporal protein interactome profiling through condensation-enhanced photocrosslinking	67
Isolation of halogen-substituted silylium ions	66
A crystalline stannyne	66
Janus-type emission from a cyclometalated iron(iii) complex	65
Prebiotic synthesis of α-amino acids and orotate from α-ketoacids potentiates transition to extant metabolic pathways	65
Mapping the mechanisms of oxidative addition in cross-coupling reactions catalysed by phosphine-ligated Ni(0)	64
Scalable and selective deuteration of (hetero)arenes	64
Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis	64
Total synthesis of nine longiborneol sesquiterpenoids using a functionalized camphor strategy	63
Manganese(i) complexes with metal-to-ligand charge transfer luminescence and photoreactivity	63
Operando film-electrochemical EPR spectroscopy tracks radical intermediates in surface-immobilized catalysts	63
Masked alkynes for synthesis of threaded carbon chains	63
Electric field maps in enzymes	63
A proteome-wide atlas of lysine-reactive chemistry	63
The importance of community as a pre-tenure faculty member	63
Establishing the fundamental rules for genetic code expansion	62
ChatGPT saves the day	62
Asymmetric construction of sulfur(VI)–fluorine cores	62
Positive climate changes	62

Cyclopropenium functionalization	61
Mimicking the structure and function of tau folds associated with disease	60
Experimental quantitation of molecular conditions responsible for flow-induced polymer mechanochemistry	60
Non-enzymatic methylcyclization of alkenes	60
Using supramolecular machinery to engineer directional charge propagation in photoelectrochemical devices	60
The dynamics of agonist-β2-adrenergic receptor activation induced by binding of GDP-bound Gs protein	60
Designer peptide–DNA cytoskeletons regulate the function of synthetic cells	60
A terminal neptunium(V)–mono(oxo) complex	59
Structure-specific amyloid precipitation in biofluids	59
A bismuth-based analogue of the π-allyl cation	59
The gas-phase formation mechanism of iodic acid as an atmospheric aerosol source	59
Exciton annihilation in molecular aggregates suppressed through quantum interference	59
A chiral interlocking auxiliary strategy for the synthesis of mechanically planar chiral rotaxanes	59
A lithium–aluminium heterobimetallic dimetallocene	58
Multi-site programmable functionalization of alkenes via controllable alkene isomerization	58
Photocatalytic nitrogen fixation under an ambient atmosphere using a porous coordination polymer with bridging dinitrogen anions	58
Direct dynamic read-out of molecular chirality with autonomous enzyme-driven swimmers	58
Encoding signal propagation on topology-programmed DNA origami	57
Ten-electron count rule for the binding of adsorbates on single-atom alloy catalysts	57
On gene silencing by the X10-23 DNAzyme	57
Uniform segmented platelet micelles with compositionally distinct and selectively degradable cores	57
End-of-life upcycling of polyurethanes using a room temperature, mechanism-based degradation	57
How many roads must a woman walk down?	56
A molecular sandwich with a lithium–aluminium filling	56
Ethics education for chemists	56
Adaptive insertion of a hydrophobic anchor into a poly(ethylene glycol) host for programmable surface functionalization	56
Zinc and manganese redox potentials in organic solvents and their influence on nickel-catalysed cross-electrophile coupling	56
Hydrogenative double-bond deuteration	56
Chemical testing	56
Doing away with radium’s proxies	56
Rings of power	56
Interweaving different metal–organic frameworks	55
Stereoselective alkylation of saturated heterocycles	54
Molecular basis for the diversification of lincosamide biosynthesis by pyridoxal phosphate-dependent enzymes	54
Flexible interaction patches lead to building blocks with fluctuating valency	54
Author Correction: Moiré two-dimensional covalent organic framework superlattices	54
Dissipative DNA fibres	54
Colouring by force	54
Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins	53
Isolation and characterization of a two-coordinate phosphinidene oxide	53
Photoinduced stepwise charge hopping in π-stacked perylene bisimide donor–bridge–acceptor arrays	51
Diversified ring expansion of saturated cyclic amines enabled by azlactone insertion	51
Different timescales during ultrafast stilbene isomerization in the gas and liquid phases revealed using time-resolved photoelectron spectroscopy	51
A para- to meta-isomerization of phenols	51
Hydrogen splitting at a single phosphorus centre and its use for hydrogenation	51
Hydrophobic assembly of molecular catalysts at the gas–liquid–solid interface drives highly selective CO2 electromethanation	50
Efficient room-temperature phosphorescence of covalent organic frameworks through covalent halogen doping	50
Ion-pair reorganization regulates reactivity in photoredox catalysts	50
Direct conversion of white phosphorus to versatile phosphorus transfer reagents via oxidative onioation	49
Heteromultivalency enables enhanced detection of nucleic acid mutations	49
Recyclable and malleable thermosets enabled by activating dormant dynamic linkages	49
Building ultramicroporous zirconium metal‒organic frameworks with ligands of high coordination density through a reticular approach	49
Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner	49
A general alkene aminoarylation enabled by N-centred radical reactivity of sulfinamides	48
Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions	48
Decarboxylative cross-nucleophile coupling via ligand-to-metal charge transfer photoexcitation of Cu(ii) carboxylates	48
Chemical upcycling of commodity thermoset polyurethane foams towards high-performance 3D photo-printing resins	48
Active template strategy for the preparation of π-conjugated interlocked nanocarbons	48
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery	48
Recyclable plastics from a manganese catalyst	47
Publisher Correction: OregonFluor enables quantitative intracellular paired agent imaging to assess drug target availability in live cells and tissues	47
Carbonyl cross-metathesis via deoxygenative gem-di-metal catalysis	46
Quinine fever	45
Intramolecular alkene and functional group translocation	45
Critical race theory and its relevance for chemistry	45
Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase	44
The fruit fly of photophysics	44
Tunable acetylene sorption by flexible catenated metal–organic frameworks	44
From geranium lakes to catalysis with light	44
Release of linker histone from the nucleosome driven by polyelectrolyte competition with a disordered protein	44
Controlling anisotropic properties by manipulating the orientation of chiral small molecules	44
Fused radical SAM and αKG-HExxH domain proteins contain a distinct structural fold and catalyse cyclophane formation and β-hydroxylation	44
Copper catalysed asymmetric amination	44
Arenes participate in 1,3-dipolar cycloaddition with in situ-generated diazoalkenes	44
Observation of robust energy transfer in the photosynthetic protein allophycocyanin using single-molecule pump–probe spectroscopy	43
Synthesis of highly strained para-cyclophanes via ring-expansion [5,5]-sigmatropic rearrangement reaction	43
Mirror-image trypsin digestion and sequencing of D-proteins	43
Iterative synthesis of 1,3-polyboronic esters with high stereocontrol and application to the synthesis of bahamaolide A	43
Direct visualization of ligands on gold nanoparticles in a liquid environment	43
Biosynthesis of an elusive sulfur-containing functional group	43
Navigating protein landscapes with a machine-learned transferable coarse-grained model	43
Progress and pitfalls in designing heterogeneous catalysts with molecular precision	42
Supercrystal engineering of atomically precise gold nanoparticles promoted by surface dynamics	42
Structure-informed design of an ultrabright RNA-activated fluorophore	42
Emulsion-oriented assembly for Janus double-spherical mesoporous nanoparticles as biological logic gates	42
Advances in single-molecule junctions as tools for chemical and biochemical analysis	42
Halogen-bond-assisted radical activation of glycosyl donors enables mild and stereoconvergent 1,2-cis-glycosylation	42
Low-temperature liquid platinum catalyst	42
Modular enantioselective access to β-amino amides by Brønsted acid-catalysed multicomponent reactions	41
Metastable gallium hydride mediates propane dehydrogenation on H2 co-feeding	41
Time-resolved terahertz–Raman spectroscopy reveals that cations and anions distinctly modify intermolecular interactions of water	41
Triarylmethyl cation redox mediators enhance Li–O2 battery discharge capacities	41
Enhanced active-site electric field accelerates enzyme catalysis	41
WT19F	41
Molecular-docking electrolytes enable high-voltage lithium battery chemistries	41