Nature Chemistry

Article	Citations
A near-linear lanthanide complex that displays magnet-like behaviour	539
Not all catenanes with oriented rings are topologically chiral	385
Eric the AI research assistant for chemists	383
General strategy for the synthesis of N-monofluoromethyl amides	327
Supramolecular crystals for hydrogen storage	261
Using symmetry to drive new protein assemblies	246
Mass spectrometry captures biased signalling and allosteric modulation of a G-protein-coupled receptor	217
Pop-up rings to rule reactivity	212
The origin of translation	205
Digital skills in chemical education	199
DNA catch bonds demonstrate the art of getting stuck	196
Author Correction: Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	183
Protons undermine lithium-ion batteries with positively disastrous results	178
In situ nonlinear optical spectroscopy for probing buried oxide–water interfaces	178
Corrole and squeezed coordination	163
Building enzymes from scratch	162
Iron–sulfur clusters as inhibitors and catalysts of viral replication	153
Sulfone cross-coupling outcompetes proton transfer	153
The numerous paths of ferrocene	152
Leveraging relaxation-optimized 1H–13CF correlations in 4-19F-phenylalanine as atomic beacons for probing structure and dynamics of large proteins	143
Excited-state intermediates in a designer protein encoding a phototrigger caught by an X-ray free-electron laser	139
Tunable valence tautomerism in lanthanide–organic alloys	139
A pseudo-cubic metal–organic cage with conformationally switchable faces for dynamically adaptive guest encapsulation	139
Machine learning designs new GCGR/GLP-1R dual agonists with enhanced biological potency	134
An air- and moisture-stable ruthenium precatalyst for diverse reactivity	134

Expanding the substrate scope of pyrrolysyl-transfer RNA synthetase enzymes to include non-α-amino acids in vitro and in vivo	133
A metalloenzyme platform for catalytic asymmetric radical dearomatization	130
The twists and turns of chiral chemistry	124
Discovery and synthesis of atropisomerically chiral acyl-substituted stable vinyl sulfoxonium ylides	123
A soil-inspired dynamically responsive chemical system for microbial modulation	123
Reaction-induced unsaturated Mo oxycarbides afford highly active CO2 conversion catalysts	123
Enantiospecific cross-coupling of cyclic alkyl sulfones	122
Baird’s rules at the tipping point	121
Digital micelles of encoded polymeric amphiphiles for direct sequence reading and ex vivo label-free quantification	119
Enantioselective fullerene functionalization through stereochemical information transfer from a self-assembled cage	116
Fullerene on non-iron cluster-matrix co-catalysts promotes collaborative H2 and N2 activation for ammonia synthesis	116
Amphoteric chalcogen-bonding and halogen-bonding rotaxanes for anion or cation recognition	116
Single crystals of purely organic free-standing two-dimensional woven polymer networks	114
O-GlcNAcylation modulates liquid–liquid phase separation of SynGAP/PSD-95	114
Photomediated aliphatic C–H functionalization	113
D3+ formation through photoionization of the molecular D2–D2 dimer	113
A programmable biomimetic cytoskeleton	113
Beyond Hubble	113
Excitation energy transfer and vibronic coherence in intact phycobilisomes	112
Low-valent tungsten redox catalysis enables controlled isomerization and carbonylative functionalization of alkenes	111
A template for artificial life	110
Aryl ortho methoxylation	108
ATP hydrolysis captured in atomic detail	108
The role of aromaticity in the cyclization and polymerization of alkyne-substituted porphyrins on Au(111)	107
Insights from an information thermodynamics analysis of a synthetic molecular motor	105
Combining biological and chemical diversity	105
A dynamic metal–organic framework photocatalyst	105
Bottleable triplet nitrenes	105
Synthesis and single-molecule imaging reveal stereospecific enhancement of binding kinetics by the antitumour eEF1A antagonist SR-A3	104
The ribosome stabilizes partially folded intermediates of a nascent multi-domain protein	103
Global profiling of functional histidines in live cells using small-molecule photosensitizer and chemical probe relay labelling	103
Constructing artificial gap junctions to mediate intercellular signal and mass transport	103
A bridged backbone strategy enables collective synthesis of strychnan alkaloids	102
Mass photometric detection and quantification of nanoscale α-synuclein phase separation	101
A catalytic asymmetric cross-coupling approach to the synthesis of cyclobutanes	101
Multilayer stacks of polycyclic aromatic hydrocarbons	100
Growth of single-crystal imine-linked covalent organic frameworks using amphiphilic amino-acid derivatives in water	98
Synthesis of planar chiral ferrocenes via enantioselective remote C–H activation	98
An electroaffinity labelling platform for chemoproteomic-based target identification	97
A C–H activation-based enantioselective synthesis of lower carbo[n]helicenes	97
Air- and photo-stable luminescent carbodicarbene-azaboraacenium ions	95
Stepwise on-demand functionalization of multihydrosilanes enabled by a hydrogen-atom-transfer photocatalyst based on eosin Y	94
Homogeneous multi-payload antibody–drug conjugates	94
Aromaticity rules	94
A living library concept to capture the dynamics and reactivity of mixed-metal clusters for catalysis	93
Optical sequencing of single synthetic polymers	93
Challenges to developing materials for the transport and storage of hydrogen	93
Pluralistic teaching	92
Milking riboflavin for all it’s worth	91
An open-shell molecule that exhibits conformational dynamics	89

4f-orbital covalency enables a single-crystal-to-single-crystal ring-opening isomerization in a CeIV–cyclopropenyl complex	89
Molecular contacts with an orthogonal π-skeleton induce amorphization to enhance perovskite solar cell performance	89
Transient water wires mediate selective proton transport in designed channel proteins	87
A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile	86
Protein semisynthesis reveals plasticity in HECT E3 ubiquitin ligase mechanisms	85
Designing artificial fluorescent proteins and biosensors by genetically encoding molecular rotor-based amino acids	85
Molecular-scale dissipative chemistry drives the formation of nanoscale assemblies and their macroscale transport	85
Enabling nucleophilic reactivity in molecular calcium fluoride complexes	85
Small-molecule-catalysed deamination enables transcriptome-wide profiling of N6-methyladenosine in RNA	84
Deciphering functional roles of protein succinylation and glutarylation using genetic code expansion	84
Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo	84
In vivo metallophilic self-assembly of a light-activated anticancer drug	83
Three-dimensional van der Waals open frameworks	83
Light-activated tetrazines enable precision live-cell bioorthogonal chemistry	81
Proton-triggered topological transformation in superbase-mediated selective polymerization enables access to ultrahigh-molar-mass cyclic polymers	81
Standardized excitable elements for scalable engineering of far-from-equilibrium chemical networks	80
Sustainable and degradable plastics	80
Artificial cell synthesis using biocatalytic polymerization-induced self-assembly	80
Photoswitchable coordination cages	80
Collisional alignment and molecular rotation control the chemi-ionization of individual conformers of hydroquinone with metastable neon	80
Colloidal metallurgy	79
Antimony cation acquired	78
Working towards a new job	78
Something new under the sun	78
A physically encoded Bayesian assistant for the optimization of multicomponent reactions	77
The gains from breaking symmetry	77
Artificial, augmented and automated chemistry	76
Author Correction: Circumventing the stability problems of graphene nanoribbon zigzag edges	76
An evolved artificial radical cyclase enables the construction of bicyclic terpenoid scaffolds via an H-atom transfer pathway	76
Mastering mono-bond metathesis	76
Modular chemoenzymatic synthesis of ten fusicoccane diterpenoids	75
Anticancer platinum-based photo-oxidants in a new light	75
Bistability between π-diradical open-shell and closed-shell states in indeno[1,2-a]fluorene	74
An isolable germylyne radical with a one-coordinate germanium atom	74
Unmasking the reverse catalytic activity of ‘ene’-reductases for asymmetric carbonyl desaturation	73
A versatile approach for the synthesis of degradable polymers via controlled ring-opening metathesis copolymerization	73
Protein nanopore reveals the renin–angiotensin system crosstalk with single-amino-acid resolution	72
Aldehyde-catalysed carboxylate exchange in α-amino acids with isotopically labelled CO2	71
Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells	71
Direct mapping of ligandable tyrosines and lysines in cells with chiral sulfonyl fluoride probes	70
The impact of UV light on synthetic photochemistry and photocatalysis	70
Thickness control of organic semiconductor-incorporated perovskites	70
Non-statistical assembly of multicomponent [Pd2ABCD] cages	70
Integrating programmable DNAzymes with electrical readout for rapid and culture-free bacterial detection using a handheld platform	70
Ni-catalysed assembly of axially chiral alkenes from alkynyl tetracoordinate borons via 1,3-metallate shift	70
Tricyclic cell-penetrating peptides for efficient delivery of functional antibodies into cancer cells	69
Atomically dispersed low-valent Au boosts photocatalytic hydroxyl radical production	69
A third strand for protein–DNA interactions	68
Publisher Correction: Porous covalent organic nanotubes and their assembly in loops and toroids	68
Triplet metallocarbenes featuring carbon-centred spin localization	68
How polymers dance to the pulses of ultrasound	68
Upcycling chlorinated trash into synthetic organic treasure	67
Checking out metal cluster chemistry from living libraries	66
Heart of glass	66
Amino amide assembly	66
Spatiotemporal protein interactome profiling through condensation-enhanced photocrosslinking	65
Looking into luciferin	65
Discovery of the selenium-containing antioxidant ovoselenol derived from convergent evolution	65
Quantum simulation of conical intersections using trapped ions	65
Stoichiometric two-dimensional non-van der Waals AgCrS2 with superionic behaviour at room temperature	65
Prebiotic synthesis of α-amino acids and orotate from α-ketoacids potentiates transition to extant metabolic pathways	64
Enabling late-stage drug diversification by high-throughput experimentation with geometric deep learning	64
Concurrent control over sequence and dispersity in multiblock copolymers	63
Operando film-electrochemical EPR spectroscopy tracks radical intermediates in surface-immobilized catalysts	63
Manganese(i) complexes with metal-to-ligand charge transfer luminescence and photoreactivity	63
Chiral control of spin-crossover dynamics in Fe(II) complexes	62
Scalable and selective deuteration of (hetero)arenes	62
A crystalline stannyne	61
Janus-type emission from a cyclometalated iron(iii) complex	61
Masked alkynes for synthesis of threaded carbon chains	61
Asymmetric dearomative single-atom skeletal editing of indoles and pyrroles	60
A ring expansion strategy towards diverse azaheterocycles	59
A proteome-wide atlas of lysine-reactive chemistry	59
Tandem intermolecular [4 + 2] cycloadditions are catalysed by glycosylated enzymes for natural product biosynthesis	59
Multi-compartment liposomes forge new paths in drug delivery	59
Total synthesis of nine longiborneol sesquiterpenoids using a functionalized camphor strategy	59
Mapping the mechanisms of oxidative addition in cross-coupling reactions catalysed by phosphine-ligated Ni(0)	59
Positive climate changes	58
Asymmetric construction of sulfur(VI)–fluorine cores	58
Electric field maps in enzymes	58

Cyclopropenium functionalization	58
ChatGPT saves the day	58
The importance of community as a pre-tenure faculty member	58
Establishing the fundamental rules for genetic code expansion	58
Non-enzymatic methylcyclization of alkenes	58
Encoding signal propagation on topology-programmed DNA origami	57
Structure-specific amyloid precipitation in biofluids	57
A terminal neptunium(V)–mono(oxo) complex	57
On gene silencing by the X10-23 DNAzyme	56
Direct dynamic read-out of molecular chirality with autonomous enzyme-driven swimmers	56
Adaptive insertion of a hydrophobic anchor into a poly(ethylene glycol) host for programmable surface functionalization	55
Multi-site programmable functionalization of alkenes via controllable alkene isomerization	55
Experimental quantitation of molecular conditions responsible for flow-induced polymer mechanochemistry	55
Exciton annihilation in molecular aggregates suppressed through quantum interference	55
Mimicking the structure and function of tau folds associated with disease	55
The dynamics of agonist-β2-adrenergic receptor activation induced by binding of GDP-bound Gs protein	54
Zinc and manganese redox potentials in organic solvents and their influence on nickel-catalysed cross-electrophile coupling	54
Ten-electron count rule for the binding of adsorbates on single-atom alloy catalysts	54
Using supramolecular machinery to engineer directional charge propagation in photoelectrochemical devices	54
Switching on prodrugs using radiotherapy	54
Designer peptide–DNA cytoskeletons regulate the function of synthetic cells	54
A lithium–aluminium heterobimetallic dimetallocene	53
Uniform segmented platelet micelles with compositionally distinct and selectively degradable cores	53
A chiral interlocking auxiliary strategy for the synthesis of mechanically planar chiral rotaxanes	53
End-of-life upcycling of polyurethanes using a room temperature, mechanism-based degradation	53
Photocatalytic nitrogen fixation under an ambient atmosphere using a porous coordination polymer with bridging dinitrogen anions	53
The gas-phase formation mechanism of iodic acid as an atmospheric aerosol source	53
Rings of power	52
Chemical testing	52
Ethics education for chemists	52
How many roads must a woman walk down?	52
Bite-size science	52
Hydrogenative double-bond deuteration	51
Accounts of academic ableism	51
Doing away with radium’s proxies	50
A molecular sandwich with a lithium–aluminium filling	50
Interweaving different metal–organic frameworks	49
Flexible interaction patches lead to building blocks with fluctuating valency	49
Isolation and characterization of a two-coordinate phosphinidene oxide	49
Expanding the effectiveness of screening	49
Stereoselective alkylation of saturated heterocycles	49
Molecular basis for the diversification of lincosamide biosynthesis by pyridoxal phosphate-dependent enzymes	49
Colouring by force	49
A para- to meta-isomerization of phenols	49
Heteromultivalency enables enhanced detection of nucleic acid mutations	48
Different timescales during ultrafast stilbene isomerization in the gas and liquid phases revealed using time-resolved photoelectron spectroscopy	48
Dissipative DNA fibres	48
Photoinduced stepwise charge hopping in π-stacked perylene bisimide donor–bridge–acceptor arrays	48
Decarboxylative cross-nucleophile coupling via ligand-to-metal charge transfer photoexcitation of Cu(ii) carboxylates	47
Author Correction: Moiré two-dimensional covalent organic framework superlattices	47
Nanoparticle stereochemistry-dependent endocytic processing improves in vivo mRNA delivery	47
Chemical upcycling of commodity thermoset polyurethane foams towards high-performance 3D photo-printing resins	47
Active template strategy for the preparation of π-conjugated interlocked nanocarbons	47
Diversified ring expansion of saturated cyclic amines enabled by azlactone insertion	47
A general alkene aminoarylation enabled by N-centred radical reactivity of sulfinamides	47
Efficient room-temperature phosphorescence of covalent organic frameworks through covalent halogen doping	46
Direct conversion of white phosphorus to versatile phosphorus transfer reagents via oxidative onioation	46
Tectonic shifts in framework chemistry	46
Selection of a promiscuous minimalist cAMP phosphodiesterase from a library of de novo designed proteins	46
Ion-pair reorganization regulates reactivity in photoredox catalysts	46
Reconfiguring hydrogel assemblies using a photocontrolled metallopolymer adhesive for multiple customized functions	46
Near-infrared-activated anticancer platinum(IV) complexes directly photooxidize biomolecules in an oxygen-independent manner	45
Publisher Correction: OregonFluor enables quantitative intracellular paired agent imaging to assess drug target availability in live cells and tissues	45
Hydrophobic assembly of molecular catalysts at the gas–liquid–solid interface drives highly selective CO2 electromethanation	45
Recyclable and malleable thermosets enabled by activating dormant dynamic linkages	45
Hydrogen splitting at a single phosphorus centre and its use for hydrogenation	45
Iterative synthesis of 1,3-polyboronic esters with high stereocontrol and application to the synthesis of bahamaolide A	44
Release of linker histone from the nucleosome driven by polyelectrolyte competition with a disordered protein	44
Arenes participate in 1,3-dipolar cycloaddition with in situ-generated diazoalkenes	44
Advances in single-molecule junctions as tools for chemical and biochemical analysis	44
Recyclable plastics from a manganese catalyst	44
Copper catalysed asymmetric amination	43
Quinine fever	43
Structural basis of the Meinwald rearrangement catalysed by styrene oxide isomerase	43
Carbonyl cross-metathesis via deoxygenative gem-di-metal catalysis	43
Observation of robust energy transfer in the photosynthetic protein allophycocyanin using single-molecule pump–probe spectroscopy	43
Halogen-bond-assisted radical activation of glycosyl donors enables mild and stereoconvergent 1,2-cis-glycosylation	43
Critical race theory and its relevance for chemistry	43
Progress and pitfalls in designing heterogeneous catalysts with molecular precision	43
Triarylmethyl cation redox mediators enhance Li–O2 battery discharge capacities	42
WT19F	42
Direct visualization of ligands on gold nanoparticles in a liquid environment	42
From geranium lakes to catalysis with light	42
Low-temperature liquid platinum catalyst	42
Metastable gallium hydride mediates propane dehydrogenation on H2 co-feeding	42
The fruit fly of photophysics	41
Enhanced active-site electric field accelerates enzyme catalysis	41
Supercrystal engineering of atomically precise gold nanoparticles promoted by surface dynamics	41
Tunable and recyclable polyesters from CO2 and butadiene	41
Mirror-image trypsin digestion and sequencing of D-proteins	41
Time-resolved terahertz–Raman spectroscopy reveals that cations and anions distinctly modify intermolecular interactions of water	41
Intramolecular alkene and functional group translocation	41
Fused radical SAM and αKG-HExxH domain proteins contain a distinct structural fold and catalyse cyclophane formation and β-hydroxylation	40
Controlling anisotropic properties by manipulating the orientation of chiral small molecules	40
Structure-informed design of an ultrabright RNA-activated fluorophore	40