OOIR: Observatory of International Research

Papers

(The median citation count of Biodata Mining is 2. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-10-01 to 2025-10-01.)

Article	Citations
Investigating potential drug targets for IgA nephropathy and membranous nephropathy through multi-queue plasma protein analysis: a Mendelian randomization study based on SMR and co-localization analys	368
Correction: Detection and classification of long terminal repeat sequences in plant LTR-retrotransposons and their analysis using explainable machine learning	320
Processing imbalanced medical data at the data level with assisted-reproduction data as an example	64
Exploring the common genetic basis of metabolic syndrome-related diseases and chronic kidney disease: insights from extensive genome-wide cross-trait analyses	64
MOCAT: multi-omics integration with auxiliary classifiers enhanced autoencoder	53
Deep joint learning diagnosis of Alzheimer’s disease based on multimodal feature fusion	52
A simple guide to the use of Student’s t-test, Mann-Whitney U test, Chi-squared test, and Kruskal-Wallis test in biostatistics	35
Transcriptome-based network analysis related to regulatory T cells infiltration identified RCN1 as a potential biomarker for prognosis in clear cell renal cell carcinoma	29
Polygenic risk modeling of tumor stage and survival in bladder cancer	27
Unsupervised clustering based coronary artery segmentation	25
circGPAcorr: an integrative tool for functional annotation of circular RNAs using expression data	23
Skin in the game: a review of computational models of the skin	23
Neural network methods for diagnosing patient conditions from cardiopulmonary exercise testing data	19
Machine learning approaches to identify systemic lupus erythematosus in anti-nuclear antibody-positive patients using genomic data and electronic health records	17
Comparing new tools of artificial intelligence to the authentic intelligence of our global health students	17
Ten simple rules for providing bioinformatics support within a hospital	16
The biomedical knowledge graph of symptom phenotype in coronary artery plaque: machine learning-based analysis of real-world clinical data	15
Colorectal cancer subtype identification from differential gene expression levels using minimalist deep learning	15
Detection and classification of long terminal repeat sequences in plant LTR-retrotransposons and their analysis using explainable machine learning	13
Mapping the evolving trend of research on efferocytosis: a comprehensive data-mining-based study	12
Genetics and precision health: the ecological fallacy and artificial intelligence solutions	12
Gaussian noise up-sampling is better suited than SMOTE and ADASYN for clinical decision making	12
Decoding dynamic miRNA:ceRNA interactions unveils therapeutic insights and targets across predominant cancer landscapes	12
Supervised multiple kernel learning approaches for multi-omics data integration	11
m1A-Ensem: accurate identification of 1-methyladenosine sites through ensemble models	11

Using GPT-4 to write a scientific review article: a pilot evaluation study	11
Correction: Motif clustering and digital biomarker extraction for free-living physical activity analysis	11
Advancing preeclampsia prediction: a tailored machine learning pipeline integrating resampling and ensemble models for handling imbalanced medical data	11
Motif clustering and digital biomarker extraction for free-living physical activity analysis	10
From COVID-19 to monkeypox: a novel predictive model for emerging infectious diseases	10
Effective hybrid feature selection using different bootstrap enhances cancers classification performance	10
Predictive modeling of ALS progression: an XGBoost approach using clinical features	9
An unsupervised image segmentation algorithm for coronary angiography	9
Interpreting drug synergy in breast cancer with deep learning using target-protein inhibition profiles	9
Assessment of the causal relationship between gut microbiota and cardiovascular diseases: a bidirectional Mendelian randomization analysis	9
Machine learning models for reinjury risk prediction using cardiopulmonary exercise testing (CPET) data: optimizing athlete recovery	9
Understanding predictions of drug profiles using explainable machine learning models	9
Reference-free phylogeny from sequencing data	9
Detection of iron deficiency anemia by medical images: a comparative study of machine learning algorithms	8
Disclosing transcriptomics network-based signatures of glioma heterogeneity using sparse methods	8
Saliency-driven explainable deep learning in medical imaging: bridging visual explainability and statistical quantitative analysis	8
Ensemble feature selection and tabular data augmentation with generative adversarial networks to enhance cutaneous melanoma identification and interpretability	8
Deep learning-based Emergency Department In-hospital Cardiac Arrest Score (Deep EDICAS) for early prediction of cardiac arrest and cardiopulmonary resuscitation in the emergency department	7
6mA-StackingCV: an improved stacking ensemble model for predicting DNA N6-methyladenine site	7
Decoding ancestry-specific genetic risk: interpretable deep feature selection reveals prostate cancer SNP disparities in diverse populations	7
Humans and machines in biomedical knowledge curation: hypertrophic cardiomyopathy molecular mechanisms’ representation	7
A machine learning approach using conditional normalizing flow to address extreme class imbalance problems in personal health records	7
Open challenges and opportunities in federated foundation models towards biomedical healthcare	7
Optimizing age-related hearing risk predictions: an advanced machine learning integration with HHIE-S	6
Changing word meanings in biomedical literature reveal pandemics and new technologies	6
Identification of immune-associated biomarkers of diabetes nephropathy tubulointerstitial injury based on machine learning: a bioinformatics multi-chip integrated analysis	6
The Matthews correlation coefficient (MCC) should replace the ROC AUC as the standard metric for assessing binary classification	6
Endoscopy-based IBD identification by a quantized deep learning pipeline	5
TGNet: tensor-based graph convolutional networks for multimodal brain network analysis	5
Evaluation of network-guided random forest for disease gene discovery	5
Correction: A prognostic model based on seven immune-related genes predicts the overall survival of patients with hepatocellular carcinoma	5
Exo-Tox: Identifying Exotoxins from secreted bacterial proteins	5
Revealing third-order interactions through the integration of machine learning and entropy methods in genomic studies	5
ChatGPT and large language models in academia: opportunities and challenges	5
A Gated Recurrent Unit based architecture for recognizing ontology concepts from biological literature	5
MultiChem: predicting chemical properties using multi-view graph attention network	5
Machine learning based study for the classification of Type 2 diabetes mellitus subtypes	4
Integrating pathway knowledge with deep neural networks to reduce the dimensionality in single-cell RNA-seq data	4
The ethics of data mining in healthcare: challenges, frameworks, and future directions	4
ScInfoVAE: interpretable dimensional reduction of single cell transcription data with variational autoencoders and extended mutual information regularization	4
QIGTD: identifying critical genes in the evolution of lung adenocarcinoma with tensor decomposition	4
Polymorphisms in the mTOR-PI3K-Akt pathway, energy balance-related exposures and colorectal cancer risk in the Netherlands Cohort Study	4
Construction and application of medication reminder system: intelligent generation of universal medication schedule	4
Analysis of risk factors progression of preterm delivery using electronic health records	4
A regularized Cox hierarchical model for incorporating annotation information in predictive omic studies	4
Deciphering the tissue-specific functional effect of Alzheimer risk SNPs with deep genome annotation	4
Network-based multi-omics integrative analysis methods in drug discovery: a systematic review	4
Machine-learning-based models to predict cardiovascular risk using oculomics and clinic variables in KNHANES	4
Machine Learning Algorithms for understanding the determinants of under-five Mortality	4
Algorithm-based detection of acute kidney injury according to full KDIGO criteria including urine output following cardiac surgery: a descriptive analysis	4

subMG automates data submission for metagenomics studies	3
Cross-regional radiomics: a novel framework for relationship-based feature extraction with validation in Parkinson’s disease motor subtyping	3
AI as an accelerator for defining new problems that transcends boundaries	3
Novel digital approaches to the assessment of problematic opioid use	3
Short- and long-term weekly patient-reported outcomes prediction undergoing radiotherapy: single-patient time series model vs. transformer-based multi-patient time series model	3
ParticleChromo3D: a Particle Swarm Optimization algorithm for chromosome 3D structure prediction from Hi-C data	3
Electronic medical records imputation by temporal Generative Adversarial Network	3
Towards a potential pan-cancer prognostic signature for gene expression based on probesets and ensemble machine learning	3
Enhanced labor pain monitoring using machine learning and ECG waveform analysis for uterine contraction-induced pain	3
Enhancing hepatopathy clinical trial efficiency: a secure, large language model-powered pre-screening pipeline	3
Quantum analysis of squiggle data	3
PAGER: A novel genotype encoding strategy for modeling deviations from additivity in complex trait association studies	3
mSRFR: a machine learning model using microalgal signature features for ncRNA classification	3
Comparison of cancer subtype identification methods combined with feature selection methods in omics data analysis	3
Distinct network patterns emerge from Cartesian and XOR epistasis models: a comparative network science analysis	3
Priority-Elastic net for binary disease outcome prediction based on multi-omics data	3
iSuc-ChiDT: a computational method for identifying succinylation sites using statistical difference table encoding and the chi-square decision table classifier	2
Agenda setting for health equity assessment through the lenses of social determinants of health using machine learning approach: a framework and preliminary pilot study	2
Inverse problem for parameters identification in a modified SIRD epidemic model using ensemble neural networks	2
DIVIS: a semantic DIstance to improve the VISualisation of heterogeneous phenotypic datasets	2
Construction and validation of a machine learning-based model predicting early readmission in patients with decompensated cirrhosis: a prospective two-center cohort study	2
Private pathological assessment via machine learning and homomorphic encryption	2
Can open source large language models be used for tumor documentation in Germany?—An evaluation on urological doctors’ notes	2
Predicting molecular initiating events using chemical target annotations and gene expression	2
Assessing the limitations of relief-based algorithms in detecting higher-order interactions	2
Proteome mining of Yersinia Enterocolitica for drug targets and computational inhibitor identification with ADMET, anti-inflammation potential and formulation characteristics	2
Unsupervised encoding selection through ensemble pruning for biomedical classification	2
Correction to: iGlioSub: an integrative transcriptomic and epigenomic classifier for glioblastoma molecular subtypes	2
Overlapping filter bank convolutional neural network for multisubject multicategory motor imagery brain-computer interface	2
Leveraging mixed-effects regression trees for the analysis of high-dimensional longitudinal data to identify the low and high-risk subgroups: simulation study with application to genetic study	2
Influenza, dengue and common cold detection using LSTM with fully connected neural network and keywords selection	2
Automated quantitative trait locus analysis (AutoQTL)	2
Learning the therapeutic targets of acute myeloid leukemia through multiscale human interactome network and community analysis	2
Feature graphs for interpretable unsupervised tree ensembles: centrality, interaction, and application in disease subtyping	2
Prognostic feature based on androgen-responsive genes in bladder cancer and screening for potential targeted drugs	2
Correction: Predictive modeling of ALS progression: an XGBoost approach using clinical features	2
A deep learning approach for classifying and predicting children's nutritional status in Ethiopia using LSTM-FC neural networks	2
Deep learning-based approaches for multi-omics data integration and analysis	2