Molecular Brain

Article	Citations
FMRP binds Per1 mRNA and downregulates its protein expression in mice	83
Spatiotemporal Pavlovian head-fixed reversal learning task for mice	80
Correction to: Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity	57
Correction to: Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease	47
Knockout of AMPA receptor binding protein Neuron-specific gene 2 (NSG2) enhances associative learning and cognitive flexibility	43
Diurnal variation in declarative memory and the involvement of SCOP in cognitive functions in nonhuman primates	39
A novel mouse model for investigating α-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy	35
mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons	34
Protocadherin 19 regulates axon guidance in the developing Xenopus retinotectal pathway	32
Recent developments in peptide vaccines against Glioblastoma, a review and update	31
Inhibition of cortical synaptic transmission, behavioral nociceptive, and anxiodepressive-like responses by arecoline in adult mice	29
Chronic corticosterone exposure causes anxiety- and depression-related behaviors with altered gut microbial and brain metabolomic profiles in adult male C57BL/6J mice	29
New neurons in old brains: implications of age in the analysis of neurogenesis in post-mortem tissue	28
Broad proteomics analysis of seeding-induced aggregation of α-synuclein in M83 neurons reveals remodeling of proteostasis mechanisms that might contribute to Parkinson’s disease pathogenesis	27
Histamine H3 receptor inverse agonists/antagonists influence intra-regional cortical activity and inter-regional synchronization during resting state: an exploratory cortex-wide imaging study in mice	25
Impact of volume and expression time in an AAV-delivered channelrhodopsin	25
Chronic oral administration of ibrutinib prevents long-term memory deficits and reduces AD pathology and neuroinflammatory responses in a mouse model of AD	25
Correction: The deficiency of Maged1 attenuates Parkinson’s disease progression in mice	25
Role of autophagy in neurotoxic protein’s clearance following post-ischemic stroke: where we are and what we know?	24
AKAP6 controls NFATc4 activity for BDNF-mediated neuroprotection	24
Correction to: Synergistic actions of corticosterone and BDNF on rat hippocampal LTP	24
The brain cytokine orchestra in multiple sclerosis: from neuroinflammation to synaptopathology	22
Dynamic changes in the hippocampal neuronal circuits activity following acute stress revealed by miniature fluorescence microscopy imaging	22
Loss of Drosophila Coq8 results in impaired survival, locomotor deficits and photoreceptor degeneration	22
A simple and reliable method for claustrum localization across age in mice	22

Riluzole partially restores RNA polymerase III complex assembly in cells expressing the leukodystrophy-causative variant POLR3B R103H	21
Novelty-induced memory consolidation is accompanied by increased Agap3 transcription: a cross-species study	21
Chemogenetic activation of histamine neurons promotes retrieval of apparently lost memories	20
Involvement of posterior hypothalamic CaMKII-positive neurons in ADHD-like behaviors in mice	19
Sonic hedgehog signalling pathway in CNS tumours: its role and therapeutic implications	18
Olfactory receptor 78 is expressed in hypothalamic vasopressin/oxytocin neurons, parenchymal microglia and choroidal macrophages in mice	18
Post-conditioning sleep deprivation facilitates delay and trace fear memory extinction	18
Olfactory marker protein contains a leucine-rich domain in the Ω-loop important for nuclear export	17
Chronic pain enhances excitability of corticotropin-releasing factor-expressing neurons in the oval part of the bed nucleus of the stria terminalis	16
Subacute and chronic proteomic and phosphoproteomic analyses of a mouse model of traumatic brain injury at two timepoints and comparison with chronic traumatic encephalopathy in human samples	16
Selective enhancement of fear extinction by inhibiting neuronal adenylyl cyclase 1 (AC1) in aged mice	15
The terpenes alpha-bisabolol and camphene modulate pruritus via an action on Cav3.2 T-type calcium channels	15
Reduced activity of parvalbumin-positive interneurons in the posterior parietal cortex causes visually dominant multisensory decisions in freely navigating mice	15
VMAT2 availability in Parkinson’s disease with probable REM sleep behaviour disorder	14
Neurexin-3 in the paraventricular nucleus of the hypothalamus regulates body weight and glucose homeostasis independently of food intake	14
Impaired wakefulness and rapid eye movement sleep in dopamine-deficient mice	14
Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease	14
MeCP2 deficiency impairs motor cortical circuit flexibility associated with motor learning	14
The gut microbiota and metabolite profiles are altered in patients with spinal cord injury	14
Intravitreal injection of the Galectin-3 inhibitor TD139 provides neuroprotection in a rat model of ocular hypertensive glaucoma	13
Moxibustion ameliorates chronic inflammatory visceral pain via spinal circRNA-miRNA-mRNA networks: a central mechanism study	13
A new paradigm of learned cooperation reveals extensive social coordination and specific cortical activation in mice	13
Increased social interaction in Shank2-deficient mice following acute social isolation	13
Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD	12
A natural marmoset model of genetic generalized epilepsy	12
Pathophysiology of ion channels in amyotrophic lateral sclerosis	12
TREM2 improves microglia function and synaptic development in autism spectrum disorders by regulating P38 MAPK signaling pathway	12
Sonication dissociates the synaptic cleft and allows purification of postsynaptic densities with associated postsynaptic membrane	12
Region-specific activation in the accumbens nucleus by itch with modified scratch efficacy in mice – a model-free multivariate analysis	12
mTORC1 function in hippocampal parvalbumin interneurons: regulation of firing and long-term potentiation of intrinsic excitability but not long-term contextual fear memory and context discrimination	12
Novelty triggers time-dependent theta oscillatory dynamics in cortical-hippocampal-midbrain circuitry	12
Spermidine treatment: induction of autophagy but also apoptosis?	12
Toll-like receptors and their role in neuropathic pain and migraine	11
NEK7 induces lactylation in Alzheimer’s disease to promote pyroptosis in BV-2 cells	11
Repeated naloxone-induced morphine withdrawal alters blood brain barrier and blood spinal cord barrier integrity in mice	11
Chronic skin ultraviolet irradiation induces transcriptomic changes associated with microglial dysfunction in the hippocampus	11
Elucidation of the mechanisms underlying tumor aggravation by the activation of stress-related neurons in the paraventricular nucleus of the hypothalamus	11
Spinal microglia contribute to sustained inflammatory pain via amplifying neuronal activity	11
High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression	11
Changes in oligodendroglial subpopulations in Parkinson’s disease	11
Neuropathological and behavioral features of an APP/PS1/MAPT (6xTg) transgenic model of Alzheimer’s disease	11
Activation of angiotensin-converting enzyme 2 produces an antidepressant-like effect via MAS receptors in mice	10
Correction: Extinction of contextual fear memory is facilitated in TRPM2 knockout mice	10
A new AAV tool for highly preferentially targeting hippocampal CA2	10
Genetic deletion of nitric oxide synthase 2 ameliorates Parkinson’s disease pathology and neuroinflammation in a transgenic mouse model of synucleinopathy	10
Correction: Requirement for hippocampal CA3 NMDA receptors in artificial association of memory events stored in CA3 cell ensembles	10
Astrocytic activation increases blood flow in the adult olfactory bulb	10
Generation of a new Slc20a2 knockout mouse line as in vivo model for primary brain calcification	10
Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state	10
Limitations of the human iPSC-derived neuron model for early-onset Alzheimer’s disease	10

Nek6 regulates autophagy through the mTOR signaling pathway to alleviate cerebral ischemia–reperfusion injury	10
Acupuncture improves depressive-like behaviors in CUMS rats by modulating lateral habenula synaptic plasticity via the BDNF/ERK/mTOR pathway	10
Crucial role of TFAP2B in the nervous system for regulating NREM sleep	10
Integrated genomic and DNA methylation analysis of patients with advanced non-small cell lung cancer with brain metastases	10
Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons	9
Age-related attenuation of cortical synaptic tagging in the ACC is rescued by BDNF or a TrkB receptor agonist in both sex of mice	9
Synergistic actions of corticosterone and BDNF on rat hippocampal LTP	9
The absence of Neuroligin-1 shapes wake/sleep architecture, rhythmic and arrhythmic activities of the electrocorticogram in female mice	9
Analysis of neurexin-neuroligin complexes supports an isoform-specific role for beta-neurexin-1 dysfunction in a mouse model of autism	9
Neurexin-1-dependent circuit activity is required for the maintenance of photoreceptor subtype identity in Drosophila	9
Hypothalamic protein profiling from mice subjected to social defeat stress	9
Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation	9
The adaptor protein PICK1 targets the sorting receptor SorLA	9
Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism	9
Behavioral phenotype, intestinal microbiome, and brain neuronal activity of male serotonin transporter knockout mice	9
Experience-dependent changes in affective valence of taste in male mice	9
Inhibitory insula-ACC projections modulate affective but not sensory aspects of neuropathic pain	8
Effects of intermittent theta burst stimulation on the inflammatory response and cerebral blood flow in promoting neurovascular repair after ischemic stroke	8
Peripheral-central network analysis of cancer cachexia status accompanied by the polarization of hypothalamic microglia with low expression of inhibitory immune checkpoint receptors	8
Changes in the pH value of the human brain in Alzheimer’s disease pathology correlated with CD68-positive microglia: a community-based autopsy study in Beijing, China	8
PV-IRES-Cre mouse line targets excitatory granule neurons in the cerebellum	8
Outer layer of Vb neurons in medial entorhinal cortex project to hippocampal dentate gyrus in mice	8
The cyclin G-associated kinase (GAK) inhibitor SGC-GAK-1 inhibits neurite outgrowth and synapse formation	7
Acute social defeat stress activated neurons project to the claustrum and basolateral amygdala	7
Deleting IP6K1 stabilizes neuronal sodium–potassium pumps and suppresses excitability	7
Circadian cilia transcriptome in mouse brain across physiological and pathological states	7
Targeted NMDA receptor knockdown in recall‐activated neuronal ensembles impairs remote fear extinction	7
Mechanisms of glutamate receptors hypofunction dependent synaptic transmission impairment in the hippocampus of schizophrenia susceptibility gene Opcml-deficient mouse model	7
Locus specific reduction of L1 expression in the cortices of individuals with amyotrophic lateral sclerosis	7
Sleep-driven prefrontal cortex coordinates temporal action and multimodal integration	7
Regulation of dendritic spine length in corticopontine layer V pyramidal neurons by autism risk gene β3 integrin	7
Temporal pain processing in the primary somatosensory cortex and anterior cingulate cortex	7
Astrocyte-derived dominance winning reverses chronic stress-induced depressive behaviors	7
Cavβ surface charged residues contribute to the regulation of neuronal calcium channels	7
Proteasome inhibition suppresses the induction of lipocalin-2 upon systemic lipopolysaccharide challenge in mice	7
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection	7
The medial prefrontal cortex encodes procedural rules as sequential neuronal activity dynamics	7
Quercetin carbon quantum dots: dual-target therapy for intracerebral hemorrhage in mice	7
Function of KCNQ2 channels at nodes of Ranvier of lumbar spinal ventral nerves of rats	7
Decreased in vivo glutamate/GABA ratio correlates with the social behavior deficit in a mouse model of autism spectrum disorder	7
Hes5+ astrocytes potentiate primary afferent Aδ and C fiber-mediated excitatory synaptic transmission to spinal lamina I neurons	7
Knockdown of myorg leads to brain calcification in zebrafish	6
Neural stem cell-specific deletion of Atg7 alleviates hippocampal dysfunction and neuronal alterations induced by chronic restraint stress	6
Postmortem gene expression profiles in the habenulae of suicides: implication of endothelial dysfunction in the neurovascular system	6
14-3-3γ haploinsufficiency leads to altered dopamine pathway and Parkinson’s disease-like motor incoordination in mice	6
CSF Amyloid-β42 associates with neuropsychiatric and cognitive outcomes via cerebral glucose metabolism	6
Modulating and monitoring the functionality of corticostriatal circuits using an electrostimulable microfluidic device	6
Voluntary running improves synaptic degeneration of the anterior cingulate cortex in knee osteoarthritis	6
BCAT1 controls embryonic neural stem cells proliferation and differentiation in the upper layer neurons	6
Retina-attached slice recording reveals light-triggered tonic GABA signaling in suprachiasmatic nucleus	6
Brain region networks for the assimilation of new associative memory into a schema	6
Blood–brain barrier: emerging trends on transport models and new-age strategies for therapeutics intervention against neurological disorders	6
Prior episode of colitis impairs contextual fear memory	6
Correction: The properties of TREM1 and its emerging role in pain-related diseases	6
Spatiotemporal expression patterns of genes coding for plasmalemmal chloride transporters and channels in neurological diseases	6
Development of Cre-dependent retrograde trans-multisynaptic tracer based on pseudorabies virus bartha strain	5
Felodipine attenuates neuroinflammatory responses and tau hyperphosphorylation through JNK/P38 signaling in tau-overexpressing AD mice	5
Maturation of nucleus accumbens synaptic transmission signals a critical period for the rescue of social deficits in a mouse model of autism spectrum disorder	5
Distinct neural responses of ventromedial prefrontal cortex-projecting nucleus reuniens neurons during aversive memory extinction	5
Hif1α-dependent hypoxia signaling contributes to the survival of deep-layer neurons and cortex formation in a mouse model	5
Globus pallidus is not independent from striatal direct pathway neurons: an up-to-date review	5
Ultrastructural characterization of hippocampal inhibitory synapses under resting and stimulated conditions	5
Visualization of the existence of growth hormone secretagogue receptor in the rat nucleus accumbens	5
Tyrosine phosphatase STEP61 in human dementia and in animal models with amyloid and tau pathology	5
A large-scale polygenic risk score analysis identified candidate proteins associated with anxiety, depression and neuroticism	5
Distribution of five clinically important neuroglial proteins in the human brain	5
Running-induced neurogenesis reduces CA1 perineuronal net density without substantial temporal delay	5
Enhanced synchronization between prelimbic and infralimbic cortices during fear extinction learning	5
Genome-wide translation control analysis of developing human neurons	5
Epigenetic signature of N-terminal acetyltransferases: a probable mediator of immune and neuropathogenesis in HIV infection	5
Characterization of exosome-mediated propagation of systemic inflammatory responses into the central nervous system	5
DYRK1A modulates fear memory formation via epigenetic modification	5
Homocysteine enhances the excitability of cultured hippocampal neurons without altering the gene expression of voltage-gated ion channels	5
Olfactory marker protein is unlikely to be cleaved by calpain 5	5
Ameliorative effects of Fingolimod (FTY720) on microglial activation and psychosis-related behavior in short term cuprizone exposed mice	5
Dihydroartemisinin attenuates hypoxic-ischemic brain damage in neonatal rats by inhibiting oxidative stress	5
Chemogenetic silencing of the subiculum blocks acute chronic temporal lobe epilepsy	4
In vitro modulation of mTOR and mGlur5 influence α-synuclein accumulation	4
Development of a novel peptide to prevent entry of SARS-CoV-2 into lung and olfactory bulb cells of hACE2 expressing mice	4
Cerebellar damage with inflammation upregulates oxytocin receptor expression in Bergmann Glia	4

Properties of Nav1.8ChR2-positive and Nav1.8ChR2-negative afferent mechanoreceptors in the hindpaw glabrous skin of mice	4
Analgesia by intrathecal delta-9-tetrahydrocannabinol is dependent on Cav3.2 calcium channels	4
Cell-line dependency in cerebral organoid induction: cautionary observations in Alzheimer’s disease patient-derived induced pluripotent stem cells	4
Correction to: Oxytocin ameliorates impaired social behavior in a mouse model of 3q29 deletion syndrome	4
Antihyperalgesic effect of joint mobilization requires Cav3.2 calcium channels	4
Involvement of muscarinic receptors in psychomotor hyperactivity in dopamine-deficient mice	4
Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE)	4
Burst firing is required for induction of Hebbian LTP at lateral perforant path to hippocampal granule cell synapses	4
Paraventricular hypothalamic vasopressin neurons induce self-grooming in mice	4
Optogenetic activation of dopamine D1 receptors in island cells of medial entorhinal cortex inhibits temporal association learning	4
Integrated molecular data analysis confirms PDK1 as a candidate risk factor in ALS pathophysiology	4
Cortical pain induced by optogenetic cortical spreading depression: from whole brain activity mapping	4
Deoxyhypusine synthase deficiency syndrome zebrafish model: aberrant morphology, epileptiform activity, and reduced arborization of inhibitory interneurons	4
Comprehensive behavioral analyses of mice with a glycine receptor alpha 4 deficiency	4
Extinction of contextual fear memory is facilitated in TRPM2 knockout mice	4
Microtubule-associated protein 1 A and tubby act independently in regulating the localization of stereocilin to the tips of inner ear hair cell stereocilia	4
A structural analysis of the splice-specific functional impact of the pathogenic familial hemiplegic migraine type 1 S218L mutation on Cav2.1 P/Q-type channel gating	4
Functional characterization of a novel de novo CACNA1C pathogenic variant in a patient with neurodevelopmental disorder	4
Improving working memory by electrical stimulation and cross-frequency coupling	4
Antiallodynic effects of KDS2010, a novel MAO-B inhibitor, via ROS-GABA inhibitory transmission in a paclitaxel-induced tactile hypersensitivity model	4
Roles of mediodorsal thalamus in observational fear-related neural activity in mouse anterior cingulate cortex	4
Modifiable risk factors that mediate the effect of educational attainment on the risk of stroke: a network Mendelian randomization study	4
Divergent disruptive effects of soluble recombinant tau assemblies on synaptic plasticity in vivo	4
Virally mediated expression of a biologically active peptide to restrain the nuclear functions of ERK1/2 attenuates learning extinction but not acquisition	4
Transient inhibition of microsomal prostaglandin E synthase-1 after status epilepticus blunts brain inflammation and is neuroprotective	4
Peripheral substance P induces deficits in hippocampal synaptic plasticity and memory	3
Identification of VGLUT3-expressing LTMRs-recruited spinal circuits for itch inhibition	3
CaVβ-subunit dependence of forward and reverse trafficking of CaV1.2 calcium channels	3
Object location learning in mice requires hippocampal somatostatin interneuron activity and is facilitated by mTORC1-mediated long-term potentiation of their excitatory synapses	3
Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease	3
C1ql1-Bai3 signaling is necessary for climbing fiber synapse formation in mature Purkinje cells in coordination with neuronal activity	3
Intravenous infusion of mesenchymal stem cells increased axonal signal intensity in the rubrospinal tract in spinal cord injury	3
Genome-wide analysis of genes encoding core components of the ubiquitin system during cerebral cortex development	3
Electroacupuncture reduces inflammatory damage following cerebral ischemia–reperfusion by enhancing ABCA1-mediated efferocytosis in M2 microglia	3
β-hydroxybutyrate and ischemic stroke: roles and mechanisms	3
The deficiency of Maged1 attenuates Parkinson's disease progression in mice	3
Exploration of new space elicits phosphorylation of GluA1(Ser831) and S6K and expression of Arc in the hippocampus in vivo as in long-term potentiation	3
Systemic injection of nicotinic acetylcholine receptor antagonist mecamylamine affects licking, eyelid size, and locomotor and autonomic activities but not temporal prediction in male mice	3
Ablation of microglia does not alter circadian rhythm of locomotor activity	3
Stimulation of protein synthesis by optogenetic and chemical induction of excitatory synaptic plasticity in hippocampal somatostatin interneurons	3
Reactive astrocytes mediate TSPO overexpression in response to sustained CNTF exposure in the rat striatum	3
Surgery impairs glymphatic activity and cognitive function in aged mice	3
Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat	3
Exploring Piezo1, Piezo2, and TMEM150C in human brain tissues and their correlation with brain biomechanical characteristics	3
GAS reduced inflammatory responses in activated microglia by regulating the Ccr2/Akt/Gsk-3β pathway	3