Molecular Brain

Article	Citations
Knockout of AMPA receptor binding protein Neuron-specific gene 2 (NSG2) enhances associative learning and cognitive flexibility	79
FMRP binds Per1 mRNA and downregulates its protein expression in mice	59
Spatiotemporal Pavlovian head-fixed reversal learning task for mice	54
Broad proteomics analysis of seeding-induced aggregation of α-synuclein in M83 neurons reveals remodeling of proteostasis mechanisms that might contribute to Parkinson’s disease pathogenesis	52
Correction to: Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease	44
Correction to: Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity	43
Recent developments in peptide vaccines against Glioblastoma, a review and update	43
Protocadherin 19 regulates axon guidance in the developing Xenopus retinotectal pathway	39
mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons	35
A novel mouse model for investigating α-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy	35
New neurons in old brains: implications of age in the analysis of neurogenesis in post-mortem tissue	35
Diurnal variation in declarative memory and the involvement of SCOP in cognitive functions in nonhuman primates	33
Chronic corticosterone exposure causes anxiety- and depression-related behaviors with altered gut microbial and brain metabolomic profiles in adult male C57BL/6J mice	33
Inhibition of cortical synaptic transmission, behavioral nociceptive, and anxiodepressive-like responses by arecoline in adult mice	32
Arginine vasopressin in the medial amygdala causes greater post-stress recruitment of hypothalamic vasopressin neurons	30
AKAP6 controls NFATc4 activity for BDNF-mediated neuroprotection	30
Role of autophagy in neurotoxic protein’s clearance following post-ischemic stroke: where we are and what we know?	28
The brain cytokine orchestra in multiple sclerosis: from neuroinflammation to synaptopathology	26
Correction: The deficiency of Maged1 attenuates Parkinson’s disease progression in mice	26
Impact of volume and expression time in an AAV-delivered channelrhodopsin	26
Loss of Drosophila Coq8 results in impaired survival, locomotor deficits and photoreceptor degeneration	24
Correction to: Synergistic actions of corticosterone and BDNF on rat hippocampal LTP	24
A simple and reliable method for claustrum localization across age in mice	24
Chronic oral administration of ibrutinib prevents long-term memory deficits and reduces AD pathology and neuroinflammatory responses in a mouse model of AD	24
Dynamic changes in the hippocampal neuronal circuits activity following acute stress revealed by miniature fluorescence microscopy imaging	24

Histamine H3 receptor inverse agonists/antagonists influence intra-regional cortical activity and inter-regional synchronization during resting state: an exploratory cortex-wide imaging study in mice	23
Riluzole partially restores RNA polymerase III complex assembly in cells expressing the leukodystrophy-causative variant POLR3B R103H	22
Chemogenetic activation of histamine neurons promotes retrieval of apparently lost memories	22
Involvement of posterior hypothalamic CaMKII-positive neurons in ADHD-like behaviors in mice	22
Sonic hedgehog signalling pathway in CNS tumours: its role and therapeutic implications	22
Olfactory receptor 78 is expressed in hypothalamic vasopressin/oxytocin neurons, parenchymal microglia and choroidal macrophages in mice	21
Nanoscale organization of Nicastrin, the substrate receptor of the γ-secretase complex, as independent molecular domains	20
Novelty-induced memory consolidation is accompanied by increased Agap3 transcription: a cross-species study	20
Chronic pain enhances excitability of corticotropin-releasing factor-expressing neurons in the oval part of the bed nucleus of the stria terminalis	20
Post-conditioning sleep deprivation facilitates delay and trace fear memory extinction	20
Olfactory marker protein contains a leucine-rich domain in the Ω-loop important for nuclear export	19
Electroacupuncture improves repeated social defeat stress-elicited social avoidance and anxiety-like behaviors by reducing Lipocalin-2 in the hippocampus	19
Subacute and chronic proteomic and phosphoproteomic analyses of a mouse model of traumatic brain injury at two timepoints and comparison with chronic traumatic encephalopathy in human samples	18
The terpenes alpha-bisabolol and camphene modulate pruritus via an action on Cav3.2 T-type calcium channels	18
Reduced activity of parvalbumin-positive interneurons in the posterior parietal cortex causes visually dominant multisensory decisions in freely navigating mice	18
Selective enhancement of fear extinction by inhibiting neuronal adenylyl cyclase 1 (AC1) in aged mice	17
MeCP2 deficiency impairs motor cortical circuit flexibility associated with motor learning	17
VMAT2 availability in Parkinson’s disease with probable REM sleep behaviour disorder	17
Impaired wakefulness and rapid eye movement sleep in dopamine-deficient mice	16
A new paradigm of learned cooperation reveals extensive social coordination and specific cortical activation in mice	16
Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease	15
Increased social interaction in Shank2-deficient mice following acute social isolation	14
Moxibustion ameliorates chronic inflammatory visceral pain via spinal circRNA-miRNA-mRNA networks: a central mechanism study	14
Intravitreal injection of the Galectin-3 inhibitor TD139 provides neuroprotection in a rat model of ocular hypertensive glaucoma	14
Neurexin-3 in the paraventricular nucleus of the hypothalamus regulates body weight and glucose homeostasis independently of food intake	14
The gut microbiota and metabolite profiles are altered in patients with spinal cord injury	14
Novelty triggers time-dependent theta oscillatory dynamics in cortical-hippocampal-midbrain circuitry	13
Pathophysiology of ion channels in amyotrophic lateral sclerosis	13
Region-specific activation in the accumbens nucleus by itch with modified scratch efficacy in mice – a model-free multivariate analysis	13
Spermidine treatment: induction of autophagy but also apoptosis?	13
A natural marmoset model of genetic generalized epilepsy	13
Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD	12
Sonication dissociates the synaptic cleft and allows purification of postsynaptic densities with associated postsynaptic membrane	12
Comparative metabolic profiling of posterior parietal cortex, amygdala, and hippocampus in conditioned fear memory	12
Changes in oligodendroglial subpopulations in Parkinson’s disease	12
Toll-like receptors and their role in neuropathic pain and migraine	12
Selectively increasing GHS-R1a expression in dCA1 excitatory/inhibitory neurons have opposite effects on memory encoding	12
mTORC1 function in hippocampal parvalbumin interneurons: regulation of firing and long-term potentiation of intrinsic excitability but not long-term contextual fear memory and context discrimination	11
Repeated naloxone-induced morphine withdrawal alters blood brain barrier and blood spinal cord barrier integrity in mice	11
Spinal microglia contribute to sustained inflammatory pain via amplifying neuronal activity	11
Genetic deletion of nitric oxide synthase 2 ameliorates Parkinson’s disease pathology and neuroinflammation in a transgenic mouse model of synucleinopathy	11
Chronic skin ultraviolet irradiation induces transcriptomic changes associated with microglial dysfunction in the hippocampus	11
Elucidation of the mechanisms underlying tumor aggravation by the activation of stress-related neurons in the paraventricular nucleus of the hypothalamus	11
TREM2 improves microglia function and synaptic development in autism spectrum disorders by regulating P38 MAPK signaling pathway	11
Integrated genomic and DNA methylation analysis of patients with advanced non-small cell lung cancer with brain metastases	11
Neuropathological and behavioral features of an APP/PS1/MAPT (6xTg) transgenic model of Alzheimer’s disease	11
High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression	11
Activation of angiotensin-converting enzyme 2 produces an antidepressant-like effect via MAS receptors in mice	11
NEK7 induces lactylation in Alzheimer’s disease to promote pyroptosis in BV-2 cells	11
Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state	11

Crucial role of TFAP2B in the nervous system for regulating NREM sleep	10
Correction: Extinction of contextual fear memory is facilitated in TRPM2 knockout mice	10
Brain-derived neurotrophic factor produced long-term synaptic enhancement in the anterior cingulate cortex of adult mice	10
The adaptor protein PICK1 targets the sorting receptor SorLA	10
Analysis of neurexin-neuroligin complexes supports an isoform-specific role for beta-neurexin-1 dysfunction in a mouse model of autism	10
Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism	10
A new AAV tool for highly preferentially targeting hippocampal CA2	10
Astrocytic activation increases blood flow in the adult olfactory bulb	10
Correction: Requirement for hippocampal CA3 NMDA receptors in artificial association of memory events stored in CA3 cell ensembles	10
Nek6 regulates autophagy through the mTOR signaling pathway to alleviate cerebral ischemia–reperfusion injury	10
Limitations of the human iPSC-derived neuron model for early-onset Alzheimer’s disease	10
Splice-variant specific effects of a CACNA1H mutation associated with writer’s cramp	10
Generation of a new Slc20a2 knockout mouse line as in vivo model for primary brain calcification	9
Experience-dependent changes in affective valence of taste in male mice	9
The absence of Neuroligin-1 shapes wake/sleep architecture, rhythmic and arrhythmic activities of the electrocorticogram in female mice	9
PV-IRES-Cre mouse line targets excitatory granule neurons in the cerebellum	9
Behavioral phenotype, intestinal microbiome, and brain neuronal activity of male serotonin transporter knockout mice	9
Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons	9
Neurexin-1-dependent circuit activity is required for the maintenance of photoreceptor subtype identity in Drosophila	9
Hypoxia with inflammation and reperfusion alters membrane resistance by dynamically regulating voltage-gated potassium channels in hippocampal CA1 neurons	9
Age-related attenuation of cortical synaptic tagging in the ACC is rescued by BDNF or a TrkB receptor agonist in both sex of mice	9
Hypothalamic protein profiling from mice subjected to social defeat stress	9
Peripheral-central network analysis of cancer cachexia status accompanied by the polarization of hypothalamic microglia with low expression of inhibitory immune checkpoint receptors	9
Synergistic actions of corticosterone and BDNF on rat hippocampal LTP	9
Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation	9
Acute social defeat stress activated neurons project to the claustrum and basolateral amygdala	8
Inhibitory insula-ACC projections modulate affective but not sensory aspects of neuropathic pain	8
Regulation of dendritic spine length in corticopontine layer V pyramidal neurons by autism risk gene β3 integrin	8
Minhee Analysis Package: an integrated software package for detection and management of spontaneous synaptic events	8
Changes in the pH value of the human brain in Alzheimer’s disease pathology correlated with CD68-positive microglia: a community-based autopsy study in Beijing, China	8
Quercetin carbon quantum dots: dual-target therapy for intracerebral hemorrhage in mice	8
The medial prefrontal cortex encodes procedural rules as sequential neuronal activity dynamics	8
Outer layer of Vb neurons in medial entorhinal cortex project to hippocampal dentate gyrus in mice	8
Targeted NMDA receptor knockdown in recall‐activated neuronal ensembles impairs remote fear extinction	8
Effects of intermittent theta burst stimulation on the inflammatory response and cerebral blood flow in promoting neurovascular repair after ischemic stroke	8
Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply	7
Temporal pain processing in the primary somatosensory cortex and anterior cingulate cortex	7
Proteasome inhibition suppresses the induction of lipocalin-2 upon systemic lipopolysaccharide challenge in mice	7
Hes5+ astrocytes potentiate primary afferent Aδ and C fiber-mediated excitatory synaptic transmission to spinal lamina I neurons	7
Mechanisms of glutamate receptors hypofunction dependent synaptic transmission impairment in the hippocampus of schizophrenia susceptibility gene Opcml-deficient mouse model	7
Locus specific reduction of L1 expression in the cortices of individuals with amyotrophic lateral sclerosis	7
Sleep-driven prefrontal cortex coordinates temporal action and multimodal integration	7
Deleting IP6K1 stabilizes neuronal sodium–potassium pumps and suppresses excitability	7
The phosphorylation status of eukaryotic elongation factor-2 indicates neural activity in the brain	7
Circadian cilia transcriptome in mouse brain across physiological and pathological states	7
Function of KCNQ2 channels at nodes of Ranvier of lumbar spinal ventral nerves of rats	7
Cavβ surface charged residues contribute to the regulation of neuronal calcium channels	7
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection	6
Prior episode of colitis impairs contextual fear memory	6
Neural stem cell-specific deletion of Atg7 alleviates hippocampal dysfunction and neuronal alterations induced by chronic restraint stress	6
The cyclin G-associated kinase (GAK) inhibitor SGC-GAK-1 inhibits neurite outgrowth and synapse formation	6
CSF Amyloid-β42 associates with neuropsychiatric and cognitive outcomes via cerebral glucose metabolism	6
Correction: The properties of TREM1 and its emerging role in pain-related diseases	6
Distribution of five clinically important neuroglial proteins in the human brain	6
Decreased in vivo glutamate/GABA ratio correlates with the social behavior deficit in a mouse model of autism spectrum disorder	6
Rapid generation of conditional knockout mice using the CRISPR-Cas9 system and electroporation for neuroscience research	6
Brain region networks for the assimilation of new associative memory into a schema	6
Voluntary running improves synaptic degeneration of the anterior cingulate cortex in knee osteoarthritis	6
BCAT1 controls embryonic neural stem cells proliferation and differentiation in the upper layer neurons	6
Homocysteine enhances the excitability of cultured hippocampal neurons without altering the gene expression of voltage-gated ion channels	6
Postmortem gene expression profiles in the habenulae of suicides: implication of endothelial dysfunction in the neurovascular system	6
Astrocyte-derived dominance winning reverses chronic stress-induced depressive behaviors	6
Knockdown of myorg leads to brain calcification in zebrafish	6
Modulating and monitoring the functionality of corticostriatal circuits using an electrostimulable microfluidic device	6
Blood–brain barrier: emerging trends on transport models and new-age strategies for therapeutics intervention against neurological disorders	6
Spatiotemporal expression patterns of genes coding for plasmalemmal chloride transporters and channels in neurological diseases	6
Retina-attached slice recording reveals light-triggered tonic GABA signaling in suprachiasmatic nucleus	6
Visualization of the existence of growth hormone secretagogue receptor in the rat nucleus accumbens	5
Tyrosine phosphatase STEP61 in human dementia and in animal models with amyloid and tau pathology	5
DYRK1A modulates fear memory formation via epigenetic modification	5
Hif1α-dependent hypoxia signaling contributes to the survival of deep-layer neurons and cortex formation in a mouse model	5
Felodipine attenuates neuroinflammatory responses and tau hyperphosphorylation through JNK/P38 signaling in tau-overexpressing AD mice	5
Ameliorative effects of Fingolimod (FTY720) on microglial activation and psychosis-related behavior in short term cuprizone exposed mice	5
Association of CaMK2A and MeCP2 signaling pathways with cognitive ability in adolescents	5
Olfactory marker protein is unlikely to be cleaved by calpain 5	5
A large-scale polygenic risk score analysis identified candidate proteins associated with anxiety, depression and neuroticism	5
Characterization of exosome-mediated propagation of systemic inflammatory responses into the central nervous system	5
14-3-3γ haploinsufficiency leads to altered dopamine pathway and Parkinson’s disease-like motor incoordination in mice	5
Distinct neural responses of ventromedial prefrontal cortex-projecting nucleus reuniens neurons during aversive memory extinction	5
Maturation of nucleus accumbens synaptic transmission signals a critical period for the rescue of social deficits in a mouse model of autism spectrum disorder	5

Globus pallidus is not independent from striatal direct pathway neurons: an up-to-date review	5
Genome-wide translation control analysis of developing human neurons	5
Ultrastructural characterization of hippocampal inhibitory synapses under resting and stimulated conditions	5
Development of Cre-dependent retrograde trans-multisynaptic tracer based on pseudorabies virus bartha strain	5
Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain	5
Similarities of developmental gene expression changes in the brain between human and experimental animals: rhesus monkey, mouse, Zebrafish, and Drosophila	5
Running-induced neurogenesis reduces CA1 perineuronal net density without substantial temporal delay	5
Enhanced synchronization between prelimbic and infralimbic cortices during fear extinction learning	5
Dihydroartemisinin attenuates hypoxic-ischemic brain damage in neonatal rats by inhibiting oxidative stress	5
Divergent disruptive effects of soluble recombinant tau assemblies on synaptic plasticity in vivo	4
Burst firing is required for induction of Hebbian LTP at lateral perforant path to hippocampal granule cell synapses	4
Paraventricular hypothalamic vasopressin neurons induce self-grooming in mice	4
Chemogenetic silencing of the subiculum blocks acute chronic temporal lobe epilepsy	4
Correction to: Oxytocin ameliorates impaired social behavior in a mouse model of 3q29 deletion syndrome	4
Development of a novel peptide to prevent entry of SARS-CoV-2 into lung and olfactory bulb cells of hACE2 expressing mice	4
Epigenetic signature of N-terminal acetyltransferases: a probable mediator of immune and neuropathogenesis in HIV infection	4
Antiallodynic effects of KDS2010, a novel MAO-B inhibitor, via ROS-GABA inhibitory transmission in a paclitaxel-induced tactile hypersensitivity model	4
Ackr3-Venus knock-in mouse lights up brain vasculature	4
Microtubule-associated protein 1 A and tubby act independently in regulating the localization of stereocilin to the tips of inner ear hair cell stereocilia	4
Comprehensive behavioral analyses of mice with a glycine receptor alpha 4 deficiency	4
Antihyperalgesic effect of joint mobilization requires Cav3.2 calcium channels	4
Cerebellar damage with inflammation upregulates oxytocin receptor expression in Bergmann Glia	4
Transient inhibition of microsomal prostaglandin E synthase-1 after status epilepticus blunts brain inflammation and is neuroprotective	4
Cortical pain induced by optogenetic cortical spreading depression: from whole brain activity mapping	4
Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease	4
Modifiable risk factors that mediate the effect of educational attainment on the risk of stroke: a network Mendelian randomization study	4
Functional characterization of a novel de novo CACNA1C pathogenic variant in a patient with neurodevelopmental disorder	4
Cell-line dependency in cerebral organoid induction: cautionary observations in Alzheimer’s disease patient-derived induced pluripotent stem cells	4
Involvement of muscarinic receptors in psychomotor hyperactivity in dopamine-deficient mice	4
Deoxyhypusine synthase deficiency syndrome zebrafish model: aberrant morphology, epileptiform activity, and reduced arborization of inhibitory interneurons	4
Roles of mediodorsal thalamus in observational fear-related neural activity in mouse anterior cingulate cortex	4
Analgesia by intrathecal delta-9-tetrahydrocannabinol is dependent on Cav3.2 calcium channels	4
A structural analysis of the splice-specific functional impact of the pathogenic familial hemiplegic migraine type 1 S218L mutation on Cav2.1 P/Q-type channel gating	4
Virally mediated expression of a biologically active peptide to restrain the nuclear functions of ERK1/2 attenuates learning extinction but not acquisition	4
Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat	3
Properties of Nav1.8ChR2-positive and Nav1.8ChR2-negative afferent mechanoreceptors in the hindpaw glabrous skin of mice	3
Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition	3
Improving working memory by electrical stimulation and cross-frequency coupling	3
Exploration of new space elicits phosphorylation of GluA1(Ser831) and S6K and expression of Arc in the hippocampus in vivo as in long-term potentiation	3
Stimulation of protein synthesis by optogenetic and chemical induction of excitatory synaptic plasticity in hippocampal somatostatin interneurons	3
Systemic injection of nicotinic acetylcholine receptor antagonist mecamylamine affects licking, eyelid size, and locomotor and autonomic activities but not temporal prediction in male mice	3
C1ql1-Bai3 signaling is necessary for climbing fiber synapse formation in mature Purkinje cells in coordination with neuronal activity	3
Assessing the effect of interaction between C-reactive protein and gut microbiome on the risks of anxiety and depression	3
Optogenetic activation of dopamine D1 receptors in island cells of medial entorhinal cortex inhibits temporal association learning	3
In vitro modulation of mTOR and mGlur5 influence α-synuclein accumulation	3
The deficiency of Maged1 attenuates Parkinson's disease progression in mice	3
Ablation of microglia does not alter circadian rhythm of locomotor activity	3
Electroacupuncture reduces inflammatory damage following cerebral ischemia–reperfusion by enhancing ABCA1-mediated efferocytosis in M2 microglia	3
Reactive astrocytes mediate TSPO overexpression in response to sustained CNTF exposure in the rat striatum	3
Object location learning in mice requires hippocampal somatostatin interneuron activity and is facilitated by mTORC1-mediated long-term potentiation of their excitatory synapses	3
Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE)	3
Extinction of contextual fear memory is facilitated in TRPM2 knockout mice	3
CaVβ-subunit dependence of forward and reverse trafficking of CaV1.2 calcium channels	3
Surgery impairs glymphatic activity and cognitive function in aged mice	3
GAS reduced inflammatory responses in activated microglia by regulating the Ccr2/Akt/Gsk-3β pathway	3
β-hydroxybutyrate and ischemic stroke: roles and mechanisms	3
Exploring Piezo1, Piezo2, and TMEM150C in human brain tissues and their correlation with brain biomechanical characteristics	3