Molecular Brain

Article	Citations
Diurnal variation in declarative memory and the involvement of SCOP in cognitive functions in nonhuman primates	67
Knockout of AMPA receptor binding protein Neuron-specific gene 2 (NSG2) enhances associative learning and cognitive flexibility	51
Spatiotemporal Pavlovian head-fixed reversal learning task for mice	43
FMRP binds Per1 mRNA and downregulates its protein expression in mice	43
Broad proteomics analysis of seeding-induced aggregation of α-synuclein in M83 neurons reveals remodeling of proteostasis mechanisms that might contribute to Parkinson’s disease pathogenesis	42
Protocadherin 19 regulates axon guidance in the developing Xenopus retinotectal pathway	39
Correction to: Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity	35
Correction to: Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease	35
A novel mouse model for investigating α-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy	33
mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons	33
Chronic corticosterone exposure causes anxiety- and depression-related behaviors with altered gut microbial and brain metabolomic profiles in adult male C57BL/6J mice	33
The parabrachial-to-amygdala pathway provides aversive information to induce avoidance behavior in mice	31
Inhibition of cortical synaptic transmission, behavioral nociceptive, and anxiodepressive-like responses by arecoline in adult mice	31
New neurons in old brains: implications of age in the analysis of neurogenesis in post-mortem tissue	30
Impact of volume and expression time in an AAV-delivered channelrhodopsin	28
Loss of Drosophila Coq8 results in impaired survival, locomotor deficits and photoreceptor degeneration	28
AKAP6 controls NFATc4 activity for BDNF-mediated neuroprotection	28
Optimization of protocols for pre-embedding immunogold electron microscopy of neurons in cell cultures and brains	27
Histamine H3 receptor inverse agonists/antagonists influence intra-regional cortical activity and inter-regional synchronization during resting state: an exploratory cortex-wide imaging study in mice	27
Correction: The deficiency of Maged1 attenuates Parkinson’s disease progression in mice	26
Arginine vasopressin in the medial amygdala causes greater post-stress recruitment of hypothalamic vasopressin neurons	26
Dynamic changes in the hippocampal neuronal circuits activity following acute stress revealed by miniature fluorescence microscopy imaging	26
The brain cytokine orchestra in multiple sclerosis: from neuroinflammation to synaptopathology	25
A simple and reliable method for claustrum localization across age in mice	24
Olfactory receptor 78 is expressed in hypothalamic vasopressin/oxytocin neurons, parenchymal microglia and choroidal macrophages in mice	23

Aversive emotion rapidly activates orexin neurons and increases heart rate in freely moving mice	23
Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation	23
Sonic hedgehog signalling pathway in CNS tumours: its role and therapeutic implications	22
Kdm3b haploinsufficiency impairs the consolidation of cerebellum-dependent motor memory in mice	22
Novelty-induced memory consolidation is accompanied by increased Agap3 transcription: a cross-species study	22
Riluzole partially restores RNA polymerase III complex assembly in cells expressing the leukodystrophy-causative variant POLR3B R103H	21
Chemogenetic activation of histamine neurons promotes retrieval of apparently lost memories	21
Post-conditioning sleep deprivation facilitates delay and trace fear memory extinction	20
Chronic pain enhances excitability of corticotropin-releasing factor-expressing neurons in the oval part of the bed nucleus of the stria terminalis	20
Involvement of posterior hypothalamic CaMKII-positive neurons in ADHD-like behaviors in mice	20
Cannabinoid receptors distribution in mouse cortical plasma membrane compartments	20
VMAT2 availability in Parkinson’s disease with probable REM sleep behaviour disorder	19
Electroacupuncture improves repeated social defeat stress-elicited social avoidance and anxiety-like behaviors by reducing Lipocalin-2 in the hippocampus	19
Nanoscale organization of Nicastrin, the substrate receptor of the γ-secretase complex, as independent molecular domains	19
Selective enhancement of fear extinction by inhibiting neuronal adenylyl cyclase 1 (AC1) in aged mice	19
A new paradigm of learned cooperation reveals extensive social coordination and specific cortical activation in mice	18
Reductions in midbrain GABAergic and dopamine neuron markers are linked in schizophrenia	18
Reduced activity of parvalbumin-positive interneurons in the posterior parietal cortex causes visually dominant multisensory decisions in freely navigating mice	18
MeCP2 deficiency impairs motor cortical circuit flexibility associated with motor learning	18
Atg7 deficiency in microglia drives an altered transcriptomic profile associated with an impaired neuroinflammatory response	18
Subacute and chronic proteomic and phosphoproteomic analyses of a mouse model of traumatic brain injury at two timepoints and comparison with chronic traumatic encephalopathy in human samples	18
Impaired wakefulness and rapid eye movement sleep in dopamine-deficient mice	18
The terpenes alpha-bisabolol and camphene modulate pruritus via an action on Cav3.2 T-type calcium channels	18
Olfactory marker protein contains a leucine-rich domain in the Ω-loop important for nuclear export	18
Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease	17
Intravitreal injection of the Galectin-3 inhibitor TD139 provides neuroprotection in a rat model of ocular hypertensive glaucoma	17
Increased social interaction in Shank2-deficient mice following acute social isolation	16
The gut microbiota and metabolite profiles are altered in patients with spinal cord injury	16
Moxibustion ameliorates chronic inflammatory visceral pain via spinal circRNA-miRNA-mRNA networks: a central mechanism study	16
Pathophysiology of ion channels in amyotrophic lateral sclerosis	16
Correction to: Networked neural spheroid by neuro-bundle mimicking nervous system created by topology effect	16
Neurexin-3 in the paraventricular nucleus of the hypothalamus regulates body weight and glucose homeostasis independently of food intake	16
Region-specific activation in the accumbens nucleus by itch with modified scratch efficacy in mice – a model-free multivariate analysis	15
Spermidine treatment: induction of autophagy but also apoptosis?	15
A natural marmoset model of genetic generalized epilepsy	15
High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression	14
Changes in oligodendroglial subpopulations in Parkinson’s disease	14
Novelty triggers time-dependent theta oscillatory dynamics in cortical-hippocampal-midbrain circuitry	14
Chronic skin ultraviolet irradiation induces transcriptomic changes associated with microglial dysfunction in the hippocampus	13
Reversibility of motor dysfunction in the rat model of NGLY1 deficiency	13
mTORC1 function in hippocampal parvalbumin interneurons: regulation of firing and long-term potentiation of intrinsic excitability but not long-term contextual fear memory and context discrimination	13
Selectively increasing GHS-R1a expression in dCA1 excitatory/inhibitory neurons have opposite effects on memory encoding	13
Toll-like receptors and their role in neuropathic pain and migraine	13
Disruption of the astrocyte–neuron interaction is responsible for the impairments in learning and memory in 5XFAD mice: an Alzheimer’s disease animal model	12
Comparative metabolic profiling of posterior parietal cortex, amygdala, and hippocampus in conditioned fear memory	12
NEK7 induces lactylation in Alzheimer’s disease to promote pyroptosis in BV-2 cells	12
Elucidation of the mechanisms underlying tumor aggravation by the activation of stress-related neurons in the paraventricular nucleus of the hypothalamus	12
Sonication dissociates the synaptic cleft and allows purification of postsynaptic densities with associated postsynaptic membrane	12
Genetic deletion of nitric oxide synthase 2 ameliorates Parkinson’s disease pathology and neuroinflammation in a transgenic mouse model of synucleinopathy	12
Spinal microglia contribute to sustained inflammatory pain via amplifying neuronal activity	12

TREM2 improves microglia function and synaptic development in autism spectrum disorders by regulating P38 MAPK signaling pathway	12
Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD	12
Age-related increase in caveolin-1 expression facilitates cell-to-cell transmission of α-synuclein in neurons	12
Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state	11
Limitations of the human iPSC-derived neuron model for early-onset Alzheimer’s disease	11
Analysis of neurexin-neuroligin complexes supports an isoform-specific role for beta-neurexin-1 dysfunction in a mouse model of autism	11
Activation of angiotensin-converting enzyme 2 produces an antidepressant-like effect via MAS receptors in mice	11
Neuropathological and behavioral features of an APP/PS1/MAPT (6xTg) transgenic model of Alzheimer’s disease	11
Splice-variant specific effects of a CACNA1H mutation associated with writer’s cramp	11
Correction: Requirement for hippocampal CA3 NMDA receptors in artificial association of memory events stored in CA3 cell ensembles	11
Integrated genomic and DNA methylation analysis of patients with advanced non-small cell lung cancer with brain metastases	11
The adaptor protein PICK1 targets the sorting receptor SorLA	11
Y-27632, a ROCK inhibitor, improved laser-induced shock wave (LISW)-induced cochlear synaptopathy in mice	11
Brain-derived neurotrophic factor produced long-term synaptic enhancement in the anterior cingulate cortex of adult mice	10
Hypoxia with inflammation and reperfusion alters membrane resistance by dynamically regulating voltage-gated potassium channels in hippocampal CA1 neurons	10
Crucial role of TFAP2B in the nervous system for regulating NREM sleep	10
Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism	10
Behavioral phenotype, intestinal microbiome, and brain neuronal activity of male serotonin transporter knockout mice	10
Nek6 regulates autophagy through the mTOR signaling pathway to alleviate cerebral ischemia–reperfusion injury	10
Astrocytic activation increases blood flow in the adult olfactory bulb	10
Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons	10
Age-related attenuation of cortical synaptic tagging in the ACC is rescued by BDNF or a TrkB receptor agonist in both sex of mice	10
A new AAV tool for highly preferentially targeting hippocampal CA2	10
Correction: Extinction of contextual fear memory is facilitated in TRPM2 knockout mice	10
Synergistic actions of corticosterone and BDNF on rat hippocampal LTP	9
Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation	9
Peripheral-central network analysis of cancer cachexia status accompanied by the polarization of hypothalamic microglia with low expression of inhibitory immune checkpoint receptors	9
Outer layer of Vb neurons in medial entorhinal cortex project to hippocampal dentate gyrus in mice	9
Deleting IP6K1 stabilizes neuronal sodium–potassium pumps and suppresses excitability	9
Inhibitory insula-ACC projections modulate affective but not sensory aspects of neuropathic pain	9
Hypothalamic protein profiling from mice subjected to social defeat stress	9
PV-IRES-Cre mouse line targets excitatory granule neurons in the cerebellum	9
Inhibition of autophagy by CRMP2-derived peptide ST2-104 (R9-CBD3) via a CaMKKβ/AMPK/mTOR pathway contributes to ischemic postconditioning-induced neuroprotection against cerebral ischemia-reperfusion	9
Correction to: Developmental up-regulation of NMDA receptors in the prefrontal cortex and hippocampus of mGlu5 receptor knock-out mice	9
Regulation of dendritic spine length in corticopontine layer V pyramidal neurons by autism risk gene β3 integrin	9
Acute social defeat stress activated neurons project to the claustrum and basolateral amygdala	9
Experience-dependent changes in affective valence of taste in male mice	9
The absence of Neuroligin-1 shapes wake/sleep architecture, rhythmic and arrhythmic activities of the electrocorticogram in female mice	9
Neurexin-1-dependent circuit activity is required for the maintenance of photoreceptor subtype identity in Drosophila	9
The phosphorylation status of eukaryotic elongation factor-2 indicates neural activity in the brain	9
Quercetin carbon quantum dots: dual-target therapy for intracerebral hemorrhage in mice	9
Locus specific reduction of L1 expression in the cortices of individuals with amyotrophic lateral sclerosis	8
Astrocyte-derived dominance winning reverses chronic stress-induced depressive behaviors	8
Disrupting the α7nAChR–NR2A protein complex exerts antidepressant-like effects	8
Changes in the pH value of the human brain in Alzheimer’s disease pathology correlated with CD68-positive microglia: a community-based autopsy study in Beijing, China	8
Function of KCNQ2 channels at nodes of Ranvier of lumbar spinal ventral nerves of rats	8
Circadian cilia transcriptome in mouse brain across physiological and pathological states	8
Decreased expression of the clock gene Bmal1 is involved in the pathogenesis of temporal lobe epilepsy	8
Targeted NMDA receptor knockdown in recall‐activated neuronal ensembles impairs remote fear extinction	8
Minhee Analysis Package: an integrated software package for detection and management of spontaneous synaptic events	8
Proteasome inhibition suppresses the induction of lipocalin-2 upon systemic lipopolysaccharide challenge in mice	8
Sleep-driven prefrontal cortex coordinates temporal action and multimodal integration	8
Cavβ surface charged residues contribute to the regulation of neuronal calcium channels	8
Temporal pain processing in the primary somatosensory cortex and anterior cingulate cortex	8
Mechanisms of glutamate receptors hypofunction dependent synaptic transmission impairment in the hippocampus of schizophrenia susceptibility gene Opcml-deficient mouse model	7
Neural stem cell-specific deletion of Atg7 alleviates hippocampal dysfunction and neuronal alterations induced by chronic restraint stress	7
Rapid generation of conditional knockout mice using the CRISPR-Cas9 system and electroporation for neuroscience research	7
Long non-coding RNA lncC11orf54-1 modulates neuroinflammatory responses by activating NF-κB signaling during meningitic Escherichia coli infection	7
Astrocyte metabolism of the medium-chain fatty acids octanoic acid and decanoic acid promotes GABA synthesis in neurons via elevated glutamine supply	7
Modulating and monitoring the functionality of corticostriatal circuits using an electrostimulable microfluidic device	7
Knockdown of myorg leads to brain calcification in zebrafish	7
Hes5+ astrocytes potentiate primary afferent Aδ and C fiber-mediated excitatory synaptic transmission to spinal lamina I neurons	7
Decreased in vivo glutamate/GABA ratio correlates with the social behavior deficit in a mouse model of autism spectrum disorder	7
Prior episode of colitis impairs contextual fear memory	7
The cyclin G-associated kinase (GAK) inhibitor SGC-GAK-1 inhibits neurite outgrowth and synapse formation	7
Development of a rabies virus-based retrograde tracer with high trans-monosynaptic efficiency by reshuffling glycoprotein	6
Blood–brain barrier: emerging trends on transport models and new-age strategies for therapeutics intervention against neurological disorders	6
Spatiotemporal expression patterns of genes coding for plasmalemmal chloride transporters and channels in neurological diseases	6
Distribution of five clinically important neuroglial proteins in the human brain	6
Retina-attached slice recording reveals light-triggered tonic GABA signaling in suprachiasmatic nucleus	6
Similarities of developmental gene expression changes in the brain between human and experimental animals: rhesus monkey, mouse, Zebrafish, and Drosophila	6
Brain region networks for the assimilation of new associative memory into a schema	6
De novo SCN8A and inherited rare CACNA1H variants associated with severe developmental and epileptic encephalopathy	6
14-3-3γ haploinsufficiency leads to altered dopamine pathway and Parkinson’s disease-like motor incoordination in mice	6
Homocysteine enhances the excitability of cultured hippocampal neurons without altering the gene expression of voltage-gated ion channels	6
Correction: The properties of TREM1 and its emerging role in pain-related diseases	6
Anxiolytic effect of GABAergic neurons in the anterior cingulate cortex in a rat model of chronic inflammatory pain	6
Postmortem gene expression profiles in the habenulae of suicides: implication of endothelial dysfunction in the neurovascular system	6
Hif1α-dependent hypoxia signaling contributes to the survival of deep-layer neurons and cortex formation in a mouse model	6
Distinct neural responses of ventromedial prefrontal cortex-projecting nucleus reuniens neurons during aversive memory extinction	6

BCAT1 controls embryonic neural stem cells proliferation and differentiation in the upper layer neurons	6
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo	6
Visualization of the existence of growth hormone secretagogue receptor in the rat nucleus accumbens	5
Maturation of nucleus accumbens synaptic transmission signals a critical period for the rescue of social deficits in a mouse model of autism spectrum disorder	5
A large-scale polygenic risk score analysis identified candidate proteins associated with anxiety, depression and neuroticism	5
Running-induced neurogenesis reduces CA1 perineuronal net density without substantial temporal delay	5
Dihydroartemisinin attenuates hypoxic-ischemic brain damage in neonatal rats by inhibiting oxidative stress	5
Divergent disruptive effects of soluble recombinant tau assemblies on synaptic plasticity in vivo	5
Modifiable risk factors that mediate the effect of educational attainment on the risk of stroke: a network Mendelian randomization study	5
Virally mediated expression of a biologically active peptide to restrain the nuclear functions of ERK1/2 attenuates learning extinction but not acquisition	5
Ameliorative effects of Fingolimod (FTY720) on microglial activation and psychosis-related behavior in short term cuprizone exposed mice	5
Olfactory marker protein is unlikely to be cleaved by calpain 5	5
DYRK1A modulates fear memory formation via epigenetic modification	5
Characterization of exosome-mediated propagation of systemic inflammatory responses into the central nervous system	5
Ultrastructural characterization of hippocampal inhibitory synapses under resting and stimulated conditions	5
Enhanced synchronization between prelimbic and infralimbic cortices during fear extinction learning	5
Genome-wide translation control analysis of developing human neurons	5
Ackr3-Venus knock-in mouse lights up brain vasculature	5
Epigenetic signature of N-terminal acetyltransferases: a probable mediator of immune and neuropathogenesis in HIV infection	5
Analgesia by intrathecal delta-9-tetrahydrocannabinol is dependent on Cav3.2 calcium channels	5
Globus pallidus is not independent from striatal direct pathway neurons: an up-to-date review	5
Development of Cre-dependent retrograde trans-multisynaptic tracer based on pseudorabies virus bartha strain	5
Felodipine attenuates neuroinflammatory responses and tau hyperphosphorylation through JNK/P38 signaling in tau-overexpressing AD mice	5
Tyrosine phosphatase STEP61 in human dementia and in animal models with amyloid and tau pathology	5
Association of CaMK2A and MeCP2 signaling pathways with cognitive ability in adolescents	5
Cortical pain induced by optogenetic cortical spreading depression: from whole brain activity mapping	5
Cerebellar damage with inflammation upregulates oxytocin receptor expression in Bergmann Glia	5
Correction to: Oxytocin ameliorates impaired social behavior in a mouse model of 3q29 deletion syndrome	5
Chemogenetic silencing of the subiculum blocks acute chronic temporal lobe epilepsy	4
RNA-seq co-expression network analysis reveals anxiolytic behavior of mice with Efnb2 knockout in parvalbumin+ neurons	4
Novel epigenetic clock for fetal brain development predicts prenatal age for cellular stem cell models and derived neurons	4
Cell-line dependency in cerebral organoid induction: cautionary observations in Alzheimer’s disease patient-derived induced pluripotent stem cells	4
Roles of mediodorsal thalamus in observational fear-related neural activity in mouse anterior cingulate cortex	4
Assessing the effect of interaction between C-reactive protein and gut microbiome on the risks of anxiety and depression	4
The deficiency of Maged1 attenuates Parkinson's disease progression in mice	4
Transcriptome atlases of rat brain regions and their adaptation to diabetes resolution following gastrectomy in the Goto-Kakizaki rat	4
C1ql1-Bai3 signaling is necessary for climbing fiber synapse formation in mature Purkinje cells in coordination with neuronal activity	4
Improving working memory by electrical stimulation and cross-frequency coupling	4
Burst firing is required for induction of Hebbian LTP at lateral perforant path to hippocampal granule cell synapses	4
In vitro modulation of mTOR and mGlur5 influence α-synuclein accumulation	4
Transient inhibition of microsomal prostaglandin E synthase-1 after status epilepticus blunts brain inflammation and is neuroprotective	4
Antihyperalgesic effect of joint mobilization requires Cav3.2 calcium channels	4
Comprehensive behavioral analyses of mice with a glycine receptor alpha 4 deficiency	4
Antiallodynic effects of KDS2010, a novel MAO-B inhibitor, via ROS-GABA inhibitory transmission in a paclitaxel-induced tactile hypersensitivity model	4
Functional characterization of a novel de novo CACNA1C pathogenic variant in a patient with neurodevelopmental disorder	4
A structural analysis of the splice-specific functional impact of the pathogenic familial hemiplegic migraine type 1 S218L mutation on Cav2.1 P/Q-type channel gating	4
Surgery impairs glymphatic activity and cognitive function in aged mice	4
Properties of Nav1.8ChR2-positive and Nav1.8ChR2-negative afferent mechanoreceptors in the hindpaw glabrous skin of mice	4
Optogenetic activation of dopamine D1 receptors in island cells of medial entorhinal cortex inhibits temporal association learning	4
Expression profile of synaptic vesicle glycoprotein 2A, B, and C paralogues in temporal neocortex tissue from patients with temporal lobe epilepsy (TLE)	4
Transcriptomic profiling of high- and low-spiking regions reveals novel epileptogenic mechanisms in focal cortical dysplasia type II patients	4
Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition	4
Involvement of muscarinic receptors in psychomotor hyperactivity in dopamine-deficient mice	4
Microtubule-associated protein 1 A and tubby act independently in regulating the localization of stereocilin to the tips of inner ear hair cell stereocilia	4
Paraventricular hypothalamic vasopressin neurons induce self-grooming in mice	4
Deoxyhypusine synthase deficiency syndrome zebrafish model: aberrant morphology, epileptiform activity, and reduced arborization of inhibitory interneurons	4
Development of a novel peptide to prevent entry of SARS-CoV-2 into lung and olfactory bulb cells of hACE2 expressing mice	4
Exploration of new space elicits phosphorylation of GluA1(Ser831) and S6K and expression of Arc in the hippocampus in vivo as in long-term potentiation	4
CaVβ-subunit dependence of forward and reverse trafficking of CaV1.2 calcium channels	4
Somatostatin contributes to long-term potentiation at excitatory synapses onto hippocampal somatostatinergic interneurons	4
Transcriptomic changes in oligodendrocytes and precursor cells associate with clinical outcomes of Parkinson’s disease	4
Extinction of contextual fear memory is facilitated in TRPM2 knockout mice	4