OOIR: Observatory of International Research

Papers

(The TQCC of Molecular Brain is 9. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Knockout of AMPA receptor binding protein Neuron-specific gene 2 (NSG2) enhances associative learning and cognitive flexibility	79
FMRP binds Per1 mRNA and downregulates its protein expression in mice	59
Spatiotemporal Pavlovian head-fixed reversal learning task for mice	54
Broad proteomics analysis of seeding-induced aggregation of α-synuclein in M83 neurons reveals remodeling of proteostasis mechanisms that might contribute to Parkinson’s disease pathogenesis	52
Correction to: Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease	44
Correction to: Roles of Rufy3 in experimental subarachnoid hemorrhage-induced early brain injury via accelerating neuronal axon repair and synaptic plasticity	43
Recent developments in peptide vaccines against Glioblastoma, a review and update	43
Protocadherin 19 regulates axon guidance in the developing Xenopus retinotectal pathway	39
mTORC1-mediated acquisition of reward-related representations by hippocampal somatostatin interneurons	35
A novel mouse model for investigating α-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy	35
New neurons in old brains: implications of age in the analysis of neurogenesis in post-mortem tissue	35
Diurnal variation in declarative memory and the involvement of SCOP in cognitive functions in nonhuman primates	33
Chronic corticosterone exposure causes anxiety- and depression-related behaviors with altered gut microbial and brain metabolomic profiles in adult male C57BL/6J mice	33
Inhibition of cortical synaptic transmission, behavioral nociceptive, and anxiodepressive-like responses by arecoline in adult mice	32
Arginine vasopressin in the medial amygdala causes greater post-stress recruitment of hypothalamic vasopressin neurons	30
AKAP6 controls NFATc4 activity for BDNF-mediated neuroprotection	30
Role of autophagy in neurotoxic protein’s clearance following post-ischemic stroke: where we are and what we know?	28
Correction: The deficiency of Maged1 attenuates Parkinson’s disease progression in mice	26
Impact of volume and expression time in an AAV-delivered channelrhodopsin	26
The brain cytokine orchestra in multiple sclerosis: from neuroinflammation to synaptopathology	26
Correction to: Synergistic actions of corticosterone and BDNF on rat hippocampal LTP	24
A simple and reliable method for claustrum localization across age in mice	24
Chronic oral administration of ibrutinib prevents long-term memory deficits and reduces AD pathology and neuroinflammatory responses in a mouse model of AD	24
Dynamic changes in the hippocampal neuronal circuits activity following acute stress revealed by miniature fluorescence microscopy imaging	24
Loss of Drosophila Coq8 results in impaired survival, locomotor deficits and photoreceptor degeneration	24

Histamine H3 receptor inverse agonists/antagonists influence intra-regional cortical activity and inter-regional synchronization during resting state: an exploratory cortex-wide imaging study in mice	23
Riluzole partially restores RNA polymerase III complex assembly in cells expressing the leukodystrophy-causative variant POLR3B R103H	22
Chemogenetic activation of histamine neurons promotes retrieval of apparently lost memories	22
Involvement of posterior hypothalamic CaMKII-positive neurons in ADHD-like behaviors in mice	22
Sonic hedgehog signalling pathway in CNS tumours: its role and therapeutic implications	22
Olfactory receptor 78 is expressed in hypothalamic vasopressin/oxytocin neurons, parenchymal microglia and choroidal macrophages in mice	21
Nanoscale organization of Nicastrin, the substrate receptor of the γ-secretase complex, as independent molecular domains	20
Novelty-induced memory consolidation is accompanied by increased Agap3 transcription: a cross-species study	20
Chronic pain enhances excitability of corticotropin-releasing factor-expressing neurons in the oval part of the bed nucleus of the stria terminalis	20
Post-conditioning sleep deprivation facilitates delay and trace fear memory extinction	20
Olfactory marker protein contains a leucine-rich domain in the Ω-loop important for nuclear export	19
Electroacupuncture improves repeated social defeat stress-elicited social avoidance and anxiety-like behaviors by reducing Lipocalin-2 in the hippocampus	19
Subacute and chronic proteomic and phosphoproteomic analyses of a mouse model of traumatic brain injury at two timepoints and comparison with chronic traumatic encephalopathy in human samples	18
The terpenes alpha-bisabolol and camphene modulate pruritus via an action on Cav3.2 T-type calcium channels	18
Reduced activity of parvalbumin-positive interneurons in the posterior parietal cortex causes visually dominant multisensory decisions in freely navigating mice	18
Selective enhancement of fear extinction by inhibiting neuronal adenylyl cyclase 1 (AC1) in aged mice	17
MeCP2 deficiency impairs motor cortical circuit flexibility associated with motor learning	17
VMAT2 availability in Parkinson’s disease with probable REM sleep behaviour disorder	17
Impaired wakefulness and rapid eye movement sleep in dopamine-deficient mice	16
A new paradigm of learned cooperation reveals extensive social coordination and specific cortical activation in mice	16
Synaptic potentiation of anterior cingulate cortex contributes to chronic pain of Parkinson’s disease	15
Moxibustion ameliorates chronic inflammatory visceral pain via spinal circRNA-miRNA-mRNA networks: a central mechanism study	14
Intravitreal injection of the Galectin-3 inhibitor TD139 provides neuroprotection in a rat model of ocular hypertensive glaucoma	14
Neurexin-3 in the paraventricular nucleus of the hypothalamus regulates body weight and glucose homeostasis independently of food intake	14
The gut microbiota and metabolite profiles are altered in patients with spinal cord injury	14
Increased social interaction in Shank2-deficient mice following acute social isolation	14
Pathophysiology of ion channels in amyotrophic lateral sclerosis	13
Region-specific activation in the accumbens nucleus by itch with modified scratch efficacy in mice – a model-free multivariate analysis	13
Spermidine treatment: induction of autophagy but also apoptosis?	13
A natural marmoset model of genetic generalized epilepsy	13
Novelty triggers time-dependent theta oscillatory dynamics in cortical-hippocampal-midbrain circuitry	13
Profiling tyrosine kinase inhibitors as AD therapeutics in a mouse model of AD	12
Sonication dissociates the synaptic cleft and allows purification of postsynaptic densities with associated postsynaptic membrane	12
Comparative metabolic profiling of posterior parietal cortex, amygdala, and hippocampus in conditioned fear memory	12
Changes in oligodendroglial subpopulations in Parkinson’s disease	12
Toll-like receptors and their role in neuropathic pain and migraine	12
Selectively increasing GHS-R1a expression in dCA1 excitatory/inhibitory neurons have opposite effects on memory encoding	12
mTORC1 function in hippocampal parvalbumin interneurons: regulation of firing and long-term potentiation of intrinsic excitability but not long-term contextual fear memory and context discrimination	11
Repeated naloxone-induced morphine withdrawal alters blood brain barrier and blood spinal cord barrier integrity in mice	11
Spinal microglia contribute to sustained inflammatory pain via amplifying neuronal activity	11
Genetic deletion of nitric oxide synthase 2 ameliorates Parkinson’s disease pathology and neuroinflammation in a transgenic mouse model of synucleinopathy	11
Chronic skin ultraviolet irradiation induces transcriptomic changes associated with microglial dysfunction in the hippocampus	11
Elucidation of the mechanisms underlying tumor aggravation by the activation of stress-related neurons in the paraventricular nucleus of the hypothalamus	11
TREM2 improves microglia function and synaptic development in autism spectrum disorders by regulating P38 MAPK signaling pathway	11
Integrated genomic and DNA methylation analysis of patients with advanced non-small cell lung cancer with brain metastases	11
Neuropathological and behavioral features of an APP/PS1/MAPT (6xTg) transgenic model of Alzheimer’s disease	11
High glucose and palmitic acid induces neuronal senescence by NRSF/REST elevation and the subsequent mTOR-related autophagy suppression	11
Activation of angiotensin-converting enzyme 2 produces an antidepressant-like effect via MAS receptors in mice	11
NEK7 induces lactylation in Alzheimer’s disease to promote pyroptosis in BV-2 cells	11
Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state	11

Brain-derived neurotrophic factor produced long-term synaptic enhancement in the anterior cingulate cortex of adult mice	10
The adaptor protein PICK1 targets the sorting receptor SorLA	10
Analysis of neurexin-neuroligin complexes supports an isoform-specific role for beta-neurexin-1 dysfunction in a mouse model of autism	10
Loss of mitochondrial enzyme GPT2 leads to reprogramming of synaptic glutamate metabolism	10
A new AAV tool for highly preferentially targeting hippocampal CA2	10
Astrocytic activation increases blood flow in the adult olfactory bulb	10
Correction: Requirement for hippocampal CA3 NMDA receptors in artificial association of memory events stored in CA3 cell ensembles	10
Nek6 regulates autophagy through the mTOR signaling pathway to alleviate cerebral ischemia–reperfusion injury	10
Limitations of the human iPSC-derived neuron model for early-onset Alzheimer’s disease	10
Splice-variant specific effects of a CACNA1H mutation associated with writer’s cramp	10
Crucial role of TFAP2B in the nervous system for regulating NREM sleep	10
Correction: Extinction of contextual fear memory is facilitated in TRPM2 knockout mice	10
Age-related attenuation of cortical synaptic tagging in the ACC is rescued by BDNF or a TrkB receptor agonist in both sex of mice	9
Hypothalamic protein profiling from mice subjected to social defeat stress	9
Peripheral-central network analysis of cancer cachexia status accompanied by the polarization of hypothalamic microglia with low expression of inhibitory immune checkpoint receptors	9
Synergistic actions of corticosterone and BDNF on rat hippocampal LTP	9
Generation of a new Slc20a2 knockout mouse line as in vivo model for primary brain calcification	9
Experience-dependent changes in affective valence of taste in male mice	9
The absence of Neuroligin-1 shapes wake/sleep architecture, rhythmic and arrhythmic activities of the electrocorticogram in female mice	9
PV-IRES-Cre mouse line targets excitatory granule neurons in the cerebellum	9
Behavioral phenotype, intestinal microbiome, and brain neuronal activity of male serotonin transporter knockout mice	9
Involvement of Cdk5 activating subunit p35 in synaptic plasticity in excitatory and inhibitory neurons	9
Neurexin-1-dependent circuit activity is required for the maintenance of photoreceptor subtype identity in Drosophila	9
Hypoxia with inflammation and reperfusion alters membrane resistance by dynamically regulating voltage-gated potassium channels in hippocampal CA1 neurons	9
Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation	9