OOIR: Observatory of International Research

Papers

(The H4-Index of Future Medicinal Chemistry is 22. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-06-01 to 2025-06-01.)

Article	Citations
In vivo evaluation of novel synthetic pyrazolones as CDK9 inhibitors with enhanced pharmacokinetic properties	57
Sulfonamide-salicylaldehyde Imines Active Against methicillin- and trimethoprim/sulfonamide-resistant Staphylococci	52
Design of SARS-CoV-2 Mpro, PLpro Dual-Target Inhibitors Based on Deep Reinforcement Learning and Virtual Screening	47
Design and synthesis of new nicotinamides as immunomodulatory VEGFR-2 inhibitors and apoptosis inducers	45
Combining EGFR Inhibitors With SHP2 Or LSD1 Inhibitors to Overcome Multidrug Resistance in Cancer	45
Biological and computational evaluation of novel benzofuranyl derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors	39
Identification of Sulfonamide-Based Butyrylcholinesterase Inhibitors Using Machine Learning	38
Citrate Transporter Inhibitors: Possible New Anticancer Agents	38
Novel Set of Highly Substituted Bis-Pyridines: Synthesis, Molecular Docking and Drug-Resistant Antibacterial Profile	37
Therapeutic N -Heterocyclic Carbenes: An Interview With Alejandro Bugarin	37
The Connection Between PARP14 and SARS-CoV-2	35
Super-Conserved Receptors Expressed in the Brain: Biology and Medicinal Chemistry Efforts	31
Targeting Tuberculosis – An Interview With Robert Abramovitch	28
A Review of Current and Promising Nontuberculous Mycobacteria Antibiotics	28
Selection of SARS-CoV-2 Main Protease Inhibitor Using Structure-Based Virtual Screening	28
Combining Structure-Based and 3D QSAR Pharmacophore Models to Discover Diverse Ligands Against EGFR in Oral Cancer	27
Investigations of New N ¹ -Substituted Pyrazoles as Anti-Inflammatory and Analgesic Agents having COX Inhibitory Act	27
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity	27
5,7,3′,4′-Tetramethoxyflavone Ameliorates Cholesterol Dysregulation by Mediating SIRT1/FOXO3a/ABCA1 Signaling in Osteoarthritis Chondrocytes	26
Synthesis of Hydrazinyl–Thiazole Ester Derivatives, in Vitro Trypanocidal and Leishmanicidal Activities	24
Rh(III) and Ru(II) Complexes With Phosphanyl–Alkylamines: Inhibition of DNA Synthesis Induced By Anticancer Rh Complex	22
Synergistic effect of new pyrimidine derivative with oxacilin against methicillin-resistant Staphylococcus aureus	22