OOIR: Observatory of International Research

Papers

(The H4-Index of Future Medicinal Chemistry is 23. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-09-01 to 2025-09-01.)

Article	Citations
Sulfonamide-salicylaldehyde Imines Active Against methicillin- and trimethoprim/sulfonamide-resistant Staphylococci	60
Super-Conserved Receptors Expressed in the Brain: Biology and Medicinal Chemistry Efforts	57
Design of SARS-CoV-2 Mpro, PLpro Dual-Target Inhibitors Based on Deep Reinforcement Learning and Virtual Screening	57
Combining EGFR Inhibitors With SHP2 Or LSD1 Inhibitors to Overcome Multidrug Resistance in Cancer	53
Combining Structure-Based and 3D QSAR Pharmacophore Models to Discover Diverse Ligands Against EGFR in Oral Cancer	52
Biological and computational evaluation of novel benzofuranyl derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors	51
Citrate Transporter Inhibitors: Possible New Anticancer Agents	44
Identification of Sulfonamide-Based Butyrylcholinesterase Inhibitors Using Machine Learning	44
The Connection Between PARP14 and SARS-CoV-2	39
Therapeutic N -Heterocyclic Carbenes: An Interview With Alejandro Bugarin	39
Targeting Tuberculosis – An Interview With Robert Abramovitch	38
Selection of SARS-CoV-2 Main Protease Inhibitor Using Structure-Based Virtual Screening	36
Investigations of New N ¹ -Substituted Pyrazoles as Anti-Inflammatory and Analgesic Agents having COX Inhibitory Act	31
Development of 5-hydroxybenzothiophene derivatives as multi-kinase inhibitors with potential anti-cancer activity	31
Novel Set of Highly Substituted Bis-Pyridines: Synthesis, Molecular Docking and Drug-Resistant Antibacterial Profile	30
In vivo evaluation of novel synthetic pyrazolones as CDK9 inhibitors with enhanced pharmacokinetic properties	28
The role of descriptors extracted from ligand-target interaction to improve conventional QSAR model performance in the realm of angiogenesis receptor modulation to fight cancer	27
Design and synthesis of new nicotinamides as immunomodulatory VEGFR-2 inhibitors and apoptosis inducers	26
Barbiturate–sulfonate hybrids as potent cholinesterase inhibitors: design, synthesis and molecular modeling studies	23
Synergistic effect of new pyrimidine derivative with oxacilin against methicillin-resistant Staphylococcus aureus	23
HDAC8 As an Emerging Target in Drug Discovery With Special Emphasis on Medicinal Chemistry	23
Rh(III) and Ru(II) Complexes With Phosphanyl–Alkylamines: Inhibition of DNA Synthesis Induced By Anticancer Rh Complex	23
Propargylamine: an Important Moiety in Drug Discovery	23