OOIR: Observatory of International Research

Papers

(The median citation count of Epigenetics & Chromatin is 4. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation	58
DNA methylation reshapes the expression of adipokines and adipose factors in white adipose tissues	53
The role of genetic diversity, epigenetic regulation, and sex-based differences in HIV cure research: a comprehensive review	41
An optimized approach for multiplexing single-nuclear ATAC-seq using oligonucleotide-conjugated antibodies	40
Epigenetic regulation of MED12: a key contributor to the leukemic chromatin landscape and transcriptional dysregulation	38
Proteins driving liquid-liquid phase separation and histone modifications cooperatively associate with chromatin looping and transcriptional regulation	36
Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation	35
Co-effects of m6A and chromatin accessibility dynamics in the regulation of cardiomyocyte differentiation	34
Cooperation between architectural C2H2 proteins in CP190 recruitment to Drosophila regulatory elements	33
Features of DNA methylome in Capsicum spp.	33
Detecting Protein-DNA binding in single molecules using antibody guided methylation	31
From compartments to loops: understanding the unique chromatin organization in neuronal cells	30
Local chromatin context informs transcriptional outcomes for the histone demethylase KDM5	26
Chromatin structure and 3D architecture define the differential functions of PU.1 regulatory elements in blood cell lineages	26
Evolutionary adaptation of the Polycomb repressive complex 2	24
Mouse Chd4-NURD is required for neonatal spermatogonia survival and normal gonad development	23
Partial erosion on under-methylated regions and chromatin reprogramming contribute to oncogene activation in IDH mutant gliomas	22
Gain of function p53 mutant R273H confers distinct methylation profiles and consequent YAP/TAZ signaling mediated activation of partial or full EMT states to colon tumours	22
Protamine expression in somatic cells condenses chromatin and disrupts transcription without altering DNA methylation	22
Mechanistic basis for the opposing effects of H2A and H2B ubiquitination on nucleosome stability and dynamics	21
Who’s afraid of the X? Incorporating the X and Y chromosomes into the analysis of DNA methylation array data	21
Intrafamily heterooligomerization as an emerging mechanism of methyltransferase regulation	19
Acetylation modification of AIM2 by KAT2B suppresses the AKT/Wnt/β-catenin signaling pathway activation and inhibits breast cancer progression	19
Development of super-specific epigenome editing by targeted allele-specific DNA methylation	19
Chromatin balances cell redox and energy homeostasis	18

Phthalates impact on the epigenetic factors contributed specifically by the father at fertilization	18
Heterosis of growth trait regulated by DNA methylation and miRNA in allotriploid fish	17
Analysis of long-range chromatin contacts, compartments and looping between mouse embryonic stem cells, lens epithelium and lens fibers	17
CpG DNA methylation changes during epididymal sperm maturation in bulls	17
Roles of post-translational modifications of UHRF1 in cancer	17
Acquired sperm hypomethylation by gestational arsenic exposure is re-established in both the paternal and maternal genomes of post-epigenetic reprogramming embryos	17
Native and tagged CENP-A histones are functionally inequivalent	16
Manipulating chromatin architecture in C. elegans	16
Integrated study of DNA methylation and transcriptome: a new perspective for exploring the pathogenesis of Sjögren's syndrome	15
ING5: multifaceted roles beyond tumor suppression in cellular physiology and disease	15
Multi-omic integration of single-cell data uncovers methylation profiles of super-enhancers in skeletal muscle stem cells	15
H3K27me3 and the PRC1-H2AK119ub pathway cooperatively maintain heterochromatin and transcriptional silencing after the loss of H3K9 methylation	14
Impact of chromatin on HIV-1 latency: a multi-dimensional perspective	14
TP63–TRIM29 axis regulates enhancer methylation and chromosomal instability in prostate cancer	14
The WAC-downWAC domain in the yeast ISW2 nucleosome remodeling complex forms a structural module essential for ISW2 function but not cell viability	14
PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome	14
Mitochondrial supplementation of Sus scrofa metaphase II oocytes alters DNA methylation and gene expression profiles of blastocysts	14
Knockout tales: the versatile roles of histone H3.3 in development and disease	13
Epigenetic control of dental stem cells: progress and prospects in multidirectional differentiation	13
Cohesin regulation of genome organization in mature granule neurons in the mouse cerebellum	13
Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation	13
Structural and functional specificity of H3K36 methylation	13
Mechanism of non-coding RNA regulation of DNMT3A	13
Multi-omics analyses of MEN1 missense mutations identify disruption of menin–MLL and menin–JunD interactions as critical requirements for molecular pathogenicity	12
Making sense of the linear genome, gene function and TADs	12
Investigation of reversible histone acetylation and dynamics in gene expression regulation using 3D liver spheroid model	12
Identification of genetic and non-genetic modifiers of genomic imprinting through screening of imprinted DMR methylation in humans	12
TET-mediated DNA hydroxymethylation is negatively influenced by the PARP-dependent PARylation	12
Reinforcement of repressive marks in the chicken primordial germ cell epigenetic signature: divergence from basal state resetting in mammals	12
Effects of paternal exposure to cigarette smoke on sperm DNA methylation and long-term metabolic syndrome in offspring	12
ZAD mediates chromatin binding and insulator activity of Drosophila Pita and can be replaced with the human ZFP276 ZAD-like domain	11
Optimizing genetic ancestry adjustment in DNA methylation studies: a comparative analysis of approaches	11
Prenatal nicotine exposure leads to epigenetic alterations in peripheral nervous system signaling genes in the testis of the rat	11
Histone H3.3 K27M chromatin functions implicate a network of neurodevelopmental factors including ASCL1 and NEUROD1 in DIPG	11
Premature ovarian insufficiency is associated with global alterations in the regulatory landscape and gene expression in balanced X-autosome translocations	11
Functions of HP1 proteins in transcriptional regulation	10
Genome-wide DNA methylation patterns in Daphnia magna are not significantly associated with age	10
Promoter hypermethylation of neural-related genes is compatible with stemness in solid cancers	10
Drosophila architectural proteins M1BP and Opbp cooperatively form the active promoter of a ribosomal protein gene	10
Pioneer transcription factors are associated with the modulation of DNA methylation patterns across cancers	10
The linker histone chaperone Prothymosin α (PTMA) is essential for efficient DNA damage repair and the recruitment of PARP1	10
Var∣Decrypt: a novel and user-friendly tool to explore and prioritize variants in whole-exome sequencing data	10
TET1 functions as a tumor suppressor in lung adenocarcinoma through epigenetic remodeling and immune modulation	10
Dna methylation dynamics associated with visual system remodeling during flatfish metamorphosis	9
H3K4me3 regulates the transcription of RSPO3 in dermal papilla cells to influence hair follicle morphogenesis and development	9
PCGF6/MAX/KDM5D facilitates MAZ/CDK4 axis expression and pRCC progression by hypomethylation of the DNA promoter	9
Histone modification analysis reveals common regulators of gene expression in liver and blood stage merozoites of Plasmodium parasites	9
Cohesin stabilization at promoters and enhancers by common transcription factors and chromatin regulators	9
The transgenic IG-DMR sequence of the mouse Dlk1-Dio3 domain acquired imprinted DNA methylation during the post-fertilization period	8
Correction: Characterizing chromatin interactions of regulatory elements and nucleosome positions, using Hi‑C, Micro‑C, and promoter capture Micro‑C	8

Functional characterization of transcriptional enhancers in an Anopheles genetic locus controlling natural resistance to the malaria parasite, Plasmodium falciparum	8
Dissecting the Kaiso binding profile in clear renal cancer cells	8
Analyses of POL30 (PCNA) reveal positional effects in transient repression or bi-modal active/silent state at the sub-telomeres of S. cerevisiae	8
Folate deficiency reduced aberrant level of DOT1L-mediated histone H3K79 methylation causes disruptive SHH gene expression involved in neural tube defects	7
DNA methylation may affect beef tenderness through signal transduction in Bos indicus	7
Correction: Acetylation modification of AIM2 by KAT2B suppresses the AKT/Wnt/β-catenin signaling pathway activation and inhibits breast cancer progression	7
Multigenerational temperature effects on paternal epigenetic inheritance in European sea bass	7
The isoflavone genistein selectively stimulates major satellite repeat transcription in mouse heterochromatin	6
Deconvolution of the epigenetic age discloses distinct inter-personal variability in epigenetic aging patterns	6
Improved epigenetic age prediction models by combining sex chromosome and autosomal markers	6
A standardized nomenclature for mammalian histone genes	6
Imprinted DNA methylation of the H19 ICR is established and maintained in vivo in the absence of Kaiso	6
Expanding the list of sequence-agnostic enzymes for chromatin conformation capture assays with S1 nuclease	6
Chromatin alterations during the epididymal maturation of mouse sperm refine the paternally inherited epigenome	6
Integrative analysis of gene expression and chromatin dynamics multi-omics data in mouse models of bleomycin-induced lung fibrosis	5
The mismatch-repair proteins MSH2 and MSH6 interact with the imprinting control regions through the ZFP57-KAP1 complex	5
Long-term exposure to diesel exhaust particles induces concordant changes in DNA methylation and transcriptome in human adenocarcinoma alveolar basal epithelial cells	5
The regional sequestration of heterochromatin structural proteins is critical to form and maintain silent chromatin	5
Bromodomain proteins IBD1 and IBD2 link histone acetylation to SWR1- and INO80-mediated H2A.Z regulation in Tetrahymena	5
Chromatin accessibility and cell cycle progression are controlled by the HDAC-associated Sin3B protein in murine hematopoietic stem cells	5
Methylation patterns at the adjacent CpG sites within enhancers are a part of cell identity	5
5-Hydroxymethylcytosine: a key epigenetic mark in cancer and chemotherapy response	4
Multiple distinct domains of human XIST are required to coordinate gene silencing and subsequent heterochromatin formation	4
Transcriptional regulation mechanism of PARP1 and its application in disease treatment	4
3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) risk	4
Disruption of histone acetylation homeostasis reveals multilayered chromatin regulation for transcriptional resiliency	4
Characterizing chromatin interactions of regulatory elements and nucleosome positions, using Hi-C, Micro-C, and promoter capture Micro-C	4
H3K9 post-translational modifications regulate epiblast/primitive endoderm specification in rabbit blastocysts	4
Correction: Dissecting the Kaiso binding profle in clear renal cancer cells	4
Pan-cancer predictions of transcription factors mediating aberrant DNA methylation	4
FOSL1 is a key regulator of a super-enhancer driving TCOF1 expression in triple-negative breast cancer	4
DNA methylation correlates of chronological age in diverse human tissue types	4
The MMP-2 histone H3 N-terminal tail protease is selectively targeted to the transcription start sites of active genes	4
LSD1 induces H3 K9 demethylation to promote adipogenesis in thyroid-associated ophthalmopathy	4
Genome-wide demethylation and targeted remethylation during metamorphosis in the jewel wasp Nasonia vitripennis	4
Nucleophosmin 1 cooperates with the methyltransferase DOT1L to preserve peri-nucleolar heterochromatin organization by regulating H3K27me3 levels and DNA repeats expression	4