OOIR: Observatory of International Research

Papers

(The median citation count of Epigenetics & Chromatin is 5. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Losing DNA methylation at repetitive elements and breaking bad	94
Epigene functional diversity: isoform usage, disordered domain content, and variable binding partners	85
Acquired sperm hypomethylation by gestational arsenic exposure is re-established in both the paternal and maternal genomes of post-epigenetic reprogramming embryos	52
The impact of spatial correlation on methylation entropy with application to mouse brain methylome	44
CpG DNA methylation changes during epididymal sperm maturation in bulls	44
H3K9 post-translational modifications regulate epiblast/primitive endoderm specification in rabbit blastocysts	43
Expression analysis suggests that DNMT3L is required for oocyte de novo DNA methylation only in Muridae and Cricetidae rodents	37
The role of genetic diversity, epigenetic regulation, and sex-based differences in HIV cure research: a comprehensive review	30
Three putative DNA methyltransferases of Verticillium dahliae differentially contribute to DNA methylation that is dispensable for growth, development and virulence	28
Transcriptional regulation mechanism of PARP1 and its application in disease treatment	28
Revealing RCOR2 as a regulatory component of nuclear speckles	27
Telomere-specific chromatin capture using a pyrrole–imidazole polyamide probe for the identification of proteins and non-coding RNAs	26
Differential enrichment of H3K9me3 at annotated satellite DNA repeats in human cell lines and during fetal development in mouse	25
Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation	24
ATAC-seq and RNA-seq analysis unravel the mechanism of sex differentiation and infertility in sex reversal chicken	23
Transcriptional silencing in Saccharomyces cerevisiae: known unknowns	22
Promoter hypermethylation of neural-related genes is compatible with stemness in solid cancers	22
Heterosis of growth trait regulated by DNA methylation and miRNA in allotriploid fish	22
Roles of post-translational modifications of UHRF1 in cancer	22
CUT&Tag applied to zebrafish adult tail fins reveals a return of embryonic H3K4me3 patterns during regeneration	20
The MMP-2 histone H3 N-terminal tail protease is selectively targeted to the transcription start sites of active genes	20
Shedding light on DNA methylation and its clinical implications: the impact of long-read-based nanopore technology	19
The role of MORC3 in silencing transposable elements in mouse embryonic stem cells	18
Functions of HP1 proteins in transcriptional regulation	18
Loss of EZH2-like or SU(VAR)3–9-like proteins causes simultaneous perturbations in H3K27 and H3K9 tri-methylation and associated developmental defects in the fungus Podospora anserina	18

EphrinA5 regulates cell motility by modulating Snhg15/DNA triplex-dependent targeting of DNMT1 to the Ncam1 promoter	15
The role of ribosomal DNA methylation in embryonic development, aging and diseases	15
Analysis of long-range chromatin contacts, compartments and looping between mouse embryonic stem cells, lens epithelium and lens fibers	15
Native and tagged CENP-A histones are functionally inequivalent	14
Changes in chromatin accessibility landscape and histone H3 core acetylation during valproic acid-induced differentiation of embryonic stem cells	14
Phthalates impact on the epigenetic factors contributed specifically by the father at fertilization	14
Impact of chromatin on HIV-1 latency: a multi-dimensional perspective	13
PCGF6/MAX/KDM5D facilitates MAZ/CDK4 axis expression and pRCC progression by hypomethylation of the DNA promoter	13
Shaking up the silence: consequences of HMGN1 antagonizing PRC2 in the Down syndrome brain	13
3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) risk	12
Research progress of SWI/SNF complex in breast cancer	12
The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor	12
Structural comparisons reveal diverse binding modes between nucleosome assembly proteins and histones	12
Pan-cancer predictions of transcription factors mediating aberrant DNA methylation	12
Correction: Dissecting the Kaiso binding profle in clear renal cancer cells	12
Nucleophosmin 1 cooperates with the methyltransferase DOT1L to preserve peri-nucleolar heterochromatin organization by regulating H3K27me3 levels and DNA repeats expression	12
Multiple epigenetic factors co-localize with HMGN proteins in A-compartment chromatin	11
The role of Dmnt1 during spermatogenesis of the insect Oncopeltus fasciatus	11
Assignment of the somatic A/B compartments to chromatin domains in giant transcriptionally active lampbrush chromosomes	11
Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription	11
Ovulatory signal-triggered chromatin remodeling in ovarian granulosa cells by HDAC2 phosphorylation activation-mediated histone deacetylation	11
Manipulating chromatin architecture in C. elegans	10
An optimized approach for multiplexing single-nuclear ATAC-seq using oligonucleotide-conjugated antibodies	10
PDS5A and PDS5B differentially affect gene expression without altering cohesin localization across the genome	10
TP63–TRIM29 axis regulates enhancer methylation and chromosomal instability in prostate cancer	10
MMP-2 is a novel histone H3 N-terminal protease necessary for myogenic gene activation	10
FOSL1 is a key regulator of a super-enhancer driving TCOF1 expression in triple-negative breast cancer	10
Role of sex in immune response and epigenetic mechanisms	9
CREdb: A comprehensive database of Cis-Regulatory Elements and their activity in human cells and tissues	9
Etiology of super-enhancer reprogramming and activation in cancer	9
Altered cfDNA fragmentation profile in hypomethylated regions as diagnostic markers in breast cancer	9
The application of epiphenotyping approaches to DNA methylation array studies of the human placenta	9
Dynamics of cattle sperm sncRNAs during maturation, from testis to ejaculated sperm	8
Histone modification analysis reveals common regulators of gene expression in liver and blood stage merozoites of Plasmodium parasites	8
Knockout tales: the versatile roles of histone H3.3 in development and disease	8
H3K36 methylation reprograms gene expression to drive early gametocyte development in Plasmodium falciparum	8
From compartments to loops: understanding the unique chromatin organization in neuronal cells	8
The transgenic IG-DMR sequence of the mouse Dlk1-Dio3 domain acquired imprinted DNA methylation during the post-fertilization period	8
Multilevel interrogation of H3.3 reveals a primordial role in transcription regulation	8
AF10 (MLLT10) prevents somatic cell reprogramming through regulation of DOT1L-mediated H3K79 methylation	8
Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation	8
Analyses of POL30 (PCNA) reveal positional effects in transient repression or bi-modal active/silent state at the sub-telomeres of S. cerevisiae	8
Efficient generation of epigenetic disease model mice by epigenome editing using the piggyBac transposon system	7
Structural and functional specificity of H3K36 methylation	7
Physical exercise and epigenetic modifications in skeletal muscle, brain, and heart	7
Su(Hw) interacts with Combgap to establish long-range chromatin contacts	7
Epigenetic control of dental stem cells: progress and prospects in multidirectional differentiation	7
Maternal SMCHD1 controls both imprinted Xist expression and imprinted X chromosome inactivation	7
A polycomb group protein EED epigenetically regulates responses in lipopolysaccharide tolerized macrophages	7
Dissecting the Kaiso binding profile in clear renal cancer cells	7

Co-effects of m6A and chromatin accessibility dynamics in the regulation of cardiomyocyte differentiation	6
Effects of paternal exposure to cigarette smoke on sperm DNA methylation and long-term metabolic syndrome in offspring	6
Crosstalk between metabolism and epigenetics during macrophage polarization	6
PARP-dependent and NAT10-independent acetylation of N4-cytidine in RNA appears in UV-damaged chromatin	6
Epigenetic rewriting at centromeric DNA repeats leads to increased chromatin accessibility and chromosomal instability	6
Mechanism of non-coding RNA regulation of DNMT3A	6
The solid and liquid states of chromatin	6
PRKACB is a novel imprinted gene in marsupials	6
Mitochondrial supplementation of Sus scrofa metaphase II oocytes alters DNA methylation and gene expression profiles of blastocysts	6
Crosstalk between non-coding RNAs and programmed cell death in colorectal cancer: implications for targeted therapy	5
The zinc finger protein CLAMP promotes long-range chromatin interactions that mediate dosage compensation of the Drosophila male X-chromosome	5
Evolutionary adaptation of the Polycomb repressive complex 2	5
Epigenetic modifier alpha-ketoglutarate modulates aberrant gene body methylation and hydroxymethylation marks in diabetic heart	5
Assessment of relationships between epigenetic age acceleration and multiple sclerosis: a bidirectional mendelian randomization study	5
O-GlcNAcylation: the sweet side of epigenetics	5
Correction: Characterizing chromatin interactions of regulatory elements and nucleosome positions, using Hi‑C, Micro‑C, and promoter capture Micro‑C	5
Folate deficiency reduced aberrant level of DOT1L-mediated histone H3K79 methylation causes disruptive SHH gene expression involved in neural tube defects	5
Making sense of the linear genome, gene function and TADs	5
Sequencing of methylase-accessible regions in integral circular extrachromosomal DNA reveals differences in chromatin structure	5