Genome Medicine

Article	Citations
STModule: identifying tissue modules to uncover spatial components and characteristics of transcriptomic landscapes	512
The genetics and epidemiology of N- and O-immunoglobulin A glycomics	434
Neoantigen DNA vaccines are safe, feasible, and induce neoantigen-specific immune responses in triple-negative breast cancer patients	195
Multi-omics uncovers immune-modulatory molecules in plasma contributing to resistance exercise-ameliorated locomotor disability after incomplete spinal cord injury	162
Integrating pharmacogenomics and cheminformatics with diverse disease phenotypes for cell type-guided drug discovery	157
Destination shapes antibiotic resistance gene acquisitions, abundance increases, and diversity changes in Dutch travelers	154
Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance	152
Comprehensive genomic and tumour immune profiling reveals potential therapeutic targets in malignant pleural mesothelioma	149
Spatial transcriptome profiling identifies DTX3L and BST2 as key biomarkers in esophageal squamous cell carcinoma tumorigenesis	143
Demonstrating trustworthiness when collecting and sharing genomic data: public views across 22 countries	131
Circulating bacterial signature is linked to metabolic disease and shifts with metabolic alleviation after bariatric surgery	117
An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility	114
Systems pharmacogenomics identifies novel targets and clinically actionable therapeutics for medulloblastoma	114
Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants	108
Non-cancer-related pathogenic germline variants and expression consequences in ten-thousand cancer genomes	101
Whole genome sequencing-based classification of human-related Haemophilus species and detection of antimicrobial resistance genes	98
Single-cell exome sequencing reveals multiple subclones in metastatic colorectal carcinoma	96
Identification of a cytokine-dominated immunosuppressive class in squamous cell lung carcinoma with implications for immunotherapy resistance	92
Landscape and selection of vaccine epitopes in SARS-CoV-2	92
Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19	91
A mixture model for signature discovery from sparse mutation data	89
Transcriptomic perspectives of memory-like NK cells and aging	88
African-specific alleles modify risk for asthma at the 17q12-q21 locus in African Americans	87
The role of genetic testing in diagnosis and care of inherited cardiac conditions in a specialised multidisciplinary clinic	85
Clinical utility of periodic reinterpretation of CNVs of uncertain significance: an 8-year retrospective study	79

Loss of Y in leukocytes as a risk factor for critical COVID-19 in men	79
Pervasiveness of HLA allele-specific expression loss across tumor types	79
ReporTree: a surveillance-oriented tool to strengthen the linkage between pathogen genetic clusters and epidemiological data	74
A machine learning classifier using 33 host immune response mRNAs accurately distinguishes viral and non-viral acute respiratory illnesses in nasal swab samples	72
Combining optical genome mapping and RNA-seq for structural variants detection and interpretation in unsolved neurodevelopmental disorders	70
Circular RNA landscape in extracellular vesicles from human biofluids	66
Curating genomic disease-gene relationships with Gene2Phenotype (G2P)	66
In vivo genome editing in mouse restores dystrophin expression in Duchenne muscular dystrophy patient muscle fibers	63
Untargeted metabolomic profiling reveals molecular signatures associated with type 2 diabetes in Nigerians	60
Germline HLA-B evolutionary divergence influences the efficacy of immune checkpoint blockade therapy in gastrointestinal cancer	60
Leveraging new methods for comprehensive characterization of mitochondrial DNA in esophageal squamous cell carcinoma	57
The exceptions that prove the rule—a historical view of bedaquiline susceptibility	57
Genome sequencing as a generic diagnostic strategy for rare disease	56
Rare subclonal sequencing of breast cancers indicates putative metastatic driver mutations are predominately acquired after dissemination	55
Meta-analysis identifies common gut microbiota associated with multiple sclerosis	55
A validated heart-specific model for splice-disrupting variants in childhood heart disease	54
Variability of polygenic prediction for body mass index in Africa	54
ENU-based dominant genetic screen identifies contractile and neuronal gene mutations in congenital heart disease	54
PheSeq, a Bayesian deep learning model to enhance and interpret the gene-disease association studies	53
Using multiplexed functional data to reduce variant classification inequities in underrepresented populations	53
Knockout mice with pituitary malformations help identify human cases of hypopituitarism	52
Analysis of admixed Greenlandic siblings shows that the mean genotypic values for metabolic phenotypes differ between Inuit and Europeans	52
Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative	51
Epigenetic age and long-term cancer risk following a stroke	51
Systematic genomic analysis of SARS-CoV-2 co-infections throughout the pandemic and segregation of the strains involved	50
Towards elucidating disease-relevant states of neurons and glia by CRISPR-based functional genomics	50
Long-read sequencing identifies a common transposition haplotype predisposing for CLCNKB deletions	50
ClinPrior: an algorithm for diagnosis and novel gene discovery by network-based prioritization	50
Identification of specific susceptibility loci for the early-onset colorectal cancer	50
Polygenic risk scores for disease risk prediction in Africa: current challenges and future directions	49
Loss of p53-DREAM-mediated repression of cell cycle genes as a driver of lymph node metastasis in head and neck cancer	48
The role of admixture in the rare variant contribution to inflammatory bowel disease	48
The impact of damaging epilepsy and cardiac genetic variant burden in sudden death in the young	47
Systematic analysis of Mendelian disease-associated gene variants reveals new classes of cancer-predisposing genes	47
Author Correction: Leveraging genomic diversity for discovery in an electronic health record linked biobank: the UCLA ATLAS Community Health Initiative	46
Metagenomic prediction of antimicrobial resistance in critically ill patients with lower respiratory tract infections	45
Correction: Applicability of epigenetic age models to next-generation methylation arrays	45
Long-read sequencing reveals the landscape of aberrant alternative splicing and novel therapeutic target in colorectal cancer	45
Beyond the exome: utility of long-read whole genome sequencing in exome-negative autosomal recessive diseases	44
Return of non-ACMG recommended incidental genetic findings to pediatric patients: considerations and opportunities from experiences in genomic sequencing	44
Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer	43
Early detection of hepatocellular carcinoma via no end-repair enzymatic methylation sequencing of cell-free DNA and pre-trained neural network	42
Annotation of cell types (ACT): a convenient web server for cell type annotation	42
A dynamic single cell-based framework for digital twins to prioritize disease genes and drug targets	41
Diversity of CFTR variants across ancestries characterized using 454,727 UK biobank whole exome sequences	41
Metabolic control by the microbiome	40
GenTB: A user-friendly genome-based predictor for tuberculosis resistance powered by machine learning	40
Effectiveness and safety of Bifidobacterium and berberine in human hyperglycemia and their regulatory effect on the gut microbiota: a multi-center, double-blind, randomized, parallel-controlled study	40
Genome-aware annotation of CRISPR guides validates targets in variant cell lines and enhances discovery in screens	40
Optimizing Nanopore sequencing-based detection of structural variants enables individualized circulating tumor DNA-based disease monitoring in cancer patients	40

Automated prioritization of sick newborns for whole genome sequencing using clinical natural language processing and machine learning	40
Acute ischemia induces spatially and transcriptionally distinct microglial subclusters	39
Correction: Intricate interplay of CRISPR-Cas systems, anti-CRISPR proteins, and antimicrobial resistance genes in a globally successful multi-drug resistant Klebsiella pneumoniae clone	39
Single-molecule methylation profiles of cell-free DNA in cancer with nanopore sequencing	39
Intricate interplay of CRISPR-Cas systems, anti-CRISPR proteins, and antimicrobial resistance genes in a globally successful multi-drug resistant Klebsiella pneumoniae clone	39
Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women	39
Epigenome-wide association study of kidney function identifies trans-ethnic and ethnic-specific loci	38
A guide for the diagnosis of rare and undiagnosed disease: beyond the exome	38
The genomic landscape of rare disorders in the Middle East	37
The gut microbiota in multiple sclerosis varies with disease activity	37
Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA	36
Machine learning integrative approaches to advance computational immunology	36
Deep learning in cancer genomics and histopathology	36
Post-vaccine epidemiology of serotype 3 pneumococci identifies transformation inhibition through prophage-driven alteration of a non-coding RNA	36
Single-cell transcriptomics reveals common epithelial response patterns in human acute kidney injury	35
Multi-site tumor sampling highlights molecular intra-tumor heterogeneity in malignant pleural mesothelioma	35
Metatranscriptomic profiling reveals pathogen and host response signatures of pediatric acute sinusitis and upper respiratory infection	35
IFN-γ and TNF-α drive a CXCL10+ CCL2+ macrophage phenotype expanded in severe COVID-19 lungs and inflammatory diseases with tissue inflammation	35
DNA demethylation triggers cell free DNA release in colorectal cancer cells	35
Prospective high-throughput genome profiling of advanced cancers: results of the PERMED-01 clinical trial	35
An introduction to spatial transcriptomics for biomedical research	35
A polygenic score for height identifies an unmeasured genetic predisposition among pediatric patients with idiopathic short stature	34
Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities	34
Whole genome sequencing across clinical trials identifies rare coding variants in GPR68 associated with chemotherapy-induced peripheral neuropathy	34
Clinical evaluation of long-read sequencing-based episignature detection in developmental disorders	34
The landcape of Helicobacter pylori-mediated DNA breaks links bacterial genotoxicity to its oncogenic potential	34
Emerging genetic complexity and rare genetic variants in neurodegenerative brain diseases	33
Efficacy and safety of novel multiple-chain DAP-CAR-T cells targeting mesothelin in ovarian cancer and mesothelioma: a single-arm, open-label and first-in-human study	33
Correction to: Whole genome sequencing-based classifcation of human-related Haemophilus species and detection of antimicrobial resistance genes	33
Correction: Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing	33
Long-term persistence of diverse clones shapes the transmission landscape of invasive Listeria monocytogenes	32
Somatic mutational profiles and germline polygenic risk scores in human cancer	32
Analysis of 3760 hematologic malignancies reveals rare transcriptomic aberrations of driver genes	32
Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes	32
pVACview: an interactive visualization tool for efficient neoantigen prioritization and selection	32
Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer	31
Genomic surveillance of multidrug-resistant organisms based on long-read sequencing	31
Patient-derived xenograft models capture genomic heterogeneity in endometrial cancer	31
Novel temporal and spatial patterns of metastatic colonization from breast cancer rapid-autopsy tumor biopsies	31
Rare deleterious mutations of HNRNP genes result in shared neurodevelopmental disorders	31
Human liver single nucleus and single cell RNA sequencing identify a hepatocellular carcinoma-associated cell-type affecting survival	30
Genome-wide analyses of multiple obesity-related cytokines and hormones informs biology of cardiometabolic traits	30
An epigenetic and transcriptomic signature of immune tolerance in human monocytes through multi-omics integration	30
The vaginal microbiota and innate immunity after local excisional treatment for cervical intraepithelial neoplasia	30
Evaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units	30
A global cancer data integrator reveals principles of synthetic lethality, sex disparity and immunotherapy	30
Constructing germline research cohorts from the discarded reads of clinical tumor sequences	29
Publisher Correction: Analysis of transcriptomic features reveals molecular endotypes of SLE with clinical implications	29
Genomic architecture of autism spectrum disorder in Qatar: The BARAKA-Qatar Study	29
A pan-cancer landscape of telomeric content shows that RAD21 and HGF alterations are associated with longer telomeres	29
Evaluating the use of paralogous protein domains to increase data availability for missense variant classification	29
Mendelian gene identification through mouse embryo viability screening	28
Non-canonical antigens are the largest fraction of peptides presented by MHC class I in mismatch repair deficient murine colorectal cancer	28
The emergence of highly resistant and hypervirulent Klebsiella pneumoniae CC14 clone in a tertiary hospital over 8 years	28
De novo identification of expressed cancer somatic mutations from single-cell RNA sequencing data	28
CTpathway: a CrossTalk-based pathway enrichment analysis method for cancer research	28
SRT-Server: powering the analysis of spatial transcriptomic data	28
ACT-Discover: identifying karyotype heterogeneity in pancreatic cancer evolution using ctDNA	27
Universal clinical Parkinson’s disease axes identify a major influence of neuroinflammation	27
Prostate cancers with distinct transcriptional programs in Black and White men	27
Mechanistic insights into the interactions between cancer drivers and the tumour immune microenvironment	27
Intra-prostatic tumour evolution, steps in metastatic spread and histogenomic associations revealed by integration of multi-region whole-genome sequencing with histopathological features	27
An atlas of cell-type-specific interactome networks across 44 human tumor types	27
The multiple de novo copy number variant (MdnCNV) phenomenon presents with peri-zygotic DNA mutational signatures and multilocus pathogenic variation	27
Ancestry-driven metabolite variation provides insights into disease states in admixed populations	27
Novel genetic markers for chronic kidney disease in a geographically isolated population of Indigenous Australians: Individual and multiple phenotype genome-wide association study	27
Smoking-associated gene expression alterations in nasal epithelium reveal immune impairment linked to lung cancer risk	26
Nanopore-based random genomic sampling for intraoperative molecular diagnosis	26
Interaction of bacterial genera associated with therapeutic response to immune checkpoint PD-1 blockade in a United States cohort	26
Spatial intra-tumour heterogeneity and treatment-induced genomic evolution in oesophageal adenocarcinoma: implications for prognosis and therapy	26
SenPred: a single-cell RNA sequencing-based machine learning pipeline to classify deeply senescent dermal fibroblast cells for the detection of an in vivo senescent cell burden	26
Combined exome and transcriptome sequencing of non-muscle-invasive bladder cancer: associations between genomic changes, expression subtypes, and clinical outcomes	26
INSaFLU-TELEVIR: an open web-based bioinformatics suite for viral metagenomic detection and routine genomic surveillance	26
Spatial multi-omics: novel tools to study the complexity of cardiovascular diseases	26
Spatially resolved transcriptomic profiles reveal unique defining molecular features of infiltrative 5ALA-metabolizing cells associated with glioblastoma recurrence	25
Role of the intestinal microbiome and microbial-derived metabolites in immune checkpoint blockade immunotherapy of cancer	25
Metronidazole response profiles of Gardnerella species are congruent with phylogenetic and comparative genomic analyses	25
A meta-analysis of immune-cell fractions at high resolution reveals novel associations with common phenotypes and health outcomes	25
A new method for detecting mixed Mycobacterium tuberculosis infection and reconstructing constituent strains provides insights into transmission	25
Meiotic and mitotic aneuploidies drive arrest of in vitro fertilized human preimplantation embryos	25

Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis	24
Molecular profiling of human non-small cell lung cancer by single-cell RNA-seq	24
Large-scale discovery of novel neurodevelopmental disorder-related genes through a unified analysis of single-nucleotide and copy number variants	24
Ethnic variations in metabolic syndrome components and their associations with the gut microbiota: the HELIUS study	24
A lepidic gene signature predicts patient prognosis and sensitivity to immunotherapy in lung adenocarcinoma	24
Identification and drug-induced reversion of molecular signatures of Alzheimer’s disease onset and progression in AppNL-G-F, AppNL-F, and 3xTg-AD mouse models	24
Human reference gut microbiome catalog including newly assembled genomes from under-represented Asian metagenomes	24
Whole genome sequencing reveals the independent clonal origin of multifocal ileal neuroendocrine tumors	23
Shared genetic architecture between irritable bowel syndrome and psychiatric disorders reveals molecular pathways of the gut-brain axis	23
Longitudinal multi-omics study of palbociclib resistance in HR-positive/HER2-negative metastatic breast cancer	23
Assessing the clinical utility of protein structural analysis in genomic variant classification: experiences from a diagnostic laboratory	23
Crosstalk between microRNA expression and DNA methylation drives the hormone-dependent phenotype of breast cancer	23
Application of exome sequencing for prenatal diagnosis of fetal structural anomalies: clinical experience and lessons learned from a cohort of 1618 fetuses	23
Whole-genome sequencing as an investigational device for return of hereditary disease risk and pharmacogenomic results as part of the All of Us Research Program	23
Novel functional insights into ischemic stroke biology provided by the first genome-wide association study of stroke in indigenous Africans	22
The lung microbiome, peripheral gene expression, and recurrence-free survival after resection of stage II non-small cell lung cancer	22
Polygenic scores for longitudinal prediction of incident type 2 diabetes in an ancestrally and medically diverse primary care physician network: a patient cohort study	22
An international policy on returning genomic research results	22
High-throughput functional mapping of variants in an arrhythmia gene, KCNE1, reveals novel biology	22
Distinct transcriptional programs stratify ovarian cancer cell lines into the five major histological subtypes	22
STopover captures spatial colocalization and interaction in the tumor microenvironment using topological analysis in spatial transcriptomics data	22
Systematic comparison of published host gene expression signatures for bacterial/viral discrimination	22
Integrated analysis of single-cell and bulk RNA sequencing data reveals a pan-cancer stemness signature predicting immunotherapy response	22
Tumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing	22
Single-cell analysis of immune and stroma cell remodeling in clear cell renal cell carcinoma primary tumors and bone metastatic lesions	22
Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations	22
Unsupervised spatially embedded deep representation of spatial transcriptomics	22
Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts	22
Nanopore sequencing with unique molecular identifiers enables accurate mutation analysis and haplotyping in the complex lipoprotein(a) KIV-2 VNTR	21
Single-cell RNA-seq reveals alterations in peripheral CX3CR1 and nonclassical monocytes in familial tauopathy	21
Beyond gene-disease validity: capturing structured data on inheritance, allelic requirement, disease-relevant variant classes, and disease mechanism for inherited cardiac conditions	21
Functional genomic analysis delineates regulatory mechanisms of GWAS-identified bipolar disorder risk variants	21
Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia	21
A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer’s disease	21
Pre-operative clonal hematopoiesis is related to adverse outcome in lung cancer after adjuvant therapy	21
Mendelian randomization analyses suggest a causal role for circulating GIP and IL-1RA levels in homeostatic model assessment-derived measures of β-cell function and insulin sensitivity in Africans wit	20
Biological basis of extensive pleiotropy between blood traits and cancer risk	20
Neutralization sensitivity, fusogenicity, and infectivity of Omicron subvariants	20
Transcriptional signals of transformation in human cancer	20
Variant-specific pathophysiological mechanisms of AFF3 differently influence transcriptome profiles	20
Sequencing individual genomes with recurrent genomic disorder deletions: an approach to characterize genes for autosomal recessive rare disease traits	20
Comprehensive assessment of the genetic characteristics of small for gestational age newborns in NICU: from diagnosis of genetic disorders to prediction of prognosis	20
Combining a prioritization strategy and functional studies nominates 5’UTR variants underlying inherited retinal disease	20
A genetic model for central chondrosarcoma evolution correlates with patient outcome	20
Transcriptional signatures of the BCL2 family for individualized acute myeloid leukaemia treatment	20
Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma	19
Application of a framework to guide genetic testing communication across clinical indications	19
Ultra-low-coverage genome-wide association study—insights into gestational age using 17,844 embryo samples with preimplantation genetic testing	19
Pharmacogenomic profiling reveals molecular features of chemotherapy resistance in IDH wild-type primary glioblastoma	19
High level of complexity and global diversity of the 3q29 locus revealed by optical mapping and long-read sequencing	19
Finding associations in a heterogeneous setting: statistical test for aberration enrichment	18
Impact of rare and common genetic variation in the interleukin-1 pathway on human cytokine responses	18
Advancing precision public health using human genomics: examples from the field and future research opportunities	18
Integrative statistical analyses of multiple liquid biopsy analytes in metastatic breast cancer	18
Combinatorial patterns of gene expression changes contribute to variable expressivity of the developmental delay-associated 16p12.1 deletion	18
Gain and loss of TASK3 channel function and its regulation by novel variation cause KCNK9 imprinting syndrome	17
Genome-wide association studies identify novel genetic loci for epigenetic age acceleration among survivors of childhood cancer	17
Rapid whole genome sequencing of critically ill pediatric patients from genetically underrepresented populations	17
Predicting heterogeneity in clone-specific therapeutic vulnerabilities using single-cell transcriptomic signatures	17
Comprehensive multi-omics integration identifies differentially active enhancers during human brain development with clinical relevance	17
Diversity in EWAS: current state, challenges, and solutions	17
Functional pre-therapeutic evaluation by genome editing of variants of uncertain significance of essential tumor suppressor genes	17
DevKidCC allows for robust classification and direct comparisons of kidney organoid datasets	17
Functional significance of gain-of-function H19 lncRNA in skeletal muscle differentiation and anti-obesity effects	17
Using single-nucleus RNA-sequencing to interrogate transcriptomic profiles of archived human pancreatic islets	17
Ontology-aware deep learning enables ultrafast and interpretable source tracking among sub-million microbial community samples from hundreds of niches	16
Genetic subtypes, allelic effects, and convergent neurodevelopmental mechanisms	16
Historic methicillin-resistant Staphylococcus aureus: expanding current knowledge using molecular epidemiological characterization of a Swiss legacy collection	16
Preventing disease progression in multiple sclerosis—insights from large real-world cohorts	16
Integrative analysis of spatial and single-cell transcriptome data from human pancreatic cancer reveals an intermediate cancer cell population associated with poor prognosis	16
Genomic and transcriptomic features between primary and paired metastatic fumarate hydratase–deficient renal cell carcinoma	16
Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers	16
Full-spectral genome analysis of natural killer/T cell lymphoma highlights impacts of genome instability in driving its progression	16
Metabolome-wide Mendelian randomization for age at menarche and age at natural menopause	15
Identification of pathological pathways centered on circRNA dysregulation in association with irreversible progression of Alzheimer’s disease	15
Pathological mechanisms and candidate therapeutic approaches in the hearing loss of mice carrying human MIR96 mutations	15
Correction: Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women	15
Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathy	15
Multiomic integration analysis identifies atherogenic metabolites mediating between novel immune genes and cardiovascular risk	15
Structural variant allelic heterogeneity in MECP2 duplication syndrome provides insight into clinical severity and variability of disease expression	15
Single-nucleus RNA sequencing of human pancreatic islets identifies novel gene sets and distinguishes β-cell subpopulations with dynamic transcriptome profiles	15
Correction to: Novel risk genes and mechanisms implicated by exome sequencing of 2572 individuals with pulmonary arterial hypertension	15
Cardiomyopathies in 100,000 genomes project: interval evaluation improves diagnostic yield and informs strategies for ongoing gene discovery	15
Tracing carriage, acquisition, and transmission of ESBL-producing Escherichia coli over two years in a tertiary care hospital	15
Comprehensive pathogen identification and antimicrobial resistance prediction from positive blood cultures using nanopore sequencing technology	15
Correction: Genome Med 15, 115 & Genome Med 16, 3	15
Integrated genomic analyses of acral and mucosal melanomas nominate novel driver genes	15
Ganciclovir-induced mutations are present in a diverse spectrum of post-transplant malignancies	15
The genomic architecture of EBV and infected gastric tissue from precursor lesions to carcinoma	14
Integration of genetic, transcriptomic, and clinical data provides insight into 16p11.2 and 22q11.2 CNV genes	14
Long-read sequencing identifies copy-specific markers of SMN gene conversion in spinal muscular atrophy	14
Structural variants linked to Alzheimer’s disease and other common age-related clinical and neuropathologic traits	14
Location and condition based reconstruction of colon cancer microbiome from human RNA sequencing data	14
Integrated single-cell analysis reveals distinct epigenetic-regulated cancer cell states and a heterogeneity-guided core signature in tamoxifen-resistant breast cancer	14
Deletion of a non-canonical regulatory sequence causes loss of Scn1a expression and epileptic phenotypes in mice	14