OOIR: Observatory of International Research

Papers

(The TQCC of EMBO Molecular Medicine is 31. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-08-01 to 2026-08-01.)

Article	Citations
Whole‐brain microscopy reveals distinct temporal and spatial efficacy of anti‐Aβ therapies	247
Targetable Brg1‐CXCL14 axis contributes to alcoholic liver injury by driving neutrophil trafficking	195
Elongator and the role of its subcomplexes in human diseases	127
HIF2α activation and mitochondrial deficit due to iron chelation cause retinal atrophy	97
Targeting conformational changes in C‐reactive protein to inhibit pro‐inflammatory actions	94
Depressive patient‐derived GABA interneurons reveal abnormal neural activity associated with HTR2C	85
TFEB and TFE3 drive kidney cystogenesis and tumorigenesis	82
IQCN disruption causes fertilization failure and male infertility due to manchette assembly defect	80
Eosinophil‐derived IL‐4 is necessary to establish the inflammatory structure in innate inflammation	72
Metformin rescues migratory deficits of cells derived from patients with periventricular heterotopia	70
Molecular and cognitive signatures of ageing partially restored through synthetic delivery of IL2 to the brain	68
Diagnostic biomarkers for active tuberculosis: progress and challenges	68
ASO targeting RBM3 temperature‐controlled poison exon splicing prevents neurodegeneration in vivo	65
Systemic inflammation after stroke: implications for post‐stroke comorbidities	61
Nerve regeneration by interferon intervention in aging brain	60
Shear stress control of vascular leaks and atheromas through Tie2 activation by VE‐PTP sequestration	58
Autosomal recessive pathogenic MSTO1 variants in hereditary optic atrophy	57
Active immunotherapy reduces NOTCH3 deposition in brain capillaries in a CADASIL mouse model	54
Single‐cell profiling of muscle‐infiltrating T cells in idiopathic inflammatory myopathies	53
Functions of double‐negative B cells in autoimmune diseases, infections, and cancers	53
An ACE2 decoy can be administered by inhalation and potently targets omicron variants of SARS‐CoV‐2	53
Blocking STAT3/5 through direct or upstream kinase targeting in leukemic cutaneous T‐cell lymphoma	52
Macrophage colony‐stimulating factor as a weapon against cytomegalovirus	51
Looking at a baby's heart through the lens of the mother's blood	51
Optimizing the Cas13 antiviral train: cargo and delivery	47

TOP3A amplification and ATRX inactivation are mutually exclusive events in pediatric osteosarcomas using ALT	45
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy	45
In vivo single‐cell transcriptomics reveal Klebsiella pneumoniae skews lung macrophages to promote infection	44
Sex differences and risk factors for bleeding in Alagille syndrome	44
Advances in high‐throughput mass spectrometry in drug discovery	44
Immuno(T)herapy for age‐related diseases	43
X‐linked inhibitor of apoptosis protein represents a promising therapeutic target for relapsed/refractory ALL	43
The molecular biology of peritoneal metastatic disease	42
The human host response to monkeypox infection: a proteomic case series study	42
Elucidating effects of environmental exposure using human‐induced pluripotent stem cell disease modeling	39
AAV induces hepatic necroptosis and carcinoma in diabetic and obese mice dependent on Pebp1 pathway	38
Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation	38
Nanobody‐mediated complement activation to kill HIV‐infected cells	37
Functional analysis reveals driver cooperativity and novel mechanisms in endometrial carcinogenesis	37
IL‐27 produced during acute malaria infection regulates Plasmodium‐specific memory CD4+ T cells	36
miR‐181a/b downregulation: a mutation‐independent therapeutic approach for inherited retinal diseases	36
Systemic gene therapy rescues retinal dysfunction and hearing loss in a model of Norrie disease	35
Trichothiodystrophy‐associated MPLKIP maintains DBR1 levels for proper lariat debranching and ectodermal differentiation	34
Answer to Gerber et al. “Autosomal recessive pathogenic MSTO1 variants in hereditary optic atrophy”	34
NRF3 suppresses squamous carcinogenesis, involving the unfolded protein response regulator HSPA5	33
Viral anti‐inflammatory serpin reduces immuno‐coagulopathic pathology in SARS‐CoV‐2 mouse models of infection	33
Development of allogeneic iPS cell‐based therapy: from bench to bedside	33
Unravelling homologous recombination repair deficiency and therapeutic opportunities in soft tissue and bone sarcoma	32
Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodies	32
Nuclear PRMT5 is a biomarker of sensitivity to tamoxifen in ERα+ breast cancer	32
Full eradication of pre‐clinical human papilloma virus‐induced tumors by a lentiviral vaccine	32
Patient‐ and xenograft‐derived organoids recapitulate pediatric brain tumor features and patient treatments	31
TAPT1—at the crossroads of extracellular matrix and signaling in Osteogenesis imperfecta	31