Bioanalysis

Article	Citations
A Brave New World?	31
Meet the Editorial Board – An Interview with Min Meng and Transitions from Small Regional Labs to Global CRO	28
Biomarker Context-Of-Use: How Organizational Design Can Impact the Implementation of the Appropriate Biomarker Assay Strategy	27
Biomonitoring of Arsenic, Lead, Manganese and Mercury in Hair from a Presumably Exposed Uruguayan Child Population	26
Adopting ambient ionization mass spectrometry into bioanalytical laboratories	24
Signal-to-noise Ratio to Assess Magnitude, Kinetics and Impact on Pharmacokinetics of the Immune Response to an Adalimumab Biosimilar	22
Peripheral blood mononuclear cells isolation from mouse and rabbit blood to quantify active nucleotide and define brincidofovir dose for smallpox	22
Degradation of Vancomycin in External Quality Assessment Samples is a Factor to Underestimate Its Concentration	21
Simple Method to Determine the Concentration and Incorporation Ratio of Ruthenium-Labeled Antibodies	19
Volumetric Absorptive Microsampling as An Effective Microsampling Technique for LC–MS/MS Bioanalysis of Biomarkers in Drug Discovery	19
Bioanalysis by LC-MS/MS and Preclinical Pharmacokinetic Interaction Study of Ribociclib and Oleanolic Acid	19
Uncovering the Green Frontier: Harnessing Deep Eutectic Solvents for Sustainable Bioanalysis	18
High-Sensitivity Workflow for LC–MS-Based Analysis of GALNAC-Conjugated Oligonucleotides: A Case Study	17
Iron oxide nanozymes as versatile analytical tools: an overview of their application as detection technique	17
Validation of Enantioseparation and Quantitation of an Active Metabolite of Abrocitinib in Human Plasma	14
Patient-centric clinical trials: collaboration and innovation in bioanalytical and clinical operations	14
Determination of IQZ23 in Rat Plasma using LC-MS/MS: Consideration for Matrix Effect and Internal Standard Interference	14
Determination of carbamazepine in fingerprints: a feasibility study to evaluate adherence in epilepsy patients	13
Handling Unstable Analytes: Literature Review and Expert Panel Survey by the Japan Bioanalysis Forum Discussion Group	13
Comparison of Assay Formats Used for the Detection of Pre-Existing Anti-Drug Antibodies Against Monoclonal Antibodies	12
Whole blood stability in bioanalytical method validation: updated recommendations from the European Bioanalysis Forum	12
Diversity and Inclusion in the Bioanalytical Industry: An Interview with Anahita Keyhani	12
Strategy and Validation of a Nonclinical Generic Plug-and-Play Antidrug Antibody Method for Human Monoclonal Antibody Biotherapeutics	12
A comparison of branched DNA and reverse transcriptase quantitative polymerase chain reaction methodologies for quantitation of lipid nanoparticle encapsulated mRNA	12
Recent advances in gold nanoparticle-based colorimetric aptasensors for chemical and biological analyses	12

Ligand-binding assays vs chromatographic platforms for oligonucleotide quantification	11
Simultaneous Measurement of Mouse and Human Albumin in Chimeric Mice with Humanized Livers	11
Bioanalysis Rising Star Award 2024: interviews with the finalists	11
Validation of an LC–MS/MS method for the determination of sotorasib, a KRAS G12C inhibitor, in human plasma	11
The investigation of connection between anticoagulant therapy and vitamin K homologues in human determined by LC–MS/MS	11
A novel LC-MS/MS method for simultaneous estimation of chlordiazepoxide and clidinium in human plasma and its application to pharmacokinetic assessment	10
Transforming drug discovery: the impact of AI and molecular simulation on R&D efficiency	10
Special Focus Issue - Covid-19: Bioanalytical Considerations, Contributions and Lessons – Part 2	10
Bioanalysis of free antisense oligonucleotide payload from antibody–oligonucleotide conjugate by hybridization LC-MS/MS	9
Considerations in Designing and Implementing a Bioanalytical Contract Research Organization Key Performance Indicator System	9
Perspectives on a Flexible Strategy for the Management of Nonregulated Bioanalysis	9
An LC–MS/MS Method for Simultaneous Determination of LB-100 and Its Active Metabolite, Endothall, in Human Plasma	9
Western Blotting: Evolution of an Old Analytical Method To a New Quantitative Tool for Biomarker Measurements	8
Olympic Anti-Doping Laboratory: The Analytical Technological Road From 2016 Rio De Janeiro to 2021 Tokyo	8
Upfront Acid Treatment with Low Final pH: The Development and Testing of a Novel Method to Improve Drug Tolerance in Antidrug Antibody Assays	8
Inception and Development of a LC–MS/MS Assay for the Multiplexed Quantitation of Nine Human Drug Transporter Biomarkers	8
Determination of meropenem in capillary plasma microsamples using LC–MS/MS	8
Method development for the quantification of lead levels in whole blood sampled on Mitra ® with VAMS ® tips by inductively coupled	8
Novel Isoelectric Target Depletion (ITaD) Protocol Reduces the Need for Specific Reagents for Immunogenicity Testing	8
Highlights of the 15th Japan Bioanalysis Forum Symposium	8
Highlights of the 13th Japan Bioanalysis Forum Symposium	8
Development and Validation of qPCR Methods for Nucleic Acid Biomarkers as a Drug Development Tool: Points to Consider	8
Determination of Amphetamines, Opioids, Cocaine Metabolites and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in Urine Using Biocompatible Solid-Phase Microextraction and Ultra-Performance LC–MS/MS	7
High Ionic Strength Dissociation Assay Reduces Dimeric Target Interference in Immunogenicity Testing	7
Molecularly Imprinted Electrochemical Biosensor for Thrombin Detection by Comparing Different Monomers	7
DoE-assisted HPLC method development and validation of enzalutamide and repaglinide in rat plasma	7
COVID-19’s Impact on Bioanalytical Labs	7
A Sensitive, Robust and High-Throughput Isotope Dilution LC–MS/MS Method for Quantifying Three Folate Forms in Serum	7
Internal standard variability: root cause investigation, parallelism for evaluating trackability and practical considerations	7
Comparison of multiple bioanalytical assay platforms for the quantitation of siRNA therapeutics	7
Development of an LC-MS/MS assay to analyze a lipid-conjugated siRNA by solid phase extraction (SPE) in mouse plasma and tissue using a stable isotope labeled internal standard (SILIS)	7
Validation of UV–Vis spectrophotometric colorimetric methods for Rifampicin quantification in PBS & biological matrices	7
Special Focus Issue - Performing Flow Cytometry in Clinical Trials	7
Critical Reagent Inventory Management System and Web Portal Specifically Optimized for Supporting External Clients	7
Biopharmaceutical Quality Control with Mass Spectrometry	6
Quantitation of BCAA and BCKA in plasma and patient-centric dried blood microsamples in a clinical setting	6
Development and validation of bioanalytical methods to support clinical study of disitamab vedotin	6
Ocular Bioanalysis of Moxifloxacin and Ketorolac Tromethamine in Rabbit Lacrimal Matrix Using Liquid Chromatography–Tandem Mass Spectrometry	6
An Eco-Friendly Ultra-Performance Liquid Chromatography–Mass Spectrometry Method for Quantification of Rivaroxaban and Ticagrelor in Rat Plasma: Grapefruit Interactions	6
HPLC Method for Simultaneous Estimation of Paclitaxel and Baicalein: Pharmaceutical and Pharmacokinetic Applications	6
Revolutionizing depression diagnosis: earwax analysis for cortisol and beyond	6
Cytochrome P450 Enzymes: A Review on Drug Metabolizing Enzyme Inhibition Studies in Drug Discovery and Development	6
Perspective on High-Throughput Bioanalysis to Support In Vitro Assays in Early Drug Discovery	6
Quantitative polymerase chain reaction in the bioanalytical laboratory and technical and scientific considerations for nonclinical and clinical assay characterization, validation and sample analysis	6
Greener Bioanalytical Sample Preparation. What is Next?	6
Determination of aloesone in rat plasma by LC–MS/MS spectrometry and its application in a pharmacokinetic study	6
Comparison of Requirements for Clinical Study of SARS-CoV-2 Antigen Test Kits in China, the USA and Europe	6
Development and validation of an LC–MS/MS method for D- and L-2-hydroxyglutaric acid measurement in cerebrospinal fluid, urine and plasma: application to glioma	5
LC–MS/MS Methods for Direct Measurement of Sepiapterin and Tetrahydrobiopterin in Human Plasma and Clinical Applications	5
Quantification of a promising JNK inhibitor and nitrovasodilator IQ-1 and its major metabolite in rat plasma by LC–MS/MS	5

LC–MS Bioanalysis of Protein Biomarkers and Protein Therapeutics in Formalin-Fixed Paraffin-Embedded Tissue Specimens	5
Determination of Favipiravir in Human Plasma using Homogeneous Liquid–Liquid Microextraction followed by HPLC/UV	5
Development and validation of an ELISA method for quantification of the anti-HER3 antibody HMBD-001 in human serum	5
Fabry Disease Biomarkers in Patients Switched From Enzyme-Replacement Therapy to Migalastat Oral Chaperone Therapy	5
Effect of Chronopharmacology and Food on in Vivo Pharmacokinetic Profile of Mavacamten	5
Rapid Development of Analytical Methods for Evaluating Pandemic Vaccines: A Covid-19 Perspective	5
Development of LC–MS/MS Method for Cyanoenone Triterpenoid Determination to Support CNS Tissue Distribution Study	5
Prediction of frozen virus stability based on degradation mechanisms, real-time data and modeling	5
Critical reagent considerations for immunogenicity assay development for bispecific biotherapeutic candidates	5
Comparative pharmacokinetic study of Anisodamine Hydrobromide tablets and injection in septic acute lung injury rats	5
Role of miRNA-21 in cancer and its application in electrochemical bioanalysis	5
Single-Analyte Biomarker Assays for Pharmacodynamic or Safety Assessment During Biotherapeutic Development	5
A Biomarker Assay Validation Approach Tailored to The Context of Use and Bioanalytical Platform	5
Detection of Streptococcus anginosus in fecal samples using PCR-CRISPR /Cas12a system	5
Validation of an HPLC Method for Estimation of Cefotaxime from Dried Blood Spot: Alternative to Plasma-Based PK Evaluation in Neonates	5
Insights and Future Trends in Bioanalysis: An Interview With Jing Tu	4
Artificial intelligence and blockchain in clinical trials: enhancing data governance efficiency, integrity, and transparency	4
Capillary Electrophoresis Mass Spectrometry for Metabolomics: Reflecting on the Next Steps	4
Development and validation of an antidrug antibody assay for TRK-950 using Melon™ gel and SPEAD pretreatment	4
Quantification of MDR-TB drug JBD0131 and its metabolite in plasma via UPLC-MS/MS: application in first-in-human study	4
Harmonization of Vaccine Ligand Binding Assays Validation	4
Expanding Assay Range to Accommodate a Monoclonal Antibody Therapeutic Quantification in Blood and Cerebrospinal Fluid	4
A Validated Method for the Determination of Hematocrit in Dried Blood Spots Using Image Analysis	4
A comprehensive LC–MS based study of factors influencing biotinylation of critical reagents	4
Cloud Solutions for GxP Laboratories: Considerations for Data Storage	4
Validation and Application of Hybridization Liquid Chromatography-Tandem Mass Spectrometry Methods for Quantitative Bioanalysis of Antisense Oligonucleotides	4
Thyroxine Biosensors: A Review on Progress and Challenges	4
BiSim Tool: a binding simulation tool to aid and simplify ligand-binding assay design and development	4
Validated HPLC Method for Ceftriaxone from Dried Blood Spots for Pharmacokinetic Studies and Therapeutic Drug Monitoring in Neonatal Population	4
Pharmacokinetics and apparent Michaelis constant for metabolite conversion of sorafenib in healthy and hepatocellular carcinoma-bearing rats	4
High-resolution mass spectrometry for glycoproteomics	4
Development of pseudotyped VSV-SARS-CoV-2 spike variants for the assessment of neutralizing antibodies	4
Development and validation of highly sensitive ligand binding assay to measure soluble DLL3 concentration in human serum	4
Assessing linearity of vaccine immunogenicity assays: application and link with clinical endpoints	4
Bioanalysis Rising Star Award 2023: announcing our finalists	4
Characterization of Murine Lymphocyte Activation and Exhaustion Markers by a 14-Color Flow Cytometry Panel	4
Utilizing Droplet Digital Polymerase Chain Reaction for siRNA Quantitation in Rodent Plasma and Tissue Via Stem-Loop Reverse Transcription	4
Simultaneous Quantification of Oxcarbazepine and Its Active Metabolite in Spiked Human Plasma Using Ultra Performance Liquid Chromatography–MS/MS	4
A Smartphone Digital Image Colorimetric Method Based on Nanoparticles for Determination of Lamotrigine	4
Novel assay format for total anti-adeno-associated virus antibody detection with low capsid consumption and built-in specificity control	4
Bioanalysis of tucatinib and metabolite, and a five-way cross-validation to support clinical pharmacokinetic analysis	4
2024 White Paper on Recent Issues in Bioanalysis: Three Way-Cross Validation; Urine Clinical Analysis; Automated Methods; Regulatory Queries on Plasma Protein Binding; Automated Biospecimen Management	4
Pitfalls in bioanalytical work with a Japanese CRO or sponsor: from a project risk management perspective	4
Advances in green sample preparation methods for bioanalytical laboratories focusing on drug analysis	3
High-Throughput MS for Intact Protein Analysis	3
High-sensitivity Quantification of Antisense Oligonucleotides for Pharmacokinetic Characterization	3
Integrating metering capabilities to increase the utility of self-collected, dried samples	3
Lessons Learned from Regulatory Submissions Involving Endogenous Therapeutic Analyte Bioanalysis	3
China's NMPA Perspective on the Clinical Performance of SARS-CoV-2 Antigen Test Reagents	3
Comparison of Liquid–Liquid Extraction, Microextraction and Ultrafiltration for Measuring Free Concentrations of Testosterone and Phenytoin	3
Thalidomide Measurement in Plasma and Dried Plasma Spot by SPE Combined with UHPLC-MS/MS for Therapeutic Drug Monitoring	3
Singlicate analysis in ADA assays: comparing assay performance in duplicate and singlicate formats	3
Multi-residue analysis method based on QuEChERS followed by ultra-high performance liquid chromatography coupled with diode-array detector for pesticides in human serum and breast milk	3
Nitrosamine Impurities: from Raw Materials to Final Drug Product	3
Development of a validated novel bead extraction method for the detection of anti-PEG antibodies in human serum	3
Moving into the cloud: a summary from a European Bioanalysis forum workshop on introducing cloud applications in bioanalytical laboratories	3
Pharmacokinetics and Toxicity Considerations for Antibody–drug Conjugates: An Overview	3
LC–MS/MS Bioanalytical Method for Quantification of Binimetinib and Venetoclax, and their Pharmacokinetic Interaction	3
Analytical Considerations to Support Expeditious Formulation Development of Vaccines	3
With Great Power Comes Great Responsibility: High-Dimensional Spectral Flow Cytometry to Support Clinical Trials	3
A Bioanalytical Screening Method for Enterococcus faecalis RNPP-type Quorum Sensing Peptides in Murine Feces	3
Testing in the Workplace: Finding a Path Through a Pandemic	3
Blood Cell Quantification on Dry Blood Samples: Toward Patient-Centric Complete Blood Counts	3
Accelerating isotope dilution LC-MS-based desmosine quantification for estimating elastin turnover	3
Welcome to Volume 14 of Bioanalysis	3
Large Molecule Bioanalysis by LC–MS: Beyond Simply Quantifying	3
Re-thinking the current paradigm for clinical immunogenicity assessment: an update from the discussion in the European Bioanalysis Forum	3
Simultaneous estimation of donepezil and quercetin using ultra high performance liquid chromatography: pharmaceutical and pharmacokinetic applications in Alzheimer’s disease	3
Enantioselective electrochemical detection of a L-and D-serine at polyvinylpyrrolidone-modified platinum electrode	3
Development and Validation of Reversed-Phase-HPLC Method for Simultaneous Quantification of Fulvestrant and Disulfiram in Liposomes	3
LC–MS/MS method for quantification of raspberry ketone in rat plasma: application to preclinical pharmacokinetic studies	3
2023 White Paper on Recent Issues in Bioanalysis: Deuterated Drugs; LNP; Tumor/FFPE Biopsy; Targeted Proteomics; Small Molecule Covalent Inhibitors; Chiral Bioanalysis; Remote Regulatory Assessments;	3
Feasibility of using PALSAR technology as a signal amplifier for antibody bridging assay	3
Direct bioanalysis or indirect calculation of target engagement and free drug exposure: do we apply double standards?	3
Volumetric Absorptive Microsampling: Its Use in Covid-19 Research and Testing	3
Volumetric absorptive microsampling–LC–MS/MS assays for quantitation of giredestrant in dried human whole blood	3
LC-MS/MS Methods to quantify HCP002 in Human Plasma and Urine: Applications in a Pharmacokinetic Study	3
Free serum concentrations of antibiotics determined by ultrafiltration: extensive evaluation of experimental variables	3
Quantifying skin permeation of a novel metformin lotion using modified hydrophilic interaction liquid chromatography	3
Research progress of N -nitrosamine detection methods: a review	3

Green HPLC method for determination of paracetamol and ibuprofen in human plasma: applications to pharmacokinetics	3
A Validated Capillary Microsampling Liquid Chromatography–Tandem Mass Spectrometry Method for Quantification of Antisense Oligonucleotides in Mouse Serum	3
Measuring HSD17β13 protein turnover in mouse liver with D 2 O metabolic labeling and hybrid LC-MS	3
2024 White paper on recent issues in bioanalysis: Impact of LDT in US and IVDR in EU; AI/ML for High Parameter Flow Cytometry; The rise of Olink Technology; CDx for AAV Gene Therapies; Integrative Bio	3