Bioanalysis

Article	Citations
Meet the Editorial Board – An Interview with Min Meng and Transitions from Small Regional Labs to Global CRO	41
Biomonitoring of Arsenic, Lead, Manganese and Mercury in Hair from a Presumably Exposed Uruguayan Child Population	30
Biomarker Context-Of-Use: How Organizational Design Can Impact the Implementation of the Appropriate Biomarker Assay Strategy	29
Volumetric Absorptive Microsampling as An Effective Microsampling Technique for LC–MS/MS Bioanalysis of Biomarkers in Drug Discovery	26
Bioanalysis by LC-MS/MS and Preclinical Pharmacokinetic Interaction Study of Ribociclib and Oleanolic Acid	25
Adopting ambient ionization mass spectrometry into bioanalytical laboratories	22
Peripheral blood mononuclear cells isolation from mouse and rabbit blood to quantify active nucleotide and define brincidofovir dose for smallpox	21
Patient centric blood sampling and analysis for diagnostics and laboratory medicine	18
The complexities of oligonucleotide therapeutics: analytical challenges and opportunities within early drug discovery	16
Signal-to-noise Ratio to Assess Magnitude, Kinetics and Impact on Pharmacokinetics of the Immune Response to an Adalimumab Biosimilar	14
MS-DIAL pre-processing for mining schistosomiasis metabolites in urine samples from the Okavango Delta of Botswana from a GC-MS dataset	14
Strategy and Validation of a Nonclinical Generic Plug-and-Play Antidrug Antibody Method for Human Monoclonal Antibody Biotherapeutics	13
Patient-centric clinical trials: collaboration and innovation in bioanalytical and clinical operations	13
Uncovering the Green Frontier: Harnessing Deep Eutectic Solvents for Sustainable Bioanalysis	13
Selective IgM digestion improves anti-AAV IgG detection in the immune complex assay format	12
Determination of carbamazepine in fingerprints: a feasibility study to evaluate adherence in epilepsy patients	12
Recent advances in gold nanoparticle-based colorimetric aptasensors for chemical and biological analyses	12
Iron oxide nanozymes as versatile analytical tools: an overview of their application as detection technique	11
Whole blood stability in bioanalytical method validation: updated recommendations from the European Bioanalysis Forum	11
Determination of IQZ23 in Rat Plasma using LC-MS/MS: Consideration for Matrix Effect and Internal Standard Interference	11
HPPA as assay substrate for improved capturing of sample variability during cut point analyses in immunogenicity testing	11
A clever evaluation of the antidiabetic medications linagliptin and empagliflozin in bulk and spiked urine samples	11
Refined ADA testing strategy to overcome sRANKL interference in denosumab/FKS518 immunogenicity assessment	11
A comparison of branched DNA and reverse transcriptase quantitative polymerase chain reaction methodologies for quantitation of lipid nanoparticle encapsulated mRNA	10
Diversity and Inclusion in the Bioanalytical Industry: An Interview with Anahita Keyhani	10

Bioanalysis Rising Star Award 2024: interviews with the finalists	10
Ligand-binding assays vs chromatographic platforms for oligonucleotide quantification	9
Perspectives on a Flexible Strategy for the Management of Nonregulated Bioanalysis	9
Accelerating the discovery of MET inhibitors powered by high-throughput hit identification	9
Significant matrix effect in fludarabine quantification in plasma: implications for CAR-T cell therapy monitoring	9
Simultaneous Measurement of Mouse and Human Albumin in Chimeric Mice with Humanized Livers	9
A novel LC-MS/MS method for simultaneous estimation of chlordiazepoxide and clidinium in human plasma and its application to pharmacokinetic assessment	9
Comparison of Assay Formats Used for the Detection of Pre-Existing Anti-Drug Antibodies Against Monoclonal Antibodies	9
An LC–MS/MS Method for Simultaneous Determination of LB-100 and Its Active Metabolite, Endothall, in Human Plasma	9
The investigation of connection between anticoagulant therapy and vitamin K homologues in human determined by LC–MS/MS	9
Special consideration: commentary on the 2025 FDA Bioanalytical Method Validation for Biomarkers	9
Development of a fit-for-purpose semi-homogeneous competitive ELISA for total PEG quantitation in a PEGylated molecule	9
Bioanalysis of free antisense oligonucleotide payload from antibody–oligonucleotide conjugate by hybridization LC-MS/MS	8
Determination of meropenem in capillary plasma microsamples using LC–MS/MS	8
Considerations in Designing and Implementing a Bioanalytical Contract Research Organization Key Performance Indicator System	8
Correction	8
Validation of an LC–MS/MS method for the determination of sotorasib, a KRAS G12C inhibitor, in human plasma	8
Highlights of the 15th Japan Bioanalysis Forum Symposium	8
Method development for the quantification of lead levels in whole blood sampled on Mitra ® with VAMS ® tips by inductively coupled	8
Development and Validation of qPCR Methods for Nucleic Acid Biomarkers as a Drug Development Tool: Points to Consider	8
Transforming drug discovery: the impact of AI and molecular simulation on R&D efficiency	8
Inception and Development of a LC–MS/MS Assay for the Multiplexed Quantitation of Nine Human Drug Transporter Biomarkers	8
Western Blotting: Evolution of an Old Analytical Method To a New Quantitative Tool for Biomarker Measurements	8
Highlights of the 13th Japan Bioanalysis Forum Symposium	8
Determination of Amphetamines, Opioids, Cocaine Metabolites and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in Urine Using Biocompatible Solid-Phase Microextraction and Ultra-Performance LC–MS/MS	7
High Ionic Strength Dissociation Assay Reduces Dimeric Target Interference in Immunogenicity Testing	7
Molecularly Imprinted Electrochemical Biosensor for Thrombin Detection by Comparing Different Monomers	7
Critical Reagent Inventory Management System and Web Portal Specifically Optimized for Supporting External Clients	7
Novel Isoelectric Target Depletion (ITaD) Protocol Reduces the Need for Specific Reagents for Immunogenicity Testing	7
Development of an LC-MS/MS assay to analyze a lipid-conjugated siRNA by solid phase extraction (SPE) in mouse plasma and tissue using a stable isotope labeled internal standard (SILIS)	7
Validation of UV–Vis spectrophotometric colorimetric methods for Rifampicin quantification in PBS & biological matrices	7
Nucleic acid nanorobot assay for accurate and simplified ASO quantification in mouse plasma	7
An interview with Bioanalysis : speaking with the 2025 international reid bioanalytical forum bursary award winners	6
A Sensitive, Robust and High-Throughput Isotope Dilution LC–MS/MS Method for Quantifying Three Folate Forms in Serum	6
Revolutionizing depression diagnosis: earwax analysis for cortisol and beyond	6
An Eco-Friendly Ultra-Performance Liquid Chromatography–Mass Spectrometry Method for Quantification of Rivaroxaban and Ticagrelor in Rat Plasma: Grapefruit Interactions	6
Rethinking validation paradigms for qPCR and dPCR assays in bioanalysis	6
Upfront Acid Treatment with Low Final pH: The Development and Testing of a Novel Method to Improve Drug Tolerance in Antidrug Antibody Assays	6
Determination of aloesone in rat plasma by LC–MS/MS spectrometry and its application in a pharmacokinetic study	6
Beyond contracts: principles for Pharma–CRO collaboration from the European Bioanalysis Forum	6
Greener Bioanalytical Sample Preparation. What is Next?	6
Development and validation of bioanalytical methods to support clinical study of disitamab vedotin	6
Ocular Bioanalysis of Moxifloxacin and Ketorolac Tromethamine in Rabbit Lacrimal Matrix Using Liquid Chromatography–Tandem Mass Spectrometry	6
Internal standard variability: root cause investigation, parallelism for evaluating trackability and practical considerations	6
Comparison of Requirements for Clinical Study of SARS-CoV-2 Antigen Test Kits in China, the USA and Europe	6
HPLC Method for Simultaneous Estimation of Paclitaxel and Baicalein: Pharmaceutical and Pharmacokinetic Applications	6
Quantitative polymerase chain reaction in the bioanalytical laboratory and technical and scientific considerations for nonclinical and clinical assay characterization, validation and sample analysis	6
Quantitation of BCAA and BCKA in plasma and patient-centric dried blood microsamples in a clinical setting	6
Comparison of multiple bioanalytical assay platforms for the quantitation of siRNA therapeutics	5
Comparative pharmacokinetic study of Anisodamine Hydrobromide tablets and injection in septic acute lung injury rats	5

LC–MS Bioanalysis of Protein Biomarkers and Protein Therapeutics in Formalin-Fixed Paraffin-Embedded Tissue Specimens	5
Single-Analyte Biomarker Assays for Pharmacodynamic or Safety Assessment During Biotherapeutic Development	5
When is a sample a urine sample? Markers for urine sample authenticity assessment in sports drug testing	5
Development of LC–MS/MS Method for Cyanoenone Triterpenoid Determination to Support CNS Tissue Distribution Study	5
Perspective on High-Throughput Bioanalysis to Support In Vitro Assays in Early Drug Discovery	5
Critical reagent considerations for immunogenicity assay development for bispecific biotherapeutic candidates	5
Detection of Streptococcus anginosus in fecal samples using PCR-CRISPR /Cas12a system	5
Prediction of frozen virus stability based on degradation mechanisms, real-time data and modeling	5
LC-MS/MS method for co-estimation of doxorubicin and piperine: formulation development and pharmacokinetic studies	5
Effect of Chronopharmacology and Food on in Vivo Pharmacokinetic Profile of Mavacamten	5
DoE-assisted HPLC method development and validation of enzalutamide and repaglinide in rat plasma	5
Development and validation of an LC–MS/MS method for D- and L-2-hydroxyglutaric acid measurement in cerebrospinal fluid, urine and plasma: application to glioma	5
Role of miRNA-21 in cancer and its application in electrochemical bioanalysis	5
The acute oral toxicity and pharmacokinetic determination of a novel chloroquinoline hybrid molecule by LC-MS/MS	5
Quantification of a promising JNK inhibitor and nitrovasodilator IQ-1 and its major metabolite in rat plasma by LC–MS/MS	5
Validation and Application of Hybridization Liquid Chromatography-Tandem Mass Spectrometry Methods for Quantitative Bioanalysis of Antisense Oligonucleotides	4
Development and validation of an antidrug antibody assay for TRK-950 using Melon™ gel and SPEAD pretreatment	4
Capillary Electrophoresis Mass Spectrometry for Metabolomics: Reflecting on the Next Steps	4
Thyroxine Biosensors: A Review on Progress and Challenges	4
A Smartphone Digital Image Colorimetric Method Based on Nanoparticles for Determination of Lamotrigine	4
Bioanalysis of tucatinib and metabolite, and a five-way cross-validation to support clinical pharmacokinetic analysis	4
Novel assay format for total anti-adeno-associated virus antibody detection with low capsid consumption and built-in specificity control	4
Fabry Disease Biomarkers in Patients Switched From Enzyme-Replacement Therapy to Migalastat Oral Chaperone Therapy	4
Development of pseudotyped VSV-SARS-CoV-2 spike variants for the assessment of neutralizing antibodies	4
A Validated Method for the Determination of Hematocrit in Dried Blood Spots Using Image Analysis	4
BiSim Tool: a binding simulation tool to aid and simplify ligand-binding assay design and development	4
Insights and Future Trends in Bioanalysis: An Interview With Jing Tu	4
High-resolution mass spectrometry for glycoproteomics	4
Development and validation of highly sensitive ligand binding assay to measure soluble DLL3 concentration in human serum	4
Assessing linearity of vaccine immunogenicity assays: application and link with clinical endpoints	4
Bioanalytical tandem mass spectrometry method for cinacalcet in human plasma: green assessment with advanced metrics	4
LC–MS/MS Methods for Direct Measurement of Sepiapterin and Tetrahydrobiopterin in Human Plasma and Clinical Applications	4
Development and validation of an ELISA method for quantification of the anti-HER3 antibody HMBD-001 in human serum	4
2024 White Paper on Recent Issues in Bioanalysis: Three Way-Cross Validation; Urine Clinical Analysis; Automated Methods; Regulatory Queries on Plasma Protein Binding; Automated Biospecimen Management	4
Characterization of Murine Lymphocyte Activation and Exhaustion Markers by a 14-Color Flow Cytometry Panel	4
Expanding Assay Range to Accommodate a Monoclonal Antibody Therapeutic Quantification in Blood and Cerebrospinal Fluid	4
A comprehensive LC–MS based study of factors influencing biotinylation of critical reagents	4
Pharmacokinetics and apparent Michaelis constant for metabolite conversion of sorafenib in healthy and hepatocellular carcinoma-bearing rats	4
Harmonization of Vaccine Ligand Binding Assays Validation	4
Pitfalls in bioanalytical work with a Japanese CRO or sponsor: from a project risk management perspective	4
Determination of Favipiravir in Human Plasma using Homogeneous Liquid–Liquid Microextraction followed by HPLC/UV	4
A Biomarker Assay Validation Approach Tailored to The Context of Use and Bioanalytical Platform	4
Integrating metering capabilities to increase the utility of self-collected, dried samples	3
Effect of delayed blood centrifugation on cytokine quantitation in serum and plasma	3
LC–MS/MS method for quantification of raspberry ketone in rat plasma: application to preclinical pharmacokinetic studies	3
Direct bioanalysis or indirect calculation of target engagement and free drug exposure: do we apply double standards?	3
2023 White Paper on Recent Issues in Bioanalysis: Deuterated Drugs; LNP; Tumor/FFPE Biopsy; Targeted Proteomics; Small Molecule Covalent Inhibitors; Chiral Bioanalysis; Remote Regulatory Assessments;	3
Free serum concentrations of antibiotics determined by ultrafiltration: extensive evaluation of experimental variables	3
Singlicate analysis in ADA assays: comparing assay performance in duplicate and singlicate formats	3
Multi-residue analysis method based on QuEChERS followed by ultra-high performance liquid chromatography coupled with diode-array detector for pesticides in human serum and breast milk	3
Feasibility of using PALSAR technology as a signal amplifier for antibody bridging assay	3
Development of a validated novel bead extraction method for the detection of anti-PEG antibodies in human serum	3
Research progress of N -nitrosamine detection methods: a review	3
Analytical Considerations to Support Expeditious Formulation Development of Vaccines	3
A Bioanalytical Screening Method for Enterococcus faecalis RNPP-type Quorum Sensing Peptides in Murine Feces	3
Development of a UPLC-MS/MS method for simultaneous quantification of 7 bile acids in feces: application to UC mice	3
Artificial intelligence and blockchain in clinical trials: enhancing data governance efficiency, integrity, and transparency	3
Simultaneous estimation of donepezil and quercetin using ultra high performance liquid chromatography: pharmaceutical and pharmacokinetic applications in Alzheimer’s disease	3
Large Molecule Bioanalysis by LC–MS: Beyond Simply Quantifying	3
Unique challenges required reassessment and alterations to critical reagents to rescue a neutralizing antibody assay	3
Single-Day Protein LC–MS Bioanalysis: Can Next-Generation Trypsins Cut It?	3
China's NMPA Perspective on the Clinical Performance of SARS-CoV-2 Antigen Test Reagents	3
Two decades of immunocapture liquid chromatography tandem mass spectrometry for pharmaceutical discovery and development: reflections and recommendations for optimal deployment	3
Thalidomide Measurement in Plasma and Dried Plasma Spot by SPE Combined with UHPLC-MS/MS for Therapeutic Drug Monitoring	3
Advances in green sample preparation methods for bioanalytical laboratories focusing on drug analysis	3
Validated HPLC Method for Ceftriaxone from Dried Blood Spots for Pharmacokinetic Studies and Therapeutic Drug Monitoring in Neonatal Population	3
Lessons Learned from Regulatory Submissions Involving Endogenous Therapeutic Analyte Bioanalysis	3
Moving into the cloud: a summary from a European Bioanalysis forum workshop on introducing cloud applications in bioanalytical laboratories	3
High-Throughput MS for Intact Protein Analysis	3
Re-thinking the current paradigm for clinical immunogenicity assessment: an update from the discussion in the European Bioanalysis Forum	3
A Validated Capillary Microsampling Liquid Chromatography–Tandem Mass Spectrometry Method for Quantification of Antisense Oligonucleotides in Mouse Serum	3
LC-MS/MS Methods to quantify HCP002 in Human Plasma and Urine: Applications in a Pharmacokinetic Study	3
Bioanalysis Rising Star Award 2023: announcing our finalists	3
Comparison of Liquid–Liquid Extraction, Microextraction and Ultrafiltration for Measuring Free Concentrations of Testosterone and Phenytoin	3
Utilizing Droplet Digital Polymerase Chain Reaction for siRNA Quantitation in Rodent Plasma and Tissue Via Stem-Loop Reverse Transcription	3
Pharmacokinetics and Toxicity Considerations for Antibody–drug Conjugates: An Overview	3
2024 White paper on recent issues in bioanalysis: Impact of LDT in US and IVDR in EU; AI/ML for High Parameter Flow Cytometry; The rise of Olink Technology; CDx for AAV Gene Therapies; Integrative Bio	3
Conference Report from the European Bioanalysis Forum Workshop: toward harmonized implementation of the ICH M10 guideline	3
Pertinence of microsampling in various nonclinical and clinical studies: the ICH perspective	3
Volumetric absorptive microsampling–LC–MS/MS assays for quantitation of giredestrant in dried human whole blood	3

High-sensitivity Quantification of Antisense Oligonucleotides for Pharmacokinetic Characterization	3
Blood Cell Quantification on Dry Blood Samples: Toward Patient-Centric Complete Blood Counts	3
Covalent organic frameworks: spotlight on applications in the pharmaceutical arena	3
Mass spectrometry for clinical bioanalysis without chromatographic separation: bioequivalence for bupropion and its metabolites	3
Accelerating isotope dilution LC-MS-based desmosine quantification for estimating elastin turnover	3
Green HPLC method for determination of paracetamol and ibuprofen in human plasma: applications to pharmacokinetics	3
Method development and validation for simultaneous analysis of four bile acids as CYP3A drug–drug interaction biomarkers	3
Quantifying skin permeation of a novel metformin lotion using modified hydrophilic interaction liquid chromatography	3
Measuring HSD17β13 protein turnover in mouse liver with D 2 O metabolic labeling and hybrid LC-MS	3
Simultaneous quantitation of tigecycline, meropenem, polymyxin B in plasma, and protein-binding analysis in HSCT patients	3
Quantification of MDR-TB drug JBD0131 and its metabolite in plasma via UPLC-MS/MS: application in first-in-human study	3
Development and Validation of Reversed-Phase-HPLC Method for Simultaneous Quantification of Fulvestrant and Disulfiram in Liposomes	3
Enantioselective electrochemical detection of a L-and D-serine at polyvinylpyrrolidone-modified platinum electrode	3
Evaluation of hemaPEN ® sampling device for measurement of cocaine and metabolites in capillary blood by LC-MS/MS	3