OOIR: Observatory of International Research

Papers

(The H4-Index of Stem Cell Research & Therapy is 57. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-04-01 to 2025-04-01.)

Article	Citations
Cardio-renal effect of dapagliflozin and dapagliflozin- saxagliptin combination on CD34 + ve hematopoietic stem cells (HSCs) and podocyte specific markers in type 2 diabetes (T2DM) subjects: a randomi	216
Migrasomes derived from human umbilical cord mesenchymal stem cells: a new therapeutic agent for ovalbumin-induced asthma in mice	193
Retraction Note: Mesenchymal stem cell-derived exosomes exert ameliorative effects in type 2 diabetes by improving hepatic glucose and lipid metabolism via enhancing autophagy	172
Retraction Note: Mesenchymal stem cell-derived exosome miR-542-3p suppresses inflammation and prevents cerebral infarction	120
Inhibition of circALPK2 enhances proliferation and therapeutic potential of human pluripotent stem cell-derived cardiomyocytes in myocardial infarction	118
Thrombin-preconditioned mesenchymal stromal cell-derived extracellular vesicles attenuate experimental necrotizing enterocolitis	114
Dedifferentiated fat cells-derived exosomes (DFATs-Exos) loaded in GelMA accelerated diabetic wound healing through Wnt/β-catenin pathway	113
The promise of mesenchymal stromal/stem cells in erectile dysfunction treatment: a review of current insights and future directions	112
Mesenchymal stem cells overexpressing neuropeptide S promote the recovery of rats with spinal cord injury by activating the PI3K/AKT/GSK3β signaling pathway	112
Huc-MSCs-derived exosomes alleviate non-alcoholic steatohepatitis by regulating macrophages polarization through miR-24-3p/STING axis	109
Gain of 20q11.21 in human pluripotent stem cells enhances differentiation to retinal pigment epithelium	108
Effects of intra-articular applied rat BMSCs expressing alpha-calcitonin gene-related peptide or substance P on osteoarthritis pathogenesis in a murine surgical osteoarthritis model	105
Purine metabolism in bone marrow microenvironment inhibits hematopoietic stem cell differentiation under microgravity	101
Single-cell transcriptomics of clinical grade adipose-derived regenerative cells reveals consistency between donors independent of gender and BMI	98
Effects and mechanisms of breastmilk stem cells in the treatment of white matter injury in newborn rats	95
Hormone correction of dysfunctional metabolic gene expression in stem cell-derived liver tissue	93
Neuroblasts migration under control of reactive astrocyte-derived BDNF: a promising therapy in late neurogenesis after traumatic brain injury	92
Hepatic progenitor cells reprogrammed from mouse fibroblasts repopulate hepatocytes in Wilson’s disease mice	92
Engineered basic fibroblast growth factor-overexpressing human umbilical cord-derived mesenchymal stem cells improve the proliferation and neuronal differentiation of endogenous neural stem cells and	87
Human intestinal organoid-derived PDGFRα + mesenchymal stroma enables proliferation and maintenance of LGR4 + epithelial stem cells	84
Dual inhibition of P38 MAPK and JNK pathways preserves stemness markers and alleviates premature activation of muscle stem cells during isolation	82
Mesenchymal stromal cells: promising treatment for liver cirrhosis	82
Advancements in cell-based therapies for thermal burn wounds: a comprehensive systematic review of clinical trials outcomes	80
Ultrasound cavitation: a reliable non-enzymatic method for adipose-derived mesenchymal stem cell (ADSC) isolation	79
Retraction Note: Ang II-AT2R increases mesenchymal stem cell migration by signaling through the FAK and RhoA/Cdc42 pathways in vitro	74

Forward programming of hPSCs to neutrophils using chemically defined media	74
Targeting ferroptosis: opportunities and challenges of mesenchymal stem cell therapy for type 1 diabetes mellitus	74
Mesenchymal stem cell-mediated adipogenic transformation: a key driver of oral squamous cell carcinoma progression	73
Mesenchymal stromal cell exosomes for drug delivery of prostate cancer treatments: a review	72
Magnesium ions regulate the Warburg effect to promote the differentiation of enteric neural crest cells into neurons	72
Dental pulp stem cell-derived intracellular vesicles prevent orthodontic relapse by inhibiting PI3K/Akt/NF-κB-mediated osteoclast activity	72
Inter-center comparison of good manufacturing practices-compliant stromal vascular fraction and proposal for release acceptance criteria: a review of 364 productions	71
Acceptability of neural stem cell therapy for cerebral palsy: survey of the Australian cerebral palsy community	71
PINK1 deficiency impairs osteoblast differentiation through aberrant mitochondrial homeostasis	69
Removing the stumbling block of exosome applications in clinical and translational medicine: expand production and improve accuracy	68
Insight into microRNAs’ involvement in hematopoiesis: current standing point of findings	67
Cigarette smoke impairs the hematopoietic supportive property of mesenchymal stem cells via the production of reactive oxygen species and NLRP3 activation	67
Exogenous melatonin ameliorates steroid-induced osteonecrosis of the femoral head by modulating ferroptosis through GDF15-mediated signaling	67
Hypoxia-preconditioned WJ-MSC spheroid-derived exosomes delivering miR-210 for renal cell restoration in hypoxia-reoxygenation injury	66
Therapeutic potential of exosomal lncRNAs derived from stem cells in wound healing: focusing on mesenchymal stem cells	66
Efficacy of human umbilical cord mesenchymal stem cell in the treatment of neuromyelitis optica spectrum disorders: an animal study	65
FBF1 maintains stem cell-like properties in breast cancer via PI3K/AKT/SOX2 axis	64
Biomimetic nerve guidance conduit containing engineered exosomes of adipose-derived stem cells promotes peripheral nerve regeneration	63
Chronic obstructive pulmonary disease and asthma: mesenchymal stem cells and their extracellular vesicles as potential therapeutic tools	63
Regulation of the integrin αVβ3- actin filaments axis in early osteogenesis of human fibroblasts under cyclic tensile stress	62
Single-cell transcriptomics reveals the cell fate transitions of human dopaminergic progenitors derived from hESCs	62
Mid- to long-term efficacy and safety of stem cell therapy for acute myocardial infarction: a systematic review and meta-analysis	61
Application of Wharton jelly-derived mesenchymal stem cells in patients with pulmonary fibrosis	61
Electrical stimulation affects the differentiation of transplanted regionally specific human spinal neural progenitor cells (sNPCs) after chronic spinal cord injury	61
Mesenchymal stem/stromal cell therapy for COVID-19 pneumonia: potential mechanisms, current clinical evidence, and future perspectives	60
Insufficient S-adenosylhomocysteine hydrolase compromises the beneficial effect of diabetic BMSCs on diabetic cardiomyopathy	60
Chronic inflammation-induced senescence impairs immunomodulatory properties of synovial fluid mesenchymal stem cells in rheumatoid arthritis	59
MiR-34a-HK1 signal axis retards bone marrow mesenchymal stem cell senescence via ameliorating glycolytic metabolism	58
Kupffer cells abrogate homing and repopulation of allogeneic hepatic progenitors in injured liver site	58
Treatment of COVID-19-associated ARDS with umbilical cord-derived mesenchymal stromal cells in the STROMA-CoV-2 multicenter randomized double-blind trial: long-term safety, respiratory function, and q	58
Valproic acid promotes the in vitro differentiation of human pluripotent stem cells into spermatogonial stem cell-like cells	58
Fasudil and viscosity of gelatin promote hepatic differentiation by regulating organelles in human umbilical cord matrix-mesenchymal stem cells	57