OOIR: Observatory of International Research

Papers

(The TQCC of Biofabrication is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-04-01 to 2024-04-01.)

Article	Citations
Engineering bioinks for 3D bioprinting	117
3D printed oxidized alginate-gelatin bioink provides guidance for C2C12 muscle precursor cell orientation and differentiation via shear stress during bioprinting	82
Improving alginate printability for biofabrication: establishment of a universal and homogeneous pre-crosslinking technique	80
Printability in extrusion bioprinting	75
Nanoclay-based 3D printed scaffolds promote vascular ingrowth ex vivo and generate bone mineral tissue in vitro and in vivo	71
3D Printing of large-scale and highly porous biodegradable tissue engineering scaffolds from poly(trimethylene-carbonate) using two-photon-polymerization	57
Droplet-based microfluidics in biomedical applications	51
Combinations of photoinitiator and UV absorber for cell-based digital light processing (DLP) bioprinting	50
Cell spheroids as a versatile research platform: formation mechanisms, high throughput production, characterization and applications	50
Biofabrication of endothelial cell, dermal fibroblast, and multilayered keratinocyte layers for skin tissue engineering	50
GelMA/bioactive silica nanocomposite bioinks for stem cell osteogenic differentiation	49
Modeling the printability of photocuring and strength adjustable hydrogel bioink during projection-based 3D bioprinting	48
Dual drug delivery system based on pH-sensitive silk fibroin/alginate nanoparticles entrapped in PNIPAM hydrogel for treating severe infected burn wound	47
A novel tumor-immune microenvironment (TIME)-on-Chip mimics three dimensional neutrophil-tumor dynamics and neutrophil extracellular traps (NETs)-mediated collective tumor invasion	47
Recent advances in 3D bioprinting of musculoskeletal tissues	46
3D printed titanium scaffolds with homogeneous diamond-like structures mimicking that of the osteocyte microenvironment and its bone regeneration study	45
Dynamic hyaluronic acid hydrogel with covalent linked gelatin as an anti-oxidative bioink for cartilage tissue engineering	44
Sound-induced morphogenesis of multicellular systems for rapid orchestration of vascular networks	44
3D cell-printing of tendon-bone interface using tissue-derived extracellular matrix bioinks for chronic rotator cuff repair	44
Cartilage tissue engineering by extrusion bioprinting utilizing porous hyaluronic acid microgel bioinks	43
Using chaotic advection for facile high-throughput fabrication of ordered multilayer micro- and nanostructures: continuous chaotic printing	43
Self-crosslinking hyaluronic acid–carboxymethylcellulose hydrogel enhances multilayered 3D-printed construct shape integrity and mechanical stability for soft tissue engineering	43
Multi-material digital light processing bioprinting of hydrogel-based microfluidic chips	42
Multimaterial bioprinting and combination of processing techniques towards the fabrication of biomimetic tissues and organs	42
Dynamic peptide-folding mediated biofunctionalization and modulation of hydrogels for 4D bioprinting	41

High throughput direct 3D bioprinting in multiwell plates	40
Bio-3D printing iPSC-derived human chondrocytes for articular cartilage regeneration	38
Recent advancements in the bioprinting of vascular grafts	38
4D Biofabrication of fibrous artificial nerve graft for neuron regeneration	37
A targeted rheological bioink development guideline and its systematic correlation with printing behavior	36
Fabrication of MSC-laden composites of hyaluronic acid hydrogels reinforced with MEW scaffolds for cartilage repair	35
On-chip high-definition bioprinting of microvascular structures	35
A biofabrication method to align cells within bioprinted photocrosslinkable and cell-degradable hydrogel constructs via embedded fibers	35
Bioprinting of an osteocyte network for biomimetic mineralization	35
Green electrospinning for biomaterials and biofabrication	34
Alginate–gelatin–Matrigel hydrogels enable the development and multigenerational passaging of patient-derived 3D bioprinted cancer spheroid models	34
Aspiration-assisted bioprinting of co-cultured osteogenic spheroids for bone tissue engineering	34
Bio-instructive hydrogel expands the paracrine potency of mesenchymal stem cells	33
Double network laminarin-boronic/alginate dynamic bioink for 3D bioprinting cell-laden constructs	33
A digital light processing 3D printed magnetic bioreactor system using silk magnetic bioink	33
Engineering microvasculature by 3D bioprinting of prevascularized spheroids in photo-crosslinkable gelatin	33
4D bioprintable self-healing hydrogel with shape memory and cryopreserving properties	32
Recapitulating monocyte extravasation to the synovium in an organotypic microfluidic model of the articular joint	31
Combining electrospinning with hot drawing process to fabricate high performance poly (L-lactic acid) nanofiber yarns for advanced nanostructured bio-textiles	31
Vascularized adipocyte organoid model using isolated human microvessel fragments	31
3D bioprinted, vascularized neuroblastoma tumor environment in fluidic chip devices for precision medicine drug testing	29
Improved accuracy and precision of bioprinting through progressive cavity pump-controlled extrusion	28
Enabling peristalsis of human colon tumor organoids on microfluidic chips	28
Magnetic molding of tumor spheroids: emerging model for cancer screening	27
Fabrication of microvascular constructs using high resolution electrohydrodynamic inkjet printing	27
Towards engineering heart tissues from bioprinted cardiac spheroids	27
3D bioprinting of molecularly engineered PEG-based hydrogels utilizing gelatin fragments	27
High throughput microfluidic system with multiple oxygen levels for the study of hypoxia in tumor spheroids	27
Mimicking tumor microenvironment by 3D bioprinting: 3D cancer modeling	26
Biomimetic and mechanically supportive 3D printed scaffolds for cartilage and osteochondral tissue engineering using photopolymers and digital light processing	26
Bioengineered in vitro 3D model of myotonic dystrophy type 1 human skeletal muscle	25
Bioactive Sr²⁺/Fe³⁺ co-substituted hydroxyapatite in cryogenically 3D printed porous scaffolds for bone tissue engineering	25
Enhanced vascularization and de novo tissue formation in hydrogels made of engineered RGD-tagged spider silk proteins in the arteriovenous loop model	25
Aspiration-assisted freeform bioprinting of mesenchymal stem cell spheroids within alginate microgels	25
Decellularized kidney extracellular matrix bioinks recapitulate renal 3D microenvironment in vitro	25
Bioink with cartilage-derived extracellular matrix microfibers enables spatial control of vascular capillary formation in bioprinted constructs	25
Tunable metacrylated hyaluronic acid-based hybrid bioinks for stereolithography 3D bioprinting	24
Engineered assistive materials for 3D bioprinting: support baths and sacrificial inks	23
Simultaneous 2D and 3D cell culture array for multicellular geometry, drug discovery and tumor microenvironment reconstruction	23
Neural stem cell delivery using brain-derived tissue-specific bioink for recovering from traumatic brain injury	23
FRESH 3D bioprinting a contractile heart tube using human stem cell-derived cardiomyocytes	23
Scalable fabrication of renal spheroids and nephron-like tubules by bioprinting and controlled self-assembly of epithelial cells	23
Next generation human brain models: engineered flat brain organoids featuring gyrification	22
An injectable bioink with rapid prototyping in the air and in-situ mild polymerization for 3D bioprinting	22
Scaffold microarchitecture regulates angiogenesis and the regeneration of large bone defects	22
BoneMA—synthesis and characterization of a methacrylated bone-derived hydrogel for bioprinting of in-vitro vascularized tissue constructs	22
Bioprinted microvasculature: progressing from structure to function	22
Core–shell bioprinting as a strategy to apply differentiation factors in a spatially defined manner inside osteochondral tissue substitutes	22
Polydopamine-coated polycaprolactone/carbon nanotube fibrous scaffolds loaded with brain-derived neurotrophic factor for peripheral nerve regeneration	22
3D printing of inorganic-biopolymer composites for bone regeneration	21

Rapid multilayer microfabrication for modeling organotropic metastasis in breast cancer	21
Development of human-derived, three-dimensional respiratory epithelial tissue constructs with perfusable microvasculature on a high-throughput microfluidics screening platform	21
Printability and bio-functionality of a shear thinning methacrylated xanthan–gelatin composite bioink	21
Micro-electrode channel guide (µECG) technology: an online method for continuous electrical recording in a human beating heart-on-chip	21
3D printing of sacrificial thioester elastomers using digital light processing for templating 3D organoid structures in soft biomatrices	21
A simplified yet enhanced and versatile microfluidic platform for cyclic cell stretching on an elastic polymer	20
Controllable assembly of skeletal muscle-like bundles through 3D bioprinting	20
Bilayer silk fibroin/sodium alginate scaffold promotes vascularization and advances inflammation stage in full-thickness wound	20
Hybrid extracellular vesicles-liposome incorporated advanced bioink to deliver microRNA	20
Architected fibrous scaffolds for engineering anisotropic tissues	20
Angiogenic factors secreted from human ASC spheroids entrapped in an alginate-based hierarchical structure via combined 3D printing/electrospinning system	20
A multifunctional micropore-forming bioink with enhanced anti-bacterial and anti-inflammatory properties	20
Functional evaluation of prevascularization in one-stage versus two-stage tissue engineering approach of human bio-artificial muscle	20
Core–shell bioprinting of vascularized in vitro liver sinusoid models	20
Manufacturing of self-standing multi-layered 3D-bioprinted alginate-hyaluronate constructs by controlling the cross-linking mechanisms for tissue engineering applications	19
Biofabrication of vasculature in microphysiological models of bone	19
A perfusable vascularized full-thickness skin model for potential topical and systemic applications	19
Coaxial printing of double-layered and free-standing blood vessel analogues without ultraviolet illumination for high-volume vascularised tissue	19
Expanding sacrificially printed microfluidic channel-embedded paper devices for construction of volumetric tissue models in vitro	19
Constructing high-strength nano-micro fibrous woven scaffolds with native-like anisotropic structure and immunoregulatory function for tendon repair and regeneration	19
Mechanically and biologically promoted cell-laden constructs generated using tissue-specific bioinks for tendon/ligament tissue engineering applications	19
3D-printed bioceramic scaffolds with Fe₃S₄ microflowers for magnetothermal and chemodynamic therapy of bone tumor and regeneration of bone defects	19
Hyaluronic acid based next generation bioink for 3D bioprinting of human stem cell derived corneal stromal model with innervation	19
3D bioassembly of cell-instructive chondrogenic and osteogenic hydrogel microspheres containing allogeneic stem cells for hybrid biofabrication of osteochondral constructs	19
1D and 2D error assessment and correction for extrusion-based bioprinting using process sensing and control strategies	19
3D bioprinting of dECM/Gel/QCS/nHAp hybrid scaffolds laden with mesenchymal stem cell-derived exosomes to improve angiogenesis and osteogenesis	19
Direct extrusion of individually encapsulated endothelial and smooth muscle cells mimicking blood vessel structures and vascular native cell alignment	19
3D bioprinting of osteon-mimetic scaffolds with hierarchical microchannels for vascularized bone tissue regeneration	18
In vivo organized neovascularization induced by 3D bioprinted endothelial-derived extracellular vesicles	18
Study of the process-induced cell damage in forced extrusion bioprinting	18
Bio-inspired zonal-structured matrices for bone-cartilage interface engineering	18
Stem cell spheroid engineering with osteoinductive and ROS scavenging nanofibers for bone regeneration	18
An engineered neurovascular unit for modeling neuroinflammation	18
Human gelatin-based composite hydrogels for osteochondral tissue engineering and their adaptation into bioinks for extrusion, inkjet, and digital light processing bioprinting	18
Valve-based consecutive bioprinting method for multimaterial tissue-like constructs with controllable interfaces	18
Low temperature hybrid 3D printing of hierarchically porous bone tissue engineering scaffolds with in situ delivery of osteogenic peptide and mesenchymal stem cells	18
Testis on a chip—a microfluidic three-dimensional culture system for the development of spermatogenesis in-vitro	18
Micropatterned conductive elastomer patch based on poly (glycerol sebacate)-graphene for cardiac tissue repair	18
3D bioprinted tumor model with extracellular matrix enhanced bioinks for nanoparticle evaluation	18
Development of a novel dual reproductive organ on a chip: recapitulating bidirectional endocrine crosstalk between the uterine endometrium and the ovary	17
Long-term mechanical loading is required for the formation of 3D bioprinted functional osteocyte bone organoids	17
Biofabrication of muscle fibers enhanced with plant viral nanoparticles using surface chaotic flows	17
User-friendly microfluidic manufacturing of hydrogel microspheres with sharp needle	17
Enhancing islet transplantation using a biocompatible collagen-PDMS bioscaffold enriched with dexamethasone-microplates	17