Alzheimers Research & Therapy

Papers
(The TQCC of Alzheimers Research & Therapy is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2021-08-01 to 2025-08-01.)
ArticleCitations
Comparing a pre-defined versus deep learning approach for extracting brain atrophy patterns to predict cognitive decline due to Alzheimer’s disease in patients with mild cognitive symptoms183
Correction: 18F-FDG PET can effectively rule out conversion to dementia and the presence of CSF biomarker of neurodegeneration: a real-world data analysis179
Lower activity of cholesteryl ester transfer protein (CETP) and the risk of dementia: a Mendelian randomization analysis136
Granulovacuolar degeneration bodies are independently induced by tau and α-synuclein pathology130
Greater baseline cortical atrophy in the dorsal attention network predicts faster clinical decline in Posterior Cortical Atrophy125
A biomarker-validated time scale in years of disease progression has identified early- and late-onset subgroups in sporadic Alzheimer’s disease119
An association of CSF apolipoprotein E glycosylation and amyloid-beta 42 in individuals who carry the APOE4 allele111
Genetic and clinical landscape of Chinese frontotemporal dementia: dominance of TBK1 and OPTN mutations109
Investigating the Aβ and tau pathology in autosomal dominant Alzheimer’s disease: insights from hybrid PET/MRI and network mapping106
Near-infrared light reduces β-amyloid-stimulated microglial toxicity and enhances survival of neurons: mechanisms of light therapy for Alzheimer’s disease101
Impact of gender on the willingness to participate in clinical trials and undergo related procedures in individuals from an Alzheimer’s prevention research cohort99
Linking oxysterols and different stages of mild cognitive impairment: insights from gut metabolites and N6-methyladenosine94
Development of a Japanese polygenic risk score model for amyloid-β PET imaging in Alzheimer’s disease84
The economic burden of subjective cognitive decline, mild cognitive impairment and Alzheimer's dementia: excess costs and associated clinical and risk factors84
A multicenter, randomized, double-blind, placebo-controlled ascending dose study to evaluate the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD) effects of Posiphen in subjects wi81
Cornuside alleviates cognitive impairments induced by Aβ1−42 through attenuating NLRP3-mediated neurotoxicity by promoting mitophagy80
Effect of the ABCA1 agonist CS-6253 on amyloid-β and lipoprotein metabolism in cynomolgus monkeys78
High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer’s disease77
Prominent tauopathy and intracellular β-amyloid accumulation triggered by genetic deletion of cathepsin D: implications for Alzheimer disease pathogenesis70
Association of modifiable risk factors with progression to dementia in relation to amyloid and tau pathology70
Serum phosphorylated tau protein 181 and neurofilament light chain in cognitively impaired heart failure patients69
Parsing heterogeneity within dementia with Lewy bodies using clustering of biological, clinical, and demographic data68
Serum and cerebrospinal fluid neurofilament light chain and glial fibrillary acid protein levels in early and advanced stages of cerebral amyloid Angiopathy65
Issues and recommendations for the residual approach to quantifying cognitive resilience and reserve61
Dynamic reciprocal relationships between cognitive and functional declines along the Alzheimer’s disease continuum in the prospective COGICARE study61
Identification of methylation-regulated genes modulating microglial phagocytosis in hyperhomocysteinemia-exacerbated Alzheimer’s disease60
Higher levels of myelin are associated with higher resistance against tau pathology in Alzheimer’s disease59
Tau seeding activity in the cerebrospinal fluid of Alzheimer disease patients predicts short-term cognitive decline59
Apolipoprotein E imbalance in the cerebrospinal fluid of Alzheimer’s disease patients58
Impact of effective connectivity within the Papez circuit on episodic memory: moderation by perivascular space function58
Correction: Applicability of in vivo staging of regional amyloid burden in a cognitively normal cohort with subjective memory complaints: the INSIGHT-preAD study58
Functional gradients of the medial parietal cortex in a healthy cohort with family history of sporadic Alzheimer’s disease57
Navigating the introduction of anti-amyloid therapy in Europe: a position statement by individual members of the EADC56
Analytical and clinical performance of eight Simoa® and Lumipulse® assays for automated measurement of plasma p-tau181 and p-tau21755
CEST imaging combined with 1H-MRS reveal the neuroprotective effects of riluzole by improving neurotransmitter imbalances in Alzheimer’s disease mice55
Mapping the long-term delayed recall-based cortex-hippocampus network constrained by the structural and functional connectome: a case-control multimodal MRI study54
A multiscale brain network model links Alzheimer’s disease-mediated neuronal hyperactivity to large-scale oscillatory slowing53
Genome-wide association studies of Alzheimer’s disease and related disorders stratified by sex, onset age, and Apolipoprotein E genotype reveal novel risk loci in African Americans53
Whole-brain modeling of the differential influences of amyloid-beta and tau in Alzheimer’s disease53
The age-specific comorbidity burden of mild cognitive impairment: a US claims database study52
Serum neurofilament light chain level as a predictor of cognitive stage transition51
Digital Clock and Recall is superior to the Mini-Mental State Examination for the detection of mild cognitive impairment and mild dementia50
Health-related quality of life in subjective cognitive decline and mild cognitive impairment: a longitudinal cohort analysis50
Cognitive composites for genetic frontotemporal dementia: GENFI-Cog50
Hormone therapy is associated with lower Alzheimer’s disease tau biomarkers in post-menopausal females -evidence from two independent cohorts50
Cerebral Aβ deposition precedes reduced cerebrospinal fluid and serum Aβ42/Aβ40 ratios in the AppNL−F/NL−F knock-in mouse model of Alzheimer’s disease49
The cerebrospinal fluid biomarker ratio Aβ42/40 identifies amyloid positron emission tomography positivity better than Aβ42 alone in a heterogeneous memory clinic cohort49
The autocrine motility factor receptor delays the pathological progression of Alzheimer’s disease via regulating the ubiquitination-mediated degradation of APP47
Readthrough isoform of aquaporin-4 (AQP4) as a therapeutic target for Alzheimer’s disease and other proteinopathies47
Dementia risk communication. A user manual for Brain Health Services—part 3 of 647
Correction: Comparative evaluation of clinical and cerebrospinal fluid biomarker characteristics in rapidly and non‑rapidly progressive Alzheimer’s disease46
Antiherpetic drugs: a potential way to prevent Alzheimer’s disease?46
Long-term low-dose acetylsalicylic use shows protective potential for the development of both vascular dementia and Alzheimer’s disease in patients with coronary heart disease but not in other individ45
Head-to-head comparison of tau PET tracers [18F]PI-2620 and [18F]RO948 in non-demented individuals with brain amyloid deposition: the TAU-PET FACEHBI cohort45
An improved immunoassay detects Aβ oligomers in human biofluids: their CSF levels rise with tau and phosphotau levels44
Associations between different tau-PET patterns and longitudinal atrophy in the Alzheimer’s disease continuum: biological and methodological perspectives from disease heterogeneity42
Early visual alterations in individuals at-risk of Alzheimer’s disease: a multidisciplinary approach42
Quantification of identifying cognitive impairment using olfactory-stimulated functional near-infrared spectroscopy with machine learning: a post hoc analysis of a diagnostic trial and validation of a42
The role of structural and functional parameters in designing pathology-specific tDCS protocols for primary progressive aphasia42
Development of multivariable prediction models for institutionalization and mortality in the full spectrum of Alzheimer’s disease42
Subjective cognitive complaints and blood biomarkers of neurodegenerative diseases: a longitudinal cohort study42
Association between ATN profiles and mortality in a clinical cohort of patients with cognitive disorders41
Association of peripheral immunity with cognition, neuroimaging, and Alzheimer’s pathology41
Perivascular space enlargement accelerates in ageing and Alzheimer’s disease pathology: evidence from a three-year longitudinal multicentre study41
Correction: A randomized, double-blind, phase 2b proof-of-concept clinical trial in early Alzheimer’s disease with lecanemab, an anti-Aβ protofibril antibody40
Divergent brain regional atrophy and associated fiber disruption in amnestic and non-amnestic MCI40
Dynamic network model reveals distinct tau spreading patterns in early- and late-onset Alzheimer disease39
Characterization of preclinical Alzheimer’s disease model: spontaneous type 2 diabetic cynomolgus monkeys with systemic pro-inflammation, positive biomarkers and developing AD-like pathology39
The interrelationships of CSF sTREM2, AD pathology, minimal depressive symptoms, and cognition in non-demented adults39
Cross-cultural effects of reminiscence therapy on life satisfaction and autobiographical memory of older adults: a pilot study across Mexico and Spain39
Sex-specific risk factors and clinical dementia outcomes for white matter hyperintensities in a large South Korean cohort38
Elevated Aβ aggregates in feces from Alzheimer’s disease patients: a proof-of-concept study38
Plasma neuregulin 1 as a synaptic biomarker in Alzheimer’s disease: a discovery cohort study38
Clinical and biological relevance of glial fibrillary acidic protein in Alzheimer’s disease38
The identification and cognitive correlation of perfusion patterns measured with arterial spin labeling MRI in Alzheimer’s disease37
Choroid plexus volume as a novel candidate neuroimaging marker of the Alzheimer’s continuum36
Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia35
Distinct effects of blood pressure parameters on Alzheimer’s and vascular markers in 1,952 Asian individuals without dementia35
White matter hyperintensities are a prominent feature of autosomal dominant Alzheimer’s disease that emerge prior to dementia35
Cognitive decline profiles associated with lewy pathology in the context of Alzheimer’s disease neuropathologic change34
Dementia with Lewy bodies and gait neural basis: a cross-sectional study34
Synaptic protein CSF levels relate to memory scores in individuals without dementia34
Correction: Baseline structural MRI and plasma biomarkers predict longitudinal structural atrophy and cognitive decline in early Alzheimer’s disease34
The associations of herpes simplex virus and varicella zoster virus infection with dementia: a nationwide retrospective cohort study33
Evaluating the diagnostic performance of six plasma biomarkers for Alzheimer’s disease and other neurodegenerative dementias in a large Chinese cohort33
Amyloid PET across the cognitive spectrum in former professional and college American football players: findings from the DIAGNOSE CTE Research Project33
18F-FDG PET can effectively rule out conversion to dementia and the presence of CSF biomarker of neurodegeneration: a real-world data analysis31
Development and assessment of algorithms for predicting brain amyloid positivity in a population without dementia31
Meta-analysis of cerebrospinal fluid neuron-specific enolase levels in Alzheimer’s disease, Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy31
Rescue of protein dyshomeostasis in hippocampal astrocytes from an Alzheimer’s disease mouse model by stabilizing ER-mitochondrial interactions at a 20 nm distance30
The reporting of neuropsychiatric symptoms in electronic health records of individuals with Alzheimer’s disease: a natural language processing study30
Different associations between amyloid-βeta 42, amyloid-βeta 40, and amyloid-βeta 42/40 with soluble phosphorylated-tau and disease burden in Alzheimer’s disease: a cerebrospinal fluid and fluorodeoxy30
A longitudinal study on quality of life along the spectrum of Alzheimer’s disease30
Social frailty and its association with cognitive trajectories in older adults: a prospective cohort study29
Associations of resting heart rate with incident dementia, cognition, and brain structure: a prospective cohort study of UK biobank29
White matter hyperintensities and smaller cortical thickness are associated with neuropsychiatric symptoms in neurodegenerative and cerebrovascular diseases29
Alzheimer’s and neurodegenerative disease biomarkers in blood predict brain atrophy and cognitive decline29
Brain reserve contributes to distinguishing preclinical Alzheimer’s stages 1 and 229
Accuracy of plasma Aβ40, Aβ42, and p-tau181 to detect CSF Alzheimer’s pathological changes in cognitively unimpaired subjects using the Lumipulse automated platform29
PACAP–Sirtuin3 alleviates cognitive impairment through autophagy in Alzheimer’s disease28
Nanoscale alterations in GABAB receptors and GIRK channel organization on the hippocampus of APP/PS1 mice28
Multi-omics analyses identify gut microbiota-fecal metabolites-brain-cognition pathways in the Alzheimer’s disease continuum28
Predicting conversion of brain β-amyloid positivity in amyloid-negative individuals28
Clusters of co-abundant proteins in the brain cortex associated with fronto-temporal lobar degeneration28
Association of midlife body-weight variability and cycles with earlier dementia onset: a nationwide cohort study27
Correction: Updated safety results from phase 3 lecanemab study in early Alzheimer’s disease27
evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic Alzheimer’s disea27
Loss of perivascular aquaporin-4 localization impairs glymphatic exchange and promotes amyloid β plaque formation in mice27
Comparison and aggregation of event sequences across ten cohorts to describe the consensus biomarker evolution in Alzheimer’s disease27
Letter to the Editor Authors’ Response: Choroid and choriocapillaris changes in early-stage Parkinson’s disease: a swept-source optical coherence tomography angiography-based cross-sectional study27
In vivo staging of regional amyloid progression in healthy middle-aged to older people at risk of Alzheimer’s disease27
Plasma biomarkers for early detection of alzheimer’s disease: a cross-sectional study in a Japanese cohort26
Neuron-derived extracellular vesicles in blood reveal effects of exercise in Alzheimer’s disease26
Communication about diagnosis, prognosis, and prevention in the memory clinic: perspectives of European memory clinic professionals26
Prediction of conversion from mild cognitive impairment to Alzheimer’s disease and simultaneous feature selection and grouping using Medicaid claim data26
β-Amyloid in blood neuronal-derived extracellular vesicles is elevated in cognitively normal adults at risk of Alzheimer’s disease and predicts cerebral amyloidosis26
Multi-omics analysis reveals the key factors involved in the severity of the Alzheimer’s disease26
Potential role of Amyloid-β on the association between Orexin-A and blood-brain barrier leakage of globus pallidus in Alzheimer’s disease and dementia with lewy bodies25
The apolipoprotein receptor LRP3 compromises APP levels25
Towards a national registry for Alzheimer’s disease and related dementias: rationale, design, and initial observations of the ABOARD cohort25
How does apolipoprotein E genotype influence the relationship between physical activity and Alzheimer’s disease risk? A novel integrative model25
Predicting progression and cognitive decline in amyloid-positive patients with Alzheimer’s disease25
Response to Xing et al.: post-marketing safety concerns with Lecanemab: a pharmacovigilance study based on the FDA adverse event reporting system database25
Comparison of plasma and neuroimaging biomarkers to predict cognitive decline in non-demented memory clinic patients25
Longitudinal resting-state EEG in amyloid-positive patients along the Alzheimer’s disease continuum: considerations for clinical trials24
Influence of co-pathology on CSF and plasma synaptic markers SNAP25 and VAMP2 in Alzheimer’s disease and Parkinson’s disease24
Association of Alzheimer’s disease polygenic risk scores with amyloid accumulation in cognitively intact older adults24
Subclinical carotid artery atherosclerosis and cognitive function in older adults24
Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I-UDSNB 1.0): development and normative data24
Cognitive impairment indicator for the neuropsychological test batteries in the Canadian Longitudinal Study on Aging: definition and evidence for validity24
Quantitative estimate of cognitive resilience and its medical and genetic associations24
A longitudinal study of the 5xFAD mouse retina delineates Amyloid beta (Aβ)-mediated retinal pathology from age-related changes23
Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer’s disease23
Correction to: Preservation of dendritic spine morphology and postsynaptic signaling markers after treatment with solid lipid curcumin particles in the 5xFAD mouse model of Alzheimer’s amyloidosis23
Correction: Reduction of NgR in perforant path decreases amyloid-β peptide production and ameliorates synaptic and cognitive deficits in APP/PS1 mice23
Disruption of early visual processing in amyloid-positive healthy individuals and mild cognitive impairment23
Relationships of change in Clinical Dementia Rating (CDR) on patient outcomes and probability of progression: observational analysis23
Exploring the potential of fully automated LUMIPULSE G plasma assays for detecting Alzheimer’s disease pathology23
Multidomain interventions: state-of-the-art and future directions for protocols to implement precision dementia risk reduction. A user manual for Brain Health Services—part 4 of 623
REM sleep is associated with the volume of the cholinergic basal forebrain in aMCI individuals23
Clinical and analytical comparison of six Simoa assays for plasma P-tau isoforms P-tau181, P-tau217, and P-tau23123
How healthy participants value additional diagnostic testing with amyloid-PET in patients diagnosed with mild cognitive impairment — a bidding game experiment23
Neuronal transcriptome, tau and synapse loss in Alzheimer’s knock-in mice require prion protein23
Apolipoprotein E and sex modulate fatty acid metabolism in a prospective observational study of cognitive decline22
The role of type 2 diabetes in the association between habitual glucosamine use and dementia: a prospective cohort study22
Circular RNA APP contributes to Alzheimer’s disease pathogenesis by modulating microglial polarization via miR-1906/CLIC1 axis22
Altered basal forebrain function during whole-brain network activity at pre- and early-plaque stages of Alzheimer’s disease in TgF344-AD rats22
Alteration of medial temporal lobe metabolism related to Alzheimer’s disease and dementia with lewy bodies22
Axonal degeneration and amyloid pathology predict cognitive decline beyond cortical atrophy22
Methodological quality of systematic reviews on treatments for Alzheimer’s disease: a cross-sectional study21
A polygenic risk score for Alzheimer’s disease constructed using APOE-region variants has stronger association than APOE alleles with mild cognitive impairment in Hispanic/Latino adults in the U.S.21
Purpose in life promotes resilience to age-related brain burden in middle-aged adults21
Correction: Impact of cumulative exposure to anticholinergic and sedative drugs on cognition in older adults: a memory clinic cohort study21
Neurodegenerative biomarkers in different chambers of the eye relative to plasma: an agreement validation study21
Reference intervals for plasma amyloid-β, total tau, and phosphorylated tau181 in healthy elderly Chinese individuals without cognitive impairment21
Tau-related grey matter network breakdown across the Alzheimer’s disease continuum21
Diabetes status, duration, and risk of dementia among ischemic stroke patients21
The impact of subthreshold levels of amyloid deposition on conversion to dementia in patients with amyloid-negative amnestic mild cognitive impairment21
Lipidomics profiling reveals distinct patterns of plasma sphingolipid alterations in Alzheimer’s disease and vascular dementia21
Genome-wide association study and polygenic risk scores of retinal thickness across the cognitive continuum: data from the NORFACE cohort21
Glucosylceramide synthase inhibition reduces ganglioside GM3 accumulation, alleviates amyloid neuropathology, and stabilizes remote contextual memory in a mouse model of Alzheimer’s disease21
Novel CSF β-synuclein-specific assays signal early synaptic degeneration in Alzheimer’s disease20
The course of primary progressive aphasia diagnosis: a cross-sectional study20
Small vessel cerebrovascular disease is associated with cognition in prospective Alzheimer’s clinical trial participants20
Restless leg syndrome and risk of all-cause dementia: a nationwide retrospective cohort study20
High-fat diet-induced atherosclerosis promotes neurodegeneration in the triple transgenic (3 × Tg) mouse model of Alzheimer’s disease associated with chronic platelet activation20
Anticipatory reaching motor behavior characterizes patients within the Alzheimer’s disease continuum in a virtual reality environment20
Chemical genetic activation of the cholinergic basal forebrain hippocampal circuit rescues memory loss in Alzheimer’s disease20
The presence of circulating human apolipoprotein J reduces the occurrence of cerebral microbleeds in a transgenic mouse model with cerebral amyloid angiopathy20
The relationship between retinal layers and brain areas in asymptomatic first-degree relatives of sporadic forms of Alzheimer’s disease: an exploratory analysis20
Fibre density and cross-section associate with hallmark pathology in early Alzheimer’s disease20
Optimizing midlife metabolic syndrome thresholds for dementia: a prospective study of two UK population-based cohorts20
Exploring sex differences in Alzheimer’s disease: a comprehensive analysis of a large patient cohort from a memory unit20
Cerebrospinal fluid α-synuclein adds the risk of cognitive decline and is associated with tau pathology among non-demented older adults20
Alzheimer’s polygenic risk scores, APOE, Alzheimer’s disease risk, and dementia-related blood biomarker levels in a population-based cohort study followed over 17 years20
The effects of a moderate physical activity intervention on physical fitness and cognition in healthy elderly with low levels of physical activity: a randomized controlled trial19
Recruitment across two decades of NIH-funded Alzheimer’s disease clinical trials19
Correction: Italian adaptation of the Uniform Data Set Neuropsychological Test Battery (I‑UDSNB 1.0): development and normative data19
Prodromal frontotemporal dementia: clinical features and predictors of progression19
Molecular insights into sex-specific metabolic alterations in Alzheimer’s mouse brain using multi-omics approach19
Combining plasma Aβ and p-tau217 improves detection of brain amyloid in non-demented elderly19
Frontotemporal structure preservation underlies the protective effect of lifetime intellectual cognitive reserve on cognition in the elderly19
Tau levels are higher in objective subtle cognitive decline but not subjective memory complaint18
Correction: Short‑term variability of Alzheimer’s disease plasma biomarkers in a mixed memory clinic cohort18
Soluble SorLA in CSF, a novel biomarker to explore disrupted trafficking of SorLA protein in Alzheimer disease18
Longitudinal validation of cognitive reserve proxy measures: a cohort study in a rural Chinese community18
Correction: Abdominal obesity and the risk of young-onset dementia in women: a nationwide cohort study18
Correction to: Psychotherapeutic interventions in individuals at risk for Alzheimer’s dementia: a systematic review18
Post hoc analysis of ADAMANT, a phase 2 clinical trial of active tau immunotherapy with AADvac1 in patients with Alzheimer’s disease, positive for plasma p-tau21718
Insomnia, early and late rising are associated with small hippocampal volume and large white matter hyperintensity burden18
Deletion of Abi3/Gngt2 influences age-progressive amyloid β and tau pathologies in distinctive ways18
Plasma amyloid-beta oligomer is related to subjective cognitive decline and brain amyloid status17
Predicting progression from subjective cognitive decline to mild cognitive impairment or dementia based on brain atrophy patterns17
Diagnostic performance of automated plasma amyloid-β assays combined with pre-analytical immunoprecipitation17
Diagnostic value of serum versus plasma phospho-tau for Alzheimer’s disease17
Clinical implications of head trauma in frontotemporal dementia and primary progressive aphasia17
Intermittent hypoxia training enhances Aβ endocytosis by plaque associated microglia via VPS35-dependent TREM2 recycling in murine Alzheimer’s disease17
Human in vivo evidence of associations between herpes simplex virus and cerebral amyloid-beta load in normal aging17
Age of onset moderates the effects of Vascular Risk Factors on Neurodegeneration, Blood-Brain-Barrier permeability, and cognitive decline in Alzheimer’s Disease17
N, N-Dimethyltryptamine, a natural hallucinogen, ameliorates Alzheimer’s disease by restoring neuronal Sigma-1 receptor-mediated endoplasmic reticulum-mitochondria crosstalk17
Age, vascular disease, and Alzheimer’s disease pathologies in amyloid negative elderly adults17
NeuroEPO plus (NeuralCIM®) in mild-to-moderate Alzheimer’s clinical syndrome: the ATHENEA randomized clinical trial17
Hampered AMPK-ULK1 cascade in Alzheimer’s disease (AD) instigates mitochondria dysfunctions and AD-related alterations which are alleviated by metformin17
Rationale and design of the BeyeOMARKER study: prospective evaluation of blood- and eye-based biomarkers for early detection of Alzheimer’s disease pathology in the eye clinic17
Explaining the association between social and lifestyle factors and cognitive functions: a pathway analysis in the Memento cohort17
Biophysical models applied to dementia patients reveal links between geographical origin, gender, disease duration, and loss of neural inhibition16
N-Methyl-D-aspartate (NMDA) and cannabinoid CB2 receptors form functional complexes in cells of the central nervous system: insights into the therapeutic potential of neuronal and microglial NMDA rece16
White matter hyperintensity patterns: associations with comorbidities, amyloid, and cognition16
The relationship of insulin resistance and diabetes to tau PET SUVR in middle-aged to older adults16
Network dynamics-based subtyping of Alzheimer’s disease with microglial genetic risk factors16
Correction: Diagnostic performance of plasma pTau217, pTau181, Aβ1‑42 and Aβ1‑40 in the LUMIPULSE automated platform for the detection of Alzheimer disease16
Amyloid-PET imaging predicts functional decline in clinically normal individuals16
Comparative evaluation of clinical and cerebrospinal fluid biomarker characteristics in rapidly and non-rapidly progressive Alzheimer’s disease16
Effects of APOE2 and APOE4 on brain microstructure in older adults: modification by age, sex, and cognitive status16
Prevalence of treated patients with Alzheimer’s disease: current trends and COVID-19 impact16
Subjective cognitive decline predicts longitudinal neuropsychological test performance in an unsupervised online setting in the Brain Health Registry16
Perivascular space and white matter hyperintensities in Alzheimer’s disease: associations with disease progression and cognitive function16
The effects of imaging markers on clinical trajectory in cerebral amyloid angiopathy: a longitudinal study in a memory clinic16
Rotation errors in path integration are associated with Alzheimer’s disease tau pathology: a cross-sectional study16
Is later-life depression a risk factor for Alzheimer’s disease or a prodromal symptom: a study using post-mortem human brain tissue?16
Psychotherapeutic interventions in individuals at risk for Alzheimer’s dementia: a systematic review16
Response to Schmidt et al.: Lower activity of cholesteryl ester transfer protein (CETP) and the risk of dementia: a Mendelian randomization analysis16
Associations of computer gaming with incident dementia, cognitive functions, and brain structure: a prospective cohort study and Mendelian randomization analysis16
Development and validation of a novel predictive model for dementia risk in middle-aged and elderly depression individuals: a large and longitudinal machine learning cohort study15
Neuroimaging of tissue microstructure as a marker of neurodegeneration in the AT(N) framework: defining abnormal neurodegeneration and improving prediction of clinical status15
P2X7 receptor inhibition ameliorates ubiquitin–proteasome system dysfunction associated with Alzheimer’s disease15
Sex differences in neuropsychiatric symptoms in Alzheimer’s disease dementia: a meta-analysis15
Increasing brain glucose metabolism by ligustrazine piperazine ameliorates cognitive deficits through PPARγ-dependent enhancement of mitophagy in APP/PS1 mice15
DNA hypomethylation promotes the expression of CASPASE-4 which exacerbates inflammation and amyloid-β deposition in Alzheimer’s disease15
Identification of profiles associated with conversions between the Alzheimer’s disease stages, using a machine learning approach15
Intracerebral hemorrhage following mild ARIA-H in an APOE ε2 carrier receiving lecanemab15
Could tau-PET imaging contribute to a better understanding of the different patterns of clinical progression in Alzheimer’s disease? A 2-year longitudinal study15
Predicting positron emission tomography brain amyloid positivity using interpretable machine learning models with wearable sensor data and lifestyle factors15
Retinal mid-peripheral capillary free zones are enlarged in cognitively unimpaired older adults at high risk for Alzheimer’s disease15
Inhibition of FAM19A5 reverses synaptic loss and cognitive decline in mouse models of Alzheimer’s disease15
Beyond expectations: investigating nilotinib’s potential in attenuating neurodegeneration in Alzheimer’s disease15
Herpes zoster and long-term risk of subjective cognitive decline15
Stress, depression, and risk of dementia – a cohort study in the total population between 18 and 65 years old in Region Stockholm15
Comparing regional brain uptake of incretin receptor agonists after intranasal delivery in CD-1 mice and the APP/PS1 mouse model of Alzheimer’s disease15
Effects of 52 weeks of precuneus rTMS in Alzheimer’s disease patients: a randomized trial15
Metabolic syndrome biomarkers relate to rate of cognitive decline in MCI and dementia stages of Alzheimer’s disease15
Complaints of daytime sleepiness, insomnia, hypnotic use, and risk of dementia: a prospective cohort study in the elderly15
BMI1 is associated with CSF amyloid-β and rates of cognitive decline in Alzheimer’s disease15
Proteome-wide association studies using summary pQTL data of brain, CSF, and plasma identify 30 risk genes of Alzheimer’s disease dementia15
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