OOIR: Observatory of International Research

Papers

(The TQCC of Nature Reviews Urology is 6. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2020-05-01 to 2024-05-01.)

Article	Citations
Genomic and phenotypic heterogeneity in prostate cancer	221
Epidemiology, definition and treatment of complicated urinary tract infections	134
Epidemiology and genomics of prostate cancer in Asian men	114
The biology and rationale of targeting nectin-4 in urothelial carcinoma	95
Trained immunity as a molecular mechanism for BCG immunotherapy in bladder cancer	94
Genetics of kidney stone disease	87
100 years of Bacillus Calmette–Guérin immunotherapy: from cattle to COVID-19	84
The immune response to infection in the bladder	79
Sperm ion channels and transporters in male fertility and infertility	79
Sarcomatoid renal cell carcinoma: biology, natural history and management	76
Molecular events in neuroendocrine prostate cancer development	68
Exercise-induced myokines and their effect on prostate cancer	61
Serum PSA-based early detection of prostate cancer in Europe and globally: past, present and future	60
Prognostic and predictive biomarkers for immunotherapy in advanced renal cell carcinoma	59
Defining cisplatin eligibility in patients with muscle-invasive bladder cancer	58
Resistance to second-generation androgen receptor antagonists in prostate cancer	58
Recurrence mechanisms of non-muscle-invasive bladder cancer — a clinical perspective	51
Late adverse effects and quality of life in survivors of testicular germ cell tumour	47
An integrated model to assess and treat compulsive sexual behaviour disorder	46
Machine learning for sperm selection	42
Current evidence on screening for renal cancer	41
Understanding genomics and the immune environment of penile cancer to improve therapy	38
Telehealth in urology after the COVID-19 pandemic	38
Neoadjuvant hormonal therapy before radical prostatectomy in high-risk prostate cancer	38
Transient receptor potential channels in sensory mechanisms of the lower urinary tract	35

Toilet-based continuous health monitoring using urine	34
The cognitive effect of anticholinergics for patients with overactive bladder	34
Making love in the time of corona — considering relationships in lockdown	34
Targetable gene fusions and aberrations in genitourinary oncology	32
Proteomic discovery of non-invasive biomarkers of localized prostate cancer using mass spectrometry	31
A global approach to improving penile cancer care	31
Treatment and trials in non-metastatic castration-resistant prostate cancer	31
Definition, diagnosis and management of fetal lower urinary tract obstruction: consensus of the ERKNet CAKUT-Obstructive Uropathy Work Group	31
Advances in sperm analysis: techniques, discoveries and applications	30
Redefining a sexual medicine paradigm: subclinical premature ejaculation as a new taxonomic entity	30
Pelvic organ prolapse and sexual function	30
Preoperative exercise interventions to optimize continence outcomes following radical prostatectomy	30
Human kidney stones: a natural record of universal biomineralization	30
Bladder cancer, inflammageing and microbiomes	29
Salvage therapy for prostate cancer after radical prostatectomy	29
Intermittent versus continuous androgen deprivation therapy for advanced prostate cancer	29
Cannabinoid signalling and effects of cannabis on the male reproductive system	29
Spatiotemporal trends in human semen quality	29
Surgical ergonomics for urologists: a practical guide	28
Molecular determinants of disease severity in urinary tract infection	28
Prostate zones and cancer: lost in transition?	27
Artificial intelligence in academic writing: a paradigm-shifting technological advance	27
Fatty acid metabolism reprogramming in ccRCC: mechanisms and potential targets	27
Perspectives in primary hyperoxaluria — historical, current and future clinical interventions	26
Implications of testicular ACE2 and the renin–angiotensin system for SARS-CoV-2 on testis function	26
Simulating nature in sperm selection for assisted reproduction	26
The dynamic roles of the bladder tumour microenvironment	25
The potential of CAR T cell therapy for prostate cancer	25
Using PSMA imaging for prognostication in localized and advanced prostate cancer	24
Quality checkpoints in the MRI-directed prostate cancer diagnostic pathway	22
Standardization of microbiome studies for urolithiasis: an international consensus agreement	22
Advances in the selection of patients with prostate cancer for active surveillance	21
Practical considerations for prostate hypofractionation in the developing world	21
Complementary roles of surgery and systemic treatment in clear cell renal cell carcinoma	21
Optimizing the diagnosis and management of ductal prostate cancer	20
The current role of MRI for guiding active surveillance in prostate cancer	20
Germline testing and genetic counselling in prostate cancer	20
Rethinking prostate cancer screening: could MRI be an alternative screening test?	20
Surgical management of high-risk, localized prostate cancer	20
Patient-derived tumour models for personalized therapeutics in urological cancers	20
The multifaceted long-term effects of the COVID-19 pandemic on urology	19
Immunomodulation therapy offers new molecular strategies to treat UTI	19
Roles for urothelium in normal and aberrant urinary tract development	18
Using oncolytic viruses to ignite the tumour immune microenvironment in bladder cancer	18
Evolution of the World Health Organization semen analysis manual: where are we?	17
Immune-based therapies in penile cancer	17
Experimental in vitro, ex vivo and in vivo models in prostate cancer research	17
Cellular senescence as a possible link between prostate diseases of the ageing male	17
Introducing PIONEER: a project to harness big data in prostate cancer research	16
Mechanisms of the intestinal and urinary microbiome in kidney stone disease	16

Incorporating palliative care principles to improve patient care and quality of life in urologic oncology	16
The endoplasmic reticulum stress response in prostate cancer	16
Regulation and role of CAMKK2 in prostate cancer	16
The International Penile Prosthesis Implant Consensus Forum: clinical recommendations and surgical principles on the inflatable 3-piece penile prosthesis implant	15
Animal models of naturally occurring stone disease	15
Harnessing the potential of multimodal radiotherapy in prostate cancer	15
Autonomous surgery in the era of robotic urology: friend or foe of the future surgeon?	15
Depression and prostate cancer: implications for urologists and oncologists	14
Urine biomarkers in bladder cancer — current status and future perspectives	14
Are sex disparities in COVID-19 a predictable outcome of failing men’s health provision?	14
Prostate luminal progenitor cells: from mouse to human, from health to disease	14
PBRM1, SETD2 and BAP1 — the trinity of 3p in clear cell renal cell carcinoma	14
Fertility preservation in boys facing gonadotoxic cancer therapy	14
Surgical management of primary severe hypospadias in children: an update focusing on penile curvature	14
Potential role of oxidative stress in the pathogenesis of diabetic bladder dysfunction	14
The Movember Prostate Cancer Landscape Analysis: an assessment of unmet research needs	14
Considering the potential for gene-based therapy in prostate cancer	13
The future of PSMA PET and WB MRI as next-generation imaging tools in prostate cancer	13
Landmarks in the evolution of prostate biopsy	13
The COVID-19 pandemic — what have urologists learned?	13
The testosterone paradox of advanced prostate cancer: mechanistic insights and clinical implications	12
Race and prostate cancer: genomic landscape	12
MRI-guided active surveillance in prostate cancer: not yet ready for practice	12
Galectins as potential therapeutic targets in STIs in the female genital tract	12
Sentinel lymph node biopsy using indocyanine green in penile cancer	12
Advances in stem cell research for the treatment of primary hypogonadism	12
Vaccines as treatments for prostate cancer	12
Host–biomaterial interactions in mesh complications after pelvic floor reconstructive surgery	11
Microfluidics facilitating the use of small extracellular vesicles in innovative approaches to male infertility	11
Clinical use and implications of sexual devices and sexually explicit media	11
Advanced renal cell carcinoma and COVID-19 — a personal perspective	10
Revolutionizing care for rare genitourinary tumours	10
Genetic control of typical and atypical sex development	10
Male infertility and somatic health — insights into lipid damage as a mechanistic link	10
The effect of early puberty suppression on treatment options and outcomes in transgender patients	10
Urinary biomarkers to mitigate diagnostic delay in bladder cancer during the COVID-19 era	10
Therapeutic potential of CDK4/6 inhibitors in renal cell carcinoma	10
Artificial intelligence and urology: ethical considerations for urologists and patients	10
Circulating and urinary tumour DNA in urothelial carcinoma — upper tract, lower tract and metastatic disease	10
Prostate cancer risk, screening and management in patients with germline BRCA1/2 mutations	10
Current and emerging treatment options for premature ejaculation	9
Combination treatment in metastatic prostate cancer: is the bar too high or have we fallen short?	9
Obesity and prostate cancer — microenvironmental roles of adipose tissue	9
Indications and characteristics of penile traction and vacuum erection devices	9
Black lives in urology: addressing the bias and redressing the balance	8
Circadian rhythm and erectile function: is there a penile clock?	8
Lessons learned from the first 15 years of penile transplantation and updates to the Baltimore Criteria	8
Body fluid-derived stem cells — an untapped stem cell source in genitourinary regeneration	8
Inheritance of paternal lifestyles and exposures through sperm DNA methylation	8
Sex differences in bladder cancer: emerging data and call to action	7
Outer membrane vesicle vaccines for Neisseria gonorrhoeae	7
Effect of smoking, hypertension and lifestyle factors on kidney cancer — perspectives for prevention and screening programmes	7
Attention to detail and a permissive set-up: crucial for an effective TURBT	7
Fighting the ‘other pandemic’ — systemic racism in urology	7
Pembrolizumab use in bladder cancer: a tale of two trials	7
AI for prostate cancer diagnosis — hype or today’s reality?	7
The androgen receptor in bladder cancer	6
The potential role of the microbiota in prostate cancer pathogenesis and treatment	6
Refining neoadjuvant therapy clinical trial design for muscle-invasive bladder cancer before cystectomy: a joint US Food and Drug Administration and Bladder Cancer Advocacy Network workshop	6
Human in vitro spermatogenesis as a regenerative therapy — where do we stand?	6
Vitamins as regulators of calcium-containing kidney stones — new perspectives on the role of the gut microbiome	6
Principles and outcomes of gender-affirming vaginoplasty	6
Health-related quality of life after curative treatment for muscle-invasive bladder cancer	6
Sexual health and treatment-related sexual dysfunction in sexual and gender minorities with prostate cancer	6