OOIR: Observatory of International Research

Papers

(The TQCC of Nature Reviews Endocrinology is 15. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-06-01 to 2026-06-01.)

Article	Citations
Exposing skin to ultraviolet irradiation increases food intake in male individuals	972
Immune cell population prevents weight regain	593
Non-nutritive sweeteners — too sweet to be wholesome?	549
Timed high-fat diet feeding restores small bowel circadian rhythms	530
Memory of obesity stored in adipocytes	322
Identification of genetic factors of type 2 diabetes mellitus risk in South Asian populations	271
Author Correction: Adrenocortical stem cells in health and disease	241
The role of DNA damage in diabetic complications	241
The challenges of assessing adiposity in a clinical setting	236
Effects of diet on atherosclerotic plaque development	224
Limiting the use and misuse of liothyronine in hypothyroidism	199
Thyroid function and iodine intake: global recommendations and relevant dietary trends	194
Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead	189
The gut microbiota in obesity and weight management: microbes as friends or foe?	182
Ketosis improves muscle stem cell resilience	158
Patients’ insights into diabetes insipidus	148
Neurons in the diagonal band of Broca moderate food intake	146
Ensuring diverse representation and minimizing conflicts of interest in clinical practice guidelines	144
Reply to ‘Ensuring diverse representation and minimizing conflicts of interest in clinical practice guidelines’	144
Obesity phenotypes: explaining the unexplained	139
Midlife and the menopause transition in type 2 diabetes mellitus prevention	137
A pivotal year for NAFLD and NASH therapeutics	129
Reply to ‘Why the science on T3 and genomics is not settled’	122
Fusion with blood vessel organoids supports pancreatic islet function	121
Steroid hormones as modulators of anti-tumoural immunity	117

The interactions between energy homeostasis and neurovascular plasticity	109
mTORC1 is the central regulator in pancreatic β-cells	102
The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity	101
Primary aldosteronism — a multidimensional syndrome	95
Amylin: emergent therapeutic opportunities in overweight, obesity and diabetes mellitus	92
A role for the kidney in metformin action	87
RalA links obesity and mitochondrial dysfunction	87
Genetic risk scores improve prediction of obesity in survivors of childhood cancer	87
New maps and new challenges in the post-genomic era	87
New role for bone marrow adipocytes in obesity	87
Advances in basic biology and translation in islet research	86
The metabolic mythos of ketones	86
Inflammation-induced adrenal dysfunction	84
Epigenetic effects of maternal type 1 diabetes mellitus	83
Signals from the dorsal motor nucleus of the vagus promote jejunal fat absorption	82
Advances in incretin-based therapeutics for obesity	80
Language evolves — so can you	78
Targeting the incretin system in obesity and type 2 diabetes mellitus	78
Endosomal trafficking in metabolic homeostasis and diseases	76
Luteal phase support in assisted reproductive technology	76
Dysfunctional adipose tissue–lymphatic crosstalk in obesity	75
Endocrinologists gather at ECE 2026	75
Bone and muscle crosstalk in ageing and disease	73
Untangling the pathways of SDHx loss of function	72
Author Correction: Drug Insight: selective agonists and antagonists of the glucocorticoid receptor	71
Leptin–thyroid hormone axis affects energy use in muscle	70
Tracing the biological roots of obesity resistance in humans	68
REG3G — a potential link between the intestinal microbiome and host physiology	68
The metabolic benefits of exercise-induced hepatic autophagy	66
Iatrogenic adrenal insufficiency in adults	66
Potential downsides of calorie restriction	66
The role of ultra-processed food in obesity	60
Islet hormones at the intersection of glucose and amino acid metabolism	60
A global view of hypertensive disorders and diabetes mellitus during pregnancy	58
Length of light exposure alters energy metabolism in mice	55
From the perspective of a scientist with Cushing disease, what did not kill me made my science stronger	54
Vitamin D supplementation and fracture risk	51
GPR110 as a regulator of MASH	51
GLP1 receptor agonist overcomes SGLT2 inhibitor-related overeating	51
Sex hormones in SARS-CoV-2 susceptibility: key players or confounders?	50
The complexity of the relationship between thyroid disease and body weight	50
Metabolic control of feto–placental development and pregnancy outcomes	49
Obesity dysregulates a pituitary–liver axis through disruption of the unfolded protein response	49
Cardiorenal diseases in type 2 diabetes mellitus: clinical trials and real-world practice	48
Why does the immune system destroy pancreatic β-cells but not α-cells in type 1 diabetes?	48
Investigating the effects of artificial sweeteners	48
The autonomic nervous system in the regulation of glucose and lipid metabolism	45
Lipid droplet biogenesis and functions in health and disease	44
Sarcopenic obesity in older adults: a clinical overview	44
Continuous glucose monitoring for the routine care of type 2 diabetes mellitus	43

At the 2022 Congress on Obesity	42
Variation in serotonin 2C receptor linked with obesity and behaviour	42
Engineered Tregs prevent diabetes mellitus in mice	42
Targeting senescent cells in ageing-related endocrine diseases	42
Energy intake at the intersection of the clock and ageing	41
Large study on hormone therapy for transgender youth provides reassurance amid treatment politicization	40
OBEClust: joining forces to prevent obesity	40
ZMIZ1 supports endometrial oestrogen and progesterone signalling	40
Mitigating the environmental effects of healthcare: the role of the endocrinologist	39
Metformin and GDF15: where are we now?	39
Highlights from SfE BES 2026	37
The glymphatic system as a nexus between obesity and neurological diseases	36
Arginine vasopressin deficiency: diagnosis, management and the relevance of oxytocin deficiency	36
Exercise in adults with type 1 diabetes mellitus	36
Growth hormone-releasing hormone and its analogues in health and disease	35
Sertoli cell lysosomal dysfunction drives age-related testicular degeneration	35
The regulation of endocrine-disrupting chemicals to minimize their impact on health	34
Advancing precision nutrition: bridging mechanistic insight and clinical implementation	34
Models of hyperglycaemia in diabetes mellitus and its complications	34
Medically not yet explained symptoms in hypothyroidism	34
Blood-based obesity biomarkers and their relevance for disease risk	34
New genes associated with adult-onset obesity	34
Can obesity pharmacotherapy be used to manage male infertility?	32
GWAS gives insights into glucose regulation	32
International consensus guidelines on the implementation and monitoring of vosoritide therapy in individuals with achondroplasia	32
A mitochondrial trigger for beige adipocyte development	32
Individualized and innovative gender healthcare for transgender and nonbinary youth	31
Interventions in people newly diagnosed with type 1 diabetes mellitus	30
Diabetes mellitus and work participation	30
Brown adipose tissue fights the battle against leukaemia	29
Metabolic effects of gender-affirming hormone therapy	29
The complex effects of dietary restriction on longevity and health	29
Nutrient regulation of bone marrow adipose tissue: skeletal implications of weight loss	29
Masterful papers that broke open understanding of reproductive neuroendocrinology	29
Greater recognition required for thyroid disorders	29
Combination therapy increases human β-cell mass in vivo	29
Highlights from ADA 85th Scientific Sessions	28
The public health burden of diabetes mellitus and thyroid disease: twin epidemics	27
Negative effects of ultra-processed foods beyond increasing calories	27
Knowledge in youth is wisdom in age: involving young people in research	27
Variation in metformin pharmacokinetics	26
Author Correction: International consensus statement on the diagnosis and management of phaeochromocytoma and paraganglioma in children and adolescents	25
Exposure to fat odour during development predisposes offspring to obesity	25
Neurokinin receptor antagonists for vasomotor symptoms: from KNDy neurons to clinical translation	24
Author Correction: Consensus Statement on the definition and classification of metabolic hyperferritinaemia	24
Sex differences in diabetic kidney disease explained	24
Peritumoural adipose tissue protects colorectal cancer from immune attack	24
Monogenic diabetes mellitus hidden in autoantibody-negative diabetes mellitus	23
Unravelling the rise in thyroid cancer incidence and addressing overdiagnosis	23
Highlights from ADA 82nd Scientific Sessions	22
AcroBATics: how dying brown adipocytes trigger browning	22
Antioxidant liver myeloid cell population identified	22
The study that pioneered islet isolation techniques	21
Obesity induces epigenetic memory in innate immune cells	20
Advances in incretin-based drug discovery in 2025	20
Author Correction: Seeing through the fog: a neuroendocrine explanation for post-COVID cognitive deficits	20
Bone fragility in type 2 diabetes mellitus: a lot left to explore	19
Dysfunctional lipid metabolism in ageing muscle: effects on glucose tolerance	19
Skeletal stem and progenitor cells in bone physiology, ageing and disease	18
CAMK1D required for ghrelin-mediated food intake	17
Consensus on acromegaly therapeutic outcomes: an update	17
Genomics suggest role for IGF1 resistance in T2DM	17
New variant for monogenic obesity	17
Current and future pharmacotherapies for obesity in children and adolescents	16
Antigen-specific Treg cells induce infectious tolerance	15
IL-17 has a role in whole-body homeostasis	15
The progesterone receptor’s journey through mouse models	15
Endoscopic sleeve gastroplasty: safe and effective	15