Nature Reviews Endocrinology

Article	Citations
Exposing skin to ultraviolet irradiation increases food intake in male individuals	587
Non-nutritive sweeteners — too sweet to be wholesome?	550
Dexamethasone in patients with diabetes mellitus	510
Exercise-induced plasma factors confer brain benefits	500
CNOT6L regulates hepatokine expression	341
The role of DNA damage in diabetic complications	335
Memory of obesity stored in adipocytes	328
Immune cell population prevents weight regain	328
Identification of genetic factors of type 2 diabetes mellitus risk in South Asian populations	304
Author Correction: Adrenocortical stem cells in health and disease	298
Effects of diet on atherosclerotic plaque development	283
Timed high-fat diet feeding restores small bowel circadian rhythms	275
Limiting the use and misuse of liothyronine in hypothyroidism	219
The gut microbiota in obesity and weight management: microbes as friends or foe?	212
The challenges of assessing adiposity in a clinical setting	166
Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead	166
Thyroid function and iodine intake: global recommendations and relevant dietary trends	163
Type 2 diabetes mellitus in older adults: clinical considerations and management	160
To fast or not to fast — that is the question	156
Metformin reduces ageing adipose senescence	146
Negative regulator of GDF15 signalling identified	137
Iron in adipocytes — a role in gut–adipose crosstalk	133
Ketosis improves muscle stem cell resilience	130
Metabolite levels during the menstrual cycle	127
Obesity phenotypes: explaining the unexplained	127

The emerging osteo-metabolic phenotype of COVID-19: clinical and pathophysiological aspects	122
Reply to ‘Ensuring diverse representation and minimizing conflicts of interest in clinical practice guidelines’	120
Ensuring diverse representation and minimizing conflicts of interest in clinical practice guidelines	119
Research in metabolic ageing — a tale of mice versus humans?	117
A pivotal year for NAFLD and NASH therapeutics	116
The importance of human brown adipose tissue volume	116
Role for exosomes in insulin sensitivity	111
Neurons in the diagonal band of Broca moderate food intake	111
Patients’ insights into diabetes insipidus	106
Handle with care — interpretation, synthesis and dissemination of data on paracetamol in pregnancy	102
Amylin: emergent therapeutic opportunities in overweight, obesity and diabetes mellitus	101
mTORC1 is the central regulator in pancreatic β-cells	101
The interactions between energy homeostasis and neurovascular plasticity	97
GDF15: emerging biology and therapeutic applications for obesity and cardiometabolic disease	95
One hundred years of insulin therapy	93
The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity	93
Primary aldosteronism — a multidimensional syndrome	92
Steroid hormones as modulators of anti-tumoural immunity	90
A role for phosphocreatine in adipose inflammation	89
Ketogenic modification of the liver proteome	84
Genetic risk scores improve prediction of obesity in survivors of childhood cancer	83
New role for bone marrow adipocytes in obesity	81
Role of extracellular vesicles in β-cell failure	78
Signals from the dorsal motor nucleus of the vagus promote jejunal fat absorption	77
A role for the kidney in metformin action	76
Urocortin 3 function in glucose metabolism	76
RalA links obesity and mitochondrial dysfunction	75
Progress in islet transplantation is more important than ever	73
The metabolic mythos of ketones	72
GLP1–oestrogen agonist protects β-cells from insulin-deficient diabetes mellitus	71
Stem-cell derived pancreatic endoderm cells in the treatment of T1DM	67
Advances in basic biology and translation in islet research	67
Inflammation-induced adrenal dysfunction	66
Bone and muscle crosstalk in ageing and disease	64
Advances in incretin-based therapeutics for obesity	63
Targeting the incretin system in obesity and type 2 diabetes mellitus	60
Endosomal trafficking in metabolic homeostasis and diseases	59
Luteal phase support in assisted reproductive technology	58
Untangling the pathways of SDHx loss of function	54
The metabolic benefits of exercise-induced hepatic autophagy	53
Triggering puberty in primates: is it NPY?	53
Leptin–thyroid hormone axis affects energy use in muscle	52
A multi-omics roadmap of β-cell failure in type 2 diabetes mellitus	52
Potential downsides of calorie restriction	50
REG3G — a potential link between the intestinal microbiome and host physiology	49
Tracing the biological roots of obesity resistance in humans	49
Skeletal and extraskeletal disorders of biomineralization	48
Iatrogenic adrenal insufficiency in adults	47
New insights into β-cell failure, regeneration and replacement	46
Islet hormones at the intersection of glucose and amino acid metabolism	45

A global view of hypertensive disorders and diabetes mellitus during pregnancy	45
HIF1α inhibition preserves β-cell function	44
Length of light exposure alters energy metabolism in mice	44
Potential role for follicular Treg cells in T1DM	43
Unravelling umami-induced obesity	42
Remission of T2DM requires early diagnosis and substantial weight reduction	41
GLP1 receptor agonist overcomes SGLT2 inhibitor-related overeating	41
From the perspective of a scientist with Cushing disease, what did not kill me made my science stronger	40
Obesity dysregulates a pituitary–liver axis through disruption of the unfolded protein response	40
Melatonin prevents diabetes mellitus-induced bone loss	39
Vitamin D supplementation and fracture risk	38
Investigating the effects of artificial sweeteners	37
Sex hormones in SARS-CoV-2 susceptibility: key players or confounders?	37
Why does the immune system destroy pancreatic β-cells but not α-cells in type 1 diabetes?	37
Lipid droplet biogenesis and functions in health and disease	36
Cardiorenal diseases in type 2 diabetes mellitus: clinical trials and real-world practice	36
Continuous glucose monitoring for the routine care of type 2 diabetes mellitus	36
At the 2022 Congress on Obesity	35
Engineered Tregs prevent diabetes mellitus in mice	35
Sarcopenic obesity in older adults: a clinical overview	35
GnRH pulses affect ageing in male mice	32
Role of bile acids in controlling satiety	31
Variation in serotonin 2C receptor linked with obesity and behaviour	30
The glymphatic system as a nexus between obesity and neurological diseases	30
Targeting senescent cells in ageing-related endocrine diseases	30
Energy intake at the intersection of the clock and ageing	28
Exosomes as novel biomarkers in metabolic disease and obesity-related cancers	28
Large study on hormone therapy for transgender youth provides reassurance amid treatment politicization	28
Molecular transducers and the cardiometabolic benefits of exercise	28
Mitigating the environmental effects of healthcare: the role of the endocrinologist	28
Sertoli cell lysosomal dysfunction drives age-related testicular degeneration	26
Growth hormone-releasing hormone and its analogues in health and disease	26
Epigenetics of type 2 diabetes mellitus and weight change — a tool for precision medicine?	26
Metformin and GDF15: where are we now?	26
New genes associated with adult-onset obesity	25
Exercise in adults with type 1 diabetes mellitus	25
Adaptive immune cells shape obesity-associated type 2 diabetes mellitus and less prominent comorbidities	25
Arginine vasopressin deficiency: diagnosis, management and the relevance of oxytocin deficiency	25
A protective role for insulin in acute pancreatitis	24
The largest study of genetics of T1DM	24
A mitochondrial trigger for beige adipocyte development	22
GWAS gives insights into glucose regulation	21
Mitochondria transported from adipocytes in extracellular vesicles	21
Interventions in people newly diagnosed with type 1 diabetes mellitus	21
Highlights from SfE BES 2021	20
International consensus guidelines on the implementation and monitoring of vosoritide therapy in individuals with achondroplasia	20
TIM4+ adipose tissue-resident macrophages: new modulators of adiposity	20
Nutrient regulation of bone marrow adipose tissue: skeletal implications of weight loss	20
Paracetamol use in pregnancy — caution over causal inference from available data	20
Individualized and innovative gender healthcare for transgender and nonbinary youth	19
The regulation of endocrine-disrupting chemicals to minimize their impact on health	18
Medically not yet explained symptoms in hypothyroidism	18
Sex differences in diabetic kidney disease explained	17
Epigenetic inheritance of polycystic ovary syndrome — challenges and opportunities for treatment	17
Brown adipose tissue fights the battle against leukaemia	17
SRC2 controls the refeeding response in mice	16
Variation in metformin pharmacokinetics	16
Combination therapy increases human β-cell mass in vivo	16
Author Correction: Consensus Statement on the definition and classification of metabolic hyperferritinaemia	15
How COVID-19 disrupts glycometabolic control	15
Masterful papers that broke open understanding of reproductive neuroendocrinology	15
Metabolic effects of gender-affirming hormone therapy	15
Glial control of neuronal function	14
Senescent immune cells promote skeletal ageing	14
FGF1 signalling cascade suppresses lipolysis	14
Monogenic diabetes mellitus hidden in autoantibody-negative diabetes mellitus	14
The complex effects of dietary restriction on longevity and health	14
New BAT–liver endocrine pathway via succinate	14
A role for HDAC6 in leptin sensitivity	14
Knowledge in youth is wisdom in age: involving young people in research	14
Highlights from ADA 82nd Scientific Sessions	14
Antioxidant liver myeloid cell population identified	14
Environmental factors in declining human fertility	14
AcroBATics: how dying brown adipocytes trigger browning	12
Paracetamol use in pregnancy — neglecting context promotes misinterpretation	12
An updated view on human neonatal thermogenesis	12
The study that pioneered islet isolation techniques	12
Dysfunctional lipid metabolism in ageing muscle: effects on glucose tolerance	12
Author Correction: Seeing through the fog: a neuroendocrine explanation for post-COVID cognitive deficits	12
Obesity induces epigenetic memory in innate immune cells	11

Bone fragility in type 2 diabetes mellitus: a lot left to explore	11
CAMK1D required for ghrelin-mediated food intake	10
Skeletal stem and progenitor cells in bone physiology, ageing and disease	10
IL-17 has a role in whole-body homeostasis	10
Genomics suggest role for IGF1 resistance in T2DM	10
New variant for monogenic obesity	10
The promise of new anti-obesity therapies arising from knowledge of genetic obesity traits	10
Understanding the complexity of insulin resistance	10
Endoscopic sleeve gastroplasty: safe and effective	10
Targeting hyperglucagonaemia in T2DM	10