OOIR: Observatory of International Research

Papers

(The TQCC of Nature Reviews Endocrinology is 14. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-01-01 to 2026-01-01.)

Article	Citations
Exposing skin to ultraviolet irradiation increases food intake in male individuals	834
Author Correction: Adrenocortical stem cells in health and disease	716
Immune cell population prevents weight regain	666
Dexamethasone in patients with diabetes mellitus	641
CNOT6L regulates hepatokine expression	488
Memory of obesity stored in adipocytes	453
Identification of genetic factors of type 2 diabetes mellitus risk in South Asian populations	437
Non-nutritive sweeteners — too sweet to be wholesome?	278
Timed high-fat diet feeding restores small bowel circadian rhythms	248
The role of DNA damage in diabetic complications	219
Effects of diet on atherosclerotic plaque development	199
The challenges of assessing adiposity in a clinical setting	198
Thyroid function and iodine intake: global recommendations and relevant dietary trends	193
Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead	184
Limiting the use and misuse of liothyronine in hypothyroidism	179
The gut microbiota in obesity and weight management: microbes as friends or foe?	176
Ketosis improves muscle stem cell resilience	165
Metabolite levels during the menstrual cycle	162
Patients’ insights into diabetes insipidus	160
mTORC1 is the central regulator in pancreatic β-cells	159
Neurons in the diagonal band of Broca moderate food intake	156
Reply to ‘Ensuring diverse representation and minimizing conflicts of interest in clinical practice guidelines’	140
Ensuring diverse representation and minimizing conflicts of interest in clinical practice guidelines	128
The interactions between energy homeostasis and neurovascular plasticity	124
Midlife and the menopause transition in type 2 diabetes mellitus prevention	123

Steroid hormones as modulators of anti-tumoural immunity	121
Amylin: emergent therapeutic opportunities in overweight, obesity and diabetes mellitus	120
Obesity phenotypes: explaining the unexplained	117
Reply to ‘Why the science on T3 and genomics is not settled’	116
Negative regulator of GDF15 signalling identified	116
Fusion with blood vessel organoids supports pancreatic islet function	111
A pivotal year for NAFLD and NASH therapeutics	106
The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity	103
Primary aldosteronism — a multidimensional syndrome	103
New role for bone marrow adipocytes in obesity	97
A role for phosphocreatine in adipose inflammation	92
Genetic risk scores improve prediction of obesity in survivors of childhood cancer	89
Language evolves — so can you	88
Urocortin 3 function in glucose metabolism	85
RalA links obesity and mitochondrial dysfunction	82
New maps and new challenges in the post-genomic era	81
A role for the kidney in metformin action	81
Progress in islet transplantation is more important than ever	80
The metabolic mythos of ketones	79
GLP1–oestrogen agonist protects β-cells from insulin-deficient diabetes mellitus	79
Inflammation-induced adrenal dysfunction	76
Signals from the dorsal motor nucleus of the vagus promote jejunal fat absorption	75
Advances in incretin-based therapeutics for obesity	72
Advances in basic biology and translation in islet research	71
Epigenetic effects of maternal type 1 diabetes mellitus	69
Luteal phase support in assisted reproductive technology	66
Bone and muscle crosstalk in ageing and disease	65
Endosomal trafficking in metabolic homeostasis and diseases	64
Targeting the incretin system in obesity and type 2 diabetes mellitus	64
Untangling the pathways of SDHx loss of function	63
Triggering puberty in primates: is it NPY?	61
Potential downsides of calorie restriction	60
Leptin–thyroid hormone axis affects energy use in muscle	60
The metabolic benefits of exercise-induced hepatic autophagy	60
Author Correction: Drug Insight: selective agonists and antagonists of the glucocorticoid receptor	60
Islet hormones at the intersection of glucose and amino acid metabolism	59
Tracing the biological roots of obesity resistance in humans	58
A global view of hypertensive disorders and diabetes mellitus during pregnancy	58
Iatrogenic adrenal insufficiency in adults	58
Length of light exposure alters energy metabolism in mice	56
Skeletal and extraskeletal disorders of biomineralization	56
The role of ultra-processed food in obesity	56
REG3G — a potential link between the intestinal microbiome and host physiology	56
HIF1α inhibition preserves β-cell function	55
From the perspective of a scientist with Cushing disease, what did not kill me made my science stronger	53
Vitamin D supplementation and fracture risk	50
Metabolic control of feto–placental development and pregnancy outcomes	49
GLP1 receptor agonist overcomes SGLT2 inhibitor-related overeating	48
Obesity dysregulates a pituitary–liver axis through disruption of the unfolded protein response	46
Remission of T2DM requires early diagnosis and substantial weight reduction	46

The complexity of the relationship between thyroid disease and body weight	46
Investigating the effects of artificial sweeteners	45
Cardiorenal diseases in type 2 diabetes mellitus: clinical trials and real-world practice	43
Sex hormones in SARS-CoV-2 susceptibility: key players or confounders?	43
Continuous glucose monitoring for the routine care of type 2 diabetes mellitus	41
Sarcopenic obesity in older adults: a clinical overview	40
Lipid droplet biogenesis and functions in health and disease	39
Why does the immune system destroy pancreatic β-cells but not α-cells in type 1 diabetes?	38
Engineered Tregs prevent diabetes mellitus in mice	38
Targeting senescent cells in ageing-related endocrine diseases	37
Energy intake at the intersection of the clock and ageing	37
At the 2022 Congress on Obesity	37
Variation in serotonin 2C receptor linked with obesity and behaviour	37
Large study on hormone therapy for transgender youth provides reassurance amid treatment politicization	36
OBEClust: joining forces to prevent obesity	35
Metformin and GDF15: where are we now?	35
Sertoli cell lysosomal dysfunction drives age-related testicular degeneration	33
Arginine vasopressin deficiency: diagnosis, management and the relevance of oxytocin deficiency	32
Exosomes as novel biomarkers in metabolic disease and obesity-related cancers	31
Epigenetics of type 2 diabetes mellitus and weight change — a tool for precision medicine?	30
Mitigating the environmental effects of healthcare: the role of the endocrinologist	30
Growth hormone-releasing hormone and its analogues in health and disease	29
Exercise in adults with type 1 diabetes mellitus	29
The glymphatic system as a nexus between obesity and neurological diseases	28
Interventions in people newly diagnosed with type 1 diabetes mellitus	28
New genes associated with adult-onset obesity	28
Can obesity pharmacotherapy be used to manage male infertility?	27
International consensus guidelines on the implementation and monitoring of vosoritide therapy in individuals with achondroplasia	27
A mitochondrial trigger for beige adipocyte development	27
Brown adipose tissue fights the battle against leukaemia	26
Diabetes mellitus and work participation	26
Nutrient regulation of bone marrow adipose tissue: skeletal implications of weight loss	26
Advancing precision nutrition: bridging mechanistic insight and clinical implementation	25
Medically not yet explained symptoms in hypothyroidism	25
Individualized and innovative gender healthcare for transgender and nonbinary youth	24
The regulation of endocrine-disrupting chemicals to minimize their impact on health	24
GWAS gives insights into glucose regulation	23
SRC2 controls the refeeding response in mice	23
Masterful papers that broke open understanding of reproductive neuroendocrinology	23
Metabolic effects of gender-affirming hormone therapy	23
Monogenic diabetes mellitus hidden in autoantibody-negative diabetes mellitus	22
Combination therapy increases human β-cell mass in vivo	22
Author Correction: International consensus statement on the diagnosis and management of phaeochromocytoma and paraganglioma in children and adolescents	21
Author Correction: Consensus Statement on the definition and classification of metabolic hyperferritinaemia	21
Glial control of neuronal function	21
Sex differences in diabetic kidney disease explained	21
Variation in metformin pharmacokinetics	21
Highlights from ADA 85th Scientific Sessions	21
The complex effects of dietary restriction on longevity and health	21
Negative effects of ultra-processed foods beyond increasing calories	20
Exposure to fat odour during development predisposes offspring to obesity	20
Knowledge in youth is wisdom in age: involving young people in research	19
A role for HDAC6 in leptin sensitivity	19
Unravelling the rise in thyroid cancer incidence and addressing overdiagnosis	19
Antioxidant liver myeloid cell population identified	19
An updated view on human neonatal thermogenesis	18
Highlights from ADA 82nd Scientific Sessions	18
FGF1 signalling cascade suppresses lipolysis	18
Author Correction: Seeing through the fog: a neuroendocrine explanation for post-COVID cognitive deficits	18
AcroBATics: how dying brown adipocytes trigger browning	18
Advances in incretin-based drug discovery in 2025	17
The study that pioneered islet isolation techniques	17
Obesity induces epigenetic memory in innate immune cells	17
Bone fragility in type 2 diabetes mellitus: a lot left to explore	17
Consensus on acromegaly therapeutic outcomes: an update	17
Skeletal stem and progenitor cells in bone physiology, ageing and disease	17
CAMK1D required for ghrelin-mediated food intake	16
Dysfunctional lipid metabolism in ageing muscle: effects on glucose tolerance	16
Genomics suggest role for IGF1 resistance in T2DM	16
New variant for monogenic obesity	16
Paracetamol use in pregnancy — neglecting context promotes misinterpretation	16
Endoscopic sleeve gastroplasty: safe and effective	15
IL-17 has a role in whole-body homeostasis	15
Targeting hyperglucagonaemia in T2DM	14
Antigen-specific Treg cells induce infectious tolerance	14
Understanding the complexity of insulin resistance	14