OOIR: Observatory of International Research

Papers

(The TQCC of Nature Reviews Endocrinology is 17. The table below lists those papers that are above that threshold based on CrossRef citation counts [max. 250 papers]. The publications cover those that have been published in the past four years, i.e., from 2022-05-01 to 2026-05-01.)

Article	Citations
Exposing skin to ultraviolet irradiation increases food intake in male individuals	952
Immune cell population prevents weight regain	576
Memory of obesity stored in adipocytes	534
Identification of genetic factors of type 2 diabetes mellitus risk in South Asian populations	520
Non-nutritive sweeteners — too sweet to be wholesome?	309
Author Correction: Adrenocortical stem cells in health and disease	263
Timed high-fat diet feeding restores small bowel circadian rhythms	234
CNOT6L regulates hepatokine expression	233
The challenges of assessing adiposity in a clinical setting	223
The gut microbiota in obesity and weight management: microbes as friends or foe?	222
Thyroid function and iodine intake: global recommendations and relevant dietary trends	219
Harnessing cellular therapeutics for type 1 diabetes mellitus: progress, challenges, and the road ahead	210
Effects of diet on atherosclerotic plaque development	206
Limiting the use and misuse of liothyronine in hypothyroidism	192
The role of DNA damage in diabetic complications	187
Ketosis improves muscle stem cell resilience	184
Patients’ insights into diabetes insipidus	177
Neurons in the diagonal band of Broca moderate food intake	152
Reply to ‘Ensuring diverse representation and minimizing conflicts of interest in clinical practice guidelines’	143
Ensuring diverse representation and minimizing conflicts of interest in clinical practice guidelines	141
A pivotal year for NAFLD and NASH therapeutics	140
Amylin: emergent therapeutic opportunities in overweight, obesity and diabetes mellitus	137
Fusion with blood vessel organoids supports pancreatic islet function	136
Reply to ‘Why the science on T3 and genomics is not settled’	136
mTORC1 is the central regulator in pancreatic β-cells	130

Obesity phenotypes: explaining the unexplained	127
Primary aldosteronism — a multidimensional syndrome	119
Midlife and the menopause transition in type 2 diabetes mellitus prevention	113
Steroid hormones as modulators of anti-tumoural immunity	112
The evolving functions of the vasculature in regulating adipose tissue biology in health and obesity	104
The interactions between energy homeostasis and neurovascular plasticity	101
New role for bone marrow adipocytes in obesity	99
Genetic risk scores improve prediction of obesity in survivors of childhood cancer	96
A role for the kidney in metformin action	94
Language evolves — so can you	87
Signals from the dorsal motor nucleus of the vagus promote jejunal fat absorption	85
The metabolic mythos of ketones	85
Epigenetic effects of maternal type 1 diabetes mellitus	83
Inflammation-induced adrenal dysfunction	83
Advances in basic biology and translation in islet research	82
New maps and new challenges in the post-genomic era	80
Endosomal trafficking in metabolic homeostasis and diseases	78
Progress in islet transplantation is more important than ever	78
Dysfunctional adipose tissue–lymphatic crosstalk in obesity	77
Advances in incretin-based therapeutics for obesity	77
RalA links obesity and mitochondrial dysfunction	77
Bone and muscle crosstalk in ageing and disease	76
Luteal phase support in assisted reproductive technology	74
Targeting the incretin system in obesity and type 2 diabetes mellitus	74
Untangling the pathways of SDHx loss of function	73
Author Correction: Drug Insight: selective agonists and antagonists of the glucocorticoid receptor	72
REG3G — a potential link between the intestinal microbiome and host physiology	71
Leptin–thyroid hormone axis affects energy use in muscle	71
Iatrogenic adrenal insufficiency in adults	70
Tracing the biological roots of obesity resistance in humans	70
Skeletal and extraskeletal disorders of biomineralization	68
Islet hormones at the intersection of glucose and amino acid metabolism	65
The metabolic benefits of exercise-induced hepatic autophagy	63
A global view of hypertensive disorders and diabetes mellitus during pregnancy	63
The role of ultra-processed food in obesity	63
Potential downsides of calorie restriction	62
Length of light exposure alters energy metabolism in mice	60
Vitamin D supplementation and fracture risk	60
From the perspective of a scientist with Cushing disease, what did not kill me made my science stronger	60
GLP1 receptor agonist overcomes SGLT2 inhibitor-related overeating	55
GPR110 as a regulator of MASH	54
The autonomic nervous system in the regulation of glucose and lipid metabolism	54
Metabolic control of feto–placental development and pregnancy outcomes	49
Sex hormones in SARS-CoV-2 susceptibility: key players or confounders?	48
The complexity of the relationship between thyroid disease and body weight	47
Obesity dysregulates a pituitary–liver axis through disruption of the unfolded protein response	47
Why does the immune system destroy pancreatic β-cells but not α-cells in type 1 diabetes?	46
Cardiorenal diseases in type 2 diabetes mellitus: clinical trials and real-world practice	46
Investigating the effects of artificial sweeteners	46
Continuous glucose monitoring for the routine care of type 2 diabetes mellitus	45

Sarcopenic obesity in older adults: a clinical overview	44
Lipid droplet biogenesis and functions in health and disease	43
Engineered Tregs prevent diabetes mellitus in mice	43
At the 2022 Congress on Obesity	42
Sertoli cell lysosomal dysfunction drives age-related testicular degeneration	42
Variation in serotonin 2C receptor linked with obesity and behaviour	41
Targeting senescent cells in ageing-related endocrine diseases	41
OBEClust: joining forces to prevent obesity	40
Energy intake at the intersection of the clock and ageing	40
ZMIZ1 supports endometrial oestrogen and progesterone signalling	39
Highlights from SfE BES 2026	37
Metformin and GDF15: where are we now?	37
The glymphatic system as a nexus between obesity and neurological diseases	37
Large study on hormone therapy for transgender youth provides reassurance amid treatment politicization	37
Growth hormone-releasing hormone and its analogues in health and disease	36
Arginine vasopressin deficiency: diagnosis, management and the relevance of oxytocin deficiency	36
Mitigating the environmental effects of healthcare: the role of the endocrinologist	35
Epigenetics of type 2 diabetes mellitus and weight change — a tool for precision medicine?	35
Exercise in adults with type 1 diabetes mellitus	35
New genes associated with adult-onset obesity	34
Nutrient regulation of bone marrow adipose tissue: skeletal implications of weight loss	34
Models of hyperglycaemia in diabetes mellitus and its complications	34
Can obesity pharmacotherapy be used to manage male infertility?	33
Individualized and innovative gender healthcare for transgender and nonbinary youth	33
Advancing precision nutrition: bridging mechanistic insight and clinical implementation	33
A mitochondrial trigger for beige adipocyte development	33
Diabetes mellitus and work participation	32
GWAS gives insights into glucose regulation	32
Greater recognition required for thyroid disorders	31
Interventions in people newly diagnosed with type 1 diabetes mellitus	31
Brown adipose tissue fights the battle against leukaemia	31
Medically not yet explained symptoms in hypothyroidism	30
International consensus guidelines on the implementation and monitoring of vosoritide therapy in individuals with achondroplasia	29
Blood-based obesity biomarkers and their relevance for disease risk	29
The regulation of endocrine-disrupting chemicals to minimize their impact on health	28
Masterful papers that broke open understanding of reproductive neuroendocrinology	28
Metabolic effects of gender-affirming hormone therapy	28
Highlights from ADA 85th Scientific Sessions	27
Combination therapy increases human β-cell mass in vivo	27
The complex effects of dietary restriction on longevity and health	27
Variation in metformin pharmacokinetics	26
Negative effects of ultra-processed foods beyond increasing calories	26
Knowledge in youth is wisdom in age: involving young people in research	26
Author Correction: International consensus statement on the diagnosis and management of phaeochromocytoma and paraganglioma in children and adolescents	26
The public health burden of diabetes mellitus and thyroid disease: twin epidemics	26
Sex differences in diabetic kidney disease explained	25
Author Correction: Consensus Statement on the definition and classification of metabolic hyperferritinaemia	25
Exposure to fat odour during development predisposes offspring to obesity	25
Neurokinin receptor antagonists for vasomotor symptoms: from KNDy neurons to clinical translation	24
Monogenic diabetes mellitus hidden in autoantibody-negative diabetes mellitus	24
Antioxidant liver myeloid cell population identified	23
Unravelling the rise in thyroid cancer incidence and addressing overdiagnosis	23
Peritumoural adipose tissue protects colorectal cancer from immune attack	23
Highlights from ADA 82nd Scientific Sessions	22
The study that pioneered islet isolation techniques	21
AcroBATics: how dying brown adipocytes trigger browning	21
Advances in incretin-based drug discovery in 2025	20
Author Correction: Seeing through the fog: a neuroendocrine explanation for post-COVID cognitive deficits	20
Obesity induces epigenetic memory in innate immune cells	20
Skeletal stem and progenitor cells in bone physiology, ageing and disease	20
Consensus on acromegaly therapeutic outcomes: an update	19
Dysfunctional lipid metabolism in ageing muscle: effects on glucose tolerance	19
Genomics suggest role for IGF1 resistance in T2DM	18
Bone fragility in type 2 diabetes mellitus: a lot left to explore	18
CAMK1D required for ghrelin-mediated food intake	18
New variant for monogenic obesity	17
Targeting hyperglucagonaemia in T2DM	17
IL-17 has a role in whole-body homeostasis	17
Antigen-specific Treg cells induce infectious tolerance	17
Endoscopic sleeve gastroplasty: safe and effective	17